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Recent Publications

Week of September 19, 2023
Targeting the Angiotensin Pathway in the Treatment of Cutaneous Fibrosis: A Systematic Review. Greif T, Alsawas M, Reid AT, Liu V, Prokop L, Murad MH, Powers JG. JID Innovations 2023; 100231. doi: 10.1016/j.xjidi.2023.100231.

Week of September 5, 2023
Risk Factors for Fibrous Ingrowth in Eyes Requiring Primary Keratoplasty. Ramirez DA, Walling AL, Fortenbach CR, Witsberger E, Frey K, Jiang L, Syed NA, Zimmerman MB, Greiner MA, Sales CS. Cornea. 2023 Aug 25. doi: 10.1097/ICO.0000000000003326. Online ahead of print.

Low Host Immune Pressure May be Associated with the Development of Hepatocellular Carcinoma: A Longitudinal Analysis of Complete Genomes of the HBV 1762T, 1764A Mutant. Jiang Z-J, Chen Q-Y, Jia H-H, Wang X-Y, Zhang L-J, Huang X-Q, Harrison TJ, Jackson JB, Wu L, Fang Z-L. Front Oncol 2023; 13:1214423. doi: 10.3389/fonc.2023.1214423.

Week of August 29, 2023
A Reassessment of the Impact and Significance of Social Media to Pathology. Chen SJT, Samuelson MI, Kd AR. Arch Pathol Lab Med. 2023 Aug 28. doi: 10.5858/arpa.2022-0463-RA. Online ahead of print.

Predictors of mortality in Ugandan children with TB, 2016–2021. Becker GL, Amuge P, Ssebunya R, Motevalli M, Adaku A, Juma M, Wobudeya E, Elyanu P, Jackson JB, Kekitiinwa A, Blount RJ. The International Journal of Tuberculosis and Lung Disease, Volume 27, Number 9, 1 September 2023, pp. 668-674(7). doi: 10.5588/ijtld.22.0622.

Week of August 15, 2023
Francis S. Morrison MD-Tribute to an apheresis leader. Linz W, Thigpen JT, Strauss RG. J Clin Apher. 2023 Aug 10. doi: 10.1002/jca.22075. Online ahead of print.

Week of August 8, 2023
Plaque-Like Lesions in the Gastrointestinal Tract. Durham K, Zhang X, Xiong Y, Reddy A, Polyak S. ACG Case Rep J. 2023 Aug 2;10(8):e01115. doi: 10.14309/crj.0000000000001115. eCollection 2023 Aug.

Use of subgroup-specific hematopoietic stem cell collection efficiencies to improve truncation calculations for large-volume leukapheresis procedures. Rogers KJ, Mott SL, Parsons MG, Schlueter AJ. J Clin Apher. 2023 Aug 1. doi: 10.1002/jca.22077. Online ahead of print.

Diagnosis, Treatment, and Prevention of Pediatric Lyme Disease. Mooberry ME, Becker GL, Voss NA, Jackson JB. Microbiology Infectious Diseases 2023;7:1-5.

Week of August 1, 2023
Diagnostic performance of fluorescence microscopy with a tetramethylrhodamine isothiocyanate filter in identifying renal amyloidosis. Pinedo Pichilingue A, Thayyil A, Dai DF, Rastogi P. Histopathology. 2023 Jul 28. doi: 10.1111/his.15014. Online ahead of print.

Week of July 25, 2023
Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence. Li P, Xue B, Schnicker NJ, Wong LR, Meyerholz DK, Perlman S. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2305674120. doi: 10.1073/pnas.2305674120. Epub 2023 Jul 24.

Asian Americans in STEM are not a monolith. Vue Z, Vang C, Vue N, Kamalumpundi V, Barongan T, Shao B, Huang S, Vang L, Vue M, Vang N, Shao J, Coombes C, Katti P, Liu K, Yoshimura K, Biete M, Dai DF, Phillips MA, Behringer RR. Cell. 2023 Jul 20;186(15):3138-3142. doi: 10.1016/j.cell.2023.06.017.

p53 as Exemplar Next-generation Immunohistochemical Marker: A Molecularly Informed, Pattern-based Approach, Methodological Considerations, and Pan-cancer Diagnostic Applications. Bellizzi AM. Appl Immunohistochem Mol Morphol. 2023 Jul 21. doi: 10.1097/PAI.0000000000001144. Online ahead of print.

Histology and clinical correlations in autoimmune hepatitis, primary biliary cholangitis, and autoimmune hepatitis-primary biliary cholangitis overlap syndrome. Liang Y, Khandakar B, Hao Y, Xiong Y, Liu BL, Zhang X. Ann Diagn Pathol. 2023 Jul 12:152178. doi: 10.1016/j.anndiagpath.2023.152178. Online ahead of print.

Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer. Jiang Z, Ju Y, Ali A, Chung PED, Skowron P, Wang DY, Shrestha M, Li H, Liu JC, Vorobieva I, Ghanbari-Azarnier R, Mwewa E, Koritzinsky M, Ben-David Y, Woodgett JR, Perou CM, Dupuy A, Bader GD, Egan SE, Taylor MD, Zacksenhaus E. Nat Commun. 2023 Jul 18;14(1):4313. doi: 10.1038/s41467-023-39935-y.

Immunomodulatory Effects of Subacute Inhalation Exposure to Copper Oxide Nanoparticles in House Dust Mite-Induced Asthma. Areecheewakul S, Adamcakova-Dodd A, Zacharias ZR, Jing X, Meyerholz DK, Legge KL, Houtman JCD, O'Shaughnessy PT, Thorne PS, Salem AK. ACS Nano. 2023 Jul 18. doi: 10.1021/acsnano.3c01668. Online ahead of print.

Asymptomatic testing of hospital admissions for SARS-CoV-2: Is it OK to stop? Brust K, Kobayashi T, Diekema DJ. Clin Infect Dis. 2023 Jul 18:ciad423. doi: 10.1093/cid/ciad423. Online ahead of print.

The National Association of Medical Examiners Position Paper: Second Autopsies. Aiken SS, Nashelsky M. Am J Forensic Med Pathol. 2023 Jul 8. doi: 10.1097/PAF.0000000000000853. Online ahead of print.

Week of July 18, 2023
Gut microbiota short-chain fatty acids and their impact on the host thyroid function and diseases. Mendoza-León MJ, Mangalam AK, Regaldiz A, González-Madrid E, Rangel-Ramírez MA, Álvarez-Mardonez O, Vallejos OP, Méndez C, Bueno SM, Melo-González F, Duarte Y, Opazo MC, Kalergis AM, Riedel CA. Front Endocrinol (Lausanne). 2023 Jun 30;14:1192216. doi: 10.3389/fendo.2023.1192216. eCollection 2023.

Susceptibility patterns of amphotericin B, itraconazole, posaconazole, voriconazole and caspofungin for isolates causing invasive mould infections from the SENTRY Antifungal Surveillance Program (2018-2021) and application of single-site epidemiological cutoff values to evaluate amphotericin B activity. Pfaller MA, Carvalhaes CG, Castanheira M. Mycoses. 2023 Jul 11. doi: 10.1111/myc.13620. Online ahead of print.

Week of July 11, 2023
CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression. Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, Leidinger M, Breheny P, Chimenti MS, Sieren JC, Monga V, Tanas MR, Meyerholz DK, Darbro BW, Dodd RD, Quelle DE. Clin Cancer Res. 2023 Jul 6:CCR-23-0749. doi: 10.1158/1078-0432.CCR-23-0749. Online ahead of print.

Week of July 4, 2023
Recurrent TRAK1::RAF1 Fusions in pediatric low-grade gliomas. Benhamida JK, Harmsen HJ, Ma D, William CM, Li BK, Villafania L, Sukhadia P, Mullaney KA, Dewan MC, Vakiani E, Karajannis MA, Snuderl M, Zagzag D, Ladanyi M, Rosenblum MK, Bale TA. Brain Pathol. 2023 Jul 3:e13185. doi: 10.1111/bpa.13185. Online ahead of print.

Evaluating the iron chelator function of sirtinol in non-small cell lung cancer. Petronek MS, Bayanbold K, Amegble K, Tomanek-Chalkley AM, Allen BG, Spitz DR, Bailey CK. Front Oncol. 2023 Jun 15;13:1185715. doi: 10.3389/fonc.2023.1185715. eCollection 2023.

MYC overexpression in inflammatory bowel disease-associated conventional dysplasia and association of subsequent low-grade dysplasia in follow-up biopsies. Liang Y, Hao Y, Xiong Y, Zhong M, Jain D. Pathol Res Pract. 2023 Jun 21;248:154642. doi: 10.1016/j.prp.2023.154642. Online ahead of print.

