Recent Publications

Week of February 11, 2020
Combination therapy with radiation and PARP inhibition enhances responsiveness to anti-PD-1 therapy in colorectal tumor models. Seyedin SN, Hasibuzzaman MM, Pham V, Petronek MS, Callaghan C, Kalen AL, Mapuskar KA, Mott SL, Spitz DR, Allen BG, Caster JM.nt J Radiat Oncol Biol Phys. 2020 Feb 6. pii: S0360-3016(20)30156-5. doi: 10.1016/j.ijrobp.2020.01.030. [Epub ahead of print].

Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Falls-Hubert KC, Butler AL, Gui K, Anderson M, Li M, Stolwijk JM, Rodman SN 3rd, Solst SR, Tomanek-Chalkley A, Searby CC, Sheffield VC, Sandfort V, Schmidt H, McCormick M, Wels BR, Allen BG, Buettner GR, Schultz MK, Spitz DR. Free Radic Biol Med. 2020 Feb 4. pii: S0891-5849(19)32348-2. doi: 10.1016/j.freeradbiomed.2020.01.186. [Epub ahead of print].

Machine Learning Takes Laboratory Automation to the Next Level. Ford BA, McElvania E. J Clin Microbiol. 2020 Feb 5. pii: JCM.00012-20. doi: 10.1128/JCM.00012-20. [Epub ahead of print].

Modified EUS Needle to Obtain Histological Core Tissue Samples: A Retrospective Analysis. Ashat M, Soota K, Klair JS, Gupta S, Jensen C, Murali AR, Jesudoss R, El-Abiad R, Gerke H. Clin Endosc. 2020 Feb 5. doi: 10.5946/ce.2019.108. [Epub ahead of print].

Activity of a Long-Acting Echinocandin, Rezafungin, and Comparator Antifungal Agents Tested against Contemporary Invasive Fungal Isolates: SENTRY Program 2016-2018. Pfaller MA, Carvalhaes C, Messer SA, Rhomberg PR, Castanheira M. Antimicrob Agents Chemother. 2020 Feb 3. pii: AAC.00099-20. doi: 10.1128/AAC.00099-20. [Epub ahead of print].

Academic E-Mail Overload and the Burden of "Academic Spam". Wood KE, Krasowski MD. Acad Pathol . 2020 Jan 21;7:2374289519898858. doi: 10.1177/2374289519898858. eCollection 2020 Jan-Dec. Review.

The Interplay Between the DNA Damage Response, RNA Processing and Extracellular Vesicles. Meng X, Yang S, Camp VJA. Front Oncol. 2020 Jan 17;9:1538. doi: 10.3389/fonc.2019.01538. eCollection 2019. Review.

Body Mass Index of Freshman University Students. Marcus KS, Choi AB, Pohl DS, Ten Eyck PP, Jackson JB. J Obesity Med Complications. 2020 Jan;1(1):103.

Week of February 4, 2020
Bioaerosols generated from toilet flushing in rooms of patients with Clostridioides difficile infection. Wilson GM, Jackson VB, Boyken LD, Schweizer ML, Diekema DJ, Petersen CA, Breheny PJ, Nonnenmann MW, Perencevich EN; CDC Prevention Epicenter Program. Infect Control Hosp Epidemiol. 2020 Jan 31:1-5. doi: 10.1017/ice.2020.11. [Epub ahead of print].

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia. Tang J, Tu S, Lin G, Guo H, Yan C, Liu Q, Huang L, Tang N, Xiao Y, Pope RM, Rajaram MVS, Amer AO, Ahmer BM, Gunn JS, Wozniak DJ, Tao L, Coppola V, Zhang L, Langdon WY, Torrelles JB, Lipkowitz S, Zhang J. J Exp Med. 2020 Apr 6;217(4). pii: e20182091. doi: 10.1084/jem.20182091.

Correlation between Broth Microdilution and Disk Diffusion Results when Testing Ceftazidime-Avibactam against a Challenge Collection of Enterobacterales: Results from a Multi-Laboratory Study. Sader HS, Rhomberg PR, Chandrasekaran S, Trejo M, Fedler KA, Boyken LD, Diekema DJ. J Clin Microbiol. 2020 Jan 29. pii: JCM.01757-19. doi: 10.1128/JCM.01757-19. [Epub ahead of print].

Anti-Brush Border Antibody Associated Renal Disease (ABBA). Campbell RE, Uhlenhopp D, Shaw M, Dai DF, Sekar A. QJM. 2020 Jan 29. pii: hcaa015. doi: 10.1093/qjmed/hcaa015. [Epub ahead of print] No abstract available.

A-Kinase Anchoring Protein 1: Emerging Roles in Regulating Mitochondrial Form and Function in Health and Disease. Liu Y, Merrill RA, Strack S. Cells. 2020 Jan 26;9(2). pii: E298. doi: 10.3390/cells9020298. Review.

Survival after reoperation for recurrent glioblastoma. Woodroffe RW, Zanaty M, Soni N, Mott SL, Helland LC, Pasha A, Maley J, Dhungana N, Jones KA, Monga V, Greenlee JDW. J Clin Neurosci. 2020 Jan 24. pii: S0967-5868(19)31151-8. doi: 10.1016/j.jocn.2020.01.009. [Epub ahead of print].

Week of January 28, 2020
Educational Case: Ethylene Glycol Poisoning. Krasowski MD. Acad Pathol. 2020 Jan 14;7:2374289519900330. doi: 10.1177/2374289519900330. eCollection 2020 Jan-Dec.

False positive testing for sickle hemoglobin in a blood donor with mild erythrocytosis and hemoglobin Geldrop St. Anna. Dunseth CD, Schlueter AJ, Knudson CM. Transfus Apher Sci. 2020 Jan 9:102724. doi: 10.1016/j.transci.2020.102724. [Epub ahead of print].

Week of January 21, 2020
Paraneoplastic leukemoid reactions induced by cytokine-secreting tumours. Abukhiran IA, Jasser J, Syrbu S. J Clin Pathol. 2020 Jan 15. pii: jclinpath-2019-206340. doi: 10.1136/jclinpath-2019-206340. [Epub ahead of print] Review.

Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors. Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, O'Dorisio TM, Howe JR. Clin Cancer Res. 2020 Jan 14. pii: clincanres.2884.2019. doi: 10.1158/1078-0432.CCR-19-2884. [Epub ahead of print].

MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity. Dhanasekaran R, Baylot V, Kim M, Kuruvilla S, Bellovin DI, Adeniji N, Rajan Kd A, Lai I, Gabay M, Tong L, Krishnan M, Park J, Hu T, Barbhuiya MA, Gentles AJ, Kannan K, Tran PT, Felsher DW. Elife. 2020 Jan 14;9. pii: e50731. doi: 10.7554/eLife.50731.

Week of January 14, 2020

Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis. Marra AR, Perencevich EN, Nelson RE, Samore M, Khader K, Chiang HY, Chorazy ML, Herwaldt LA, Diekema DJ, Kuxhausen MF, Blevins A, Ward MA, McDanel JS, Nair R, Balkenende E, Schweizer ML. JAMA Netw Open. 2020 Jan 3;3(1):e1917597. doi: 10.1001/jamanetworkopen.2019.17597.

ABO-incompatible platelets are associated with increased transfusion reaction rates. Malvik N, Leon J, Schlueter AJ, Wu C, Knudson CM. Transfusion. 2020 Jan 8. doi: 10.1111/trf.15655. [Epub ahead of print].

Correlation of osmolal gap with measured concentrations of acetone, ethylene glycol, isopropanol, methanol, and propylene glycol in patients at an academic medical center. Greene HR, Krasowski MD. Toxicol Rep. 2019 Dec 23;7:81-88. doi: 10.1016/j.toxrep.2019.12.005. eCollection 2020.

Krasowski MD, Snozek CLH. Chapter 19: Club Drugs. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, Snozek CLH, Melanson SEF. Chapter 21: Amphetamines. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, Snozek CLH, Melanson SEF. Chapter 22: Barbiturates. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Snozek CLH, Krasowski MD, Melanson SEF. Chapter 23: Benzodiazepines. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Krasowski MD, McMillin GA. Chapter 24: Opioids I: Opiates and Semisynthetic Opioids. In: Magnani B et al, eds. Clinical Toxicology Testing: A Guide for Laboratory Professionals. 2nd edition. Northfield (Illinois): College of American Pathologists, 2020.

Week of January 7, 2020
Mantle Cell Lymphoma Involving Major and Minor Salivary Glands With Parotid Sparing. View full article in JAMA Otolaryngology Head & Neck Surgery. Abukhiran I, Jasser J, Hoffman HT, Syrbu S. JAMA Otolaryngol Head Neck Surg. 2020 Jan 2. doi: 10.1001/jamaoto.2019.4116. [Epub ahead of print] No abstract available.

Week of December 31, 2019
Multiple facial papules. View full article in Cutis. Holt MH, Liu V. Cutis. 2019 Nov;104(5):E17-E19. No abstract available.

Utility of CD64 Expression on Neutrophils as a Marker to Differentiate Infectious versus Noninfectious Disease Flares in Autoimmune Disorders. View full article in Indian Journal of Rheumatology. Mangalam AK, Yadav R. Indian J Rheumatol. 2019 Mar;14(1):9-11. doi: 10.4103/0973-3698.254192. Epub 2019 Mar 14. No abstract available.

