M. Sue O'Dorisio, MD, PhD

Portrait
Pediatric Hematology/Oncology Fellowship Director
Professor of Pediatrics - Hematology Oncology

Contact Information

Primary Office
3080 ML
Iowa City, IA 52242
319-356-7873

Education

BS, Mathematics, cum laude, Creighton University, Omaha, Nebraska
MS, Biochemistry, cum laude, University of Nebraska, Omaha, Nebraska
PhD, Biochemistry, cum laude, University of Nebraska, Omaha, Nebraska
MD, Medicine, cum laude, Ohio State University, Columbus, Ohio
Fellow, Biochemistry, Ohio State University, Columbus, Ohio
Fellow, Medicine, Ohio State University, Columbus, Ohio
Medicine, The Ohio State University
Resident, Pediatrics, Ohio State University, Columbus, Ohio
Fellow, Hematology/Oncology, Ohio State University, Columbus, Ohio

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Neuroscience, Interdisciplinary Graduate Program in Translational Biomedicine, Medical Scientist Training Program

Research Summary

Role of neuropeptides in development of neural crest derivatives.

Nervous system tumors are the most common cause of death from pediatric malignancies and rank second only to accidents as a cause of death in this age group. These cancers arise in the developing nervous system during fetal growth or infancy. Neuropeptides are important modulators of neurodevelopment and provide neuroprotection for stem cells and neurons. Vasoactive intestinal peptide is both a differentiation factor and a neuroprotective agent. Somatostatin is a potent modulator of growth factor release and also modulates the signal transduction pathway for multiple growth factors. We are studying the role of vasoactive intestinal peptide and somatostatin in neural development using transgenic and knock out mice. This new understanding of the role of neuropeptides in neural crest development should allow us to develop new diagnostic and therapeutic options for children with neuroblastoma and medulloblastoma.

Publications

Madsen, M. T., Menda, Y., O'Dorisio, T. M. & O'Dorisio, M. S. (2018). Technical Note: Single time point dose estimate for exponential clearance. Medical physics, 45(5), 2318-2324. PMID: 29577338.

Menda, Y., Madsen, M. T., O'Dorisio, T. M., Sunderland, J., Watkins, L. G., Dillon, J. S., Mott, S. L., Schultz, M. K., Zamba GKD,, Bushnell, D. L. & O'Dorisio, M. S. (2018). 90Y-DOTATOC Dosimetry-Based Personalized Peptide Receptor Radionuclide Therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. PMID: 29523629.

Hope, T. A., Bergsland, E. K., Bozkurt, M. F., Graham, M., Heaney, A. P., Herrmann, K., Howe, J. R., Kulke, M. H., Kunz, P. L., Mailman, J., May, L., Metz, D. C., Millo, C., O'Dorisio, S., Reidy-Lagunes, D. L., Soulen, M. C. & Strosberg, J. R. (2018). Appropriate Use Criteria for Somatostatin Receptor PET Imaging in Neuroendocrine Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 59(1), 66-74. PMID: 29025982.

Abongwa, C., Mott, S., Schafer, B., McNeely, P., Abusin, G., O'Dorisio, T., Zamba, G., O'Dorisio, M. S. & Menda, Y. (2017). Safety and accuracy of 68Ga-DOTATOC PET/CT in children and young adults with solid tumors. American journal of nuclear medicine and molecular imaging, 7(5), 228-235. PMID: 29181270.

Menda, Y., O'Dorisio, T. M., Howe, J. R., Schultz, M., Dillon, J. S., Dick, D., Watkins, G. L., Ginader, T., Bushnell, D. L., Sunderland, J. J., Zamba GKD,, Graham, M. & O'Dorisio, M. S. (2017). Localization of Unknown Primary Site with 68Ga-DOTATOC PET/CT in Patients with Metastatic Neuroendocrine Tumor. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 58(7), 1054-1057. PMID: 28153957.

Sharma, N., Naraev, B. G., Engelman, E. G., Zimmerman, M. B., Bushnell, Jr, D. L., O'Dorisio, T. M., O'Dorisio, M. S., Menda, Y., Müller-Brand, J., Howe, J. R. & Halfdanarson, T. R. (2017). Peptide Receptor Radionuclide Therapy Outcomes in a North American Cohort With Metastatic Well-Differentiated Neuroendocrine Tumors. Pancreas, 46(2), 151-156. PMID: 27759712.

Abad, C., Jayaram, B., Becquet, L., Wang, Y., O’Dorisio, M. S., Waschek, J. A. & Tan, Y. (2016). VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage. Journal of Neuroinflammation, 13(1), 169. PMID: 27357191.

Bushnell, D. L., Madsen, M. T., O'cdorisio, T., Menda, Y., Muzahir, S., Ryan, R. & O'dorisio, M. S. (2014). Feasibility and advantage of adding (131)I-MIBG to (90)Y-DOTATOC for treatment of patients with advanced stage neuroendocrine tumors. EJNMMI research, 4(1), 38. PMID: 26116109.

Sherman, S. K., Maxwell, J. E., Carr, J. C., Wang, D., Bellizzi, A. M., Sue O'Dorisio, M., O'Dorisio, T. M. & Howe, J. R. (2014). Gene expression accurately distinguishes liver metastases of small bowel and pancreas neuroendocrine tumors. Clinical & experimental metastasis, 31(8), 935-44. PMID: 25241033.

Maxwell, J. E., Sherman, S. K., Stashek, K. M., O’Dorisio, T. M., Bellizzi, A. M. & Howe, J. R. (2014). A practical method to determine the site of unknown primary in metastatic neuroendocrine tumors. Surgery, 156(6), 1359–1366. DOI: 10.1016/j.surg.2014.08.008.

Sherman, S. K., Maxwell, J. E., O'Dorisio, M. S., O'Dorisio, T. M. & Howe, J. R. (2014). Pancreastatin predicts survival in neuroendocrine tumors. Annals of surgical oncology, 21(9), 2971-80. PMID: 24752611.

Sherman, S. K., Maxwell, J. E., Carr, J. C., Wang, D., O'Dorisio, M. S., O'Dorisio, T. M. & Howe, J. R. (2014). GIPR expression in gastric and duodenal neuroendocrine tumors. The Journal of surgical research, 190(2), 587-93. PMID: 24565507.

Chen, J. J., Kamberos, N. L., O'Dorisio, M. S., Syed, N. A. & Boldt, C. (2014). Choroidal schwannoma in a 6-month-old girl. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, 18(2), 197-9. PMID: 24698624.

