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Recent Publications

Week of November 22, 2022
Further prognostic stratification of intestinal type of gastric adenocarcinoma by CDX2 expression pattern. Hao Y, Liu BL, Liang Y, Xiong Y, Polydorides AD, Ward S. Hum Pathol. 2022 Nov 17:S0046-8177(22)00262-3. doi: 10.1016/j.humpath.2022.11.005. Online ahead of print.

Refractory Pediatric Fibrostenotic Eosinophilic Esophagitis Treated With Dupilumab. Gangadharan Nambiar G, Rahhal R, Davis BP, Xiong Y, Cheung D. ACG Case Rep J. 2022 Nov 11;9(11):e00887. doi: 10.14309/crj.0000000000000887. eCollection 2022 Nov.

ASO Visual Abstract: Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms-A Systematic Review and Meta-Analysis. Ziogas IA, Tasoudis PT, Borbon LC, Sherman SK, Breheny PJ, Chandrasekharan C, Dillon JS, Bellizzi AM, Howe JR. Ann Surg Oncol. 2022 Nov 15. doi: 10.1245/s10434-022-12796-3. Online ahead of print.

SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways. Verma AK, Zheng J, Meyerholz DK, Perlman S. JCI Insight. 2022 Nov 15:e160277. doi: 10.1172/jci.insight.160277. Online ahead of print.


Week of November 15, 2022
Propofol-induced interference with activated partial thromboplastin time-based monitoring of therapeutic heparin anticoagulation. Negaard BJ, Hobbs R, Frye JR, Merrill AE. Am J Health Syst Pharm. 2022 Nov 12:zxac337. doi: 10.1093/ajhp/zxac337. Online ahead of print.

Keeping T cell memories in mind. Mix MR, Harty JT. Trends Immunol. 2022 Nov 8:S1471-4906(22)00209-5. doi: 10.1016/j.it.2022.10.001. Online ahead of print.


Week of November 8, 2022
Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy. Allen BD, Alaghband Y, Kramár EA, Ru N, Petit B, Grilj V, Petronek MS, Pulliam CF, Kim RY, Doan NL, Baulch JE, Wood MA, Bailat C, Spitz DR, Vozenin MC, Limoli CL. Neuro Oncol. 2022 Nov 5:noac248. doi: 10.1093/neuonc/noac248. Online ahead of print.

Endogenous SOD2 (Superoxide Dismutase) Regulates Platelet-Dependent Thrombin Generation and Thrombosis During Aging. Sonkar VK, Eustes AS, Ahmed A, Jensen M, Solanki MV, Swamy J, Kumar R, Fidler TP, Houtman JCD, Allen BG, Spitz DR, Abel ED, Dayal S. Arterioscler Thromb Vasc Biol. 2022 Nov 3. doi: 10.1161/ATVBAHA.121.317735. Online ahead of print.

Complex Sweat Gland Hamartoma: A Case Report. Skopec Z, Berrebi K, Stone M, Liu V. J Cutan Pathol. 2022 Nov 2. doi: 10.1111/cup.14350. Online ahead of print.


Week of November 1, 2022
Long-Lasting Protection Induced by a Polyanhydride Nanovaccine against Respiratory Syncytial Virus in an Outbred Mouse Model. Stephens LM, Ross KA, McLellan JS, Narasimhan B, Varga SM. J Virol. 2022 Oct 31:e0150222. doi: 10.1128/jvi.01502-22. Online ahead of print.

Rates of Antimicrobial Resistance With Extended Oral Antibiotic Prophylaxis After Total Joint Arthroplasty. Carender CN, Sekar P, Prasidthrathsint K, DeMik DE, Brown TS, Bedard NA. Arthroplast Today. 2022 Oct 25;18:112-118. doi: 10.1016/j.artd.2022.09.007. eCollection 2022 Dec.

A Case of Secondary Hemophagocytic Lymphohistiocytosis Presenting with Severe Dyserythropoeisis in a Patient with Autoimmune Hemolysis. Rogers KJ, Bhagavathi S. Case Rep Hematol. 2022 Oct 19;2022:8505823. doi: 10.1155/2022/8505823. eCollection 2022.

A live single-cycle RSV vaccine expressing prefusion F protein. Lamichhane P, Schmidt ME, Terhüja M, Varga SM, Snider TA, Rostad CA, Oomens AGP. Virology. 2022 Oct 15;577:51-64. doi: 10.1016/j.virol.2022.10.003. Online ahead of print.

Isoflavone consumption reduces inflammation through modulation of phenylalanine and lipid metabolism. Shrode RL, Cady N, Jensen SN, Borcherding N, Mangalam AK. Metabolomics. 2022 Oct 26;18(11):84. doi: 10.1007/s11306-022-01944-1.

Activities of Manogepix and Comparators against 1,435 Recent Fungal Isolates Collected during an International Surveillance Program (2020). Pfaller MA, Huband MD, Rhomberg PR, Bien PA, Castanheira M. Antimicrob Agents Chemother. 2022 Oct 26:e0102822. doi: 10.1128/aac.01028-22. Online ahead of print.

Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat. Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Mol Cell Biochem. 2022 Oct 25. doi: 10.1007/s11010-022-04589-9. Online ahead of print.

TRAF3IP2-IL-17 Axis Strengthens the Gingival Defense against Pathogens. Zhang J, Sun L, Withanage MHH, Ganesan SM, Williamson MA, Marchesan JT, Jiao Y, Teles FR, Yu N, Liu Y, Wu D, Moss KL, Mangalam AK, Zeng E, Lei YL, Zhang S. J Dent Res. 2022 Oct 24:220345221123256. doi: 10.1177/00220345221123256. Online ahead of print.


Week of October 25, 2022
Use of compressed sensing to expedite high-throughput diagnostic testing for COVID-19 and beyond. Waldstein KA, Yi J, Cho M, Mudumbai R, Wu X, Varga SM, Xu W. PLoS Comput Biol. 2022 Oct 24;18(10):e1010629. doi: 10.1371/journal.pcbi.1010629. Online ahead of print.

Tissue resident memory T cells- A new benchmark for the induction of vaccine-induced mucosal immunity. Hassert M, Harty JT. Front Immunol. 2022 Oct 4;13:1039194. doi: 10.3389/fimmu.2022.1039194. eCollection 2022.

SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. NPJ Precis Oncol. 2022 Oct 21;6(1):74. doi: 10.1038/s41698-022-00310-7.

Plasticity of Cerebral Microvascular Structure and Mechanics During Hypertension and Following Recovery of Arterial Pressure. Sabharwal R, Chapleau MW, Gerhold TD, Baumbach GL, Faraci FM. Am J Physiol Heart Circ Physiol. 2022 Oct 21. doi: 10.1152/ajpheart.00292.2022. Online ahead of print.

Anatomic pathology quality assurance: Developing an LIS based tracking and documentation module for intradepartmental consultations. Dundar B, Chen SJ, Blau JL, Anand Rajan KD, Samuelson MI, Greek-Lippe ML, Lake KS, Robinson RA. J Pathol Inform. 2022 Jun 24;13:100109. doi: 10.1016/j.jpi.2022.100109. eCollection 2022.

The genome-wide DNA methylation profiles among neurosurgery patients with and without post-operative delirium. Yamanashi T, Crutchley KJ, Wahba NE, Nagao T, Marra PS, Akers CC, Sullivan EJ, Iwata M, Howard MA 3rd, Cho HR, Kawasaki H, Hughes CG, Pandharipande PP, Hefti MM, Shinozaki G. Psychiatry Clin Neurosci. 2022 Oct 20. doi: 10.1111/pcn.13495. Online ahead of print.

Delays in melanoma presentation during the COVID-19 pandemic: A nationwide multi-institutional cohort study. Trepanowski N, Chang MS, Zhou G, Ahmad M, Berry EG, Bui K, Butler WH, Chu EY, Curiel-Lewandrowski C, Dellalana LE, Ellis DL, Freeman SC, Gorrepati PL, Grossman D, Gyurdzhyan S, Kanetsky PA, Ong King AL, Kolla AM, Lian CG, Lin JY, Liu V, Lowenthal A, McCoy KN, Munjal A, Myrdal CN, Perkins S, Powers JG, Rauck C, Smart TC, Stein JA, Venna S, Walsh ME, Wang JY, Leachman SA, Swetter SM, Hartman RI. J Am Acad Dermatol. 2022 Nov;87(5):1217-1219. doi: 10.1016/j.jaad.2022.06.031. Epub 2022 Jun 20.


Week of October 18, 2022
Biobehavioral factors predict an exosome biomarker of ovarian carcinoma disease progression. Lutgendorf SK, Thaker PH, Goodheart MJ, Arevalo JMG, Chowdhury MA, Noble AE, Dahmoush L, Slavich GM, Penedo FJ, Sood AK, Cole SW. Cancer. 2022 Oct 17. doi: 10.1002/cncr.34496. Online ahead of print.

A thorny matter: spur cell anemia. Sharma R, Holman CJ, Brown KE. Ann Hepatol. 2022 Oct 11:100771. doi: 10.1016/j.aohep.2022.100771. Online ahead of print.

Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. Li Y, Zhou W, Meng X, Murray SD, Li L, Fronk A, Lazaro-Camp VJ, Wen KK, Wu M, Dupuy A, Leslie KK, Yang S. Cancers (Basel). 2022 Oct 6;14(19):4883. doi: 10.3390/cancers14194883.

Manipulation of Redox Metabolism using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-sensitization by ATM Inhibitors in Colorectal Cancer. Callaghan CM, Abukhiran IM, Masaadeh A, Van Rheeden RV, Kalen AL, Rodman SN 3rd, Petronek MS, Mapuskar KA, George BN, Coleman MC, Goswami PC, Allen BG, Spitz DR, Caster JM. Int J Radiat Oncol Biol Phys. 2022 Oct 10:S0360-3016(22)03438-1. doi: 10.1016/j.ijrobp.2022.10.012. Online ahead of print.

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism. Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. Online ahead of print.

Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review and Meta-analysis. Ziogas IA, Tasoudis PT, Borbon LC, Sherman SK, Breheny PJ, Chandrasekharan C, Dillon JS, Bellizzi AM, Howe JR. Ann Surg Oncol. 2022 Oct 13. doi: 10.1245/s10434-022-12643-5. Online ahead of print.

