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Recent Publications

Week of July 20, 2021
Deep Neural Network Analysis of Pathology Images With Integrated Molecular Data for Enhanced Glioma Classification and Grading. Pei L, Jones KA, Shboul ZA, Chen JY, Iftekharuddin KM. Front Oncol. 2021 Jul 1;11:668694. doi: 10.3389/fonc.2021.668694. eCollection 2021.

Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma. Mondello P, Fama A, Larson MC, Feldman AL, Villasboas JC, Yang ZZ, Galkin I, Svelolkin V, Postovalova E, Bagaev A, Ovcharov P, Varlamova A, Huet S, Tesson B, McGrath KR, Slager S, Link BK, Syrbu S, Novak AJ, Habermann TM, Witzig TE, Nowakowski GS, Salles G, Cerhan JR, Ansell SM. Blood Cancer J. 2021 Jul 15;11(7):130. doi: 10.1038/s41408-021-00521-4.

Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer. Chau J, Yadav M, Liu B, Furqan M, Dai Q, Shahi S, Gupta A, Mercer KN, Eastman E, Hejleh TA, Chan C, Weiner GJ, Cherwin C, Lee STM, Zhong C, Mangalam A, Zhang J. BMC Cancer. 2021 Jul 13;21(1):808. doi: 10.1186/s12885-021-08530-z.

Side-Effects of COVID-19 on Patient Care: An INR Story. Pearson LN, Johnson SA, Greene DN, Chambliss AB, Farnsworth CW, French D, Herman DS, Kavsak PA, Merrill AE, Lo SM, Lyon ME, SoRelle JA, Schmidt RL. J Appl Lab Med. 2021 Jul 7;6(4):953-961. doi: 10.1093/jalm/jfab025.


 Week of July 13, 2021

Evaluation of the In vivo Antitumor Activity of Polyanhydride IL-1α Nanoparticles. Hasibuzzaman MM, Ross KA, Salem AK, Narasimhan B, Simons AL. J Vis Exp. 2021 Jun 28;(172). doi: 10.3791/62683.

COVID-19 Incidence After Exposures in Shared Patient Rooms, Tertiary Care Center, Iowa, July 2020-May 2021. Trannel A, Kobayashi T, Dains A, Abosi OJ, Jenn KE, Meacham H, Sheeler LL, Etienne W, Kukla ME, Alsuhaibani M, Holley S, Strandberg K, Marra AR, Kritzman J, Ford B, Wellington M, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2021 Jul 12:1-13. doi: 10.1017/ice.2021.313. Online ahead of print.

A Curriculum for Genomic Education of Molecular Genetic Pathology Fellows:A Report of the Association for Molecular Pathology Training and Education Committee. Rosenbaum JN, Berry AB, Church AJ, Crooks K, Gagan JR, López-Terrada D, Pfeifer JD, Rennert H, Schrijver I, Snow AN, Wu D, Ewalt MD. J Mol Diagn. 2021 Jul 7:S1525-1578(21)00201-4. doi: 10.1016/j.jmoldx.2021.07.001. Online ahead of print.

Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis. Jensen SN, Cady NM, Shahi SK, Peterson SR, Gupta A, Gibson-Corley KN, Mangalam AK. Sci Adv. 2021 Jul 9;7(28):eabd4595. doi: 10.1126/sciadv.abd4595. Print 2021 Jul.

Molecular epidemiology of large coronavirus disease 2019 (COVID-19) clusters before and after the implementation of routine serial testing at an academic medical center in Iowa, 2020. Ortiz ME, Kobayashi T, Imborek K, Alsuhaibani M, Holley S, Trannel A, Marra AR, Etienne W, Jenn KE, Abosi OJ, Meacham H, Sheeler L, Dains A, Kukla ME, McCray PB, Perlman S, Ford B, Diekema DJ, Wellington M, Pezzulo AA, Salinas JL. Infect Control Hosp Epidemiol. 2021 Jun 24:1-3. doi: 10.1017/ice.2021.301. Online ahead of print.

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Dampalla CS, Zheng J, Perera KD, Wong LR, Meyerholz DK, Nguyen HN, Kashipathy MM, Battaile KP, Lovell S, Kim Y, Perlman S, Groutas WC, Chang KO. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2101555118. doi: 10.1073/pnas.2101555118.

Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma. Oishi N, Hundal T, Phillips JL, Dasari S, Hu G, Viswanatha DS, He R, Mai M, Jacobs HK, Ahmed NH, Syrbu SI, Salama Y, Chapman JR, Vega F, Sidhu J, Bennani NN, Epstein AL, Medeiros JL, Clemens MW, Miranda RN, Feldman AL. Haematologica. 2021 Jun 1;106(6):1714-1724. doi: 10.3324/haematol.2019.245860.


Week of July 6, 2021
Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model. Senthil K, Morgan RW, Hefti MM, Karlsson M, Lautz AJ, Mavroudis CD, Ko T, Nadkarni VM, Ehinger J, Berg RA, Sutton RM, McGowan FX, Kilbaugh TJ. Resusc Plus. 2021 Apr 29;6:100124. doi: 10.1016/j.resplu.2021.100124. eCollection 2021 Jun.

Use of Middleware Data to Dissect and Optimize Hematology Autoverification. Starks RD, Merrill AE, Davis SR, Voss DR, Goldsmith PJ, Brown BS, Kulhavy J, Krasowski MD. J Pathol Inform. 2021 Apr 7;12:19. doi: 10.4103/jpi.jpi_89_20. eCollection 2021.

MRSA Strains with Distinct Accessory Genes Predominate at Different Ages in Cystic Fibrosis. Porterfield HS, Maakestad LJ, LaMarche MM, Thurman AL, Kienenberger ZE, Pitcher NJ, Hansen AR, Zirbes CF, Boyken L, Muyskens BL, Pezzulo AA, Singh SB, Twait E, Ford B, Diekema DJ, Reeb V, Fischer AJ. Pediatr Pulmonol. 2021 Jul 5. doi: 10.1002/ppul.25559. Online ahead of print.

Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5-based COVID-19 vaccine. An D, Li K, Rowe DK, Diaz MCH, Griffin EF, Beavis AC, Johnson SK, Padykula I, Jones CA, Briggs K, Li G, Lin Y, Huang J, Mousa J, Brindley M, Sakamoto K, Meyerholz DK, McCray PB Jr, Tompkins SM, He B. Sci Adv. 2021 Jul 2;7(27):eabi5246. doi: 10.1126/sciadv.abi5246. Print 2021 Jul.

Iron-Refractory Iron Deficiency Anemia in an 11-year-old Girl. Swaminathan N, Lieberman SM, Bhagavathi S, Sharathkumar A. Pediatr Rev. 2021 Jul;42(7):393-398. doi: 10.1542/pir.2020-0081.

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Dampalla CS, Zheng J, Perera KD, Wong LR, Meyerholz DK, Nguyen HN, Kashipathy MM, Battaile KP, Lovell S, Kim Y, Perlman S, Groutas WC, Chang KO. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2101555118. doi: 10.1073/pnas.2101555118.

Considerations for a Respiratory Syncytial Virus Vaccine Targeting an Elderly Population. Stephens LM, Varga SM. Vaccines (Basel). 2021 Jun 9;9(6):624. doi: 10.3390/vaccines9060624.

Successful Patient-Derived Organoid Culture of Gynecologic Cancers for Disease Modeling and Drug Sensitivity Testing. Bi J, Newtson AM, Zhang Y, Devor EJ, Samuelson MI, Thiel KW, Leslie KK. Cancers (Basel). 2021 Jun 10;13(12):2901. doi: 10.3390/cancers13122901.

RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo. Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. Biomedicines. 2021 Jun 2;9(6):633. doi: 10.3390/biomedicines9060633.

A plain language summary of the EXPLORER-HCM study: mavacamten for obstructive hypertrophic cardiomyopathy. Pfaller MA, Messer SA, Deshpande LM, Rhomberg PR, Utt EA, Castanheira M. Future Microbiol. 2021 Jun 29. doi: 10.2217/fmb-2021-0086.

Sepsis, Cytokine Storms, and Immunopathology: The Divide between Neonates and Adults. Greenfield KG, Badovinac VP, Griffith TS, Knoop KA. Immunohorizons. 2021 Jun 28;5(6):512-522. doi: 10.4049/immunohorizons.2000104.


Week of June 29, 2021
Early Lung Disease Exhibits Bacterial-Dependent and -Independent Abnormalities in Cystic Fibrosis Pigs. Bouzek DC, Abou Alaiwa MH, Adam RJ, Pezzulo AA, Reznikov LR, Cook DP, Aguilar Pescozo MI, Ten Eyck P, Wu C, Gross TJ, Hornick DB, Hoffman EA, Meyerholz DK, Stoltz DA. Am J Respir Crit Care Med. 2021 Jun 25. doi: 10.1164/rccm.202102-0451OC. Online ahead of print.

COVID-19 Admission Screening, and Assessment of Infectiousness at an Academic Medical Center, Iowa 2020. Alsuhaibani M, Kobayashi T, Trannel A, Holley S, Abosi OJ, Jenn KE, Meacham H, Sheeler L, Etienne W, Dains A, Kukla ME, Ward E, Ford B, Edmond MB, Wellington M, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2021 Jun 24:1-19. doi: 10.1017/ice.2021.294. Online ahead of print.

Umbilical Cord Drug Screening in Multiple Births: Experience from a Reference Laboratory and Academic Medical Center. Nelson HA, Wood KE, McMillin GA, Krasowski MD. J Anal Toxicol. 2021 Jun 24:bkab077. doi: 10.1093/jat/bkab077. Online ahead of print.

Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle. Moose DL, Williams-Perez S, Cafun R, Krog BL, Henry MD. J Vis Exp. 2021 Apr 27;(170). doi: 10.3791/62478.

Aberrant redox biology and epigenetic reprogramming: Co-conspirators across multiple human diseases. Domann FE, Hitchler MJ. Free Radic Biol Med. 2021 Jul;170:2-5. doi: 10.1016/j.freeradbiomed.2021.04.020. Epub 2021 Apr 29.

Introduction to the special issue on 'epigenetics and redox signaling'. Domann FE, Hitchler MJ. Free Radic Biol Med. 2021 Jul;170:1. doi: 10.1016/j.freeradbiomed.2021.04.015. Epub 2021 Apr 13.

The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development. Hitchler MJ, Domann FE. Free Radic Biol Med. 2021 Jul;170:70-84. doi: 10.1016/j.freeradbiomed.2021.01.008. Epub 2021 Jan 12.

Political party preference of freshmen university students and its association with student lifestyle characteristics and the influence of 1 year public university. Pohl D, Choi A, Marcus K, Ten Eyck P, Jackson JB. J Child and Adolescent Health 2021:5-1-12.