Bodei, L., Mueller-Brand, J., Baum, R. P., Pavel, M. E., Hörsch, D., O’Dorisio, M. S., O’Dorisio, T. M., Howe, J. R., Cremonesi, M., Kwekkeboom, D. J. & Zaknun, J. J. (2014). Erratum: The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours (Eur J Nucl Med Mol Imaging DOI 10.1007/s00259-012-2330-6). European Journal of Nuclear Medicine and Molecular Imaging, 41(3), 584. DOI: 10.1007/s00259-013-2454-3.

Sherman, S. K., Carr, J. C., Wang, D., O'Dorisio, M. S., O'Dorisio, T. M. & Howe, J. R. (2013). Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in neuroendocrine tumors. Surgery, 154(6), 1206-13; discussion 1214. PMID: 24238043.

Carr, J. C., Sherman, S. K., Wang, D., Dahdaleh, F. S., Bellizzi, A. M., O’Dorisio, M. S., O’Dorisio, T. M. & Howe, J. R. (2013). Overexpression of membrane proteins in primary and metastatic gastrointestinal neuroendocrine tumors. Annals of Surgical Oncology, 20 Suppl 3, S739–746. PMID: 24114056.

Whittier, K. L., Boese, E. A., Gibson-Corley, K. N., Kirby, P. A., Darbro, B. W., Qian, Q., Ingram, W. J., Robertson, T., Remke, M., Taylor, M. D. & O'Dorisio, M. S. (2013). G-protein coupled receptor expression patterns delineate medulloblastoma subgroups. Acta neuropathologica communications, 1, 66. PMID: 24252460.

Menda, Y., Ponto, L. L., Schultz, M. K., Zamba, G. K., Watkins, G. L., Bushnell, D. L., Madsen, M. T., Sunderland, J. J., Graham, M. M., O’Dorisio, T. M. & O’Dorisio, M. S. (2013). Repeatability of gallium-68 DOTATOC positron emission tomographic imaging in neuroendocrine tumors. Pancreas, 42(6), 937–943. PMID: 23587853.

Bodei, L., Baum, R., Bahl, A., Kwekkeboom, D., Pavel, M., Hirsch, D., O'Dorisio, T., O'Dorisio, M. S. & Zakun, J. (2013). Guidelines for the use of Peptide Receptor Radionuclide Therapy. Eur J Nucl Med Mol Imaging, 40(5), 800-16. PMID: 23389427.

Zaknun, J. J., Agency, I. A. (2013). Practical guidance on peptide receptor radionuclide therapy (PRRNT) for neuroendocrine tumors. (20) Vienna: International Atomic Energy Agency.

Zaknun, J. J., Bodei, L., Mueller-Brand, J., Pavel, M. E., Baum, R. P., Hörsch, D., O’Dorisio, M. S., O'Dorisio, T. M., Howe, J. R., Cremonesi, M. & Kwekkeboom, D. J. (2013). The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours. European Journal of Nuclear Medicine and Molecular Imaging, 40(5), 800-816. DOI: 10.1007/s00259-012-2330-6.

Martin, M. E., O'Dorisio, M., Leverich, W., Kloepping, K. C. & Schultz, M. K. (2013). “Click” cyclized gallium-68 labeled peptides for molecular imaging and therapy: Synthesis and preliminary in vitro and in vivo evaluation in a melanoma model system. Recent Results in Cancer Research, 194, 149-175. PMID: 22918759.

O'Dorisio, M., Howell, D. L. (2012). Management of neuroendocrine tumors in children, adolescents, and young adults. J Pediatr Hematol Oncol, 34(2), S64-8. PMID: 22525409.

Carr, J. C., Boese, A. E., Spanheimer, P. E., Dahdaleh, F. S., Martin, M. E., Calva, D., Schafer, B., Thole, D. M., Braun, T., O’Dorisio, T. M., O'Dorisio, M. & Howe, J. R. (2012). Differentiation of small bowel and pancreatic neuroendocrine tumors by gene expression profiling. Surgery.

Baumhover, N. J., Martin, M. E., Parameswarappa, G., Kloepping, K. C., O'Dorisio, M., Pigge, F. C. & Schultz, M. K. (2011). Improved synthesis and biological evaluation of chelator-modified a-MSH analogs prepared by copper-free click chemistry. Bioorg Med Chem Lett, 21, 5757-61. PMID: 21873053.

Fabricius, D., Karacay, B., Shutt, D., Leverich, W., Schafer, B., Takle, E., Thedens, D., Khanna, G., Raikwar, S., Yang, B., Desmond, M. E. & O'Dorisio, M. (2011). Characterization of intestinal and pancreatic dysfunction in VPAC1-null mutant mouse. Pancreas, 40, 861-71. PMID: 21697765.

Sarvida, M. E., O'Dorisio, M. (2011). Neuroendocrine tumors in children and young adults: rare or not so rare. Endocrinol Metab Clin North Am, 40(1), 65-80. PMID: 21349411.

Navalkele, P., O'Dorisio, M., O’Dorisio, T. M., Zamba, G. K. & Lynch, C. F. (2011). Incidence, Survival and Prevalence of Neuroendocrine Tumors versus Neuroblastoma in Children and Young Adults: Nine Standard SEER Registries, 1975-2006. Pediatric Blood and Cancer, 56, 50-7. PMID: 21108439.

Menda, Y., O’Dorisio, M. S., Kao, S., Khanna, G., Michael, S., Connolly, M., Babich, J., O’Dorisio, T., Bushnell, D. & Madsen, M. (2010). Phase I trial of 90Y-DOTATOC therapy in children and young adults with refractory solid tumors that express somatostatin receptors. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 51(10), 1524–1531. PMID: 20847174.

Martin, M. E., Parameswarappa, S. G., O'Dorisio, M., Pigge, F. C. & Schultz, M. K. (2010). A DOTA-peptide conjugate by copper-free click chemistry. Bioorg Med Chem Lett, 20(16), 4805-7. PMID: 20630750.

Chen, H., Sippel, R. S., O'Dorisio, M., Vinik, A. I., Lloyd, R. V. & Pacak, K. (2010). The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer. Pancreas, 39(6), 775-83. PMID: 20664475.

O'Dorisio, T. M., Krutzik, S. R., Woltering, E. A., Lindholm, E., Joseph, S., Gandolfi, A. E., Wang, Y. Z., Boudreaux, J. P., Vinik, A. I., Go, V. L., Howe, J. R., Halfdanarson, T., O'Dorisio, M. & Mamikunian, G. (2010). Development of a Highly Sensitive and Specific Carboxy-Terminal Human Pancreastatin Assay to Monitor Neuroendocrine Tumor Behavior. Pancreas, 39, 611-6. PMID: 20124939.