Nicotine and Tobacco Alkaloid Testing and Challenges. Snozek CLH, McMillin GA, Nwosu A, Dizon A, Krasowski MD. Arch Pathol Lab Med. 2022 Oct 10. doi: 10.5858/arpa.2022-0094-CP. Online ahead of print.

Influenza-Induced CD103+ T Resident Memory Cells Exhibit Enhanced Functional Avidity over CD103- Memory T Cells in the Mediastinal Lymph Node. Crooks SD, Varga SM, Harty JT. Immunohorizons. 2022 Oct 11;6(10):705-715. doi: 10.4049/immunohorizons.2100074.

Evaluation of the Post-Antifungal Effect of Rezafungin and Micafungin against Candida albicans, Candida parapsilosis and Candida glabrata. Carvalhaes CG, Rhomberg PR, Pfaller MA, Locke JB, Castanheira M. Mycoses. 2022 Nov;65(11):1040-1044. doi: 10.1111/myc.13490. Epub 2022 Jul 18.


Week of October 11, 2022
Distribution of High-Sensitivity Cardiac Troponin and N-Terminal Pro-Brain Natriuretic Peptide in Healthy Transgender People. Greene DN, Schmidt RL, Christenson RH, Rongitsch J, Imborek KL, Rebuck H, Lorey TS, Saenger AK, Krasowski MD. JAMA Cardiol. 2022 Oct 5. doi: 10.1001/jamacardio.2022.3299. Online ahead of print.

Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of Staphylococcus aureus Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention. Suzuki H, Goto M, Nair R, Livorsi DJ, Sekar P, Ohl ME, Diekema DJ, Perencevich EN, Alexander B, Jones MP, McDaniel JS, Schweizer ML. Open Forum Infect Dis. 2022 Sep 12;9(9):ofac473. doi: 10.1093/ofid/ofac473. eCollection 2022 Sep.

Clinical Decision Support Systems to Reduce Unnecessary Clostridioides difficile Testing Across Multiple Hospitals. Rock C, Abosi O, Bleasdale S, Colligan E, Diekema DJ, Dullabh P, Gurses AP, Heaney-Huls K, Jacob JT, Kandiah S, Lama S, Leekha S, Mayer J, Mena Lora AJ, Morgan DJ, Osei P, Pau S, Salinas JL, Spivak E, Wenzler E, Cosgrove SE. Clin Infect Dis. 2022 Sep 30;75(7):1187-1193. doi: 10.1093/cid/ciac074.


Week of October 4, 2022
Cbl-b restrains priming of pathogenic Th17 cells via the inhibition of IL-6 production by macrophages. Zeng Q, Tang N, Ma Y, Guo H, Zhao Y, Tang R, Yan C, Ouyang S, Langdon WY, Yang H, O'Brien MC, Zhang J. iScience. 2022 Sep 15;25(10):105151. doi: 10.1016/j.isci.2022.105151. eCollection 2022 Oct 21.

Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation. Ghimire S, Cady NM, Lehman P, Peterson SR, Shahi SK, Rashid F, Giri S, Mangalam AK. Gut Microbes. 2022 Jan-Dec;14(1):2127446. doi: 10.1080/19490976.2022.2127446.

Orf Virus in Humans: Case Series and Clinical Review. Thompson HJ, Harview CL, Swick B, Powers JG. Cutis. 2022 Jul;110(1):48-52. doi: 10.12788/cutis.0567.

TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies. Basisty N, Shulman N, Wehrfritz C, Marsh AN, Shah S, Rose J, Ebert S, Miller M, Dai DF, Rabinovitch PS, Adams CM, MacCoss MJ, MacLean B, Schilling B. J Proteome Res. 2022 Sep 27. doi: 10.1021/acs.jproteome.2c00173. Online ahead of print.

Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis. Shahi SK, Ghimire S, Lehman P, Mangalam AK. Front Immunol. 2022 Sep 9;13:966417. doi: 10.3389/fimmu.2022.966417. eCollection 2022.


Week of September 27, 2022
Multicenter Collaborative Study of the Interaction of Antifungal Combinations against Candida Spp. by Loewe Additivity and Bliss Independence-Based Response Surface Analysis. Meletiadis J, Andes DR, Lockhart SR, Ghannoum MA, Knapp CC, Ostrosky-Zeichner L, Pfaller MA, Chaturvedi V, Walsh TJ. J Fungi (Basel). 2022 Sep 16;8(9):967. doi: 10.3390/jof8090967.

Congenital Neutropenia with Specific Granulocyte Deficiency Caused by Novel Double Heterozygous SMARCD2 Mutations. Ibrahim A, Sharathkumar A, McLaughlin H, Claassen D, Bhagavathi S. Hematol Rep. 2022 Sep 9;14(3):270-275. doi: 10.3390/hematolrep14030038.

Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis. Huang L, Ma Y, Guo H, Tang N, Ouyang S, Nuro-Gyina P, Tao L, Liu Y, O'Brien MC, Langdon WY, Zhang J. J Immunol. 2022 Sep 1;209(5):991-1000. doi: 10.4049/jimmunol.2101003. Epub 2022 Aug 5.


Week of September 20, 2022
SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. El-Kafrawy SA, Odle A, Abbas AT, Hassan AM, Abdel-Dayem UA, Qureshi AK, Wong LR, Zheng J, Meyerholz DK, Perlman S, Zumla A, Azhar EI. PLoS Pathog. 2022 Sep 19;18(9):e1010782. doi: 10.1371/journal.ppat.1010782. eCollection 2022 Sep.

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Vaishnavi A, Juan J, Jacob M, Stehn C, Gardner EE, Scherzer MT, Schuman S, van Veen JE, Murphy B, Hackett CS, Dupuy AJ, Chmura SA, van der Weyden L, Newberg JY, Liu A, Mann K, Rust AG, Weiss WA, Kinsey CG, Adams DJ, Grossmann A, Mann MB, McMahon M. Cancer Res. 2022 Sep 16:CAN-21-3214. doi: 10.1158/0008-5472.CAN-21-3214. Online ahead of print.

Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment. Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, Tinkum KL, Gass H, Nunez E, Spitz DR, Chinnaiyan P, Schaefer J, Patti GJ, Graham MS, Mauguen A, Grkovski M, Dunphy MP, Krebs S, Luo J, Rubin JB, Ippolito JE. Med (N Y). 2022 Sep 8:S2666-6340(22)00365-8. doi: 10.1016/j.medj.2022.08.005. Online ahead of print.

Evolving mucocutaneous eruptions following chemotherapy. Chen A, Patrick AP, Sharif-Sidi Z, Liu V, Fairley JA. JAAD Case Rep. 2022 Aug 10;28:67-70. doi: 10.1016/j.jdcr.2022.08.004. eCollection 2022 Oct.

Metastatic extraskeletal myxoid chondrosarcoma presenting as a forehead mass. Tan KW, Jamison AS, Swick BL, Ferguson NN. JAAD Case Rep. 2022 Aug 11;28:40-43. doi: 10.1016/j.jdcr.2022.08.012. eCollection 2022 Oct.

Days of Antibiotic Spectrum Coverage: A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2022 Sep 10;75(4):567-576. doi: 10.1093/cid/ciab1034.


Week of September 13, 2022
TAZ/YAP fusion proteins: mechanistic insights and therapeutic opportunities. Garcia K, Gingras AC, Harvey KF, Tanas MR. Trends Cancer. 2022 Sep 9:S2405-8033(22)00173-X. doi: 10.1016/j.trecan.2022.08.002. Online ahead of print.

Pharmacological ascorbate as a novel therapeutic strategy to enhance cancer immunotherapy. Zaher A, Stephens LM, Miller AM, Hartwig SM, Stolwijk JM, Petronek MS, Zacharias ZR, Wadas TJ, Monga V, Cullen JJ, Furqan M, Houtman JCD, Varga SM, Spitz DR, Allen BG. Front Immunol. 2022 Aug 22;13:989000. doi: 10.3389/fimmu.2022.989000. eCollection 2022.

PRC2 loss drives MPNST metastasis and matrix remodeling. Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. JCI Insight. 2022 Sep 6:e157502. doi: 10.1172/jci.insight.157502. Online ahead of print.

Causes of death in low-grade B-cell lymphomas in the rituximab era: a prospective cohort study. Tun AM, Khurana A, Mwangi R, Link BK, Wang Y, Feldman AL, Thompson CA, Novak AJ, Villasboas JC, Thanarajasingam G, Farooq U, Syrbu S, Nowakowski GS, Witzig TE, Ansell SM, Rimsza LM, Cerhan JR, Habermann TM, Maurer MJ. Blood Adv. 2022 Sep 13;6(17):5210-5221. doi: 10.1182/bloodadvances.2022007990.


Week of September 6, 2022
Isolated MLH1 Loss by Immunohistochemistry Because of Benign Germline MLH1 Polymorphisms. Bosch DE, Yeh MM, Salipante SJ, Jacobson A, Cohen SA, Konnick EQ, Paulson VA. JCO Precis Oncol. 2022 Aug;6:e2200227. doi: 10.1200/PO.22.00227.

Optimal Urine Culture Diagnostic Stewardship Practice-Results from an Expert Modified-Delphi Procedure. Claeys KC, Trautner BW, Leekha S, Coffey KC, Crnich CJ, Diekema DJ, Fakih MG, Goetz MB, Gupta K, Jones MM, Leykum L, Liang SY, Pineles L, Pleiss A, Spivak ES, Suda KJ, Taylor JM, Rhee C, Morgan DJ. Clin Infect Dis. 2022 Aug 31;75(3):382-389. doi: 10.1093/cid/ciab987.


Week of August 23, 2022
Activity of Ceftolozane-Tazobactam Against Gram-Negative Isolates from Australia and New Zealand as part of the PACTS Surveillance 2016-2018. Shortridge D, Streit J, Pfaller M, Tulloch M, Chen WT, Castanheira M. J Glob Antimicrob Resist. 2022 Aug 18:S2213-7165(22)00200-4. doi: 10.1016/j.jgar.2022.08.009. Online ahead of print.

