Liuska M. Pesce, MD

Portrait
Clinical Associate Professor
Clinical Associate Professor of Pediatrics - Endocrinology and Diabetes

Contact Information

Primary Office
2025 BT
200 Hawkins Drive
Iowa City, IA 52242
319-35-356-3164

Education

MD, Central University of Venezuela, Luis Razetti School of Medicine
Postdoctoral Fellow, Research Post-Doctoral Fellowship, Michael Reese Hospital, University of Illinois at Chicago
Postdoctoral Fellow, Research Post-Doctoral Fellowship, Northwestern Memorial Hospital, Northwestern University, Chicago, Illinois
Internship, Pediatrics, University of Illinois at Chicago, Chicago, Illinois
Resident, Pediatrics, University of Illinois at Chicago
Fellow, Pediatric Endocrinology, Children's Memorial Hospital, Northwestern University, Chicago, Illinois

Licensure and Certifications

Human Subjects Protection (CITI)
American Board of Pediatric Endocrinology
Iowa Controlled Substance License
Permanent Iowa Medical License

Publications

Pesce, L., Bizhanova, A., Caraballo, J. C., Westphal, W., Butti, M. L., Comellas, A. & Kopp, P. (2012). TSH Regulates Pendrin Membrane Abundance and enhances Iodide Efflux in Thyroid Cells. (Vols. 153). (1), pp. 512-21. Endocrinology. PMID: 22109890.

Comellas, A. P., Briva, A., Dada, L. A., Butti, M. L., Trejo, H., Yshii, C., Azzam, Z., Litvan, J., Chen, J., Lecuona, E., Pesce, L., Yanagisawa, M. & Sznajder, J. I. (2009). Endothelin-1 Impairs Alveolar Epithelial Function via Endothelial ET-B Receptor. (Vols. 179). (2), pp. 113-22. Am J Respir Crit Care Med. PMID: 18948426.

Kopp, P., Pesce, L. & Solis, J. C. (2008). Pendred Syndrome and iodide transport in the thyroid. (Vols. 19). (7), pp. 260-8. Trends Endocrinol and Metab. PMID: 18692402.

Comellas, A. P., Dada, L. A., Lecuona, E., Pesce, L., Chandel, N. S., Quesada, N., Budinger, G. R., Strous, G. J., Ciechanover, A. & Sznajder, J. K. (2006). Hypoxia-Mediated Degradation of Na,K-ATPase via Mitochondrial Reactive Oxygen Species and the Ubiquitin-Conjugating System. (Vols. 98). (10), pp. 1314-22. Circ Res. PMID: 16614303.

Adir, Y., Azzam, Z. S., Lecuona, E., Leal, S., Pesce, L., Dumasius, V., Bertorello, A. M., Factor, P., Young, J. B., Ridge, K. M. & Sznajder, J. I. (2004). Augmentation of endogenous dopamine production increases lung liquid clearanc. (Vols. 169). (6), pp. 757-63. Am J Respir Crit Care Med. PMID: 14701706.

Pesce, L., Comellas, A. & Sznajder, J. I. (2003). beta-adrenergic agonists regulate the Na,K-ATPase via the p70s6K. (Vols. 285). (4), pp. L802-7. Am J Physiol Lung Cell Mol Physiol. PMID: 12704019.

Lecuona, E., Ridge, K., Pesce, L., Batlle, D. & Sznajder, J. I. (2003). The GTP-binding protein RhoA mediates Na, K-ATPase exocytosis in alveolar epithelial cells. (Vols. 14). (9), pp. 3888-97. Mol Biol Cell. PMID: 12972572.

Comellas, A. P., Pesce, L., Azzam, Z., Saldias, F. J. & Sznajder, J. I. (2003). Scorpion venom decreases lung liquid clearance in rats. (Vols. 167). (8), pp. 1064-7. Am J Respir Crit Care Med. PMID: 12684245.

Saldias, F. J., Comellas, A., Pesce, L., Lecuona, E. & Sznajder, J. I. (2002). Dopamine increases lung liquid clearance during mechanical ventilation. (Vols. 283). (1), pp. L136-43. Am J Physiol Lung Cell Mol Physiol. PMID: 12060570.

Guerrero, C., Lecuona, E., Pesce, L., Ridge, K. M. & Sznajder, J. I. (2001). Dopamine regulates Na-K-ATPase in alveolar epithelial cells via MAPK-ERK-dependent mechanisms. (Vols. 281). (1), pp. L9-85. Am J Physiol Lung Cell Mol Physiol. PMID: 11404249.

Bizhanova, A., Pesce, L. & Kopp, P. (2017). The controversial Pendrin role in the thyroid and thyroid dysfunction in Pendred syndrome. In M. Paulmichl , S. Dossena (Eds.) The Role of Pendrin in health and disease. Springer.

Pesce, L. (In Press). Vignettes related to pediatric thyroid disorders. In Pediatric Endocrine Self Assessment Program 2017/2018. Endocrine Society.

Comellas, A. P., Pesce, L. M. (2014). Scorpion envenomation. The New England Journal of Medicine, 371(16), 1558. PMID: 25317886.

Pesce, L., Fang, M., Policeni, B., Axelson, R., Pettit, J. & Lenoch, S. (2014). Instructional technologies in medical education: an important need for faculty development. (Vols. 3). (29), pp. 1-13. AMEE MedEdPublish (www.mededworld.org).

Pesce, L., Kopp, P. (2014). Iodide Transport: Implications for Health and disease. International Journal of Pediatric Endocrinology, 8. DOI: DOI: 10.1186/1687-9856-2014-8.

(2013). Hypothyroidism: A Booklet for Patients and their Families. American Thyroid Association.