Shutt, D. C., O'Dorisio, M., Aykin-Burns, N. & Spitz, D. R. (2010). 2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cells. Cancer Biol Ther, 9, 853-61. PMID: 20364116.

Bushnell, D., O’Dorisio, T. M. & O'Dorisio, M. (2010). 90Y-Edotreotide for Metastatic Carcinoid Refractory to Octreotide. J Clin Oncol, 28, 1652-9. PMID: 20194865.

Calva, D., O’Dorisio, T., O’Dorisio, M. S., Lal, G., Sugg, S., Weigel, R. & Howe, J. (2010). Reply to, "RET germline mutations in codon 609 and MEN2A phenotype: Are they all created equal?" by Machens and Dralle (ASO-2009-06-0652). Annals of Surgical Oncology, 17(1), 333. DOI: 10.1245/s10434-009-0753-5.

Calva, D., O'Dorisio, T. M., O'Dorisio, M., Lal, G., Sugg, S., Weigel, R. J. & Howe, J. R. (2009). When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?. Ann Surg Oncol, 16(8), 2237-44.

Nam, C., Case, A. J., Hostager, B. S. & O’Dorisio, M. S. (2009). The role of vasoactive intestinal peptide (VIP) in megakaryocyte proliferation. Journal of molecular neuroscience: MN, 37(2), 160–167. PMID: 18663606.

O'Dorisio, M. (2009). Neuroendocrine Tumors in Children and Young Adults. In G. Mamikunian , A. Vinik , T. M. O’Dorisio , E. A. Woltering , V. L. Go (Eds.) Neuroendocrine Tumors. Interscience Institute.

Nam, C. E., Case, A., Hostager, B. & O'Dorisio, M. (2009). The role of vasoactive intestinal peptide (VIP) in Megakaryocyte proliferation and platelet formation. J Molec Neuroscience, 37, 160-162.

Wiseman, G. A., Pacak, K., O’Dorisio, M., Neumann, D. R., Waxman, A. D., Mankoff, D. A., Heiba, S. I., Serafini, A. N., Tumeh, S. S., Khutoryansky, N. & Jacobson, A. F. (2009). Usefulness of123I-MIBG scintigraphy in the evaluation of patients with known or suspected primary or metastatic pheochromocytoma or paraganglioma: Results from a prospective multicenter trial. Journal of Nuclear Medicine, 50(9), 1448-1454. DOI: 10.2967/jnumed.108.058701.

O’Dorisio, M. S., Khanna, G. & Bushnell, D. (2008). Combining anatomic and molecularly targeted imaging in the diagnosis and surveillance of embryonal tumors of the nervous and endocrine systems in children. Cancer Metastasis Reviews, 27(4), 665–677. PMID: 18581060.

Lal, G., Padmanabha, L., Nicholson, R., Smith, B. J., Zhang, L., Howe, J. R., Robinson, R. A. & O’Dorisio, M. S. (2008). ECM1 expression in thyroid tumors–a comparison of real-time RT-PCR and IHC. The Journal of Surgical Research, 149(1), 62–68. PMID: 18374945.

Khanna, G., Bushnell, D. & O'Dorisio, M. (2008). Utility of radiolabeled somatostatin-receptor analogues for staging/restaging and treatment of somatostatin receptor positive pediatric tumors. Oncologist, 13(4), 382-9.

Khanna, G., O'Dorisio, M., Menda, Y., Kirby, P., Kao, S. C. & Sato, Y. (2008). Gastroenteropancreatic Neuroendocrine Tumors in Children and Young Adults. Pediatric Radiology, 38(3), 251-9.

Khanna, G., O’Dorisio, M. S., Menda, Y., Glasier, C., Deyoung, B., Smith, B. J., Graham, M. & Juweid, M. (2008). Somatostatin receptor scintigraphy in surveillance of pediatric brain malignancies. Pediatric Blood & Cancer, 50(3), 561–566. PMID: 17387742.

O'Dorisio, M., Khanna, G. & Bushnell, D. (2008). Image Guided Therapy in Pediatric Malignancies. Cancer and Metastasis Reviews, 13, 382-389.

Vaidyanathan, G., Affleck, D., Norman, J., O'Dorisio, M. & Zalutsky, M. (2007). A Radioiodinated MIBG-octreotate Conjugate Exhibiting Enhanced Uptake and Retention in SSTR2 Expressing Tumor Cells. BioConjugate Chemistry, 18(6), 2122-30.

O’Dorisio, N. J., O'Dorisio, M. & O’Dorisio, T. M. (2007). The Significance of Functional Imaging in the Diagnosis and Surveillance of Neuroendocrine Tumors. In Medscape. WebMD.

Fabricius, D., O’Dorisio, M. S., Blackwell, S. & Jahrsdörfer, B. (2006). Human plasmacytoid dendritic cell function: inhibition of IFN-alpha secretion and modulation of immune phenotype by vasoactive intestinal peptide. Journal of Immunology (Baltimore, Md.: 1950), 177(9), 5920–5927. PMID: 17056516.

Madsen, M. T., Bushnell, D. L., Juweid, M. E., Menda, Y., O’Dorisio, M. S., O’Dorisio, T. & Besse, I. M. (2006). Potential increased tumor-dose delivery with combined 131I-MIBG and 90Y-DOTATOC treatment in neuroendocrine tumors: a theoretic model. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 47(4), 660–667. PMID: 16595501.

Miller, M. A., Karacay, B., Zhu, X., O'Dorisio, M. & Sandler, A. D. (2006). Caspase 8L, a novel inhibitory isoform of caspase 8, is associated with undifferentiated neuroblastoma. (Vols. 11). (1), pp. 15-24. Apoptosis.

O’Dorisio, N. J., O'Dorisio, M. & O’Dorisio, T. M. (2006). Evidence-based Diagnosis and Treatment of Neuroendocrine Tumors. In P. M. Camacho , H. Charib & G. W. Sizemore (Eds.) Evidence-based Endocrinology. pp. 243-248. Lippencott Williams Wilkins.

Gunn, S. H., Schwimer, J. E., Cox, M. O., Anthony, C. T., O'Dorisio, M. & Woltering, E. A. (2006). In vitro modeling of the clinical interactions between Octreotide and 111In-Pentetreotide: Is there evidence of somatostatin receptor downregulation?. (Vols. 47). (2), pp. 354-359. J. Nucl Med.

