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Recent Publications

Week of July 7, 2020
Illuminating COVID-19 lung disease through autopsy studies. Meyerholz DK, McCray PB Jr. EBioMedicine. 2020 Jul 3;57:102865. doi: 10.1016/j.ebiom.2020.102865. [Epub ahead of print] No abstract available.

Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE. Zheng J, Sariol A, Meyerholz D, Zhang Q, Abrahante Lloréns JE, Narumiya S, Perlman S. J Autoimmun. 2020 Jul 2:102508. doi: 10.1016/j.jaut.2020.102508. [Epub ahead of print].

Liver metastases from pituitary carcinomas mimicking visceral well-differentiated neuroendocrine tumors: a series of four cases. Venable ER, Kerr SE, Lopes MBS, Jones KA, Bellizzi AM, Mounajjed T, Raghunathan A, Hamidi O, Halfdanarson TR, Ryder M, Graham RP. Diagn Pathol. 2020 Jul 4;15(1):81. doi: 10.1186/s13000-020-00997-x.

Activity of ceftolozane-tazobactam and comparators when tested against bacterial surveillance isolates collected from patients at risk of infections caused by resistant gram-negative pathogens. Pfaller MA, Shortridge D, Arends SJR, Duncan LR, Streit JM, Flamm RK. Diagn Microbiol Infect Dis. 2020 Jun 6;98(1):115101. doi: 10.1016/j.diagmicrobio.2020.115101. [Epub ahead of print].

A genetic screen to identify gain- and loss-of-function modifications that enhance T-cell infiltration into tumors. Rogers LM, Wang Z, Mott SL, Dupuy AJ, Weiner GJ. Cancer Immunol Res. 2020 Jul 1. pii: canimm.0056.2020. doi: 10.1158/2326-6066.CIR-20-0056. [Epub ahead of print].

Input-output connections of LJA5 prodynorphin neurons. Agostinelli LJ, Mix MR, Hefti MM, Scammell TE, Bassuk AG. J Comp Neurol. 2020 Jun 30. doi: 10.1002/cne.24974. [Epub ahead of print].

Week of June 30, 2020
Clinical image: chronic skin ulcers in a patient with rheumatoid arthritis on immunosuppressant therapy. Kobayashi T, Swick BL, Cho C. Clin Rheumatol. 2020 Jun 26. doi: 10.1007/s10067-020-05251-9. [Epub ahead of print] No abstract available.

Characteristics of Nontuberculous Mycobacterial Infections at a Midwestern Tertiary Hospital: A Retrospective Study of 365 Patients. Hannah CE, Ford BA, Chung J, Ince D, Wanat KA. Open Forum Infect Dis. 2020 May 25;7(6):ofaa173. doi: 10.1093/ofid/ofaa173. eCollection 2020 Jun.

Peripherally induced brain tissue-resident memory CD8+ T cells mediate protection against CNS infection. Urban SL, Jensen IJ, Shan Q, Pewe LL, Xue HH, Badovinac VP, Harty JT. Nat Immunol. 2020 Jun 22. doi: 10.1038/s41590-020-0711-8. [Epub ahead of print].

New Insights into the Immune System Using Dirty Mice. Hamilton SE, Badovinac VP, Beura LK, Pierson M, Jameson SC, Masopust D, Griffith TS. J Immunol. 2020 Jul 1;205(1):3-11. doi: 10.4049/jimmunol.2000171. Review.

Week of June 23, 2020
RPL-6: An Achilles Needle in the Malaria Haystack? Drewry LL, Harty JT. Trends Parasitol. 2020 Jun 18. pii: S1471-4922(20)30162-8. doi: 10.1016/j.pt.2020.06.001. [Epub ahead of print].

A Dramatic Presentation of Immune-Mediated Necrotizing Myopathy. Diel RJ, Hannah CE, Moore SA, Bettendorf B. J Clin Rheumatol. 2020 Jun 17. doi: 10.1097/RHU.0000000000001443. [Epub ahead of print] No abstract available.

Week of June 16, 2020
Immune Autoregulatory CD8 T Cells Require IFN-γ Responsiveness to Optimally Suppress Central Nervous System Autoimmunity. Boyden AW, Brate AA, Stephens LM, Karandikar NJ. J Immunol. 2020 Jun 12. pii: ji2000211. doi: 10.4049/jimmunol.2000211. [Epub ahead of print].

What Every Neuropathologist Needs to Know: The Muscle Biopsy. Nix JS, Moore SA. J Neuropathol Exp Neurol. 2020 Jun 11. pii: nlaa046. doi: 10.1093/jnen/nlaa046. [Epub ahead of print].

Randomized controlled trial comparing the Franseen needle with a Fork-tip needle for EUS-guided fine-needle biopsy. Ashat M, Klair JS, Rooney SL, Vishal SJ, Jensen C, Murali AR, Sahar N, El-Abiad R, Gerke H. Gastrointest Endosc. 2020 Jun 8. pii: S0016-5107(20)34407-2. doi: 10.1016/j.gie.2020.05.057. [Epub ahead of print].

Vertebral hemangiomas: Diagnosis and management. A single center experience. Teferi N, Abukhiran I, Noeller J, Helland LC, Bathla G, Ryan EC, Nourski KV, Hitchon PW. Clin Neurol Neurosurg. 2020 Mar;190:105745. doi: 10.1016/j.clineuro.2020.105745. Epub 2020 Feb 19.Clin Neurol Neurosurg. 2020.

Week of June 9, 2020
Isolated Histoplasma Tenosynovitis in a Patient on Adalimumab. Rieth JM, Chen SJT, Bennett DL, Suneja M. Mayo Clin Proc. 2020 Jun;95(6):1212. doi: 10.1016/j.mayocp.2020.02.023. No abstract available.

Occupational Tuberculosis Exposures and Conversion Rates Can Guide Deimplementation of Annual Tuberculosis Skin Test Screening. Kobayashi T, Meacham H, Alsuhaibani M, Holley S, Marra AR, Edmond MB, Diekema DJ, Hartley PG, Salinas JL. Infect Control Hosp Epidemiol. 2020 Jun 2:1-2. doi: 10.1017/ice.2020.205. [Epub ahead of print] No abstract available.

Week of June 2, 2020
NIH funding trends to US medical schools from 2009 to 2018. Noble P, Ten Eyck P, Roskoski R Jr, Jackson JB. PLoS One. 2020 Jun 1;15(6):e0233367. doi: 10.1371/journal.pone.0233367. eCollection 2020.

Interpretable multimodal deep learning for real-time pan-tissue pan-disease pathology search on social media. Schaumberg AJ, Juarez-Nicanor WC, Choudhury SJ, Pastrián LG, Pritt BS, Prieto Pozuelo M, Sotillo Sánchez R, Ho K, Zahra N, Sener BD, Yip S, Xu B, Annavarapu SR, Morini A, Jones KA, Rosado-Orozco K, Mukhopadhyay S, Miguel C, Yang H, Rosen Y, Ali RH, Folaranmi OO, Gardner JM, Rusu C, Stayerman C, Gross J, Suleiman DE, Sirintrapun SJ, Aly M, Fuchs TJ. Mod Pathol. 2020 May 28. doi: 10.1038/s41379-020-0540-1. [Epub ahead of print].

Data on the relationship of signal-to-cutoff ratio of two HIV antigen/antibody combination assays to subsequent confirmation of HIV-1 infection in a low-prevalence population. Hodgson CK, Krasowski MD, Ford BA. Data Brief. 2020 May 16;31:105707. doi: 10.1016/j.dib.2020.105707. eCollection 2020 Aug.

Week of May 26, 2020
Frontline Science: CD40 Signaling Restricts RNA Virus Replication in Mϕs, Leading to Rapid Innate Immune Control of Acute Virus Infection. Rogers KJ, Shtanko O, Stunz LL, Mallinger LN, Arkee T, Schmidt ME, Bohan D, Brunton B, White JM, Varga SM, Butler NS, Bishop GA, Maury W. J Leukoc Biol. 2020 May 22. doi: 10.1002/JLB.4HI0420-285RR. [Epub ahead of print].

Nicotinamide Riboside Relieves Paclitaxel-Induced Peripheral Neuropathy and Enhances Suppression of Tumor Growth in Tumor-Bearing Rats. Hamity MV, White SR, Blum C, Gibson-Corley KN, Hammond DL. Pain. 2020 May 15. doi: 10.1097/j.pain.0000000000001924. [Epub ahead of print].

Week of May 19, 2020
Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma. Oishi N, Hundal T, Phillips JL, Dasari S, Hu G, Viswanatha DS, He R, Mai M, Jacobs HK, Ahmed NH, Syrbu SI, Salama Y, Chapman JR, Vega F, Sidhu J, Bennani NN, Epstein AL, Medeiros LJ, Clemens MW, Miranda RN, Feldman AL. Haematologica. 2020 May 15. pii: haematol.2019.245860. doi: 10.3324/haematol.2019.245860. [Epub ahead of print].

Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice. Chu Y, Lan RS, Huang R, Feng H, Kumar R, Dayal S, Chan KS, Dai DF. Aging Cell. 2020 May 13. doi: 10.1111/acel.13154. [Epub ahead of print].

Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex. Fiock KL, Smalley ME, Crary JF, Pasca AM, Hefti MM. eNeuro. 2020 May 11. pii: ENEURO.0058-20.2020. doi: 10.1523/ENEURO.0058-20.2020. [Epub ahead of print].

Week of May 12, 2020
A primer on data visualization in infection prevention and antimicrobial stewardship. Salinas JL, Kritzman J, Kobayashi T, Edmond MB, Ince D, Diekema DJ. Infect Control Hosp Epidemiol. 2020 May 11:1-10. doi: 10.1017/ice.2020.142. [Epub ahead of print].

C3(H2O) prevents rescue of complement-mediated C3 glomerulopathy in Cfh-/- Cfd-/- mice. Zhang Y, Keenan A, Dai DF, May KS, Anderson EE, Lindorfer MA, Henrich JB, Pitcher GR, Taylor RP, Smith RJ. JCI Insight. 2020 May 7;5(9). pii: 135758. doi: 10.1172/jci.insight.135758.

COVID-19 Convalescent Plasma; Phase 2. Knudson CM, Jackson JB. Transfusion. 2020 May 6. doi: 10.1111/trf.15842. [Epub ahead of print] No abstract available.

Week of May 5, 2020
Moving Personal Protective Equipment Into the Community: Face Shields and Containment of COVID-19. Perencevich EN, Diekema DJ, Edmond MB. JAMA. 2020 Apr 29. doi: 10.1001/jama.2020.7477. [Epub ahead of print] No abstract available.

Functional Genomic Screening Independently Identifies CUL3 as a Mediator of Vemurafenib Resistance via Src-Rac1 Signaling Axis. Vanneste M, Feddersen CR, Varzavand A, Zhu EY, Foley T, Zhao L, Holt KH, Milhem M, Piper R, Stipp CS, Dupuy AJ, Henry MD. Front Oncol. 2020 Apr 3;10:442. doi: 10.3389/fonc.2020.00442. eCollection 2020.

CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets. Kohlmeyer JL, Gordon DJ, Tanas MR, Monga V, Dodd RD, Quelle DE. Int J Mol Sci. 2020 Apr 24;21(8). pii: E3018. doi: 10.3390/ijms21083018. Review.

Ectopic Tcf1 expression instills a stem-like program in exhausted CD8+ T cells to enhance viral and tumor immunity. Shan Q, Hu S, Chen X, Danahy DB, Badovinac VP, Zang C, Xue HH. Cell Mol Immunol. 2020 Apr 27. doi: 10.1038/s41423-020-0436-5. [Epub ahead of print].

Up-front Treatment With Romiplostim in Children With Acquired Bone Marrow Failure: A Single Institutional Pediatric Case Series. Al-Huniti A, Rathi N, Modi A, Bhagavathi S, Mitten R, Sharathkumar AA. J Pediatr Hematol Oncol. 2020 Apr 24. doi: 10.1097/MPH.0000000000001810. [Epub ahead of print].

Week of April 28, 2020
Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial. Marquez AM, Morgan RW, Ko T, Landis WP, Hefti MM, Mavroudis CD, McManus MJ, Karlsson M, Starr J, Roberts AL, Lin Y, Nadkarni V, Licht DJ, Berg RA, Sutton RM, Kilbaugh TJ. J Am Heart Assoc. 2020 Apr 23:e015032. doi: 10.1161/JAHA.119.015032. [Epub ahead of print].

Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells. Edwards G, Perkins GA, Kim KY, Kong Y, Lee Y, Choi SH, Liu Y, Skowronska-Krawczyk D, Weinreb RN, Zangwill L, Strack S, Ju WK. Cell Death Dis. 2020 Apr 20;11(4):254. doi: 10.1038/s41419-020-2456-6.

Week of April 21, 2020
Innovative use of animal models to advance scientific research. Meyerholz DK, Beck AP, Singh B. Cell Tissue Res. 2020 Apr 19. doi: 10.1007/s00441-020-03210-z. [Epub ahead of print] No abstract available.

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross. Martin MD, Sompallae R, Winborn CS, Harty JT, Badovinac VP. Cell Rep. 2020 Apr 14;31(2):107508. doi: 10.1016/j.celrep.2020.03.072.

Function and Modulation of Type I Interferons during Respiratory Syncytial Virus Infection. Stephens LM, Varga SM. Vaccines (Basel). 2020 Apr 10;8(2). pii: E177. doi: 10.3390/vaccines8020177. Review.

Week of April 14, 2020
Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. Li K, Li Z, Wohlford-Lenane C, Meyerholz DK, Channappanavar R, An D, Perlman S, McCray PB Jr, He B. mBio. 2020 Apr 7;11(2). pii: e00554-20. doi: 10.1128/mBio.00554-20.

CD20+ cutaneous T-cell lymphoma with phenotypic shift after treatment with rituximab: Case report and review of the literature. Tschetter AJ, Zafar F, Moye MS, Ghahramani GK, Swick BL, Link BK, Liu V. JAAD Case Rep. 2020 Mar 25;6(4):308-310. doi: 10.1016/j.jdcr.2020.01.015. eCollection 2020 Apr. No abstract available.

Data on interference indices in body fluid specimens submitted for clinical laboratory analysis. Eigsti RL, Krasowski MD, Vidholia A, Merrill AE. Data Brief. 2020 Mar 10;30:105408. doi: 10.1016/j.dib.2020.105408. eCollection 2020 Jun.

Week of April 7, 2020
Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE. J Am Heart Assoc. 2020 Apr 7;9(7):e014366. doi: 10.1161/JAHA.119.014366. Epub 2020 Apr 4.

Discrepant Hemophilia A: An Underdiagnosed Disease Entity. Al-Huniti A, Sharathkumar A, Krantz M, Watkinson K, Bhagavathi S. Am J Clin Pathol. 2020 Mar 31. pii: aqaa024. doi: 10.1093/ajcp/aqaa024. [Epub ahead of print].

Beyond Metabolism: The Complex Interplay Between Dietary Phytoestrogens, Gut Bacteria, and Cells of Nervous and Immune Systems. Cady N, Peterson SR, Freedman SN, Mangalam AK. Front Neurol. 2020 Mar 13;11:150. doi: 10.3389/fneur.2020.00150. eCollection 2020. Review.

Methods for in vitro modeling of glioma invasion: Choosing tools to meet the need. Dundar B, Markwell SM, Sharma NV, Olson CL, Mukherjee S, Brat DJ. Glia. 2020 Mar 5. doi: 10.1002/glia.23813. [Epub ahead of print] Review.

Week of March 31, 2020
Response to Ling et al. regarding "An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses". Buettner GR, Spitz DR, Limoli CL. Radiother Oncol. 2020 Mar 25. pii: S0167-8140(20)30109-2. doi: 10.1016/j.radonc.2020.03.001. [Epub ahead of print] No abstract available.

An Algorithmic Immunohistochemical Approach to Define Tumor Type and Assign Site of Origin. Bellizzi AM. Adv Anat Pathol. 2020 Mar 19. doi: 10.1097/PAP.0000000000000256. [Epub ahead of print].

Surgical skills video-based assessment tool for dermatology residents: A prospective pilot study. Chitgopeker P, Sidey K, Aronson A, Chung J, Roth G, Swick B , Johnson-Jahangir H, VanBeek M, Wanat KA, Ferguson N. J Am Acad Dermatol. 2020 Mar 20. pii: S0190-9622(19)32654-4. doi: 10.1016/j.jaad.2019.08.048. [Epub ahead of print] No abstract available.

Week of March 24, 2020
Neuropathology of Congenital Heart Disease in an Inpatient Autopsy Cohort 2000-2017. Rettenmaier LA, Kirby PA, Reinking BE, Viaene AN, Hefti MM. J Am Heart Assoc. 2020 Apr 7;9(7):e013575. doi: 10.1161/JAHA.119.013575. Epub 2020 Mar 23.

Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein. Boyden AW, Brate AA, Karandikar NJ. Sci Rep. 2020 Mar 19;10(1):5011. doi: 10.1038/s41598-020-61928-w.

Longitudinal phenotype development in a minipig model of neurofibromatosis type 1. Uthoff J, Larson J, Sato TS, Hammond E, Schroeder KE, Rohret F, Rogers CS, Quelle DE, Darbro BW, Khanna R, Weimer JM, Meyerholz DK, Sieren JC. Sci Rep. 2020 Mar 19;10(1):5046. doi: 10.1038/s41598-020-61251-4.

Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation. Moose DL, Krog BL, Kim TH, Zhao L, Williams-Perez S, Burke G, Rhodes L, Vanneste M, Breheny P, Milhem M, Stipp CS, Rowat AC, Henry MD. Cell Rep. 2020 Mar 17;30(11):3864-3874.e6. doi: 10.1016/j.celrep.2020.02.080.

Worry and FRET: ROS Production Leads to Fluorochrome Tandem Degradation and impairs Interpretation of Flow Cytometric Results. Jensen IJ, McGonagill PW, Lefebvre MN, Griffith TS, Harty JT, Badovinac VP. Immunity. 2020 Mar 17;52(3):419-421. doi: 10.1016/j.immuni.2020.02.003. No abstract available.

Pure Primary Ovarian Carcinoid Tumor. Halvorson TS, Robinson RA, Samuelson MI. Int J Gynecol Pathol. 2020 Mar 16. doi: 10.1097/PGP.0000000000000675. [Epub ahead of print].

Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or Agouti-related peptide. Sapouckey SA, Morselli LL, Deng G, Patil C, Balapattabi K, Oliveira V, Claflin KE, Gomez J, Pearson NA, Potthoff MJ, Gibson-Corley KN, Sigmund CD, Grobe JL. Am J Physiol Regul Integr Comp Physiol. 2020 Mar 18. doi: 10.1152/ajpregu.00297.2019. [Epub ahead of print].

Persistent chlorotrichosis with chronic sun exposure. Connor CJ, Vidal NY, Liu V. Cutis. 2020 Feb;105(2):E25-E27. No abstract available.

Ceftobiprole Activity against Bacteria from Skin and Skin Structure Infections in the United States from 2016 through 2018. Flamm RK, Duncan LR, Hamed KA, Smart JI, Mendes RE, Pfaller MA. Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02566-19. doi: 10.1128/AAC.02566-19. [Epub ahead of print].

Week of March 17, 2020
Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses. Brate AA, Boyden AW, Itani FR, Pewe LL, Harty JT, Karandikar NJ. J Transl Autoimmun. 2019 Dec;2. pii: 100010. doi: 10.1016/j.jtauto.2019.100010.

Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme. Jong CJ, Merrill RA, Wilkerson EM, Herring LE, Graves LM, Strack S. J Biol Chem. 2020 Mar 10. pii: jbc.RA119.011270. doi: 10.1074/jbc.RA119.011270. [Epub ahead of print].

Pathologic Considerations in Gastroenteropancreatic Neuroendocrine Tumors. Bellizzi AM. Surg Oncol Clin N Am. 2020 Apr;29(2):185-208. doi: 10.1016/j.soc.2019.11.003. Review.

Week of March 10, 2020
Deletion of a neuronal Drp1 activator protects against cerebral ischemia. Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. J Neurosci. 2020 Mar 3. pii: JN-RM-1926-19. doi: 10.1523/JNEUROSCI.1926-19.2020. [Epub ahead of print].

A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma. Baranov E, McBride MJ, Bellizzi AM, Ligon AH, Fletcher CDM, Kadoch C, Hornick JL. Am J Surg Pathol. 2020 Mar 3. doi: 10.1097/PAS.0000000000001447. [Epub ahead of print].

A randomized control trial evaluating efficacy of antimicrobial impregnated hospital privacy curtains in an intensive care setting. Wilson G, Jackson V, Boyken L, Puig-Asensio M, Marra AR, Perencevich E, Schweizer ML, Diekema D, Breheny P, Petersen C. Am J Infect Control. 2020 Mar 2. pii: S0196-6553(20)30003-1. doi: 10.1016/j.ajic.2019.12.024. [Epub ahead of print].

Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation. Skurski J, Penniman CM, Geesala R, Dixit G, Pulipati P, Bhardwaj G, Meyerholz DK, Issuree PD, O'Neill BT, Maretzky T. Metabolism. 2020 Mar 2:154194. doi: 10.1016/j.metabol.2020.154194. [Epub ahead of print].

Evolving challenges to model human diseases for translational research. Beck AP, Meyerholz DK. Cell Tissue Res. 2020 Mar 4. doi: 10.1007/s00441-019-03134-3. [Epub ahead of print] Review.

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers into breast cancer clinical trials and daily practice. Gonzalez-Ericsson PI, Stovgaard ES, Sua LF, Reisenbichler E, Kos Z, Carter JM, Michiels S, Le Quesne J, Nielsen TO, Laenkholm AV, Fox SB, Adam J, Bartlett JM, Rimm DL, Quinn C, Peeters D, Dieci MV, Vincent-Salomon A, Cree I, Hida AI, Balko JM, Haynes HR, Frahm I, Acosta-Haab G, Balancin M, Bellolio E, Yang W, Kirtani P, Sugie T, Ehinger A, Castaneda CA, Kok M, McArthur H, Siziopikou K, Badve S, Fineberg S, Gown A, Viale G, Schnitt SJ, Pruneri G, Penault-Llorca F, Hewitt S, Thompson EA, Allison KH, Symmans WF, Bellizzi AM, Brogi E, Moore DA, Larsimont D, Dillon DA, Lazar A, Lien H, Goetz MP, Broeckx G, El Bairi K, Harbeck N, Cimino-Mathews A, Sotiriou C, Adams S, Liu SW, Loibl S, Chen IC, Lakhani SR, Juco JW, Denkert C, Blackley EF, Demaria S, Leon-Ferre R, Gluz O, Zardavas D, Emancipator K, Ely S, Loi S, Salgado R, Sanders M; International Immuno-Oncology Biomarker Working Group. J Pathol. 2020 Mar 4. doi: 10.1002/path.5406. [Epub ahead of print] Review.

Methemoglobinemia due to dietary nitrate. Shrock DL, Krasowski MD. Toxicology Cases for the Clinical and Forensic Laboratory. Chapter 23.6. Philadelphia: Elsevier, 2020.

Week of March 3, 2020
In Vivo Testing of a Prototype Intradural Spinal Cord Stimulator in a Porcine Model. Holland MT, Seaman SC, Woodroffe RW, Fredericks DC, Kovach CK, Gibson-Corley KN, Gillies GT, Howard MA 3rd. World Neurosurg. 2020 Feb 26. pii: S1878-8750(20)30375-2. doi: 10.1016/j.wneu.2020.02.100. [Epub ahead of print].

Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012-2017). Pfaller MA, Carvalhaes CG, Smith CJ, Diekema DJ, Castanheira M. Diagn Microbiol Infect Dis. 2020 Feb 13:115016. doi: 10.1016/j.diagmicrobio.2020.115016. [Epub ahead of print].

Epstein-Barr virus infection status among first year undergraduate university students. Choi A, Marcus K, Pohl D, Eyck PT, Balfour H Jr, Jackson JB. J Am Coll Health. 2020 Feb 26:1-4. doi: 10.1080/07448481.2020.1726927. [Epub ahead of print].

Review of interference indices in body fluid specimens submitted for clinical chemistry analyses. Eigsti RL, Krasowski MD, Vidholia A, Merrill AE. Pract Lab Med. 2020 Feb 8;19:e00155. doi: 10.1016/j.plabm.2020.e00155. eCollection 2020 Mar.

Toxicity assessment of metal oxide nanomaterials using in vitro screening and murine acute inhalation studies. Areecheewakul S, Adamcakova-Dodd A, Givens BE, Steines BR, Wang Y, Meyerholz DK, Parizek NJ, Altmaier R, Haque E, O’Shaughnessy PT, Salem AK, Thorne PS. NANOIMPACT(2020), https://doi.org/10.1016/j.impact.2020.100214.

Week of February 25, 2020
RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors. Kohlmeyer JL, Kaemmer CA, Pulliam C, Maharjan CK, Moreno Samayoa A, Major HJ, Cornick KE, Knepper-Adrian V, Khanna R, Sieren JC, Leidinger M, Meyerholz DK, Zamba KD, Weimer J, Dodd RD, Darbro B, Tanas MR, Quelle DE. Clin Cancer Res. 2020 Feb 21. pii: clincanres.2706.2019. doi: 10.1158/1078-0432.CCR-19-2706. [Epub ahead of print].

Cell cycle progression score has potential prognostic value for stage T1 renal cell carcinomas. West JM, Ma D, Mott SL, Brown JA. Urol Oncol. 2020 Feb 18. pii: S1078-1439(19)30526-5. doi: 10.1016/j.urolonc.2019.12.025. [Epub ahead of print].

