HyungSub Shim, MD

Portrait
Medical Director: Neuroscience Intermediate Care Unit
Director: Memory Disorders Clinic
Specialty: Dementia
Clinical Assistant Professor of Neurology
Clinical Assistant Professor of Psychiatry

Contact Information

Primary Office
2155 RCP
Iowa City, IA 52242
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Education

BA, Linguistics, Neuroscience, Biology, Lawrence University
MD, Medical College of Wisconsin
Internship, Internal Medicine, University of Iowa Hospitals and Clinics
Chief Resident, Neurology, University of Iowa Hospitals and Clinics
Resident, Neurology, University of Iowa Hospitals and Clinics
Fellow, Behavioral Neurology and Neuropsychiatry, Northwestern University

Licensure and Certifications

Iowa Medical License - Iowa Board of Medicine
Behavioral Neurology and Neuropsychiatry - United Council of Neurologic Subspecialties
Neurology - American Board of Psychiatry and Neurology

Publications

Shim, H., Tranel, D. (In Press). Behavioral neurology. In R. N. Rosenberg (Eds.) Atlas of clinical neurology. (4th edition) Philadelphia, PA: Springer.

Shim, H., Im, K. B. & Culebras, A. (2016). Sleep and dementia. MedLink Corp.,(March 7 2016 update).

Risacher, S., McDonald, B., Tallman, E., West, J., Farlow, M., Unverzagt, F., Gao, S., Boustani, M., Crane, P., Petersen, R., Jack, Jr., C., Jagust, W., Aisen, P., Weiner, M., Saykin, A., Trojanowki, J., Toga, A., Beckett, L., Green, R., Morris, J., Shaw, L., Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R., Foster, N., Reiman, E., Chen, K., Mathis, C., Landau, S., Cairns, N., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M., Grossman, H., Mitsis, E., Shah, R., De, T., Duara, R., Varon, D., Greig, M., Roberts, P., Onyike, C., D’Agostino, II, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De, L., Glodzik, L., De, S., Murali, D., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Arnold, S., Karlawish, J., Wolk, D., Clark, C., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O., Oakley, M., Simpson, D., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Saleem, I., Brand, C., Mulnard, R., Thai, G., McAdams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Van, D., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C., Johnson, N., Sadowsky, C., Villena, T., Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Carmichael, O., Kittur, S., Borrie, M., Lee, T., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pasternak, S., Rachinsky, I., Rogers, J., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S., Boles, P., Shim, H., Smith, K., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok, R., Fargher, K., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., Doraiswamy, P., James, O., Goldstei, B., Martin, K., Massoglia, D., Brawman-Mintzer, O., Martinez, W., Ros, H., Behan, K., Sirrel, S., Johnson, S., Fruehling, J., Harding, S., Peskind, E., Petrie, E., Li, G., Yesavage, J., Furst, A. & Chao, S. (2016). Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults. JAMA Neurology, 73(6), 721–732. DOI: 10.1001/jamaneurol.2016.0580.

Iturria-Medina, Y., Sotero, R., Toussaint, P., Mateos-Pérez, J., Evans, A., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Khachaturian, Z., Sorensen, G., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R., Foster, N., Reiman, E., Chen, K., Mathis, C., Landau, S., Cairns, N., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Leon, S., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., De, T., Shah, R., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D’Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Rusinek, H., De, L., Glodzik, L., De, S., Doraiswamy, P., Petrella, J., Wong, T., Arnold, S., Karlawish, J., Wolk, D., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O., Oakley, M., Simpson, D., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., DeVous, M., Levey, A., Lah, J., Cellar, J., Burns, J., Anderson, H., Swerdlow, R., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A., Matthews, B., Herring, S., Hunt, C., Van, D., Carson, R., MacAvoy, M., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Bernick, C., Munic, D., Kerwin, D., Mesulam, M., Lipowski, K., Wu, C., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Frey, M., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., DeCarli, C., Kittur, S., Borrie, M., Lee, T., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Santulli, R., Kitzmiller, T., Schwartz, E., Sink, K., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S., Ponto, L., Shim, H., Smith, K., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K., Raj, B., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., James, O., Massoglia, D., Fruehling, J., Harding, S., Peskind, E., Petrie, E., Li, G., Yesavage, J., Taylor, J. & Furst, A. (2016). Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis. Nature Communications, 7. DOI: 10.1038/ncomms11934.

Shim, H., Miller, A., Gehl, C. & Paulsen, J. S. (2016). Behavior and personality differences. In R. B. Daroff , J. Jankovic , J. C. Mazziotta & S. L. Pomeroy , W. G. Bradley (Eds.) Bradley's Neurology in Clinical Practice. (Seventh edition), pp. 73-91.e4. Elsevier.

Shim, H., Ly, M. J. & Tighe, S. K. (2015). Brain imaging in the differential diagnosis of young-onset dementias. The Psychiatric clinics of North America, 38(2), 281-94. PMID: 25998116.

Ayton, S., Faux, N., Bush, A., Weiner, M., Aisen, P., Petersen, R., Jack, Jr., C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Khachaturian, Z., Sorensen, G., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R., Foster, N., Reiman, E., Chen, K., Mathis, C., Landau, S., Cairns, N., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T., Potkin, S., Shen, L., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Leon, S., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., De, T., Shah, R., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D’Agostino, II, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Rusinek, H., De, L., Glodzik, L., De, S., Doraiswamy, P., Petrella, J., Wong, T., Arnold, S., Karlawish, J., Wolk, D., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O., Oakley, M., Simpson, D., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., DeVous, M., Levey, A., Lah, J., Cellar, J., Burns, J., Anderson, H., Swerdlow, R., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A., Matthews, B., Herring, S., Hunt, C., Van, D., Carson, R., MacAvoy, M., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Bernick, C., Munic, D., Kerwin, D., Mesulam, M., Lipowski, K., Wu, C., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Frey, M., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., DeCarli, C., Kittur, S., Borrie, M., Lee, T., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Santulli, R., Kitzmiller, T., Schwartz, E., Sink, K., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S., Boles, P., Shim, H., Smith, K., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K., Raj, B., Neylan, T., Grafman, J., Davis, M., Morrison, R., Hayes, J., Finley, S., Friedl, K., Fleischman, D., Arfanakis, K., James, O., Massoglia, D., Fruehling, J., Harding, S., Peskind, E., Petrie, E., Li, G., Yesavage, J., Taylor, J. & Furst, A. (2015). Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE. Nature Communications, 6. DOI: 10.1038/ncomms7760.

Bit-Ivan, E. N., Suh, E., Shim, H. S., Weintraub, S., Hyman, B. T., Arnold, S. E., McCarty-Wood, E., Van Deerlin, V. M., Schneider, J. A., Trojanowski, J. Q., Frosch, M. P., Baker, M. C., Rademakers, R., Mesulam, M. & Bigio, E. H. (2014). A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. Journal of neuropathology and experimental neurology, 73(5), 467-73. PMID: 24709683.

Shim, H. (2014). Vascular cognitive impairment and post-stroke cognitive deficits. Current neurology and neuroscience reports, 14(1), 418. PMID: 24272272.

Shim, H., Hurley, R. S., Rogalski, E. & Mesulam, M. M. (2012). Anatomic, clinical, and neuropsychological correlates of spelling errors in primary progressive aphasia. Neuropsychologia, 50(8), 1929-35. PMID: 22579708.

Shim, H., Grabowski, T. (2010). Comprehension. (4), pp. 45-58. Continuum Lifelong Learning Neurology.