Lal, G., Padmanabha, L., Smith, B. J., Nicholson, R. M., Howe, J. R., O'Dorisio, M. & Domann Jr., F. E. (2006). RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma. Cancer, 107, 2752-2758.

Howes, T. L., Buatti, J. M., O’Dorisio, M. S., Kirby, P. A. & Ryken, T. C. (2005). Atypical teratoid/rhabdoid tumor case report: treatment with surgical excision, radiation therapy, and alternative medicines. Journal of Neuro-Oncology, 72(1), 85–88. PMID: 15803380.

Hoffman, W. H., Jueppner, H. W., DeYoung, B. R., O'Dorisio, M. & Given, K. S. (2005). Elevated fibroblast growth factor-23 in hypophosphatemic linear nevus sebaceous syndrome. (Vols. 134A). (3), pp. 233-236. Am J Med Genet A.

Pashankar, F. D., O’Dorisio, M. S. & Menda, Y. (2005). MIBG and somatostatin receptor analogs in children: current concepts on diagnostic and therapeutic use. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 46 Suppl 1, 55S–61S. PMID: 15653652.

Miller, M. A., Karacay, B., Brewlow, N., Li, S., O'Dorisio, M., Grundy, P. E. & Sandler, A. D. (2005). Prognostic value of quantifying apoptosis factor expression in favorable histology Wilms tumors. (Vols. 1). (11-14) J Pediatr Hematol Oncol.

Bushnell, D., Menda, Y., O’Dorisio, T., Madsen, M., Miller, S., Carlisle, T., Squires, S., Kahn, D., Walkner, W., Connolly, M., O’Dorisio, S., Karwal, M., Ponto, J. & Bouterfa, H. (2004). Effects of Intravenous Amino Acid Administration with Y-90 DOTA-Phe1-Tyr3-Octreotide (SMT487 [OctreoTher™]) Treatment. Cancer Biotherapy and Radiopharmaceuticals, 19(1), 35-41. DOI: 10.1089/108497804773391658.

Sall, J. W., Klisovic, D. D. & O'Dorisio, M. (2004). Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial cells. (Vols. 79). (4), pp. 465-476. Experimental Eye Research.

Frühwald, M. C., Rickert, C. H., O'Dorisio, M., Madsen, M., Warmuth-Metz, M., Khanna, G., Paulus, W., Kühl, J., Jürgens, H., Schneider, P. & Müller, H. L. (2004). Somatostatin receptor subtype 2 is expressed by supratentorial primitive neuroectodermal tumors of childhood and can be targeted for somatostatin receptor imaging. (Vols. 10). pp. 2997-3006. Clinical Cancer Research.

Summers, M. A., O’Dorisio, M. S., Cox, M. O., Lara-Marquez, M. & Goetzl, E. J. (2003). A lymphocyte-generated fragment of vasoactive intestinal peptide with VPAC1 agonist activity and VPAC2 antagonist effects. The Journal of Pharmacology and Experimental Therapeutics, 306(2), 638–645. PMID: 12750439.

Summers, M. A., O'Dorisio, M., Cox, M. O., Lara-Marquez, M. & Goetzl, E. (2003). A lymphocyte generated fragment of vasoactive intestinal peptide with agonist activity for VIP receptor 1 and antagonist effects on VIP receptor 2. (Vols. 308). pp. 1-6. Journal of Pharmacology and Experimental Therapeutics.

Cooke, H. J., Wang, Y. Z., Wray, D., O'Dorisio, M., Woltering, E. A., Coy, D. H., Murphy, W. A., Christofi, F. L., Gosh, P. & O’Dorisio, T. M. (2003). A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon. (Vols. 114). (1), pp. 51-60. Regulatory Peptides.

Cooke, H. J., Wang, Y. Z., Wray, D., O’Dorisio, M. S., Woltering, E. A., Coy, D. H., Murphy, W. A., Christofi, F. L., Gosh, P. & O’Dorisio, T. M. (2003). Erratum: A multi-tyrosinated sst1/2 receptor preferring somatostatin agonist inhibits reflex and immune-mediated secretion in the guinea pig colon (Regulatory Peptides (2003) 114 (51-60)). Regulatory Peptides, 115(2), 151. DOI: 10.1016/S0167-0115(03)00188-5.

O'Dorisio, M., O’Dorisio, T. M. (2003). Two-Career Families: Published Data and Personal Reflections. Exp BiolMed (Maywood), 228(11), 1266-1268.

O'Dorisio, M., Karacay, B. (2003). Vasoactive Intestinal Peptide (VIP): Neurotransmitters, Hormone and Cytokine. In H. Henry , A. Norman (Eds.) Encyclopedia of Hormones. Elsevier.

Karacay, B., O'Dorisio, M., Summers, M., Robinson, M. & Bonthius, D. J. (2003). VIP receptor 1 (VPAC1) promoter targets the expression of a reporter gene to cerebellum and adrenal medulla in transgenic mice. (Vols. 116). pp. 1-12. Regulatory Peptides.

Juweid, M. E., Menda, Y., O’Dorisio, M. S., Bushnell, D., Blake, M., Madsen, M., Johnson, J. & Graham, M. M. (2002). 111In-pentetreotide versus bone scintigraphy in the detection of bony metastases of neuroblastoma. Nuclear Medicine Communications, 23(10), 983-989. DOI: 10.1097/00006231-200210000-00008.

O'Dorisio, M., Hauger, M. & O’Dorisio, T. M. (2002). Age-dependent levels of plasma neuropeptides in normal children. (Vols. 109). (1-3), pp. 189-192. Regulatory Peptides.

Katz, S. E., Klisovic, D. D., O'Dorisio, M., Lynch, R. & Lubow, M. (2002). Expression of somatostatin receptors 1 and 2 in human choroid plexus and arachnoid granulations. (Vols. 120). pp. 1540-1543. Arch Ophthalmol.

Lee, A. G., O’Dorisio, M. S. (2002). Nitrosourea-based chemotherapy in optic pathway glioma with progressive visual loss. Neuro-Ophthalmology, 28(2), 107-115. DOI: 10.1076/noph.28.2.107.23743.

Balster, D. A., O'Dorisio, M., Albers, A. R., Park, S. K. & Qualman, S. J. (2002). Suppression of tumorigenicity in neuroblastoma cells by upregulation of human vasoactive intestinal peptide receptor type 1. (Vols. 109). (1-3), pp. 155-165. Regulatory Peptides.

