Catherine A. Marcinkiewcz, PhD

Assistant Professor of Neuroscience and Pharmacology

Contact Information

Primary Office
2-432 BSB
51 Newton Rd.
Iowa City, IA 52242

2-400 BSB
Iowa City, IA 52242


MS, Biomedical Engineering, Department of Biomedical Engineering, University of Florida
PhD, Neuroscience, Interdisciplinary Program in Biomedical Sciences, University of Florida
Postdoctoral Fellow, Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience

Center, Program and Institute Affiliations

Iowa Neuroscience Institute


Radke, A. K., Jury, N. J., Kocharian, A., Marcinkiewcz, C. A., Lowery-Gionta, E. G., Pleil, K. E., McElligott, Z. A., McKlveen, J. M., Kash, T. L. & Holmes, A. (2017). Chronic EtOH effects on putative measures of compulsive behavior in mice. Addiction Biology, 22(2), 423-434. PMID: 26687341.

Marcinkiewcz, C. A., Mazzone, C. M., D'Agostino, G., Halladay, L. R., Hardaway, J. A., DiBerto, J. F., Navarro, M., Burnham, N., Cristiano, C., Dorrier, C. E., Tipton, G. J., Ramakrishnan, C., Kozicz, T., Deisseroth, K., Thiele, T. E., McElligott, Z. A., Holmes, A., Heisler, L. K. & Kash, T. L. (2016). Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala. Nature, 537(7618), 97-101. PMID: 27556938.

Marcinkiewcz, C. A., Lowery-Gionta, E. G. & Kash, T. L. (2016). Serotonin's Complex Role in Alcoholism: Implications for Treatment and Future Research. Alcoholism, Clinical and Experimental Research, 40(6), 1192-201. PMID: 27161942.

Urban, D. J., Zhu, H., Marcinkiewcz, C. A., Michaelides, M., Oshibuchi, H., Rhea, D., Aryal, D. K., Farrell, M. S., Lowery-Gionta, E., Olsen, R. H., Wetsel, W. C., Kash, T. L., Hurd, Y. L., Tecott, L. H. & Roth, B. L. (2016). Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons. Neuropsychopharmacology, 41(5), 1404-15. PMID: 26383016.

Pleil, K. E., Lowery-Gionta, E. G., Crowley, N. A., Li, C., Marcinkiewcz, C. A., Rose, J. H., McCall, N. M., Maldonado-Devincci, A. M., Morrow, A. L., Jones, S. R. & Kash, T. L. (2015). Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala. Neuropharmacology, 99, 735-49. PMID: 26188147.

Marcinkiewcz, C. A. (2015). Serotonergic Systems in the Pathophysiology of Ethanol Dependence: Relevance to Clinical Alcoholism. ACS Chemical Neuroscience, 6(7), 1026-39. PMID: 25654315.

Marcinkiewcz, C. A., Devine, D. P. (2015). Modulation of OCT3 expression by stress, and antidepressant-like activity of decynium-22 in an animal model of depression. Pharmacology, Biochemistry, and Behavior, 131, 33-41. PMID: 25597272.

Marcinkiewcz, C. A., Dorrier, C. E., Lopez, A. J. & Kash, T. L. (2015). Ethanol induced adaptations in 5-HT2c receptor signaling in the bed nucleus of the stria terminalis: implications for anxiety during ethanol withdrawal. Neuropharmacology, 89, 157-67. PMID: 25229718.

Lowery-Gionta, E. G., Marcinkiewcz, C. A. & Kash, T. L. (2015). Functional alterations in the dorsal raphe nucleus following acute and chronic ethanol exposure. Neuropsychopharmacology, 40(3), 590-600. PMID: 25120075.

Kash, T. L., Pleil, K. E., Marcinkiewcz, C. A., Lowery-Gionta, E. G., Crowley, N., Mazzone, C., Sugam, J., Hardaway, J. A. & McElligott, Z. A. (2015). Neuropeptide regulation of signaling and behavior in the BNST. Molecules and Cells, 38(1), 1-13. PMID: 25475545.

Al-Hasani, R., McCall, J. G., Shin, G., Schmitz, G. P., Bernardi, J. M., Pyo, C. O., Park, S. I., Marcinkiewcz, C. A., Crowley, N. A., Krashes, M. J., Lowell, B. B., Kash, T. L., Rogers, J. A. & Bruchas, M. R. (2015). Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward. Neuron, 87(5), 1063-77. PMID: 6335648.

Holmes, A., Fitzgerald, P. J., MacPherson, K. P., DeBrouse, L., Colacicco, G., Flynn, S. M., Masneuf, S., Pleil, K. E., Li, C., Marcinkiewcz, C. A., Kash, T. L., Gunduz-Cinar, O. & Camp, M. (2012). Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nature Neuroscience, 15(10), 1359-61. PMID: 22941108.

Marcinkiewcz, C. A., Prado, M. M., Isaac, S. K., Marshall, A., Rylkova, D. & Bruijnzeel, A. W. (2009). Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats. Neuropsychopharmacology, 34(7), 1743-52. PMID: 19145226.

Marcinkiewcz, C. A., Green, M. K., Devine, D. P., Duarte, P., Vierck, C. J. & Yezierski, R. P. (2009). Social defeat stress potentiates thermal sensitivity in operant models of pain processing. Brain Research, 1251, 112-20. PMID: 19059227.

Bruijnzeel, A. W., Marcinkiewcz, C., Isaac, S., Booth, M. M., Dennis, D. M. & Gold, M. S. (2007). The effects of buprenorphine on fentanyl withdrawal in rats. Psychopharmacology, 191(4), 931-41. PMID: 17211652.