CD40 Signaling in Mice Elicits a Broad Antiviral Response Early during Acute Infection with RNA Viruses. Rogers KJ, Richards PT, Zacharias ZR, Stunz LL, Vijay R, Butler NS, Legge KL, Bishop GA, Maury W. Viruses. 2023 Jun 12;15(6):1353. doi: 10.3390/v15061353.

Large Perianal Tailgut Cyst with Invasive Squamous Cell Carcinoma and Low-Grade Mucinous Neoplasm. Choi A, Findlay S, Xiong Y. J Gastrointest Surg. 2023 Jun 27. doi: 10.1007/s11605-023-05763-0. Online ahead of print.

In Vitro Activity of Isavuconazole and Other Mould-Active Azoles against Aspergillus fumigatus with and without CYP51 Alterations. Pfaller MA, Carvalhaes CG, Deshpande LM, Rhomberg PR, Castanheira M. J Fungi (Basel). 2023 May 25;9(6):608. doi: 10.3390/jof9060608.

Week of June 27, 2023
Sublethal whole-body irradiation induces permanent loss and dysfunction in pathogen-specific circulating memory CD8 T cell populations. Heidarian M, Jensen IJ, Kannan SK, Pewe LL, Hassert M, Park S, Xue HH, Harty JT, Badovinac VP. Proc Natl Acad Sci U S A. 2023 Jul 4;120(27):e2302785120. doi: 10.1073/pnas.2302785120. Epub 2023 Jun 26.

Patterns of gender identity data within electronic health record databases can be used as a tool for identifying and estimating the prevalence of gender-expansive people. Hines NG, Greene DN, Imborek KL, Krasowski MD. JAMIA Open. 2023 Jun 24;6(2):ooad042. doi: 10.1093/jamiaopen/ooad042. eCollection 2023 Jul.

Immunohistochemical detection of MUC5AC and MUC5B mucins in ferrets. Meyerholz DK, Leidinger MR, Adam Goeken J, Businga TR, Vizuett S, Akers A, Evans I, Zhang Y, Engelhardt JF. BMC Res Notes. 2023 Jun 22;16(1):111. doi: 10.1186/s13104-023-06388-x.

Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales. Bosch DE, Abbasian R, Parajuli B, Peterson SB, Mougous JD. mBio. 2023 Jun 22:e0103923. doi: 10.1128/mbio.01039-23. Online ahead of print.

What Is New in Fungal Infections? Parsons MG, Diekema DJ. Mod Pathol. 2023 Jun;36(6):100187. doi: 10.1016/j.modpat.2023.100187. Epub 2023 Apr 13.

Surgical Site Infection Rates Following Mohs Micrographic Surgery by Body Site: A Systematic Review and Meta-Analysis. Chen A, Alsawas M, Tan KW, Prokop L, Murad MH, Powers JG. J Am Acad Dermatol. 2023 Jun 24:S0190-9622(23)01194-5. doi: 10.1016/j.jaad.2023.06.032.

Week of June 20, 2023
Utilization of commercial collagens for preparing well-differentiated human beta cells for confocal microscopy. Brennecke BR, Yang U, Liu S, Ilerisoy FS, Ilerisoy BN, Joglekar A, Kim LB, Peachee SJ, Richtsmeier SL, Stephens SB, Sander EA, Strack S, Moninger TO, Ankrum JA, Imai Y. Front Endocrinol (Lausanne). 2023 May 25;14:1187216. doi: 10.3389/fendo.2023.1187216. eCollection 2023.

Week of June 13, 2023
Role of A-Kinase Anchoring Protein 1 in Retinal Ganglion Cells: Neurodegeneration and Neuroprotection. Bastola T, Perkins GA, Kim KY, Choi S, Kwon JW, Shen Z, Strack S, Ju WK. Cells. 2023 Jun 3;12(11):1539. doi: 10.3390/cells12111539.

Systematic Evaluation of Hematologic Parameters and Blood Smear Findings in Patients With SARS-CoV-2 vs Other Viral Respiratory Infections. Chopra S, Karandikar NJ, Holman CJ. Am J Clin Pathol. 2023 Jun 8:aqad061. doi: 10.1093/ajcp/aqad061. Online ahead of print.

EGFR and ERBB2 exon 20 insertion/duplication in advanced non-small cell lung cancer: genomic profiling and clinicopathologic features. Sompallae RR, Dundar B, Guseva NV, Bossler AD, Ma D. Front Oncol. 2023 May 22;13:1163485. doi: 10.3389/fonc.2023.1163485. eCollection 2023.

Comparison of platelet antibody screen, crossmatching and HLA antibody testing in patients refractory to platelet transfusions. Chapman JM, Wendt L, Knudson CM. Transfus Apher Sci. 2023 Jun;62(3):103622. doi: 10.1016/j.transci.2022.103622. Epub 2022 Dec 10.

Week of June 6, 2023
The mTOR signaling pathway in cardiac aging. Dai DF, Kang P, Bai H. J Cardiovasc Aging. 2023;3(3):24. doi: 10.20517/jca.2023.10. Epub 2023 May 4.

Nicotine and Tobacco Alkaloid Testing and Challenges: Lessons Learned From a College of American Pathologists Proficiency Testing Survey. Snozek CLH, McMillin GA, Nwosu A, Dizon A, Krasowski MD. Arch Pathol Lab Med. 2023 Jun 1;147(6):634-642. doi: 10.5858/arpa.2022-0094-CP.

Week of May 30, 2023
Mitochondrial Oxidative Stress Mediates Bradyarrhythmia in Leigh Syndrome Mitochondrial Disease Mice. Chen B, Daneshgar N, Lee HC, Song LS, Dai DF. Antioxidants (Basel). 2023 Apr 26;12(5):1001. doi: 10.3390/antiox12051001.

Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart. Marshall AG, Neikirk K, Vue Z, Beasley HK, Garza-Lopez E, Vang L, Barongan T, Evans Z, Crabtree A, Spencer E, Anudokem J Jr, Parker R, Davis J, Stephens D, Damo S, Pham TT, Gomez JA, Exil V, Dai DF, Murray SA, Entman ML, Taffet GE, Hinton AO Jr, Reddy AK. Front Cardiovasc Med. 2023 May 9;10:1064640. doi: 10.3389/fcvm.2023.1064640. eCollection 2023.

Prevalence of maternal complications and neonatal outcomes at a Midwest academic health center. Swartz SR, Kenne KA, Steffen HA, Bujimalla PV, Wendt LH, Jackson JB, Rysavy MB. Proc Obstet Gynecol. 2023;12(1): Article 5 [12 p.].

Week of May 23, 2023
Characterization of CPH:SA microparticle-based delivery of interleukin-1 alpha for cancer immunotherapy. Hasibuzzaman MM, He R, Khan IN, Sabharwal R, Salem AK, Simons-Burnett AL. Bioeng Transl Med. 2022 Dec 7;8(3):e10465. doi: 10.1002/btm2.10465. eCollection 2023 May.

Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis. Lehman PC, Cady N, Ghimire S, Shahi SK, Shrode RL, Lehmler HJ, Mangalam AK. Environ Toxicol Pharmacol. 2023 May 15;100:104149. doi: 10.1016/j.etap.2023.104149. Online ahead of print.

Essential Protein PHB2 and Its Regulatory Mechanisms in Cancer. Qi A, Lamont L, Liu E, Murray SD, Meng X, Yang S. Cells. 2023 Apr 21;12(8):1211. doi: 10.3390/cells12081211.

Multi-Institutional Study of Pathologist Reading of the Programmed Cell Death Ligand-1 Combined Positive Score Immunohistochemistry Assay for Gastric or Gastroesophageal Junction Cancer. Fernandez AI, Robbins CJ, Gaule P, Agostini-Vulaj D, Anders RA, Bellizzi AM, Chen W, Chen ZE, Gopal P, Zhao L, Lisovsky M, Liu X, Shia J, Wang H, Yang Z, McCann L, Chan YG, Weidler J, Bates M, Zhang X, Rimm DL. Mod Pathol. 2023 May;36(5):100128. doi: 10.1016/j.modpat.2023.100128. Epub 2023 Feb 13.

A novel subgenotype I3 of hepatitis B virus in Guangxi, China: a 15-year follow-up study. Jia HH, Chen QY, Jiang ZH, Wang XY, Zhang WJ, He X, Harrison TJ, Jackson JB, Wu L, Fang ZL. Virus Genes. 2023 Jun;59(3):359-369. doi: 10.1007/s11262-023-01980-6. Epub 2023 Feb 25.

Week of May 16, 2023
Quantification of capture efficiency, purity, and single-cell isolation in the recovery of circulating melanoma cells from peripheral blood by dielectrophoresis. Chen H, Osman SY, Moose DL, Vanneste M, Anderson JL, Henry MD, Anand RK. Lab Chip. 2023 Apr 26. doi: 10.1039/d2lc01113a. Online ahead of print.