Sandler, A., Scott, D., Azuhata, T., Takamizawa, S. & O’Dorisio, S. (2002). The survivin:Fas ratio is predictive of recurrent disease in neuroblastoma. Journal of Pediatric Surgery, 37(3), 507-511. DOI: 10.1053/jpsu.2002.30857.

Frühwald, M. C., O'Dorisio, M., Dai, Z., Rush, L. J., Krahe, R., Smiraglia, D. J., Pietsch, T., Elsea, S. H. & Plass, C. (2001). Aberrant hypermethylation of the major breakpoint cluster region in 17p11.2 in medulloblastomas but not supratentorial PNETs. (Vols. 30). pp. 38-47. Genes Chromosom Cancer.

Frühwald, M. C., O’Dorisio, M. S., Dai, Z., Tanner, S. M., Balster, D. A., Gao, X., Wright, F. A. & Plass, C. (2001). Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas-Implications for tumor biology and potential clinical utility. Oncogene, 20(36), 5033-5042. DOI: 10.1038/sj.onc.1204613.

Lum, S. S., Fletcher, W. S., O'Dorisio, M., Nance, R. W., Pommier, R. F. & Caprara, M. (2001). Distribution and functional significance of somatostatin receptors in malignant melanoma. World J Surg, 25, 407-412.

Karacay, B., O'Dorisio, M., Kasow, K., Hollenback, C. & Krahe, R. (2001). Expression and fine mapping of murine vasoactive intestinal peptide receptor 1. J Mol Neurosci, 17, 311-324.

Watson, J. C., Balster, D. A., Gebhardt, B. M., O'Dorisio, T. M., O'Dorisio, M., Espenan, G. D., Drouant, G. J. & Woltering, E. A. (2001). Growing vascular endothelial cells express somatostatin subtype 2 receptors. Br J Cancer, 85(2), 266-272.

Frühwald, M. C., O’Dorisio, M. S., Smith, L., Dai, Z., Wright, F. A., Paulus, W., Jürgens, H. & Plass, C. (2001). Hypermethylation as a potential prognostic factor and a clue to a better understanding of the molecular pathogenesis of medulloblastoma - Results of a genomewide methylation scan. Klinische Padiatrie, 213(4), 197-203. DOI: 10.1055/s-2001-16851.

Balster, D. A., O'Dorisio, M., Summers, M. A. & Turman, M. A. (2001). Segmental expression of somatostatin receptor subtypes sst(1) and sst(2) in tubules and glomeruli of human kidney. Am J Physiol Renal PhysioL, 280(3), F457-F465.

Lara, M. L., O'Dorisio, M., O'Dorisio, T. M., Shah, M. H. & Karacay, B. (2001). Selective gene expression and activation-dependent regulation of vasoactive intestinal peptide receptor type 1 (VPAC1) and type 2 (VPAC2) in human T cells. J Immunol, 166, 2522-2530.

Lara-Marquez, M. L., O’Dorisio, M. S., O’Dorisio, T. M., Shah, M. H. & Karacay, B. (2001). Selective gene expression and activation-dependent regulation of vasoactive intestinal peptide receptor type 1 and type 2 in human T cells. Journal of Immunology, 166(4), 2522-2530.

Klisovic, D. D., Sall, J. W., O'Dorisio, M., Balster, D., O'Dorisio, T. M., Craig, E., Lubow, M. & Katz, S. E. (2001). Somatostatin receptor (SSTR) gene expression in human ocular tissues: RT-PCR and immunohistochemical study. (Vols. 42). (10), pp. 2193-2201. Invest Ophthalmol Vis Sci.

Klisovic, D. D., O’Dorisio, M. S., Katz, S. E., Sall, J. W., Balster, D., O’Dorisio, T. M., Craig, E. & Lubow, M. (2001). Somatostatin receptor gene expression in human ocular tissues: RT-PCR and immunohistochemical study. Investigative Ophthalmology and Visual Science, 42(10), 2193-2201.

Costello, J. F., Frühwald, M. C., Smiraglia, D. J., Rush, L. J., Robertson, G. P., Gao, X., Wright, F. A., Feramisco, J. D., Peltomäki, P., Lang, J. C., Schuller, D. E., Yu, L., Bloomfield, C. D., Caligiuri, M. A., Yates, A., Nishikawa, R., Su Huang, H. J., Petrelli, N. J., Zhang, X., O’Dorisio, M. S., Held, W. A., Cavenee, W. K. & Plass, C. (2000). Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nature Genetics, 24(2), 132-138. DOI: 10.1038/72785.

Frühwald, M. C., O'Dorisio, M., Rush, L. J., Reiter, J. L., Smiraglia, D. J., Wenger, G., Costello, J. F., White, P. S., Krahe, R., Brodeur, G. M. & Plass, C. (2000). Gene amplification in PNETs/medulloblastoma: mapping of a novel amplified gene within the MYCN amplicon. (Vols. 37). pp. 501-509. J Medical Genetics.

Karacay, B., O’Dorisio, M. S., Summers, M. & Bruce, J. (2000). Regulation of vasoactive intestinal peptide receptor expression in developing nervous systems. Annals of the New York Academy of Sciences, 921, 165-174.

Albers, A. R., O'Dorisio, M., Balster, D. A., Caprara, M., Gosh, P., Chen, F., Hoeger, C., Rivier, J., Wenger, G. D., O’Dorisio, T. M. & Qualman, S. J. (2000). Somatostatin receptor gene expression in neuroblastoma. (Vols. 82). pp. 61-73. Regulatory Peptides.

Lara-Marquez, M. L., O'Dorisio, M. & Karacay, B. (2000). Vasoactive intestinal peptide (VIP) receptor type 2 (VPAC2) is the predominant receptor expressed in human thymocytes. (Vols. 9). pp. 45-54. Ann NY Acad Sci.

Lara-Marquez, M. L., O’Dorisio, M. S. & Karacay, B. (2000). Vasoactive intestinal peptide (VIP) receptor type 2 (VPAC2) is the predominant receptor expressed in human thymocytes. Annals of the New York Academy of Sciences, 921, 45-54.

Smiraglia, D. J., Frühwald, M. C., Costello, J. F., McCormick, S. P., Dai, Z., Peltomaki, P., O'Dorisio, M., Cavenee, W. K. & Plass, C. (1999). A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels. (Vols. 58). pp. 254-262. Genomics.

O'Dorisio, M., Sall, J. W. & O’Dorisio, T. M. (1999). Biology of Neuroendocrine Tumors. In S. W. Lamberts (Eds.) Biology of Neuroendocrine Tumors. pp. 117-131. Bioscientifica Ltd..

