Graduate Program Faculty

Cardiovascular/Renal:

  • Dao-Fu Dai, MD, PhD
    • Use of iPSC to model cardiomyopathies, mitochondrial signaling in cardiomyopathy, pathogenesis of glomerulonephritis

Immunology:

  • Vladimir Badovinac, PhD
    • Regulation of antigen-specific CD8 T cell memory and homeostasis after infection or vaccination
  • John Harty, PhD
    • T cell mediated resistance to pathogens
  • Nitin Karandikar, MD, PhD
    • Role of CD8 and CD4 T cells in the immune regulation of demyelinating diseases, multiple sclerosis, and experimental autoimmune encephalomyelitis
  • Kevin Legge, PhD
    • Dendritic cell immunobiology and pulmonary immunity
  • Ashutosh Mangalam, PhD
    • Role of T cells in multiple sclerosis, influence of gut microbiome on the pathogenesis of multiple sclerosis
  • Steven Varga, PhD
    • Viral immunology and immunopathology mediated by T cells
  • Thomas Waldschmidt, PhD
    • Role of B lymphocyte subsets in humoral immunity, germinal center biology, B cell responses to influenza virus and influenza vaccines
  • Jian Zhang, MD
    • Molecular mechanisms of T cell activation and differentiation, innate and adaptive immune responses regulated by E3 ubiquitin ligases Cbl-b and Nedd4

Microbiology:

  • Daniel Diekema, MD
    • Epidemiology and prevention of hospital-acquired fungal infections, surveillance of antifungal resistance

Neuroscience:

  • Marco Hefti, MD
    • Role of microtubules in neurologic outcomes of early-life hypoxic ischemic injury; aberrant splicing as a cause of cognitive dysfunction in myotonic dystrophy
  • Steven Moore, MD, PhD
    • Function of brain dystroglycan, genetic mouse models of muscular dystrophy
  • Stefan Strack, PhD
    • Role of phosphatases and mitochondrial fission in neuronal function and neurodegenerative disease

Tumor Biology and Cancer:

  • Adam Dupuy, PhD
    • Identification of tumor suppressor genes and oncogenes through insertional mutagenesis
  • Hasem Habelhah, PhD
    • Role of TRAF2 in oncogene- and stress- induced NF-κB activation and resistance to apoptosis in cancer cells
  • Michael Henry, PhD
    • Molecular basis of organ site-specific tumor metastasis
  • Bing-Hua Jiang, PhD
    • Role of signaling pathways, reactive oxygen species and microRNAs in angiogenesis, tumorigenesis and therapeutic resistance
  • Ling-Zhi Liu, MD, PhD
    • Mechanisms of arsenic and chromium induced carcinogenesis
  • Dawn Quelle, PhD
    • Molecular mechanisms of tumorigenesis, tumor suppressors and cell cycle control
  • Ann Simons-Burnett, PhD
    • Inflammation and oxidative stress in cancer progression and drug resistance
  • Douglas Spitz, PhD
    • Role of oxidative stress in cancer biology, toxicology and aging
  • Munir Tanas, MD
    • Mechanisms of aberrant transcriptional activation and its consequences in sarcoma
  • Weizhou Zhang, PhD
    • Role of inflammation in breast cancer initiation, progression and metastasis
  • Chen Zhao, MD, PhD
    • B cell leukemia/lymphoma initiating cells and their interactions with the microenvironment