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation. Wei L, Wang W, Yao J, Cui Z, Xu Z, Ding H, Wu X, Wang D, Luo J, Ke ZJ. Oncogene. 2022 Aug 16. doi: 10.1038/s41388-022-02431-6. Online ahead of print.


Week of August 16, 2022
Negative regulation of receptor tyrosine kinases by ubiquitination: Key roles of the Cbl family of E3 ubiquitin ligases. Tang R, Langdon WY, Zhang J. Front Endocrinol (Lausanne). 2022 Jul 28;13:971162. doi: 10.3389/fendo.2022.971162. eCollection 2022.

Prognostic Role of Combined EGFR and Tumor-Infiltrating Lymphocytes in Oral Squamous Cell Carcinoma. Wongpattaraworakul W, Gibson-Corley KN, Choi A, Buchakjian MR, Lanzel EA, Rajan Kd A, Simons AL. Front Oncol. 2022 Jul 25;12:885236. doi: 10.3389/fonc.2022.885236. eCollection 2022.

ERBB2 (HER2) Alterations in Colorectal Cancer. Roy-Chowdhuri S, Davies KD, Ritterhouse LL, Snow AN. J Mol Diagn. 2022 Aug 6:S1525-1578(22)00196-9. doi: 10.1016/j.jmoldx.2022.07.001. Online ahead of print.


Week of August 9, 2022
Lung allograft standardized histological analysis (LASHA) template: A research consensus proposal. Calabrese F, Roden AC, Pavlisko E, Lunardi F, Neil D, Adam B, Hwang D, Goddard M, Berry GJ, Ivanovic M, Thüsen JV, Gibault L, Lin CY, Wassilew K, Glass C, Westall G, Zeevi A, Levine DJ, Roux A. J Heart Lung Transplant. 2022 Jul 3:S1053-2498(22)02019-8. doi: 10.1016/j.healun.2022.06.021. Online ahead of print.

Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition. Li Y, Balakrishnan VK, Rowse M, Wu CG, Bravos AP, Yadav VK, Ivarsson Y, Strack S, Novikova IV, Xing Y. Elife. 2022 Aug 4;11:e79736. doi: 10.7554/eLife.79736. Online ahead of print.

Coronavirus disease 2019 (COVID-19) admission screening and assessment of infectiousness at an academic medical center in Iowa, 2020. Alsuhaibani MA, Kobayashi T, Trannel A, Holley S, Abosi OJ, Jenn KE, Meacham H, Sheeler L, Etienne W, Dains A, Kukla ME, Ward E, Ford B, Edmond MB, Wellington M, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2022 Aug;43(8):974-978. doi: 10.1017/ice.2021.294. Epub 2021 Jun 24.


Week of August 2, 2022
Oxidative stress and impaired insulin secretion in cystic fibrosis pig pancreas. O'Malley Y, Coleman MC, Sun X, Lei J, Yao J, Pulliam CF, Kluz P, McCormick ML, Yi Y, Imai Y, Engelhardt JF, Norris AW, Spitz DR, Uc A. Adv Redox Res. 2022 Jul;5:100040. doi: 10.1016/j.arres.2022.100040. Epub 2022 Jun 9.

Monogenic focal segmental glomerulosclerosis: A conceptual framework for identification and management of a heterogeneous disease. Sambharia M, Rastogi P, Thomas CP. Am J Med Genet C Semin Med Genet. 2022 Jul 27. doi: 10.1002/ajmg.c.31990. Online ahead of print.

Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice. De la Garza-Rodea AS, Moore SA, Zamora-Pineda J, Hoffman EP, Mistry K, Kumar A, Strober JB, Zhao P, Suh JH, Saba JD. Int J Mol Sci. 2022 Jul 8;23(14):7579. doi: 10.3390/ijms23147579.

CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation. Gai D, Chen JR, Stewart JP, Nookaew I, Habelhah H, Ashby C, Sun F, Cheng Y, Li C, Xu H, Peng B, Garg TK, Schinke C, Thanendrarajan S, Zangari M, Chen F, Barlogie B, van Rhee F, Tricot G, Shaughnessy JD Jr, Zhan F. J Clin Invest. 2022 Jul 26:e159527. doi: 10.1172/JCI159527. Online ahead of print.


Week of July 26, 2022
Inflammation Controls Susceptibility of Immune-Experienced Mice to Sepsis. Berton RR, Jensen IJ, Harty JT, Griffith TS, Badovinac VP. Immunohorizons. 2022 Jul 25;6(7):528-542. doi: 10.4049/immunohorizons.2200050.

Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndrome. Yoon JY, Daneshgar N, Chu Y, Chen B, Hefti M, Vikram A, Irani K, Song LS, Brenner C, Abel ED, London B, Dai DF. Clin Transl Med. 2022 Jul;12(7):e954. doi: 10.1002/ctm2.954.

Plasma Neurofilament Light and Glial Fibrillary Acidic Protein Levels over Thirty Days in a Porcine Model of Traumatic Brain Injury. Shin SS, Hefti MM, Mazandi VM, Issadore DA, Meaney DF, Schneider ALC, Diaz-Arrastia R, Kilbaugh TJ. J Neurotrauma. 2022 Jul;39(13-14):935-943. doi: 10.1089/neu.2022.0070.


Week of July 19, 2022
Causes of Death in Low Grade B-Cell Lymphomas in the Rituximab Era: A Prospective Cohort Study. Tun A, Khurana A, Mwangi R, Link BK, Wang Y, Feldman A, Thompson CA, Novak AJ, Villasboas JC, Thanarajasingam G, Farooq U, Syrbu SI, Nowakowski GS, Witzig TE, Ansell SM, Rimsza LM, Cerhan JR, Habermann TM, Maurer MJ. Blood Adv. 2022 Jul 18:bloodadvances.2022007990. doi: 10.1182/bloodadvances.2022007990. Online ahead of print.

ASO Visual Abstract: Is There a Role for Surgical Resection of Grade 3 Neuroendocrine Neoplasms? Borbon LC, Tran CG, Sherman SK, Ear PH, Chandrasekharan C, Bellizzi AM, Dillon JS, O'Dorisio TM, Howe JR. Ann Surg Oncol. 2022 Jul 18. doi: 10.1245/s10434-022-12229-1. Online ahead of print.

Gene Expression Signatures for the Accurate Diagnosis of Peripheral T-Cell Lymphoma Entities in the Routine Clinical Practice. Amador C, Bouska A, Wright G, Weisenburger DD, Feldman AL, Greiner TC, Lone W, Heavican T, Smith L, Pileri S, Tabanelli V, Ott G, Rosenwald A, Savage KJ, Slack G, Kim WS, Hyeh Y, Li Y, Dong G, Song J, Ondrejka S, Cook JR, Barrionuevo C, Lim ST, Ong CK, Chapman J, Inghirami G, Raess PW, Bhagavathi S, Gould C, Blombery P, Jaffe E, Morris SW, Rimsza LM, Vose JM, Staudt L, Chan WC, Iqbal J. J Clin Oncol. 2022 Jul 15:JCO2102707. doi: 10.1200/JCO.21.02707. Online ahead of print.

Patient ABO blood type is a major predictor of a positive DAT following a transfusion reaction. Schnieders E, Leon J, Chapman JM, Knudson CM. Transfusion. 2022 Jul 14. doi: 10.1111/trf.17019. Online ahead of print.


Week of July 12, 2022
Larotrectinib in Mismatch-Repair-Deficient TRK Fusion-Positive Metastatic Colon Cancer After Progression on Immunotherapy. Kasi PM, Afghan MK, Bellizzi AM, Chan CH. Cureus. 2022 Jul 7;14(7):e26648. doi: 10.7759/cureus.26648. eCollection 2022 Jul.

Is There a Role for Surgical Resection of Grade 3 Neuroendocrine Neoplasms? Borbon LC, Tran CG, Sherman SK, Ear PH, Chandrasekharan C, Bellizzi AM, Dillon JS, O'Dorisio TM, Howe JR. Ann Surg Oncol. 2022 Jul 8. doi: 10.1245/s10434-022-12100-3. Online ahead of print.

Prevalence of pelvic floor disorders in adult women being seen in a primary care setting and associated risk factors. Kenne K, Wendt L, Jackson JB. Scientific Reports. 2022: 12:9878 doi: 10.1038/s41598-022-13501-w.


Week of July 5, 2022
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M. Cell. 2022 Jun 13:S0092-8674(22)00713-9. doi: 10.1016/j.cell.2022.06.008. Online ahead of print.

Delivery of therapeutic carbon monoxide by gas-entrapping materials. Byrne JD, Gallo D, Boyce H, Becker SL, Kezar KM, Cotoia AT, Feig VR, Lopes A, Csizmadia E, Longhi MS, Lee JS, Kim H, Wentworth AJ, Shankar S, Lee GR, Bi J, Witt E, Ishida K, Hayward A, Kuosmanen JLP, Jenkins J, Wainer J, Aragon A, Wong K, Steiger C, Jeck WR, Bosch DE, Coleman MC, Spitz DR, Tift M, Langer R, Otterbein LE, Traverso G. Sci Transl Med. 2022 Jun 29;14(651):eabl4135. doi: 10.1126/scitranslmed.abl4135. Epub 2022 Jun 29.

Research Relevant Background Lesions and Conditions: Ferrets, Dogs, Swine, Sheep, and Goats. Helke KL, Meyerholz DK, Beck AP, Burrough ER, Derscheid RJ, Löhr C, McInnes EF, Scudamore CL, Brayton CF. ILAR J. 2021 Dec 31;62(1-2):133-168. doi: 10.1093/ilar/ilab005.


Week of June 28, 2022
Data on the clinical, analytical, and laboratory factors associated with negative anion gaps at an academic medical center. Laakman JM, Fleishhacker ZJ, Krasowski MD. Data Brief. 2022 Jun 6;43:108357. doi: 10.1016/j.dib.2022.108357. eCollection 2022 Aug.

Ethanol Exposure Up-Regulates PD-L1/PD-1 Immune Checkpoint Pathway and Promotes Mammary Tumor Development. Xu W, Wu L, Xu M, Luo J, Chen G. Front Oncol. 2022 Jun 8;12:874156. doi: 10.3389/fonc.2022.874156. eCollection 2022.