Week of June 22, 2021
Prolonged Reactive Oxygen Species Production following Septic Insult. Jensen IJ, McGonagill PW, Berton RR, Wagner BA, Silva EE, Buettner GR, Griffith TS, Badovinac VP. Immunohorizons. 2021 Jun 18;5(6):477-488. doi: 10.4049/immunohorizons.2100027.

Protective function and durability of mouse lymph node-resident memory CD8+ T cells. Anthony SM, Van Braeckel-Budimir N, Moioffer SJ, van de Wall S, Shan Q, Vijay R, Sompallae R, Hartwig SM, Jensen IJ, Varga SM, Butler NS, Xue HH, Badovinac VP, Harty JT.Elife. 2021 Jun 18;10:e68662. doi: 10.7554/eLife.68662.


Week of June 8, 2021
SETDB1 in cancer: overexpression and its therapeutic implications. Lazaro-Camp VJ, Salari K, Meng X, Yang S. Am J Cancer Res. 2021 May 15;11(5):1803-1827. eCollection 2021.

Successful autologous peripheral blood stem cell collection using large volume leukapheresis in patients with very low or undetectable peripheral blood CD34+ progenitor cells. Destrampe E, Schlueter AJ. Transfus Apher Sci. 2021 May 21:103170. doi: 10.1016/j.transci.2021.103170. Online ahead of print.

Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results. Ma DC, Anderson CM, Rodman SN, Buranasudja V, McCormick ML, Davis A, Loth E, Bodeker KL, Ahmann L, Parkhurst JR, Sun W, Follmer KR, Simons AL, Buatt JM, Spitz DR, Fath MA, Allen BG. Radiat Res. 2021 Jun 4. doi: 10.1667/RADE-20-00150.1. Online ahead of print.

Skeletal Muscle Regeneration in Post-Myofascial Flap Reconstruction Specimens Mimicking Sarcoma: A Potential Diagnostic Pitfall. Patrick AP, Swick BL. J Cutan Pathol. 2021 Jun 4. doi: 10.1111/cup.14074. Online ahead of print.

ANCA GLOMERULONEPHRITIS POST MODERNA COVID-19 VACCINATION. Sekar A, Campbell R, Tabbara J, Rastogi P. Kidney Int. 2021 May 31:S0085-2538(21)00555-X. doi: 10.1016/j.kint.2021.05.017. Online ahead of print.

Diagnostic Challenges of Focal Nodular Hyperplasia: Interobserver Variability, Accuracy, and the Utility of Glutamine Synthetase Immunohistochemistry. Rowan DJ, Allende DS, Bellizzi AM, Gill RM, Liu X, McKenzie CA, Moreira RK, Mounajjed T, Said S, Westerhoff M, Jenkins SM, Batts KP, Burgart LJ, Lamps LW, Graham RP. Histopathology. 2021 Jun 3. doi: 10.1111/his.14424. Online ahead of print.

Mitochondria in epithelial ovarian carcinoma exhibit abnormal phenotypes and blunted associations with biobehavioral factors. Bindra S, McGill MA, Triplett MK, Tyagi A, Thaker PH, Dahmoush L, Goodheart MJ, Ogden RT, Owusu-Ansah E, R Karan K, Cole S, Sood AK, Lutgendorf SK, Picard M. Sci Rep. 2021 Jun 2;11(1):11595. doi: 10.1038/s41598-021-89934-6.

RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner. Kohlmeyer JL, Kaemmer CA, Umesalma S, Gourronc FA, Klingelhutz AJ, Quelle DE. Int J Mol Sci. 2021 May 20;22(10):5367. doi: 10.3390/ijms22105367.

Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. Zheng J, Meyerholz D, Wong LR, Gelb M, Murakami M, Perlman S. J Clin Invest. 2021 Jun 1;131(11):147201. doi: 10.1172/JCI147201.

A Hot Flash about Menopause Hormone Therapy. Johnson A, Graf E, Jackson JB. Clin Rev Cases. 2021; 3(1):1-4.

COVID-19 Infection and Disease Severity not associated with Increased Parity among Pregnant Women. Marsden KA, Ten Eyck PP, Maxwell TN, Castaneda CN, Kenne KA, Swartz SR, Steffen HA, Jackson JB, Rysavy MB. J Med - Clin Res & Rev. 2021; 5(6): 1-4.

Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence. Wong LR, Zheng J, Sariol A, Lowery S, Meyerholz DK, Gallagher T, Perlman S. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2102983118. doi: 10.1073/pnas.2102983118.


Week of June 1, 2021
Antimicrobial Activity of First-in-Class Antifungal, Manogepix, and Comparator Agents Testing against Contemporary Invasive Fungal Isolates from an International Surveillance Program (2018-2019): In Vitro Activity of Manogepix against Fungal Isolates. Pfaller MA, Huband MD, Flamm RK, Bien PA, Castanheira M. J Glob Antimicrob Resist. 2021 May 26:S2213-7165(21)00111-9. doi: 10.1016/j.jgar.2021.04.012. Online ahead of print.

Teaching Pathology in an Integrated Preclinical Medical School Curriculum and Adaptations to COVID-19 Restrictions. Krasowski MD, Blau JL, Chen SJ, Jones KA, Schmidt TJ, Bruch LA. Acad Pathol. 2021 May 19;8:23742895211015337. doi: 10.1177/23742895211015337. eCollection 2021 Jan-Dec.

Knockout of MAPK Phosphatase-1 Exaggerates Type I IFN Response during Systemic Escherichia coli Infection. Kirk SG, Murphy PR, Wang X, Cash CJ, Barley TJ, Bowman BA, Batty AJ, Ackerman WE 4th, Zhang J, Nelin LD, Hafner M, Liu Y. J Immunol. 2021 May 26:ji2001468. doi: 10.4049/jimmunol.2001468. Online ahead of print.


Week of May 25, 2021
Chronic alcohol exposure promotes HCC stemness and metastasis through β-catenin/miR-22-3p/TET2 axis. Chen D, Yan Y, Wang X, Li S, Liu Y, Yu D, He Y, Deng R, Liu Y, Xu M, Luo J, Gao H, Wang S. Aging (Albany NY). 2021 May 21;13. doi: 10.18632/aging.203059. Online ahead of print.

A Review of Clinical and Imaging Findings in Tumefactive Demyelination. Nakayama M, Naganawa S, Ouyang M, Jones KA, Kim J, Capizzano AA, Moritani T. AJR Am J Roentgenol. 2021 May 19:1-12. doi: 10.2214/AJR.20.23226. Online ahead of print.

Patient Portal Activation and Use in Hospitalized Children at an Academic Medical Center. Wood KE, Greene HR, Krasowski MD. Hosp Pediatr. 2021 May 18:hpeds.2020-003707. doi: 10.1542/hpeds.2020-003707. Online ahead of print.

Palliative care consultation in patients with Staphylococcus aureus bacteremia. Kobayashi T, Salinas JL, Ten Eyck P, Chen B, Ando T, Inagaki K, Alsuhaibani M, Auwaerter PG, Molano I, Diekema DJ. Palliat Med. 2021 Apr;35(4):785-792. doi: 10.1177/0269216321999574. Epub 2021 Mar 24.

Up-front Treatment With Romiplostim in Children With Acquired Bone Marrow Failure: A Single Institutional Pediatric Case Series. Al-Huniti A, Rathi N, Modi A, Bhagavathi S, Mitten R, Sharathkumar AA. J Pediatr Hematol Oncol. 2021 Apr 1;43(3):e431-e435. doi: 10.1097/MPH.0000000000001810.


Week of May 18, 2021
Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle. Moose DL, Williams-Perez S, Cafun R, Krog BL, Henry MD. J Vis Exp. 2021 Apr 27;(170). doi: 10.3791/62478.

VA-Wide, Multicenter Verification Study of the Cepheid Xpert SARS-CoV-2 Assay. Obeidat M, Frank AR, Icardi MS, Klutts JS. Acad Pathol. 2021 Apr 28;8:23742895211011911. doi: 10.1177/23742895211011911. eCollection 2021 Jan-Dec.

Experience With Pretravel Testing for SARS-CoV-2 at an Academic Medical Center. Imborek KL, Krasowski MD, Natvig P, Merrill AE, Diekema DJ, Ford BA. Acad Pathol. 2021 Apr 28;8:23742895211010247. doi: 10.1177/23742895211010247. eCollection 2021 Jan-Dec.

Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis. Kaemmer CA, Umesalma S, Maharjan CK, Moose DL, Narla G, Mott SL, Zamba GKD, Breheny P, Darbro BW, Bellizzi AM, Henry MD, Quelle DE. Sci Rep. 2021 May 13;11(1):10252. doi: 10.1038/s41598-021-89866-1.

Loss of diacylglycerol kinase ε causes thrombotic microangiopathy by impairing endothelial VEGFA signaling. Liu D, Ding Q, Dai DF, Padhy B, Nayak MK, Li C, Purvis M, Jin H, Shu C, Chauhan AK, Huang CL, Attanasio M. JCI Insight. 2021 May 10;6(9):146959. doi: 10.1172/jci.insight.146959.

Training of Pediatric Critical Care Providers in Developing Countries in Evidence Based Medicine Utilizing Remote Simulation Sessions. Padhya D, Tripathi S, Kashyap R, Alsawas M, Murthy S, Arteaga GM, Dong Y. Glob Pediatr Health. 2021 Apr 23;8:2333794X211007473. doi: 10.1177/2333794X211007473.


Week of May 11, 2021
A direct transcutaneous approach to infraorbital nerve biopsy. Yom KH, Simmons BA, Hock LE, Syed NA, Carter KD, Thurtell MJ, Shriver EM. Orbit. 2021 May 6:1-8. doi: 10.1080/01676830.2021.1920041. Online ahead of print.


Week of May 4, 2021
A Rare Inflammatory Myofibroblastic Tumor of the Mitral Valve With Systemic Embolism in a Child. Vijayakumar N, Thattaliyath B, Dundar B, Karimi M, Badheka A, Chegondi M. World J Pediatr Congenit Heart Surg. 2021 Apr 26:2150135120956629. doi: 10.1177/2150135120956629. Online ahead of print.

Aberrant Redox Biology and Epigenetic Reprogramming: Co-conspirators across Multiple Human Diseases. Domann FE, Hitchler MJ. Free Radic Biol Med. 2021 Apr 28:S0891-5849(21)00227-6. doi: 10.1016/j.freeradbiomed.2021.04.020. Online ahead of print.

