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Nitin Karandikar, MD, PhD

Professor of Pathology

Current Positions

  • Professor of Pathology
  • Chair and Department Executive Officer, Pathology
  • Dr. Richard G. Lynch Chair in Experimental Pathology

Education

  • MBBS in Bachelor of Medicine and Surgery, B.J. Medical College, University of Poona, Pune, India
  • MD in Pathology, B.J. Medical College, University of Poona, Pune, India
  • PhD in Immunology and Molecular Pathogenesis Graduate Program, Northwestern University Medical School, Chicago, Illinois
  • Internship, B.J. Medical College, University of Poona, Pune, India
  • Resident in Anatomic and Clinical Pathology, B.J. Medical College, University of Poona, Pune, India
  • Resident in Clinical Pathology, University of Texas Southwestern Medical Center, Dallas, Dallas, Texas
  • Fellow in Hematopathology, University of Texas Southwestern Medical Center, Dallas, Dallas, Texas
  • Postdoctoral Fellow in Research in Immunology, University of Texas Southwestern Medical Center, Dallas, Texas

Graduate Program Affiliations

Research Interests

  • Area of Research

Licenses & Certifications

  • State of Iowa Medical License, Iowa Board of Medicine, Iowa
  • Hematology, American Board of Pathology
  • State of Texas Medical License, Texas Board of Medicine, Texas
  • Clinical Pathology, American Board of Pathology

Selected Publications

  • Vemulawada C, Renavikar PS, Crawford MP, Steward-Tharp S, Karandikar NJ. (2024) Disruption of IFN-gamma, GZMB, PRF1, or YST Results in Reduced Suppressive Function in Human CD8+ T Cells. J. Immunol. Jun 1; 212(11):1722-1732. DOI: 10.4049/jimmunol.2300388. PMID: 38607279. PMCID: PMC11105984.
  • Wilhelm CR, Upadhye MA, Eschbacher KL, Karandikar NJ, Boyden AW. (2023) Proteolipid Protein-Induced Mouse Model of Multiple Sclerosis Requires B Cell-Mediated Antigen Presentation. J Immunol. Sep 15; 211(6):944-953. DOI: 10.4049/jimmunol.2200721. PMID: 37548478. PMCID: PMC10528642.
  • Brate, A. A., Boyden, A. W., Jensen, I. J., Badovinac, V. P. & Karandikar, N. J. (2021). A Functionally Distinct CXCR3+/IFN-γ+/IL-10+ Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells. J immunol. DOI: 10.4049/jimmunol.2001143. PMID: 33558376.
  • Chopra, S., Dunham, T., Syrbu, S. I., Karandikar, N. J., Darbro, B. W. & Holman, C. J. (2021). Utility of Flow Cytometry and Fluorescence In Situ Hybridization in Follow-up Monitoring of Plasma Cell Myeloma. Am J Clin Pathol. DOI: 10.1093/ajcp/aqaa224. PMID: 33437993.
  • Crawford, M. P., Sinha, S., Renavikar, P. S., Borcherding, N. & Karandikar, N. J. (2020). CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression. Proceedings of the National Academy of Sciences of the United States of America. DOI: 10.1073/pnas.2005010117. PMID: 32719138.
  • Roa, J. A., Sarkar, D., Zanaty, M., Ishii, D., Lu, Y., Karandikar, N. J., Hasan, D. M., Ortega, S. B. & Samaniego, E. A. (2020). Preliminary results in the analysis of the immune response after aneurysmal subarachnoid hemorrhage. Scientific reports 10 (1) 11809. DOI: 10.1038/s41598-020-68861-y. PMID: 32678268.
  • Boyden, A. W., Brate, A. A., Stephens, L. M. & Karandikar, N. J. (2020). Immune Autoregulatory CD8 T Cells Require IFN-γ Responsiveness to Optimally Suppress Central Nervous System Autoimmunity. Journal of immunology (Baltimore, Md. : 1950). DOI: 10.4049/jimmunol.2000211. PMID: 32532836.
  • Boyden, A. W., Brate, A. A. & Karandikar, N. J. (2020). Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein. Scientific reports 10 (1) 5011. DOI: 10.1038/s41598-020-61928-w. PMID: 32193439. PMCID: PMC7081236.
  • Shahi, S. K., Freedman, S. N., Dahl, R. A., Karandikar, N. J. & Mangalam, A. K. (2019). Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system. Scientific reports 9 (1) 19194. DOI: 10.1038/s41598-019-55713-7. PMID: 31844134. PMCID: PMC6915774.