Utility of CD138/syndecan-1 immunohistochemistry for localization of plasmacytes is tissue-dependent in B6 mice. Meyerholz DK, Leidinger MR, Goeken JA, Businga TR, Akers A, Vizuett S, Kaemmer CA, Kohlmeyer JL, Dodd RD, Quelle DE. BMC Res Notes. 2022 Jun 25;15(1):219. doi: 10.1186/s13104-022-06100-5.

Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion and prominent epidermal involvement: A case report. Vest BE, Harview CL, Liu V, Swick BL, Berrebi KG, Olivares S, Stone MS, Sargen MR, Gerami P. J Cutan Pathol. 2022 Jun 25. doi: 10.1111/cup.14287. Online ahead of print.

Delays in melanoma presentation during the COVID-19 pandemic: a nationwide multi-institutional cohort study. Trepanowski N, Chang MS, Zhou G, Ahmad M, Berry EG, Bui K, Butler WH, Chu EY, Curiel-Lewandrowski C, Dellalana LE, Ellis DL, Freeman SC, Gorrepati PL, Grossman D, Gyurdzhyan S, Kanetsky PA, Loren Ong King A, Kolla AM, Lian CG, Lin JY, Liu V, Lowenthal A, McCoy KN, Munjal A, Myrdal CN, Perkins S, Powers JG, Rauck C, Smart TC, Stein JA, Venna S, Walsh ME, Wang JY, Leachman SA, Swetter SM, Hartman RI. J Am Acad Dermatol. 2022 Jun 20:S0190-9622(22)01023-4. doi: 10.1016/j.jaad.2022.06.031. Online ahead of print.

Self-activating G protein α subunits engage seven-transmembrane Regulator of G protein Signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri. Bosch DE, Jeck WR, Siderovski DP. J Biol Chem. 2022 Jun 20:102167. doi: 10.1016/j.jbc.2022.102167. Online ahead of print.

Special focus on SARS-CoV-2 and other zoonotic respiratory coronaviruses in animal models. Adissu HA, Meyerholz DK, Martinot AJ, Ward JM. Vet Pathol. 2022 Jul;59(4):513-515. doi: 10.1177/03009858221096502.

Azole resistance in Candida glabrata clinical isolates from global surveillance is associated with efflux overexpression. Castanheira M, Deshpande LM, Davis AP, Carvalhaes CG, Pfaller MA. J Glob Antimicrob Resist. 2022 Jun;29:371-377. doi: 10.1016/j.jgar.2022.05.004. Epub 2022 May 14.


Week of June 21, 2022
Mice expressing P301S mutant human tau have deficits in interval timing. Larson T, Khandelwal V, Weber MA, Leidinger MR, Meyerholz DK, Narayanan NS, Zhang Q. Behav Brain Res. 2022 Jun 16:113967. doi: 10.1016/j.bbr.2022.113967. Online ahead of print.

Special focus on SARS-CoV-2 and other zoonotic respiratory coronaviruses in animal models. Adissu HA, Meyerholz DK, Martinot AJ, Ward JM. Vet Pathol. 2022 Jul;59(4):513-515. doi: 10.1177/03009858221096502.

The Genetics of Early-Stage Melanoma in a Veteran Population. Cheung K, Bossler AD, Mott SL, Zeisler M, McKillip J, Zakharia Y, Swick BL, Powers JG. Front Oncol. 2022 May 30;12:887768. doi: 10.3389/fonc.2022.887768. eCollection 2022.

An 18-month-old with white matter calcifications and seizures. Fiock KL, Lin LC, Colwell S, Hefti MM. Brain Pathol. 2022 Jun 14. doi: 10.1111/bpa.13082. Online ahead of print.

Effectiveness and acceptability of intranasal povidone-iodine decolonization among fracture fixation surgery patients to reduce Staphylococcus aureus nasal colonization. Schweizer ML, Herwaldt LA, Boyken L, Pottinger J, Quinn R, Diekema DJ, Armstrong-Pavlik F, Ward M, Sekar P, Willey MC. Infect Control Hosp Epidemiol. 2022 Jun 15:1-3. doi: 10.1017/ice.2022.134. Online ahead of print.

Blood-based untargeted metabolomics in relapsing-remitting multiple sclerosis revealed the testable therapeutic target. Zahoor I, Suhail H, Datta I, Ahmed ME, Poisson LM, Waters J, Rashid F, Bin R, Singh J, Cerghet M, Kumar A, Hoda MN, Rattan R, Mangalam AK, Giri S. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2123265119. doi: 10.1073/pnas.2123265119. Epub 2022 Jun 14.


Week of June 14, 2022
Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model. Areecheewakul S, Adamcakova-Dodd A, Haque E, Jing X, Meyerholz DK, O'Shaughnessy PT, Thorne PS, Salem AK. Part Fibre Toxicol. 2022 Jun 13;19(1):40. doi: 10.1186/s12989-022-00480-z.


Week of June 7, 2022
TP53 Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study. Thiel KW, Devor EJ, Filiaci VL, Mutch D, Moxley K, Alvarez Secord A, Tewari KS, McDonald ME, Mathews C, Cosgrove C, Dewdney S, Aghajanian C, Samuelson MI, Lankes HA, Soslow RA, Leslie KK. J Clin Oncol. 2022 Jun 3:JCO2102506. doi: 10.1200/JCO.21.02506. Online ahead of print.

Assessment of Polychlorinated Biphenyls and Their Hydroxylated Metabolites in Postmortem Human Brain Samples: Age and Brain Region Differences. Li X, Hefti MM, Marek RF, Hornbuckle KC, Wang K, Lehmler HJ. Environ Sci Technol. 2022 Jun 3. doi: 10.1021/acs.est.2c00581. Online ahead of print.

Coronavirus Disease-2019 (COVID-19) among Non-physician Healthcare Personnel by Work Location at a Tertiary Care Center, Iowa, 2020-2021. Kobayashi T, Heinemann J, Trannel A, Marra AR, Alsuhaibani M, Etienne W, Sheeler LL, Abosi O, Holley S, Kukla MB, Dains A, Jenn KE, Meacham H, Hanna B, Ford B, Brust K, Wellington M, Hartley PG, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2022 Jun 2:1-11. doi: 10.1017/ice.2022.148. Online ahead of print.

Pain, Pain, Go Away: Exploring the Role of the Immune System in Regulating Chronic Pain. Rogers KJ, Merrill AE. Clin Chem. 2022 Jun 1;68(6):863. doi: 10.1093/clinchem/hvac013.

Outflow graft foreign body reaction and thrombosis in HeartMate 3 left ventricular assist device. Alvarez, P., Humble, R., Firchau, D., & Briasoulis, A. Asian Cardiovasc Thorac Ann. 2021;2184923211031343. doi:10.1177/02184923211031343

Temporal changes in medical student perceptions of their clinical skills and needs using a repeated self-assessment instrument. Barlow P, Humble R, Shibli-Rahhal A. BMC Med Educ. 2021;21(1):550. Published 2021 Oct 29. doi:10.1186/s12909-021-02985-1


Week of May 24, 2022
Ceftobiprole activity against Gram-positive and Gram-negative pathogens causing bone and joint infections in the United States from 2016 to 2020. Duncan LR, Hamed KA, Smart JI, Pfaller MA, Flamm RK, Mendes RE. Diagn Microbiol Infect Dis. 2022 Apr 22;103(3):115713. doi: 10.1016/j.diagmicrobio.2022.115713. Online ahead of print.

Plain language summary: Does a person's age affect how common fungal infections are and how well drugs can kill the infections? Pfaller MA, Carvalhaes CG, DeVries S, Huband MD, Castanheira M. Future Microbiol. 2022 May 20. doi: 10.2217/fmb-2022-0059. Online ahead of print.

Transcriptome and metabolome after porcine hemodynamic-directed CPR compared with standard CPR and sham controls. Senthil K, Hefti MM, Singh LN, Morgan RW, Mavroudis CD, Ko T, Gaudio H, Nadkarni VM, Ehinger J, Berg RA, Sutton RM, McGowan FX, Kilbaugh TJ. Resusc Plus. 2022 May 11;10:100243. doi: 10.1016/j.resplu.2022.100243. eCollection 2022 Jun.

IL-1R-IRAKM-Slc25a1 signaling axis reprograms lipogenesis in adipocytes to promote diet-induced obesity in mice. Liu W, Zhou H, Wang H, Zhang Q, Zhang R, Willard B, Liu C, Kang Z, Li X, Li X. Nat Commun. 2022 May 18;13(1):2748. doi: 10.1038/s41467-022-30470-w.

Reference Intervals for Clinical Chemistry Analytes for Transgender Men and Women on Stable Hormone Therapy. Humble RM, Greene DN, Schmidt RL, Winston McPherson G, Rongitsch J, Imborek KL, Nisly N, Dole NJ, Dane SK, Frerichs J, Krasowski MD. J Appl Lab Med. 2022 May 18:jfac025. doi: 10.1093/jalm/jfac025. Online ahead of print.

Machine learning approach informs biology of cancer drug response. Zhu EY, Dupuy AJ. BMC Bioinformatics. 2022 May 17;23(1):184. doi: 10.1186/s12859-022-04720-z.

Ultraviolet camera-aided sunscreen application in children: Demonstration of efficacy and receptivity. Thompson HJ, Frisbie R, Smith H, Craig E, Milhem M, Liu V. J Am Acad Dermatol. 2022 Jun;86(6):1390-1392. doi: 10.1016/j.jaad.2021.05.044. Epub 2021 May 29.


Week of May 17, 2022
Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Neurooncol Adv. 2022 Apr 9;4(1):vdac047. doi: 10.1093/noajnl/vdac047. eCollection 2022 Jan-Dec.

Neuropathology of COVID-19. Lin LC, Hollis B, Hefti MM. Indian J Pathol Microbiol. 2022 May;65(Supplement):S146-S152. doi: 10.4103/ijpm.ijpm_1103_21.

