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Bradley Ford, MD, PhD

Medical Director, Clinical Microbiology
Coordinator, Koontz Lecture Series
Program Director, Medical Microbiology Fellowship
Clinical Associate Professor of Pathology

Contact Information

Primary Office
C606-B General Hospital (GH)
Iowa City, IA 52242


PhD, Medical Scientist Training Program, Stony Brook University, Stony Brook, NY
MD, Medical Scientist Training Program, Stony Brook School of Medicine, Stony Brook, NY
Resident, Laboratory and Genomic Medicine, Barnes Jewish Hospital, St. Louis, MO
Fellow, Medical and Public Health Microbiology, Barnes Jewish Hospital, St. Louis, MO
Postdoctoral Fellow, Molecular Microbiology, Washington University, St. Louis, MO

Licensure and Certifications

State of Iowa Medical License - Iowa Board of Medicine
Diplomate in Clinical Pathology - American Board of Pathology

Research Summary

Dr. Ford's research focuses on development of new clinical testing methods using a variety of next generation platforms.


Humble, R. M., Merrill, A. E., Ford, B. A., Diekema, D. J. & Krasowski, M. D. (2021). Practical Considerations for Implementation of SARS-CoV-2 Serological Testing in the Clinical Laboratory: Experience at an Academic Medical Center. Acad Pathol, 8, 23742895211002802. PMID: 33889715.

Halvorson, T. S., Isaacson, A. L., Ford, B. A. & Firchau, D. J. (2020). The Postmortem Features of Mucormycosis. Acad Forensic Path, 10(2), 72-80. PMID: 33282040.

Hannah, C. E., Ford, B. A., Chung, J., Ince, D. & Wanat, K. A. (2020). Characteristics of Nontuberculous Mycobacterial Infections at a Midwestern Tertiary Hospital: A Retrospective Study of 365 Patients. Open forum infectious diseases, 7(6), ofaa173. PMID: 32587875.

Hodgson, C. K., Krasowski, M. D. & Ford, B. A. (2020). Data on the relationship of signal-to-cutoff ratio of two HIV antigen/antibody combination assays to subsequent confirmation of HIV-1 infection in a low-prevalence population. Data in brief, 31, 105707. PMID: 32462068.

Ford, B. A., McElvania, E. (2020). Machine Learning Takes Laboratory Automation to the Next Level. Journal of clinical microbiology. PMID: 32024725.

Kobayashi, T., Ford, B. & Sekar, P. (2019). Mycobacterium avium-intracellulare(MAI) liver abscess mimicking liver metastasis in a patient with rheumatoid arthritis on adalimumab and methotrexate. BMJ Case Reports, 12(6), e230912. DOI: 10.1136/bcr-2019-230912.

Krasowski, M. D., Lawrence, J. C., Briggs, A. S. & Ford, B. A. (2019). Burden and Characteristics of Unsolicited Emails from Medical/Scientific Journals, Conferences, and Webinars to Faculty and Trainees at an Academic Pathology Department. Journal of pathology informatics, 10, 16. PMID: 31149367.

Shields, B. E., Rosenbach, M., Brown-Joel, Z., Berger, A. P., Ford, B. A. & Wanat, K. A. (2019). Angioinvasive fungal infections impacting the skin: Background, epidemiology, and clinical presentation. Journal of the American Academy of Dermatology, 80(4), 869-880.e5. DOI: 10.1016/j.jaad.2018.04.059.

Berger, A. P., Ford, B. A., Brown-Joel, Z., Shields, B. E., Rosenbach, M. & Wanat, K. A. (2019). Angioinvasive fungal infections impacting the skin: Diagnosis, management, and complications. (Vols. 80). (4), pp. 883-898.e2. Journal of the American Academy of Dermatology. DOI: 10.1016/j.jaad.2018.04.058.

