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Jesus Gonzalez Bosquet, MD, PhD

Associate Professor of Obstetrics and Gynecology-Gynecologic Oncology

Current Positions

  • Associate Professor of Obstetrics and Gynecology - Gynecologic Oncology

Education

  • MD in Medicine, Medical School of the University of Barcelona (www.ub.es)
  • PhD in Department of Pediatrics, Obstetrics and Gynecology, and Preventive Medicine, Medical School of the Autonomous University of Barcelona, Barcelona, Spain
  • MSc in Master of Biomedical Science, Gynecologic Oncology, Mayo Graduate School, Rochester, Minnesota
  • Resident, Maternal and Child Hospital of Vall Hebron (MCHVH), Autonomous University of Barcelona (www.vhebron.es), Barcelona, Spain
  • Resident in Obstetrics and Gynecology, Mayo Clinic Rochester, Rochester, Minnesota
  • Fellow in Mayo Cancer Genetic Epidemiology Training Program & Bioinformatics, Mayo Clinic, Rochester, Minnesota
  • Fellow in Gynecologic Oncology, Mayo Clinic, Rochester, Minnesota
  • Fellow in Bioinformatics & Translational Genomics, National Cancer Institute, National Institute of Health, Bethesda, Maryland

Graduate Program Affiliations

Research Interests

  • My research program at the University of Iowa is focused on investigating and creating scientifically valid methods to integrate biological ‘big data’ to predict clinical outcomes for gynecologic cancers.
  • Clinical research in Gynecologic Oncology:
  • Genetic association with cancer risk
  • Translational research in endometrial cancer:
  • Genomics and genetics in gynecologic cancers:
  • Genomic studies of association of chemo-response in ovarian cancer:
  • Molecular signature to predict chemo-response in serous ovarian cancer

Licenses & Certifications

  • Medical License, Iowa
  • Board Certified in Gynecologic Oncology, American Board of Obstetrics and Gynecology
  • Robotic-Assisted Surgery privileges
  • Board Certified in Obstetrics and Gynecology, American Board of Obstetrics and Gynecology
  • Board Certified in Obstetrics and Gynecology, Catalonian and Spanish Official College of Medicine, Barcelona, Spain

Selected Publications

  • Gonzalez Bosquet J, Polio A, George E, Tarhini AA, Cosgrove CM, Huang MS, Corr B, Leiser AL, Salhia B, Darcy K, Tarney CM, Dood RL, Dockery LE, Edge SB, Cavnar MJ, Landrum L, Rounbehler RJ, Churchman M, Wagner VM. Training, Validating, and Testing Machine Learning Prediction Models for Endometrial Cancer Recurrence. JCO Precis Oncol. 2025 May;9:e2400859. doi: 10.1200/PO-24-00859. Epub 2025 May 5. PMID: 40324114; PMCID: PMC12054588. https://pmc.ncbi.nlm.nih.gov/articles/PMC12054588/
  • Gonzalez-Bosquet J, Shahi M, Yadav S, Kanwar N, Alvand S, Sosa C, Dowdy SC, Halling KC, Weroha SJ, Bakkum-Gamez JN, Podratz KC. ECPPF stratification identifies occult high-risk subgroups in stage I, grade 1 or 2, ≤50 % invasive endometrial cancer: Candidates for adjuvant therapy. Gynecol Oncol. 2025 May;196:113-120. doi: 10.1016/j.ygyno.2025.03.030. Epub 2025 Apr 7. PMID: 40199195. https://www.sciencedirect.com/science/article/pii/S0090825825001076?via%3Dihub
  • Ulmer KK, Greteman B, Gonzalez Bosquet J, Petereit D, Harper D, Nash SH. Gynecological Cancers Among American Indian and Alaska Native Women Living in the Upper Midwest, 1995-2019. Womens Health Rep (New Rochelle). 2025 Feb 25;6(1):199-208. doi: 10.1089/whr.2024.0124. PMID: 40130037; PMCID: PMC11932641. https://www.liebertpub.com/doi/pdf/10.1089/whr.2024.0124
  • Gonzalez Bosquet J, Wagner V, Polio A, Linder KE, Bender DP, Goodheart MJ, Schickling BM. Identification of Ovarian High-Grade Serous Carcinoma with Mitochondrial Gene Variation. Int J Mol Sci. 2025 Feb 5;26(3):1347. doi: 10.3390/ijms26031347. PMID: 39941116; PMCID: PMC11818617. https://www.mdpi.com/1422-0067/26/3/1347
  • Roy T, Oliveira S, Ulmer K, Watson R, Gonzalez-Bosquet J, Wu X. Classification of ovarian carcinoma tissue or neoplasms. In Preparation. IEEE TRANSACTIONS ON MEDICAL IMAGING. 2022.
  • Watson R, Linder KE, Ulmer K, Gabrilovich S, McDonald M, Bender D, Goodheart M, Devor E, Gonzalez-Bosquet J. Prediction of ovarian cancer with deep machine-learning and alternative splicing. In Preparation. Gynecol Oncol 2022.
  • Gabrilovich S, Devor E, Ulmer K, Bender D, Goodheart M, Gonzalez-Bosquet J. scRNA-seq data can identify cell populations in bulk RNAseq specimens associated with optimal cytoreduction. In Preparation. Gynecol Oncol 2022.
  • Roy T, Oliveira S, Gonzalez-Bosquet J, Wu X. 3D Supervised Contrastive-Learning Network for Classification of Ovarian Neoplasms.  Medical Imaging with Deep Learning, short paper track 2023.
  • Gonzalez-Bosquet J, Weroha SJ, Bakkum-Gamez JN, Weaver AL, McGree ME, Dowdy SC, Famuyide AO, Kipp BR, Halling KC, Yadav S, Couch FJ, Podratz KC. Prognostic stratification of endometrial cancers with high microsatellite instability or no specific molecular profile. Front Oncol. 2023 May 23;13:1105504. doi: 10.3389/fonc.2023.1105504. PMID: 37287928; PMCID: PMC10242089.
  • Dixit G, Gonzalez-Bosquet J, Skurski J, Devor EJ, Dickerson EB, Nothnick WB, Issuree PD, Leslie KK, Maretzky T. FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways. Clin Transl Med. 2023 May;13(5):e1223. doi: 10.1002/ctm2.1223. PMID: 37165578; PMCID: PMC10172618. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172618/