Christopher Clark, MD
Clinical Assistant Professor of Obstetrics and Gynecology, Division of Maternal Fetal Medicine
Primary Office
Current Positions
- Clinical Assistant Professor - Obstetrics and Gynecology, Division of Maternal Fetal Medicine
Education
- BS in Molecular Biology - Auburn University Honors College, Auburn, Alabama
- Doctor of Medicine - Medical University of South Carolina, Charleston, South Carolina
- Resident in Obstetrics and Gynecology - Medical College of Georgia, Augusta, Georgia
- Fellow in Maternal Fetal Medicine - University of Iowa Carver College of Medicine, Iowa City, Iowa
Research Interests
- 2021 – current: Prevention of Preeclampsia via Modulation of RGS2 Signaling.
- 2019-2020: OB/Gyn Resident Research
- 2014-2015: Howard Hughes Medical Research Fellow
- 2008-2011: Research Specialist
Selected Publications
- Barth J, Clark C, Fresco V, Knoll E, Argraves S, Lee K. Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis. Developmental Dynamics. 239:2024-2033, 2010. PMID: 20549724
- Clark C, Zhang B, Lee B, Evans S, Lassar A, Lee K. Evolutionary Conservation of Nkx2.5 Autoregulation in the Second Heart Field. Developmental Biology. 374:198-209, 2012. PMID: 23165293
- Burke S, Zsengeller Z, Rajakumar A, Khankin E, McCurley A, Dupont J, Zhang D, Clark C, Wang A, Seely E, Kang P, Stillman I, Jaffe I, Karumanchi S. Soluble Fms-like Tyrosine Kinase 1 promotes Angiotensin II Sensitivity during Preeclampsia by Impairing Nitric Oxide Synthesis and Inducing Oxidative Stress. Journal of Clinical Investigation. 126(7): 2561–2574, 2016. PMID: 27270170
- Clark C, Street L. Commentary of “The incidence, characteristics, management and outcomes of anaphylaxis in pregnancy: a population-based descriptive study, McCall S, Bunch K, Brocklehurst P, D’Arcy R, Hinshaw K, Kurinczuk J, Lucas D, Stenson B, Tuffnell D, Knighta M. BJOG 2018;125:965-971”. Obstetric Anesthesia Digest. 39(2):78-80, 2019.
- Clark C, Lee K. Second Heart Field-Specific Expression of Nkx2-5 requires Promoter Proximal Interaction with SRF. Mechanisms of Development. 2020 June; 103615. PMID 32450132
- Horton A, Brooker J, Flessa M, Clark C, Simpson R, Gooz M, Foley A, Lee K. NKX 2.5 Second Heart Field Target Gene Ccdc117 Regulates DNA Metabolism and Proliferation. Scientific Reports. 9(1):1738, 2019. PMID: 30742009