The Effect of the Covid-19 Shutdown on Glycemic Testing and Control. Sharma A, Greene DN, Chambliss AB, Farnsworth CW, French D, Herman DS, Kavsak PA, Merrill AE, Margaret Lo SY, Lyon ME, Winston-McPherson G, Pearson LN, SoRelle JA, Waring AC, Schmidt RL. Clin Chim Acta. 2021 Apr 28:S0009-8981(21)00143-1. doi: 10.1016/j.cca.2021.04.018. Online ahead of print.

Continuation of Over-the-Counter Biotin Supplements in the Inpatient Setting: An Unexpected Source of Laboratory Error. Merrill AE, Malvik NM, Ford DC, Krasowski MD. J Appl Lab Med. 2021 Apr 29;6(3):735-742. doi: 10.1093/jalm/jfaa167.

Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate. Du J, Carroll RS, Steers GJ, Wagner BA, O'Leary BR, Jensen CS, Buettner GR, Cullen JJ. Antioxidants (Basel). 2021 Apr 16;10(4):614. doi: 10.3390/antiox10040614.

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Merritt N, Garcia K, Rajendran D, Lin ZY, Zhang X, Mitchell KM, Borcherding N, Fullenkamp C, Chimenti MS, Gingras AC, Harvey KF, Tanas MR. Elife. 2021 Apr 29;10:e62857. doi: 10.7554/eLife.62857. Online ahead of print.

Exclusion of Expert Contributors From Authorship Limits the Quality of Scientific Articles. Meyerholz DK, Adissu HA, Carvalho T, Atkins HM, Rissi DR, Beck AP, Ward JM, Piersigilli A. Vet Pathol. 2021 Apr 28:3009858211011943. doi: 10.1177/03009858211011943. Online ahead of print.


Week of April 27, 2021
Practical Considerations for Implementation of SARS-CoV-2 Serological Testing in the Clinical Laboratory: Experience at an Academic Medical Center. Humble RM, Merrill AE, Ford BA, Diekema DJ, Krasowski MD. Acad Pathol. 2021 Apr 7;8:23742895211002802. doi: 10.1177/23742895211002802. eCollection 2021 Jan-Dec.

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas. Desai C, Thomason J, Kohlmeyer JL, Reisetter AC, Ahirwar P, Jahanseir K, Leidinger M, Ofori-Amanfo G, Fritchie K, Velu SE, Breheny P, Quelle DE, Tanas MR. Oncotarget. 2021 Apr 13;12(8):740-755. doi: 10.18632/oncotarget.27928. eCollection 2021 Apr 13.

STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis. Zhao J, Liao Y, Miller-Little W, Xiao J, Liu C, Li X, Li X, Kang Z. J Neuroinflammation. 2021 Apr 20;18(1):98. doi: 10.1186/s12974-021-02146-7.

Stimulant use in patients presenting with psychocutaneous disorders. Richey PM, Laageide L, Swick BL. J Am Acad Dermatol. 2021 Apr 17:S0190-9622(21)00836-7. doi: 10.1016/j.jaad.2021.04.033. Online ahead of print.

Comprehensive review of chromophobe renal cell carcinoma. Garje R, Elhag D, Yasin HA, Acharya L, Vaena D, Dahmoush L. Crit Rev Oncol Hematol. 2021 Apr;160:103287. doi: 10.1016/j.critrevonc.2021.103287. Epub 2021 Mar 19.


Week of April 20, 2021
Introduction to the Special Issue on 'Epigenetics and Redox Signaling'. Domann FE, Hitchler MJ. Free Radic Biol Med. 2021 Apr 13:S0891-5849(21)00219-7. doi: 10.1016/j.freeradbiomed.2021.04.015. Online ahead of print.

Ki-67 Proliferation Index Assessment in Gastroenteropancreatic Neuroendocrine Tumors by Digital Image Analysis With Stringent Case and Hotspot Level Concordance Requirements. Boukhar SA, Gosse MD, Bellizzi AM, Rajan Kd A. Am J Clin Pathol. 2021 Apr 13:aqaa275. doi: 10.1093/ajcp/aqaa275. Online ahead of print.


Week of April 13, 2021
Response to: An alternative hypothesis for why exposure to static magnetic and electric fields treats type 2 diabetes. Carter CS, Huang S, Searby C, Cassaidy B, Miller M, Grzesik W, Piorczynski TB, Pak TK, Walsh S, Acevedo M, Zhang Q, Mapuskar K, Milne G, Hinton AO Jr, Guo DF, Weiss RM, Bradberry K, Taylor EB, Rauckhorst A, Dick D, Akurathi V, Falls-Hubert K, Wagner B, Carter W, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Am J Physiol Endocrinol Metab. 2021 Apr 12. doi: 10.1152/ajpendo.00119.2021. Online ahead of print.

Counterpoint regarding an alternative hypothesis for why exposure to static magnetic and electric fields treat type 2 diabetes. Carter CS, Huang S, Searby C, Cassaidy B, Miller M, Grzesik W, Piorczynski TB, Pak TK, Walsh S, Acevedo M, Zhang Q, Mapuskar K, Milne G, Hinton AO Jr, Guo DF, Weiss RM, Bradberry K, Taylor EB, Rauckhorst A, Dick D, Akurathi V, Falls-Hubert K, Wagner B, Carter W, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Am J Physiol Endocrinol Metab. 2021 Apr 12. doi: 10.1152/ajpendo.00110.2021. Online ahead of print.

Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donors. Vickers MA, Sariol A, Leon J, Ehlers A, Locher AV, Dubay KA, Collins L, Voss D, Odle AE, Holida M, Merrill AE, Perlman S, Knudson CM. Transfusion. 2021 Apr 8. doi: 10.1111/trf.16401. Online ahead of print.

Prefusion F-Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus. Stephens LM, Ross KA, Waldstein KA, Legge KL, McLellan JS, Narasimhan B, Varga SM. J Immunol. 2021 Apr 7:ji2100018. doi: 10.4049/jimmunol.2100018. Online ahead of print.

Dynamics of Humoral Immunity Post COVID Vaccination – A Case Report. Jackson JB, Dempewolf S, Johnson AL, Van Ert H, Maury W. Clin Rev & Cases 2021; 3(1): 1-2.

AP-2alpha Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer. Beck AC, Cho E, White JR, Paemka L, Li T, Gu VW, Thompson DT, Koch KE, Franke C, Gosse M, Wu VT, Landers SR, Pamatmat AJ, Kulak MV, Weigel RJ. Mol Cancer Res. 2021 Mar 22;molcanres.MCR-20-0867-E.2020. doi: 10.1158/1541-7786.MCR-20-0867. Online ahead of print.


Week of April 6, 2021
Vitamin D Level Stability in Dystrophinopathy Patients on Vitamin D Supplementation. Vather-Wu N, Krasowski MD, Mathews KD, Shibli-Rahhal A. J Neuromuscul Dis. 2021 Apr 1. doi: 10.3233/JND-200625. Online ahead of print.

A systematic review of adherence to physical activity interventions in individuals with type 2 diabetes. MacDonald CS, Ried-Larsen M, Soleimani J, Alsawas M, Lieberman DE, Ismail AS, Serafim LP, Yang T, Prokop L, Joyner M, Murad MH, Barwise A. Diabetes Metab Res Rev. 2021 Mar 8:e3444. doi: 10.1002/dmrr.3444. Online ahead of print.

Melanoma Brain Metastases in the Era of Targeted Therapy and Checkpoint Inhibitor Therapy. Rieth JM, Swami U, Mott SL, Zanaty M, Henry MD, Bossler AD, Greenlee JD, Zakharia Y, Vanneste M, Jennings B, Milhem MM. Cancers (Basel). 2021 Mar 24;13(7):1489. doi: 10.3390/cancers13071489.

V-type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells. Li X, Villacreses R, Thornell IM, Noriega J, Mather S, Brommel CM, Lu L, Zabner A, Ehler A, Meyerholz DK, Stoltz DA, Zabner J. Am J Respir Cell Mol Biol. 2021 Mar 31. doi: 10.1165/rcmb.2020-0349OC. Online ahead of print.

Commentary on Unexpected Presence of an Unusual Opioid in a Patient with Chronic Pain. Krasowski MD. Clin Chem. 2021 Mar 31;67(4):600-601. doi: 10.1093/clinchem/hvaa320. No abstract available.

Perilipin2 down-regulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria. Mishra A, Liu S, Promes J, Harata M, Sivitz WI, Fink BD, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens SB, King TH, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum JA, Imai Y. JCI Insight. 2021 Mar 30:144341. doi: 10.1172/jci.insight.144341. Online ahead of print.


Week of March 30, 2021
Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice. Xu H, Li H, Liu D, Wen W, Xu M, Frank JA, Chen J, Zhu H, Grahame NJ, Luo J. Front Pharmacol. 2021 Mar 9;12:614396. doi: 10.3389/fphar.2021.614396. eCollection 2021.

A Surgical Window Trial Evaluating Medroxyprogesterone Acetate with or without Entinostat in Patients with Endometrial Cancer and Validation of Biomarkers of Cellular Response. Duska LR, Filiaci VL, Walker JL, Holman LL, Hill EK, Moore RG, Ring KL, Pearl ML, Muller CY, Kushnir CL, Lankes HA, Samuelson MI, Carrick KS, Rajan A, Rodgers WH, Kohn EC, Piekarz R, Leslie KK. Clin Cancer Res. 2021 Mar 25. doi: 10.1158/1078-0432.CCR-20-4618. Online ahead of print.

Palliative care consultation in patients with Staphylococcus aureus bacteremia. Kobayashi T, Salinas JL, Ten Eyck P, Chen B, Ando T, Inagaki K, Alsuhaibani M, Auwaerter PG, Molano I, Diekema DJ. Palliat Med. 2021 Mar 24:269216321999574. doi: 10.1177/0269216321999574. Online ahead of print.

Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium. van de Locht M, Donkervoort S, de Winter JM, Conijn S, Begthel L, Kusters B, Mohassel P, Hu Y, Medne L, Quinn C, Moore SA, Foley AR, Seo G, Hwee DT, Malik FI, Irving T, Ma W, Granzier H, Kamsteeg EJ, Immadisetty K, Kekenes-Huskey P, Pinto JR, Voermans N, Bönnemann CG, Ottenheijm CA. J Clin Invest. 2021 Mar 23:145700. doi: 10.1172/JCI145700. Online ahead of print.

Comprehensive review of chromophobe renal cell carcinoma. Garje R, Elhag D, Yasin HA, Acharya L, Vaena D, Dahmoush L. Crit Rev Oncol Hematol. 2021 Mar 19;160:103287. doi: 10.1016/j.critrevonc.2021.103287. Online ahead of print.


Week of March 23, 2021
A mutilating, persistent lip ulcer as a presenting sign of oral mycosis fungoides with large cell transformation. Robinson CL, Sethupathi SK, Fairley JA, Link BK, Liu V. JAAD Case Rep. 2021 Feb 3;10:14-17. doi: 10.1016/j.jdcr.2021.01.023. eCollection 2021 Apr.