Transcriptional Profiling in a Novel Swine Model of Traumatic Brain Injury. Shin SS, Gottschalk AC, Mazandi VM, Kilbaugh TJ, Hefti MM. Neurotrauma Rep. 2022 Apr 19;3(1):178-184. doi: 10.1089/neur.2021.0051. eCollection 2022.

Limb-Girdle Muscular Dystrophy R9 due to a Novel Complex Insertion/Duplication Variant in FKRP Gene. Willis E, Moore SA, Cox MO, Stefans V, Aravindhan A, Gokden M, Veerapandiyan A. Child Neurol Open. 2022 Apr 28;9:2329048X221097518. doi: 10.1177/2329048X221097518. eCollection 2022 Jan-Dec.

MET exon 14 Skipping Mutations: Essential Considerations for Current Management of Non-Small-Cell Lung Cancer. Davies KD, Ritterhouse LL, Snow AN, Sidiropoulos N. J Mol Diagn. 2022 May 9:S1525-1578(22)00118-0. doi: 10.1016/j.jmoldx.2022.04.005. Online ahead of print.


Week of May 10, 2022
Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer. Furqan M, Abu-Hejleh T, Stephens LM, Hartwig SM, Mott SL, Pulliam CF, Petronek M, Henrich JB, Fath MA, Houtman JC, Varga SM, Bodeker KL, Bossler AD, Bellizzi AM, Zhang J, Monga V, Mani H, Ivanovic M, Smith BJ, Byrne MM, Zeitler W, Wagner BA, Buettner GR, Cullen JJ, Buatti JM, Spitz DR, Allen BG. Redox Biol. 2022 Apr 20;53:102318. doi: 10.1016/j.redox.2022.102318. Online ahead of print.

Lymphoplasma Exchange Improves Myasthenia Gravis Exacerbations: A Retrospective Study in a Chinese Center. Ouyang S, Yin W, Zeng Q, Li B, Zhang J, Duan W, Li Y, Liang Y, Wang J, Tan H, Yang H. Front Immunol. 2022 Apr 14;13:757841. doi: 10.3389/fimmu.2022.757841. eCollection 2022.

Impact of COVID-19 on the Antifungal Susceptibility Profiles of Isolates Collected in a Global Surveillance Program that Monitors Invasive Fungal Infections. Pfaller MA, Carvalhaes CG, DeVries S, Rhomberg PR, Castanheira M. Med Mycol. 2022 May 2;60(5):myac028. doi: 10.1093/mmy/myac028. Online ahead of print.

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis. Li Y, Talbot CL, Chandravanshi B, Ksiazek A, Sood A, Chowdhury KH, Maschek JA, Cox J, Babu AKS, Paz HA, Babu PVA, Meyerholz DK, Wankhade UD, Holland W, Shyong Tai E, Summers SA, Chaurasia B. Sci Rep. 2022 May 4;12(1):7273. doi: 10.1038/s41598-022-11219-3.

The frequency and significance of radiographic findings in the staging workup of patients with mycosis fungoides and Sezary syndrome. Eckburg A, Mott S, Dittmer M, Zafar F, Link B, Liu V. Int J Dermatol. 2022 May 4. doi: 10.1111/ijd.16178. Online ahead of print.

TH17 cells promote CNS inflammation by sensing danger signals via Mincle. Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, Zhang CJ, Zhao J, Zhang R, Liu C, Kang Z, Bermel RA, Dubyak G, Abbott DW, Xiao TS, Nagy LE, Li X. Nat Commun. 2022 May 3;13(1):2406. doi: 10.1038/s41467-022-30174-1.

Clinicopathologic Features of Facial Dermatofibromas, a Cohort Study, and a Systematic Review of Literature. Alsawas M, Dundar B, Prokop L, Murad MH, Swick B. Am J Dermatopathol. 2022 Apr 27. doi: 10.1097/DAD.0000000000002211. Online ahead of print.


Week of May 3, 2022
Dual diagnosis of histiocytoid Sweet syndrome and anti-neutrophil cytoplasmic antibody-associated vasculitis. Jónsdóttir H, Sanders ML, Goettsche L, Honkanen I, Schwartz A, Holanda D, Stone MS, Jabbari A. JAAD Case Rep. 2022 Apr 1;23:117-119. doi: 10.1016/j.jdcr.2022.03.007. eCollection 2022 May.

Staphylococcus aureus detection from CF respiratory samples is improved using alternative media. Zirbes CF, Pitcher NJ, Davis JC, Bartels AR, Krogh JD, Teresi M, Farber T, Milavetz F, Pamatmat AJ, Rozen AL, Reinhardt LD, Boyken L, Singh SB, Twait E, Reeb VC, Ford BA, Fischer AJ. J Cyst Fibros. 2022 Apr 28:S1569-1993(22)00105-9. doi: 10.1016/j.jcf.2022.04.017. Online ahead of print.

Duodenal adenocarcinoma presenting as duodenal cystic dystrophy. Durham K, Zheng X, Bosch DE, Ashat M. Gastrointest Endosc. 2022 Apr 26:S0016-5107(22)00334-0. doi: 10.1016/j.gie.2022.04.021. Online ahead of print.

Multiple sclerosis patients have an altered gut mycobiome and increased fungal to bacterial richness. Yadav M, Ali S, Shrode RL, Shahi SK, Jensen SN, Hoang J, Cassidy S, Olalde H, Guseva N, Paullus M, Cherwin C, Wang K, Cho T, Kamholz J, Mangalam AK. PLoS One. 2022 Apr 26;17(4):e0264556. doi: 10.1371/journal.pone.0264556. eCollection 2022.


Week of April 26, 2022
Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy. Tran CG, Borbon LC, Mudd JL, Abusada E, AghaAmiri S, Ghosh SC, Vargas SH, Li G, Beyer GV, McDonough M, Li R, Chan CHF, Walsh SA, Wadas TJ, O'Dorisio T, O'Dorisio MS, Govindan R, Cliften PF, Azhdarinia A, Bellizzi AM, Fields RC, Howe JR, Ear PH. Cancers (Basel). 2022 Apr 10;14(8):1910. doi: 10.3390/cancers14081910.

Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction. Lynch TJ, Ahlers BA, Swatek AM, Ievlev V, Pai AC, Brooks L, Tang Y, Evans IA, Meyerholz DK, Engelhardt JF, Parekh KR. Transplantation. 2022 Apr 15. doi: 10.1097/TP.0000000000004148. Online ahead of print.

Histologic Features of Dermal Regeneration Template Identified in Mohs Layer Frozen Sections. McGuinness AE, Richey PM, Stone MS, Ferguson NN. Dermatol Surg. 2022 Feb 1;48(2):253-255. doi: 10.1097/DSS.0000000000003322.

Week of April 19, 2022
Mitogen-Activated Protein Kinase Phosphatase-1 Controls PD-L1 Expression by Regulating Type I Interferon during Systemic Escherichia coli Infection. Barley TJ, Murphy PR, Wang X, Bowman BA, Mormol JM, Mager CE, Kirk SG, Cash CJ, Linn SC, Meng X, Nelin LD, Chen B, Hafner M, Zhang J, Liu Y. J Biol Chem. 2022 Apr 13:101938. doi: 10.1016/j.jbc.2022.101938. Online ahead of print.

Publisher Correction: Tcf1 preprograms the mobilization of glycolysis in central memory CD8+ T cells during recall responses. Shan Q, Hu SS, Zhu S, Chen X, Badovinac VP, Peng W, Zang C, Xue HH. Nat Immunol. 2022 Apr 12. doi: 10.1038/s41590-022-01202-5. Online ahead of print.


Week of April 12, 2022
Single-cell analysis of Sézary syndrome reveals novel markers and shifting gene profiles associated with treatment. Borcherding N, Severson KJ, Henderson NT, Dos Santos Ortolan L, Rosenthal AC, Bellizzi AM, Liu V, Link BK, Mangold AR, Jabbari A. Blood Adv. 2022 Apr 7:bloodadvances.2021005991. doi: 10.1182/bloodadvances.2021005991. Online ahead of print.

The evolution of microtubule associated proteins - a reference proteomic perspective. Gottschalk AC, Hefti MM. BMC Genomics. 2022 Apr 6;23(1):266. doi: 10.1186/s12864-022-08502-y.

Commentary on White blood cell transfusions for control of infections in neutropenic patients by Vallejos C. (Transfusion 1975; 15(1):28-33). Strauss RG. Transfusion. 2022 Apr;62(4):731-739. doi: 10.1111/trf.16859.

Antibodies against biotin-labeled red blood cells can shorten posttransfusion survival. Mock DM, Stowell SR, Franco RS, Kyosseva SV, Nalbant D, Schmidt RL, Cress GA, Strauss RG, Cancelas JA, von Goetz M, North AK, Widness JA. Transfusion. 2022 Apr;62(4):770-782. doi: 10.1111/trf.16849. Epub 2022 Mar 11.

Cross-sectional Neuromuscular Phenotyping Study of Patients With Arhinia With SMCHD1 Variants. Mohassel P, Chang N, Inoue K, Delaney A, Hu Y, Donkervoort S, Saade D, Billioux BJ, Meader B, Volochayev R, Konersman CG, Kaindl AM, Cho CH, Russell B, Rodriguez A, Foster KW, Foley AR, Moore SA, Jones PL, Bonnemann CG, Jones T, Shaw ND. Neurology. 2022 Mar 29;98(13):e1384-e1396. doi: 10.1212/WNL.0000000000200032. Epub 2022 Feb 4.

National Kidney Foundation Laboratory Engagement Working Group Recommendations for Implementing the CKD-EPI 2021 Race-Free Equations for Estimated Glomerular Filtration Rate: Practical Guidance for Clinical Laboratories. Miller WG, Kaufman HW, Levey AS, Straseski JA, Wilhelms KW, Yu HE, Klutts JS, Hilborne LH, Horowitz GL, Lieske J, Ennis JL, Bowling JL, Lewis MJ, Montgomery E, Vassalotti JA, Inker LA. Clin Chem. 2022 Mar 31;68(4):511-520. doi: 10.1093/clinchem/hvab278.