Frühwald, M. C., O’Dorisio, M. S., Pietsch, T. & Reubi, J. C. (1999). High expression of somatostatin receptor subtype 2 (sst2) in medulloblastoma: Implications for diagnosis and therapy. Pediatric Research, 45(5 I), 697-708.

Cuntz, M. C., Levine, E. A., O’Dorisio, T. M., Watson, J. C., Wray, D. A., Espenan, G. D., McKnight, C., Meier, R., Weber, L. J., Mera, R., O'Dorisio, M. & Woltering, E. A. (1999). Intraoperative gamma detection of 125I-lanreotide in women with primary breast cancer. (Vols. 6). pp. 367-372. Ann Surg Oncol.

O'Dorisio, M., Park, S. K. (1999). Neuroendocrine Immune Axis in the Intestine. In Gastrointestinal Endocrinology. pp. 265-297. The Humana Press Inc..

Frühwald, M. C., O'Dorisio, M., Pietsch, T. & Reubi, J. (1999). Somatostatin and somatostatin receptor expression in primitive neuroectodermal tumors of childhood. (Vols. 45). pp. 1-11. Pediatric Research.

Woltering, E. A., O'Dorisio, M., O’Dorisio, T. M., Chen, F., Murphy, W. & Coy, D. (1999). Synthesis and characterization of multiply-tyrosinated, multiply-iodinated somatostatin analogs. (Vols. 53). (20), pp. 201-213. J Peptide Research.

Frühwald, M. C., O'Dorisio, M., Fleitz, J., Summers, M. A., Pietsch, T. & Reubi, J. (1999). Vasoactive intestinal peptide (VIP) receptors: Gene expression and growth modulation in medulloblastoma and other central primitive neuroectodermal tumors of childhood. (Vols. 81). pp. 165-173. Int J Cancer.

Balster, D. A., O’Dorisio, M. S., Park, S. K. & Qualman, S. J. (1998). Human vasoactive intestinal peptide (VIP)1 receptor induces differentiation in neuroblastoma cells. FASEB Journal, 12(5).

Frühwald, M. C., O'Dorisio, M., Cottingham, S. L., Qualman, S. J. & O’Dorisio, T. M. (1998). Neuropeptides in developmental tumors of the central and peripheral nervous system. (Vols. 865). pp. 420-426. Ann NY Acad Sci.

Fletcher, W. S., Lum, S. S., Nance, R. W., Pommier, R. F. & O'Dorisio, M. (1998). The current status of somatostatin receptors in malignant melanoma. (Vols. 70). pp. 561-563. Yale J Biol Med.

Ellison, E. D., Schirmer, W. J., Olsen, J. O., Pozderac, R. V., Hinkle, G., Hill, T., O’Dorisio, T. M. & O'Dorisio, M. (1997). Localization of neuroendocrine tumors using somatostatin receptor imaging with indium-111-pentetreotide (octreoscan). (Vols. 4). pp. 35-39. Cancer Control.

Turman, M. A., O'Dorisio, M., O’Dorisio, T. M., Apple, C. A. & Albers, A. R. (1997). Somatostatin expression in human renal cortex and mesangial cells. (Vols. 68). pp. 15-21. Regul Pept.

Park, S. K., Olson, T. A., Ercal, N., Summers, M. & O'Dorisio, M. (1996). Characterization of vasoactive intestinal peptide receptors on human megakaryocytes and platelets. (Vols. 87). pp. 4629-4635. Blood.

O'Dorisio, M., Albers, A. R. (1996). Clinical use of somatostatin analogues in paediatric oncology. Digestion, 57(1), 38-41.

Martinez, D. A., Kahwash, S., O'Dorisio, M., Lloyd, T. V., McGhee, R. B., Morris, J. D. & Qualman, S. J. (1996). Disseminated neuroblastoma in the nude rat: A xenograft model of human malignancy. (Vols. 77). pp. 409-419. Cancer.

Fisher, W. E., Muscarella, P., O’Dorisio, T. M., O'Dorisio, M., Kim, J. A., Doran, T. A., Sabourin, C. L. & Schirmer, W. J. (1996). Expression of the somatostatin receptor subtype-2 gene predicts response of human pancreatic cancer to octreotide. (Vols. 120). pp. 234-241. Surgery.

O'Dorisio, M. (1996). The application of receptor biology to the diagnosis and management of cancer. TeleLecture Clinics: Peptide Therapy, 3, 10-11.

Park, S. K., O'Dorisio, M. & O’Dorisio, T. M. (1996). Vasoactive intestinal polypeptide-secreting tumours: biology and therapy. In D. O’Shea , S. R. Bloom (Eds.) Baillieres Clinical Gastroenterology. pp. 673-696. Bailliere Tindall.

Sirinek, L. P., O'Dorisio, M. & Dunaway, D. J. (1995). Accumulation of donor-specific cytotoxic T-cells in intestinal lymphoid tissues following intestinal transplantation. (Vols. 15). pp. 258-265. J Clin Immunol.

O'Dorisio, M., O’Dorisio, T. M. (1995). Clinical and therapeutic implications of gastrointestinal peptides and their analogs. New Perspectives in Cancer Diagnosis and Management, 3, 2.

O'Dorisio, M., Broner, C. W., Rosenberg, R. B. & O'Dorisio, T. M. (1995). Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia. (Vols. 309). pp. 1-11. The American Journal of the Medical Sciences.

Hynds, D. L., Summers, M., Van Brocklyn, J., O'Dorisio, M. & Yates, A. (1995). Gangliosides inhibit platelet-derived growth factor stimulated growth, receptor phosphorylation and dimerization in neuroblastoma SH-SY5Y cells. (Vols. 65). pp. 2251-2258. J Neurochem.

Fisher, W. E., Boros, L. G., O’Dorisio, T. M., O'Dorisio, M. & Schirmer, W. J. (1995). GI hormonal changes in diabetes influence pancreatic cancer growth. (Vols. 58). pp. 754-758. J Surg Res.

Martinez, D. A., O'Dorisio, M., O’Dorisio, T. M., Qualman, S. J., Caniano, D. A., Teich, S., Besner, G. E. & King, D. R. (1995). Intraoperative detection and resection of occult neuroblastoma: A technique exploiting somatostatin receptor expression. (Vols. 30). pp. 1580-1589. J Pediatr Surg.