Frozen Section Quality Assurance. Laakman JM, Chen SJ, Lake KS, Blau JL, Rajan DA, Samuelson MI, Robinson RA. Am J Clin Pathol. 2021 Mar 17:aqaa259. doi: 10.1093/ajcp/aqaa259. Online ahead of print.

COVID-19 Convalescent Plasma; Time for "Goal Directed Therapy"? Knudson CM, Jackson JB. Transfusion. 2021 Mar 15. doi: 10.1111/trf.16381. Online ahead of print. No abstract available.


Week of March 16, 2021
Therapeutic Drug Monitoring of Second- and Third-Generation Antiepileptic Drugs: Insights From a College of American Pathologists Proficiency Testing Survey. Krasowski MD, Long TA, Snozek CLH, Dizon A, Magnani B, Melanson SEF. Arch Pathol Lab Med. 2021 Mar 15. doi: 10.5858/arpa.2020-0562-CP. Online ahead of print.

Research Relevant Background Lesions and Conditions: Ferrets, Dogs, Swine, Sheep, and Goats. Helke KL, Meyerholz DK, Beck AP, Burrough ER, Derscheid RJ, Löhr C, McInnes EF, Scudamore CL, Brayton CF. ILAR J. 2021 Mar 13:ilab005. doi: 10.1093/ilar/ilab005. Online ahead of print.

Severe Acute Respiratory Syndrome Coronavirus 2-Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells. Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. J Infect Dis. 2021 Mar 3;223(5):785-795. doi: 10.1093/infdis/jiaa753.


Week of March 9, 2021
Distinct properties of Ca2+ efflux from brain, heart and liver mitochondria: The effects of Na+, Li+ and the mitochondrial Na+/Ca2+ exchange inhibitor CGP37157. Rysted JE, Lin Z, Walters GC, Rauckhorst AJ, Noterman M, Liu G, Taylor EB, Strack S, Usachev YM. Cell Calcium. 2021 Feb 22;96:102382. doi: 10.1016/j.ceca.2021.102382. Online ahead of print.

Permissive Modulation of Sphingosine-1-Phosphate-Enhanced Intracellular Calcium on BKCa Channel of Chromaffin Cells. Wu AZ, Ohn TL, Shei RJ, Wu HF, Chen YC, Lee HC, Dai DF, Wu SN. Int J Mol Sci. 2021 Feb 22;22(4):2175. doi: 10.3390/ijms22042175.

A 52-Year-Old Man With Uveitis and Altered Mental Status. Kobayashi T, Amram AL, Gehrs K, Diekema D, Barker J. Clin Infect Dis. 2021 Mar 1;72(5):873-875. doi: 10.1093/cid/ciaa051. No abstract available.

Presacral neuroendocrine tumors associated with the Currarino syndrome. Scott AT, Tessmann JB, Braun T, Brown B, Breheny PJ, Darbro BW, Bellizzi AM, Dillon JS, O'Dorisio TM, Alderson A, Bennett B, Bernat JA, Metz DC, Howe JR. Am J Med Genet A. 2021 Mar 1. doi: 10.1002/ajmg.a.62145. Online ahead of print.

Human BM-MSC secretome enhances human granulosa cell proliferation and steroidogenesis and restores ovarian function in primary ovarian insufficiency mouse model. Park HS, Chugh RM, El Andaloussi A, Hobeika E, Esfandyari S, Elsharoud A, Ulin M, Garcia N, Bilal M, Al-Hendy A. Sci Rep. 2021 Feb 25;11(1):4525. doi: 10.1038/s41598-021-84216-7.

Conversion Rates to COVID-19 Infection Among Exposed Healthcare Workers. Jackson JB, Salinas JL, Heineman J, Hartley P. Microbiol Infect Dis. 2021; 5(1): 1-3.


Week of March 2, 2021
MANF Protects Pancreatic Acinar Cells Against Alcohol-induced Endoplasmic Reticulum Stress and Cellular injury. Wu H, Li H, Wen W, Wang Y, Xu H, Xu M, Frank JA, Wei W, Luo J. J Hepatobiliary Pancreat Sci. 2021 Feb 28. doi: 10.1002/jhbp.928. Online ahead of print.

Ethanol Biomarker Testing and Challenges: Lessons Learned From a College of American Pathologists Proficiency Testing Survey. Snozek CLH, Souers R, Dizon A, Magnani B, Krasowski MD. Arch Pathol Lab Med. 2021 Feb 26. doi: 10.5858/arpa.2020-0699-CP. Online ahead of print.

A Multi-Center Outbreak of Candida tropicalis Bloodstream Infections Associated with Contaminated Hemodialysis Machine Prime Buckets. Boyce JM, Dumigan DG, Havill NL, Hollis RJ, Pfaller MA, Moore BA. Am J Infect Control. 2021 Feb 22:S0196-6553(21)00090-0. doi: 10.1016/j.ajic.2021.02.014. Online ahead of print.

Markers of Follicular Helper T Cells Are Occasionally Expressed in T-Cell or Histiocyte-Rich Large B-Cell Lymphoma, Classic Hodgkin Lymphoma, and Atypical Paracortical HyperplasiaA Diagnostic Pitfall For T-Cell Lymphomas of T Follicular Helper Origin. Abukhiran I, Syrbu SI, Holman CJ. Am J Clin Pathol. 2021 Feb 24:aqaa249. doi: 10.1093/ajcp/aqaa249. Online ahead of print.


Week of February 23, 2021
Education Case: Hereditary Thrombophilia With Double Heterozygous Factor V Leiden and Factor II c.*97G>A Mutations. Abukhiran I, Jasser J, Bhagavathi S. Acad Pathol. 2021 Feb 7;8:2374289521990788. doi: 10.1177/2374289521990788. eCollection 2021 Jan-Dec.

SARS-CoV-2 Infection during Pregnancy in a Rural Midwest All-delivery Cohort and Associated Maternal and Neonatal Outcomes. Steffen HA, Swartz SR, Jackson JB, Kenne KA, Ten Eyck PP, Merryman AS, Castaneda CN, Marsden K, Maxwell T, Merrill AE, Krasowski MD, Rysavy MB. Am J Perinatol. 2021 Feb 21. doi: 10.1055/s-0041-1723938. Online ahead of print.

Data on the activation and utilization of an electronic health record patient portal in an adult inpatient population at an academic medical center. Allard CT, Krasowski MD. Data Brief. 2021 Jan 30;35:106806. doi: 10.1016/j.dib.2021.106806. eCollection 2021 Apr.


Week of February 16, 2021
Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate. Cramer-Morales KL, Heer CD, Mapuskar KA, Domann FE. J Exp Pathol (Wilmington). 2020;1(2):60-70. Epub 2020 Dec 9.

DMPK mRNA Expression in Human Brain Tissue Throughout the Lifespan. Langbehn KE, Carlson-Stadler Z, van der Plas E, Hefti MM, Dawson JD, Moser DJ, Nopoulos PC. Neurol Genet. 2020 Dec 21;7(1):e537. doi: 10.1212/NXG.0000000000000537. eCollection 2021 Feb.

Temporal Trends of Candidemia Incidence Rates and Potential Contributions of Infection Control Initiatives over 18 Years within the US Veteran Health Administration System: A Joinpoint Time-Series Analysis. Suzuki H, Perencevich EN, Diekema DJ, Livorsi DJ, Nair R, Kralovic SM, Roselle GA, Goto M. Clin Infect Dis. 2021 Feb 10:ciab105. doi: 10.1093/cid/ciab105. Online ahead of print.

A Functionally Distinct CXCR3+/IFN-γ+/IL-10+ Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells. Brate AA, Boyden AW, Jensen IJ, Badovinac VP, Karandikar NJ. J Immunol. 2021 Feb 8:ji2001143. doi: 10.4049/jimmunol.2001143. Online ahead of print.


Week of February 9, 2021
Decidualization score identifies an endometrial dysregulation in samples from women with recurrent pregnancy losses and unexplained infertility. Dambaeva S, Bilal M, Schneiderman S, Germain A, Fernandez E, Kwak-Kim J, Beaman K, Coulam C. J F&S Reports, 2020, doi; 10.1016/j.xfre.2020.12.004.

RNA-seq Reveals Differences in Expressed Tumor Mutational Burden in Colorectal and Endometrial Cancer With and Without Defective DNA Mismatch Repair. DiGuardo MA, Davila JI, Jackson RA, Nair AA, Fadra N, Minn KT, Atiq MA, Zarei S, Blommel JH, Knight SM, Jen J, Eckloff BW, Voss JS, Rumilla KM, Kerr SE, Lam-Himlin DM, Bellizzi AM, Graham RP, Kipp BR, Jenkins RB, Halling KC. J Mol Diagn. 2021 Feb 4:S1525-1578(21)00029-5. doi: 10.1016/j.jmoldx.2021.01.008. Online ahead of print.

γδ T cells burst malaria's bubble. Lefebvre MN, Harty JT. Nat Immunol. 2021 Feb 5. doi: 10.1038/s41590-021-00879-4. Online ahead of print. No abstract available.

Tissue-Resident Memory T Cells in the Lungs Protect against Acute Respiratory Syncytial Virus Infection. Luangrath MA, Schmidt ME, Hartwig SM, Varga SM. Immunohorizons. 2021 Feb 3;5(2):59-69. doi: 10.4049/immunohorizons.2000067.

A case of idiopathic acquired leukonychia totalis in a 17-year-old boy. Freeman SC, Dick MK, Abid R, Tabatabai TM, Berrebi KG, Stone MS, Powers JG. Pediatr Dermatol. 2021 Feb 3. doi: 10.1111/pde.14531. Online ahead of print.

Basal Cell Adenoma and Basal Cell Adenocarcinoma. Robinson RA. Surg Pathol Clin. 2021 Mar;14(1):25-42. doi: 10.1016/j.path.2020.09.005. Epub 2021 Jan 5.


Week of February 2, 2021
How Can Routine Clinical Laboratories Keep Up with the Opioid Crisis? Snozek CLH, Baskin LB, Boyd JM, Kelly BN, Krasowski MD, Sadrzadeh SMH, Tacker DH. Clin Chem. 2021 Jan 30;67(2):338-344. doi: 10.1093/clinchem/hvaa305. No abstract available.

Is Unplanned PICU Readmission a Proper Quality Indicator? A Systematic Review and Meta-analysis. Prutsky GJ, Padhya D, Ahmed AT, Almasri J, Farah WH, Prokop LJ, Murad MH, Alsawas M. Hosp Pediatr. 2021 Jan 27:hpeds.2020-0192. doi: 10.1542/hpeds.2020-0192. Epub ahead of print.