In vitro activity of isavuconazole versus opportunistic filamentous fungal pathogens from the SENTRY Antifungal Surveillance Program, 2017-2018. Messer SA, Carvalhaes CG, Castanheira M, Pfaller MA. Diagn Microbiol Infect Dis. 2020 Jan 29:115007. doi: 10.1016/j.diagmicrobio.2020.115007. [Epub ahead of print].

Validating indicators of CNS disorders in a swine model of neurological disease. Swier VJ, White KA, Meyerholz DK, Chefdeville A, Khanna R, Sieren JC, Quelle DE, Weimer JM. PLoS One. 2020 Feb 19;15(2):e0228222. doi: 10.1371/journal.pone.0228222. eCollection 2020.

Surveillance of omadacycline activity tested against clinical isolates from the United States and Europe: Report from the SENTRY Antimicrobial Surveillance Program, 2016-2018. Pfaller MA, Huband MD, Shortridge D, Flamm RK. Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.02488-19. doi: 10.1128/AAC.02488-19. [Epub ahead of print].

In vitro activity of KBP-7072, a novel third-generation tetracycline, against 531 recent geographically diverse and molecularly characterized Acinetobacter baumannii species complex isolates. Huband MD, Mendes RE, Pfaller MA, Lindley JM, Strand GJ, Benn VJ, Zhang J, Li L, Zhang M, Tan X, Liu Q, Flamm RK. Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.02375-19. doi: 10.1128/AAC.02375-19. [Epub ahead of print].

Q&A Column: HER2 testing in colon and other non-breast/non-gastroesophageal adenocarcinomas. Bellizzi AM. CAP Today. 2020 Feb;34(2):64-7.

Unsuspected Cirrhosis-Like Subtype of Hepatocellular Carcinoma in Explanted Liver. Gosse MD, Appelman, HD. AJSP: Reviews & Reports: January/February 2020 - Volume 25 - Issue 1 - p 45-47. doi: 10.1097/PCR.0000000000000351.

Week of February 18, 2020
Data on the relationship between acetone, ethylene glycol, isopropanol, methanol, and propylene glycol serum/plasma concentrations and osmolal gaps in patients at an academic medical center. Greene HR, Krasowski MD. Data Brief. 2020 Jan 27;29:105189. doi: 10.1016/j.dib.2020.105189. eCollection 2020 Apr.

Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases. Alpert L, Al-Sabti R, Graham RP, Pai RK, Gonzalez RS, Zhang X, Smith V, Wang HL, Westbrook L, Goldblum JR, Bakhshwin A, Shetty S, Klimstra DS, Shia J, Askan G, Robert ME, Thomas C, Frankel WL, Alsomali M, Hagen C, Mostafa ME, Feely MM, Assarzadegan N, Misdraji J, Shih AR, Agostini-Vulaj D, Meis JM, Tang S, Chatterjee D, Kang LI, Hart J, Lee SM, Smith T, Yantiss RK, Hissong EM, Gao ZH, Wu J, Resnick MB, Wu EY, Pai RK, Zhao L, Doyle LA, Chopra S, Panarelli NC, Hu S, Longacre TA, Raghavan SS, Lauwers GY, Ghayouri M, Cooper HS, Nagarathinam R, Bellizzi AM, Kakar S, Hosseini M, Rong J, Greenson JK, Lamps LW, Dong Z, Bronner MP. Mod Pathol. 2020 Feb 12. doi: 10.1038/s41379-020-0492-5. [Epub ahead of print].

Cutting Edge: Antitumor Immunity by Pathogen-Specific CD8 T Cells in the Absence of Cognate Antigen Recognition. Danahy DB, Berton RR, Badovinac VP. J Immunol. 2020 Feb 12. pii: ji1901172. doi: 10.4049/jimmunol.1901172. [Epub ahead of print].

Balancing in a black box: Potential immunomodulatory roles for TGF-β signaling during blood-stage malaria. Drewry LL, Harty JT. Virulence. 2020 Dec;11(1):159-169. doi: 10.1080/21505594.2020.1726569.

A novel noncoding FKRP mutation in early onset limb-girdle muscular dystrophy. Saylam E, Moore SA, Aravindhan A, Marton H, Nagy PL, Gokden M, Cox MO, Stefans V, Veerapandiyan A. Neurol Genet. 2019 Dec 26;6(1):e388. doi: 10.1212/NXG.0000000000000388. eCollection 2020 Feb. No abstract available.

Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Kluz PN, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, Kim MC, Wang L, Zhang Y, Li W, Stipp C, Gibson-Corley KN, Zhao C, Qi HH, Bellizzi A, Tao AW, Sugg S, Weigel RJ, Zhou D, Shen X, Zhang W. Oncogene. 2020 Feb 10. doi: 10.1038/s41388-020-1203-x. [Epub ahead of print].

Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacological Ascorbate-Induced Cytotoxicity. Gibson AR, O'Leary BR, Du J, Sarsour EH, Kalen AL, Wagner BA, Stolwijk JM, Falls-Hubert KC, Alexander MS, Carroll RS, Spitz DR, Buettner GR, Goswami PC, Cullen JJ. Cancer Res. 2020 Feb 10. pii: canres.3094.2019. doi: 10.1158/0008-5472.CAN-19-3094. [Epub ahead of print].

TRAF2 Ser-11 phosphorylation promotes cytosolic translocation of the CD40 complex to regulate downstream signaling pathways. Workman LM, Zhang L, Fan Y, Zhang W, Habelhah H. Mol Cell Biol. 2020 Feb 10. pii: MCB.00429-19. doi: 10.1128/MCB.00429-19. [Epub ahead of print].

Week of February 11, 2020
Combination therapy with radiation and PARP inhibition enhances responsiveness to anti-PD-1 therapy in colorectal tumor models. Seyedin SN, Hasibuzzaman MM, Pham V, Petronek MS, Callaghan C, Kalen AL, Mapuskar KA, Mott SL, Spitz DR, Allen BG, Caster JM.nt J Radiat Oncol Biol Phys. 2020 Feb 6. pii: S0360-3016(20)30156-5. doi: 10.1016/j.ijrobp.2020.01.030. [Epub ahead of print].

Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Falls-Hubert KC, Butler AL, Gui K, Anderson M, Li M, Stolwijk JM, Rodman SN 3rd, Solst SR, Tomanek-Chalkley A, Searby CC, Sheffield VC, Sandfort V, Schmidt H, McCormick M, Wels BR, Allen BG, Buettner GR, Schultz MK, Spitz DR. Free Radic Biol Med. 2020 Feb 4. pii: S0891-5849(19)32348-2. doi: 10.1016/j.freeradbiomed.2020.01.186. [Epub ahead of print].

Machine Learning Takes Laboratory Automation to the Next Level. Ford BA, McElvania E. J Clin Microbiol. 2020 Feb 5. pii: JCM.00012-20. doi: 10.1128/JCM.00012-20. [Epub ahead of print].

Modified EUS Needle to Obtain Histological Core Tissue Samples: A Retrospective Analysis. Ashat M, Soota K, Klair JS, Gupta S, Jensen C, Murali AR, Jesudoss R, El-Abiad R, Gerke H. Clin Endosc. 2020 Feb 5. doi: 10.5946/ce.2019.108. [Epub ahead of print].

Activity of a Long-Acting Echinocandin, Rezafungin, and Comparator Antifungal Agents Tested against Contemporary Invasive Fungal Isolates: SENTRY Program 2016-2018. Pfaller MA, Carvalhaes C, Messer SA, Rhomberg PR, Castanheira M. Antimicrob Agents Chemother. 2020 Feb 3. pii: AAC.00099-20. doi: 10.1128/AAC.00099-20. [Epub ahead of print].

Academic E-Mail Overload and the Burden of "Academic Spam". Wood KE, Krasowski MD. Acad Pathol . 2020 Jan 21;7:2374289519898858. doi: 10.1177/2374289519898858. eCollection 2020 Jan-Dec. Review.

The Interplay Between the DNA Damage Response, RNA Processing and Extracellular Vesicles. Meng X, Yang S, Camp VJA. Front Oncol. 2020 Jan 17;9:1538. doi: 10.3389/fonc.2019.01538. eCollection 2019. Review.

Body Mass Index of Freshman University Students. Marcus KS, Choi AB, Pohl DS, Ten Eyck PP, Jackson JB. J Obesity Med Complications. 2020 Jan;1(1):103.

Week of February 4, 2020
Bioaerosols generated from toilet flushing in rooms of patients with Clostridioides difficile infection. Wilson GM, Jackson VB, Boyken LD, Schweizer ML, Diekema DJ, Petersen CA, Breheny PJ, Nonnenmann MW, Perencevich EN; CDC Prevention Epicenter Program. Infect Control Hosp Epidemiol. 2020 Jan 31:1-5. doi: 10.1017/ice.2020.11. [Epub ahead of print].