Consensus recommendations for management of high grade neuroendocrine tumors. Eads JR, Halfdanarson TR, Asmis T, Bellizzi AM, Bergsland EK, Dasari A, El-Haddad G, Frumovittz M, Meyer J, Mittra E, Myrehaug S, Nakakura E, Raj N, Soares HP, Untch B, Vijayvergia N, Chan JA. Endocr Relat Cancer. 2023 May 1:ERC-22-0206. doi: 10.1530/ERC-22-0206. Online ahead of print.

Development and validation of a standardized blood culture contamination definition and metric dashboard for a large health care system. Hancock JA, Campbell S, Jones MM, Wang-Rodriguez J; VHA Microbiology SME Workgroup; Klutts JS. Am J Clin Pathol. 2023 May 11:aqad044. doi: 10.1093/ajcp/aqad044. Online ahead of print.

Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate. Petronek MS, Teferi N, Caster JM, Stolwijk JM, Zaher A, Buatti JM, Hasan D, Wafa EI, Salem AK, Gillan EG, St-Aubin JJ, Buettner GR, Spitz DR, Magnotta VA, Allen BG. Redox Biol. 2023 Jun;62:102651. doi: 10.1016/j.redox.2023.102651. Epub 2023 Mar 7.

Week of May 9, 2023
Does Antimicrobial Prophylaxis in Patients with Specific Comorbidities Reduce the Risk of Infection after Simple Cystourethroscopy? Sherwood BG, Takacs EB, Ford BA, Mott SL, Loeffler BT, Lockwood GM. Urol Pract. 2022 Sep;9(5):414-422. doi: 10.1097/UPJ.0000000000000325. Epub 2022 Sep 1.

Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization. Tolan NV, Krasowski MD, Mathias PC, Wiencek JR, Babic N, Chai PR, Chambliss AB, Choucair I, Demetriou CA, Erickson TB, Feldhammer M, French D, Hayes BD, Kang P, El-Khoury JM, Knezevic CE, Monte A, Nerenz RD, Okorodudu AO, Roper SM, Saitman A, Thiriveedhi V, Uljon SN, Vest A, Woodworth A, Yu M, Melanson SEF. Clin Toxicol (Phila). 2023 Apr;61(4):248-259. doi: 10.1080/15563650.2023.2177552.

Commotio Cordis and One Medicine. Meyerholz DK. Vet Pathol. 2023 May;60(3):291-293. doi: 10.1177/03009858231162223. Epub 2023 Mar 23.

DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation. Teghanemt A, Misel-Wuchter K, Heath J, Thurman A, Pulipati P, Dixit G, Geesala R, Meyerholz DK, Maretzky T, Pezzulo A, Issuree PD. EMBO Rep. 2023 May 4;24(5):e55543. doi: 10.15252/embr.202255543. Epub 2023 Mar 7.

Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy. Allen BD, Alaghband Y, Kramár EA, Ru N, Petit B, Grilj V, Petronek MS, Pulliam CF, Kim RY, Doan NL, Baulch JE, Wood MA, Bailat C, Spitz DR, Vozenin MC, Limoli CL. Neuro Oncol. 2023 May 4;25(5):927-939. doi: 10.1093/neuonc/noac248.

Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat. Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Mol Cell Biochem. 2023 Jun;478(6):1231-1244. doi: 10.1007/s11010-022-04589-9. Epub 2022 Oct 25.

Week of May 2, 2023
IL-17 cytokines preferentially act on naïve CD4+ T cells with the IL-17AF heterodimer inducing the greatest functional changes. Crawford MP, Borcherding N, Karandikar NJ. PLoS One. 2023 Apr 28;18(4):e0285166. doi: 10.1371/journal.pone.0285166. eCollection 2023.

Evaluating the utility of a two-assay serological algorithm for hepatitis C screening in a low prevalence population. Rogers KJ, Halvorson TS, Krasowski MD, Merrill AE. J Clin Lab Anal. 2023 Apr 27:e24887. doi: 10.1002/jcla.24887. Online ahead of print.

Week of April 25, 2023
Pandemic Demand for SARS-CoV-2 Testing Led to Critical Supply and Workforce Shortages in U.S. Clinical and Public Health Laboratories. Cornish NE, Bachmann LH, Diekema DJ, McDonald LC, McNult P, Stevens-Garcia J, Raphael BH, Miller MB. J Clin Microbiol. 2023 Apr 18:e0318920. doi: 10.1128/jcm.03189-20. Online ahead of print.

CD4 T Cell-Dependent and -Independent Roles for IFN-γ in Blood-Stage Malaria. Drewry LL, Pewe LL, Hancox LS, Van de Wall S, Harty JT. J Immunol. 2023 May 1;210(9):1305-1313. doi: 10.4049/jimmunol.2200899.

Week of April 18, 2023
What's New in Fungal Infections? Parsons MG, Diekema DJ. Mod Pathol. 2023 Apr 12:100187. doi: 10.1016/j.modpat.2023.100187. Online ahead of print.

Week of April 11, 2023
The Detrimental Impact of End-Stage Kidney Disease Is Not Reflected in Autopsy Reports. Lerner GB, Reynolds MA, Setty S, Deeb R, Rastogi P, Moeckel G, Sanchez H, Henriksen KJ, Chang A. Arch Pathol Lab Med. 2023 Apr 5. doi: 10.5858/arpa.2022-0338-OA. Online ahead of print.

Memory CD8+ T cell-mediated protection against liver-stage malaria. Hassert M, Arumugam S, Harty JT. Immunol Rev. 2023 Apr 4. doi: 10.1111/imr.13202. Online ahead of print.

Week of April 4, 2023
A De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy. Marcelot A, Rodriguez-Tirado F, Cuniasse P, Joiner ML, Miron S, Soshnev AA, Fang M, Pufall MA, Mathews KD, Moore SA, Zinn-Justin S, Geyer PK. Cells. 2023 Mar 9;12(6):847. doi: 10.3390/cells12060847.

Primary spontaneous listerial peritonitis. Tholany J, Samra H, Kobayashi T, Prasidthrathsint K. IDCases. 2023 Mar 16;32:e01748. doi: 10.1016/j.idcr.2023.e01748. eCollection 2023.

Week of March 28, 2023
The Low Prevalence and High Cost of Routine Antiphospholipid Antibody Testing in Patients with Recurrent Pregnancy Loss. Cafun RG, Merrill A, Bhagavathi SM, Summers KM, Bettendorf BA, Van Voorhis BJ. Fertil Steril. 2023 Mar 25:S0015-0282(23)00235-2. doi: 10.1016/j.fertnstert.2023.03.026. Online ahead of print.

Utilizing digital pathology and immunohistochemistry of p53 as an adjunct to molecular testing in myeloid disorders. Rogers KJ, Abukhiran IM, Syrbu S, Tomasson M, Bates M, Dhakal P, Bhagavathi S. Acad Pathol. 2023 Feb 1;10(1):100064. doi: 10.1016/j.acpath.2022.100064. eCollection 2023 Jan-Mar.

A ciprofloxacin derivative with four mechanisms of action overcomes paclitaxel resistance in p53-mutant and MDR1 gene-expressing type II human endometrial cancer. Alhaj-Suliman SO, Naguib YW, Wafa EI, Saha S, Ebeid K, Meng X, Mohammed HH, Abuo-Rahma GEA, Yang S, Salem AK. Biomaterials. 2023 Mar 17;296:122093. doi: 10.1016/j.biomaterials.2023.122093. Online ahead of print.

Commotio Cordis and One Medicine. Meyerholz DK. Vet Pathol. 2023 Mar 23:3009858231162223. doi: 10.1177/03009858231162223. Online ahead of print.

Week of March 21, 2023
Effect of a Fructose-Rich Diet on Gut Microbiota and Immunomodulation: Potential Factors for Multiple Sclerosis. Peterson SR, Ali S, Shrode RL, Mangalam AK. Immunohorizons. 2023 Mar 1;7(3):213-227. doi: 10.4049/immunohorizons.2300008.

Characteristics of Renal Intravascular Large B-cell Lymphoma. Rastogi P, Alrwashdeh A, Caza T, Lin M, Obeidat M, Giannini G, Larsen C, Dai DF. Kidney Int Rep. 2022 Dec 13;8(3):575-583. doi: 10.1016/j.ekir.2022.12.001. eCollection 2023 Mar.

A dataset examining the impact of direct electronic medical record interfacing on the accuracy of point-of-care urinalysis results. Rogers KJ, Krasowski MD. Data Brief. 2023 Mar 1;47:109012. doi: 10.1016/j.dib.2023.109012. eCollection 2023 Apr.

Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate. Petronek MS, Teferi N, Caster JM, Stolwijk JM, Zaher A, Buatti JM, Hasan D, Wafa EI, Salem AK, Gillan EG, St-Aubin JJ, Buettner GR, Spitz DR, Magnotta VA, Allen BG. Redox Biol. 2023 Mar 7;62:102651. doi: 10.1016/j.redox.2023.102651. Online ahead of print.

Week of March 14, 2023
Cutting Edge: Influenza-Induced CD11alo Airway CD103+ Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation. van de Wall S, Crooks S, Varga SM, Badovinac VP, Harty JT. J Immunol. 2023 Mar 13:ji2200931. doi: 10.4049/jimmunol.2200931. Online ahead of print.

Decoding Postinfarction Left Ventricular Pseudoaneurysm. Nguyen EK, Suksaranjit P, Bashir MA, Firchau DJ, Gebska MA. JACC Case Rep. 2022 Nov 3;9:101533. doi: 10.1016/j.jaccas.2022.07.005. eCollection 2023 Mar 1.

Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins. Betters RK, Luhmann E, Gottschalk AC, Xu Z, Shin MR, Ptak CP, Fiock KL, Radoshevich LC, Hefti MM. eNeuro. 2023 Mar 10:ENEURO.0503-22.2023. doi: 10.1523/ENEURO.0503-22.2023. Online ahead of print.

MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint. Smith BAH, Deutzmann A, Correa KM, Delaveris CS, Dhanasekaran R, Dove CG, Sullivan DK, Wisnovsky S, Stark JC, Pluvinage JV, Swaminathan S, Riley NM, Rajan A, Majeti R, Felsher DW, Bertozzi CR. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2215376120. doi: 10.1073/pnas.2215376120. Epub 2023 Mar 10.

Elevated Intraocular Pressure in Periorbital Sweet's Syndrome. Keen JA, Fisher MD, Yu CY, Swick BL, Shriver EM. Ophthalmic Plast Reconstr Surg. 2023 Mar 9. doi: 10.1097/IOP.0000000000002373. Online ahead of print.

DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation. Teghanemt A, Misel-Wuchter K, Heath J, Thurman A, Pulipati P, Dixit G, Geesala R, Meyerholz DK, Maretzky T, Pezzulo A, Issuree PD. EMBO Rep. 2023 Mar 7:e55543. doi: 10.15252/embr.202255543. Online ahead of print.

Week of March 7, 2023
Diagnostic Stewardship to Prevent Diagnostic Error. Morgan DJ, Malani PN, Diekema DJ. JAMA. 2023 Mar 2. doi: 10.1001/jama.2023.1678. Online ahead of print.

Thioflavin S Staining and Amyloid Formation Are Unique to Mixed Tauopathies. Fiock KL, Betters RK, Hefti MM. J Histochem Cytochem. 2023 Mar 2:221554231158428. doi: 10.1369/00221554231158428. Online ahead of print.

Antibiotic Recommendations for Treatment of Canine Stromal Corneal Ulcers. Joksimovic M, Ford BA, Lazic T, Soldatovic I, Luzetsky S, Grozdanic S. Vet Sci. 2023 Jan 17;10(2):66. doi: 10.3390/vetsci10020066.

Adolescent- and adult-initiated alcohol exposure in mice differentially promotes tumorigenesis and metastasis of breast cancer. Xu M, Li H, Chen D, Wu H, Wen W, Xu H, Frank J, Chen G, Luo J. Alcohol Clin Exp Res. 2023 Feb;47(2):251-262. doi: 10.1111/acer.14986. Epub 2022 Dec 10.

Week of February 28, 2023
A novel subgenotype I3 of hepatitis B virus in Guangxi, China: a 15-year follow-up study. Jia HH, Chen QY, Jiang ZH, Wang XY, Zhang WJ, He X, Harrison TJ, Jackson JB, Wu L, Fang ZL. Virus Genes. 2023 Feb 25. doi: 10.1007/s11262-023-01980-6. Online ahead of print.

Altered MANF Expression in Pancreatic Acinar and Ductal Cells in Chronic Alcoholic Pancreatitis: A Cross-Sectional Study. Caldwell NJ, Li H, Bellizzi AM, Luo J. Biomedicines. 2023 Feb 2;11(2):434. doi: 10.3390/biomedicines11020434.

Week of February 21, 2023
DUX4 double whammy: The transcription factor that causes a rare muscular dystrophy also kills the precursors of the human nose. Inoue K, Bostan H, Browne MR, Bevis OF, Bortner CD, Moore SA, Stence AA, Martin NP, Chen SH, Burkholder AB, Li JL, Shaw ND. Sci Adv. 2023 Feb 17;9(7):eabq7744. doi: 10.1126/sciadv.abq7744. Epub 2023 Feb 17.

Translucent Papules of the Periorbital Area: Challenge. Holder K, Tan KW, Patrick AP, Stone MS. Am J Dermatopathol. 2023 Mar 1;45(3):e13-e14. doi: 10.1097/DAD.0000000000002346.

Translucent Papules of the Periorbital Area: Answer. Holder K, Tan KW, Patrick AP, Stone MS. Am J Dermatopathol. 2023 Mar 1;45(3):203-204. doi: 10.1097/DAD.0000000000002347.

Principles of diagnostic stewardship: A practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force. Fabre V, Davis A, Diekema DJ, Granwehr B, Hayden MK, Lowe CF, Pfeiffer CD, Sick-Samuels AC, Sullivan KV, Van Schooneveld TC, Morgan DJ. Infect Control Hosp Epidemiol. 2023 Feb;44(2):178-185. doi: 10.1017/ice.2023.5.

Hyperacute immune responses associate with immediate neuropathology and motor dysfunction in large vessel occlusions. Farooqui M, Ortega-Gutierrez S, Hernandez K, Torres VO, Dajles A, Zevallos CB, Quispe-Orozco D, Mendez-Ruiz A, Manzel K, Ten Eyck P, Tranel D, Karandikar NJ, Ortega SB. Ann Clin Transl Neurol. 2023 Feb;10(2):276-291. doi: 10.1002/acn3.51719. Epub 2022 Dec 28.

The neuropathologic findings in a case of progressive cavitating leukoencephalopathy due to NDUFV1 pathogenic variants. Becker N, Sharma A, Gosse M, Kubat B, Conway KS. Acta Neuropathol Commun. 2022 Sep 26;10(1):142. doi: 10.1186/s40478-022-01445-1.

Co-occurrence of VHL and SDHA Pathogenic Variants: A Case Report. Tung ML, Chandra B, Dillahunt K, Gosse MD, Sato TS, Sidhu A. Front Oncol. 2022 Jul 7;12:925582. doi: 10.3389/fonc.2022.925582.

Ileocolonic intussusception presenting as chronic diarrhea in an elderly woman. Ali A, Lee YJ, Gosse M, Meade C, Labath H, Murali AR. VideoGIE. 2022 Dec 14;8(2):89-91. doi: 10.1016/j.vgie.2022.10.008.

Congestive Hepatopathy: A Case of Fontan-Associated Liver Disease and Review of Literature. Gosse M, Bosch D. AJSP: Reviews & Reports 27(6):p 241-247, 11/12 2022. | DOI: 10.1097/PCR.0000000000000534 

Week of February 14, 2023
Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets. Heidarian M, Griffith TS, Badovinac VP. Front Immunol. 2023 Jan 23;14:1130009. doi: 10.3389/fimmu.2023.1130009. eCollection 2023.

Practice patterns for reporting digestive system neuroendocrine neoplasms: results from a large, comprehensive international survey. Karamchandani DM, Cox B, La Rosa S, Bellizzi AM, Shi C, Gonzalez RS. Histopathology. 2023 Mar;82(4):541-554. doi: 10.1111/his.14851. Epub 2023 Jan 3.

Tumor to Tumor Metastasis: A Case Report of Metastatic Angiosarcoma to an Ovarian Brenner Tumor and Review of the Literature. Dundar B, Alrwashdeh A, Dahmoush L. Int J Gynecol Pathol. 2023 Mar 1;42(2):176-181. doi: 10.1097/PGP.0000000000000854. Epub 2022 Mar 11.

Week of February 7, 2023
Activated microglia and neuroinflammation as a pathogenic mechanism in Leigh syndrome. Daneshgar N, Leidinger MR, Le S, Hefti M, Prigione A, Dai DF. Front Neurosci. 2023 Jan 18;16:1068498. doi: 10.3389/fnins.2022.1068498. eCollection 2022.

Strong Annexin A10 Expression Supports a Pancreatic Primary and Combined Annexin A10, Claudin 18, and SOX2 Expression Supports an Esophagogastric Origin in Carcinomas of Unknown Primary. Isidro RA, Abukhiran I, Dunseth CD, Gosse MD, Humble RM, Pelletier DJ, Varshney N, Bellizzi AM, Hornick JL. Am J Surg Pathol. 2022 Nov 2. doi: 10.1097/PAS.0000000000001994. Online ahead of print.