Martinez, D. A., King, D., Romshe, C. A., Lozano, R. A., Morris, J. D., O'Dorisio, M. & Martin, E. A. (1995). Intraoperative identification of parathyroid adenomas: A new approach. (Vols. 30). pp. 1-5. J Ped Surg.

Martinez, D. A., King, D. R., Romshe, C., Lozano, R. A., Morris, J. D., O’Dorisio, M. S. & Martin, Jr., E. (1995). Intraoperative identification of parathyroid gland pathology: A new approach. Journal of Pediatric Surgery, 30(9), 1306-1309. DOI: 10.1016/0022-3468(95)90491-3.

Olsen, J. O., Pozderac, R. V., Hinkle, G., Hill, T., O’Dorisio, T. M., Schirmer, W. J., Ellison, E. C. & O'Dorisio, M. (1995). Somatostatin receptor imaging of neuroendocrine tumors with indium-111 pentetreotide (octreoscan). (Vols. 25). pp. 251-261. Semin Nucl Med.

Woltering, E. A., O'Dorisio, M. & O’Dorisio, T. M. (1995). The role of radiolabelled somatostatin analogs in the management of cancer patients. In V. T. DeVita , S. Hellman & S. A. Rosenberg (Eds.) Principles and Progress in Oncology: Updates. pp. 1-15. JB Lippincott.

O'Dorisio, M., Chen, F., O’Dorisio, T. M., Hauger, M. & Qualman, S. J. (1994). Characterization of somatostatin receptors in human neuroblastoma tumors. (Vols. 5). pp. 1-8. Cell Growth Differ.

O’Dorisio, M. S., Chen, F., O’Dorisio, T. M., Wray, D. & Qualman, S. J. (1994). Characterization of somatostatin receptors on human neuroblastoma tumors. Cell Growth and Differentiation, 5(1), 1-8.

Woltering, E. A., Barrie, R., O’Dorisio, T., O'Dorisio, M., Nance, R. & Cook, D. M. (1994). Detection of occult gastrinomas utilizing 125-I labeled somatuline and intraoperative gamma detection. (Vols. 116). pp. 1139-1146. Surgery.

Martinez, D. A., O'Dorisio, M., Orahood, R. C., Thurston, M. O., Martin, E. W., King, D. R., O’Dorisio, T. M., Hinkle, G. H. & Barnes, J. A. (1994). Future directions for the RIGS technology: Other cancer applications, targeting agents and instruments. In E. W. Martin Jr. (Eds.) Radioimmunoguided Surgery (RIGS) in the Detection and Treatment of Colorectal Cancer. pp. 171-185. R.G. Landes Company.

Schirmer, T. P., O’Dorisio, T. M., Olsen, J. O., Hinkle, G. H., O'Dorisio, M. & Schirmer, W. J. (1994). Influence of isotope dose on somatostatin receptor imaging: when less is better. Semin Oncol, 21, 51-55.

Rosenberg, R. B., Broner, C. W. & O'Dorisio, M. (1994). Modulation of cyclic guanosine monophosphate production during Escherichia coli septic shock. (Vols. 51). pp. 149-155. Biochem Med Metab Biol.

O’Dorisio, T. M., O'Dorisio, M. & Owyang, C. (1994). Rational and clinical application of neuropeptide congeners for diagnosis and therapy of neuroendocrine tumors. The Regulatory Peptide Letter, 5, 52-55.

O'Dorisio, M., Hauger, M. A. & Cecalupo, A. J. (1994). Somatostatin receptors in neuroblastoma: diagnostic and therapeutic implications. Semin Oncol, 21, 33-37.

Fisher, W. E., Boros, L. G., O’Dorisio, T. M., O'Dorisio, M. & Schirmer, W. J. (1994). The influence of diabetes on the growth of pancreatic cancer. (Vols. 45). pp. 151-152. Am Coll of Surgeons Surgical Forum.

Chen, F., O'Dorisio, M., Hermann, G. E., Hayes, J., Malarkey, W. B. & O’Dorisio, T. M. (1993). Mechanisms of action of long-acting analogs of somatostatin. Regul Pept, 44, 285-295.

O'Dorisio, M., Yates, A. J., VanBrocklyn, J., Saqr, H. E., Guan, Z. & Stokes, B. T. (1993). Mechanisms through which gangliosides inhibit PDGF-stimulated mitogenesis in intact Swiss 3T3 cells: Receptor tyrosine phosphorylation, intracellular calcium, and receptor binding. (Vols. 204). pp. 38-45. Exp Cell Res.

O'Dorisio, M., O’Dorisio, T. M. (1993). Neural crest tumors: rationale for somatostatin and its analogs in diagnosis and therapy. In E. L. Mazzaferri , N. A. Samaan (Eds.) Endocrine Tumors. pp. 531-542. Blackwell Scientific Publications, Inc..

O'Dorisio, M., Qualman, S. J. (1993). Neuroblastoma. In E. L. Mazzaferri , N. A. Samaan (Eds.) Endocrine Tumors. (448-456) Blackwell Scientific Publications, Inc..

Chen, F., O'Dorisio, M. (1993). Peptidergic regulation of immune function. In D. R. Brown (Eds.) Gastrointestinal Reg. Peptides, Handbook of Experimental Pharmacology. pp. 363-385. Springer-Verlag Inc..

Chen, W. W., O'Dorisio, M., Pearl, D. K. & Yates, A. J. (1992). Gangliosides inhibit platelet-derived growth factor stimulated growth of U1242mg human glioma cells. Brain Tumor Pathol, 9, 55-61.

Qualman, S. J., O'Dorisio, M., Fleshman, D., Labanowki, J., Shimada, H. & O’Dorisio, T. M. (1992). Neuroblastoma correlation of neuropeptide expression in tumor tissue with other prognostic factors. (Vols. 70). (7), pp. 2005-2012. Cancer.

O'Dorisio, M., Shannon, B. T., Mulne, A. F., Grossman, N. J., Zwick, D. & Ruymann, F. B. (1992). Vasoactive intestinal peptide receptors in lymphoblastic leukemia of childhood. Am J Ped Hem/Onc, 14(2), 144-150.

O'Dorisio, M., Fleshman, D. J., Qualman, S. J. & O’Dorisio, T. M. (1992). Vasoactive intestinal peptides: autocrine growth factor in neuroblastoma. Regul Pept, 37, 213-226.

Wenger, G. D., O'Dorisio, M. & Campolito, L. B. (1991). Assays for vasoactive intestinal peptide receptors. In P. M. Conn (Eds.) Methods in Neurosciences. pp. 362-385. Academic Press Inc..