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia. Tang J, Tu S, Lin G, Guo H, Yan C, Liu Q, Huang L, Tang N, Xiao Y, Pope RM, Rajaram MVS, Amer AO, Ahmer BM, Gunn JS, Wozniak DJ, Tao L, Coppola V, Zhang L, Langdon WY, Torrelles JB, Lipkowitz S, Zhang J. J Exp Med. 2020 Apr 6;217(4). pii: e20182091. doi: 10.1084/jem.20182091.

Correlation between Broth Microdilution and Disk Diffusion Results when Testing Ceftazidime-Avibactam against a Challenge Collection of Enterobacterales: Results from a Multi-Laboratory Study. Sader HS, Rhomberg PR, Chandrasekaran S, Trejo M, Fedler KA, Boyken LD, Diekema DJ. J Clin Microbiol. 2020 Jan 29. pii: JCM.01757-19. doi: 10.1128/JCM.01757-19. [Epub ahead of print].

Anti-Brush Border Antibody Associated Renal Disease (ABBA). Campbell RE, Uhlenhopp D, Shaw M, Dai DF, Sekar A. QJM. 2020 Jan 29. pii: hcaa015. doi: 10.1093/qjmed/hcaa015. [Epub ahead of print] No abstract available.

A-Kinase Anchoring Protein 1: Emerging Roles in Regulating Mitochondrial Form and Function in Health and Disease. Liu Y, Merrill RA, Strack S. Cells. 2020 Jan 26;9(2). pii: E298. doi: 10.3390/cells9020298. Review.

Survival after reoperation for recurrent glioblastoma. Woodroffe RW, Zanaty M, Soni N, Mott SL, Helland LC, Pasha A, Maley J, Dhungana N, Jones KA, Monga V, Greenlee JDW. J Clin Neurosci. 2020 Jan 24. pii: S0967-5868(19)31151-8. doi: 10.1016/j.jocn.2020.01.009. [Epub ahead of print].

Week of January 28, 2020
Educational Case: Ethylene Glycol Poisoning. Krasowski MD. Acad Pathol. 2020 Jan 14;7:2374289519900330. doi: 10.1177/2374289519900330. eCollection 2020 Jan-Dec.

False positive testing for sickle hemoglobin in a blood donor with mild erythrocytosis and hemoglobin Geldrop St. Anna. Dunseth CD, Schlueter AJ, Knudson CM. Transfus Apher Sci. 2020 Jan 9:102724. doi: 10.1016/j.transci.2020.102724. [Epub ahead of print].

Week of January 21, 2020
Paraneoplastic leukemoid reactions induced by cytokine-secreting tumours. Abukhiran IA, Jasser J, Syrbu S. J Clin Pathol. 2020 Jan 15. pii: jclinpath-2019-206340. doi: 10.1136/jclinpath-2019-206340. [Epub ahead of print] Review.

Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors. Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, O'Dorisio TM, Howe JR. Clin Cancer Res. 2020 Jan 14. pii: clincanres.2884.2019. doi: 10.1158/1078-0432.CCR-19-2884. [Epub ahead of print].

MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity. Dhanasekaran R, Baylot V, Kim M, Kuruvilla S, Bellovin DI, Adeniji N, Rajan Kd A, Lai I, Gabay M, Tong L, Krishnan M, Park J, Hu T, Barbhuiya MA, Gentles AJ, Kannan K, Tran PT, Felsher DW. Elife. 2020 Jan 14;9. pii: e50731. doi: 10.7554/eLife.50731.

Week of January 14, 2020

Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis. Marra AR, Perencevich EN, Nelson RE, Samore M, Khader K, Chiang HY, Chorazy ML, Herwaldt LA, Diekema DJ, Kuxhausen MF, Blevins A, Ward MA, McDanel JS, Nair R, Balkenende E, Schweizer ML. JAMA Netw Open. 2020 Jan 3;3(1):e1917597. doi: 10.1001/jamanetworkopen.2019.17597.

ABO-incompatible platelets are associated with increased transfusion reaction rates. Malvik N, Leon J, Schlueter AJ, Wu C, Knudson CM. Transfusion. 2020 Jan 8. doi: 10.1111/trf.15655. [Epub ahead of print].

Correlation of osmolal gap with measured concentrations of acetone, ethylene glycol, isopropanol, methanol, and propylene glycol in patients at an academic medical center. Greene HR, Krasowski MD. Toxicol Rep. 2019 Dec 23;7:81-88. doi: 10.1016/j.toxrep.2019.12.005. eCollection 2020.

Krasowski MD, Snozek CLH. Chapter 19: Club Drugs. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, Snozek CLH, Melanson SEF. Chapter 21: Amphetamines. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, Snozek CLH, Melanson SEF. Chapter 22: Barbiturates. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Snozek CLH, Krasowski MD, Melanson SEF. Chapter 23: Benzodiazepines. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, McMillin GA. Chapter 24: Opioids I: Opiates and Semisynthetic Opioids. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Week of January 7, 2020
Mantle Cell Lymphoma Involving Major and Minor Salivary Glands With Parotid Sparing. View full article in JAMA Otolaryngology Head & Neck Surgery. Abukhiran I, Jasser J, Hoffman HT, Syrbu S. JAMA Otolaryngol Head Neck Surg. 2020 Jan 2. doi: 10.1001/jamaoto.2019.4116. [Epub ahead of print] No abstract available.

Week of December 31, 2019
Multiple facial papules. View full article in Cutis. Holt MH, Liu V. Cutis. 2019 Nov;104(5):E17-E19. No abstract available.

Utility of CD64 Expression on Neutrophils as a Marker to Differentiate Infectious versus Noninfectious Disease Flares in Autoimmune Disorders. Mangalam AK, Yadav R. Indian J Rheumatol. 2019 Mar;14(1):9-11. doi: 10.4103/0973-3698.254192. Epub 2019 Mar 14. No abstract available.

Histopathologic Evaluation and Scoring of Viral Lung Infection. Meyerholz DK, Beck AP. Methods Mol Biol. 2020;2099:205-220. doi: 10.1007/978-1-0716-0211-9_16.

Week of December 24, 2019
Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Hypertension. 2019 Dec 23:HYPERTENSIONAHA11914056. doi: 10.1161/HYPERTENSIONAHA.119.14056. [Epub ahead of print].

Long-term follow-up of post-cardiac surgery Mycobacterium chimaera infections: A 5-center case series. Julian KG, Crook T, Curley E, Appenheimer AB, Paules CI, Hasse B, Diekema DJ, Daley CL, de Sanctis J, Hellinger WC, Levin A, McSherry G, Freer C, Whitener CJ. J Infect. 2019 Dec 18. pii: S0163-4453(19)30379-2. doi: 10.1016/j.jinf.2019.12.007. [Epub ahead of print].

Alpha-dystroglycan staining pattern and mortality in patients undergoing radical prostatectomy with lymph node positive prostate cancer. Alzubaidi AN, Nepple KG, Vollstedt A, Dahmoush L, Ma D, Henry MD, Brown JA. Can J Urol. 2019 Dec;26(6):10054-10060.

Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can Brown do for you? Bellizzi AM. Hum Pathol. 2019 Dec 16. pii: S0046-8177(19)30229-1. doi: 10.1016/j.humpath.2019.12.002. [Epub ahead of print].

Dermatofibrosarcoma protuberans - the use of neoadjuvant imatinib for treatment of an uncommon breast malignancy: a case report. McGee MW, Boukhar SA, Monga V, Weigel R, Phadke SD. J Med Case Rep. 2019 Dec 19;13(1):374. doi: 10.1186/s13256-019-2316-0.

Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells. Earle AJ, Kirby TJ, Fedorchak GR, Isermann P, Patel J, Iruvanti S, Moore SA, Bonne G, Wallrath LL, Lammerding J. Nat Mater. 2019 Dec 16. doi: 10.1038/s41563-019-0563-5. [Epub ahead of print].

Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection. Schmidt ME, Meyerholz DK, Varga SM. Mucosal Immunol. 2019 Dec 16. doi: 10.1038/s41385-019-0243-4. [Epub ahead of print].

Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system. Shahi SK, Freedman SN, Dahl RA, Karandikar NJ, Mangalam AK. Sci Rep. 2019 Dec 16;9(1):19194. doi: 10.1038/s41598-019-55713-7.

You Shall Not Pass: Memory CD8 T Cells in Liver-Stage Malaria. Lefebvre MN, Harty JT. Trends Parasitol. 2019 Dec 13. pii: S1471-4922(19)30278-8. doi: 10.1016/j.pt.2019.11.004. [Epub ahead of print] Review.

Identification of Novel Respiratory Syncytial Virus CD4+ and CD8+ T Cell Epitopes in C57BL/6 Mice. Schmidt ME, Varga SM. Immunohorizons. 2019 Jan 14;3(1):1-12. doi: 10.4049/immunohorizons.1800056.

