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Osorio Lopes Abath Neto, MD, PhD

Clinical Assistant Professor of Pathology

Current Positions

  • Clinical Assistant Professor - Pathology

Education

  • PhD, Neurology, Universidade de Sao Paulo, Sao Paulo, Brazil
  • MD, Universidade Federal da Paraiba, Joao Pessoa, Brazil
  • MS, Computer Science, Universidade Federal de Campina Grande, Campina Grande, Brazil
  • BS, Computer Science, Universidade Federal da Paraiba, Campina Grande, Brazil
  • Anatomic Pathology, National Cancer Institute/National Institutes of Health, Bethesda, Md.
  • Neurology, Santa Marcelina Hospital, Sao Paulo, Brazil
  • Neuropathology, University of Pittsburgh Medical Center, Pittsburgh

Research Interests

  • Brain Tumors
  • Motor neuron disease
  • Neurological disorders
  • Neuromuscular disorders
  • Neuropathies
  • Pediatric brain tumors
  • Pediatric spinal cord tumors

Licenses & Certifications

  • Anatomic Pathology, American Board of Pathology

Selected Publications

  • Dundar B, Alsawas M, Masaadeh A, Conway K, Snow AN, Sompallae RR, Bossler AD, Ma D, Lopes Abath Neto O. (2024) Molecular characterization and survival analysis of a cohort of glioblastoma, IDH-wildtype. Pathol Res Pract. May; 257:155272. DOI: 10.1016/j.prp.2024.155272. PMID: 38631135.
  • Lopes Abath Neto, O., Bale, T. A., Benhamida, J., Mata, D., Turakulov, R., Abdullaev, Z., Marker, D., Ketchum, C., Chung, H. J., Giannini, C., Quezado, M., Pratt, D., Aldape, K. & Wu, Z. (2022). DNA methylation analysis of glioblastomas harboring FGFR3-TACC3 fusions identifies a methylation subclass with better patient survival. Acta neuropathologica 144 (1) 155-157. PMID: 35567606. DOI: 10.1007/s00401-022-02430-7.
  • Lopes Abath Neto, O., Medne, L., Donkervoort, S., Rodríguez-García, M. E., Bolduc, V., Hu, Y., Guadagnin, E., Foley, A. R., Brandsema, J. F., Glanzman, A. M., Tennekoon, G. I., Santi, M., Berger, J. H., Megeney, L. A., Komaki, H., Inoue, M., Cotrina-Vinagre, F. J., Hernández-Lain, A., Martin-Hernández, E., Williams, L., Borell, S., Schorling, D., Lin, K., Kolokotronis, K., Lichter-Konecki, U., Kirschner, J., Nishino, I., Banwell, B., Martínez-Azorín, F., Burgon, P. G. & Bönnemann, C. G. (2021). MLIP causes recessive myopathy with rhabdomyolysis, myalgia and baseline elevated  serum creatine kinase. Brain : a journal of neurology 144 (9) 2722-2731. DOI: 10.1093/brain/awab275. PMID: 34581780. PMCID: PMC8536936.
  • Lopes Abath Neto, O. & Aldape, K. (2021). Morphologic and Molecular Aspects of Glioblastomas. Neurosurgery clinics of North America 32 (2) 149-158. DOI: 10.1016/j.nec.2021.01.001. PMID: 33781498.
  • Chrast, R., Strom, T. M., Kamsteeg, E. J., Bönnemann, C. G., Gleeson, J. G., Martini, R., Janke, C., Senderek, J., Shashi, V., Magiera, M. M., Klein, D., Zaki, M., Schoch, K., Rudnik-Schöneborn, S., Norman, A., Lopes Abath Neto, O., Dusl, M., Yuan, X., Bartesaghi, L., De Marco, P., Alfares, A. A., Marom, R., Arold, S. T., Guzmán-Vega, F. J., Pena, L. D., Smith, E. C., Steinlin, M., Babiker, M. O., Mohassel, P., Foley, A. R., Donkervoort, S., Kaur, R., Ghosh, P. S., Stanley, V., Musaev, D., Nava, C., Mignot, C., Keren, B., Scala, M., Tassano, E., Picco, P., Doneda, P., Fiorillo, C., Issa, M. Y., Alassiri, A., Alahmad, A., Gerard, A., Liu, P., Yang, Y., Ertl-Wagner, B., Kranz, P. G., Wentzensen, I. M., Stucka, R., Stong, N., Allen, A. S., Goldstein, D. B., Schoser, B., Rösler, K. M., Alfadhel, M. & Capra, V. (2018). Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration. The EMBO journal 37 (23). PMID: 30420557. DOI: 10.15252/embj.2018100540.
  • Abath Neto O, Moreno CAM, Malfatti E, Donkervoort S, Böhm J, Guimarães JB, Foley AR, Mohassel P, Dastgir J, Bharucha-Goebel DX, Monges S, Lubieniecki F, Collins J, Medne L, Santi M, Yum S, Banwell B, Salort-Campana E, Rendu J, Fauré J, Yis U, Eymard B, Cheraud C, Schneider R, Thompson J, Lornage X, Mesrob L, Lechner D, Boland A, Deleuze JF, Reed UC, Oliveira ASB, Biancalana V, Romero NB, Bönnemann CG, Laporte J, Zanoteli E. Common and variable clinical, histological, and imaging findings of recessive RYR1-related centronuclear myopathy patients. Neuromuscul Disord 2017; 27(11):975-985. PMID: 28818389; doi: 10.1016/j.nmd.2017.05.016.
  • Abath Neto O, Silva MR, Martins Cde A, Oliveira Ade S, Reed UC, Biancalana V, Pesquero JB, Laporte J, Zanoteli E. A Study of a Cohort of X-Linked Myotubular Myopathy at the Clinical, Histologic, and Genetic Levels. Pediatr Neurol 2016; 58:107-12. PMID: 26995067; doi: 10.106/j.pediatrneurol.2016.01.023.
  • Abath Neto O, Tassy O, Biancalana V, Zanoteli E, Pourquié O, Laporte J. Integrative data mining highlights candidate genes for monogenic myopathies. PLoS One. 2014; 9(10):e110888. PMID: 25353622; doi: 10.1371/journal.pone.0110888.
  • Lopes Abath Neto, O., Koretz, Z. A., Wald, A. I., Rath, P. P., Nikiforova, M. & Chu, C. T. (2022). Molecular profiling of renal cell carcinoma presenting as iris metastasis. (Vols. 27). pp. 101599. American journal of ophthalmology case reports. DOI: 10.1016/j.ajoc.2022.101599. PMID: 35664447. PMCID: PMC9157370.
  • Raffeld, M., Abdullaev, Z., Pack, S. D., Xi, L., Nagaraj, S., Briceno, N., Vera, E., Pittaluga, S., Lopes Abath Neto, O., Quezado, M., Aldape, K., Armstrong, T. S. & Gilbert, M. R. (2020). High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma. Acta neuropathologica communications 8 (1) 101. DOI: 10.1186/s40478-020-00973-y. PMID: 32641156. PMCID: PMC7346356.