Histopathologic Evaluation and Scoring of Viral Lung Infection. Meyerholz DK, Beck AP. Methods Mol Biol. 2020;2099:205-220. doi: 10.1007/978-1-0716-0211-9_16.

Week of December 24, 2019
Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Hypertension. 2019 Dec 23:HYPERTENSIONAHA11914056. doi: 10.1161/HYPERTENSIONAHA.119.14056. [Epub ahead of print].

Long-term follow-up of post-cardiac surgery Mycobacterium chimaera infections: A 5-center case series. Julian KG, Crook T, Curley E, Appenheimer AB, Paules CI, Hasse B, Diekema DJ, Daley CL, de Sanctis J, Hellinger WC, Levin A, McSherry G, Freer C, Whitener CJ. J Infect. 2019 Dec 18. pii: S0163-4453(19)30379-2. doi: 10.1016/j.jinf.2019.12.007. [Epub ahead of print].

Alpha-dystroglycan staining pattern and mortality in patients undergoing radical prostatectomy with lymph node positive prostate cancer. Alzubaidi AN, Nepple KG, Vollstedt A, Dahmoush L, Ma D, Henry MD, Brown JA. Can J Urol. 2019 Dec;26(6):10054-10060.

Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can Brown do for you? Bellizzi AM. Hum Pathol. 2019 Dec 16. pii: S0046-8177(19)30229-1. doi: 10.1016/j.humpath.2019.12.002. [Epub ahead of print].

Dermatofibrosarcoma protuberans - the use of neoadjuvant imatinib for treatment of an uncommon breast malignancy: a case report. McGee MW, Boukhar SA, Monga V, Weigel R, Phadke SD. J Med Case Rep. 2019 Dec 19;13(1):374. doi: 10.1186/s13256-019-2316-0.

Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells. Earle AJ, Kirby TJ, Fedorchak GR, Isermann P, Patel J, Iruvanti S, Moore SA, Bonne G, Wallrath LL, Lammerding J. Nat Mater. 2019 Dec 16. doi: 10.1038/s41563-019-0563-5. [Epub ahead of print].

Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection. Schmidt ME, Meyerholz DK, Varga SM. Mucosal Immunol. 2019 Dec 16. doi: 10.1038/s41385-019-0243-4. [Epub ahead of print].

Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system. Shahi SK, Freedman SN, Dahl RA, Karandikar NJ, Mangalam AK. Sci Rep. 2019 Dec 16;9(1):19194. doi: 10.1038/s41598-019-55713-7.

You Shall Not Pass: Memory CD8 T Cells in Liver-Stage Malaria. Lefebvre MN, Harty JT. Trends Parasitol. 2019 Dec 13. pii: S1471-4922(19)30278-8. doi: 10.1016/ [Epub ahead of print] Review.

Identification of Novel Respiratory Syncytial Virus CD4+ and CD8+ T Cell Epitopes in C57BL/6 Mice. Schmidt ME, Varga SM. Immunohorizons. 2019 Jan 14;3(1):1-12. doi: 10.4049/immunohorizons.1800056.

Week of December 17, 2019
Primary ductal adenocarcinoma of the lacrimal gland: A review and report of five cases. See TRO, Stålhammar G, Tang T, Manusow JS, Jordan DR, Nerad JA, Kersten RC, Yonkers M, Syed NA, Brownstein S, Grossniklaus HE. Surv Ophthalmol. 2019 Dec 11. pii: S0039-6257(19)30289-9. doi: 10.1016/j.survophthal.2019.11.002. [Epub ahead of print] Review.

Vancomycin-induced linear Immunoglobulin A bullous dermatosis. Phyu H, Kobayashi T, Rastogi P, Cho C. BMJ Case Rep. 2019 Dec 9;12(12). pii: e233281. doi: 10.1136/bcr-2019-233281. No abstract available.

Week of December 10, 2019
Educational Case: Hemolysis and Lipemia Interference With Laboratory Testing. Krasowski MD. Acad Pathol. 2019 Nov 22;6:2374289519888754. doi: 10.1177/2374289519888754. eCollection 2019 Jan-Dec.

Data on hydroxychloroquine interference with urine laboratory testing. Kingery JM, Radke JB, Maakestad J, Krasowski MD. Data Brief. 2019 Nov 8;27:104781. doi: 10.1016/j.dib.2019.104781. eCollection 2019 Dec.

Phacomatosis pigmentokeratotica without extracutaneous abnormalities: 12-year follow-up. Hannah CE, Keller JR, Noe MH, Gordon JRS, Fridlington EK, Ceilley RI, Liu V. JAAD Case Rep. 2019 Nov 21;5(12):1055-1057. doi: 10.1016/j.jdcr.2019.07.031. eCollection 2019 Dec. No abstract available.

MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, Li L, Thiel KW, Zhang J, Dai D, Salem AK, Leslie KK, Meng X. Gynecol Oncol. 2019 Nov;155(2):349-358. doi: 10.1016/j.ygyno.2019.08.014. Epub 2019 Aug 30.

Week of December 3, 2019
American registry of pathology expert opinions: Evaluation of poorly differentiated malignant neoplasms on limited samples - Gastrointestinal mucosal biopsies. Bellizzi AM, Montgomery EA, Hornick JL. Ann Diagn Pathol. 2019 Nov 15;44:151419. doi: 10.1016/j.anndiagpath.2019.151419. [Epub ahead of print] Review.

Periocular Sebaceous Carcinoma Masquerading as an Intratarsal Cyst. Radmall BR, Sampson AD, Syed NA, Ko AC. Ophthalmic Plast Reconstr Surg. 2019 Nov 21. doi: 10.1097/IOP.0000000000001505. [Epub ahead of print] No abstract available.

Week of November 26, 2019
Prospects for Delaying Aging. Jackson B, Noble P. Iowa Medicine Fall 2019.

Week of November 19, 2019
Contribution of alternative splicing to breast cancer metastasis. Meng X, Yang S, Zhang J, Yu H. J Cancer Metastasis Treat. 2019;5. pii: 21. doi: 10.20517/2394-4722.2018.96. Epub 2019 Mar 22.

L-carnitine and Vitamin B Complex for PEG-L-asparaginase-Induced Hepatotoxicity. Arora S, Klair J, Bellizzi AM, Tanaka T. ACG Case Rep J. 2019 Aug 28;6(8):e00194. doi: 10.14309/crj.0000000000000194. eCollection 2019 Aug.

Contamination of healthcare workers' hands with E. coli and Klebsiella species after routine patient care: a prospective observational study. Puig-Asensio M, Diekema DJ, Boyken L, Clore GS, Salinas JL, Perencevich EN. Clin Microbiol Infect. 2019 Nov 13. pii: S1198-743X(19)30602-0. doi: 10.1016/j.cmi.2019.11.005. [Epub ahead of print].

Investigating the validity of web-enabled mechanistic case diagramming scores to assess students' integration of foundational and clinical sciences. Ferguson KJ, Kreiter CD, Franklin E, Haugen TH, Dee FR. Adv Health Sci Educ Theory Pract. 2019 Nov 13. doi: 10.1007/s10459-019-09944-y. [Epub ahead of print].

International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass. Hasse B, Hannan M, Keller PM, Maurer FP, Sommerstein R, Mertz D, Wagner D, Fernández-Hidalgo N, Nomura J, Manfrin V, Bettex D, Conte AH, Durante-Mangoni E, Hing-Cheung Tang T, Stuart RL, Lundgren J, Gordon S, Jarashow MC, Schreiber PW, Niemann S, Kohl TA, Daley C, Stewardson AJ, Whitener CJ, Perkins K, Plachouras D, Lamagni T, Chand M, Freiberger T, Zweifel S, Sander P, Schulthess B, Scriven J, Sax H, van Ingen J, Mestres CA, Diekema D, Brown-Elliott BA, Wallace RJ Jr, Baddour LM, Miro JM, Hoen B; M. chimaera ISCVID investigators; Infectious Diseases specialists; Hospital epidemiologists; Microbiologists and molecular typing specialists; Cardiac surgeons/ perfusionists/ cardiologists; Ophthalmology; Anaesthesiologists; Public Health. J Hosp Infect. 2019 Nov 9. pii: S0195-6701(19)30444-X. doi: 10.1016/j.jhin.2019.10.009. [Epub ahead of print].

Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections. Zacharias ZR, Legge KL. J Immunol. 2019 Nov 11. pii: ji1900770. doi: 10.4049/jimmunol.1900770. [Epub ahead of print].

IgG4 related disease of the craniovertebral junction. Park BJ, Starks R, Kirby P, Menezes AH, Dlouhy BJ. World Neurosurg. 2019 Nov 8. pii: S1878-8750(19)32833-5. doi: 10.1016/j.wneu.2019.10.195. [Epub ahead of print].

Inhibition of CaMKII in mitochondria preserves endothelial barrier function after irradiation. Roy SJ, Koval OM, Sebag SC, Ait-Aissa K, Allen BG, Spitz DR, Grumbach IM. Free Radic Biol Med. 2019 Nov 8. pii: S0891-5849(19)31518-7. doi: 10.1016/j.freeradbiomed.2019.11.012. [Epub ahead of print].