Week of December 17, 2019
Primary ductal adenocarcinoma of the lacrimal gland: A review and report of five cases. See TRO, Stålhammar G, Tang T, Manusow JS, Jordan DR, Nerad JA, Kersten RC, Yonkers M, Syed NA, Brownstein S, Grossniklaus HE. Surv Ophthalmol. 2019 Dec 11. pii: S0039-6257(19)30289-9. doi: 10.1016/j.survophthal.2019.11.002. [Epub ahead of print] Review.

Vancomycin-induced linear Immunoglobulin A bullous dermatosis. Phyu H, Kobayashi T, Rastogi P, Cho C. BMJ Case Rep. 2019 Dec 9;12(12). pii: e233281. doi: 10.1136/bcr-2019-233281. No abstract available.

Week of December 10, 2019
Educational Case: Hemolysis and Lipemia Interference With Laboratory Testing. Krasowski MD. Acad Pathol. 2019 Nov 22;6:2374289519888754. doi: 10.1177/2374289519888754. eCollection 2019 Jan-Dec.

Data on hydroxychloroquine interference with urine laboratory testing. Kingery JM, Radke JB, Maakestad J, Krasowski MD. Data Brief. 2019 Nov 8;27:104781. doi: 10.1016/j.dib.2019.104781. eCollection 2019 Dec.

Phacomatosis pigmentokeratotica without extracutaneous abnormalities: 12-year follow-up. Hannah CE, Keller JR, Noe MH, Gordon JRS, Fridlington EK, Ceilley RI, Liu V. JAAD Case Rep. 2019 Nov 21;5(12):1055-1057. doi: 10.1016/j.jdcr.2019.07.031. eCollection 2019 Dec. No abstract available.

MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, Li L, Thiel KW, Zhang J, Dai D, Salem AK, Leslie KK, Meng X. Gynecol Oncol. 2019 Nov;155(2):349-358. doi: 10.1016/j.ygyno.2019.08.014. Epub 2019 Aug 30.

Week of December 3, 2019
American registry of pathology expert opinions: Evaluation of poorly differentiated malignant neoplasms on limited samples - Gastrointestinal mucosal biopsies. Bellizzi AM, Montgomery EA, Hornick JL. Ann Diagn Pathol. 2019 Nov 15;44:151419. doi: 10.1016/j.anndiagpath.2019.151419. [Epub ahead of print] Review.

Periocular Sebaceous Carcinoma Masquerading as an Intratarsal Cyst. Radmall BR, Sampson AD, Syed NA, Ko AC. Ophthalmic Plast Reconstr Surg. 2019 Nov 21. doi: 10.1097/IOP.0000000000001505. [Epub ahead of print] No abstract available.

Week of November 26, 2019
Prospects for Delaying Aging. Jackson B, Noble P. Iowa Medicine Fall 2019.

Week of November 19, 2019
Contribution of alternative splicing to breast cancer metastasis. Meng X, Yang S, Zhang J, Yu H. J Cancer Metastasis Treat. 2019;5. pii: 21. doi: 10.20517/2394-4722.2018.96. Epub 2019 Mar 22.

L-carnitine and Vitamin B Complex for PEG-L-asparaginase-Induced Hepatotoxicity. Arora S, Klair J, Bellizzi AM, Tanaka T. ACG Case Rep J. 2019 Aug 28;6(8):e00194. doi: 10.14309/crj.0000000000000194. eCollection 2019 Aug.

Contamination of healthcare workers' hands with E. coli and Klebsiella species after routine patient care: a prospective observational study. Puig-Asensio M, Diekema DJ, Boyken L, Clore GS, Salinas JL, Perencevich EN. Clin Microbiol Infect. 2019 Nov 13. pii: S1198-743X(19)30602-0. doi: 10.1016/j.cmi.2019.11.005. [Epub ahead of print].

Investigating the validity of web-enabled mechanistic case diagramming scores to assess students' integration of foundational and clinical sciences. Ferguson KJ, Kreiter CD, Franklin E, Haugen TH, Dee FR. Adv Health Sci Educ Theory Pract. 2019 Nov 13. doi: 10.1007/s10459-019-09944-y. [Epub ahead of print].

International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass. Hasse B, Hannan M, Keller PM, Maurer FP, Sommerstein R, Mertz D, Wagner D, Fernández-Hidalgo N, Nomura J, Manfrin V, Bettex D, Conte AH, Durante-Mangoni E, Hing-Cheung Tang T, Stuart RL, Lundgren J, Gordon S, Jarashow MC, Schreiber PW, Niemann S, Kohl TA, Daley C, Stewardson AJ, Whitener CJ, Perkins K, Plachouras D, Lamagni T, Chand M, Freiberger T, Zweifel S, Sander P, Schulthess B, Scriven J, Sax H, van Ingen J, Mestres CA, Diekema D, Brown-Elliott BA, Wallace RJ Jr, Baddour LM, Miro JM, Hoen B; M. chimaera ISCVID investigators; Infectious Diseases specialists; Hospital epidemiologists; Microbiologists and molecular typing specialists; Cardiac surgeons/ perfusionists/ cardiologists; Ophthalmology; Anaesthesiologists; Public Health. J Hosp Infect. 2019 Nov 9. pii: S0195-6701(19)30444-X. doi: 10.1016/j.jhin.2019.10.009. [Epub ahead of print].

Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections. Zacharias ZR, Legge KL. J Immunol. 2019 Nov 11. pii: ji1900770. doi: 10.4049/jimmunol.1900770. [Epub ahead of print].

IgG4 related disease of the craniovertebral junction. Park BJ, Starks R, Kirby P, Menezes AH, Dlouhy BJ. World Neurosurg. 2019 Nov 8. pii: S1878-8750(19)32833-5. doi: 10.1016/j.wneu.2019.10.195. [Epub ahead of print].

Inhibition of CaMKII in mitochondria preserves endothelial barrier function after irradiation. Roy SJ, Koval OM, Sebag SC, Ait-Aissa K, Allen BG, Spitz DR, Grumbach IM. Free Radic Biol Med. 2019 Nov 8. pii: S0891-5849(19)31518-7. doi: 10.1016/j.freeradbiomed.2019.11.012. [Epub ahead of print].

Week of November 12, 2019
Coactivation of NF-κB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C. Blood. 2019 Oct 11. pii: blood.2019001438. doi: 10.1182/blood.2019001438. [Epub ahead of print].

Alanine Aminotransferase Results Differ by Analyzer Manufacturer in a National Integrated Health Setting, 2012-2017. Beste LA, Icardi M, Hunt CM, Gylys-Colwell I, Lowy E, Taylor L, Morgan TR, Chang MF, Maier MM, Cheung R. Arch Pathol Lab Med. 2019 Nov 7. doi: 10.5858/arpa.2018-0622-OA. [Epub ahead of print].

Week of November 5, 2019
MiR-199a Inhibits Tumor Growth and Attenuates Chemoresistance by Targeting K-RAS via AKT and ERK Signalings. Li W, Wang L, Ji XB, Wang LH, Ge X, Liu WT, Chen L, Zheng Z, Shi ZM, Liu LZ, Lin MC, Chen JY, Jiang BH. Front Oncol. 2019 Oct 15;9:1071. doi: 10.3389/fonc.2019.01071. eCollection 2019.

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing. Shahi SK, Zarei K, Guseva NV, Mangalam AK. J Vis Exp. 2019 Oct 15;(152). doi: 10.3791/59980.

Innate immune signaling contributes to tubular-cell senescence in the Glis2 knockout mouse model of nephronophthisis. Jin H, Zhang Y, Liu D, Wang SS, Ding Q, Rastogi P, Purvis M, Wang A, Elhadi S, Ren C, Cao C, Chai Y, Igarashi P, Jetten AM, Lu D, Attanasio M. Am J Pathol. 2019 Oct 29. pii: S0002-9440(19)30761-8. doi: 10.1016/j.ajpath.2019.09.013. [Epub ahead of print].

Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα. Haushalter KJ, Schilling JM, Song Y, Sastri M, Perkins GA, Strack S, Taylor SS, Patel HH. Am J Physiol Heart Circ Physiol. 2019 Nov 1. doi: 10.1152/ajpheart.00237.2019. [Epub ahead of print].

Diagnostic pitfalls and laboratory test interference after hydroxychloroquine intoxication: A case report. Radke JB, Kingery JM, Maakestad J, Krasowski MD. Toxicol Rep. 2019 Oct 7;6:1040-1046. doi: 10.1016/j.toxrep.2019.10.006. eCollection 2019.