Renal Infarction in a Patient Found to Have a Dysproteinemia. Patel J, Holman CJ, Fraer M. Kidney360. 2020 Nov 25;1(11):1332-1333. doi: 10.34067/KID.0003082020. eCollection 2020 Nov 25.


Week of April 4, 2022
Comparison of Interleukin-1 Ligand Expression by Human Papilloma Virus Status in HNSCCs. Khan IN, Gibson-Corley KN, Coppock JD, Simons AL. Head Neck Pathol. 2022 Mar 25. doi: 10.1007/s12105-022-01440-x. Online ahead of print.

Plasma Neurofilament Light and Glial Fibrillary Acidic Protein Levels over 30 days in a Porcine Model of Traumatic Brain Injury. Shin S, Hefti MM, Mazandi VM, Issadore DA, Meaney D, Christman Schneider ALLC, Diaz-Arrastia R, Kilbaugh TJ. J Neurotrauma. 2022 Apr 4. doi: 10.1089/neu.2022.0070. Online ahead of print.

Centrizonal hepatocyte dropout in allograft liver biopsies: a clinicopathological study. Bosch DE, Swanson PE, Yeh MM. Histopathology. 2022 Mar;80(4):708-719. doi: 10.1111/his.14606. Epub 2022 Feb 7.


Week of March 29, 2022
Suspected Fanconi syndrome from cadmium toxicity exacerbated by heavy kratom use. A rare occurrence. Sekar A, Katzman S, O'Donnell M, Velani S, Conway KS. Clin Toxicol (Phila). 2022 Mar 24:1-2. doi: 10.1080/15563650.2022.2046774. Online ahead of print.

Eicosanoid signaling blockade protects middle-aged mice from severe COVID-19. Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Thurman A, Pezzulo AA, Szachowicz PJ, Li P, Pan R, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Zuniga S, Sola I, Enjuanes L, Meyerholz DK, Fortney K, McCray PB Jr, Perlman S. Nature. 2022 Mar 21. doi: 10.1038/s41586-022-04630-3. Online ahead of print.


Week of March 22, 2022
Case Report: Clinical and Pathological Findings of a Recurrent C3 Glomerulopathy With Superimposed Membranoproliferative Glomerulonephritis Pattern and Cryoglobulinemia Associated With COVID-19. Daneshgar N, Liang PI, Michels CJ, Nester CM, Harshman LA, Dai DF. Front Pediatr. 2022 Mar 4;10:827466. doi: 10.3389/fped.2022.827466. eCollection 2022.

Molecular Pathology Education: A Suggested Framework for Primary Care Resident Training in Genomic Medicine: A Report of the Association for Molecular Pathology Training and Education Committee. Arcila ME, Snow AN, Akkari YMN, Chabot-Richards D, Pancholi P, Tafe LJ. J Mol Diagn. 2022 Mar 15:S1525-1578(22)00064-2. doi: 10.1016/j.jmoldx.2021.12.013. Online ahead of print.

Oxidation of ferumoxytol by ionizing radiation releases iron. An electron paramagnetic resonance study. Petronek MS, Spitz DR, Buettner GR, Allen BG. J Radiat Res. 2022 Mar 17:rrac008. doi: 10.1093/jrr/rrac008. Online ahead of print.

Not All Küttner Tumors Are IgG4-Related Disease (IgG4-RD). Marcus KS, Hoffman HT, Rajan Kd A. Head Neck Pathol. 2021 Dec;15(4):1322-1327. doi: 10.1007/s12105-020-01268-3. Epub 2021 Jan 4.


Week of March 15, 2022
Tumor to Tumor Metastasis: A Case Report of Metastatic Angiosarcoma to an Ovarian Brenner Tumor and Review of the Literature. Dundar B, Alrwashdeh A, Dahmoush L. Int J Gynecol Pathol. 2022 Mar 11. doi: 10.1097/PGP.0000000000000854. Online ahead of print.

Clinical Images: Extranodal Natural Killer/T Cell Lymphoma As a Rare Mimicker of Granulomatosis With Polyangiitis. Strouse J, Rajan A, Chang HB, Dimachkie MD, Halbur C, Bettendorf B. Arthritis Rheumatol. 2022 Mar;74(3):474. doi: 10.1002/art.41956. Epub 2022 Jan 12.

Advancing Diagnostic Stewardship for Healthcare-Associated Infections, Antibiotic Resistance, and Sepsis. Curren EJ, Lutgring JD, Kabbani S, Diekema DJ, Gitterman S, Lautenbach E, Morgan DJ, Rock C, Salerno RM, McDonald LC. Clin Infect Dis. 2022 Mar 1;74(4):723-728. doi: 10.1093/cid/ciab672.


Week of March 8, 2022
Potential Role of MANF, an ER Stress Responsive Neurotrophic Factor, in Protecting Against Alcohol Neurotoxicity. Wen W, Li H, Luo J. Mol Neurobiol. 2022 Mar 7. doi: 10.1007/s12035-022-02786-7. Online ahead of print.

Evaluation of Rezafungin Provisional CLSI Clinical Breakpoints and Epidemiological Cutoff Values Tested against a Worldwide Collection of Contemporaneous Invasive Fungal Isolates (2019 to 2020). Carvalhaes CG, Klauer AL, Rhomberg PR, Pfaller MA, Castanheira M. J Clin Microbiol. 2022 Mar 7:e0244921. doi: 10.1128/jcm.02449-21. Online ahead of print.

Hemolytic disease of the fetus and newborn in the sensitizing pregnancy where anti-D was incorrectly identified as RhIG. Walhof ML, Leon J, Greiner AL, Scott JR, Knudson CM. J Clin Lab Anal. 2022 Mar 3:e24323. doi: 10.1002/jcla.24323. Online ahead of print.

Impact of Interfacing Near Point of Care Clinical Chemistry and Hematology Analyzers at Urgent Care Clinics at an Academic Health System. Fleishhacker ZJ, Rastogi P, Davis SR, Aman DR, Morris CS, Dyson RL, Krasowski MD. J Pathol Inform. 2022 Jan 20;13:100006. doi: 10.1016/j.jpi.2022.100006. eCollection 2022.

Extra-articular tophaceous gout of the Achilles tendon mimicking infection. Chen BC, Chen SJT, Duchman KR, Sekar P. BMJ Case Rep. 2022 Mar 2;15(3):e247647. doi: 10.1136/bcr-2021-247647.

A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. Am J Respir Cell Mol Biol. 2022 Mar 2. doi: 10.1165/rcmb.2021-0499OC. Online ahead of print.

Deficiency of mesencephalic astrocyte-derived neurotrophic factor affects neurogenesis in mouse brain. Wang Y, Wen W, Li H, Xu H, Xu M, Ma M, Luo J. Brain Res Bull. 2022 Feb 25;183:49-56. doi: 10.1016/j.brainresbull.2022.02.019. Online ahead of print.


Week of March 1, 2022
Genomic Profiling of Metastatic Uveal Melanoma Shows Frequent Coexisting BAP1 or SF3B1 and GNAQ/GNA11 Mutations and Correlation With Prognosis. Isaacson AL, Sompallae RR, Guseva NV, Bellizzi AM, Bossler AD, Ma D. Am J Clin Pathol. 2022 Feb 25:aqac019. doi: 10.1093/ajcp/aqac019. Online ahead of print.

Tcf1 preprograms the mobilization of glycolysis in central memory CD8+ T cells during recall responses. Shan Q, Hu SS, Zhu S, Chen X, Badovinac VP, Peng W, Zang C, Xue HH. Nat Immunol. 2022 Feb 21. doi: 10.1038/s41590-022-01131-3. Online ahead of print.

Coronavirus disease 2019 (COVID-19) research agenda for healthcare epidemiology. Mody L, Akinboyo IC, Babcock HM, Bischoff WE, Cheng VC, Chiotos K, Claeys KC, Coffey KC, Diekema DJ, Donskey CJ, Ellingson KD, Gilmartin HM, Gohil SK, Harris AD, Keller SC, Klein EY, Krein SL, Kwon JH, Lauring AS, Livorsi DJ, Lofgren ET, Merrill K, Milstone AM, Monsees EA, Morgan DJ, Perri LP, Pfeiffer CD, Rock C, Saint S, Sickbert-Bennett E, Skelton F, Suda KJ, Talbot TR, Vaughn VM, Weber DJ, Wiemken TL, Yassin MH, Ziegler MJ, Anderson DJ; SHEA Research Committee. Infect Control Hosp Epidemiol. 2022 Feb;43(2):156-166. doi: 10.1017/ice.2021.25. Epub 2021 Jan 25.

A Dramatic Presentation of Immune-Mediated Necrotizing Myopathy. Diel RJ, Hannah CE, Moore SA, Bettendorf B. J Clin Rheumatol. 2021 Dec 1;27(8S):S817-S818. doi: 10.1097/RHU.0000000000001443.


Week of February 22, 2022
Intron Mutations and Early Transcription Termination in Duchenne and Becker muscular dystrophy. Waldrop MA, Moore SA, Mathews KD, Darbro BW, Medne L, Finkel R, Connolly AM, Crawford TO, Drachman D, Wein N, Habib AA, Krzesniak-Swinarska MA, Zaidman CM, Collins JJ, Jokela M, Udd B, Day JW, Ortiz-Guerrero G, Statland J, Butterfield RJ, Dunn DM, Weiss RB, Flanigan KM. Hum Mutat. 2022 Feb 14. doi: 10.1002/humu.24343. Online ahead of print.

Association of ABO Blood Group, Age, Body Mass Index and Symptomatic COVID-19 Infection with Signal Levels of Antibodies to COVID-19. Maxwell T, Wendt L, Castaneda C, Marsden K, Merrill AE, Swartz SR, Steffen HA, Johnson A, Ten Eyck P, Kenne KA, Rysavy MB, Jackson JB. Gynecol Reprod Health. 2022; 6(1): 1-5.


Week of February 15, 2022
Use of a transnasal flexible laryngoscope tip for laryngeal culturing: A novel in-office technique. Michael A, Vesole AS, Diekema DJ, Stegall H, Hoffman HT. Laryngoscope Investig Otolaryngol. 2021 Dec 7;7(1):197-201. doi: 10.1002/lio2.712. eCollection 2022 Feb.

