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Deqin Ma, MD, PhD

Clinical Professor of Pathology

Introduction

My research interest is primarily focused on developing molecular oncology tests and their application in the study of tumor/metastatic suppressors.

Current Positions

  • Clinical Professor of Pathology
  • Medial Director, Molecular Pathology Laboratory, Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA
  • Program Director, Molecular Genetic Fellowship, Pathology

Education

  • MD, Shandong Medical University, Jinan, P.R. China
  • MS in Biochemistry, Shandong Medical University, Jinan, P.R. China
  • PhD in Biochemistry, University of Kentucky Medical Center, Lexington, KY
  • Postdoctoral Fellow in Hematology/Oncology, University of Kentucky Medical Center, Department of Pediatrics, Lexington, Kentucky
  • Resident in Anatomic Pathology, National Cancer Institute/National Institutes of Health, Bethesda, MD
  • Fellow in Molecular Genetic Pathology, M.D. Anderson Cancer Center, University of Texas, Houston, TX
  • Fellow in Surgical Pathology, Hospital of the University of Pennsylvania, Philadelphia, PA

Research Interests

  • Correlation between PTEN expression and KIT mutation in GIST
  • KIT mutation analysis in pediatric solitary mastocytoma

Licenses & Certifications

  • State of Iowa Medical License, Iowa Board of Medicine, Iowa
  • Diplomat, Molecular Genetic Pathology, American Board of Pathology
  • Diplomat, Anatomic Pathology, American Board of Pathology

Selected Publications

  • Dundar B, Alsawas M, Masaadeh A, Conway K, Snow AN, Sompallae RR, Bossler AD, Ma D, Lopes Abath Neto O. (2024) Molecular characterization and survival analysis of a cohort of glioblastoma, IDH-wildtype. Pathol Res Pract. May; 257:155272. DOI: 10.1016/j.prp.2024.155272. PMID: 38631135.
  • Benhamida JK, Harmsen HJ, Ma D, William CM, Li BK, Villafania L, Sukhadia P, Mullaney KA, Dewan MC, Vakiani E, Karajannis MA, Snuderl M, Zagzag D, Ladanyi M, Rosenblum MK, Bale TA. (2023) Recurrent TRAK1::RAF1 Fusions in pediatric low-grade gliomas. Sep; 33(5):e13185. DOI: 10.1111/bpa.13185. PMID: 37399073. PMCID: PMC10467040.
  • Sompallae RR, Dundar B, Guseva NV, Bossler AD, Ma D. (2023) EGFR and ERBB2 exon 20 insertion/duplication in advanced non-small cell lung cancer: genomic profiling and clinicopathologic features. Front Oncol. Mayy 22; 13:1163485. DOI: 10.3389/fonc.2023.1163485. PMID: 37284196. PMCID: PMC10239961.
  • West, J. M., Ma, D., Mott, S. L. & Brown, J. A. (2020). Cell cycle progression score has potential prognostic value for stage T1 renal cell carcinomas. Urologic oncology. DOI: 10.1016/j.urolonc.2019.12.025. PMID: 32081562.
  • Alzubaidi, A. N., Nepple, K. G., Vollstedt, A., Dahmoush, L., Ma, D., Henry, M. D. & Brown, J. A. (2019). Alpha-dystroglycan staining pattern and mortality in patients undergoing radical prostatectomy with lymph node positive prostate cancer. The Canadian journal of urology 26 (6) 10054-10060. PMID: 31860423.
  • Yu, Y. P., Liu, P., Nelson, J., Hamilton, R. L., Bhargava, R., Michalopoulos, G., Chen, Q., Zhang, J., Ma, D., Pennathur, A., Luketich, J., Nalesnik, M., Tseng, G. & Luo, J. H. (2019). Identification of recurrent fusion genes across multiple cancer types. Scientific reports 9 (1) 1074. DOI: 10.1038/s41598-019-38550-6. PMID: 30705370. PMCID: PMC6355770.
  • Isaacson, A. L., Guseva, N. V., Bossler, A. D. & Ma, D. (2019). Urothelial carcinoma with an NRF1-BRAF rearrangement and response to targeted therapy. Cold Spring Harbor Molecular Case Studies 5 (3). DOI: 10.1101/mcs.a003848.
  • Swami, U., Ma, D. & Zhang, J. (2018). Response to Erlotinib in a Patient with Compound EGFR L747S and Exon 19 Deletion. (Vols. 13). (7), pp. e129-e130. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. DOI: 10.1016/j.jtho.2018.03.034. PMID: 29935854.
  • Sande, C. M., Chang, B., Monga, V., Bossler, A. D. & Ma, D. (2018). Biallelic TP53 gain of function mutations in rapidly progressing solid tumors. Cancer genetics 222-223 20-24. DOI: 10.1016/j.cancergen.2018.02.001. PMID: 29666004.
  • Guseva, N. V., Jaber, O., Stence, A. A., Sompallae, K., Bashir, A., Sompallae, R., Bossler, A. D., Jensen, C. S. & Ma, D. (2018). Simultaneous detection of single-nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA-based next-generation sequencing assay. Cancer cytopathology. DOI: 10.1002/cncy.21963. PMID: 29364576.