Aliye Uc, MD

Portrait
Division Director
Professor of Pediatrics - Gastroenterology
Professor of Radiation Oncology

Contact Information

Primary Office
1120-C Boyd Tower
200 Hawkins Drive
Iowa City, IA 52242
319-356-2950

Education

MD, Medicine, Istanbul University School of Medicine
Resident, Pediatrics, Hacettepe University Children's Hospital
Resident, PL3, Pediatrics, University of Iowa Hospitals and Clinics
Fellow, Pediatric Gastroenterology, University of Iowa Children's Hospital

Licensure and Certifications

FLEX
FMGEMS
Board Certification in Pediatrics, Turkey
Turkey Permanent Medical License

Education/Training Program Affiliations

Free Radical and Radiation Biology Graduate Program

Center, Program and Institute Affiliations

Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases

Research Summary

Dr. Uc is a Pediatric Gastroenterologist with clinical and research focus in Cystic Fibrosis (CF)-related pancreatic disease, and acute and chronic pancreatitis in children. Her laboratory focuses on dissecting the mechanisms of pancreatic damage and inflammation in CF pigs and development of gene therapies to the pig pancreas. She described that the CF pigs had an increased immune and inflammatory response in their pancreas that could be responsible of ongoing injury. She coauthored publications with Dr. Michael Welsh’s group describing the phenotype of CF pig model. She is collaborating with Drs. Engelhardt and Norris on better understanding the pathogenesis of CF-related diabetes (CFRD) using the CF pig and ferret models. She is also the chair and the founding member of INSPPIRE (International Study Group of Pediatric Pancreatitis: In search for a cure) with the task of studying the epidemiology, etiology, natural history and outcomes of pediatric pancreatitis, a disease without clear diagnostic parameters and treatment alternatives in children. In this context, she is developing a data registry, sample repository, and longitudinal studies on pediatric pancreatitis. University of Iowa is the coordinating center for this NIH-funded multicenter study with 14 other centers providing patients, data and biological samples. This constitutes the first initiative to create a multi-center approach to systematically characterize pancreatitis in children.

Publications

Sun, X., Yi, Y., Liang, B., Yang, Y., He, N., Ode, K. L., Uc, A., Wang, K., Gibson-Corley, K. N., Engelhardt, J. F. & Norris, A. W. (2019). Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. PMID: 30738804.

Uc, A., Husain, S. Z. (2019). Pancreatitis in Children. Gastroenterology. PMID: 30716320.

Norris, A. W., Uc, A. (2018). A Novel Stomach-Pancreas Connection: More than Physical. EBioMedicine, 37, 25-26. PMID: 30314893.

Uc, A., Andersen, D. K., Borowitz, D., Glesby, M. J., Mayerle, J., Sutton, R. & Pandol, S. J. (2018). Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis-Knowledge Gaps and Research Opportunities: Overview Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas, 47(10), 1180-1184. PMID: 30325855.

Abu-El-Haija, M., Gukovskaya, A. S., Andersen, D. K., Gardner, T. B., Hegyi, P., Pandol, S. J., Papachristou, G. I., Saluja, A. K., Singh, V. K., Uc, A. & Wu, B. U. (2018). Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Acute Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas, 47(10), 1185-1192. PMID: 30325856.

Forsmark, C. E., Andersen, D. K., Farrar, J. T., Golden, M., Habtezion, A., Husain, S. Z., Li, L., Mayerle, J., Pandol, S. J., Uc, A., Zhu, Z. & Yadav, D. (2018). Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Chronic Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas, 47(10), 1200-1207. PMID: 30325858.

Lowe, M. E., Goodman, M. T., Coté, G. A., Glesby, M. J., Haupt, M., Schork, N. J., Singh, V. K., Andersen, D. K., Pandol, S. J., Uc, A. & Whitcomb, D. C. (2018). Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Recurrent Acute Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas, 47(10), 1193-1199. PMID: 30325857.

Uc, A., Perito, E. R., Pohl, J. F., Shah, U., Abu-El-Haija, M., Barth, B., Bellin, M. D., Ellery, K. M., Fishman, D. S., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R. W., Husain, S. Z., Maqbool, A., Mascarenhas, M. R., McFerron, B. A., Morinville, V. D., Lin, T. K., Liu, Q. Y., Nathan, J. D., Rhee, S. J., Ooi, C. Y., Sellers, Z. M., Schwarzenberg, S. J., Serrano, J., Troendle, D. M., Werlin, S. L., Wilschanski, M., Zheng, Y., Yuan, Y. & Lowe, M. E. (2018). INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort Study: Design and Rationale for INSPPIRE 2 From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas, 47(10), 1222-1228. PMID: 30325861.

Fisher, W. E., Cruz-Monserrate, Z., McElhany, A. L., Lesinski, G. B., Hart, P. A., Ghosh, R., Van Buren, G., Fishman, D. S., Rinaudo JAS,, Serrano, J., Srivastava, S., Mace, T., Topazian, M., Feng, Z., Yadav, D., Pandol, S. J., Hughes, S. J., Liu, R. Y., Lu, E., Orr, R., Whitcomb, D. C., Abouhamze, A. S., Steen, H., Sellers, Z. M., Troendle, D. M., Uc, A., Lowe, M. E. & Conwell, D. L. (2018). Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas, 47(10), 1213-1221. PMID: 30325860.

Uc, A., Zimmerman, M. B., Wilschanski, M., Werlin, S. L., Troendle, D., Shah, U., Schwarzenberg, S. J., Rhee, S., Pohl, J. F., Perito, E. R., Palermo, J. J., Ooi, C. Y., Liu, Q., Lin, T. K., Morinville, V. D., McFerron, B. A., Husain, S. Z., Himes, R., Heyman, M. B., Gonska, T., Giefer, M. J., Gariepy, C. E., Freedman, S. D., Fishman, D. S., Bellin, M. D., Barth, B., Abu-El-Haija, M. & Lowe, M. E. (2018). Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis. Pancreas, 47(8), 967-973. PMID: 30059474.

Scheers, I., Palermo, J. J., Freedman, S., Wilschanski, M., Shah, U., Abu-El-Haija, M., Barth, B., Fishman, D. S., Gariepy, C., Giefer, M. J., Heyman, M. B., Himes, R. W., Husain, S. Z., Lin, T. K., Liu, Q., Lowe, M., Mascarenhas, M., Morinville, V., Ooi, C. Y., Perito, E. R., Piccoli, D. A., Pohl, J. F., Schwarzenberg, S. J., Troendle, D., Werlin, S., Zimmerman, B., Uc, A. & Gonska, T. (2018). Recommendations for Diagnosis and Management of Autoimmune Pancreatitis in Childhood: Consensus From INSPPIRE. Journal of pediatric gastroenterology and nutrition, 67(2), 232-236. PMID: 29746340.

