Profiles people listing in a scrolling container.
  1. Home
  2. People

Jan R. Wessel, PhD

Associate Professor of Neurology

Introduction

Our research examines the neural mechanisms that underlie flexible behavior and cognition.

We are interested in how humans carry out and maintain goal-directed behaviors; specifically, how the cognitive system resolves challenges to this goal. Common examples of such challenges are unexpected events and action errors.

We investigate the dynamic interplay between brain networks that subserve:

  • The monitoring of the external and internal environment.
  • The evaluation of action outcomes.
  • The adaptation of ongoing behavior and cognition in the short and long term.

We use a variety of methods to study these questions, including (but not limited to):

  • Scalp-recorded Electroencephalography (EEG).
  • Invasive recordings of brain activity (ECoG and DBS-LFP recordings).
  • Transcranial magnetic stimulation (TMS).
  • Functional Magnetic Resonance Imaging (fMRI).
  • Computational modeling.
  • Autonomic psychophysiology.

Finally, we study how pathological processes, brain lesions, and (ab)normal aging affect these networks.

Current Positions

  • Associate Professor of Neurology
  • Associate Professor of Psychological and Brain Sciences

Education

  • M.Sc. equivalent in Psychology, University of Cologne, Cologne, Germany
  • PhD in Cognitive Neurology, Max Planck Institute for Neurological Research, Cologne, Germany
  • Postdoctoral Fellow in Cognitive Neuroscience, University of California, San Diego, San Diego, California, United States

Graduate Program Affiliations

Center, Program and Institute Affiliations

Selected Publications

  • Dykstra, T., Waller, D. A., Hazeltine, E. & Wessel, J. R. (In Press). Leveling the field for a fairer race between going and stopping: Neural evidence for the race model of motor inhibition from a new version of the stop-signal task. Journal of Cognitive Neuroscience.
  • Wessel, J. R. & Huber, D. E. (2019). Frontal cortex tracks surprise separately for different sensory modalities but engages a common inhibitory control mechanism. PLoS computational biology 15 (7) e1006927. DOI: 10.1371/journal.pcbi.1006927. PMID: 31356593.
  • Wessel, J. R., Waller, D. A. & Greenlee, J. D. (2019). Non-selective inhibition of inappropriate motor-tendencies during response-conflict by a fronto-subthalamic mechanism. eLife 8. DOI: 10.7554/eLife.42959. PMID: 31063130. PMCID: PMC6533064.
  • Verbruggen, F., Aron, A. R., Band, G. P., Beste, C., Bissett, P. G., Brockett, A. T., Brown, J. W., Chamberlain, S. R., Chambers, C. D., Colonius, H., Colzato, L. S., Corneil, B. D., Coxon, J. P., Dupuis, A., Eagle, D. M., Garavan, H., Greenhouse, I., Heathcote, A., Huster, R. J., Jahfari, S., Kenemans, J. L., Leunissen, I., Li, C. R., Logan, G. D., Matzke, D., Morein-Zamir, S., Murthy, A., Paré, M., Poldrack, R. A., Ridderinkhof, K. R., Robbins, T. W., Roesch, M., Rubia, K., Schachar, R. J., Schall, J. D., Stock, A. K., Swann, N. C., Thakkar, K. N., van der Molen, M. W., Vermeylen, L., Vink, M., Wessel, J. R., Whelan, R., Zandbelt, B. B. & Boehler, C. N. (2019). A consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal task. eLife 8. DOI: 10.7554/eLife.46323. PMID: 31033438. PMCID: PMC6533084.
  • Wessel, J. R., Gorgolewski, K. J. & Bellec, P. (2019). Switching Software in Science: Motivations, Challenges, and Solutions. Trends in cognitive sciences. DOI: 10.1016/j.tics.2019.01.004. PMID: 30712996.
  • Waller, D. A., Hazeltine, E. & Wessel, J. R. (2019). Common neural processes during action-stopping and infrequent stimulus detection: The frontocentral P3 as an index of generic motor inhibition. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. DOI: 10.1016/j.ijpsycho.2019.01.004. PMID: 30659867.
  • Wessel, J. R. (2018). Surprise: A More Realistic Framework for Studying Action Stopping?. Trends in cognitive sciences 22 (9) 741-744. DOI: 10.1016/j.tics.2018.06.005. PMID: 30122169.
  • Wessel, J. R. (2018). An adaptive orienting theory of error processing. Psychophysiology 55 (3). DOI: 10.1111/psyp.13041. PMID: 29226960.
  • Dutra, I. C., Waller, D. A. & Wessel, J. R. (2018). Perceptual Surprise Improves Action Stopping by Nonselectively Suppressing Motor Activity via a Neural Mechanism for Motor Inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (6) 1482-1492. DOI: 10.1523/JNEUROSCI.3091-17.2017. PMID: 29305533.
  • Kelley, R., Flouty, O., Emmons, E. B., Kim, Y., Kingyon, J., Wessel, J. R., Oya, H., Greenlee, J. D. & Narayanan, N. S. (2018). A human prefrontal-subthalamic circuit for cognitive control. Brain : a journal of neurology 141 (1) 205-216. DOI: 10.1093/brain/awx300. PMID: 29190362.