1. Home
  2. Faculty

Amani Bashir, MBBS

Clinical Associate Professor of Pathology

Introduction

Interests: Surgical Pathology and Cytology with special interest in Breast Pathology and an interest in Renal Pathology

Current Positions

  • Clinical Associate Professor of Pathology
  • Director, Surgical Pathology Fellowship Program
  • Director of Breast Pathology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA

Education

  • MBBS, University of Jordan
  • Transitional Intern in Medicine, Jordan University Hospital; Jordan Hospital; Al-Bashir Hospital, Amman, Jordan
  • Resident in Pathology, University of Jordan, Amman, Jordan
  • Resident in Pathology, University of Iowa Hospitals & Clinics, Iowa City, Iowa
  • Cytopathology Fellowship in Cytopathology, University of Iowa Hospitals & Clinics, Iowa City, Iowa
  • Surgical Pathology Fellowship in Surgical Pathology, University of Iowa Hospitals & Clinics, Iowa City, Iowa

Center, Program and Institute Affiliations

Research Interests

  • Clinical and translational research in breast pathology specifically breast cancer. Translational research in Cytopathology.
  • IHC features of solid papillary carcinoma (IRB #201502834 - collaboration with Dr. Andrew Bellizzi)
  • Basaloid squamous cell carcinoma of the head and neck, retrospective review and analysis of outcome
  • Vandetanib and breast cancer (IRB# 20130176 - collaboration with Dr. Ronald Weigel)
  • Expression of GPER in triple negative breast cancer (IRB# 201804832 - collaboration with Drs. Phadke and Filardo)
  • Nephrogenic ascites after renal transplantation (IRB# 201606844 - collaboration with Dr. Christi Thomas)
  • BST-2 as a predictive and prognostic bio-signature in breast cancer (IRB# 201607746 - collaboration with Dr. Cheoma Okeoma). Revised manuscript submitted.
  • Basaloid squamous cell carcinoma of the head and neck, assessment for loss of heterozygosity
  • Evaluating the clinical value of p120 catenin IHC in lobular breast cancer (IRB# 201505766 - principal investigator)
  • Outcomes of hormone receptor negative DCIS that expresses PD-L1 and IDO (IRB# 201706800 - collaboration with Dr. Sneha Phadke). Data collection completed.

Licenses & Certifications

  • Cytopathology Certification, American Board of Cytopathology
  • Anatomic and Clinical Pathology Certification, American Board of Pathology
  • State of Iowa Medical License, Iowa Board of Medicine, Iowa
  • Educational Commission of Foreign Medical Graduates

Selected Publications

  • Beck AC, Fu SL, Liao J, Bashir A, Sugg SL, Erdahl LM, Weigel RJ, Lizarraga IM. (2022). Risk management recommendations and patient acceptance vary with high-risk breast lesions. Am J Surg. 2022 Jan;223(1):94-100. doi: 10.1016/j.amjsurg.2021.07.020. Epub 2021 Jul 21. PMID: 34325908
  • Spanheimer PM, Bashir A, Lorenzen AW, Beck AC, Liao J, Lizarraga IM, Erdahl LM, Sugg SL, Karwal MW, Weigel RJ. (2021). A Pilot Study of Preoperative Vandetanib on Markers of Proliferation and Apoptosis in Breast Cancer. Am J Clin Oncol. 2021 Sep 1;44(9):456-462. doi: 10.1097/COC.0000000000000845. PMID: 34190716
  • Mahauad-Fernandez, W. D., Naushad, W., Panzner, T. D., Bashir, A., Lal, G. & Okeoma, C. M. BST-2 promotes survival in circulation and pulmonary metastatic seeding of breast cancer cells. Sci Rep. 2018 Dec 4;8(1):17608. doi: 10.1038/s41598-018-35710-y. PMID: 30514852
  • Masaadeh AH, Dundar B, Samuelson MI, Kadera E, Bashir A. (2024). Bilateral Somatically Derived Germ Cell Tumors With 12p Gains Arising in High-grade Serous Carcinomas of the Ovary: A Case Report and Review of the Literature. Int J Gynecol Pathol. 2024 Oct 30. doi: 10.1097/PGP.0000000000001074. Online ahead of print. PMID: 39475366
  • Albright, E. L., Keeney, M. E., Bashir, A. & Weigel, R. J. (2018). Poorly differentiated neuroendocrine carcinoma of the breast with Merkel cell features. (Vols. 24). (4), pp. 644-647. Breast J. DOI: 10.1111/tbj.12969. PMID: 29457684.
  • Hui J, Zhan X, Bashir A, Policeni F, Kim Hsieh S. (2024). Epithelial-myoepithelial carcinoma occurrence in the site of previously treated ductal carcinoma in situ of the breast: Imaging features with histopathologic correlation, a case report and review of the literature. Clin Case Rep. 2024 Aug 6;12(8):e9270. doi: 10.1002/ccr3.9270. eCollection 2024 Aug. PMID: 39114840
  • Moloney B., Li X., Hirano M, Eddin A.S. , Lim J.Y., Biswas D., Kazerouni A.S., Tudorica A., Isabella Li, Bryant M.L., Wille C., Pyle C., Rahbar H., Su Kim Hsieh, Rice-Stitt T., Dintzis S.M., Bashir A., Hobbs E., Zimmer A., Specht J.M., Phadke S., Fleege N., Holmes J.H., Partridge S.C., Huang W., (2024) Initial experience in implementing quantitative DCE-MRI to predict breast cancer therapy response in a multi-center and multi-vendor platform setting. Front. Oncol., 28 November 2024 Sec. Cancer Imaging and Image-directed Interventions Volume 14 - 2024 | https://doi.org/10.3389/fonc.2024.1395502
  • Guseva, N. V., Jaber, O., Stence, A. A., Sompallae, K., Bashir, A., Sompallae, R., Bossler, A. D., Jensen, C. S. & Ma, D. (2018). Simultaneous detection of single-nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA-based next-generation sequencing assay. Cancer Cytopathology 126 (3) 158-169. DOI: 10.1002/cncy.21963. PMID: 29364576.
  • da Ferreira Silva, R. C., Lieberman, S. M., Hoffman, H. T., Policeni, B., Bashir, A., Smith, R. J. & Sato, T. S. (2016). IgG4-related disease in an adolescent with radiologic-pathologic correlation. Radiol Case Rep 12 (1) 196-199. DOI: 10.1016/j.radcr.2016.10.008. PMID: 28228909. PMCID: PMC5310240.
  • Story MT, Sanders ML, Bashir AA, Longo JM, Abel SL, Dollard SC, Grodstein EI, Thomas CP, Katz DA. (2020). Infiltrating Kaposi sarcoma presenting as acute kidney injury: An unexpected consequence of deliberate hepatitis C-positive organ transplantation. Transpl Infect Dis. 2021 Apr;23(2):e13481. doi: 10.1111/tid.13481. Epub 2020 Oct 22. PMID: 33012057