O'Malley, Y., Rotti, P. G., Thornell, I. M., Vanegas Calderón, O. G., Febres-Aldana, C., Durham, K., Yao, J., Li, X., Zhu, Z., Norris, A. W., Zabner, J., Engelhardt, J. F. & Uc, A. (2018). Development of a polarized pancreatic ductular cell epithelium for physiological studies. Journal of applied physiology (Bethesda, Md. : 1985), 125(1), 97-106. PMID: 29517421.

Abu-El-Haija, M., Uc, A., Werlin, S. L., Freeman, A. J., Georgieva, M., Jojkic-Pavkov, D., Kalnins, D., Kochavi, B., Koot BGP,, Van Biervliet, S., Walkowiak, J., Wilschanski, M. & Morinville, V. D. (2018). Nutritional Considerations in Pediatric Pancreatitis: A Position Paper from the NASPHAN Pancreas Committee and ESPHAN Cystic Fibrosis/Pancreas Working Group. Journal of pediatric gastroenterology and nutrition, 67(1), 131-143. PMID: 29927872.

Guda, N. M., Muddana, V., Whitcomb, D. C., Levy, P., Garg, P., Cote, G., Uc, A., Varadarajulu, S., Vege, S. S., Chari, S. T., Forsmark, C. E., Yadav, D., Reddy, D. N., Tenner, S., Johnson, C. D., Akisik, F., Saluja, A. K., Lerch, M. M., Mallery, J. S. & Freeman, M. L. (2018). Recurrent Acute Pancreatitis: International State-of-the-Science Conference With Recommendations. Pancreas, 47(6), 653-666. PMID: 29894415.

Lin, T. K., Abu-El-Haija, M., Nathan, J. D., Palermo, J. P., Barth, B., Bellin, M., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Husain, S. Z., Liu, Q., Maqbool, A., Mascarenhas, M., McFerron, B., Morinville, V. D., Ooi, C. Y., Perito, E., Pohl, J. F., Rhee, S., Schwarzenberg, S. J., Shah, U., Troendle, D., Werlin, S. L., Wilschanski, M., Zimmerman, M. B., Lowe, M. E. & Uc, A. (2018). Pancreas Divisum in Pediatric Acute Recurrent and Chronic Pancreatitis: Report From INSPPIRE. Journal of clinical gastroenterology. PMID: 29864067.

Rotti, P. G., Xie, W., Poudel, A., Yi, Y., Sun, X., Tyler, S. R., Uc, A., Norris, A. W., Hara, M., Engelhardt, J. F. & Gibson-Corley, K. N. (2018). Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets. The American journal of pathology, 188(4), 876-890. PMID: 29366680.

Párniczky, A., Abu-El-Haija, M., Husain, S., Lowe, M., Oracz, G., Sahin-Tóth, M., Szabó, F. K., Uc, A., Wilschanski, M., Witt, H., Czakó, L., Grammatikopoulos, T., Rasmussen, I. C., Sutton, R. & Hegyi, P. (2018). EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 18(2), 146-160. PMID: 29398347.

Abu-El-Haija, M., Kumar, S., Quiros, J. A., Balakrishnan, K., Barth, B., Bitton, S., Eisses, J. F., Foglio, E. J., Fox, V., Francis, D., Freeman, A. J., Gonska, T., Grover, A. S., Husain, S. Z., Kumar, R., Lapsia, S., Lin, T., Liu, Q. Y., Maqbool, A., Sellers, Z. M., Szabo, F., Uc, A., Werlin, S. L. & Morinville, V. D. (2018). Management of Acute Pancreatitis in the Pediatric Population: A Clinical Report From the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Pancreas Committee. Journal of pediatric gastroenterology and nutrition, 66(1), 159-176. PMID: 29280782.

Scheers, I., Palermo, J. J., Freedman, S., Wilschanski, M., Shah, U., Abu-El-Haija, M., Barth, B., Fishman, D. S., Gariepy, C., Giefer, M. J., Heyman, M. B., Himes, R. W., Husain, S. Z., Lin, T. K., Liu, Q., Lowe, M., Mascarenhas, M., Morinville, V., Ooi, C. Y., Perito, E. R., Piccoli, D. A., Pohl, J. F., Schwarzenberg, S. J., Troendle, D., Werlin, S., Zimmerman, B., Uc, A. & Gonska, T. (2017). Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management. The American journal of gastroenterology, 112(10), 1604-1611. PMID: 28374818.

Sun, X., Yi, Y., Xie, W., Liang, B., Winter, M. C., He, N., Liu, X., Luo, M., Yang, Y., Ode, K. L., Uc, A., Norris, A. W. & Engelhardt, J. F. (2017). CFTR Influences Beta Cell Function and Insulin Secretion Through Non-Cell Autonomous Exocrine-Derived Factors. Endocrinology, 158(10), 3325-3338. PMID: 28977592.

Giefer, M. J., Lowe, M. E., Werlin, S. L., Zimmerman, B., Wilschanski, M., Troendle, D., Schwarzenberg, S. J., Pohl, J. F., Palermo, J., Ooi, C. Y., Morinville, V. D., Lin, T. K., Husain, S. Z., Himes, R., Heyman, M. B., Gonska, T., Gariepy, C. E., Freedman, S. D., Fishman, D. S., Bellin, M. D., Barth, B., Abu-El-Haija, M. & Uc, A. (2017). Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations. The Journal of pediatrics, 186, 95-100. PMID: 28502372.

Troendle, D. M., Fishman, D. S., Barth, B. A., Giefer, M. J., Lin, T. K., Liu, Q. Y., Abu-El-Haija, M., Bellin, M. D., Durie, P. R., Freedman, S. D., Gariepy, C., Gonska, T., Heyman, M. B., Himes, R., Husain, S. Z., Kumar, S., Lowe, M. E., Morinville, V. D., Ooi, C. Y., Palermo, J., Pohl, J. F., Schwarzenberg, S. J., Werlin, S., Wilschanski, M., Zimmerman, M. B. & Uc, A. (2017). Therapeutic Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients With Acute Recurrent and Chronic Pancreatitis: Data From the INSPPIRE (INternational Study group of Pediatric Pancreatitis: In search for a cuRE) Study. Pancreas, 46(6), 764-769. PMID: 28609364.

Uc, A., Fishman, D. S. (2017). Pancreatic Disorders. Pediatric clinics of North America, 64(3), 685-706. PMID: 28502446.

Gariepy, C. E., Heyman, M. B., Lowe, M. E., Pohl, J. F., Werlin, S. L., Wilschanski, M., Barth, B., Fishman, D. S., Freedman, S. D., Giefer, M. J., Gonska, T., Himes, R., Husain, S. Z., Morinville, V. D., Ooi, C. Y., Schwarzenberg, S. J., Troendle, D. M., Yen, E. & Uc, A. (2017). Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group. Journal of pediatric gastroenterology and nutrition, 64(1), 95-103. PMID: 27782962.