A Comprehensive Update on the Problem of Blood Culture Contamination and a Discussion of Methods for Addressing the Problem. Doern GV, Carroll KC, Diekema DJ, Garey KW, Rupp ME, Weinstein MP, Sexton DJ. Clin Microbiol Rev. 2019 Oct 30;33(1). pii: e00009-19. doi: 10.1128/CMR.00009-19. Print 2019 Dec 18. Review.

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. Krishnamurthy S, Wohlford-Lenane C, Kandimalla S, Sartre G, Meyerholz DK, Théberge V, Hallée S, Duperré AM, Del'Guidice T, Lepetit-Stoffaes JP, Barbeau X, Guay D, McCray PB Jr. Nat Commun. 2019 Oct 28;10(1):4906. doi: 10.1038/s41467-019-12922-y.

Week of October 29, 2019
Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure. Dai DF, Liu Y, Basisty N, Karunadharma P, Dastidar SG, Chiao YA, Chen T, Beyer RP, Chin MT, Maccoss M, La Spada AR, Rabinovitch PS. Geroscience. 2019 Oct 24. doi: 10.1007/s11357-019-00119-6. [Epub ahead of print].

Antimicrobial Activity of Ceftolozane-Tazobactam Tested against Contemporary (2015-2017) P. aeruginosa Isolates from a Global Surveillance Program. Shortridge D, Pfaller MA, Streit JM, Flamm RK. J Glob Antimicrob Resist. 2019 Oct 21. pii: S2213-7165(19)30263-2. doi: 10.1016/j.jgar.2019.10.009. [Epub ahead of print].

Week of October 22, 2019
Kinetics and Phenotype of the CD4 T Cell Response to Influenza Virus Infections. Hornick EE, Zacharias ZR, Legge KL. Front Immunol. 2019 Oct 2;10:2351. doi: 10.3389/fimmu.2019.02351. eCollection 2019.

Week of October 15, 2019
Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury. Harper MM, Woll AW, Evans LP, Delcau M, Akurathi A, Hedberg-Buenz A, Soukup DA, Boehme N, Hefti MM, Dutca LM, Anderson MG, Bassuk AG. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4159-4170. doi: 10.1167/iovs.19-27565.

Educational Case: Regulatory Issues With Laboratory Testing. Krasowski MD. Acad Pathol. 2019 Sep 25;6:2374289519877549. doi: 10.1177/2374289519877549. eCollection 2019 Jan-Dec.

Therapeutic Drug Monitoring: A Concise Guide. 4th edition. London: Academic Press, 2020. Dasgupta A, Krasowski MD.

Week of October 8, 2019
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis. Qiu JG, Wang L, Liu WJ, Wang JF, Zhao EJ, Zhou FM, Ji XB, Wang LH, Xia ZK, Wang W, Lin MC, Liu LZ, Huang YX, Jiang BH. Front Pharmacol. 2019 Sep 11;10:1002. doi: 10.3389/fphar.2019.01002. eCollection 2019.

Week of October 1, 2019
Epidemiology of suicide in an Iowa cohort. Persons JE, Hefti MM, Nashelsky MB. Public Health. 2019 Sep 26;177:128-134. doi: 10.1016/j.puhe.2019.08.005. [Epub ahead of print].

Week of September 24, 2019
Metadherin enhances vulnerability of cancer cells to ferroptosis. Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner BA, Buettner GR, Spitz DR, Leslie KK, Zhang J, Meng X. Cell Death Dis. 2019 Sep 17;10(10):682. doi: 10.1038/s41419-019-1897-2.

MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, Li L, Thiel KW, Zhang J, Dai D, Salem AK, Leslie KK, Meng X. Gynecol Oncol. 2019 Aug 30. pii: S0090-8258(19)31466-0. doi: 10.1016/j.ygyno.2019.08.014. [Epub ahead of print].

Week of September 17, 2019

A robust and economical pulse-chase protocol to measure the turnover of HaloTag fusion proteins. Merrill RA, Song J, Kephart RA, Klomp AJ, Noack CE, Strack S. J Biol Chem. 2019 Sep 11. pii: jbc.RA119.010596. doi: 10.1074/jbc.RA119.010596. [Epub ahead of print].

Tau Phosphorylation and Aggregation in the Developing Human Brain. Hefti MM, Kim S, Bell AJ, Betters RK, Fiock KL, Iida MA, Smalley ME, Farrell K, Fowkes ME, Crary JF. J Neuropathol Exp Neurol. 2019 Jul 23. pii: nlz073. doi: 10.1093/jnen/nlz073. [Epub ahead of print].

Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice. Kim VY, Batty A, Li J, Kirk SG, Crowell SA, Jin Y, Tang J, Zhang J, Rogers LK, Deng HX, Nelin LD, Liu Y. J Immunol. 2019 Sep 9. pii: ji1701686. doi: 10.4049/jimmunol.1701686. [Epub ahead of print].

Week of September 10, 2019
PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1. Qian X, Li X, Shi Z, Xia Y, Cai Q, Xu D, Tan L, Du L, Zheng Y, Zhao D, Zhang C, Lorenzi PL, You Y, Jiang BH, Jiang T, Li H, Lu Z. Mol Cell. 2019 Aug 22. pii: S1097-2765(19)30622-7. doi: 10.1016/j.molcel.2019.08.006. [Epub ahead of print].

Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis. Qian YC, Xie YX, Wang CS, Shi ZM, Jiang CF, Tang YY, Qian X, Wang L, Jiang BH. Asian J Androl. 2019 Sep 6. doi: 10.4103/aja.aja_76_19. [Epub ahead of print].

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB. Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098.

Week of September 3, 2019
Brain death: Radiologic signs of a non-radiologic diagnosis. Gastala J, Fattal D, Kirby PA, Capizzano AA, Sato Y, Moritani T. Clin Neurol Neurosurg. 2019 Aug 12;185:105465. doi: 10.1016/j.clineuro.2019.105465. [Epub ahead of print] Review.

Atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma in patients <40 years: A study of 116 patients. Waters R, Horvai A, Greipp P, John I, Demicco EG, Dickson BC, Tanas MR, Larsen BT, Din NU, Creytens D, Bahrami A, Doyle LA, Jo VY, Al-Ibraheemi A, Thway K, Jenkins S, Siontis B, Folpe A, Fritchie K. Histopathology. 2019 Aug 30. doi: 10.1111/his.13957. [Epub ahead of print].

The prevalence and significance of radiographic incidental findings during initial staging of melanoma: A retrospective study. Stump M, Keller J, Mott SL, Stolmeier D, Milhem M, Liu V. J Eur Acad Dermatol Venereol. 2019 Aug 30. doi: 10.1111/jdv.15912. [Epub ahead of print].

An Investigation of p53 in Skeletal Muscle Aging. Ebert SM, Dierdorff JM, Meyerholz DK, Bullard SA, Al-Zougbi A, DeLau AD, Tomcheck KC, Skopec ZP, Marcotte GR, Bodine SC, Adams CM. J Appl Physiol (1985). 2019 Aug 29. doi: 10.1152/japplphysiol.00363.2019. [Epub ahead of print].

MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement. Donkervoort S, Sabouny R, Yun P, Gauquelin L, Chao KR, Hu Y, Al Khatib I, Töpf A, Mohassel P, Cummings BB, Kaur R, Saade D, Moore SA, Waddell LB, Farrar MA, Goodrich JK, Uapinyoying P, Chan SHS, Javed A, Leach ME, Karachunski P, Dalton J, Medne L, Harper A, Thompson C, Thiffault I, Specht S, Lamont RE, Saunders C, Racher H, Bernier FP, Mowat D, Witting N, Vissing J, Hanson R, Coffman KA, Hainlen M, Parboosingh JS, Carnevale A, Yoon G, Schnur RE; Care4Rare Canada Consortium, Boycott KM, Mah JK, Straub V, Foley AR, Innes AM, Bönnemann CG, Shutt TE. Acta Neuropathol. 2019 Aug 29. doi: 10.1007/s00401-019-02059-z. [Epub ahead of print].

SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway. Sun X, Wang S, Gai J, Guan J, Li J, Li Y, Zhao J, Zhao C, Fu L, Li Q. Front Oncol. 2019 Aug 13;9:754. doi: 10.3389/fonc.2019.00754. eCollection 2019.

Week of August 27, 2019
Pityriasis rubra pilaris-like eruption in the setting of transient acantholytic dermatosis. View full article in JAAD Case Reports. Brown-Joel ZO, Chung J, Stone MS. JAAD Case Rep. 2019 Aug 5;5(8):733-735. doi: 10.1016/j.jdcr.2019.06.025. eCollection 2019 Aug. No abstract available.

Durable Clinical Benefit in Patients with Advanced Cutaneous Melanoma after Discontinuation of Anti-PD-1 Therapies Due to Immune-Related Adverse Events. Swami U, Monga V, Bossler AD, Zakharia Y, Milhem M. J Oncol. 2019 Jul 25;2019:1856594. doi: 10.1155/2019/1856594. eCollection 2019.