Canver, M. C., Gonzalez, M. D., Ford, B. A., Arnold, A. R., Lawhon, S. D., Burnham, C. D., Jenkins, S. G., Burd, E. M. & Westblade, L. F. (2019). Improved Performance of a Rapid Immunochromatographic Assay for Detection of PBP2a in Non-Staphylococcus aureus Staphylococcal Species. Journal of Clinical Microbiology, 57(4). DOI: 10.1128/jcm.01417-18.

Kobayashi, T., Ford, B. & Sekar, P. (2019). A case of severe cutaneous Mycobacterium marinum infection in a patient with Crohn’s disease on chronic high-dose prednisone. BMJ Case Reports, 12(1), bcr-2018-228516. DOI: 10.1136/bcr-2018-228516.

Chung, J., Ince, D., Ford, B. A. & Wanat, K. A. (2018). Cutaneous Infections Due to Nontuberculosis Mycobacterium: Recognition and Management. American journal of clinical dermatology. PMID: 30168084.

Beka, L., Fullmer, M. S., Colston, S. M., Nelson, M. C., Talagrand-Reboul, E., Walker, P., Ford, B., Whitaker, I. S., Lamy, B., Gogarten, J. P. & Graf, J. (2018). Low-Level Antimicrobials in the Medicinal Leech Select for Resistant Pathogens That Spread to Patients. mBio, 9(4). PMID: 30042201.

Marra, A. R., Edmond, M. B., Ford, B. A., Herwaldt, L. A., Algwizani, A. R. & Diekema, D. J. (2018). Impact of 2018 Changes in National Healthcare Safety Network Surveillance for Clostridium difficile Laboratory-Identified Event Reporting. Infection control and hospital epidemiology, 39(7), 886-888. PMID: 29708091.

Hoff, B. M., Ford, D. C., Ince, D., Ernst, E. J., Livorsi, D. J., Heintz, B. H., Masse, V., Brownlee, M. J. & Ford, B. A. (2018). Implementation of a Mobile Clinical Decision Support Application to Augment Local Antimicrobial Stewardship. Journal of pathology informatics, 9, 10. PMID: 29692947.

Ford, B. A. (2018). mecC-MRSA: Hiding in Plain Sight. Journal of clinical microbiology. PMID: 29118173.

Karkow, D., Ford, B., Hoff, B. & Ernst, E. (2017). Impact of an Antimicrobial Stewardship Bundle of Rapid Identification of Methicillin Susceptibility and Active Intervention on Treatment of Staphylococcus aureus Bacteremia. Open Forum Infectious Diseases, 4(suppl\_1), S495--S495. DOI: 10.1093/ofid/ofx163.1279.

Krasowski, M. D., Ford, B. A., Klutts, J. S., Jensen, C. S., Briggs, A. S., Robinson, R. A., Bruch, L. A. & Karandikar, N. J. (2017). Using Focused Laboratory Management and Quality Improvement Projects to Enhance Resident Training and Foster Scholarship. Academic pathology, 4, 2374289517722152. PMID: 28913416.

Ford, B., Kallstrom, G. (2017). The bioMérieux BacT/Alert: Automation at Last in the Black Box. Chapter 5,The Dark Art of Blood Cultures. W. Dunne, Jr , C. D. Burnham (Eds.) (1 edition) Washington, DC: ASM Press.

Flenker, K. S., Burghardt, E. L., Dutta, N., Burns, W. J., Grover, J. M., Kenkel, E. J., Weaver, T. M., Mills, J., Kim, H., Huang, L., Owczarzy, R., Musselman, C. A., Behlke, M. A., Ford, B. & McNamara, 2nd, J. O. (2017). Rapid Detection of Urinary Tract Infections via Bacterial Nuclease Activity. Molecular Therapy, 25(6), 1353-1362. PMID: 28391960.

Mathur, G., Yadav, K., Ford, B., Schafer, I., Basavaraju, S., Knust, B., Shieh, W., Hill, S., Locke, G., Quinlisk, P., Brown, S., Gibbons, A., Cannon, D., Kuehnert, M., Nichol, S., Rollin, P., Ströher, U. & Miller, R. (2017). High clinical suspicion of donor-derived disease leads to timely recognition and early intervention to treat solid organ transplant-transmitted lymphocytic choriomeningitis virus. Transplant Infectious Diseases, 4(19). PMID: 28423464.