Week of November 12, 2019
Coactivation of NF-κB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C. Blood. 2019 Oct 11. pii: blood.2019001438. doi: 10.1182/blood.2019001438. [Epub ahead of print].

Alanine Aminotransferase Results Differ by Analyzer Manufacturer in a National Integrated Health Setting, 2012-2017. Beste LA, Icardi M, Hunt CM, Gylys-Colwell I, Lowy E, Taylor L, Morgan TR, Chang MF, Maier MM, Cheung R. Arch Pathol Lab Med. 2019 Nov 7. doi: 10.5858/arpa.2018-0622-OA. [Epub ahead of print].

Week of November 5, 2019
MiR-199a Inhibits Tumor Growth and Attenuates Chemoresistance by Targeting K-RAS via AKT and ERK Signalings. Li W, Wang L, Ji XB, Wang LH, Ge X, Liu WT, Chen L, Zheng Z, Shi ZM, Liu LZ, Lin MC, Chen JY, Jiang BH. Front Oncol. 2019 Oct 15;9:1071. doi: 10.3389/fonc.2019.01071. eCollection 2019.

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing. Shahi SK, Zarei K, Guseva NV, Mangalam AK. J Vis Exp. 2019 Oct 15;(152). doi: 10.3791/59980.

Innate immune signaling contributes to tubular-cell senescence in the Glis2 knockout mouse model of nephronophthisis. Jin H, Zhang Y, Liu D, Wang SS, Ding Q, Rastogi P, Purvis M, Wang A, Elhadi S, Ren C, Cao C, Chai Y, Igarashi P, Jetten AM, Lu D, Attanasio M. Am J Pathol. 2019 Oct 29. pii: S0002-9440(19)30761-8. doi: 10.1016/j.ajpath.2019.09.013. [Epub ahead of print].

Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα. Haushalter KJ, Schilling JM, Song Y, Sastri M, Perkins GA, Strack S, Taylor SS, Patel HH. Am J Physiol Heart Circ Physiol. 2019 Nov 1. doi: 10.1152/ajpheart.00237.2019. [Epub ahead of print].

Diagnostic pitfalls and laboratory test interference after hydroxychloroquine intoxication: A case report. Radke JB, Kingery JM, Maakestad J, Krasowski MD. Toxicol Rep. 2019 Oct 7;6:1040-1046. doi: 10.1016/j.toxrep.2019.10.006. eCollection 2019.

A Comprehensive Update on the Problem of Blood Culture Contamination and a Discussion of Methods for Addressing the Problem. Doern GV, Carroll KC, Diekema DJ, Garey KW, Rupp ME, Weinstein MP, Sexton DJ. Clin Microbiol Rev. 2019 Oct 30;33(1). pii: e00009-19. doi: 10.1128/CMR.00009-19. Print 2019 Dec 18. Review.

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. Krishnamurthy S, Wohlford-Lenane C, Kandimalla S, Sartre G, Meyerholz DK, Théberge V, Hallée S, Duperré AM, Del'Guidice T, Lepetit-Stoffaes JP, Barbeau X, Guay D, McCray PB Jr. Nat Commun. 2019 Oct 28;10(1):4906. doi: 10.1038/s41467-019-12922-y.

Week of October 29, 2019
Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure. Dai DF, Liu Y, Basisty N, Karunadharma P, Dastidar SG, Chiao YA, Chen T, Beyer RP, Chin MT, Maccoss M, La Spada AR, Rabinovitch PS. Geroscience. 2019 Oct 24. doi: 10.1007/s11357-019-00119-6. [Epub ahead of print].

Antimicrobial Activity of Ceftolozane-Tazobactam Tested against Contemporary (2015-2017) P. aeruginosa Isolates from a Global Surveillance Program. Shortridge D, Pfaller MA, Streit JM, Flamm RK. J Glob Antimicrob Resist. 2019 Oct 21. pii: S2213-7165(19)30263-2. doi: 10.1016/j.jgar.2019.10.009. [Epub ahead of print].

Week of October 22, 2019
Kinetics and Phenotype of the CD4 T Cell Response to Influenza Virus Infections. Hornick EE, Zacharias ZR, Legge KL. Front Immunol. 2019 Oct 2;10:2351. doi: 10.3389/fimmu.2019.02351. eCollection 2019.

Week of October 15, 2019
Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury. Harper MM, Woll AW, Evans LP, Delcau M, Akurathi A, Hedberg-Buenz A, Soukup DA, Boehme N, Hefti MM, Dutca LM, Anderson MG, Bassuk AG. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4159-4170. doi: 10.1167/iovs.19-27565.

Educational Case: Regulatory Issues With Laboratory Testing. Krasowski MD. Acad Pathol. 2019 Sep 25;6:2374289519877549. doi: 10.1177/2374289519877549. eCollection 2019 Jan-Dec.

Therapeutic Drug Monitoring: A Concise Guide. 4th edition. London: Academic Press, 2020. Dasgupta A, Krasowski MD.

Week of October 8, 2019
Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis. Qiu JG, Wang L, Liu WJ, Wang JF, Zhao EJ, Zhou FM, Ji XB, Wang LH, Xia ZK, Wang W, Lin MC, Liu LZ, Huang YX, Jiang BH. Front Pharmacol. 2019 Sep 11;10:1002. doi: 10.3389/fphar.2019.01002. eCollection 2019.

Week of October 1, 2019
Epidemiology of suicide in an Iowa cohort. Persons JE, Hefti MM, Nashelsky MB. Public Health. 2019 Sep 26;177:128-134. doi: 10.1016/j.puhe.2019.08.005. [Epub ahead of print].

Week of September 24, 2019
Metadherin enhances vulnerability of cancer cells to ferroptosis. Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner BA, Buettner GR, Spitz DR, Leslie KK, Zhang J, Meng X. Cell Death Dis. 2019 Sep 17;10(10):682. doi: 10.1038/s41419-019-1897-2.

MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy. Bi J, Areecheewakul S, Li Y, Yang S, Zhang Y, Ebeid K, Li L, Thiel KW, Zhang J, Dai D, Salem AK, Leslie KK, Meng X. Gynecol Oncol. 2019 Aug 30. pii: S0090-8258(19)31466-0. doi: 10.1016/j.ygyno.2019.08.014. [Epub ahead of print].

Week of September 17, 2019

A robust and economical pulse-chase protocol to measure the turnover of HaloTag fusion proteins. Merrill RA, Song J, Kephart RA, Klomp AJ, Noack CE, Strack S. J Biol Chem. 2019 Sep 11. pii: jbc.RA119.010596. doi: 10.1074/jbc.RA119.010596. [Epub ahead of print].

Tau Phosphorylation and Aggregation in the Developing Human Brain. Hefti MM, Kim S, Bell AJ, Betters RK, Fiock KL, Iida MA, Smalley ME, Farrell K, Fowkes ME, Crary JF. J Neuropathol Exp Neurol. 2019 Jul 23. pii: nlz073. doi: 10.1093/jnen/nlz073. [Epub ahead of print].

Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice. Kim VY, Batty A, Li J, Kirk SG, Crowell SA, Jin Y, Tang J, Zhang J, Rogers LK, Deng HX, Nelin LD, Liu Y. J Immunol. 2019 Sep 9. pii: ji1701686. doi: 10.4049/jimmunol.1701686. [Epub ahead of print].

Week of September 10, 2019
PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1. Qian X, Li X, Shi Z, Xia Y, Cai Q, Xu D, Tan L, Du L, Zheng Y, Zhao D, Zhang C, Lorenzi PL, You Y, Jiang BH, Jiang T, Li H, Lu Z. Mol Cell. 2019 Aug 22. pii: S1097-2765(19)30622-7. doi: 10.1016/j.molcel.2019.08.006. [Epub ahead of print].

Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis. Qian YC, Xie YX, Wang CS, Shi ZM, Jiang CF, Tang YY, Qian X, Wang L, Jiang BH. Asian J Androl. 2019 Sep 6. doi: 10.4103/aja.aja_76_19. [Epub ahead of print].

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB. Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098.

Week of September 3, 2019
Brain death: Radiologic signs of a non-radiologic diagnosis. Gastala J, Fattal D, Kirby PA, Capizzano AA, Sato Y, Moritani T. Clin Neurol Neurosurg. 2019 Aug 12;185:105465. doi: 10.1016/j.clineuro.2019.105465. [Epub ahead of print] Review.

Atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma in patients <40 years: A study of 116 patients. Waters R, Horvai A, Greipp P, John I, Demicco EG, Dickson BC, Tanas MR, Larsen BT, Din NU, Creytens D, Bahrami A, Doyle LA, Jo VY, Al-Ibraheemi A, Thway K, Jenkins S, Siontis B, Folpe A, Fritchie K. Histopathology. 2019 Aug 30. doi: 10.1111/his.13957. [Epub ahead of print].

The prevalence and significance of radiographic incidental findings during initial staging of melanoma: A retrospective study. Stump M, Keller J, Mott SL, Stolmeier D, Milhem M, Liu V. J Eur Acad Dermatol Venereol. 2019 Aug 30. doi: 10.1111/jdv.15912. [Epub ahead of print].