Uc, A., Andersen, D. K., Bellin, M. D., Bruce, J. I., Drewes, A. M., Engelhardt, J. F., Forsmark, C. E., Lerch, M. M., Lowe, M. E., Neuschwander-Tetri, B. A., O'Keefe, S. J., Palermo, T. M., Pasricha, P., Saluja, A. K., Singh, V. K., Szigethy, E. M., Whitcomb, D. C., Yadav, D. & Conwell, D. L. (2016). Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. (Vols. 45). (10), pp. 1365-1375. Pancreas. PMID: 27748719.

Yi, Y., Norris, A. W., Wang, K., Sun, X., Uc, A., Moran, A., Engelhardt, J. F. & Larson Ode, K. (2016). Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis. American journal of respiratory and critical care medicine. PMID: 27447840.

Kumar, S., Ooi, C. Y., Werlin, S., Abu-El-Haija, M., Barth, B., Bellin, M. D., Durie, P. R., Fishman, D. S., Freedman, S. D., Gariepy, C., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Husain, S. Z., Lin, T. K., Lowe, M. E., Morinville, V., Palermo, J. J., Pohl, J. F., Schwarzenberg, S. J., Troendle, D., Wilschanski, M., Zimmerman, M. B. & Uc, A. (2016). Risk Factors Associated With Pediatric Acute Recurrent and Chronic Pancreatitis: Lessons From INSPPIRE. JAMA pediatrics, 170(6), 562–569. PMID: 27064572.

Pohl, J., Morinville, V., Husain, S. Z. & Uc, A. (2016). Toxic-Metabolic Risk Factors Are Uncommon in Pediatric Chronic Pancreatitis. Journal of pediatric gastroenterology and nutrition, 62(6), e66-7. PMID: 27213250.

Husain, S. Z., Morinville, V., Pohl, J., Abu-El-Haija, M., Bellin, M. D., Freedman, S., Hegyi, P., Heyman, M. B., Himes, R., Ooi, C. Y., Schwarzenberg, S. J., Usatin, D. & Uc, A. (2016). Toxic-metabolic Risk Factors in Pediatric Pancreatitis: Recommendations for Diagnosis, Management, and Future Research. Journal of pediatric gastroenterology and nutrition, 62(4), 609-17. PMID: 26594832.

Ting, J., Wilson, L., Schwarzenberg, S. J., Himes, R., Barth, B., Bellin, M. D., Durie, P. R., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Husain, S. Z., Kumar, S., Morinville, V. D., Lowe, M. E., Ooi, C. Y., Pohl, J. F., Troendle, D., Usatin, D., Werlin, S. L., Wilschanski, M., Heyman, M. B. & Uc, A. (2016). Direct Costs of Acute Recurrent and Chronic Pancreatitis in Children in the INSPPIRE Registry. Journal of pediatric gastroenterology and nutrition, 62(3), 443-9. PMID: 26704866.

Yi, Y., Sun, X., Gibson-Corley, K., Xie, W., Liang, B., He, N., Tyler, S. R., Uc, A., Philipson, L. H., Wang, K., Hara, M., Larson Ode, K., Norris, A. W. & Engelhardt, J. F. (2016). A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology, en20151935. PMID: 26862997.

Hegyi, P., Wilschanski, M., Muallem, S., Lukacs, G. L., Sahin-Tóth, M., Uc, A., Gray, M. A., Rakonczay, Jr, Z. & Maléth, J. (2016). CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis. Reviews of physiology, biochemistry and pharmacology. PMID: 26856995.

(2016). “Recurrent Acute and Chronic Pancreatitis in Children Has High Disease Burden, Health Care Costs”. In http://wolterskluwer.com/company/newsroom/news/2016/01/recurrent-acute-and-chronic-pancreatitis-in-children-has-high-disease-burden-health-care-costs.html. Wolters Kluwer Press Release..

Ting, J., Wilson, L., Schwarzenberg, S. J., Himes, R., Barth, B., Bellin, M. D., Durie, P. R., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Husain, S. Z., Kumar, S., Morinville, V. D., Lowe, M. E., Ooi, C. Y., Pohl, J. F., Troendle, D., Usatin, D., Werlin, S. L., Wilschanski, M., Heyman, M. B. & Uc, A. (2016). Direct costs of acute recurrent and chronic pancreatitis in children in the INSPPIRE registry. Journal of Pediatric Gastroenterology and Nutrition, 62(3), 443-449.

Wilschanski, M., Uc, A. (2015). Cystic fibrosis. In S. Guandalini , A. Dhawan , D. Branski (Eds.) Textbook of Pediatric Gastroenterology, Hepatology and Nutrition. pp. 471-485. Springer. DOI: 10.1007/978-3-319-17169-2_41.

Uc, A., Wilschanski, M. (2015). Hereditary pancreatitis and chronic pancreatitis. In S. Guandalini , A. Dhawan , D. Branski (Eds.) Textbook of Pediatric Gastroenterology, Hepatology and Nutrition. pp. 395-403. Springer. DOI: 10.1007/978-3-319-17169-2_34.

Pohl, J. F., Uc, A. (2015). Paediatric pancreatitis. Current opinion in gastroenterology, 31(5), 380-6. PMID: 26181572.

Uc, A. (2015). Death in Pediatric Intensive Care Unit: Not for Children With Acute Pancreatitis. (Vols. 61). (1), pp. 1-2. Journal of pediatric gastroenterology and nutrition. PMID: 25988563.

Schwarzenberg, S. J., Bellin, M., Husain, S. Z., Ahuja, M., Barth, B., Davis, H., Durie, P. R., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Kumar, S., Morinville, V. D., Lowe, M. E., Nuehring, N. E., Ooi, C. Y., Pohl, J. F., Troendle, D., Werlin, S. L., Wilschanski, M., Yen, E. & Uc, A. (2015). Pediatric chronic pancreatitis is associated with genetic risk factors and substantial disease burden. The Journal of pediatrics, 166(4), 890-6.e1. PMID: 25556020.

Com, G., Uc, A. (2015). Exercise intolerance, malnutrition, abnormal sweat chloride levels, and two CFTR mutations: is it cystic fibrosis?. Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners, 29(2), 201-4. PMID: 25060775.

Com, G., Uc, A. (2015). Exercise intolerance, malnutrition, abnormal sweat chloride levels, and two CFTR mutations: is it cystic fibrosis?. Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners, 29(2), 201-4. PMID: 25060775.

Yi, Y., Sun, X., Gibson-Corley, K., Xie, W., Liang, B., He, N., Tyler, S. R., Uc, A., Philipson, L., Wang, K., Hara, M., Larson Ode, K., Norris, A. & Engelhardt, J. (2015). A transient metablic recovery from early life glucose intolerance in cystic fibrosis ferrets. Pediatric Pulmonology, 50, 418.

Uc, A. (2015). Death in Pediatric Intensive Care Unit: Not for Children with Acute Pancreatitis. Journal of Pediatric Gastroenterology and Nutrition, 61(1), 1-2.