NK Cell-Derived IL-10 Supports Host Survival during Sepsis. Jensen IJ, McGonagill PW, Butler NS, Harty JT, Griffith TS, Badovinac VP. J Immunol. 2021 Jan 29:ji2001131. doi: 10.4049/jimmunol.2001131. Online ahead of print.

TOR Signaling Pathway in Cardiac Aging and Heart Failure. Daneshgar N, Rabinovitch PS, Dai DF. Biomolecules. 2021 Jan 27;11(2):168. doi: 10.3390/biom11020168.

Rapid Validation of Whole-Slide Imaging for Primary Histopathology Diagnosis. Samuelson MI, Chen SJ, Boukhar SA, Schnieders EM, Walhof ML, Bellizzi AM, Robinson RA, Rajan Kd A. Am J Clin Pathol. 2021 Jan 29:aqaa280. doi: 10.1093/ajcp/aqaa280. Online ahead of print.


Week of January 26, 2021
Congenital Myenteric Hypoganglionosis. Kapur RP, Bellizzi AM, Bond S, Chen H, Han JS, LeGallo RD, Midgen C, Poulin AA, Uddin N, Warren M, Velázquez Vega JE, Zuppan CW. Am J Surg Pathol. 2021 Jan 22. doi: 10.1097/PAS.0000000000001670. Online ahead of print.

COVID-19 Research Agenda for Healthcare Epidemiology. Mody L, Akinboyo IC, Babcock HM, Bischoff WE, Cheng VC, Chiotos K, Claeys KC, Coffey KC, Diekema DJ, Donskey CJ, Ellingson KD, Gilmartin HM, Gohil SK, Harris AD, Keller SC, Klein EY, Krein SL, Kwon JH, Lauring AS, Livorsi DJ, Lofgren ET, Merrill K, Milstone A, Monsees EA, Morgan DJ, Perri LP, Pfeiffer CD, Rock C, Saint S, Sickbert-Bennett E, Skelton F, Suda KJ, Talbot TR, Vaughn VM, Weber DJ, Wiemken TL, Yassin MH, Ziegler MJ, Anderson DJ; SHEA Research Committee. Infect Control Hosp Epidemiol. 2021 Jan 25:1-81. doi: 10.1017/ice.2021.25. Online ahead of print.

Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy. Petronek MS, Stolwijk JM, Murray SD, Steinbach EJ, Zakharia Y, Buettner GR, Spitz DR, Allen BG. Redox Biol. 2021 Jan 16:101864. doi: 10.1016/j.redox.2021.101864. Online ahead of print.

Planet of the Vapes. Johnson Ava L, Jackson J Brooks. J Med - Clin Res & Rev. 2021; 5(1): 1-3.

Let’s not sugarcoat it: COVID-19 preys on the obese. Johnson A, Jackson JB. Iowa Medicine 2020, Q4:24-25.

Sexually Transmitted Infections Among College Students. Johnson A, Jackson JB. Microbiol Infect Dis. 2021; 5(1): 1-4.


Week of January 19, 2021
Combination therapies for MPNSTs targeting RABL6A-RB1 signaling. Kohlmeyer JL, Gordon DJ, Tanas MR, Dodd RD, Monga V, Darbro BW, Quelle DE. Oncotarget. 2021 Jan 5;12(1):10-14. doi: 10.18632/oncotarget.27862. eCollection 2021 Jan 5.

The Significance and Clinical Outcome of Lymphocytic Duodenosis in Children: Mayo Clinic Experience and Systematic Review. Devara J, Alsawas M, Larson JJ, Mounajjed T, Murray JA, Absah I. J Pediatr Gastroenterol Nutr. 2021 Feb 1;72(2):288-293. doi: 10.1097/MPG.0000000000002942.

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent. Cheng Y, Borcherding N, Ogunsakin A, Lemke-Miltner CD, Gibson-Corley KN, Rajan A, Choi AB, Wongpattaraworakul W, Chan CHF, Salem AK, Weiner GJ, Simons AL. Sci Rep. 2021 Jan 15;11(1):1535. doi: 10.1038/s41598-020-80957-z.

The epigenetic and morphogenetic effects of molecular oxygen and its derived reactive species in development. Hitchler MJ, Domann FE. Free Radic Biol Med. 2021 Jan 12:S0891-5849(21)00014-9. doi: 10.1016/j.freeradbiomed.2021.01.008. Online ahead of print.

Metastatic Squamous Cell Carcinoma of the Tonsil Mimicking Choroidal Melanoma. Binkley EM, Sampson AD, Syed NA, Boldt HC. Ocul Oncol Pathol. 2020 Dec;6(6):405-409. doi: 10.1159/000510288. Epub 2020 Oct 16.

Making sense of missense variants in TTN-related congenital myopathies. Rees M, Nikoopour R, Fukuzawa A, Kho AL, Fernandez-Garcia MA, Wraige E, Bodi I, Deshpande C, Özdemir Ö, Daimagüler HS, Pfuhl M, Holt M, Brandmeier B, Grover S, Fluss J, Longman C, Farrugia ME, Matthews E, Hanna M, Muntoni F, Sarkozy A, Phadke R, Quinlivan R, Oates EC, Schröder R, Thiel C, Reimann J, Voermans N, Erasmus C, Kamsteeg EJ, Konersman C, Grosmann C, McKee S, Tirupathi S, Moore SA, Wilichowski E, Hobbiebrunken E, Dekomien G, Richard I, Van den Bergh P, Domínguez-González C, Cirak S, Ferreiro A, Jungbluth H, Gautel M. Acta Neuropathol. 2021 Jan 15. doi: 10.1007/s00401-020-02257-0. Online ahead of print.

CLIA Laboratory Testing for Facioscapulohumeral Dystrophy (FSHD): A Retrospective Analysis. Rieken A, Bossler AD, Mathews KD, Moore SA. Neurology. 2020 Dec 21:10.1212/WNL.0000000000011412. doi: 10.1212/WNL.0000000000011412. Online ahead of print.

Sublingual Estradiol Is Associated with Higher Estrone Concentrations than Transdermal or Injectable Preparations in Transgender Women and Gender Nonbinary Adults. Cirrincione LR, Winston McPherson G, Rongitsch J, Sadilkova K, Drees JC, Krasowski MD, Dickerson JA, Greene DN. LGBT Health. 2021 Jan 13. doi: 10.1089/lgbt.2020.0249. Online ahead of print.

Utility of Flow Cytometry and Fluorescence In Situ Hybridization in Follow-up Monitoring of Plasma Cell Myeloma. Chopra S, Dunham T, Syrbu SI, Karandikar NJ, Darbro BW, Holman CJ. Am J Clin Pathol. 2021 Jan 13:aqaa224. doi: 10.1093/ajcp/aqaa224. Online ahead of print.

Evaluation of Synergistic Activity of Isavuconazole or Voriconazole plus Anidulafungin and the Occurrence and Genetic Characterisation of Candida auris Detected in a Surveillance Program. Pfaller MA, Messer SA, Deshpande LM, Rhomberg PR, Utt EA, Castanheira M. Antimicrob Agents Chemother. 2021 Jan 11:AAC.02031-20. doi: 10.1128/AAC.02031-20. Online ahead of print.


Week of January 12, 2021
Spreading violaceous neck plaques in a fatigued man. Thompson HJ, Patrick A, Liu V. Clin Exp Dermatol. 2021 Jan 10. doi: 10.1111/ced.14545. Online ahead of print. No abstract available.

Implementation and Assessment of an Effective, Novel, Student-Centered, Remotely Accessible, Dermatology Education Program: A Prospective Cohort Study. Poggemiller AM, Kreiter C, Naridze R, Melrose E, Fenton P, Wanat KA, Liu V. J Am Acad Dermatol. 2021 Jan 7:S0190-9622(21)00078-5. doi: 10.1016/j.jaad.2021.01.011. Online ahead of print. No abstract available.

Two cases of brand-specific albumin sensitivity in patients receiving regular therapeutic plasma exchange. Rogers KJ, Schlueter AJ. Transfus Apher Sci. 2021 Jan 2:103047. doi: 10.1016/j.transci.2020.103047. Online ahead of print.

Unique imaging appearance of neurosarcoidosis as a solitary cystic mass with mural enhancement. Bathla G, Kandemirli SG, Gupta S, Agarwal A. Surg Neurol Int. 2020 Dec 22;11:463. doi: 10.25259/SNI_830_2020. eCollection 2020.

Refractory infantile high-grade glioma containing TRK-fusion responds to larotrectinib. Waters TW, Moore SA, Sato Y, Dlouhy BJ, Sato M. Pediatr Blood Cancer. 2021 Jan 5:e28868. doi: 10.1002/pbc.28868. Online ahead of print. No abstract available.

Not All Küttner Tumors Are IgG4-Related Disease (IgG4-RD). Marcus KS, Hoffman HT, Rajan Kd A. Head Neck Pathol. 2021 Jan 4. doi: 10.1007/s12105-020-01268-3. Online ahead of print.

Microvascular Injury in the Brains of Patients with Covid-19. Lee MH, Perl DP, Nair G, Li W, Maric D, Murray H, Dodd SJ, Koretsky AP, Watts JA, Cheung V, Masliah E, Horkayne-Szakaly I, Jones R, Stram MN, Moncur J, Hefti M, Folkerth RD, Nath A.Lee MH, et al. N Engl J Med. 2020 Dec 30. doi: 10.1056/NEJMc2033369. Online ahead of print.N Engl J Med. 2020. No abstract available.

Increased cerebral mitochondrial dysfunction and reactive oxygen species with cardiopulmonary bypass. Volk LE, Mavroudis CD, Ko T, Hallowell T, Delso N, Roberts AL, Starr J, Landis W, Lin Y, Hefti M, Morgan RW, Melchior RW, Rosenthal TM, Chappell A, Fisher D, Dreher M, Licht DJ, Chen J, Gaynor JW, Mascio CE, Kilbaugh TJ.Volk LE, et al. Eur J Cardiothorac Surg. 2020 Dec 24:ezaa439. doi: 10.1093/ejcts/ezaa439. Online ahead of print. Eur J Cardiothorac Surg. 2020.


Week of January 5, 2021
Triphenylphosphonium derivatives disrupt metabolism and inhibit melanoma growth in vivo when delivered via a thermosensitive hydrogel. Kloepping KC, Kraus AS, Hedlund DK, Gnade CM, Wagner BA, McCormick ML, Fath MA, Seol D, Lim TH, Buettner GR, Goswami PC, Pigge FC, Spitz DR, Schultz MK. PLoS One. 2020 Dec 30;15(12):e0244540. doi: 10.1371/journal.pone.0244540. eCollection 2020.