An Investigation of p53 in Skeletal Muscle Aging. Ebert SM, Dierdorff JM, Meyerholz DK, Bullard SA, Al-Zougbi A, DeLau AD, Tomcheck KC, Skopec ZP, Marcotte GR, Bodine SC, Adams CM. J Appl Physiol (1985). 2019 Aug 29. doi: 10.1152/japplphysiol.00363.2019. [Epub ahead of print].

MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement. Donkervoort S, Sabouny R, Yun P, Gauquelin L, Chao KR, Hu Y, Al Khatib I, Töpf A, Mohassel P, Cummings BB, Kaur R, Saade D, Moore SA, Waddell LB, Farrar MA, Goodrich JK, Uapinyoying P, Chan SHS, Javed A, Leach ME, Karachunski P, Dalton J, Medne L, Harper A, Thompson C, Thiffault I, Specht S, Lamont RE, Saunders C, Racher H, Bernier FP, Mowat D, Witting N, Vissing J, Hanson R, Coffman KA, Hainlen M, Parboosingh JS, Carnevale A, Yoon G, Schnur RE; Care4Rare Canada Consortium, Boycott KM, Mah JK, Straub V, Foley AR, Innes AM, Bönnemann CG, Shutt TE. Acta Neuropathol. 2019 Aug 29. doi: 10.1007/s00401-019-02059-z. [Epub ahead of print].

SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway. Sun X, Wang S, Gai J, Guan J, Li J, Li Y, Zhao J, Zhao C, Fu L, Li Q. Front Oncol. 2019 Aug 13;9:754. doi: 10.3389/fonc.2019.00754. eCollection 2019.

Week of August 27, 2019
Pityriasis rubra pilaris-like eruption in the setting of transient acantholytic dermatosis. View full article in JAAD Case Reports. Brown-Joel ZO, Chung J, Stone MS. JAAD Case Rep. 2019 Aug 5;5(8):733-735. doi: 10.1016/j.jdcr.2019.06.025. eCollection 2019 Aug. No abstract available.

Durable Clinical Benefit in Patients with Advanced Cutaneous Melanoma after Discontinuation of Anti-PD-1 Therapies Due to Immune-Related Adverse Events. Swami U, Monga V, Bossler AD, Zakharia Y, Milhem M. J Oncol. 2019 Jul 25;2019:1856594. doi: 10.1155/2019/1856594. eCollection 2019.

In Vitro Activity of Minocycline against U.S. Isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus species complex, Stenotrophomonas maltophilia, and Burkholderia cepacia complex: Results from the SENTRY Antimicrobial Surveillance Program (2014-2018). Flamm RK, Shortridge D, Castanheira M, Sader HS, Pfaller MA. Antimicrob Agents Chemother. 2019 Aug 19. pii: AAC.01154-19. doi: 10.1128/AAC.01154-19. [Epub ahead of print].

First-in-human phase 1 clinical trial of pharmacological ascorbate combined with radiation and temozolomide for newly diagnosed glioblastoma. Bodeker KL, Allen BG, Smith MC, Monga V, Sandhu S, Hohl RJ, Carlisle TL, Brown HA, Hollenbeck NJ, Vollstedt S, Greenlee JDW, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg DJ, Wagner BA, Buettner GR, TenNapel MJ, Smith BJ, Spitz DR, Buatti JM. Clin Cancer Res. 2019 Aug 19. pii: clincanres.0594.2019. doi: 10.1158/1078-0432.CCR-19-0594. [Epub ahead of print].

Response to letter regarding "An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses". View full article in Radiotherapy and Oncology. Spitz DR, Buettner GR, Limoli CL. Radiother Oncol. 2019 Aug 16. pii: S0167-8140(19)32999-8. doi: 10.1016/j.radonc.2019.07.009. [Epub ahead of print] No abstract available.

Week of August 20, 2019
Src-dependent DBL family members drive resistance to vemurafenib in human melanoma. Feddersen CR, Schillo JL, Varzavand A, Vaughn HR, Wadsworth LS, Voigt AP, Zhu EY, Jennings BM, Mullen SA, Bobera J, Riordan JD, Stipp CS, Dupuy AJ. Cancer Res. 2019 Aug 15. pii: canres.0244.2019. doi: 10.1158/0008-5472.CAN-19-0244. [Epub ahead of print].

Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. mSphere. 2019 Aug 14;4(4). pii: e00553-19. doi: 10.1128/mSphere.00553-19.

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization. Huggins MA, Sjaastad FV, Pierson M, Kucaba TA, Swanson W, Staley C, Weingarden AR, Jensen IJ, Danahy DB, Badovinac VP, Jameson SC, Vezys V, Masopust D, Khoruts A, Griffith TS, Hamilton SE. Cell Rep. 2019 Aug 13;28(7):1729-1743.e5. doi: 10.1016/j.celrep.2019.07.028.

Week of August 13, 2019
Incidence and Survival Among Young Women With Stage I-III Breast Cancer: SEER 2000-2015. Thomas A, Rhoads A, Pinkerton E, Schroeder MC, Conway KM, Hundley WG, McNally LR, Oleson J, Lynch CF, Romitti PA. JNCI Cancer Spectr. 2019 Jun 7;3(3):pkz040. doi: 10.1093/jncics/pkz040. eCollection 2019 Sep.

Week of August 6, 2019
t(15; 17) associated with primary myelofibrosis: a case report of an unusual clinical presentation and diagnostic dilemma. Nadiminti K, Silverman M, Bhagavathi S, Vikas P. Onco Targets Ther. 2019 Jul 11;12:5449-5455. doi: 10.2147/OTT.S208290. eCollection 2019.

Adverse Effects Profile of Dicycloplatin (DCP) Offers Chemotherapeutic Advantage Over Cisplatin and Carboplatin. Yu JJ, Hogan T, Morley C, Crigger C, Jiao S, Williams DJ, Salkini MW, Yang X, Liang X, Yan B, Cecil C, Winn AC, Zheng J, Guo YI, Jiang BH, Washington IM. Anticancer Res. 2019 Aug;39(8):4455-4462. doi: 10.21873/anticanres.13618.

Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism. Petronek MS, Spitz DR, Buettner GR, Allen BG. Cancers (Basel). 2019 Jul 30;11(8). pii: E1077. doi: 10.3390/cancers11081077. Review.

Week of July 30, 2019
Identification of Novel Respiratory Syncytial Virus CD4+ and CD8+ T Cell Epitopes in C57BL/6 Mice. Schmidt ME, Varga SM. Immunohorizons. 2019 Jan 14;3(1):1-12. doi: 10.4049/immunohorizons.1800056.

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB Jr, Meyerholz DK, Perlman S. J Clin Invest. 2019 Jul 29;130. pii: 126363. doi: 10.1172/JCI126363. eCollection 2019 Jul 29.

A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab. Espinosa-Cotton M, Fertig EJ, Stabile LP, Gaither-Davis A, Bauman JE, Schmitz S, Gibson-Corley KN, Cheng Y, Jensen IJ, Badovinac VP, Laux D, Simons AL. Biomark Res. 2019 Jul 16;7:14. doi: 10.1186/s40364-019-0164-0. eCollection 2019.

Predictive Markers Require Thorough Analytic Validation. Troxell ML, Fulton RS, Swanson PE, Bellizzi AM, Fitzgibbons PL, Ambaye AB, Haas TS, Goldsmith JD, Loykasek PA, Miller DV, O'Malley D, Qiu J, Salama ME, Schaberg KB, Schwartz RA, Shia J, Summers TA Jr, Wu Y. Arch Pathol Lab Med. 2019 Aug;143(8):907-909. doi: 10.5858/arpa.2019-0112-LE. No abstract available.

Sleeping Beauty Mouse Models of Cancer: Microenvironmental Influences on Cancer Genetics. Guimaraes-Young A, Feddersen CR, Dupuy AJ. Front Oncol. 2019 Jul 9;9:611. doi: 10.3389/fonc.2019.00611. eCollection 2019. Review.

SOD1 deficiency: a novel syndrome distinct from amyotrophic lateral sclerosis. Park JH, Elpers C, Reunert J, McCormick ML, Mohr J, Biskup S, Schwartz O, Rust S, Grüneberg M, Seelhöfer A, Schara U, Boltshauser E, Spitz DR, Marquardt T. Brain. 2019 Aug 1;142(8):2230-2237. doi: 10.1093/brain/awz182.

Week of July 23, 2019
An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research. Brayton CF, Boyd KL, Everitt JL, Meyerholz DK, Treuting PM, Bolon B. ILAR J. 2018 Dec 1;59(1):1-3. doi: 10.1093/ilar/ilz008.

Interstitial lung disease associated with anti-PM-Scl antibody: A single center experience. Ussavarungsi K, Nugent K, Gerke AK, Krasowski MD, Tuetken RS, Lenert PS. Autoimmun Rev. 2019 Jul 16:102355. doi: 10.1016/j.autrev.2019.102355. [Epub ahead of print] No abstract available.

Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. Rajan A, Gibson-Corley KN, Choi AB, Ofori-Amanfo GK, Ten Eyck P, Espinosa-Cotton M, Sperry SM, Simons AL. J Oncol. 2019 Jun 19;2019:5859680. doi: 10.1155/2019/5859680. eCollection 2019.

Interpretation and Utility of Drug of Abuse Screening Immunoassays: Insights From Laboratory Drug Testing Proficiency Surveys. Krasowski MD, McMillin GA, Melanson SEF, Dizon A, Magnani B, Snozek CLH. Arch Pathol Lab Med. 2019 Jul 17. doi: 10.5858/arpa.2018-0562-CP. [Epub ahead of print].

Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells. Martin MD, Jensen IJ, Ishizuka AS, Lefebvre M, Shan Q, Xue HH, Harty JT, Seder RA, Badovinac VP. J Clin Invest. 2019 Jun 20;130. pii: 124443. doi: 10.1172/JCI124443.

Week of July 16, 2019
The clinical characteristics of melanoma with BRAF V600R mutation: a case series study. Malkhasyan KA, Rooney SL, Snow AN, Swick BL, Milhem MM, Zakharia Y. Melanoma Res. 2019 Jul 11. doi: 10.1097/CMR.0000000000000630. [Epub ahead of print].

BK virus histopathologic disease severity does not predict allograft outcome in renal transplant recipients. Sanders ML, Swee M, Fraer M, Kuppachi S, Ten Eyck P, Rastogi P. Ann Diagn Pathol. 2019 Jun 27;42:1-6. doi: 10.1016/j.anndiagpath.2019.06.012. [Epub ahead of print].

Magnetic Resonance Imaging characteristics in case of TOR1AIP1 muscular dystrophy. Bhatia A, Mobley BC, Cogan J, Koziura ME, Brokamp E, Phillips J, Newman J; Undiagnosed Diseases Network (UDN), Moore SA, Hamid R; Members of the Undiagnosed Diseases Network. Clin Imaging. 2019 Jun 21;58:108-113. doi: 10.1016/j.clinimag.2019.06.010. [Epub ahead of print].

Unilateral Nasal Mass in a Woman in Her 20s. View full article in JAMA Otolaryngology-Head Neck Surgery. Tasche KK, Samuelson MI, Pagedar NA. JAMA Otolaryngol Head Neck Surg. 2019 Jul 11. doi: 10.1001/jamaoto.2019.1671. [Epub ahead of print] No abstract available.

Week of July 9, 2019
Risk-Based Newborn Drug Testing in a Setting With a Low Prevalence of Maternal Drug Use. Wood KE, McMillin GA, Krasowski MD. Hosp Pediatr. 2019 Jul 5. pii: hpeds.2018-0256. doi: 10.1542/hpeds.2018-0256. [Epub ahead of print].

β-amyloid and Tau Pathology in the Aging Feline Brain. Fiock KL, Smith JD, Crary JF, Hefti MM. J Comp Neurol. 2019 Jul 4. doi: 10.1002/cne.24741. [Epub ahead of print].

Non-linear protein binding of phenytoin in clinical practice - development and validation of a mechanistic prediction model. Ter Heine R, Kane SP, Huitema ADR, Krasowski MD, van Maarseveen EM. Br J Clin Pharmacol . 2019 Jul 3. doi: 10.1111/bcp.14053. [Epub ahead of print].

Comparison of the In Vitro Susceptibility of Ceftolozane-Tazobactam With the Cumulative Susceptibility Rates of Standard Antibiotic Combinations When Tested Against Pseudomonas aeruginosa From ICU Patients With Bloodstream Infections or Pneumonia. Shortridge D, Pfaller MA, Arends SJR, Raddatz J, DePestel DD, Flamm RK. Open Forum Infect Dis. 2019 May 20;6(6):ofz240. doi: 10.1093/ofid/ofz240. eCollection 2019 Jun.

Week of July 2, 2019
The Use of an Electronic Health Record Patient Portal to Access Diagnostic Test Results by Emergency Patients at an Academic Medical Center: Retrospective Study. Foster B, Krasowski MD. J Med Internet Res. 2019 Jun 28;21(6):e13791. doi: 10.2196/13791.

Assessment of nociception and related quality of life measures in a porcine model of Neurofibromatosis type 1. Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, Weimer JM. Pain. 2019 Jun 25. doi: 10.1097/j.pain.0000000000001648. [Epub ahead of print].

Pyogenic granuloma-like orf in a transplant patient treated successfully with excision and imiquimod. View full article in JAAD Case Reports. Harms J, Swick BL, Wanat KA. JAAD Case Rep. 2019 Jun 12;5(6):566-567. doi: 10.1016/j.jdcr.2019.02.035. eCollection 2019 Jun. No abstract available.

SMCHD1 mutation spectrum for facioscapulohumeral muscular dystrophy type 2 (FSHD2) and Bosma arhinia microphthalmia syndrome (BAMS) reveals disease-specific localisation of variants in the ATPase domain. Lemmers RJLF, van der Stoep N, Vliet PJV, Moore SA, San Leon Granado D, Johnson K, Topf A, Straub V, Evangelista T, Mozaffar T, Kimonis V, Selvatici R, Ferlini A, Voermans N, van Engelen B, Sacconi S, Tawil R, Lamers M, van der Maarel SM. J Med Genet. 2019 Jun 26. pii: jmedgenet-2019-106168. doi: 10.1136/jmedgenet-2019-106168. [Epub ahead of print].

Airway surface liquid has innate antiviral activity that is reduced in cystic fibrosis. Berkebile AR, Bartlett JA, Abou Alaiwa M, Varga SM, Power UF, McCray PB Jr. Am J Respir Cell Mol Biol. 2019 Jun 26. doi: 10.1165/rcmb.2018-0304OC. [Epub ahead of print].

Week of June 25, 2019
SATB2 in Neuroendocrine Neoplasms: Strong Expression is Restricted to Well-Differentiated Tumors of Lower Gastrointestinal Tract Origin and is More Frequent in Merkel Cell Carcinoma among Poorly Differentiated Carcinomas. Bellizzi AM. Histopathology. 2019 Jun 24. doi: 10.1111/his.13943. [Epub ahead of print].

Creating Pathologists From a Post-Sophomore Pathology Fellowship: 21 Years and 126 Fellows at an Academic Pathology Department. Isaacson AL, Robinson RA, Samuelson MI. Acad Pathol. 2019 Jun 10;6:2374289519851203. doi: 10.1177/2374289519851203. eCollection 2019 Jan-Dec.

A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. Feddersen CR, Wadsworth LS, Zhu EY, Vaughn HR, Voigt AP, Riordan JD, Dupuy AJ. BMC Genomics. 2019 Jun 17;20(1):497. doi: 10.1186/s12864-019-5888-6.

Impact of Nuclear Interleukin-1 Alpha and EGFR Expression on Recurrence and Survival Outcomes in Oral Squamous Cell Carcinomas. Rajan A, Gibson-Corley KN, Choi AB, Ofori-Amanfo GK, Ten-Eyck P, Espinosa-Cotton M, Sperry SM, Simons AL. Journal of Oncology, vol. 2019, Article ID 5859680, 12 pages, 2019.

Prevalence and cervical organism burden among Louisiana women with Trichomonas vaginalis infections. Shaw MK, Porterfield HS, Favaloro S, Dehon PM, Van Der Pol B, Quayle AJ, McGowin CL. PLoS One. 2019 Jun 20;14(6):e0217041. doi: 10.1371/journal.pone.0217041. eCollection 2019.

Week of June 18, 2019
Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease. Kim Y, Liu G, Leugers CJ, Mueller JD, Francis MB, Hefti MM, Schneider JA, Lee G. J Cell Sci. 2019 Jun 14. pii: jcs.229054. doi: 10.1242/jcs.229054. [Epub ahead of print].

Acute hydrocephalus resulting from neuromyelitis optica: A case report and review of the literature. Close LN, Zanaty M, Kirby P, Dlouhy BJ. World Neurosurg. 2019 Jun 11. pii: S1878-8750(19)31454-8. doi: 10.1016/j.wneu.2019.05.177. [Epub ahead of print].

Massive Scalp Cylindromas Treated With Staged Resection and Split-Thickness Skin Grafting. Shearer AE, Vidholia A, Jensen CS, Bayon R. JAMA Otolaryngol Head Neck Surg. 2019 Jun 13. doi: 10.1001/jamaoto.2019.1234. [Epub ahead of print] No abstract available.

Sepsis-Induced State of Immunoparalysis Is Defined by Diminished CD8 T Cell-Mediated Antitumor Immunity. Danahy DB, Kurup SP, Winborn CS, Jensen IJ, Harty JT, Griffith TS, Badovinac VP. J Immunol. 2019 Jun 12. pii: ji1900435. doi: 10.4049/jimmunol.1900435. [Epub ahead of print].

In Vitro Activity of APX001A (Manogepix) and Comparator Agents against 1,706 Fungal Isolates Collected During an International Surveillance Program (2017). Pfaller MA, Huband MD, Flamm RK, Bien PA, Castanheira M. Antimicrob Agents Chemother. 2019 Jun 10. pii: AAC.00840-19. doi: 10.1128/AAC.00840-19. [Epub ahead of print].