Uc, A., Olivier, A. K., Griffin, M. A., Meyerholz, D. K., Yao, J., Abu-El-Haija, M., Buchanan, K. M., Vanegas Calderón, O. G., Abu-El-Haija, M., Pezzulo, A. A., Reznikov, L. R., Hoegger, M. J., Rector, M. V., Ostedgaard, L. S., Taft, P. J., Gansemer, N. D., Ludwig, P. S., Hornick, E. E., Stoltz, D. A., Ode, K. L., Welsh, M. J., Engelhardt, J. F. & Norris, A. W. (2015). Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979), 128(2), 131-142.

Uc, A., Olivier, A. K., Griffin, M. A., Meyerholz, D. K., Yao, J., Abu-El-Haija, M., Buchanan, K. M., Vanegas Calderón, O. G., Abu-El-Haija, M., Pezzulo, A. A., Reznikov, L. R., Hoegger, M. J., Rector, M. V., Ostedgaard, L. S., Taft, P. J., Gansemer, N. D., Ludwig, P. S., Hornick, E. E., Stoltz, D. A., Ode, K. L., Welsh, M. J., Engelhardt, J. F. & Norris, A. W. (2015). Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979), 128(2), 131-42. PMID: 25142104.

Azhari, H., Rahhal, R. & Uc, A. (2015). Is Total Pancreatectomy with Islet Autotransplantation A Reasonable Choice for Pediatric Pancreatitis?. JOP : Journal of the pancreas, 16(4), 335-41. PMID: 26523129.

Pohl, J. F., Uc, A. (2015). Paediatric pancreatitis. Current Opinion in Gastroenterology, 31(5), 380-386.

Schwarzenberg, S. J., Bellin, M., Husain, S. Z., Ahuja, M., Barth, B., Davis, H., Durie, P. R., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Kumar, S., Morinville, V. D., Lowe, M. E., Nuehring, N. E., Ooi, C. Y., Pohl, J. F., Troendle, D., Werlin, S. L., Wilschanski, M., Yen, E. & Uc, A. (2015). Pediatric chronic pancreatitis is associated with genetic risk factors and substantial disease burden. Journal of Pediatrics, 166(4), 890-896.

Husain, S. Z., Morinville, V., Pohl, J., Abu-El-Haija, M., Bellin, M. D., Freedman, S., Hegyi, P., Heyman, M. B., Himes, R., Ooi, C. Y., Schwarzenberg, S. J., Usatin, D. & Uc, A. (2015). Toxic-Metabolic Risk Factors in Pediatric Pancreatitis: Recommendations for Diagnosis, Management and Future Research. Journal of Pediatric Gastroenterology and Nutrition.

Uc, A., Giefer, M., Lowe, M. E. & Werlin, S. (2015). Very early onset acute recurrent and chronic pancreatitis are associated with PRSS1 or CTRC mutations. Pancreas, 44(8), 1421.

Morinville, V. D., Lowe, M. E., Ahuja, M., Barth, B., Bellin, M. D., Davis, H., Durie, P. R., Finley, B., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Husain, S., Kumar, S., Ooi, C. Y., Pohl, J. F., Schwarzenberg, S. J., Troendle, D., Werlin, S. L., Wilschanski, M., Yen, E. & Uc, A. (2014). Design and implementation of INSPPIRE. Journal of pediatric gastroenterology and nutrition, 59(3), 360-4. PMID: 24824361.

(2014). “INSPPIRED to find a cure for pediatric pancreatitis”. Institute for Clinical and translational Science (ICTS) Newsletter.

(2014). “INSPPIRED to find a cure”. Vice President of Medical Affairs (VPMA news)..

(2014). The UI Health Care People. Events. News. “INSPPIRE to find a cure for pediatric pancreatitis”. The Loop..

Griffin, M. A., Restrepo, M. S., Abu-El-Haija, M., Wallen, T., Buchanan, E., Rokhlina, T., Chen, Y. H., McCray, Jr, P. B., Davidson, B. L., Divekar, A. & Uc, A. (2014). A novel gene delivery method transduces porcine pancreatic duct epithelial cells. Gene therapy, 21(2), 123-30. PMID: 24257348.

Griffin, M. A., Restrepo, M. S., Abu-El-Haija, M., Wallen, T., Buchanan, E., Rokhlina, T., Chen, Y. H., McCray, Jr, P. B., Davidson, B. L., Divekar, A. & Uc, A. (2014). A novel gene delivery method transduces porcine pancreatic duct epithelial cells. Gene Therapy, 21(2), 123-130.

Morinville, V. D., Lowe, M. E., Ahuja, M., Barth, B., Bellin, M. D., Davis, H., Durie, P. R., Finley, B., Fishman, D. S., Freedman, S. D., Gariepy, C. E., Giefer, M. J., Gonska, T., Heyman, M. B., Himes, R., Husain, S., Kumar, S., Ooi, C. Y., Pohl, J. F., Schwarzenberg, S. J., Troendle, D., Werlin, S. L., Wilschanski, M., Yen, E. & Uc, A. (2014). Design and implementation of INSPPIRE. Journal of Pediatric Gastroenterology and Nutrition, 59(3), 360-364.

Wilson, L., Ting, J., Heyman, M. B., Yen, E. H., Usatin, D., Ahuja, M., Davis, H. & Uc, A. (2014). Economic burden of pediatric pancreatitis: Hospital costs. Gastroenterology, 146(5), S-803.

Griffin, M., Abu-El-Haija, M., Baltrusaitis, J., Thompson, J., Meyerholz, D. K., Peate, D. & Uc, A. (2014). Pancreatic calcium content is increased and concentrated in ductal structures of CF pigs: A possible mechanism of pancreatic damage in CF. Pediatric Pulmonology, 49, 419-420.

Uc, A. (2014). Pancreatic insufficiency. In , J. F. Pohl , C. Jolley , D. Gelfond (Eds.) Pediatric gastroenterology: a color handbook. Boca Raton: CRC Press.

Uc, A., Yen, E. H., Wilschanski, M., Werlin, S., Troendle, D., Schwarzenberg, S. J., Pohl, J., Ooi, C. Y., Morinville, V. D., Kumar, S., Husain, S. Z., Himes, R., Heyman, M. B., Gonska, T., Giefer, M. J., Gariepy, C. E., Freedman, S. D., Fishman, D. S., Durie, P. R., Davis, H., Bellin, M., Barth, B. A., Ahuja, M. & Lowe, M. (2014). Pediatric acute recurrent and chronic pancreatitis: Report from insppire consortium. Gastroenterology, 146(5), S-4.

Norris, A. W., Ryckman, K. K. & Uc, A. (2014). Perturbed mitochondrial oxidation of linoleic acid in newborns with cystic fibrosis. Pediatric Pulmonology, 49, 408-409.

Sui, H., Yi, Y., Yao, J., Liang, B., Sun, X., Hu, S., Uc, A., Nelson, D. J., Ode, K. L., Philipson, L. H., Engelhardt, J. F. & Norris, A. W. (2014). Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets. PloS one, 9(3), e90519. PMID: 24594704.