The inflammatory pathology of dysferlinopathy is distinct from calpainopathy, Becker muscular dystrophy, and inflammatory myopathies. Becker N, Moore SA, Jones KA. Acta Neuropathol Commun. 2022 Feb 8;10(1):17. doi: 10.1186/s40478-022-01320-z.

Posterior Embryotoxon Revisited: An Immunohistologic Study. Alwadani S, Alward WLM, Syed NA, Bouhenni RA, Brownstein S, Edward DP. Ophthalmol Glaucoma. 2022 Feb 4:S2589-4196(22)00018-7. doi: 10.1016/j.ogla.2022.01.003. Online ahead of print.

Perfusion with 10% neutral-buffered formalin is equivalent to 4% paraformaldehyde for histopathology and immunohistochemistry in a mouse model of experimental autoimmune encephalomyelitis. Snyder JM, Radaelli E, Goeken A, Businga T, Boyden AW, Karandikar NJ, Gibson-Corley KN. Vet Pathol. 2022 Feb 7:3009858221075588. doi: 10.1177/03009858221075588. Online ahead of print.

A Curriculum for Genomic Education of Molecular Genetic Pathology Fellows: A Report of the Association for Molecular Pathology Training and Education Committee. Rosenbaum JN, Berry AB, Church AJ, Crooks K, Gagan JR, López-Terrada D, Pfeifer JD, Rennert H, Schrijver I, Snow AN, Wu D, Ewalt MD. J Mol Diagn. 2021 Oct;23(10):1218-1240. doi: 10.1016/j.jmoldx.2021.07.001. Epub 2021 Jul 7.

Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria. Mishra A, Liu S, Promes J, Harata M, Sivitz W, Fink B, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens S, King T, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum J, Imai Y. JCI Insight. 2021 May 10;6(9):e144341. doi: 10.1172/jci.insight.144341.


Week of February 8, 2022
Cross-sectional, Neuromuscular Phenotyping Study of Arhinia Patients With SMCHD1 Variants. Mohassel P, Chang N, Inoue K, Delaney A, Hu Y, Donkervoort S, Saade D, Billioux BJ, Meader B, Volochayev R, Konersman CG, Kaindl AM, Cho CH, Russell B, Rodriguez A, Foster KW, Foley AR, Moore SA, Jones PL, Bonnemann CG, Jones T, Shaw ND. Neurology. 2022 Feb 4:10.1212/WNL.0000000000200032. doi: 10.1212/WNL.0000000000200032. Online ahead of print.

Attenuation of actinic prurigo eruptions with Polypodium leucotomos supplementation. Stump M, Dhinsa H, Powers J, Stone M. Pediatr Dermatol. 2022 Jan;39(1):145-146. doi: 10.1111/pde.14876. Epub 2021 Dec 9.

WDR26 and MTF2 are therapeutic targets in multiple myeloma. Sun F, Cheng Y, Riordan JD, Dupuy A, Dubois W, Pisano M, Dong J, Mock B, Zhan F, Hari P, Janz S. J Hematol Oncol. 2021 Dec 7;14(1):203. doi: 10.1186/s13045-021-01217-9.

Prevalence of Running as Aerobic Exercise among Students in a College of Medicine. Kallner K, Wendt L, Spring J, Jackson JB. J Medic Educ Training 2021; 5:069.


Week of February 1, 2022
Limited Variation between SARS-CoV-2-Infected Individuals in Domain Specificity and Relative Potency of the Antibody Response against the Spike Glycoprotein. Van Ert HA, Bohan DW, Rogers K, Fili M, Rojas Chávez RA, Qing E, Han C, Dempewolf S, Hu G, Schwery N, Sevcik K, Ruggio N, Boyt D, Pentella MA, Gallagher T, Jackson JB, Merrill AE, Knudson CM, Brown GD, Maury W, Haim H. Microbiol Spectr. 2022 Jan 26:e0267621. doi: 10.1128/spectrum.02676-21. Online ahead of print.

Quantum chemical insight into the effects of the local electron environment on T2*-based MRI. Petronek MS, St-Aubin JJ, Lee CY, Spitz DR, Gillan EG, Allen BG, Magnotta VA. Sci Rep. 2021 Oct 21;11(1):20817. doi: 10.1038/s41598-021-00305-7.

Ectopic Tcf1 expression instills a stem-like program in exhausted CD8+ T cells to enhance viral and tumor immunity. Shan Q, Hu S, Chen X, Danahy DB, Badovinac VP, Zang C, Xue HH. Cell Mol Immunol. 2021 May;18(5):1262-1277. doi: 10.1038/s41423-020-0436-5. Epub 2020 Apr 27


Week of January 25, 2022
Role of microbiome and metabolome in the pathobiology of MS. Mangalam AK, Giri S. Clin Immunol. 2022 Jan 20:108934. doi: 10.1016/j.clim.2022.108934. Online ahead of print.

Targeting Endoplasmic Reticulum Stress as an Effective Treatment for Alcoholic Pancreatitis. Li H, Wen W, Luo J. Biomedicines. 2022 Jan 5;10(1):108. doi: 10.3390/biomedicines10010108.

Elderly versus nonelderly patients with invasive fungal infections: species distribution and antifungal resistance, SENTRY antifungal surveillance program 2017-2019. Pfaller MA, Carvalhaes CG, DeVries S, Huband MD, Castanheira M. Diagn Microbiol Infect Dis. 2021 Dec 24;102(4):115627. doi: 10.1016/j.diagmicrobio.2021.115627. Online ahead of print.

Implementation and assessment of an effective, novel, student-centered, remotely accessible, dermatology education program: A prospective cohort study. Poggemiller AM, Kreiter C, Naridze R, Melrose E, Fenton P, Wanat KA, Liu V. J Am Acad Dermatol. 2021 Dec;85(6):1645-1647. doi: 10.1016/j.jaad.2021.01.011. Epub 2021 Jan 8.

Induction and maintenance of remission with mycophenolate mofetil in ANCA-associated vasculitis: A systematic review and meta-analysis. Berti A, Alsawas M, Jawaid T, Prokop LJ, Lee JM, Jeong GH, Quintana LF, Moiseev S, Vaglio A, Tesar V, Geetha D, Shin JI, Kronbichler A. Nephrol Dial Transplant. 2021 Dec 15:gfab357. doi: 10.1093/ndt/gfab357. Epub ahead of print. 


Week of January 18, 2022
Data on the frequency and causes of icteric interference in clinical chemistry laboratory tests. Merrill AE, Mainali S, Krasowski MD. Data Brief. 2021 Dec 30;40:107771. doi: 10.1016/j.dib.2021.107771. eCollection 2022 Feb.

Novel Mouse Model of Murine Cytomegalovirus-Induced Adaptive NK Cells. Jensen IJ, Martin MD, Tripathy SK, Badovinac VP. Immunohorizons. 2022 Jan 14;6(1):8-15. doi: 10.4049/immunohorizons.2100113.

Respiratory Syncytial Virus Provides Protection against a Subsequent Influenza A Virus Infection. Hartwig SM, Miller AM, Varga SM. J Immunol. 2022 Jan 12:ji2000751. doi: 10.4049/jimmunol.2000751. Online ahead of print.

Oral estrogen leads to falsely low concentrations of estradiol in a common immunoassay. Cirrincione LR, Crews BO, Dickerson JA, Krasowski MD, Rongitsch J, Imborek KL, Goldstein Z, Greene DN. Endocr Connect. 2022 Jan 1:EC-21-0550.R1. doi: 10.1530/EC-21-0550. Online ahead of print.

Skeletal Muscle Regeneration: A Potential Histologic Pitfall for the Mohs Surgeon. Richey PM, Patrick AP, Swick BL, Van Beek MJ. Dermatol Surg. 2022 Jan 5. doi: 10.1097/DSS.0000000000003372. Online ahead of print.


Week of January 11, 2022
Implementation of large-scale laboratory-based detection of COVID-19 in the Veterans Health Administration, March 2020 - February 2021. Sharma A, Oda G, Icardi M, Mole L, Holodniy M. Diagn Microbiol Infect Dis. 2021 Dec 11;102(3):115617. doi: 10.1016/j.diagmicrobio.2021.115617. Online ahead of print.

Impact of COVID-19 on an infection prevention and control program, Iowa 2020-2021. Alsuhaibani M, Kobayashi T, McPherson C, Holley S, Marra AR, Trannel A, Dains A, Abosi OJ, Jenn KE, Meacham H, Sheeler L, Etienne W, Kukla ME, Wellington M, Edmond MB, Diekema DJ, Salinas JL. Am J Infect Control. 2021 Dec 23:S0196-6553(21)00763-X. doi: 10.1016/j.ajic.2021.11.015. Online ahead of print.

Medullary Serotonergic Binding Deficits and Hippocampal Abnormalities in Sudden Infant Death Syndrome: One or Two Entities? Haynes RL, Kinney HC, Haas EA, Duncan JR, Riehs M, Trachtenberg F, Armstrong DD, Alexandrescu S, Cryan JB, Hefti MM, Krous HF, Goldstein RD, Sleeper LA. Front Pediatr. 2021 Dec 21;9:762017. doi: 10.3389/fped.2021.762017. eCollection 2021.

Administration of Human Derived Upper gut Commensal Prevotella histicola delays the onset of type 1 diabetes in NOD mice. Marietta E, Horwath I, Meyer S, Khaleghi-Rostamkolaei S, Norman E, Luckey D, Balakrishnan B, Mangalam A, Choung RS, Taneja V, Murray JA. BMC Microbiol. 2022 Jan 4;22(1):8. doi: 10.1186/s12866-021-02406-9.

Antifungal drugs work together to treat germs causing fungal infections. Pfaller MA, Messer SA, Deshpande LM, Rhomberg PR, Utt EA, Castanheira M. Future Microbiol. 2021 Jul;16:765-768. doi: 10.2217/fmb-2021-0086. Epub 2021 Jun 29.


Week of January 4, 2022
Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits. Cooper TK, Meyerholz DK, Beck AP, Delaney MA, Piersigilli A, Southard TL, Brayton CF. ILAR J. 2022 Jan 4:ilab022. doi: 10.1093/ilar/ilab022. Online ahead of print.