Cutaneous Metastasis of Alveolar Rhabdomyosarcoma in a Child. Nör F, Castro JP, Wongpattaraworakul W, Buatti JM, Gordon D, Powers JG, Terry W, Hellstein J, Tanas M, Stone M. Am J Dermatopathol. 2023 Jan 10. doi: 10.1097/DAD.0000000000002382. Online ahead of print.

Low-Cost, High-Pressure-Synthesized Oxygen-Entrapping Materials to Improve Treatment of Solid Tumors. Bi J, Witt E, Voltarelli VA, Feig VR, Venkatachalam V, Boyce H, McGovern M, Gutierrez WR, Rytlewski JD, Bowman KR, Rhodes AC, Cook AN, Muller BN, Smith MG, Ramos AR, Panchal H, Dodd RD, Henry MD, Mailloux A, Traverso G, Otterbein LE, Byrne JD. Adv Sci (Weinh). 2023 Feb 2:e2205995. doi: 10.1002/advs.202205995. Online ahead of print.

Metastatic Disease to a Concurrent Thyroid Neoplasm: A Case Series and Review of the Literature. Garneau M, Alyzadneh E, Lal G, Rajan Kd A. Head Neck Pathol. 2023 Jan 31. doi: 10.1007/s12105-022-01509-7. Online ahead of print.

Hyperbaric oxygen exposure alleviate metabolic side-effects of olanzapine treatment and is associated with Langerhans islet proliferation in rats. AlQudah M, Khalifeh M, Al-Azaizeh R, Masaadeh A, Al-Rusan OM, Haddad HK. Pathol Oncol Res. 2022 Dec 16;28:1610752. doi: 10.3389/pore.2022.1610752. 

Week of January 31, 2023
Concerns about pathology expertise and data quality. McInnes EF, Meyerholz DK, Arends MJ. J Pathol. 2023 Jan 30. doi: 10.1002/path.6058. Online ahead of print.

Week of January 24, 2023
Ventriculus terminalis cyst in an infant: a case report. Menezes AH, Sato Y, Dlouhy BJ, Jones KA, Moore SA. J Med Case Rep. 2023 Jan 23;17(1):22. doi: 10.1186/s13256-023-03759-7.

Human Brainstem and Cerebellum Atlas: Chemoarchitecture and Cytoarchitecture Paired to MRI. Agostinelli LJ, Seaman SC, Saper CB, Fykstra DP, Hefti MM, Koscik TR, Dlouhy BJ, Bassuk AG. J Neurosci. 2023 Jan 11;43(2):221-239. doi: 10.1523/JNEUROSCI.0587-22.2022. Epub 2022 Nov 28.

Week of January 17, 2023
Avasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in head and neck cancer patients. Mapuskar KA, Vasquez Martinez G, Pulliam CF, Petronek MS, Steinbach EJ, Monga V, Furqan M, Jetton JG, Saunders DP, Pearce A, Davidson S, Pitre L, Dunlap NE, Fairbanks R, Lee CM, Mott SL, Bodeker KL, Cl H, Buatti JM, Anderson CM, Beardsley RA, Holmlund JT, Zepeda-Orozco D, Spitz DR, Allen BG. Redox Biol. 2023 Jan 3;60:102599. doi: 10.1016/j.redox.2022.102599. Online ahead of print.

Breast cancer patients from the Midwest region of the United States have reduced levels of short-chain fatty acid-producing gut bacteria. Shrode RL, Knobbe JE, Cady N, Yadav M, Hoang J, Cherwin C, Curry M, Garje R, Vikas P, Sugg S, Phadke S, Filardo E, Mangalam AK. Sci Rep. 2023 Jan 11;13(1):526. doi: 10.1038/s41598-023-27436-3.

Week of January 10, 2023
CD47 halts Ptpn6-deficient neutrophils from provoking lethal inflammation. Mazgaeen L, Yorek M, Saini S, Vogel P, Meyerholz DK, Kanneganti TD, Gurung P. Sci Adv. 2023 Jan 6;9(1):eade3942. doi: 10.1126/sciadv.ade3942. Epub 2023 Jan 6.

AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes. Marques-da-Silva C, Poudel B, Baptista RP, Peissig K, Hancox LS, Shiau JC, Pewe LL, Shears MJ, Kanneganti TD, Sinnis P, Kyle DE, Gurung P, Harty JT, Kurup SP. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2210181120. doi: 10.1073/pnas.2210181120. Epub 2023 Jan 3.

Week of January 3, 2023
Rigid respiration: fulminant pulmonary fibrosis after COVID-19. Meyerholz DK. EBioMedicine. 2022 Dec 27;87:104428. doi: 10.1016/j.ebiom.2022.104428. Online ahead of print.

Week of December 27, 2022
Avelumab-Induced Scleroderma in a Patient with Metastatic Squamous Cell Carcinoma of the Lung. Dobrzynski JL, Vest BE, Swick BL. Case Rep Dermatol Med. 2022 Dec 15;2022:5360113. doi: 10.1155/2022/5360113. eCollection 2022.

Cryopreservation of Plasmodium Sporozoites. Bowers C, Hancox L, Peissig K, Shiau JC, Vantaux A, Witkowski B, Phal S, Maher SP, Harty JT, Kyle DE, Kurup SP. Pathogens. 2022 Dec 7;11(12):1487. doi: 10.3390/pathogens11121487.

Acute myeloid leukemia resistant to venetoclax-based therapy: What does the future hold? Dhakal P, Bates M, Tomasson MH, Sutamtewagul G, Dupuy A, Bhatt VR. Blood Rev. 2022 Dec 1:101036. doi: 10.1016/j.blre.2022.101036. Online ahead of print.

Development and Validation of a Western Blot Method to Quantify Mini-Dystrophin in Human Skeletal Muscle Biopsies. Soderstrom CI, Larsen J, Owen C, Gifondorwa D, Beidler D, Yong FH, Conrad P, Neubert H, Moore SA, Hassanein M. AAPS J. 2022 Dec 20;25(1):12. doi: 10.1208/s12248-022-00776-0.

Current Laboratory Testing Practices for Assessment of ERBB2/HER2 in Endometrial Serous Carcinoma and Colorectal Carcinoma. Hagemann IS, Bridge JA, Tafe LJ, Hameed MR, Moncur JT, Bellizzi AM, Dolan M, Vasalos P, Kane ME, Souers RJ, Yemelyanova A. Arch Pathol Lab Med. 2022 Dec 20. doi: 10.5858/arpa.2022-0229-CP. Online ahead of print.

Week of December 20, 2022
Comparison of platelet antibody screen, crossmatching and HLA antibody testing in patients refractory to platelet transfusions. Chapman JM, Wendt L, Knudson CM. Transfus Apher Sci. 2022 Dec 10:103622. doi: 10.1016/j.transci.2022.103622. Online ahead of print.

A tale of two peripheral blood CD34+ cell counts: Evaluation of unexpectedly high values prior to peripheral stem cell collection. Rogers KJ, Parsons MG, Strouse CS, Farooq U, Schlueter AJ. Transfus Apher Sci. 2022 Dec 14:103624. doi: 10.1016/j.transci.2022.103624. Online ahead of print.

SETDB1: a perspective into immune cell function and cancer immunotherapy. Johnson E, Salari K, Yang S. Immunology. 2022 Dec 16. doi: 10.1111/imm.13619. Online ahead of print.

The BBSome regulates mitochondria dynamics and function. Guo DF, Merrill RA, Qian L, Hsu Y, Zhang Q, Lin Z, Thedens DR, Usachev YM, Grumbach I, Sheffield VC, Strack S, Rahmouni K. Mol Metab. 2022 Dec 10:101654. doi: 10.1016/j.molmet.2022.101654. Online ahead of print.

Coronavirus disease 2019 (COVID-19) incidence after exposures in shared patient rooms in a tertiary-care center in Iowa, July 2020-May 2021. Trannel AM, Kobayashi T, Dains A, Abosi OJ, Jenn KE, Meacham H, Sheeler LL, Etienne W, Kukla ME, Alsuhaibani M, Holley S, Strandberg K, Marra AR, Kritzman J, Ford B, Wellington M, Diekema DJ, Salinas JL. Infect Control Hosp Epidemiol. 2022 Dec;43(12):1910-1913. doi: 10.1017/ice.2021.313. Epub 2021 Jul 12.

Week of December 13, 2022
Selective androgen receptor modulator microparticle formulation reverses muscle hyperalgesia in a mouse model of widespread muscle pain. Lesnak JB, Nakhla DS, Plumb AN, McMillan A, Saha S, Gupta N, Xu Y, Phruttiwanichakun P, Rasmussen L, Meyerholz DK, Salem AK, Sluka KA. Pain. 2022 Dec 9. doi: 10.1097/j.pain.0000000000002841. Online ahead of print.