Bellin, M. D., Freeman, M. L., Gelrud, A., Slivka, A., Clavel, A., Humar, A., Schwarzenberg, S. J., Lowe, M. E., Rickels, M. R., Whitcomb, D. C., Matthews, J. B., Amann, S., Andersen, D. K., Anderson, M. A., Baillie, J., Block, G., Brand, R., Chari, S., Cook, M., Cote, G. A., Dunn, T., Frulloni, L., Greer, J. B., Hollingsworth, M. A., Kim, K. M., Larson, A., Lerch, M. M., Lin, T., Muniraj, T., Robertson, R. P., Sclair, S., Singh, S., Stopczynski, R., Toledo, F. G., Wilcox, C. M., Windsor, J. & Yadav, D. (2014). Total pancreatectomy and islet autotransplantation in chronic pancreatitis: recommendations from PancreasFest. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 14(1), 27-35. PMID: 24555976.

Troendle, D., Barth, B. A., Giefer, M. J., Uc, A., Ahuja, M., Davis, H. & Fishman, D. S. (2014). Use of ERCP in pediatric patients with acute recurrent and chronic pancreatitis: A report from the insppire (international study group of pediatric pancreatitis: In search for a cure) consortium. Gastrointestinal Endoscopy, 79(5), AB285-AB286.

Rahhal, R., Uc, A. (2014). Motility disorders [and] functional constipation. In R. E. Kleinman (Eds.) Walker's pediatric gastrointestinal disease. (5th edition), pp. 675-682. Shelton: PMPH USA.

Rickels, M. R., Bellin, M., Toledo, F. G., Robertson, R. P., Andersen, D. K., Chari, S. T., Brand, R., Frulloni, L., Anderson, M. A. & Whitcomb, D. C. (2013). Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest 2012. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 13(4), 336-42. PMID: 23890130.

Uc, A. (2013). Predicting the severity of pediatric acute pancreatitis: are we there yet?. Journal of pediatric gastroenterology and nutrition, 56(6), 584-5. PMID: 23535763.

Uc, A., Griffin, M. A., Abu-El-Haija, M., Restrepo, M. S., Wallen, T., McCray, Jr, P. B., Davidson, B. L. & Divekar, A. (2013). A novel delivery method to transduce genes in the pancreas. Pancreatology, 13(2), e80.

Griffin, M. A., Restrepo, M. S., Abu-El-Haija, M., Wallen, T., Buchanan, E., Rokhlina, T., Chen, Y. H., McCray, Jr, P. B., Davidson, B. L., Divekar, A. & Uc, A. (2013). A novel gene delivery method transduces porcine pancreatic duct epithelial cells. Gene Therapy.

Griffin, M., Restrepo, M., Abu-El-Haija, M., Wallen, T., Buchanan, E., Rokhlina, T., Chen, Y., McCray, Jr, P., Davidson, B., Divekar, A. & Uc, A. (2013). A novel gene delivery method transduces porcine pancreatic duct epithelial cells that express CFTR. Pediatric Pulmonology, 48, 404.

Uc, A., Schwarzenberg, S., Bellin, M., Fishman, D., Himes, R., Gonska, T., Troendle, D., Barth, B., Heyman, M., Hussain, S., Giefer, M., Werlin, S., Gariepy, C., Wilschanski, M., Morinville, V., Ooi, C. Y., Pohl, J., Freedman, S., Durie, P. R., Lowe, M. & Ahuja, M. (2013). CFTR mutations are commonly found in children with acute recurrent and chronic pancreatitis. Pediatric Pulmonology, 48, 416.

Uc, A., Coleman, M., McCormick, M., Griffin, M., Meyerholz, D. K., Olivier, A. K., Yi, Y., Sun, X., Welsh, M. J., Engelhardt, J., Norris, A. W. & Spitz, D. R. (2013). Impaired islet cell function in newborn cystic fibrosis pigs and ferrets may be related to pancreatic oxidative stress. Pediatric Pulmonology, 48, 419.

Uc, A. (2013). Predicting the severity of pediatric acute pancreatitis: Are we there yet?. Journal of Pediatric Gastroenterology and Nutrition, 56(6), 584-585.

Uc, A. (2013). “Pancreatic Disorders”.

(2012). “Pancreatitis Registry Created”. Vice President of Medical Affairs (VPMA news).

Uc, A. (2012). Interview with Iowa Now. “UI creates first patient registry for childhood pancreatic disease”.

Uc, A., Giriyappa, R., Meyerholz, D. K., Griffin, M., Ostedgaard, L. S., Tang, X. X., Abu-El-Haija, M., Stoltz, D. A., Ludwig, P., Pezzulo, A., Abu-El-Haija, M., Taft, P. & Welsh, M. J. (2012). Pancreatic and biliary secretion are both altered in cystic fibrosis pigs. American journal of physiology. Gastrointestinal and liver physiology, 303(8), G961-8. PMID: 22936270.

Abu-El-Haija, M., Ramachandran, S., Meyerholz, D. K., Abu-El-Haija, M., Griffin, M., Giriyappa, R. L., Stoltz, D. A., Welsh, M. J., McCray, Jr, P. B. & Uc, A. (2012). Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways. The American journal of pathology, 181(2), 499-507. PMID: 22683312.

Griffin, M., Abu-El-Haija, M., Abu-El-Haija, M., Rokhlina, T. & Uc, A. (2012). Simplified and versatile method for isolation of high-quality RNA from pancreas. BioTechniques, 52(5), 332-4. PMID: 22578126.

Uc, A., Zhu, X., Wagner, B. A., Buettner, G. R. & Berg, D. J. (2012). Heme oxygenase-1 is protective against nonsteroidal anti-inflammatory drug-induced gastric ulcers. Journal of pediatric gastroenterology and nutrition, 54(4), 471-6. PMID: 21873894.

Uc, A., Griffin, M. A., Abu-El-Haija, M., Restrepo, M. S., Wallen, T., McCray, Jr, P. B., Davidson, B. L. & Divekar, A. (2012). A novel delivery method to transduce genes in the pancreas. Pancreas, 41(8), 1409-1410.

Olivier, A. K., Meyerholz, D. K., Abu-El-Haija, M., Griffin, M., Abu-El-Haija, M., Stoltz, D. A., Ludwig, P., Ode, K. L., Welsh, M. J., Norris, A. W. & Uc, A. (2012). Abnormal glycemic regulation in cystic fibrosis pigs is not associated with deficient immunohistochemical expression of insulin or glucagon in the pancreas. Pediatric Pulmonology, 47, 285.

Morinville, V. D., Husain, S. Z., Bai, H., Barth, B., Alhosh, R., Durie, P. R., Freedman, S. D., Himes, R., Lowe, M. E., Pohl, J., Werlin, S., Wilschanski, M. & Uc, A. (2012). Definitions of pediatric pancreatitis and survey of present clinical practices. Journal of Pediatric Gastroenterology and Nutrition, 55(3), 261-265. DOI: 10.1097/MPG.0b013e31824f1516.