Ford, B. (2017). Commentary on "Undetectable HDL Cholesterol in a Patient with Flu-Like Illness", Bock et al. Clinical chemistry, 63(3), 645-646. PMID: 28242833.

Dunseth, C. D., Ford, B. A. & Krasowski, M. D. (2017). Traditional versus reverse syphilis algorithms: A comparison at a large academic medical center. Practical Laboratory Medicine, 8(2017), 52-59. DOI: 10/1016/j.plabm.2017.04.007.

Marra, A. R., Edmond, M. B., Ford, B. A., Herwaldt, L. A., Algwizani, A. R. & Diekema, D. J. (2016). Failure of Risk-Adjustment by Test Method for C. difficile Laboratory-Identified Event Reporting. Infection control and hospital epidemiology, 1-3. PMID: 27745553.

Morriss, F. H., Lindower, J. B., Bartlett, H. L., Atkins, D. L., Kim, J. O., Klein, J. M. & Ford, B. A. (2016). Neonatal Enterovirus Infection: Case Series of Clinical Sepsis and Positive Cerebrospinal Fluid Polymerase Chain Reaction Test with Myocarditis and Cerebral White Matter Injury Complications. AJP reports, 6(3), e344-e351. PMID: 27695644.

Arnold, A. R., Burnham, C. A., Ford, B. A., Lawhon, S. D., McAllister, S. K., Lonsway, D., Albrecht, V., Jerris, R. C., Rasheed, J. K., Limbago, B., Burd, E. M. & Westblade, L. F. (2016). Evaluation of an Immunochromatographic Assay for Rapid Detection of Penicillin-Binding Protein 2a in Human and Animal Staphylococcus intermedius Group, Staphylococcus lugdunensis, and Staphylococcus schleiferi Clinical Isolates. Journal of clinical microbiology, 54(3), 745-8. PMID: 26677248.

Falcone, E. L., Petts, J. R., Fasano, M. B., Ford, B., Nauseef, W. M., Neves, J. F., Simões, M. J., Tierce, 4th, M. L., de la Morena, M. T., Greenberg, D. E., Zerbe, C. S., Zelazny, A. M. & Holland, S. M. (2016). Methylotroph Infections and Chronic Granulomatous Disease. Emerging infectious diseases, 22(3), 404-9. PMID: 26886412.

Jarvis, C., Han, Z., Kalas, V., Klein, R., Pinkner, J. S., Ford, B., Binkley, J., Cusumano, C. K., Cusumano, Z., Mydock-McGrane, L., Hultgren, S. J. & Janetka, J. W. (2016). Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. ChemMedChem, 11(4), 367-73. PMID: 26812660.

Ford, B. A. (2016). Identification of low-level vancomycin resistance in Staphylococcus aureus in the era of informatics. Journal of clinical microbiology. PMID: 26865694.

Krasowski, M. D., Wilford, J. D., Howard, W., Dane, S. K., Davis, S. R., Karandikar, N. J., Blau, J. L. & Ford, B. A. (2016). Implementation of Epic Beaker Clinical Pathology at an academic medical center. Journal of pathology informatics, 7, 7. PMID: 26955505.

Burghardt, E. L., Flenker, K. S., Clark, K. C., Miguel, J., Ince, D., Winokur, P., Ford, B. & McNamara, 2nd, J. O. (2016). Rapid, Culture-Free Detection of Staphylococcus aureus Bacteremia. PloS one, 11(6), e0157234. PMID: 27305148.

Ford, B. R., Schlueter, A. (2016). Culture of Blood and Cellular Therapy Products in Blood Banking. In A. L. Leber (Eds.) Clinical Microbiology Procedures Handbook. (4), pp. Sterling, VA: American Society for Microbiology Press. DOI: 10.1128/9781555818814.ch13.3.