Practice Patterns for Reporting Digestive System Neuroendocrine Neoplasms: Results from a Large, Comprehensive International Survey. Karamchandani DM, Cox B, La Rosa S, Bellizzi AM, Shi C, Gonzalez RS. Histopathology. 2022 Dec 12. doi: 10.1111/his.14851. Online ahead of print.

Association between job role and coronavirus disease 2019 (COVID-19) among healthcare personnel, Iowa, 2021. Kobayashi T, Trannel A, Heinemann J, Marra AR, Etienne W, Abosi OJ, Holley S, Dains A, Jenn KE, Meacham H, Schuessler BA, Wendt L, Ten Eyck P, Hanna B, Salinas JL, Hartley PG, Ford B, Wellington M, Brust KB, Diekema DJ. Antimicrob Steward Healthc Epidemiol. 2022 Dec 1;2(1):e188. doi: 10.1017/ash.2022.349. eCollection 2022.

Enhancing progestin therapy via HDAC inhibitors in endometrial cancer. Li Y, Zhou W, Li L, Li JW, Li T, Huang C, Lazaro-Camp VJ, Kavlashvili T, Zhang Y, Reyes H, Li Y, Dai D, Zhu W, Meng X, Leslie KK, Yang S. Am J Cancer Res. 2022 Nov 15;12(11):5029-5048. eCollection 2022.

Blood culture practices in patients with a central line at an academic medical center-Iowa, 2020. Kovoor E, Kobayashi T, Sheeler LL, Trannel A, Etienne W, Abosi O, Holley S, Dains A, Jenn KE, Meacham H, Hanna B, Marra AR, Parsons M, Ford B, Wellington M, Diekema DJ, Salinas JL. Antimicrob Steward Healthc Epidemiol. 2022 Apr 13;2(1):e64. doi: 10.1017/ash.2022.45. eCollection 2022.

Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE). Fitzpatrick MA, Suda KJ, Ramanathan S, Wilson G, Poggensee L, Evans M, Jones MM, Pfeiffer CD, Klutts JS, Perencevich E, Rubin M, Evans CT; QUERI CARRIAGE Program. Antimicrob Steward Healthc Epidemiol. 2022 Jun 2;2(1):e88. doi: 10.1017/ash.2021.220. eCollection 2022.

Inefficient Recovery of Repeatedly Stimulated Memory CD8 T Cells after Polymicrobial Sepsis Induction Leads to Changes in Memory CD8 T Cell Pool Composition. Moioffer SJ, Berton RR, McGonagill PW, Jensen IJ, Griffith TS, Badovinac VP. J Immunol. 2022 Dec 7:ji2200676. doi: 10.4049/jimmunol.2200676. Online ahead of print.

In response to Joubeh and Singh: Allergic reactions to platelets; to B or not to B? Rossi S, Wendt L, Ballas Z, Knudson CM. Transfusion. 2022 Dec;62(12):2655-2656. doi: 10.1111/trf.17161.

Week of December 6, 2022
Adolescent- and adult-initiated alcohol exposure in mice differentially promote tumorigenesis and metastasis of breast cancer.Xu M, Li H, Chen D, Wu H, Wen W, Xu H, Frank J, Chen G, Luo J. Alcohol Clin Exp Res. 2022 Dec 3. doi: 10.1111/acer.14986. Online ahead of print.

Cardiac Adverse Events Associated With Chemo-Radiation Versus Chemotherapy for Resectable Stage III Non-Small-Cell Lung Cancer: A Surveillance, Epidemiology and End Results-Medicare Study. Herbach E, O'Rorke MA, Carnahan RM, McDowell BD, Allen B, Grumbach I, London B, Smith BJ, Spitz DR, Seaman A, Chrischilles EA. J Am Heart Assoc. 2022 Dec 1:e027288. doi: 10.1161/JAHA.122.027288. Online ahead of print.

Proceedings From the ASCO/College of American Pathologists Immune Checkpoint Inhibitor Predictive Biomarker Summit. Hayes DF, Herbst RS, Myles JL, Topalian SL, Yohe SL, Aronson N, Bellizzi AM, Basu Roy U, Bradshaw G, Edwards RH, El-Gabry EA, Elvin J, Gajewski TF, McShane LM, Oberley M, Philip R, Rimm DL, Rosenbaum JN, Rubin EH, Schlager L, Sherwood SW, Stewart M, Taube JM, Thurin M, Vasalos P, Laser J. JCO Precis Oncol. 2022 Nov;6:e2200454. doi: 10.1200/PO.22.00454.

Ceftolozane/Tazobactam Activity Against Drug-Resistant Pseudomonas aeruginosa and Enterobacterales Causing Healthcare-Associated Infections in Eight Asian Countries: Report from an Antimicrobial Surveillance Program (2016-2018). Pfaller M, Shortridge D, Chen WT, Sader H, Castanheira M. Infect Drug Resist. 2022 Nov 22;15:6739-6753. doi: 10.2147/IDR.S387097. eCollection 2022.

Week of November 29, 2022
Human Brainstem and Cerebellum Atlas- Chemoarchitecture and Cytoarchitecture Paired to MRI. Agostinelli LJ, Seaman SC, Saper CB, Fykstra D, Hefti MM, Koscik TR, Dlouhy BJ, Bassuk AG. J Neurosci. 2022 Nov 28:JN-RM-0587-22. doi: 10.1523/JNEUROSCI.0587-22.2022. Online ahead of print.

Preclinical Models of Neuroendocrine Neoplasia. Sedlack AJH, Saleh-Anaraki K, Kumar S, Ear PH, Lines KE, Roper N, Pacak K, Bergsland E, Quelle DE, Howe JR, Pommier Y, Del Rivero J. Cancers (Basel). 2022 Nov 17;14(22):5646. doi: 10.3390/cancers14225646.

Role of the gut microbiome in multiple sclerosis: From etiology to therapeutics. Shahi SK, Yadav M, Ghimire S, Mangalam AK. Int Rev Neurobiol. 2022;167:185-215. doi: 10.1016/bs.irn.2022.06.001. Epub 2022 Jun 25.

Miyoshi Muscular Dystrophy Due to Novel Splice Site Variants in DYSF Gene. Bryant G, Moore SA, Nix JS, Rice G, Gokden M, Veerapandiyan A. Child Neurol Open. 2022 Nov 16;9:2329048X221140298. doi: 10.1177/2329048X221140298. eCollection 2022 Jan-Dec.

Molecular Epidemiological Investigations of Localized SARS-CoV-2 Outbreaks-Utility of Public Algorithms. Bilal MY, Klutts JS. Epidemiologia (Basel). 2022 Sep 19;3(3):402-411. doi: 10.3390/epidemiologia3030031.

Rapid cytologic diagnosis of subcutaneous fat necrosis of the newborn. Harview CL, Chen A, Stone M, Fairley J. Pediatr Dermatol. 2022 Nov 21. doi: 10.1111/pde.15194. Online ahead of print.

Prevalence of maternal obesity at delivery and association with maternal and neonatal outcomes. Castaneda C, Marsden K, Maxwell T, Ten Eyck P, Kuwaye D, Kenne KA, Merryman AS, Steffen HA, Swartz SR, Merrill AE, Krasowski MD, Jackson JB, Rysavy MB. J Matern Fetal Neonatal Med. 2022 Dec;35(25):8544-8551. doi: 10.1080/14767058.2021.1988563. Epub 2021 Oct 12.

Week of November 22, 2022
Further prognostic stratification of intestinal type of gastric adenocarcinoma by CDX2 expression pattern. Hao Y, Liu BL, Liang Y, Xiong Y, Polydorides AD, Ward S. Hum Pathol. 2022 Nov 17:S0046-8177(22)00262-3. doi: 10.1016/j.humpath.2022.11.005. Online ahead of print.

Refractory Pediatric Fibrostenotic Eosinophilic Esophagitis Treated With Dupilumab. Gangadharan Nambiar G, Rahhal R, Davis BP, Xiong Y, Cheung D. ACG Case Rep J. 2022 Nov 11;9(11):e00887. doi: 10.14309/crj.0000000000000887. eCollection 2022 Nov.

ASO Visual Abstract: Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms-A Systematic Review and Meta-Analysis. Ziogas IA, Tasoudis PT, Borbon LC, Sherman SK, Breheny PJ, Chandrasekharan C, Dillon JS, Bellizzi AM, Howe JR. Ann Surg Oncol. 2022 Nov 15. doi: 10.1245/s10434-022-12796-3. Online ahead of print.

SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways. Verma AK, Zheng J, Meyerholz DK, Perlman S. JCI Insight. 2022 Nov 15:e160277. doi: 10.1172/jci.insight.160277. Online ahead of print.