Griffin, M., Abu-El-Haija, M., Restrepo, M., Wallen, T., McCray, P. B., Davidson, B. L., Divekar, A. & Uc, A. (2012). Delivery of adeno-associated-9 vector to newborn pigs transduces genes in the pancreas. Pediatric Pulmonology, 47, 418.

Uc, A. (2012). Development of pancreatic insufficiency in CF: Lessons from humans & pigs. Pediatric Pulmonology, 47, 131-133.

Uc, A., Zhu, X., Wagner, B. A., Buettner, G. R. & Berg, D. J. (2012). Heme oxygenase-1 is protective against nonsteroidal anti-inflammatory drug-induced gastric ulcers. Journal of Pediatric Gastroenterology and Nutrition, 54(4), 471-476.

Stoltz, D., Meyerholz, D. K., Rokhlina, T., Pezzulo, A. A., Ostedgaard, L. S., Ernst, S. E., Ludwig, P. S., Reznikov, L. R., Uc, A., McCray, P. B., Zabner, J., Karp, P. H., Welsh, M. J., Samuel, M. & Prather, R. (2012). Intestinal expression of CFTR alleviates the meconium ileus phenotype in cystic fibrosis pigs. Journal of Investigative Medicine, 60(4), 743.

Uc, A., Liu, X., Griffin, M. A., Welti, R., Hornick, E., Welsh, M., Engelhardt, J., Norris, A. W. & Strandvik, B. (2012). Newborn cystic fibrosis pigs and ferrets have fatty acid alterations similar to humans. Pediatric Pulmonology, 47, 407-408.

Uc, A., Giriyappa, R., Meyerholz, D. K., Griffin, M., Ostedgaard, L. S., Tang, X. X., Abu-El-Haija, M., Stoltz, D. A., Ludwig, P., Pezzulo, A., Abu-El-Haija, M., Taft, P. & Welsh, M. J. (2012). Pancreatic and biliary secretion are both altered in cystic fibrosis pigs. American Journal of Physiology - Gastrointestinal and Liver Physiology, 303(8), G961-G968.

Abu-El-Haija, M., Ramachandran, S., Meyerholz, D. K., Abu-El-Haija, M., Griffin, M., Giriyappa, R. L., Stoltz, D. A., Welsh, M. J., McCray, Jr, P. B. & Uc, A. (2012). Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways. American Journal of Pathology, 181(2), 499-507.

Griffin, M., Abu-El-Haija, M., Abu-El-Haija, M., Rokhlina, T. & Uc, A. (2012). Simplified and versatile method for isolation of high-quality RNA from pancreas. BioTechniques, 52(5), 332-334.

Ostedgaard, L. S., Meyerholz, D. K., Chen, J. H., Pezzulo, A. A., Karp, P. H., Rokhlina, T., Ernst, S. E., Hanfland, R. A., Reznikov, L. R., Ludwig, P. S., Rogan, M. P., Davis, G. J., Dohrn, C. L., Wohlford-Lenane, C., Taft, P. J., Rector, M. V., Hornick, E., Nassar, B. S., Samuel, M., Zhang, Y., Richter, S. S., Uc, A., Shilyansky, J., Prather, R. S., McCray, Jr, P. B., Zabner, J., Welsh, M. J. & Stoltz, D. A. (2011). The ?F508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Science translational medicine, 3(74), 74ra24. PMID: 21411740.

Abu-El-Haija, M., Sinkora, M., Meyerholz, D. K., Welsh, M. J., McCray, Jr, P. B., Butler, J. & Uc, A. (2011). An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis. Pancreatology, 11(5), 506-515.

Abu-El-Haija, M., Sinkora, M., Meyerholz, D. K., Welsh, M. J., McCray, Jr, P. B., Butler, J. & Uc, A. (2011). An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 11(5), 506-15. PMID: 22057257.

Meyerholz, D. K., Olivier, A. K., Hochstedler, C., Naumann, P., Stoltz, D. A., McCray, P. B., Welsh, M. J. & Uc, A. (2011). Beta cell distribution, But not beta cell density, is altered in the neonatal CF pig pancreas. Pediatric Pulmonology, 46, 403.

Uc, A. (2011). Chronic pancreatitis in children: current knowledge in diagnosis and treatment. Journal of Pediatric Sciences, 3(4).

Al-Zubeidi, D., Uc, A. (2011). Intestinal duplication cysts. In , J. M. Soundheimer , C. W. Hurtado (Eds.) The NASPGHAN Fellows concise review of pediatric gastroenterology, hepatology and nutrition. pp. 79–80. New York, NY: CCGMP.

Stoltz, D. A., Meyerholz, D. K., Pezzulo, A. A., Rokhlina, T., Chen, J., Ostedgaard, L. S., Karp, P. H., Ernst, S. E., Ludwig, P. S., Rector, M. V., Reznikov, L., Taft, P. J., Wohlford-Lenane, C., Dohrn, C., Hornick, E. E., Gansemer, N. D., Hoegger, M., Samuel, M. S., Brogden, K. A., Uc, A., McCray, P. B., Zabner, J., Prather, R. S. & Welsh, M. J. (2011). Intestinal expression of CFTR alleviates the meconium ileus phenotype in cystic fibrosis pigs. Pediatric Pulmonology, 46, 276.

Al-Zubeidi, D., Uc, A. (2011). Meckel diverticulum. In , J. M. Soundheimer , C. W. Hurtado (Eds.) The NASPGHAN Fellows concise review of pediatric gastroenterology, hepatology and nutrition. pp. 75–76. New York, NY: CCGMP.

Meyerholz, D. K., Stoltz, D. A., Uc, A., McCray, P. B. & Welsh, M. J. (2011). Morphometric analysis of exocrine pig pancreas suggests a sequential pathogenesis for fetal CF pancreas disease. Pediatric Pulmonology, 46, 279.

Uc, A., Stoltz, D. A., Ludwig, P. S., Pezzulo, A., Griffin, M., Abu-El-Haija, M., Abu-El-Haija, M., Meyerholz, D., Taft, P. J. & Welsh, M. J. (2011). Pancreatic and biliary secretion differ in cystic fibrosis and wild-type pigs. Gastroenterology, 140(5), S856.

Uc, A., Stoltz, D. A., Ludwig, P., Pezzulo, A., Griffin, M., Abu-El-Haija, M., Abu-El-Haija, M., Meyerholz, D. K., Taf, P. & Welsh, M. J. (2011). Pancreatic and biliary secretion differ in cystic fibrosis and wild-type pigs. Journal of Cystic Fibrosis, 10, S69.

Abu-El-Haija, M., Ramachandran, S., Meyerholz, D. K., Abu-El-Haija, M., Griffin, M., Giriyappa, R., Welsh, M. J., McCray, P. & Uc, A. (2011). Pancreatic damage in a cystic fibrosis pig model involves the activation of proinflammatory pathways. Pediatric Pulmonology, 46, 394-395.