Kopp, P., Schnyder, S. & Pesce, L. (2009). Pendred syndrome: deficiency in iodide transport. In V. R. Preedy , G. N. Burrow & R. Watson (Eds.) Comprehensive Handbook of Iodine. Oxford: Academic Press.

Pesce, L., Zimmerman, D. (2008). Amenorrhea. In T. F. Davies (Eds.) A Case-Based Guide to Clinical Endocrinology. Humana Press.

Pesce, L., Zimmerman, D. (2008). Early puberty and hypothyroidism. In T. F. Davies (Eds.) A Case-Based Guide to Clinical Endocrinology. Humana Press.

Pesce, L., Comellas, A. & Sznajder, J. I. (2003). Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k. American Journal of Physiology. Lung Cellular and Molecular Physiology, 285(4), L802–807. PMID: 12704019.

Correa-Meyer, E., Pesce, L., Guerrero, C. & Sznajder, J. I. (2002). Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells. (Vols. 282). (5), pp. L883-91. Am J Physiol Lung Cell Mol Physiol.

Guerrero, C., Pesce, L., Lecuona, E., Ridge, K. M. & Sznajder, J. I. (2002). Dopamine activates ERKs in alveolar epithelial cells via Ras-PKC-dependent and Grb2/Sos-independent mechanisms. (Vols. 282). (5), pp. L1099-107. Am J Physiol Lung Cell Mol Physiol.

Cajigas, H. E., Lecuona, E., Dada, L., Pesce, L., Ridge, K. M., Chandel, N. & Sznajder, J. I. (2002). Hypoxia decreases E-cadherin at the plasma level of lung carcinoma cells. (Vols. 165). (A370) American Journal of Respiratory and Critical Care Medicine.

Pesce, L., Budinger, S., Strous, G., Chandel, N., Ciechanover, A. & Sznajder, J. I. (2002). Hypoxia induces Na,K-ATPase degradation via ubiquitin proteasome/lysosome pathways. (Vols. 165). (A518) American Journal of Respiratory and Critical Care Medicine.

Correa-Meyer, E., Pesce, L., Guerrero, C. & Sznajder, J. I. (2001). Activation of extracellular signal-regulated kinases ½ by cyclic stretch of alveolar epithelial cells via G-proteins and epidermal growth factor receptor. (Vols. 163). (A460) American Journal of Respiratory and Critical Care Medicine.

Lecuona, E., Vena, R., Pesce, L. & Sznajder, J. I. (2001). Beta-adrenergic agonists regulate the Na,K-ATPase via RhoA. (Vols. 163). (A570) American Journal of Respiratory and Critical Care Medicine.

Adir, Y., Azzam, Z., Leal, S., Ridge, K. M., Pesce, L., Young, J. B. & Sznajder, J. I. (2001). Enriched tyrosine diet increases alveolar fluid reabsorption. (Vols. 163). (A451) American Journal of Respiratory and Critical Care Medicine.

Upadhyay, D., Correa-Meyer, E., Pesce, L. & Kamp, D. W. (2001). FGF-10 attenuates H2O2-induced alveolar epithelial cell damage and cell death via mitogen activated protein kinases pathways. (Vols. 163). (A793) American Journal of Respiratory and Critical Care Medicine.

Pesce, L., Guerrero, C., Comellas, A., Ridge, K. M. & Sznajder, J. I. (2000). beta-agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways. (Vols. 486). (3), pp. 310-4. FEBS Lett.

Friedman, E., Novoa, E., Crespo, A., Marcano, H., Pesce, L., Comellas, A. & Sanchez de Leon, R. (2000). Effect of hydrocortisone on platelet activating factor induced lung edema in isolated rabbit lungs. (Vols. 120). (1), pp. 61-9. Respir Physiol.

Correa Meyer, E., Pesce, L., Guerrero, C. & Sznajder, J. I. (2000). Cyclic stretch activates MAPK/ERK pathway in rat alveolar epitelial type II cells. (Vols. 118). (155S) CHEST.

Upadhyay, D., Meyer, E. C., Pesce, L. & Kamp, D. W. (2000). FGF-10 attenuates H2O2-induced DNA damage in alveolar epithelial cells via activation of signaling pathways. (Vols. 118). (156S) CHEST.

Comellas, A., Pesce, L., Azzam, Z., Saldias, F. & Sznajder, J. I. (2000). Scorpion (Tityus serrulatus) venom decreases alveolar fluid reabsorption in rat lungs. (Vols. 161). (A99) American Journal of Respiratory and Critical Care Medicine.

Comellas, A., Tristano, S., Pesce, L., Friedman, E., Marcano, H. & Sanchez de Leon, R. (1999). Effect of platelet activating factor (PAF) on pulmonary circulation in isolated rabbit lung. (Vols. 55). (1), pp. 1-6. J Physiol Biochem.

D'Suze, G., Comellas, A., Pesce, L., Sevcik, C. & Sanchez de Leon, R. (1999). Tityus discrepans venom produces a respiratory distress syndrome in rabbits through an indirect mechanism. (Vols. 37). (1), pp. 173-80. Toxicon.

Pesce, L., Tristano, S., Friedman, E., Comellas, A., Marcano, H. & Sanchez de Leon, R. (1998). Effect of Fenoterol on PAF-induced lung edema in isolated and perfused rabbit lungs. (Vols. 114). (2), pp. 153-60. Respir Physiol.

Pesce, L., Guerrero, C., Correa-Meyer, E., Ridge, K. & Sznajder, J. I. Post-transcriptional regulation of Na, K-ATPase by adrenergic agonists via MAPK/ERK in alveolar epithelial cells. (Vols. 161). pp. A24. American Journal of Respiratory and Critical Care Medicine.