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Christopher Nance, MD

Clinical Associate Professor of Neurology

Current Positions

  • Clinical Associate Professor of Neurology

Education

  • BS in Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
  • MD in Medicine, Winston-Salem, North Carolina, United States
  • Internship in Medicine, Mayo Graduate School of Medicine, Rochester, Minnesota, United States
  • Resident in Neurology, Mayo Graduate School of Medicine, Rochester, Minnesota, United States
  • Fellow in Peripheral Nerves, Mayo Graduate School of Medicine, Rochester, Minnesota, United States
  • Fellow in Clinical Neurophysiology / Electromyography, Mayo Graduate School of Medicine, Rochester, Minnesota, United States

Research Interests

  • A Double-Bli nd, Randomized, Placebo-Contro lled, Multicenter Study to Assess the Safety and Efficacy, and to Determine the Pharmacokinetics of Two Doses of AVP- 923 (Dextromethoraphan/Quinidine) in the Treatment of Pseudobulbar Affect (PBA) in Patients with Amyotrophic Lateral Sclerosis and Multiple Sclerosis. Sponsor : Avanir Pharmaceuticals (2007 - 2009). Co-Investigator.
  • Non-Invasive Neurostimulation of the Vagus Nerve With the GammaCore® Device for the Treatment of Cluster Headache (Protocol CH-US-01). Sponsor: ElectroCore, LLC. (2013-2014). Co-Investigator.
  • A Phase IIB, Multi-National , Double-Blind , Randomized, Placebo-Controlled Study To Evaluate The Safety, Tolerability And Efficacy of CK-2017357 In Patients With Amyotroph ic Lateral Sclerosis (ALS) (Protocol CY 4026). Sponsor: Cytokinetics. (20 13-20 14). Co-Investigator.
  • Controlled Trial of 3, 4 Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (LEMS). Sponsor: Jacobus Pharmaceutical Company, Inc. In Progress. Co-Investigator
  • Amyotroph i c Lateral Sclerosis Research Group [ALS RG] Collection of Date and Biomaterial for Repository Banking to Facilitate Research into the Etiology of Amyotrophic Lateral Sclerosis and Related Motor Neuron Disease. Sponsors: National Institutes of Health, Muscu lar Dystrophy Association and Amyotrophic Latera l Sclerosis Association (2006-2007). Co-Investigator.
  • A 12-month, £rospective, Randomized , active-controlled , open-label study to gvaluate the patient retention of .Eingolimod vs. approved first-line disease modifying therapies in adults who are in garly Stages of treatment for Relapsing remitting Multiple .S.clerosis (PREFERMS) (Protocol CFTY720DUS09). Sponsor: Novart is. ln Progress (Start 2012). Co-Investigator.
  • Stenting and Aggressive Medical Management for Preventing Recurrent stroke in lntracranial Stenosis (SAMMPRIS). Sponsor: NINDS. In Progress. Co-Investigator.
  • MS 2302: A 12-Month Double-Blind , Randomized , Multicenter , Active-Controlled , Parallel-Group Study Comparing the Efficacy and Safety of 0.5 mg and 1.25 mg Fingoli mod (FTY720) Administered Orally Once Daily Versus Interferon P-1a (Avonex7) Administered l.M. Once Weekly in Patients With Relapsing-Remi tt ing Multiple Sclerosis with Optional Extension Phase (Protocol Number CFTY720D2302). Sponsor: Novartis. (2007-201 1). Co-Investigator.
  • MS 2309: A 24-Month Double-Blind, Randomized, Multicenter , Placebo-Controlled, Parallel -Group Study Comparing the Efficacy and Safety of 0.5 mg and 1 .25 mg Fingol imod (FTY720) Administered Orally Once Da ily Versus Placebo in Patients With Relapsing-Remitting Multiple Sclerosis (Protocol No. CFTY720D2309). Sponsor: Novartis. (2007-20 12). Co-Investigator.

Licenses & Certifications

  • Medical License, West Virginia Medical Board, West Virginia
  • Neuromuscular - Peripheral Nerve Pathology Certification, American Academy of Neurology
  • Board Certified, American Board of Psychiatry and Neurology
  • Neuromuscular Subspecialty Certification, American Board of Psychiatry and Neurology
  • Clinical Neurophysiology Subspecialty Certification, American Board of Psychiatry and Neurology
  • Medical License, Minnesota Medical Board, Minnesota

Selected Publications

  • Wolff, A. A., Meng, L., Bian, A., Lee, J., Barragan, D., Andrews, J. A., Benefit ALS Study Group & Shefner, J. M. (2016). A randomized, placebo-controlled, double-blind phase IIb trial evaluating the safety and efficacy of tirasemtiv in patients with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration 17 (5-6) 426-35. PMID: 26982815. DOI: 10.3109/21678421.2016.1148169.
  • Weimer, T., Nance, C. & Watson, D. (2013). Neuropathy following laparoscopic adjustable gastric banding: treatment with plasmapheresis. The West Virginia medical journal 109 (1) 16-7. PMID: 23413542.
  • Mauermann, M. L., Scheithauer, B. W., Spinner, R. J., Amrami, K. K., Nance, C. S., Kline, D. G., O'Connor, M. I., Dyck, P. J., Engelstad, J. & Dyck, P. J. (2010). Inflammatory pseudotumor of nerve: clinicopathological characteristics and a potential therapy. Journal of the peripheral nervous system : JPNS 15 (3) 216-26. DOI: 10.1111/j.1529-8027.2010.00273.x. PMID: 21040144.
  • Gutmann, L. & Nance, C. (2010). The illusion of severe carpal tunnel syndrome (CTS). Muscle & nerve 41 (2) 260-1. DOI: 10.1002/mus.21547. PMID: 19918777.
  • Nance, C. S. & Gutmann, L. (2010). Neurogastro intestinal encephalomyopathy. In Companion to Peripheral neuropathy : illustrated cases and new developments. pp. 163-166. Philadelphia, PA: Saunders/Elsevier.
  • L, G. & Nance, C. S. (2009). Mitochondrial Neuropathy of MNGIE. Journal of the Peripheral Nervous System 14 (2) 61.
  • Nance, C. S., Klein, C. J., Banikazemi, M., Dikman, S. H., Phelps, R. G., McArthur, J. C., Rodriguez, M. & Desnick, R. J. (2006). Later-onset Fabry disease: an adult variant presenting with the cramp-fasciculation syndrome. Archives of neurology 63 (3) 453-7. DOI: 10.1001/archneur.63.3.453. PMID: 16533976.