Husain, S. Z., Bai, H. X., Barth, B. A., Wilschanski, M., Alhosh, R., Durie, P. R., Lowe, M., Morinville, V. D. & Uc, A. (2011). Practice patterns of pediatric gastroenterologists caring for children with acute and chronic pancreatitis. Gastroenterology, 140(5), S685.

Ostedgaard, L. S., Meyerholz, D. K., Chen, J. H., Pezzulo, A. A., Karp, P. H., Rokhlina, T., Ernst, S. E., Hanfland, R. A., Reznikov, L. R., Ludwig, P. S., Rogan, M. P., Davis, G. J., Dohrn, C. L., Wohlford-Lenane, C., Taft, P. J., Rector, M. V., Hornick, E., Nassar, B. S., Samuel, M., Zhang, Y., Richter, S. S., Uc, A., Shilyansky, J., Prather, R. S., McCray, Jr, P. B., Zabner, J., Welsh, M. J. & Stoltz, D. A. (2011). The ?F508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Science Translational Medicine, 3(74).

Stoltz, D. A., Meyerholz, D. K., Pezzulo, A. A., Ramachandran, S., Rogan, M. P., Davis, G. J., Hanfland, R. A., Wohlford-Lenane, C., Dohrn, C. L., Bartlett, J. A., Nelson, 4th, G. A., Chang, E. H., Taft, P. J., Ludwig, P. S., Estin, M., Hornick, E. E., Launspach, J. L., Samuel, M., Rokhlina, T., Karp, P. H., Ostedgaard, L. S., Uc, A., Starner, T. D., Horswill, A. R., Brogden, K. A., Prather, R. S., Richter, S. S., Shilyansky, J., McCray, Jr, P. B., Zabner, J. & Welsh, M. J. (2010). Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science translational medicine, 2(29), 29ra31. PMID: 20427821.

Uc, A., McDonagh, A. F. & Stokes, J. B. (2010). Metabolism of haem in Caco-2 cells. Experimental physiology, 95(2), 296-303. PMID: 19880533.

Stoltz, D. A., Meyerholz, D. K., Pezzulo, A. A., Ramachandran, S., Rogan, M. P., Davis, G. J., Hanfland, R. A., Wohlford-Lenane, C., Dohrn, C. L., Bartlett, J. A., Nelson, Iv, G. A., Eugene, C., Taft, P. J., Ludwig, P. S., Estin, M., Hornick, E. E., Launspach, J. L., Samuel, M., Rokhlina, T., Karp, P. H., Ostedgaard, L. S., Uc, A., Starner, T. D., Horswill, A. R., Brogden, K. A., Prather, R. S., Richter, S. S., Shilyansky, J., McCray, Jr, P. B., Zabner, J. & Welsh, M. J. (2010). Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science Translational Medicine, 2(29), 29ra31.

Meyerholz, D. K., Stoltz, D. A., Pezzulo, A. A., Welsh, M. J. & Uc, A. (2010). Early progression of CF pancreatic disease in fetal CFTR-/- pigs. Pediatric Pulmonology, 45, 426-427.

Abu-El-Haija, M., Sinkora, M., Ramachandran, S., Ludwig, P., Butler, J., McCray, P. & Uc, A. (2010). Immune response is activated in the cystic fibrosis pig pancreas at birth. Pediatric Pulmonology, 45, 426.

Abu El Haija, M.,, Sinkora, M., Ramachandran, S., Ludwig, P., Meyerholz, D., Butler, J., Welsh, M., McCray, P. & Uc, A. (2010). Inflammation contributes to the pathogenesis of pancreatic lesions in cystic fibrosis. Journal of Pediatric Gastroenterology and Nutrition, 51, E106-E107.

Uc, A., McDonagh, A. F. & Stokes, J. B. (2010). Metabolism of haem in Caco-2 cells: Experimental Physiology-Research Paper. Experimental Physiology, 95(2), 296-303.

Uc, A. (2010). Pancreatic insufficiency/cystic fibrosis. In , W. P. Bishop (Eds.) Pediatric practice.. New York: McGraw-Hill Medical.

Uc, A., Pandrangi, B. P. (2010). Peptic ulcer disease. In W. P. Bishop (Eds.) Pediatric practice. Gastroenterology. New York: McGraw-Hill Medical.

Uc, A., Zhu, X. & Whitehead, R. H. (2009). Characterization of a novel gastric epithelial cell line. Journal of Pediatric Gastroenterology and Nutrition, 49, E83-E84.

Pashankar, D., Uc, A., Saeed, S., Smith, L. J., Huang, J. S., Treem, W. R. & Gilger, M. A. (2009). Common clinical problems facing pediatric gastroenterologists in outpatient clinics at academic centers. Gastroenterology, 136(5), A504.

Phatak, U., Uc, A., Saeed, S., Smith, L., Huang, J., Treem, W., De Felice, A., Erdman, S., Rufo, P., Gilger, M. & Pashankar, D. (2009). Common inpatient clinical problems facing pediatric gastroenterologists at academic centers. Journal of Pediatric Gastroenterology and Nutrition, 49, E59.

Uc, A., Meyerholz, D., Giriyappa, R., Ramachandran, S., Ostedgaard, L., Stoltz, D., Welsh, M. & McCray, P. (2009). Pancreatic involvement in a porcine cystic fibrosis model. Journal of Pediatric Gastroenterology and Nutrition, 49, E103.

Rogers, C. S., Stoltz, D. A., Meyerholz, D. K., Ostedgaard, L. S., Rokhlina, T., Taft, P. J., Rogan, M. P., Pezzulo, A. A., Karp, P. H., Itani, O. A., Kabel, A. C., Wohlford-Lenane, C. L., Davis, G. J., Hanfland, R. A., Smith, T. L., Samuel, M., Wax, D., Murphy, C. N., Rieke, A., Whitworth, K., Uc, A., Starner, T. D., Brogden, K. A., Shilyansky, J., McCray, Jr, P. B., Zabner, J., Prather, R. S. & Welsh, M. J. (2008). Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (New York, N.Y.), 321(5897), 1837-41. PMID: 18818360.

Rogers, C. S., Stoltz, D. A., Meyerholz, D. K., Ostedgaard, L. S., Rokhlina, T., Taft, P. J., Rogan, M. P., Pezzulo, A. A., Karp, P. H., Itani, O. A., Kabel, A. C., Wohlford-Lenane, C. L., Davis, G. J., Hanfland, R. A., Smith, T. L., Samuel, M., Wax, D., Murphy, C. N., Rieke, A., Whitworth, K., Uc, A., Starner, T. D., Brogden, K. A., Shilyansky, J., McCray, Jr, P. B., Zabner, J., Prather, R. S. & Welsh, M. J. (2008). Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science, 321(5897), 1837-1841.

Rahhal, R., Uc, A. (2008). Idiopathic constipation. In , R. E. Kleinman , W. A. Walker (Eds.) Walker’s pediatric gastrointestinal disease: physiology, diagnosis, management. pp. 675–682. Hamilton, Ont.; Lewiston, NY: BC Decker.