Week of June 11, 2019
Projected Prevalence of Actionable Pharmacogenetic Variants and Level A Drugs Prescribed Among US Veterans Health Administration Pharmacy Users. Chanfreau-Coffinier C, Hull LE, Lynch JA, DuVall SL, Damrauer SM, Cunningham FE, Voight BF, Matheny ME, Oslin DW, Icardi MS, Tuteja S. JAMA Netw Open. 2019 Jun 5;2(6):e195345. doi: 10.1001/jamanetworkopen.2019.5345.

Renal Denervation and CD161a Immune Ablation Prevent Cholinergic Hypertension and Renal Sodium Retention. Raikwar NS, Braverman C, Snyder PM, Fenton RA, Meyerholz DK, Abboud FM, Harwani SC. Am J Physiol Heart Circ Physiol. 2019 Jun 7. doi: 10.1152/ajpheart.00234.2019. [Epub ahead of print].

Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation. He J, Liu W, Ge X, Wang GC, Desai V, Wang S, Mu W, Bhardwaj V, Seifert E, Liu LZ, Bhushan A, Peiper SC, Jiang BH. Toxicol Appl Pharmacol. 2019 Jun 3:114606. doi: 10.1016/j.taap.2019.114606. [Epub ahead of print].

Response to "Be alert to leukocyte antibodies when prescribing granulocyte transfusions". Price TH, McCullough J, Strauss RG, Ness PM, Hamza TH, Harrison RW, Assmann SF. Transfusion. 2019 Jun;59(6):2174-2175. doi: 10.1111/trf.15258. No abstract available.

Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations. Meng X, Yang S, Li Y, Li Y, Devor EJ, Bi J, Wang X, Umesalma S, Quelle DE, Thiel WH, Thiel KW, Leslie KK. Dis Markers. 2018 Dec 17;2018:3810108. doi: 10.1155/2018/3810108. eCollection 2018.

Week of June 4, 2019
ANNALS EXPRESS: Novel ketamine analogs cause a false positive phencyclidine immunoassay. Skaugen JM, Scoccimarro A, Pizon AF, Rymer JA, Giannoutsos S, Ekins S, Krasowski MD, Tamama K. Ann Clin Biochem. 2019 Jun 1:4563219858125. doi: 10.1177/0004563219858125. [Epub ahead of print].

Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth. Wang L, Qiu JG, He J, Liu WJ, Ge X, Zhou FM, Huang YX, Jiang BH, Liu LZ. Toxicol Appl Pharmacol. 2019 May 29:114603. doi: 10.1016/j.taap.2019.114603. [Epub ahead of print].

Burden and Characteristics of Unsolicited Emails from Medical/Scientific Journals, Conferences, and Webinars to Faculty and Trainees at an Academic Pathology Department. Krasowski MD, Lawrence JC, Briggs AS, Ford BA. J Pathol Inform. 2019 May 6;10:16. doi: 10.4103/jpi.jpi_12_19. eCollection 2019.

Immunophenotypic Heterogeneity of Polytypic Plasma Cells and the Impact on Myeloma Minimal Residual Disease Detection by Multiparameter Flow Cytometry. Schouweiler KE, Karandikar NJ, Holman CJ. Cytometry B Clin Cytom. 2019 May 29. doi: 10.1002/cyto.b.21789. [Epub ahead of print].

Cancer incidence in the Agricultural Health Study after 20 years of follow-up. Lerro CC, Koutros S, Andreotti G, Sandler DP, Lynch CF, Louis LM, Blair A, Parks CG, Shrestha S, Lubin JH, Albert PS, Hofmann JN, Beane Freeman LE. Cancer Causes Control. 2019 Apr;30(4):311-322. doi: 10.1007/s10552-019-01140-y. Epub 2019 Feb 25.

Week of May 28, 2019
Treatment trends in head and neck cancer: Surveillance, Epidemiology, and End Results (SEER) Patterns of Care analysis. Schlichting JA, Pagedar NA, Chioreso C, Lynch CF, Charlton ME. Cancer Causes Control. 2019 May 22. doi: 10.1007/s10552-019-01185-z. [Epub ahead of print].

Patient with a PRKAG2 mutation who developed Immunoglobulin A nephropathy: a case report. Giudici MC, Ahmad F, Holanda DG. European Heart Journal – Case Reports, ytz038.

Week of May 21, 2019
Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma. Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell S, Feldman AL. Blood. 2019 May 17. pii: blood.2019000626. doi: 10.1182/blood.2019000626. [Epub ahead of print].

Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation. de Greef JC, Slütter B, Anderson ME, Hamlyn R, O'Campo Landa R, McNutt EJ, Hara Y, Pewe LL, Venzke D, Matsumura K, Saito F, Harty JT, Campbell KP. Proc Natl Acad Sci U S A. 2019 May 16. pii: 201904493. doi: 10.1073/pnas.1904493116. [Epub ahead of print].

Histopathology of Anterior Urethral Strictures: Towards a Better Understanding of Stricture Pathophysiology. Grimes MD, Tesdahl BA, Schubbe M, Dahmoush L, Pearlman AM, Kreder KJ, Erickson BA. J Urol. 2019 May 15:101097JU0000000000000340. doi: 10.1097/JU.0000000000000340. [Epub ahead of print].

Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism. Rashmi R, Huang X, Floberg JM, Elhammali AE, McCormick ML, Patti GJ, Spitz DR, Schwarz JK. Cancer Res. 2018 Mar 15;78(6):1392-1403. doi: 10.1158/0008-5472.CAN-17-2367. Epub 2018 Jan 16.

Antimicrobial activity of oritavancin and comparator agents when tested against Gram-positive bacterial isolates causing infections in cancer patients (2014-16). Pfaller MA, Sader HS, Castanheira M, Flamm RK, Mendes RE. J Antimicrob Chemother. 2018 Apr 1;73(4):916-922. doi: 10.1093/jac/dkx485.

Week of May 14, 2019
Activity of tedizolid against gram-positive clinical isolates causing infections in Europe and surrounding areas (2014-2015). Pfaller MA, Sader HS, Shortridge D, Castanheira M, Flamm RK, Mendes RE. J Chemother. 2019 May 13:1-7. doi: 10.1080/1120009X.2019.1609740. [Epub ahead of print].

Dermal elastolysis in the setting of combination immunotherapy. Dickinson KE, Price L, Wanat KA, Swick BL. J Cutan Pathol. 2019 May 10. doi: 10.1111/cup.13492. [Epub ahead of print].

Modulation of B cell activation threshold mediated by BCR/CD40 costimulation by targeting Cbl-b for ubiquitination. Tang N, Yang L, Li D, Liu R, Zhang J. Biochem Biophys Rep. 2019 Apr 28;18:100641. doi: 10.1016/j.bbrep.2019.100641. eCollection 2019 Jul.

Week of May 7, 2019
Laboratory Diagnosis and Monitoring of Viral Hepatitis. Prasidthrathsint K, Stapleton JT. Gastroenterol Clin North Am. 2019 Jun;48(2):259-279. doi: 10.1016/j.gtc.2019.02.007. Epub 2019 Apr 1. Review.

Clinical, genetic, and pathologic characterization of FKRP Mexican founder mutation c.1387A>G. Lee AJ, Jones KA, Butterfield RJ, Cox MO, Konersman CG, Grosmann C, Abdenur JE, Boyer M, Beson B, Wang C, Dowling JJ, Gibbons MA, Ballard A, Janas JS, Leshner RT, Donkervoort S, Bönnemann CG, Malicki DM, Weiss RB, Moore SA, Mathews KD. Neurol Genet. 2019 Mar 1;5(2):e315. doi: 10.1212/NXG.0000000000000315. eCollection 2019 Apr.

Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation. Koval OM, Nguyen EK, Santhana V, Fidler TP, Sebag SC, Rasmussen TP, Mittauer DJ, Strack S, Goswami PC, Abel ED, Grumbach IM. Sci Signal. 2019 Apr 30;12(579). pii: eaav1439. doi: 10.1126/scisignal.aav1439.

Assessment of the Stability of Supraphysiological Ascorbate in Human Blood: Appropriate Handling of Samples from Clinical Trials For Measurements of Pharmacological Ascorbate. Petronek MS, Wagner BA, Hollenbeck NJ, Caster JM, Spitz DR, Cullen JJ, Buettner GR, Allen BG. Radiat Res. 2019 Apr 30. doi: 10.1667/RR15328.1. [Epub ahead of print].

Glioma grading using structural magnetic resonance imaging and molecular data. Reza SMS, Samad MD, Shboul ZA, Jones KA, Iftekharuddin KM. J Med Imaging (Bellingham). 2019 Apr;6(2):024501. doi: 10.1117/1.JMI.6.2.024501. Epub 2019 Apr 24.

Krasowski MD, Wagar EA, Cohen MB. Chapter 15: Ethics for Pathology and Laboratory Medicine. In: Wager EA et al, eds. Wagar, Horowitz, & Siegal’s Laboratory Administration for Pathologists. 2nd edition. Northfield (Illinois): College of American Pathologists, 2019, pp. 261-272.