Week of December 29, 2020
Human Commensal Prevotella histicola Ameliorates Disease as Effectively as Interferon-Beta in the Experimental Autoimmune Encephalomyelitis. Shahi SK, Jensen SN, Murra AC, Tang N, Guo H, Gibson-Corley KN, Zhang J, Karandikar NJ, Murray JA, Mangalam AK. Front Immunol. 2020 Dec 11;11:578648. doi: 10.3389/fimmu.2020.578648. eCollection 2020.

CLL dedifferentiation to clonally related myeloid cells. Dong Q, Xiu Y, Bossler A, Syrbu S, Wang H, Xue W, Zhao J, Li Q, Jin M, Wang L, Boyce B, Sakr H, Ansari MQ, Zhao C. Blood Adv. 2020 Dec 22;4(24):6169-6174. doi: 10.1182/bloodadvances.2020002726.


Week of December 22, 2020
Assessment of Gadobutrol Safety in Combination with Ionizing Radiation Using a Preclinical MRI-Guided Radiotherapy Model. Petronek MS, Steinbach EJ, Kalen AL, Builta ZJ, Callaghan CM, Hyer DE, Spitz DR, Flynn RT, Buatti JM, Magnotta VA, Zepeda-Orozco D, St-Aubin JJ, Allen BG. Radiat Res. 2020 Dec 21. doi: 10.1667/RADE-20-00199.1. Online ahead of print.

Nanoparticle vaccines against respiratory syncytial virus. Stephens LM, Varga SM. Future Virol. 2020 Nov;15(11):763-778. doi: 10.2217/fvl-2020-0174. Epub 2020 Nov 30.

Paraneoplastic leukemoid reaction: Case report and review of the literature. Abukhiran I, Mott SL, Bellizzi AM, Boukhar SA. Pathol Res Pract. 2020 Nov 25;217:153295. doi: 10.1016/j.prp.2020.153295. Online ahead of print.

Educational Case: Necrotizing and Crescentic Glomerulonephritis With Anti-Glomerular Basement Membrane Antibodies (Anti-Gbm). Peyton N, Rastogi P. Acad Pathol. 2020 Dec 4;7:2374289520975166. doi: 10.1177/2374289520975166. eCollection 2020 Jan-Dec.

Challenges and Opportunities for the Veterinary Pathologist in Biomedical Research. Hoenerhoff MJ, Meyerholz DK, Brayton C, Beck AP. Vet Pathol. 2020 Dec 17:300985820974005. doi: 10.1177/0300985820974005. Online ahead of print.

Pten-NOLC1 fusion promotes cancers involving MET and EGFR signalings. Luo JH, Liu S, Tao J, Ren BG, Luo K, Chen ZH, Nalesnik M, Cieply K, Ma T, Cheng SY, Chen Q, Michalopoulos GK, Nelson JB, Bhargava R, Zhang J, Ma D, Jarrard D, Pennathur A, Luketich JD, DeFranco DB, Monga SP, Tseng G, Yu YP. Oncogene. 2020 Dec 15. doi: 10.1038/s41388-020-01582-8. Online ahead of print.

Impact of routine mismatch repair screening on genetic counseling and surgical management in colorectal cancer patients. Koch KE, Goffredo P, Hrabe JE, Gribovskaja-Rupp I, Snow AN, Bellizzi AM, Kapadia MR. Am J Surg. 2020 Dec 9:S0002-9610(20)30795-9. doi: 10.1016/j.amjsurg.2020.12.017. Online ahead of print.


Week of December 15, 2020
No Longer Benign: Altered Mental Status and Apparent Coagulopathy in a Woman with Monoclonal Gammopathy of Undetermined Significance. Parsons MG, Halvorson TS, Isaacson AL, Blau JL, Merrill AE. J Appl Lab Med. 2020 Dec 13:jfaa184. doi: 10.1093/jalm/jfaa184. Online ahead of print.

Disparities and Bias in Pathology and Laboratory Medicine. Klutts JS, Genzen JR. J Appl Lab Med. 2020 Dec 12:jfaa205. doi: 10.1093/jalm/jfaa205. Online ahead of print.

Influence of Clinical Information on the Histopathological Diagnosis of Mycosis Fungoides: a Follow-up Study Using Scanned Slide Image Review. Dittmer M, Brown-Joel ZO, Smith HL, Liu V. J Cutan Pathol. 2020 Dec 9. doi: 10.1111/cup.13934. Online ahead of print. No abstract available.

MANF is neuroprotective against ethanol-induced neurodegeneration through ameliorating ER stress. Wang Y, Wen W, Li H, Clementino M, Xu H, Xu M, Ma M, Frank J, Luo J. Neurobiol Dis. 2020 Dec 6;148:105216. doi: 10.1016/j.nbd.2020.105216. Online ahead of print.

Bartonella osteomyelitis versus vertebral sarcoidosis: A tale of two cases. Soni N, Gupta S, Pillenahalli Maheshwarappa R, Priya S, Bathla G. Neuroradiol J. 2020 Dec 9:1971400920978433. doi: 10.1177/1971400920978433. Online ahead of print.

Influenza-Specific Lung-Resident Memory CD8+ T Cells. van de Wall S, Badovinac VP, Harty JT. Cold Spring Harb Perspect Biol. 2020 Dec 7:a037978. doi: 10.1101/cshperspect.a037978. Online ahead of print.

The Postmortem Features of Mucormycosis. Halvorson TS, Isaacson AL, Ford BA, Firchau DJ. Acad Forensic Pathol. 2020 Jun;10(2):72-80. doi: 10.1177/1925362120960918. Epub 2020 Nov 25.Acad Forensic Pathol. 2020.

Congenitally corrected transposition of the great arteries. Halvorson T,Blau J, Firchau D. Cardiovasc Pathol. 2021 Jan-Feb;50:107267. doi: 10.1016/j.carpath.2020.107267. Epub 2020 Aug 18.Cardiovasc Pathol. 2021.


Week of December 8, 2020
SARS-CoV-2-induced immune activation and death of monocyte-derived human macrophages and dendritic cells. Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. J Infect Dis. 2020 Dec 5:jiaa753. doi: 10.1093/infdis/jiaa753. Online ahead of print.

Zebra-like bodies in COVID-19: is phospholipidosis evidence of hydroxychloroquine induced acute kidney injury? Obeidat M, Isaacson AL, Chen SJ, Ivanovic M, Holanda D. Ultrastruct Pathol. 2020 Dec 4:1-5. doi: 10.1080/01913123.2020.1850966. Online ahead of print.

Effect of bacterial contamination in bile on pancreatic cancer cell survival. Shrader HR, Miller AM, Tomanek-Chalkley A, McCarthy A, Coleman KL, Ear PH, Mangalam AK, Salem AK, Chan CHF. Surgery. 2020 Oct 22:S0039-6060(20)30632-2. doi: 10.1016/j.surg.2020.09.029. Online ahead of print.

Magnetic resonance imaging (MRI) of pharmacological ascorbate-induced iron redox state as a biomarker in subjects undergoing radio-chemotherapy. Cushing CM, Petronek MS, Bodeker KL, Vollstedt S, Brown HA, Opat E, Hollenbeck NJ, Shanks T, Berg DJ, Smith BJ, Smith MC, Monga V, Furqan M, Howard MA, Greenlee JD, Mapuskar KA, St-Aubin J, Flynn RT, Cullen JJ, Buettner GR, Spitz DR, Buatti JM, Allen BG, Magnotta VA. Redox Biol. 2020 Nov 19;38:101804. doi: 10.1016/j.redox.2020.101804. Online ahead of print.


Week of December 1, 2020
Reproductive Endocrinology Reference Intervals for Transgender Men on Stable Hormone Therapy. Greene DN, Schmidt RL, Winston-McPherson G, Rongitsch J, Imborek KL, Dickerson JA, Drees JC, Humble RM, Nisly N, Dole NJ, Dane SK, Frerichs J, Krasowski MD. J Appl Lab Med. 2020 Nov 26:jfaa169. doi: 10.1093/jalm/jfaa169. Online ahead of print.


Week of November 24, 2020
The Association of ABO blood groups and diseases including COVID-19. Johnson A, Jackson JB. J Med Clin Res & Rev 2020;4: 1-4.

Does common cold coronavirus infection protect against severe SARS-CoV2 disease? Meyerholz DK, Perlman S. J Clin Invest. 2020 Nov 20:144807. doi: 10.1172/JCI144807. Online ahead of print.

The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis. Song J, Merrill RA, Usachev AY, Strack S. J Biol Chem. 2020 Nov 16:jbc.RA120.016210. doi: 10.1074/jbc.RA120.016210. Online ahead of print.

Association of gallbladder hyperkinesia with acalculous chronic cholecystitis: A case-control study. Pillenahalli Maheshwarappa R, Menda Y, Graham MM, Boukhar SA, Zamba GKD, Samuel I. Surgery. 2020 Nov;168(5):800-808. doi: 10.1016/j.surg.2020.06.005. Epub 2020 Jul 9.


Week of November 17, 2020
Clinical laboratory validation of the MCL35 assay for molecular risk stratification of mantle cell lymphoma. Ramsower CA, Maguire A, Robetorye RS, Feldman AL, Syrbu SI, Rosenthal AC, Rimsza LM. J Hematop. 2020 Oct 13;13(4):231-238. doi: 10.1007/s12308-020-00418-4. eCollection 2020 Dec.

Intestinal Dysbiosis in, and Enteral Bacterial Therapies for, Systemic Autoimmune Diseases. Marietta E, Mangalam AK, Taneja V, Murray JA. Front Immunol. 2020 Oct 28;11:573079. doi: 10.3389/fimmu.2020.573079. eCollection 2020.

IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation. Renavikar PS, Sinha S, Brate AA, Borcherding N, Crawford MP, Steward-Tharp SM, Karandikar NJ. Front Immunol. 2020 Oct 28;11:568630. doi: 10.3389/fimmu.2020.568630. eCollection 2020.

Sepsis impedes EAE disease development and diminishes autoantigen-specific naïve CD4 T cells. Jensen IJ, Jensen SN, Sjaastad FV, Gibson-Corley KN, Dileepan T, Griffith TS, Mangalam AK, Badovinac VP. Elife. 2020 Nov 16;9:e55800. doi: 10.7554/eLife.55800. Online ahead of print.


Week of November 10, 2020
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Zheng J, Wong LR, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB Jr, Perlman S. Nature. 2020 Nov 9. doi: 10.1038/s41586-020-2943-z. Online ahead of print.