Week of November 15, 2022
Propofol-induced interference with activated partial thromboplastin time-based monitoring of therapeutic heparin anticoagulation. Negaard BJ, Hobbs R, Frye JR, Merrill AE. Am J Health Syst Pharm. 2022 Nov 12:zxac337. doi: 10.1093/ajhp/zxac337. Online ahead of print.

Keeping T cell memories in mind. Mix MR, Harty JT. Trends Immunol. 2022 Nov 8:S1471-4906(22)00209-5. doi: 10.1016/j.it.2022.10.001. Online ahead of print.

Week of November 8, 2022
Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy. Allen BD, Alaghband Y, Kramár EA, Ru N, Petit B, Grilj V, Petronek MS, Pulliam CF, Kim RY, Doan NL, Baulch JE, Wood MA, Bailat C, Spitz DR, Vozenin MC, Limoli CL. Neuro Oncol. 2022 Nov 5:noac248. doi: 10.1093/neuonc/noac248. Online ahead of print.

Endogenous SOD2 (Superoxide Dismutase) Regulates Platelet-Dependent Thrombin Generation and Thrombosis During Aging. Sonkar VK, Eustes AS, Ahmed A, Jensen M, Solanki MV, Swamy J, Kumar R, Fidler TP, Houtman JCD, Allen BG, Spitz DR, Abel ED, Dayal S. Arterioscler Thromb Vasc Biol. 2022 Nov 3. doi: 10.1161/ATVBAHA.121.317735. Online ahead of print.

Complex Sweat Gland Hamartoma: A Case Report. Skopec Z, Berrebi K, Stone M, Liu V. J Cutan Pathol. 2022 Nov 2. doi: 10.1111/cup.14350. Online ahead of print.

Week of November 1, 2022
Long-Lasting Protection Induced by a Polyanhydride Nanovaccine against Respiratory Syncytial Virus in an Outbred Mouse Model. Stephens LM, Ross KA, McLellan JS, Narasimhan B, Varga SM. J Virol. 2022 Oct 31:e0150222. doi: 10.1128/jvi.01502-22. Online ahead of print.

Rates of Antimicrobial Resistance With Extended Oral Antibiotic Prophylaxis After Total Joint Arthroplasty. Carender CN, Sekar P, Prasidthrathsint K, DeMik DE, Brown TS, Bedard NA. Arthroplast Today. 2022 Oct 25;18:112-118. doi: 10.1016/j.artd.2022.09.007. eCollection 2022 Dec.

A Case of Secondary Hemophagocytic Lymphohistiocytosis Presenting with Severe Dyserythropoeisis in a Patient with Autoimmune Hemolysis. Rogers KJ, Bhagavathi S. Case Rep Hematol. 2022 Oct 19;2022:8505823. doi: 10.1155/2022/8505823. eCollection 2022.

A live single-cycle RSV vaccine expressing prefusion F protein. Lamichhane P, Schmidt ME, Terhüja M, Varga SM, Snider TA, Rostad CA, Oomens AGP. Virology. 2022 Oct 15;577:51-64. doi: 10.1016/j.virol.2022.10.003. Online ahead of print.

Isoflavone consumption reduces inflammation through modulation of phenylalanine and lipid metabolism. Shrode RL, Cady N, Jensen SN, Borcherding N, Mangalam AK. Metabolomics. 2022 Oct 26;18(11):84. doi: 10.1007/s11306-022-01944-1.

Activities of Manogepix and Comparators against 1,435 Recent Fungal Isolates Collected during an International Surveillance Program (2020). Pfaller MA, Huband MD, Rhomberg PR, Bien PA, Castanheira M. Antimicrob Agents Chemother. 2022 Oct 26:e0102822. doi: 10.1128/aac.01028-22. Online ahead of print.

Succinate prodrugs as treatment for acute metabolic crisis during fluoroacetate intoxication in the rat. Piel S, Janowska JI, Ward JL, McManus MJ, Aronowitz DI, Janowski PK, Starr J, Hook JN, Hefti MM, Clayman CL, Elmér E, Hansson MJ, Jang DH, Karlsson M, Ehinger JK, Kilbaugh TJ. Mol Cell Biochem. 2022 Oct 25. doi: 10.1007/s11010-022-04589-9. Online ahead of print.

TRAF3IP2-IL-17 Axis Strengthens the Gingival Defense against Pathogens. Zhang J, Sun L, Withanage MHH, Ganesan SM, Williamson MA, Marchesan JT, Jiao Y, Teles FR, Yu N, Liu Y, Wu D, Moss KL, Mangalam AK, Zeng E, Lei YL, Zhang S. J Dent Res. 2022 Oct 24:220345221123256. doi: 10.1177/00220345221123256. Online ahead of print.

Week of October 25, 2022
Use of compressed sensing to expedite high-throughput diagnostic testing for COVID-19 and beyond. Waldstein KA, Yi J, Cho M, Mudumbai R, Wu X, Varga SM, Xu W. PLoS Comput Biol. 2022 Oct 24;18(10):e1010629. doi: 10.1371/journal.pcbi.1010629. Online ahead of print.

Tissue resident memory T cells- A new benchmark for the induction of vaccine-induced mucosal immunity. Hassert M, Harty JT. Front Immunol. 2022 Oct 4;13:1039194. doi: 10.3389/fimmu.2022.1039194. eCollection 2022.

SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Zhu EY, Riordan JD, Vanneste M, Henry MD, Stipp CS, Dupuy AJ. NPJ Precis Oncol. 2022 Oct 21;6(1):74. doi: 10.1038/s41698-022-00310-7.

Plasticity of Cerebral Microvascular Structure and Mechanics During Hypertension and Following Recovery of Arterial Pressure. Sabharwal R, Chapleau MW, Gerhold TD, Baumbach GL, Faraci FM. Am J Physiol Heart Circ Physiol. 2022 Oct 21. doi: 10.1152/ajpheart.00292.2022. Online ahead of print.

Anatomic pathology quality assurance: Developing an LIS based tracking and documentation module for intradepartmental consultations. Dundar B, Chen SJ, Blau JL, Anand Rajan KD, Samuelson MI, Greek-Lippe ML, Lake KS, Robinson RA. J Pathol Inform. 2022 Jun 24;13:100109. doi: 10.1016/j.jpi.2022.100109. eCollection 2022.

The genome-wide DNA methylation profiles among neurosurgery patients with and without post-operative delirium. Yamanashi T, Crutchley KJ, Wahba NE, Nagao T, Marra PS, Akers CC, Sullivan EJ, Iwata M, Howard MA 3rd, Cho HR, Kawasaki H, Hughes CG, Pandharipande PP, Hefti MM, Shinozaki G. Psychiatry Clin Neurosci. 2022 Oct 20. doi: 10.1111/pcn.13495. Online ahead of print.

Delays in melanoma presentation during the COVID-19 pandemic: A nationwide multi-institutional cohort study. Trepanowski N, Chang MS, Zhou G, Ahmad M, Berry EG, Bui K, Butler WH, Chu EY, Curiel-Lewandrowski C, Dellalana LE, Ellis DL, Freeman SC, Gorrepati PL, Grossman D, Gyurdzhyan S, Kanetsky PA, Ong King AL, Kolla AM, Lian CG, Lin JY, Liu V, Lowenthal A, McCoy KN, Munjal A, Myrdal CN, Perkins S, Powers JG, Rauck C, Smart TC, Stein JA, Venna S, Walsh ME, Wang JY, Leachman SA, Swetter SM, Hartman RI. J Am Acad Dermatol. 2022 Nov;87(5):1217-1219. doi: 10.1016/j.jaad.2022.06.031. Epub 2022 Jun 20.

Week of October 18, 2022
Biobehavioral factors predict an exosome biomarker of ovarian carcinoma disease progression. Lutgendorf SK, Thaker PH, Goodheart MJ, Arevalo JMG, Chowdhury MA, Noble AE, Dahmoush L, Slavich GM, Penedo FJ, Sood AK, Cole SW. Cancer. 2022 Oct 17. doi: 10.1002/cncr.34496. Online ahead of print.

A thorny matter: spur cell anemia. Sharma R, Holman CJ, Brown KE. Ann Hepatol. 2022 Oct 11:100771. doi: 10.1016/j.aohep.2022.100771. Online ahead of print.

Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer. Li Y, Zhou W, Meng X, Murray SD, Li L, Fronk A, Lazaro-Camp VJ, Wen KK, Wu M, Dupuy A, Leslie KK, Yang S. Cancers (Basel). 2022 Oct 6;14(19):4883. doi: 10.3390/cancers14194883.