Week of April 30, 2019
Cancer-attributable mortality among solid organ transplant recipients in the United States: 1987 through 2014. Noone AM, Pfeiffer RM, Dorgan JF, Magder LS, Bromberg JS, Lynch CF, Morris CR, Pawlish KS, Engels EA. Cancer. 2019 Apr 29. doi: 10.1002/cncr.32136. [Epub ahead of print].

Comparing high-dose cisplatin with cisplatin-based combination chemotherapy in definitive concurrent chemoradiation setting for locally advanced head and neck squamous cell carcinoma (LAHNSCC). Furqan M, Snyders TP, Saqlain MU, Mott SL, Laux D, Snow A, Anderson CM, Watkins JM, Clamon GH. Cancer Med. 2019 Apr 9. doi: 10.1002/cam4.2139. [Epub ahead of print].

Pathogen acquisition in patients with cystic fibrosis receiving ivacaftor or lumacaftor/ivacaftor. Singh SB, McLearn-Montz AJ, Milavetz F, Gates LK, Fox C, Murry LT, Sabus A, Porterfield HS, Fischer AJ. Pediatr Pulmonol. 2019 Apr 22. doi: 10.1002/ppul.24341. [Epub ahead of print].

The Pancreas as a Site of Metastasis or Second Primary in Patients with Small Bowel Neuroendocrine Tumors. Scott AT, Pelletier D, Maxwell JE, Sherman SK, Keck KJ, Li G, Dillon JS, O'Dorisio TM, Bellizzi AM, Howe JR. Ann Surg Oncol. 2019 Apr 22. doi: 10.1245/s10434-019-07370-3. [Epub ahead of print].

Urothelial carcinoma with an NRF1/BRAF rearrangement and response to targeted therapy. Isaacson AL, Guseva NV, Bossler AD, Ma D. Cold Spring Harb Mol Case Stud. 2019 Apr 22. pii: mcs.a003848. doi: 10.1101/mcs.a003848. [Epub ahead of print].

The Microbiology of Bloodstream Infection: 20-Year Trends from the SENTRY Antimicrobial Surveillance Program. Diekema DJ, Hsueh PR, Mendes RE, Pfaller MA, Rolston KV, Sader HS, Jones RN. Antimicrob Agents Chemother. 2019 Apr 22. pii: AAC.00355-19. doi: 10.1128/AAC.00355-19. [Epub ahead of print].

An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses. Spitz DR, Buettner GR, Petronek MS, St-Aubin JJ, Flynn RT, Waldron TJ, Limoli CL. Radiother Oncol. 2019 Apr 19. pii: S0167-8140(19)30150-1. doi: 10.1016/j.radonc.2019.03.028. [Epub ahead of print].

The association between United States Medical Licensing Examination scores and clinical performance in medical students. Gauer JL, Jackson JB. Adv Med Educ Pract. 2019;10:209-216.

Week of April 23, 2019
Vaccination with a Single-Cycle Respiratory Syncytial Virus Is Immunogenic and Protective in Mice. Schmidt ME, Oomens AGP, Varga SM. J Immunol. 2019 Apr 19. pii: ji1900050. doi: 10.4049/jimmunol.1900050. [Epub ahead of print].

ACTA1-myopathy with prominent finger flexor weakness and rimmed vacuoles. Liewluck T, Niu Z, Moore SA, Alsharabati M, Milone M. Neuromuscul Disord. 2019 Mar 2. pii: S0960-8966(18)31278-1. doi: 10.1016/j.nmd.2019.02.012. [Epub ahead of print].

Week of April 16, 2019
Prevotella histicola, A Human Gut Commensal, Is as Potent as COPAXONE® in an Animal Model of Multiple Sclerosis. Shahi SK, Freedman SN, Murra AC, Zarei K, Sompallae R, Gibson-Corley KN, Karandikar NJ, Murray JA, Mangalam AK. Front Immunol. 2019 Mar 22;10:462. doi: 10.3389/fimmu.2019.00462. eCollection 2019.

Derivation of adult canine intestinal organoids for translational research in gastroenterology. Chandra L, Borcherding DC, Kingsbury D, Atherly T, Ambrosini YM, Bourgois-Mochel A, Yuan W, Kimber M, Qi Y, Wang Q, Wannemuehler M, Ellinwood NM, Snella E, Martin M, Skala M, Meyerholz D, Estes M, Fernandez-Zapico ME, Jergens AE, Mochel JP, Allenspach K. BMC Biol. 2019 Apr 11;17(1):33. doi: 10.1186/s12915-019-0652-6.

Cutting Edge: Polymicrobial Sepsis Has the Capacity to Reinvigorate Tumor-Infiltrating CD8 T Cells and Prolong Host Survival. Danahy DB, Jensen IJ, Griffith TS, Badovinac VP. J Immunol. 2019 Apr 10. pii: ji1900076. doi: 10.4049/jimmunol.1900076. [Epub ahead of print].

Clinical Challenges with Talimogene Laherparepvec: Cured Lymph Nodes Masquerading as Active Melanoma. Swami U, Swick B, Zakharia Y, Milhem M. Case Rep Oncol Med. 2019 Mar 7;2019:4683531. doi: 10.1155/2019/4683531. eCollection 2019.

Longitudinal investigation of haematological alterations among permethrin-exposed pesticide applicators in the Biomarkers of Exposure and Effect in Agriculture study. Shearer JJ, Beane Freeman LE, Liu D, Andreotti G, Hamilton J, Happel J, Lynch CF, Alavanja MC, Hofmann JN. Occup Environ Med. 2019 Apr 8. pii: oemed-2018-105559. doi: 10.1136/oemed-2018-105559. [Epub ahead of print].

Week of April 9, 2019
T cell-mediated immunity to malaria. Kurup SP, Butler NS, Harty JT. Nat Rev Immunol. 2019 Apr 2. doi: 10.1038/s41577-019-0158-z. [Epub ahead of print] Review.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice. Loeb KR, Hughes BT, Fissel BM, Osteen NJ, Knoblaugh SE, Grim JE, Drury LJ, Sarver A, Dupuy AJ, Clurman BE. Sci Rep. 2019 Apr 2;9(1):5488. doi: 10.1038/s41598-019-41805-x.

BCR-NTRK2 fusion in a low-grade glioma with distinctive morphology and unexpected aggressive behavior. Jones KA, Bossler AD, Bellizzi AM, Snow AN. Cold Spring Harb Mol Case Stud. 2019 Apr 1;5(2). pii: a003855. doi: 10.1101/mcs.a003855. Print 2019 Apr.

Week of April 2, 2019
Aberrant regulation of epigenetic modifiers contributes to the pathogenesis in patients with selenoprotein N-related myopathies. Bachmann C, Noreen F, Voermans NC, Schär PL, Vissing J, Fock JM, Bulk S, Kusters B, Moore SA, Beggs AH, Mathews KD, Meyer M, Genetti CA, Meola G, Cardani R, Mathews E, Jungbluth H, Muntoni F, Zorzato F, Treves S. Hum Mutat. 2019 Apr 1. doi: 10.1002/humu.23745. [Epub ahead of print].

Human papillomavirus DNA detection, p16INK4a, and oral cavity cancer in a U.S. population. Hernandez BY, Lynch CF, Chan OTM, Goodman MT, Unger ER, Steinau M, Thompson TD, Gillison M, Lyu C, Saraiya M; HPV Typing of Cancer Workgroup. Oral Oncol. 2019 Apr;91:92-96. doi: 10.1016/j.oraloncology.2019.03.001. Epub 2019 Mar 5.

In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis. Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7531. doi: 10.1126/scitranslmed.aau7531.

The utility of prognostic indices, early events, and histological subtypes on predicting outcomes in non-follicular indolent B-cell lymphomas. Tracy SI, Larson MC, Feldman AL, Maurer MJ, Novak AJ, Slager SL, Villasboas JC, Allmer C, Habermann TM, Farooq U, Syrbu S, Cerhan JR, Link BK. Am J Hematol. 2019 Mar 27. doi: 10.1002/ajh.25473. [Epub ahead of print].

Week of March 26, 2019
Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye. van der Heide CJ, Alward WLM, Flamme-Wiese M, Riker M, Syed NA, Anderson MG, Carter K, Kuehn MH, Stone EM, Mullins RF, Fingert JH. Ophthalmol Glaucoma. 2018 Sep-Oct;1(2):132-138. doi: 10.1016/j.ogla.2018.08.004. Epub 2018 Aug 17.

Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria. Kurup SP, Anthony SM, Hancox LS, Vijay R, Pewe LL, Moioffer SJ, Sompallae R, Janse CJ, Khan SM, Harty JT. Cell Host Microbe. 2019 Mar 13. pii: S1931-3128(19)30110-6. doi: 10.1016/j.chom.2019.02.014. [Epub ahead of print].

Nonmetropolitan residence and other factors affecting clinical trial enrollment for adolescents and young adults with cancer in a US population-based study. Mobley EM, Charlton ME, Ward MM, Lynch CF. Cancer. 2019 Mar 22. doi: 10.1002/cncr.32038. [Epub ahead of print].

Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997-2016. Pfaller MA, Diekema DJ, Turnidge JD, Castanheira M, Jones RN. Open Forum Infect Dis. 2019 Mar 15;6(Suppl 1):S79-S94. doi: 10.1093/ofid/ofy358. eCollection 2019 Mar.