Genomic analysis of Vascular Invasion in Hepatocellular Carcinoma (HCC) Reveals Molecular Drivers and Predictive Biomarkers. Krishnan MS, Rajan Kd A, Park J, Arjunan V, Garcia Marques FJ, Bermudez A, Girvan OA, Hoang NS, Yin J, Nguyen MH, Kothary N, Pitteri S, Felsher DW, Dhanasekaran R. Hepatology. 2020 Nov 3. doi: 10.1002/hep.31614. Online ahead of print.


Week of November 3, 2020
ROS, Klotho and mTOR in cardiorenal aging. Daneshgar N, Dai DF. Aging (Albany NY). 2020 Oct 29. doi: 10.18632/aging.10420 9. Online ahead of print. No abstract available.

Multivariable Analysis of 169 Cases of Advanced Cutaneous Melanoma to Evaluate Antibiotic Exposure as Predictor of Survival to Anti-PD-1 Based Immunotherapies. Swami U, Chennamadhavuni A, Borcherding N, Bossler AD, Mott SL, Garje R, Zakharia Y, Milhem M. Antibiotics (Basel). 2020 Oct 27;9(11):E740. doi: 10.3390/antibiotics9110740.

Assessment of room quality of manual cleaning and turnaround times with and without ultraviolet light at an academic medical center. Abosi OJ, Kobayashi T, Holley S, Kukla ME, Dains A, Izakovic T, Jenn KE, Meacham H, Rogers GH, Garringer J, Millard W, Diekema DJ, Edmond MB, Wellington M, Salinas JL. Infect Control Hosp Epidemiol. 2020 Oct 29:1-2. doi: 10.1017/ice.2020.1246. Online ahead of print. No abstract available.

Endocannabinoid Receptor-1 and Sympathetic Nervous System Mediate the Beneficial Metabolic Effects of Gastric Bypass. Ye Y, Abu El Haija M, Morgan DA, Guo D, Song Y, Frank A, Tian L, Riedl RA, Burnett CML, Gao Z, Zhu Z, Shahi SK, Zarei K, Couvelard A, Poté N, Ribeiro-Parenti L, Bado A, Noureddine L, Bellizzi A, Kievit P, Mangalam AK, Zingman LV, Le Gall M, Grobe JL, Kaplan LM, Clegg D, Rahmouni K, Mokadem M. Cell Rep. 2020 Oct 27;33(4):108270. doi: 10.1016/j.celrep.2020.108270.


Week of October 27, 2020
COVID-19 Serial Testing among Hospitalized Patients in a Midwest Tertiary Medical Center, July-September 2020. Kobayashi T, Trannel A, Holley SA, Alsuhaibani M, Abosi OJ, Jenn KE, Meacham H, Sheeler LL, Etienne W, Dains A, Casado F, Kukla ME, Ward E, Ford B, Edmond MB, Wellington M, Diekema DJ, Salinas JL. Clin Infect Dis. 2020 Oct 26:ciaa1630. doi: 10.1093/cid/ciaa1630. Online ahead of print.

How current assay approval policies are leading to unintended imprecision medicine. Salgado R, Bellizzi AM, Rimm D, Bartlett JMS, Nielsen T, Holger M, Laenkholm AV, Quinn C, Cserni G, Cunha IW, Alvarado-Cabrero I, Cree I. Lancet Oncol. 2020 Oct 21:S1470-2045(20)30592-1. doi: 10.1016/S1470-2045(20)30592-1. Online ahead of print. No abstract available.

Solitary adult orbital myofibroma: Report of a case and review of the literature. Morrow NC, Tanas MR, Syed NA, Rajan Kd A. Am J Ophthalmol Case Rep. 2020 Oct 9;20:100955. doi: 10.1016/j.ajoc.2020.100955. eCollection 2020 Dec.

Glutaminase inhibitors induce thiol-mediated oxidative stress and radio-sensitization in treatment resistant cervical cancers. Rashmi R, Jayachandran K, Zhang J, Menon V, Muhammad N, Zahner M, Ruiz F, Zhang S, Cho K, Wang Y, Huang X, Huang Y, McCormick ML, Rogers BE, Spitz DR, Patti GJ, Schwarz JK. Mol Cancer Ther. 2020 Oct 21:molcanther.0271.2020. doi: 10.1158/1535-7163.MCT-20-0271. Online ahead of print.

Non-viral gene delivery embedded in biomimetically mineralized matrices for bone tissue engineering. Acri T, Laird NZ, Jaidev LR, Meyerholz DK, Salem AK, Shin K. Tissue Eng Part A. 2020 Oct 21. doi: 10.1089/ten.TEA.2020.0206. Online ahead of print.

Pharmacological ascorbate inhibits pancreatic cancer metastases via a peroxide-mediated mechanism. O'Leary BR, Alexander MS, Du J, Moose DL, Henry MD, Cullen JJ. Sci Rep. 2020 Oct 19;10(1):17649. doi: 10.1038/s41598-020-74806-2.


Week of October 20, 2020
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways. Wen W, Wang Y, Li H, Xu H, Xu M, Frank JA, Ma M, Luo J. Front Mol Neurosci. 2020 Sep 24;13:560020. doi: 10.3389/fnmol.2020.560020. eCollection 2020.

Locally invasive, castrate-resistant prostate cancer in a Pten/Trp53 double knockout mouse model of prostate cancer monitored with non-invasive bioluminescent imaging. Yong C, Moose DL, Bannick N, Gutierrez WR, Vanneste M, Svensson R, Breheny P, Brown JA, Dodd RD, Cohen MB, Henry MD. PLoS One. 2020 Sep 28;15(9):e0232807. doi: 10.1371/journal.pone.0232807. eCollection 2020.PLoS One. 2020.

Update on the activity of delafloxacin on acute bacterial skin and skin structure infection isolates from European hospitals (2014-2019). Shortridge D, Pfaller MA, Streit JM, Flamm RK. J Glob Antimicrob Resist. 2020 Oct 14:S2213-7165(20)30255-1. doi: 10.1016/j.jgar.2020.09.027. Online ahead of print.

In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy. Cheng Y, Lemke-Miltner CD, Wongpattaraworakul W, Wang Z, Chan CHF, Salem AK, Weiner GJ, Simons AL. J Immunother Cancer. 2020 Oct;8(2):e000940. doi: 10.1136/jitc-2020-000940.

Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case. Hodgson CK, Bayon R, Jensen CS, Robinson RA, Rajan K D A. Head Neck Pathol. 2020 Oct 13. doi: 10.1007/s12105-020-01233-0. Online ahead of print.


Week of October 13, 2020
Editorial: The Role of the Gut Microbiota in Health and Inflammatory Diseases. Mangalam AK, Ochoa-Repáraz J. Front Immunol. 2020 Sep 17;11:565305. doi: 10.3389/fimmu.2020.565305. eCollection 2020.

Double-homozygosity for Factor V Leiden and Prothrombin c.*97G > A Mutation in a Young Female with Recurrent Fetal Losses and no Venous Thromboembolism. Abukhiran I, Jasser J, Bhagavathi S. Human Pathology: Case Reports, 2020-11-01, Volume 22.

Insertion site inflammation was associated with central-line-associated bloodstream infections at a tertiary-care center, 2015-2018. Kobayashi T, Clore GS, Kukla ME, Alzunitan M, Kritzman J, Abosi O, Puig-Asensio M, Marra AR, Diekema DJ, Edmond MB, Salinas JL. Infect Control Hosp Epidemiol. 2020 Oct 9:1-3. doi: 10.1017/ice.2020.445. Online ahead of print.

Inducing Experimental Polymicrobial Sepsis by Cecal Ligation and Puncture. Sjaastad FV, Jensen IJ, Berton RR, Badovinac VP, Griffith TS. Curr Protoc Immunol. 2020 Dec;131(1):e110. doi: 10.1002/cpim.110.

Exposure to Static Magnetic and Electric Fields Treats Type 2 Diabetes. Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO Jr, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Cell Metab. 2020 Oct 6;32(4):561-574.e7. doi: 10.1016/j.cmet.2020.09.012.

Lack of airway submucosal glands impairs respiratory host defenses. Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, Stroik MR, Gansemer ND, Hippee CE, Zarei K, Goeken JA, Businga TR, Hoffman EA, Meyerholz DK, Prather RS, Stoltz DA, Welsh MJ. Elife. 2020 Oct 7;9:e59653. doi: 10.7554/eLife.59653.

Successful termination of an outbreak of Mycobacterium chimaera infections associated with contaminated heater-cooler devices. Marra AR, Diekema DJ, Edmond MB. Infect Control Hosp Epidemiol. 2020 Oct 6:1-3. doi: 10.1017/ice.2020.468. Online ahead of print.


Week of September 29, 2020
Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report. Yamada M, Rastogi P, Ince D, Thayyil A, Adela Mansilla M, Smith RJH, Kuppachi S, Thomas CP. Transplant Proc. 2020 Aug 20:S0041-1345(20)32679-8. doi: 10.1016/j.transproceed.2020.08.012. Online ahead of print.

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract. Ortiz ME, Thurman A, Pezzulo AA, Leidinger MR, Klesney-Tait JA, Karp PH, Tan P, Wohlford-Lenane C, McCray PB Jr, Meyerholz DK. EBioMedicine. 2020 Sep 21;60:102976. doi: 10.1016/j.ebiom.2020.102976. Online ahead of print.

Presurgical detection of brain invasion status in meningiomas based on first-order histogram based texture analysis of contrast enhanced imaging. Kandemirli SG, Chopra S, Priya S, Ward C, Locke T, Soni N, Srivastava S, Jones K, Bathla G. Clin Neurol Neurosurg. 2020 Sep 6;198:106205. doi: 10.1016/j.clineuro.2020.106205. Online ahead of print.


Week of September 22, 2020
Data on length of parathyroidectomy surgery and intraoperative parathyroid hormone (PTH) assay turnaround times following a switch in the location for intraoperative PTH testing from near point-of-care to central laboratory. Jacob D, Merrill AE, Voss DR, Bebber T, Davis SR, Kulhavy J, Krasowski MD. Data Brief. 2020 Sep 1;32:106252. doi: 10.1016/j.dib.2020.106252. eCollection 2020 Oct.

Survival of the resilient: Mechano-adaptation of circulating tumor cells to fluid shear stress. Moose DL, Henry MD. Mol Cell Oncol. 2020 May 21;7(4):1766338. doi: 10.1080/23723556.2020.1766338. eCollection 2020.

Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection. Sariol A, Mackin S, Allred MG, Ma C, Zhou Y, Zhang Q, Zou X, Abrahante JE, Meyerholz DK, Perlman S. Proc Natl Acad Sci U S A. 2020 Sep 14:202007814. doi: 10.1073/pnas.2007814117. Online ahead of print.