Uc, A., Reszka, K. J., Buettner, G. R. & Stokes, J. B. (2007). Tin protoporphyrin induces intestinal chloride secretion by inducing light oxidation processes. American journal of physiology. Cell physiology, 292(5), C1906-14. PMID: 17215323.

Uc, A., Reszka, K. J., Buettner, G. R. & Stokes, J. B. (2007). Tin protoporphyrin induces intestinal chloride secretion by inducing light oxidation processes. American Journal of Physiology - Cell Physiology, 292(5), C1906-C1914.

Uc, A., Hyman, P. E. & Walker, L. S. (2006). Functional gastrointestinal disorders in African American children in primary care. Journal of pediatric gastroenterology and nutrition, 42(3), 270-4. PMID: 16540795.

Uc, A. (2005). Interview with the Scientist magazine: “How heme gets in?”.

Uc, A., Husted, R. F., Giriyappa, R. L., Britigan, B. E. & Stokes, J. B. (2005). Hemin induces active chloride secretion in Caco-2 cells. American journal of physiology. Gastrointestinal and liver physiology, 289(2), G202-8. PMID: 15805100.

Uc, A., Stokes, J. B. & Britigan, B. E. (2004). Heme transport exhibits polarity in Caco-2 cells: evidence for an active and membrane protein-mediated process. American journal of physiology. Gastrointestinal and liver physiology, 287(6), G1150-7. PMID: 15308469.

Uc, A., Roy, J. & Carver, L. A. (2004). Is recurrent abdominal pain of childhood a psychosomatic disorder?. Journal of pediatric gastroenterology and nutrition, 39(5), 571-2. PMID: 15572905.

Pashankar, D. S., Uc, A. & Bishop, W. P. (2004). Polyethylene glycol 3350 without electrolytes: a new safe, effective, and palatable bowel preparation for colonoscopy in children. The Journal of pediatrics, 144(3), 358-62. PMID: 15001943.

Uc, A., Kooy, N. W., Conklin, J. L. & Bishop, W. P. (2003). Peroxynitrite inhibits epidermal growth factor receptor signaling in Caco-2 cells. Digestive diseases and sciences, 48(12), 2353-9. PMID: 14714624.

Uc, A., Britigan, B. E. (2003). Does heme oxygenase-1 have a role in Caco-2 cell cycle progression?. Experimental biology and medicine (Maywood, N.J.), 228(5), 590-5. PMID: 12709592.

Uc, A. (2003). Is there another role for nitric oxide?. Journal of Pediatric Gastroenterology and Nutrition, 36(1), 156-157.

Uc, A., Chong, S. K. (2002). Treatment of Helicobacter pylori gastritis improves dyspeptic symptoms in children. Journal of Pediatric Gastroenterology and Nutrition, 34(3), 281-285.

Uc, A., Murray, J. A., Kooy, N. & Conklin, J. L. (2001). Effect of peroxynitrite on motor function of the opossum esophagus. Digestive diseases and sciences, 46(1), 30-7. PMID: 11270791.

Uc, A., Bishop, W. P. & Sanders, K. D. (2000). Camphor hepatotoxicity. Southern medical journal, 93(6), 596-8. PMID: 10881777.

Uc, A., North, P. & Burks, W. (2000). Esophageal candidiasis in an infant with reflux esophagitis. Journal of Pediatric Gastroenterology and Nutrition, 31(5), 572-574.

Uc, A., Oh, S. T., Murray, J. A., Clark, E. & Conklin, J. L. (1999). Biphasic relaxation of the opossum lower esophageal sphincter: roles of NO., VIP, and CGRP. The American journal of physiology, 277(3 Pt 1), G548-54. PMID: 10484379.

Uc, A., Oh, S. T., Murray, J. A., Clark, E. & Conklin, J. L. (1999). Biphasic relaxation of the opossum lower esophageal sphincter: Roles of NO·, VIP, and CGRP. American Journal of Physiology - Gastrointestinal and Liver Physiology, 277(3 40-3), G548-G554.

Uc, A., Hyman, P. (1999). Gastic motility disorders. In , R. Wyllie , J. S. Hyams (Eds.) Pediatric gastrointestinal disease: pathophysiology, diagnosis, management. pp. 257–264. Philadelphia: W.B. Saunders Co..

Uc, A., Kao, S. C., Sanders, K. D. & Lawrence, J. (1998). Gastric volvulus and wandering spleen. The American journal of gastroenterology, 93(7), 1146-8. PMID: 9672348.

Uc, A., Murray, J. A. & Conklin, J. L. (1997). Effects of calcitonin gene-related peptide on opossum esophageal smooth muscle. Gastroenterology, 113(2), 514-20. PMID: 9247471.

Uc, A., Hoon, A., Di Lorenzo, C. & Hyman, P. E. (1997). Antroduodenal manometry in children with no upper gastrointestinal symptoms. Scandinavian journal of gastroenterology, 32(7), 681-5. PMID: 9246708.

Uc, A., Vasiliauskas, E., Piccoli, D. A., Flores, A. F., Di Lorenzo, C. & Hyman, P. E. (1997). Chronic intestinal pseudoobstruction associated with fetal alcohol syndrome. Digestive diseases and sciences, 42(6), 1163-7. PMID: 9201078.

Uc, A., Mitros, F. A., Kao, S. C. & Sanders, K. D. (1997). Pseudomembranous colitis with Escherichia coli O157:H7. Journal of pediatric gastroenterology and nutrition, 24(5), 590-3. PMID: 9161956.

Tomomasa, T., DiLorenzo, C., Morikawa, A., Uc, A. & Hyman, P. E. (1996). Analysis of fasting antroduodenal manometry in children. Digestive Diseases and Sciences, 41(11), 2195-2203.

Yetgin, S., Uç, A., Ozbek, N. & Hiçsönmez, G. (1995). Reactive plasmacytosis and plasmacytic skin infiltration in a patient. (Vols. 55). (2), pp. 131-2. European journal of haematology. PMID: 7628588.

Yetgin, S., Uc, A., Ozbek, N. & Hicsonmez, G. (1995). Reactive plasmacytosis and plasmacytic skin infiltration in a patient [1]. European Journal of Haematology, 55(2), 131-132.

Yetgin, S., Sungurtekin, N. & Uc, A. (1993). A variant form of dyskeratosis congenita. Cocuk Sagligi ve Hastaliklari Dergisi, 36, 143-146.

Uc, A., Ozsoylu, S. (1992). Age-prevalence of Hb8Ag positivity in children seen at Hacettepe Children's Hospital. Turkish Journal of Medical Research, 10, 264-266.

Uc, A., Atalay, S., Ozme, S., Ozkutlu, S., Altay, C. & Gungen, Y. (1991). Myxoma syndrome: a case report. Cocuk Sagligi ve Hastaliklari Dergisi, 34, 223-228.