Ogrin, C., Ford, B. A., Stauffer, S. L., Krasowski, M. D. & Azar, A. E. (2015). Positive test for anti-thyroglobulin antibodies due to administration of immunoglobulin replacement therapy in a patient with thyroid cancer. Endocrine Practice. PMID: 26151422.

Westblade, L. F., Ranganath, S., Dunne, Jr., W. M., Burnham, C. D., Fader, R. & Ford, B. A. (2015). Infection with a chlorophyllic eukaryote after a traumatic freshwater injury. N Engl J Med, 372(10), 982-4. PMID: 25738686.

Krasowski, M. D., Schriever, A., Mathur, G., Blau, J. L., Stauffer, S. L. & Ford, B. A. (2015). Use of a data warehouse at an academic medical center for clinical pathology quality improvement, education, and research. Journal of pathology informatics, 6, 45. PMID: 26284156.

Westblade, L. F., Shams, F., Duong, S., Tariq, O., Bulbin, A., Klirsfeld, D., Sakaria, S., Ford, B. A., Burnham, C. D. & Ginocchio, C. D. (2014). Septic arthritis of a native knee joint due to corynebacterium striatum. J Clin Microbiol, JCM.02641-13. PMID: 24574280.

El-Herte, R. I., Schouweiler, K. E., Farah, R. S., Arbulu, R., Diekema, D. J., Wanat, K. A. & Ford, B. A. (2014). Phaeoacremonium parasiticum phaeohyphomycosis in a patient with systemic lupus erythematosus treated successfully with surgical debridement and voriconazole: A case report and review of the literature. IDCases, 1(4), 84-88. DOI: doi:10.1016/j.idcr.2014.10.004.

Storm, J. C., Ford, B. A. & Streit, J. A. (2013). Myocardial infection due to Fusobacterium necleatum. Diagn Microbiol Infec Dis, 77(4), 373-5. PMID: 24094834.

Demarco, M. L., Ford, B. A. (2013). Beyond identification: emerging and future uses for MALDI-TOF mass spectrometry in the clinical microbiology laboratory. Clin Lab Med, 33(3), 611-628. PMID: 23931841.

Pence, M. A., Sharon, J., Tekippe, M., Pakalniskis, B. L., Ford, B. & Burnham, C. D. (2013). Two cases of Kerstersia gyiorum isolated from sites of chronic infection. Journal of Clinical Microbiology, 51(6), 2001-04. PMID: 23596236.

Ford, B., Burnham, C. A. (2013). Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper. Journal of clinical microbiology, 51(5), 1412-20. PMID: 23426923.

Brosnahan, A. J., Merriman, J. A., Salgado-Pabón, W., Ford, B. & Schlievert, P. M. (2013). Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal epithelial cells through tetramic acids. PLosONE, 8(4), e61255. PMID: 23613823.

Guiton, P. S., Hannan, T. J., Ford, B., Caparon, M. G. & Hultgren, S. J. (2013). Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urirnary tract infections. Infection and immunity, 81(1), 329-39. PMID: 23132492.

Ford, B., Verger, D., Dodson, K., Volkan, E., Kostakioti, M., Elam, J., Pinkner, J., Waksman, G. & Hultgren, S. (2012). Structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket. Journal of bacteriology, 194(23), 6390-7. PMID: 23002225.

Dunne, W. M., Westblade, L. F. & Ford, B. (2012). Next-generation and whole-genome sequencing in the diagnostic clinical microbiology laboratory. European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology, 31(8), 1719-26. PMID: 22678348.

Volkan, E., Ford, B., Pinkner, J. S., Dodson, K. W., Henderson, N. S., Thanassi, D. G., Waksman, G. & Hultgren, S. J. (2012). Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine. Proceedings of the National Academy of Sciences of the United States of America, 109(24), 9563-8. PMID: 22645361.

Han, Z., Pinkner, J. S., Ford, B., Chorell, E., Crowley, J. M., Cusumano, C. K., Campbell, S., Henderson, J. P., Hultgren, S. J. & Janetka, J. W. (2012). Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. Journal of medicinal chemistry, 55(8), 3945-59. PMID: 22449031.