Week of September 15, 2020
Evaluation of switch from satellite laboratory to central laboratory for testing of intraoperative parathyroid hormone. Jacob D, Lal G, Voss DR, Bebber T, Davis SR, Kulhavy J, Sugg SL, Merrill AE, Krasowski MD. Pract Lab Med. 2020 Aug 20;22:e00176. doi: 10.1016/j.plabm.2020.e00176. eCollection 2020 Nov.

Impact of Infectious Disease Consultation in Patients With Candidemia: A Retrospective Study, Systematic Literature Review, and Meta-analysis. Kobayashi T, Marra AR, Schweizer ML, Ten Eyck P, Wu C, Alzunitan M, Salinas JL, Siegel M, Farmakiotis D, Auwaerter PG, Healy HS, Diekema DJ. Open Forum Infect Dis. 2020 Aug 3;7(9):ofaa270. doi: 10.1093/ofid/ofaa270. eCollection 2020 Sep.

Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity. Sjaastad FV, Kucaba TA, Dileepan T, Swanson W, Dail C, Cabrera-Perez J, Murphy KA, Badovinac VP, Griffith TS. Front Immunol. 2020 Aug 12;11:1786. doi: 10.3389/fimmu.2020.01786. eCollection 2020.

Radioresistance in Glioblastoma and the Development of Radiosensitizers. Ali MY, Oliva CR, Noman ASM, Allen BG, Goswami PC, Zakharia Y, Monga V, Spitz DR, Buatti JM, Griguer CE. Cancers (Basel). 2020 Sep 3;12(9):E2511. doi: 10.3390/cancers12092511.


Week of September 8, 2020
p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In Vivo. Kurup SP, Moioffer SJ, Pewe LL, Harty JT. J Immunol. 2020 Sep 4:ji2000654. doi: 10.4049/jimmunol.2000654. Online ahead of print.

Transcriptomic and Proteomic Analysis of Steatohepatitic Hepatocellular Carcinoma Reveals Novel Distinct Biologic Features. Van Treeck BJ, Mounajjed T, Moreira RK, Orujov M, Allende DS, Bellizzi AM, Lagana SM, Davila JI, Jessen E, Graham RP. Am J Clin Pathol. 2020 Sep 4:aqaa114. doi: 10.1093/ajcp/aqaa114. Online ahead of print.

Congenital intrathoracic accessory spleen is a very rare trick of nature: a case report. Suraju MO, Peyton N, Mooers B, Jensen C, Shilyansky J. J Cardiothorac Surg. 2020 Aug 31;15(1):232. doi: 10.1186/s13019-020-01270-4.


Week of September 1, 2020
Negative pressure face shield for flexible laryngoscopy in the COVID-19 era. Hoffman HT, Miller RM, Walsh JE, Stegall HR, Diekema DJ. Laryngoscope Investig Otolaryngol. 2020 Jul 29;5(4):718-726. doi: 10.1002/lio2.437. eCollection 2020 Aug.

Microvascular Decompression Versus Stereotactic Radiosurgery for Trigeminal Neuralgia: A single institution experience. Li L, Seaman SC, Bathla G, Smith MC, Dundar B, Noeller J, Hitchon PT. World Neurosurg. 2020 Jul 31;S1878-8750(20)31683-1. doi: 10.1016/j.wneu.2020.07.161. Online ahead of print.

Reduction in abdominal hysterectomy surgical site infection rates after the addition of anaerobic antimicrobial prophylaxis. Kobayashi T, Jenn KE, Bowdler N, Malloy R, Holley S, Izakovic T, Kukla ME, Abosi O, Dains A, Meacham H, Diekema DJ, Edmond MB, Salinas JL. Infect Control Hosp Epidemiol. 2020 Aug 28:1-2. doi: 10.1017/ice.2020.386. Online ahead of print.

Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells. Sinha S, Renavikar PS, Crawford MP, Steward-Tharp SM, Brate A, Tsalikian E, Tansey M, Shivapour ET, Cho T, Kamholz J, Karandikar NJ. PLoS One. 2020 Aug 27;15(8):e0238070. doi: 10.1371/journal.pone.0238070. eCollection 2020.

Spontaneous remission of genetic, apparent primary, FSGS presenting with nephrotic syndrome challenges traditional notions of primary FSGS. Oo SZMWH, Freese ME, Holanda DG, Thomas CP. J Nephrol. 2020 Aug 27. doi: 10.1007/s40620-020-00837-7. Online ahead of print.


Week of August 25, 2020
Cobblestone Malformation in LAMA2 Congenital Muscular Dystrophy (MDC1A). Jayakody H, Zarei S, Nguyen H, Dalton J, Chen K, Hudgins L, Day J, Withrow K, Pandya A, Teasley J, Dobyns WB, Mathews KD, Moore SA. J Neuropathol Exp Neurol. 2020 Sep 1;79(9):998-1010. doi: 10.1093/jnen/nlaa062.

Lymph protects metastasizing melanoma cells from ferroptosis. Ubellacker JM, Tasdogan A, Ramesh V, Shen B, Mitchell EC, Martin-Sandoval MS, Gu Z, McCormick ML, Durham AB, Spitz DR, Zhao Z, Mathews TP, Morrison SJ. Nature. 2020 Aug 19. doi: 10.1038/s41586-020-2623-z. Online ahead of print.

Neoadjuvant Radiotherapy-Related Wound Morbidity in Soft Tissue Sarcoma: Perspectives for Radioprotective Agents. Callaghan CM, Hasibuzzaman MM, Rodman SN, Goetz JE, Mapuskar KA, Petronek MS, Steinbach EJ, Miller BJ, Pulliam CF, Coleman MC, Monga VV, Milhem MM, Spitz DR, Allen BG. Cancers (Basel). 2020 Aug 12;12(8):E2258. doi: 10.3390/cancers12082258.

MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC. Dhanasekaran R, Park J, Yevtodiyenko A, Bellovin DI, Adam SJ, Kd AR, Gabay M, Fernando H, Arzeno J, Arjunan V, Gryanzov S, Felsher DW. Mol Ther Nucleic Acids. 2020 Jul 10;21:850-859. doi: 10.1016/j.omtn.2020.07.008. Online ahead of print.


Week of August 18, 2020
Exploration of PCORnet Data Resources for Assessing Use of Molecular-Guided Cancer Treatment. Carnahan RM, Waitman LR, Charlton ME, Schroeder MC, Bossler AD, Campbell WS, Campbell JR, McDowell BD, Smith NC, Gryzlak BM, Chrischilles EA. JCO Clin Cancer Inform. 2020 Aug;4:724-735. doi: 10.1200/CCI.19.00142.

Artificial Intelligence in Pathology: A Simple and Practical Guide. Yao K, Singh A, Sridhar K, Blau JL, Ohgami RS. Adv Anat Pathol. 2020 Aug 12. doi: 10.1097/PAP.0000000000000277. Online ahead of print.

Administrative coding methods impact surgical site infection rates. Alsuhaibani MA, Alzunitan MA, Jenn KE, Edmond MB, Dains AM, Holley SA, Kukla ME, Abosi OJ, Meacham HM, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2020 Aug 10:1-3. doi: 10.1017/ice.2020.340. Online ahead of print.

Loss of progesterone receptor through epigenetic regulation is associated with poor prognosis in solid tumors. Li Y, Huang C, Kavlashvili T, Fronk A, Zhang Y, Wei Y, Dai D, Devor EJ, Meng X, Thiel KW, Leslie KK, Yang S. Am J Cancer Res. 2020 Jun 1;10(6):1827-1843.


Week of August 11, 2020
Current Insights in the Development of Efficacious Vaccines Against RSV. Soto JA, Stephens LM, Waldstein KA, Canedo-Marroquín G, Varga SM, Kalergis AM. Front Immunol. 2020 Jul 17;11:1507. doi: 10.3389/fimmu.2020.01507. eCollection 2020.

Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine. Lopez CE, Legge KL. Vaccines (Basel). 2020 Aug 3;8(3):E434. doi: 10.3390/vaccines8030434.

Congenital myasthenic syndrome caused by a frameshift insertion mutation in GFPT1. Szelinger S, Krate J, Ramsey K, Strom SP, Shieh PB, Lee H, Belnap N, Balak C, Siniard AL, Russell M, Richholt R, Both M, Claasen AM, Schrauwen I, Nelson SF, Huentelman MJ, Craig DW, Yang SP, Moore SA, Sivakumar K, Narayanan V, Rangasamy S; UCLA Clinical Genomics Center. Neurol Genet. 2020 Jun 30;6(4):e468. doi: 10.1212/NXG.0000000000000468. eCollection 2020 Aug.

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. Sci Transl Med. 2020 Aug 3:eabc5332. doi: 10.1126/scitranslmed.abc5332. Online ahead of print.


Week of August 4, 2020
Corrigendum to "Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research" [Free Radic. Biol. Med. 113 (2017) 311-322]. Place TL, Domann FE, Case AJ. Free Radic Biol Med. 2020 Jul 28:S0891-5849(20)31152-7. doi: 10.1016/j.freeradbiomed.2020.07.016. Online ahead of print.

CD4 T Cell Responses and the Sepsis-Induced Immunoparalysis State. Martin MD, Badovinac VP, Griffith TS. Front Immunol. 2020 Jul 7;11:1364. doi: 10.3389/fimmu.2020.01364. eCollection 2020.

Pdgfrα-Cre mediated knockout of the aryl hydrocarbon receptor protects mice from high-fat diet induced obesity and hepatic steatosis. Gourronc FA, Markan KR, Kulhankova K, Zhu Z, Sheehy R, Quelle DE, Zingman LV, Kurago ZB, Ankrum JA, Klingelhutz AJ. PLoS One. 2020 Jul 30;15(7):e0236741. doi: 10.1371/journal.pone.0236741. eCollection 2020.

Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Lab Invest. 2020 Jul 27. doi: 10.1038/s41374-020-0474-8. Online ahead of print.

CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression. Crawford MP, Sinha S, Renavikar PS, Borcherding N, Karandikar NJ. Proc Natl Acad Sci U S A. 2020 Jul 27:202005010. doi: 10.1073/pnas.2005010117. Online ahead of print.


Week of July 28, 2020
Head-to-Head Comparison of Two SARS-CoV-2 Serology Assays. Merrill AE, Jackson JB, Ehlers A, Voss D, Krasowski MD. J Appl Lab Med. 2020 Jul 27:jfaa125. doi: 10.1093/jalm/jfaa125. Online ahead of print.

Epithelial-mesenchymal transition polarization in ovarian carcinomas from patients with high social isolation. Lutgendorf SK, Penedo F, Goodheart MJ, Dahmoush L, Arevalo JMG, Thaker PH, Slavich GM, Sood AK, Cole SW. Cancer. 2020 Jul 21. doi: 10.1002/cncr.33060. Online ahead of print.