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Malinda Schaefer, MD, PhD

Clinical Assistant Professor, Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine
Photo of Malinda Schaefer, MD, PhD
Malinda Schaefer, MD, PhD - University of Iowa
malinda-schaefer@uiowa.edu

Current Positions

  • Clinical Assistant Professor, Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine

Education

  • BS (Microbiology) – University of Wisconsin – La Crosse
  • PhD (Graduate Program in Immunology) – University of Michigan
  • Postdoctoral Fellowship – Emory University
  • MD (Medicine) – Medical College of Georgia
  • Resident (Obstetrics and Gynecology) – University of Minnesota
  • Fellow (Maternal-Fetal Medicine) – University of Pittsburgh Magee-Women’s Hospital, Pittsburgh, Pennsylvania

Research Interests

  • Research projects during fellowship
  • Research project during residency
  • Research project during postdoctoral fellowship
  • Thesis project for PhD

Selected Publications

  • Karita E, Nyombayire J, Ingabire R, Mazzei A, Sharkey T, Mukamuyango J, Allen S, Tichacek A, Parker R, Priddy F, Sayinzoga F, Nsanzimana S, Robinson C, Katwere M, Anumendem D, Leyssen M, Schaefer M, Wall KM. Safety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial. Trials. 2022 Jun 20;23(1):513. PMID: 35725488; PMCID: PMC9207821.https://doi.org/10.1186/s13063-022-06360-3
  • Schaefer MR, Williams M, Kulpa DA, Blakely PK, Yaffee AQ, Collins KL. A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages. J Immunol. 2008 Jun 15;180(12):7804-17. doi: 10.4049/jimmunol.180.12.7804. PMID: 18523244; PMCID: PMC2440697.
  • Schaefer MR, Wonderlich ER, Roeth JF, Leonard JA, Collins KL. HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells. PLoS Pathog. 2008 Aug 22;4(8):e1000131. doi: 10.1371/journal.ppat.1000131. PMID: 18725938; PMCID: PMC2515349.
  • Crawford H, Lumm W, Leslie A, Schaefer M, Boeras D, Prado JG, Tang J, Farmer P, Ndung'u T, Lakhi S, Gilmour J, Goepfert P, Walker BD, Kaslow R, Mulenga J, Allen S, Goulder PJ, Hunter E. Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients. J Exp Med. 2009 Apr 13;206(4):909-21. doi: 10.1084/jem.20081984. Epub 2009 Mar 23. PMID: 19307327; PMCID: PMC2715113.
  • Thammavongsa V, Schaefer M, Filzen T, Collins KL, Carrington M, Bangia N, Raghavan M. Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503. Immunogenetics. 2009 Dec;61(11-12):703-16. doi: 10.1007/s00251-009-0399-2. PMID: 19838694; PMCID: PMC2971690.
  • Bansal A, Carlson J, Yan J, Akinsiku OT, Schaefer M, Sabbaj S, Bet A, Levy DN, Heath S, Tang J, Kaslow RA, Walker BD, Ndung'u T, Goulder PJ, Heckerman D, Hunter E, Goepfert PA. CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription. J Exp Med. 2010 Jan 18;207(1):51-9. doi: 10.1084/jem.20092060. Epub 2010 Jan 11. PMID: 20065064; PMCID: PMC2812545.
  • Price MA, Wallis CL, Lakhi S, Karita E, Kamali A, Anzala O, Sanders EJ, Bekker LG, Twesigye R, Hunter E, Kaleebu P, Kayitenkore K, Allen S, Ruzagira E, Mwangome M, Mutua G, Amornkul PN, Stevens G, Pond SL, Schaefer M, Papathanasopoulos MA, Stevens W, Gilmour J; IAVI Early Infection Cohort Study Group. Transmitted HIV type 1 drug resistance among individuals with recent HIV infection in East and Southern Africa. AIDS Res Hum Retroviruses. 2011 Jan;27(1):5-12. doi: 10.1089/aid.2010.0030. Epub 2010 Nov 23. PMID: 21091377; PMCID: PMC3045073.
  • Crawford H, Matthews PC, Schaefer M, Carlson JM, Leslie A, Kilembe W, Allen S, Ndung'u T, Heckerman D, Hunter E, Goulder PJ. The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms. J Virol. 2011 Feb;85(3):1384-90. doi: 10.1128/JVI.01879-10. Epub 2010 Nov 24. PMID: 21106744; PMCID: PMC3020512.
  • Prince JL, Claiborne DT, Carlson JM, Schaefer M, Yu T, Lahki S, Prentice HA, Yue L, Vishwanathan SA, Kilembe W, Goepfert P, Price MA, Gilmour J, Mulenga J, Farmer P, Derdeyn CA, Tang J, Heckerman D, Kaslow RA, Allen SA, Hunter E. Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis. PLoS Pathog. 2012;8(11):e1003041. doi: 10.1371/journal.ppat.1003041. Epub 2012 Nov 29. PMID: 23209412; PMCID: PMC3510241.
  • Leonard JA, Filzen T, Carter CC, Schaefer M, Collins KL. HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elements. J Virol. 2011 Jul;85(14):6867-81. doi: 10.1128/JVI.00229-11. Epub 2011 May 4. PMID: 21543478; PMCID: PMC3126561.