Temporal and Geographic Variation in Antimicrobial Susceptibility and Resistance Patterns of Enterococci: Results From the SENTRY Antimicrobial Surveillance Program, 1997-2016. Pfaller MA, Cormican M, Flamm RK, Mendes RE, Jones RN. Open Forum Infect Dis. 2019 Mar 15;6(Suppl 1):S54-S62. doi: 10.1093/ofid/ofy344. eCollection 2019 Mar.

Twenty-Year Trends in Antimicrobial Susceptibilities Among Staphylococcus aureus From the SENTRY Antimicrobial Surveillance Program. Diekema DJ, Pfaller MA, Shortridge D, Zervos M, Jones RN. Open Forum Infect Dis. 2019 Mar 15;6(Suppl 1):S47-S53. doi: 10.1093/ofid/ofy270. eCollection 2019 Mar.

Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma. Espinosa-Cotton M, Rodman Iii SN, Ross KA, Jensen IJ, Sangodeyi-Miller K, McLaren AJ, Dahl RA, Gibson-Corley KN, Koch AT, Fu YX, Badovinac VP, Laux D, Narasimhan B, Simons AL. J Immunother Cancer. 2019 Mar 19;7(1):79. doi: 10.1186/s40425-019-0550-z.

Week of March 19, 2019
The Role of Redox Dysregulation in the Effects of Prenatal Stress on Embryonic Interneuron Migration. Bittle J, Menezes EC, McCormick ML, Spitz DR, Dailey M, Stevens HE. Cereb Cortex. 2019 Mar 16. pii: bhz052. doi: 10.1093/cercor/bhz052. [Epub ahead of print].

Week of March 12, 2019
Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma. Davis K, Dunseth CD, Mott SL, Cramer-Morales KL, Miller AM, Ear PH, Mezhir JJ, Bellizzi AM, Chan CHF. PLoS One. 2019 Mar 11;14(3):e0213576. doi: 10.1371/journal.pone.0213576. eCollection 2019.

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells. Xing S, Gai K, Li X, Shao P, Zeng Z, Zhao X, Zhao X, Chen X, Paradee WJ, Meyerholz DK, Peng W, Xue HH. J Exp Med. 2019 Mar 5. pii: jem.20182010. doi: 10.1084/jem.20182010. [Epub ahead of print].

Week of March 5, 2019
Exceptional responses with sequential metronomic temozolomide after pembrolizumab failure in patients with metastatic melanoma. Swami U, Monga V, Freesmeier M, Zhang W, Bossler AD, Zakharia Y, Milhem M. Melanoma Res. 2019 Mar 1. doi: 10.1097/CMR.0000000000000592. [Epub ahead of print].

Tissue plasminogen activator vs heparin for locking central venous catheters between apheresis procedures. Mathur G, Mott SL, Collins L, Schlueter AJ. J Clin Apher. 2019 Mar 4. doi: 10.1002/jca.21697. [Epub ahead of print].

Laboratory practices for identification and reporting of carbapenem-resistant Enterobacteriaceae in Department of Veterans Affairs facilities. Fitzpatrick MA, Suda KJ, Ramanathan S, Guihan M, Brown C, Safdar N, Evans M, Jones MM, Pfeiffer CD, Klutts JS, Icardi M, Perencevich E, Rubin M, Evans CT; QUERI CARRIAGE Program. Infect Control Hosp Epidemiol. 2019 Mar 4:1-4. doi: 10.1017/ice.2019.24. [Epub ahead of print].

Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease. Gonorazky HD, Naumenko S, Ramani AK, Nelakuditi V, Mashouri P, Wang P, Kao D, Ohri K, Viththiyapaskaran S, Tarnopolsky MA, Mathews KD, Moore SA, Osorio AN, Villanova D, Kemaladewi DU, Cohn RD, Brudno M, Dowling JJ. Am J Hum Genet. 2019 Feb 20. pii: S0002-9297(19)30012-6. doi: 10.1016/j.ajhg.2019.01.012. [Epub ahead of print].

Surveillance of omadacycline activity tested against clinical isolates from the United States and Europe: Results from the SENTRY Antimicrobial Surveillance Programme, 2017. Huband MD, Pfaller MA, Shortridge D, Flamm RK. J Glob Antimicrob Resist. 2019 Feb 27. pii: S2213-7165(19)30057-8. doi: 10.1016/j.jgar.2019.02.017. [Epub ahead of print].

Cancer risk following post-transplant lymphoproliferative disorders in solid organ transplant recipients. Mahale P, Engels EA, Lynch CF, Morton LM. Br J Haematol. 2019 Feb 28. doi: 10.1111/bjh.15828. [Epub ahead of print] No abstract available.

Accidental intoxications in toddlers: lack of cross-reactivity of vilazodone and its urinary metabolite M17 with drug of abuse screening immunoassays. Martinez-Brokaw CD, Radke JB, Pierce JG, Ehlers A, Ekins S, Wood KE, Maakestad J, Rymer JA, Tamama K, Krasowski MD. BMC Clin Pathol. 2019 Feb 18;19:2. doi: 10.1186/s12907-019-0084-9. eCollection 2019.

Verrucous carcinoma: An unexpected finding arising from a burn scar. Hannah CE, Weig EA, Collier S, Stone MS, Juma O, Mcharo JJ, Ferguson NN, Wanat KA. JAAD Case Rep. 2019 Feb 12;5(3):225-227. doi: 10.1016/j.jdcr.2018.12.006. eCollection 2019 Mar. No abstract available.

Resolution of pseudoainhum with acitretin therapy in a patient with palmoplantar keratoderma and congenital alopecia. Richey PM, Stone MS. JAAD Case Rep. 2019 Feb 12;5(3):219-221. doi: 10.1016/j.jdcr.2018.12.004. eCollection 2019 Mar. No abstract available.

Ceftobiprole activity when tested against contemporary bacteria causing bloodstream infections in the United States (2016-2017). Pfaller MA, Flamm RK, Duncan LR, Shortridge D, Smart JI, Hamed KA, Mendes RE, Sader HS. Diagn Microbiol Infect Dis. 2019 Jan 26. pii: S0732-8893(18)30625-4. doi: 10.1016/j.diagmicrobio.2019.01.015. [Epub ahead of print].

Utilizing Superoxide Dismutase Mimetics to Enhance Radiation Therapy Response While Protecting Normal Tissues. Mapuskar KA, Anderson CM, Spitz DR, Batinic-Haberle I, Allen BG, E Oberley-Deegan R. Semin Radiat Oncol. 2019 Jan;29(1):72-80. doi: 10.1016/j.semradonc.2018.10.005. Review.

Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio-Chemotherapy While Protecting Normal Tissue. Schoenfeld JD, Alexander MS, Waldron TJ, Sibenaller ZA, Spitz DR, Buettner GR, Allen BG, Cullen JJ. Semin Radiat Oncol. 2019 Jan;29(1):25-32. doi: 10.1016/j.semradonc.2018.10.006. Review.

Manipulations of Redox Metabolism for Enhancing Radiation Therapy Responses: A Historical Perspective and Novel Hypothesis. Spitz DR. Semin Radiat Oncol. 2019 Jan;29(1):1-5. doi: 10.1016/j.semradonc.2018.10.010. No abstract available.

Is More Always Better? An Assessment of the Impact of Lymph Node Yield on Outcome for Clinically Localized Prostate Cancer with Low/Intermediate Risk Pathology (pT2-3a/pN0) Managed with Prostatectomy Alone. Seyedin SN, Mitchell DL, Mott SL, Russo JK, Tracy CR, Snow AN, Parkhurst JR, Smith MC, Buatti JM, Watkins JM. Pathol Oncol Res. 2019 Jan;25(1):209-215. doi: 10.1007/s12253-017-0349-5. Epub 2017 Oct 27.

Week of February 26, 2019
Angiotensin II-induced Hypertension and Cardiac Hypertrophy are Differentially Mediated by TLR3- and TLR4-Dependent Pathways. Singh MV, Cicha MZ, Nunez S, Meyerholz DK, Chapleau MW, Abboud FM. Am J Physiol Heart Circ Physiol. 2019 Feb 22. doi: 10.1152/ajpheart.00697.2018. [Epub ahead of print].

Week of February 19, 2019
Verrucous cyst: Possible precursor of proliferating epidermoid cyst. Richey PM, Ferguson NN, Stone MS. J Cutan Pathol. 2019 Feb 17. doi: 10.1111/cup.13443. [Epub ahead of print].

Hematology reference intervals for transgender adults on stable hormone therapy. Greene DN, McPherson GW, Rongitsch J, Imborek KL, Schmidt RL, Humble RM, Nisly N, Dole NJ, Dane SK, Frerichs J, Krasowski MD. Clin Chim Acta. 2019 Feb 13. pii: S0009-8981(19)30063-4. doi: 10.1016/j.cca.2019.02.011. [Epub ahead of print].

Ventilatory response to CO2 in patients with epilepsy. Sainju RK, Dragon DN, Winnike HB, Nashelsky MB, Granner MA, Gehlbach BK, Richerson GB. Epilepsia. 2019 Feb 12. doi: 10.1111/epi.14660. [Epub ahead of print].