COVID-19-associated necrotizing encephalopathy presenting without active respiratory symptoms: a case report with histopathology. Rettenmaier LA, Abdel-Wahed L, Abdelmotilib H, Conway KS, Narayanan N, Groth CL. J Neurovirol. 2021 Dec 30:1-5. doi: 10.1007/s13365-021-01042-3. Online ahead of print.

Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease. Aggarwal N, Deerhake ME, DiPalma D, Shahi SK, Gaggioli MR, Mangalam AK, Shinohara ML. Cell Rep. 2021 Dec 28;37(13):110170. doi: 10.1016/j.celrep.2021.110170.

Identification of HnRNPC as a novel Tau exon 10 splicing factor using RNA antisense purification mass spectrometry. Xing S, Wang J, Wu R, Hefti MM, Crary JF, Lu Y. RNA Biol. 2021 Dec 29:1-13. doi: 10.1080/15476286.2021.2015175. Online ahead of print.

The Neuropathology of 1p36 Deletion Syndrome: An Autopsy Case Series. Conway KS, Ghafoor F, Gottschalk AC, Laakman J, Eigsti RL, Nashelsky M, Blau J, Hefti MM. J Neuropathol Exp Neurol. 2021 Sep 27;80(9):856-860. doi: 10.1093/jnen/nlab072.

Genomic Analysis of Vascular Invasion in HCC Reveals Molecular Drivers and Predictive Biomarkers. Krishnan MS, Rajan Kd A, Park J, Arjunan V, Garcia Marques FJ, Bermudez A, Girvan OA, Hoang NS, Yin J, Nguyen MH, Kothary N, Pitteri S, Felsher DW, Dhanasekaran R. Hepatology. 2021 Jun;73(6):2342-2360. doi: 10.1002/hep.31614. Epub 2021 May 8.


Week of December 28, 2021
Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations. Daneshgar N, Liang PI, Lan RS, Horstmann M, Pack L, Bhardwaj G, Penniman CM, O'Neill BT, Dai DF. Kidney Int. 2021 Dec 22:S0085-2538(21)01164-9. doi: 10.1016/j.kint.2021.12.006. Online ahead of print.

Catalase Overexpression Drives an Aggressive Phenotype in Glioblastoma. Flor S, Oliva CR, Ali MY, Coleman KL, Greenlee JD, Jones KA, Monga V, Griguer CE. Antioxidants (Basel). 2021 Dec 14;10(12):1988. doi: 10.3390/antiox10121988.

A Recursive Partitioning Analysis Demonstrating Risk Subsets for 8-Year Biochemical Relapse After Margin-Positive Radical Prostatectomy Without Adjuvant Hormone or Radiation Therapy. Seyedin SN, Watkins JM, Mayo Z, Snow AN, Laszewski M, Russo JK, Mott SL, Tracy CR, Smith MC, Buatti JM, Caster JM. Adv Radiat Oncol. 2021 Aug 14;6(6):100778. doi: 10.1016/j.adro.2021.100778. eCollection 2021 Nov-Dec.

Metallothionein immunohistochemistry has high sensitivity and specificity for detection of Wilson disease. Rowan DJ, Mangalaparthi KK, Singh S, Moreira RK, Mounajjed T, Lamps L, Westerhoff M, Cheng J, Bellizzi AM, Allende DS, Pandey A, Graham RP. Mod Pathol. 2021 Dec 21. doi: 10.1038/s41379-021-01001-7. Online ahead of print.


Week of December 21, 2021
In vitro activity of a novel aminomethylcycline antibacterial (KBP-7072), a third-generation tetracycline, against clinical isolates with molecularly characterized tetracycline resistance mechanisms. Pfaller MA, Li L, Liu Q, Zhang J, Huband MD, Lindley JM, Mendes RE. JAC Antimicrob Resist. 2021 Dec 14;3(4):dlab177. doi: 10.1093/jacamr/dlab177. eCollection 2021 Dec.

Days of Antibiotic Spectrum Coverage (DASC): A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2021 Dec 15:ciab1034. doi: 10.1093/cid/ciab1034. Online ahead of print.

Ceftolozane-tazobactam activity against clinical isolates of Pseudomonas aeruginosa from ICU patients with pneumonia: United States, 2015-2018. Pfaller MA, Shortridge D, Harris KA, Garrison MW, DeRyke CA, DePestel DD, Moise PA, Sader HS. Int J Infect Dis. 2021 Nov;112:321-326. doi: 10.1016/j.ijid.2021.09.064. Epub 2021 Sep 29.


Week of December 14, 2021
Analysis of entire hepatitis B virus genomes reveals reversion of mutations to wild type in natural infection, a 15 year follow-up study. Chen QY, Jia HH, Wang XY, Shi YL, Zhang LJ, Hu LP, Wang C, He X, Harrison TJ, Jackson JB, Wu L, Fang ZL.Infect Genet Evol. 2021 Dec 10:105184. doi: 10.1016/j.meegid.2021.105184. Online ahead of print.

Paraneoplastic erythema annulare centrifugum associated with mycosis fungoides. Thompson HJ, King BJ, Link B, Liu V. JAAD Case Rep. 2021 Oct 5;17:65-68. doi: 10.1016/j.jdcr.2021.09.027. eCollection 2021 Nov.

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium. Yamanashi T, Nagao T, Wahba NE, Marra PS, Crutchley KJ, Meyer AA, Andreasen AJ, Hellman MM, Jellison SS, Hughes CG, Pandharipande PP, Howard Iii MA, Kawasaki H, Iwata M, Hefti MM, Shinozaki G.Transl Psychiatry. 2021 Dec 9;11(1):627. doi: 10.1038/s41398-021-01752-6.

Data on the utilization of paraneoplastic syndrome autoantibody testing at an academic medical center. Krasowski MD, Dolezal A, Steussy BW, Gailey MP, Darbro BW.Data Brief. 2021 Nov 18;39:107578. doi: 10.1016/j.dib.2021.107578. eCollection 2021 Dec.


Week of December 7, 2021
Using nasal povidone-iodine to prevent bloodstream infections and transmission of Staphylococcus aureus among haemodialysis patients: a stepped-wedge cluster randomised control trial protocol. Racila AM, O'Shea AMJ, Nair R, Dukes K, Herwaldt LA, Boyken L, Diekema D, Ward MA, Cobb J, Jacob J, Pegues D, Bleasdale S, Vijayan A, Mutneja A, Fraer M, O'Connell-Moore D, Tolomeo P, Mendez M, Jaworski E, Schweizer ML. BMJ Open. 2021 Dec 3;11(12):e048830. doi: 10.1136/bmjopen-2021-048830.

SARS-CoV-2 antibody changes in patients receiving COVID-19 convalescent plasma from normal and vaccinated donors. Leon J, Merrill AE, Rogers K, Kurt J, Dempewolf S, Ehlers A, Jackson JB, Knudson CM. Transfus Apher Sci. 2021 Nov 23:103326. doi: 10.1016/j.transci.2021.103326. Online ahead of print.

The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice. Simonsen D, Cady N, Zhang C, Shrode RL, McCormick ML, Spitz DR, Chimenti MS, Wang K, Mangalam A, Lehmler HJ. Toxicol Sci. 2021 Nov 29:kfab142. doi: 10.1093/toxsci/kfab142. Online ahead of print.

Optimal Urine Culture Diagnostic Stewardship Practice- Results from an Expert Modified-Delphi Procedure. Claeys KC, Trautner BW, Leekha S, Coffey KC, Crnich CJ, Diekema D, Fakih MG, Goetz MB, Gupta K, Jones MM, Leykum L, Liang SY, Pineles L, Pleiss A, Spivak ES, Suda KJ, Taylor J, Rhee C, Morgan DJ. Clin Infect Dis. 2021 Nov 29:ciab987. doi: 10.1093/cid/ciab987. Online ahead of print.


Week of November 30, 2021
Centrizonal hepatocyte dropout in allograft liver biopsies: A clinicopathologic study. Bosch DE, Swanson PE, Yeh MM. Histopathology. 2021 Nov 29. doi: 10.1111/his.14606. Online ahead of print.

Molecular Pathology Education: An AMP Webinar Series on Emerging and Evolving Biomarkers Structured for Specific Audiences. Barker LP, Ritterhouse LL, Snow AN, Davies KD. J Mol Diagn. 2021 Nov 24:S1525-1578(21)00389-5. doi: 10.1016/j.jmoldx.2021.11.003. Online ahead of print.

Meningitis Caused by the Live Varicella Vaccine Virus: Metagenomic Next Generation Sequencing, Immunology Exome Sequencing and Cytokine Multiplex Profiling. Ramachandran PS, Wilson MR, Catho G, Blanchard-Rohner G, Schiess N, Cohrs RJ, Boutolleau D, Burrel S, Yoshikawa T, Wapniarski A, Heusel EH, Carpenter JE, Jackson W, Ford BA, Grose C. Viruses. 2021 Nov 16;13(11):2286. doi: 10.3390/v13112286.

Data on the relationship between lamotrigine and levetiracetam serum/plasma levels and toxicity: Experience at an academic medical center. Wood KE, Palmer KL, Krasowski MD. Data Brief. 2021 Nov 8;39:107555. doi: 10.1016/j.dib.2021.107555. eCollection 2021 Dec.

Data on the Relationships of Signal-To-Cutoff Ratios of Elecsys HIV Antigen/Antibody and Elecsys Syphilis Assays to Subsequent Confirmatory Testing at an Academic Medical Center. Chopra S, Krasowski MD. Data Brief. 2021 Nov 6;39:107549. doi: 10.1016/j.dib.2021.107549. eCollection 2021 Dec.


Week of November 23, 2021
Influence of SARS-CoV-2 on airway mucus production: A review and proposed model. Meyerholz DK, Reznikov LR. Vet Pathol. 2021 Nov 18:3009858211058837. doi: 10.1177/03009858211058837. Online ahead of print.

An elderly man with bilateral cavitary lesions in the globus pallidus. Halvorson TS, Stauffer SL, Jones KA. Brain Pathol. 2021 Nov 16:e13025. doi: 10.1111/bpa.13025. Online ahead of print.