In Vitro Activity of Minocycline against U.S. Isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus species complex, Stenotrophomonas maltophilia, and Burkholderia cepacia complex: Results from the SENTRY Antimicrobial Surveillance Program (2014-2018). Flamm RK, Shortridge D, Castanheira M, Sader HS, Pfaller MA. Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.01154-19. doi: 10.1128/AAC.01154-19. [Epub ahead of print].

First-in-human phase 1 clinical trial of pharmacological ascorbate combined with radiation and temozolomide for newly diagnosed glioblastoma. Bodeker KL, Allen BG, Smith MC, Monga V, Sandhu S, Hohl RJ, Carlisle TL, Brown HA, Hollenbeck NJ, Vollstedt S, Greenlee JDW, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg DJ, Wagner BA, Buettner GR, TenNapel MJ, Smith BJ, Spitz DR, Buatti JM. Clin Cancer Res. 2019 Aug 19. pii: clincanres.0594.2019. doi: 10.1158/1078-0432.CCR-19-0594. [Epub ahead of print].

Response to letter regarding "An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses". View full article in Radiotherapy and Oncology. Spitz DR, Buettner GR, Limoli CL. Radiother Oncol. 2019 Aug 16. pii: S0167-8140(19)32999-8. doi: 10.1016/j.radonc.2019.07.009. [Epub ahead of print] No abstract available.

Week of August 20, 2019
Src-dependent DBL family members drive resistance to vemurafenib in human melanoma. Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ. Cancer Res. 2019 Aug 15. pii: canres.0244.2019. doi: 10.1158/0008-5472.CAN-19-0244. [Epub ahead of print].

Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. mSphere. 2019 Aug 14;4(4). pii: e00553-19. doi: 10.1128/mSphere.00553-19.

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Huggins MA, Sjaastad FV, Pierson M, Kucaba TA, Swanson W, Staley C, Weingarden AR, Jensen IJ, Danahy DB, Badovinac VP, Jameson SC, Vezys V, Masopust D, Khoruts A, Griffith TS, Hamilton SE. Cell Rep. 2019 Aug 13;28(7):1729-1743.e5. doi: 10.1016/j.celrep.2019.07.028.

Week of August 13, 2019
Incidence and Survival Among Young Women With Stage I-III Breast Cancer: SEER 2000-2015. Thomas A, Rhoads A, Pinkerton E, Schroeder MC, Conway KM, Hundley WG, McNally LR, Oleson J, Lynch CF, Romitti PA. JNCI Cancer Spectr. 2019 Jun 7;3(3):pkz040. doi: 10.1093/jncics/pkz040. eCollection 2019 Sep.

Week of August 6, 2019
t(15; 17) associated with primary myelofibrosis: a case report of an unusual clinical presentation and diagnostic dilemma. Nadiminti K, Silverman M, Bhagavathi S, Vikas P. Onco Targets Ther. 2019 Jul 11;12:5449-5455. doi: 10.2147/OTT.S208290. eCollection 2019.

Adverse Effects Profile of Dicycloplatin (DCP) Offers Chemotherapeutic Advantage Over Cisplatin and Carboplatin. Yu JJ, Hogan T, Morley C, Crigger C, Jiao S, Williams DJ, Salkini MW, Yang X, Liang X, Yan B, Cecil C, Winn AC, Zheng J, Guo YI, Jiang BH, Washington IM. Anticancer Res. 2019 Aug;39(8):4455-4462. doi: 10.21873/anticanres.13618.

Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism. Petronek MS, Spitz DR, Buettner GR, Allen BG. Cancers (Basel). 2019 Jul 30;11(8). pii: E1077. doi: 10.3390/cancers11081077. Review.

Week of July 30, 2019
Identification of Novel Respiratory Syncytial Virus CD4+ and CD8+ T Cell Epitopes in C57BL/6 Mice. Schmidt ME, Varga SM. Immunohorizons. 2019 Jan 14;3(1):1-12. doi: 10.4049/immunohorizons.1800056.

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB Jr, Meyerholz DK, Perlman S. J Clin Invest. 2019 Jul 29;130. pii: 126363. doi: 10.1172/JCI126363. eCollection 2019 Jul 29.

A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. Espinosa-Cotton M, Fertig EJ, Stabile LP, Gaither-Davis A, Bauman JE, Schmitz S, Gibson-Corley KN, Cheng Y, Jensen IJ, Badovinac VP, Laux D, Simons AL. Biomark Res. 2019 Jul 16;7:14. doi: 10.1186/s40364-019-0164-0. eCollection 2019.

Predictive Markers Require Thorough Analytic Validation. Troxell ML, Fulton RS, Swanson PE, Bellizzi AM, Fitzgibbons PL, Ambaye AB, Haas TS, Goldsmith JD, Loykasek PA, Miller DV, O'Malley D, Qiu J, Salama ME, Schaberg KB, Schwartz RA, Shia J, Summers TA Jr, Wu Y. Arch Pathol Lab Med. 2019 Aug;143(8):907-909. doi: 10.5858/arpa.2019-0112-LE. No abstract available.

Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics. Guimaraes-Young A, Feddersen CR, Dupuy AJ. Front Oncol. 2019 Jul 9;9:611. doi: 10.3389/fonc.2019.00611. eCollection 2019. Review.

SOD1 deficiency: a novel syndrome distinct from amyotrophic lateral sclerosis. Park JH, Elpers C, Reunert J, McCormick ML, Mohr J, Biskup S, Schwartz O, Rust S, Grüneberg M, Seelhöfer A, Schara U, Boltshauser E, Spitz DR, Marquardt T. Brain. 2019 Aug 1;142(8):2230-2237. doi: 10.1093/brain/awz182.

Week of July 23, 2019
An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research. Brayton CF, Boyd KL, Everitt JL, Meyerholz DK, Treuting PM, Bolon B. ILAR J. 2018 Dec 1;59(1):1-3. doi: 10.1093/ilar/ilz008.

Interstitial lung disease associated with anti-PM-Scl antibody: A single center experience. Ussavarungsi K, Nugent K, Gerke AK, Krasowski MD, Tuetken RS, Lenert PS. Autoimmun Rev. 2019 Jul 16:102355. doi: 10.1016/j.autrev.2019.102355. [Epub ahead of print] No abstract available.

Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. Rajan A, Gibson-Corley KN, Choi AB, Ofori-Amanfo GK, Ten Eyck P, Espinosa-Cotton M, Sperry SM, Simons AL. J Oncol. 2019 Jun 19;2019:5859680. doi: 10.1155/2019/5859680. eCollection 2019.

Interpretation and Utility of Drug of Abuse Screening Immunoassays: Insights From Laboratory Drug Testing Proficiency Surveys. Krasowski MD, McMillin GA, Melanson SEF, Dizon A, Magnani B, Snozek CLH. Arch Pathol Lab Med. 2019 Jul 17. doi: 10.5858/arpa.2018-0562-CP. [Epub ahead of print].

Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells. Martin MD, Jensen IJ, Ishizuka AS, Lefebvre M, Shan Q, Xue HH, Harty JT, Seder RA, Badovinac VP. J Clin Invest. 2019 Jun 20;130. pii: 124443. doi: 10.1172/JCI124443.

Week of July 16, 2019
The clinical characteristics of melanoma with BRAF V600R mutation: a case series study. Malkhasyan KA, Rooney SL, Snow AN, Swick BL, Milhem MM, Zakharia Y. Melanoma Res. 2019 Jul 11. doi: 10.1097/CMR.0000000000000630. [Epub ahead of print].

BK virus histopathologic disease severity does not predict allograft outcome in renal transplant recipients. Sanders ML, Swee M, Fraer M, Kuppachi S, Ten Eyck P, Rastogi P. Ann Diagn Pathol. 2019 Jun 27;42:1-6. doi: 10.1016/j.anndiagpath.2019.06.012. [Epub ahead of print].

Magnetic Resonance Imaging characteristics in case of TOR1AIP1 muscular dystrophy. Bhatia A, Mobley BC, Cogan J, Koziura ME, Brokamp E, Phillips J, Newman J; Undiagnosed Diseases Network (UDN), Moore SA, Hamid R; Members of the Undiagnosed Diseases Network. Clin Imaging. 2019 Jun 21;58:108-113. doi: 10.1016/j.clinimag.2019.06.010. [Epub ahead of print].

Unilateral Nasal Mass in a Woman in Her 20s. View full article in JAMA Otolaryngology-Head Neck Surgery. Tasche KK, Samuelson MI, Pagedar NA. JAMA Otolaryngol Head Neck Surg. 2019 Jul 11. doi: 10.1001/jamaoto.2019.1671. [Epub ahead of print] No abstract available.