Shu, Q., Crick, S. L., Pinkner, J. S., Ford, B., Hultgren, S. J. & Frieden, C. (2012). The E. coli CsgB nucleator of curli assembles to ß-sheet oligomers that alter the CsgA fibrillization mechanism. Proceedings of the National Academy of Sciences of the United States of America, 109(17), 6502-7. PMID: 22493266.

Cusumano, C. K., Pinkner, J. S., Han, Z., Greene, S. E., Ford, B., Crowley, J. R., Henderson, J. P., Janetka, J. W. & Hultgren, S. J. (2011). Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Science translational medicine, 3(109), 109. PMID: 22089451.

Phan, G., Remaut, H., Wang, T., Allen, W. J., Pirker, K. F., Lebedev, A., Henderson, N. S., Geibel, S., Volkan, E., Yan, J., Kunze, M. B., Pinkner, J. S., Ford, B., Kay, C. W., Li, H., Hultgren, S. J., Thanassi, D. G. & Waksman, G. (2011). Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature, 474(7349), 49-53. PMID: 21637253.

Ford, B., Eby, C. S., Scott, M. G. & Coyne, D. W. (2010). Intra-individual variability in serum hepcidin precludes its use as a marker of iron status in hemodialysis patients. Kidney international, 78(8), 769-73. PMID: 20668427.

Ford, B., Han, Z., Pinkner, J. S., Obermann, R., Nolan, W., Wildman, S. A., Hobbs, D., Ellenberger, T., Cusumano, C. K., Hultgren, S. J. & Janetka, J. W. (2010). Structure-based drug design and optimization of mannoside bacterial FimH antagonists. Journal of medicinal chemistry, 53(12), 4779-92. PMID: 20507142.

Ford, B., Rêgo, A. T., Ragan, T. J., Pinkner, J., Dodson, K., Driscoll, P. C., Hultgren, S. & Waksman, G. (2010). Structural homology between the C-terminal domain of the PapC usher and its plug. Journal of bacteriology, 192(7), 1824-31. PMID: 20118254.

Ford, B., Boykevisch, S., Zhao, C., Kunzelmann, S., Bar-Sagi, D., Herrmann, C. & Nassar, N. (2009). Characterization of a Ras mutant with identical GDP- and GTP-bound structures. Biochemistry, 48(48), 11449-57. PMID: 19883123.

Klutts, J. S., Ford, B., Perez, N. R. & Gronowski, A. M. (2009). Evidence-based approach for interpretation of Epstein-Barr virus serological patterns. Journal of clinical microbiology, 47(10), 3204-10. PMID: 19656988.

Ford, B., Coyne, D. W., Eby, C. S. & Scott, M. G. (2009). Variability of ferritin measurements in chronic kidney disease; implications for iron management. Kidney international, 75(1), 104-10. PMID: 18843257.

Ferguson, A. M., Ford, B. & Gronowski, A. M. (2008). Method validation for cerebral spinal fluid human chorionic gonadotropin measurement with the Advia Centaur. Clinical chemistry, 54(8), 1408-9. PMID: 18664453.

Mikhailik, A., Ford, B., Keller, J., Chen, Y., Nassar, N. & Carpino, N. (2007). A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling. Molecular cell, 27(3), 486-97. PMID: 17679096.

Kleinman, H., Ford, B., Keller, J., Carpino, N. & Nassar, N. (2006). Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1. Acta crystallographica - Section F, Structural biology and crystallization communications, 62(Pt 3), 218-20. PMID: 16511305.

Ford, B., Hornak, V., Kleinman, H. & Nassar, N. (2006). Structure of a transient intermediate for GTP hydrolysis by ras. Structure (London, England : 1993), 14(3), 427-36. PMID: 16531227.

Ford, B., Skowronek, K., Boykevisch, S., Bar-Sagi, D. & Nassar, N. (2005). Structure of the G60A mutant of RAS: implications for the dominant negative effect. The Journal of biological chemistry, 280(27), 25697-705. PMID: 15878843.