Manipulation of Redox Metabolism using Pharmacologic Ascorbate Opens a Therapeutic Window for Radio-sensitization by ATM Inhibitors in Colorectal Cancer. Callaghan CM, Abukhiran IM, Masaadeh A, Van Rheeden RV, Kalen AL, Rodman SN 3rd, Petronek MS, Mapuskar KA, George BN, Coleman MC, Goswami PC, Allen BG, Spitz DR, Caster JM. Int J Radiat Oncol Biol Phys. 2022 Oct 10:S0360-3016(22)03438-1. doi: 10.1016/j.ijrobp.2022.10.012. Online ahead of print.

Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism. Gutierrez WR, Scherer A, Rytlewski JD, Laverty EA, Sheehan AP, McGivney GR, Brockman QR, Knepper-Adrian V, Roughton GA, Quelle DE, Gordon DJ, Monga V, Dodd RD. JCI Insight. 2022 Oct 13:e159419. doi: 10.1172/jci.insight.159419. Online ahead of print.

Surgical Management of G3 Gastroenteropancreatic Neuroendocrine Neoplasms: A Systematic Review and Meta-analysis. Ziogas IA, Tasoudis PT, Borbon LC, Sherman SK, Breheny PJ, Chandrasekharan C, Dillon JS, Bellizzi AM, Howe JR. Ann Surg Oncol. 2022 Oct 13. doi: 10.1245/s10434-022-12643-5. Online ahead of print.

Nicotine and Tobacco Alkaloid Testing and Challenges. Snozek CLH, McMillin GA, Nwosu A, Dizon A, Krasowski MD. Arch Pathol Lab Med. 2022 Oct 10. doi: 10.5858/arpa.2022-0094-CP. Online ahead of print.

Influenza-Induced CD103+ T Resident Memory Cells Exhibit Enhanced Functional Avidity over CD103- Memory T Cells in the Mediastinal Lymph Node. Crooks SD, Varga SM, Harty JT. Immunohorizons. 2022 Oct 11;6(10):705-715. doi: 10.4049/immunohorizons.2100074.

Evaluation of the Post-Antifungal Effect of Rezafungin and Micafungin against Candida albicans, Candida parapsilosis and Candida glabrata. Carvalhaes CG, Rhomberg PR, Pfaller MA, Locke JB, Castanheira M. Mycoses. 2022 Nov;65(11):1040-1044. doi: 10.1111/myc.13490. Epub 2022 Jul 18.

Week of October 11, 2022
Distribution of High-Sensitivity Cardiac Troponin and N-Terminal Pro-Brain Natriuretic Peptide in Healthy Transgender People. Greene DN, Schmidt RL, Christenson RH, Rongitsch J, Imborek KL, Rebuck H, Lorey TS, Saenger AK, Krasowski MD. JAMA Cardiol. 2022 Oct 5. doi: 10.1001/jamacardio.2022.3299. Online ahead of print.

Effectiveness and Optimal Duration of Adjunctive Rifampin Treatment in the Management of Staphylococcus aureus Prosthetic Joint Infections After Debridement, Antibiotics, and Implant Retention. Suzuki H, Goto M, Nair R, Livorsi DJ, Sekar P, Ohl ME, Diekema DJ, Perencevich EN, Alexander B, Jones MP, McDaniel JS, Schweizer ML. Open Forum Infect Dis. 2022 Sep 12;9(9):ofac473. doi: 10.1093/ofid/ofac473. eCollection 2022 Sep.

Clinical Decision Support Systems to Reduce Unnecessary Clostridioides difficile Testing Across Multiple Hospitals. Rock C, Abosi O, Bleasdale S, Colligan E, Diekema DJ, Dullabh P, Gurses AP, Heaney-Huls K, Jacob JT, Kandiah S, Lama S, Leekha S, Mayer J, Mena Lora AJ, Morgan DJ, Osei P, Pau S, Salinas JL, Spivak E, Wenzler E, Cosgrove SE. Clin Infect Dis. 2022 Sep 30;75(7):1187-1193. doi: 10.1093/cid/ciac074.

Week of October 4, 2022
Cbl-b restrains priming of pathogenic Th17 cells via the inhibition of IL-6 production by macrophages. Zeng Q, Tang N, Ma Y, Guo H, Zhao Y, Tang R, Yan C, Ouyang S, Langdon WY, Yang H, O'Brien MC, Zhang J. iScience. 2022 Sep 15;25(10):105151. doi: 10.1016/j.isci.2022.105151. eCollection 2022 Oct 21.

Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation. Ghimire S, Cady NM, Lehman P, Peterson SR, Shahi SK, Rashid F, Giri S, Mangalam AK. Gut Microbes. 2022 Jan-Dec;14(1):2127446. doi: 10.1080/19490976.2022.2127446.

Orf Virus in Humans: Case Series and Clinical Review. Thompson HJ, Harview CL, Swick B, Powers JG. Cutis. 2022 Jul;110(1):48-52. doi: 10.12788/cutis.0567.

TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies. Basisty N, Shulman N, Wehrfritz C, Marsh AN, Shah S, Rose J, Ebert S, Miller M, Dai DF, Rabinovitch PS, Adams CM, MacCoss MJ, MacLean B, Schilling B. J Proteome Res. 2022 Sep 27. doi: 10.1021/acs.jproteome.2c00173. Online ahead of print.

Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis. Shahi SK, Ghimire S, Lehman P, Mangalam AK. Front Immunol. 2022 Sep 9;13:966417. doi: 10.3389/fimmu.2022.966417. eCollection 2022.

Week of September 27, 2022
Multicenter Collaborative Study of the Interaction of Antifungal Combinations against Candida Spp. by Loewe Additivity and Bliss Independence-Based Response Surface Analysis. Meletiadis J, Andes DR, Lockhart SR, Ghannoum MA, Knapp CC, Ostrosky-Zeichner L, Pfaller MA, Chaturvedi V, Walsh TJ. J Fungi (Basel). 2022 Sep 16;8(9):967. doi: 10.3390/jof8090967.

Congenital Neutropenia with Specific Granulocyte Deficiency Caused by Novel Double Heterozygous SMARCD2 Mutations. Ibrahim A, Sharathkumar A, McLaughlin H, Claassen D, Bhagavathi S. Hematol Rep. 2022 Sep 9;14(3):270-275. doi: 10.3390/hematolrep14030038.

Akt-2 Is a Potential Therapeutic Target for Disseminated Candidiasis. Huang L, Ma Y, Guo H, Tang N, Ouyang S, Nuro-Gyina P, Tao L, Liu Y, O'Brien MC, Langdon WY, Zhang J. J Immunol. 2022 Sep 1;209(5):991-1000. doi: 10.4049/jimmunol.2101003. Epub 2022 Aug 5.

Week of September 20, 2022
SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. El-Kafrawy SA, Odle A, Abbas AT, Hassan AM, Abdel-Dayem UA, Qureshi AK, Wong LR, Zheng J, Meyerholz DK, Perlman S, Zumla A, Azhar EI. PLoS Pathog. 2022 Sep 19;18(9):e1010782. doi: 10.1371/journal.ppat.1010782. eCollection 2022 Sep.

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Vaishnavi A, Juan J, Jacob M, Stehn C, Gardner EE, Scherzer MT, Schuman S, van Veen JE, Murphy B, Hackett CS, Dupuy AJ, Chmura SA, van der Weyden L, Newberg JY, Liu A, Mann K, Rust AG, Weiss WA, Kinsey CG, Adams DJ, Grossmann A, Mann MB, McMahon M. Cancer Res. 2022 Sep 16:CAN-21-3214. doi: 10.1158/0008-5472.CAN-21-3214. Online ahead of print.

Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment. Sponagel J, Jones JK, Frankfater C, Zhang S, Tung O, Cho K, Tinkum KL, Gass H, Nunez E, Spitz DR, Chinnaiyan P, Schaefer J, Patti GJ, Graham MS, Mauguen A, Grkovski M, Dunphy MP, Krebs S, Luo J, Rubin JB, Ippolito JE. Med (N Y). 2022 Sep 8:S2666-6340(22)00365-8. doi: 10.1016/j.medj.2022.08.005. Online ahead of print.

Evolving mucocutaneous eruptions following chemotherapy. Chen A, Patrick AP, Sharif-Sidi Z, Liu V, Fairley JA. JAAD Case Rep. 2022 Aug 10;28:67-70. doi: 10.1016/j.jdcr.2022.08.004. eCollection 2022 Oct.

Metastatic extraskeletal myxoid chondrosarcoma presenting as a forehead mass. Tan KW, Jamison AS, Swick BL, Ferguson NN. JAAD Case Rep. 2022 Aug 11;28:40-43. doi: 10.1016/j.jdcr.2022.08.012. eCollection 2022 Oct.

Days of Antibiotic Spectrum Coverage: A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2022 Sep 10;75(4):567-576. doi: 10.1093/cid/ciab1034.