O'Dorisio, M., Hermann, G. E. (1991). Modulation of IGA synthesis by neuroendocrine peptides. Trends Endocrinol Metabolism, 2, 68-72.

Sirinek, L. P., O'Dorisio, M. (1991). Modulation of immune function by intestinal neuropeptides. Acta Oncol, 30, 509-518.

Wimsatt, D. K., O'Dorisio, M. (1991). Modulation of mucosal IGA secretion by neuropeptides. In Z. Davidowitch (Eds.) The Biological Mechanisms of Tooth Movement and Craniofacial Adaptation. pp. 261-267. EBSCO Media.

O'Dorisio, M. (1990). Neuropeptide modulation of mucosal immune function. Peptide Therapy Index and Reviews, 2(2).

O'Dorisio, M., Wenger, G. D. (1990). Identification of neuropeptide receptors on immune effector cells. New York Academy of Sciences, 594, 104-119.

O'Dorisio, M. (1990). Neuropeptides and Immunopeptides: Messengers in a Neuroimmune Axis. A. Panerai (Eds.) (Vols. 594). pp. 1-499. New York Academy of Sciences.

O’Dorisio, M. S. (1990). Neuropeptides and immunopeptides: Preface. Annals of the New York Academy of Sciences, 594. DOI: 10.1111/j.1749-6632.1990.tb40462.x.

O’Dorisio, T. M., Mekhijan, H. S., Fassler, J. E., O'Dorisio, M., Woltering, E. A., Gaginella, T. S., Gable, T. A. & Gower, W. R. (1990). Somatostatin: Treatment of gut endocrinopathies and a mechanism of action. In Gastrointestinal Endocrinology; Receptors and Post-Receptor Mechanisms. pp. 407-421. Acad Press, Inc..

O'Dorisio, M. (1990). The role of substance P, somatostatin and vasoactive intestinal peptide in modulation of mucosal immunity. In S. Freier (Eds.) The Neuroendocrine-Immune Network. pp. 187-198. CRC Press, Inc..

Wenger, G. D., O’Dorisio, M. S. & Goetzl, E. J. (1990). Vasoactive intestinal peptide. Messenger in a neuroimmune axis. Annals of the New York Academy of Sciences, 594, 104-119. DOI: 10.1111/j.1749-6632.1990.tb40472.x.

O'Dorisio, M., Campolito, L. B. (1989). Comparison of vasoactive intestinal peptide-mediated protein phosphorylation in human lymphoblasts and colonic epithelial cells. Mol Immunol,(26), 583-590.

O'Dorisio, M., Shannon, B. T., Fleshman, D. J. & Campolito, L. B. (1989). Identification of high affinity receptors for vasoactive intestinal peptide on human lymphocytes of B cell lineage. J Immunol, 142, 3533-3536.

Tseng, J., O'Dorisio, M. (1989). Mechanism of VIP-mediated immunoregulation. In E. Goetzl , N. Spector (Eds.) Neuroimmune Networks: Physiology and Disease. pp. 105-111. Alan R. Liss, Inc..

O’Dorisio, T. M., Gaginella, T. S., O'Dorisio, M., Meleca, R. W., Wray, D. A. & Osei, K. (1989). Sandostatin: Assay and efficacy in vipoma and insulinoma. In T. M. O’Dorisio (Eds.) Sandostatin in the Treatment of GEP Endocrine Tumors. (1), pp. 43-48. Springer-Verlag.

Gaginella, T. S., O’Dorisio, T. M., Mekhjian, H. S., O'Dorisio, M. & Woltering, E. A. (1989). Tumors of gastroenteropancreatic axis. In T. M. O’Dorisio (Eds.) Sandostatin in the Treatment of GEP Endocrine Tumors. pp. 23-38. Springer-Verlag.

O’Dorisio, M. S., Vasiloff, J., Campolito, L. B., Beattie, M. S. & Bresnahan, J. C. (1988). Characterization of the vasoactive intestinal peptide receptor in rat frontal cortex. Neuroscience Research Communications, 2(1), 19-28.

O'Dorisio, M., Vasiloff, J., Beattie, M. S. & Bresnahan, J. C. (1988). Characterization of the VIP receptor in frontal cortex. Neurosci Res Commun, 2, 19-28.

O'Dorisio, M., O’Dorisio, T. M., Wood, C. L., Bresnhan, J. C., Beattie, M. S. & Campolito, L. B. (1988). Characterization of vasoactive intestinal peptide receptors in nervous and immune systems. In S. I. Said , V. Mutt (Eds.) Vasoactive Intestinal Peptide and Related Peptides. pp. 257-265. New York Academy of Sciences.

O'Dorisio, M. (1988). Neuropeptide modulation of the immune response in gut associated lymphoid tissue. Int J Neuroscience, 38, 189-198.

O’Dorisio, T. M., Gaginella, T. S., Mekhjian, H. S., Rao, B. & O'Dorisio, M. (1988). Somatostatin and analogs in the treatment of VIPOMA. In S. I. Said , V. Mutt (Eds.) Vasoactive Intestinal Peptide and Related Peptides. pp. 528-535. New York Academy of Sciences.

O’Dorisio, T. M., Gaginella, T. S., Mekhjian, H. S., Rao, B. & O’Dorisio, M. S. (1988). Somatostatin and analogues in the treatment of VIPoma. Annals of the New York Academy of Sciences, 527, 528-535.

Ercal, N., O'Dorisio, M., Vinik, A., O’Dorisio, T. M. & Kadrofske, M. (1988). Vasoactive intestinal peptide receptors in human platelet membrane: Characterization of binding and functional activity. In S. I. Said , V. Mutt (Eds.) Vasoactive Intestinal Peptide and Related Peptides. pp. 663-666. Academy of Sciences.

O'Dorisio, M. (1987). Biochemical characteristics of receptors for vasoactive intestinal polypeptide in nervous, endocrine and immune systems. Fed Proc, 46, 192-195.

McArthur, K. E., O'Dorisio, M., Wood, C. L., Zhou, Z., Gardner, J. D. & Jensen, R. T. (1987). Characterization of receptors for VIP on pancreatic acinar cell plasma membranes using covalent cross-linking. Am J Physiol, 252, G404-G412.

O’Dorisio, T. M., Mekhjian, H. S., Ellison, C. E., O'Dorisio, M., Gaginella, T. S. & Woltering, E. A. (1987). Role of peptide radioimmunoassay in understanding of peptide-peptide interactions and clinical expression of gastroenteropancreatic (GEP) endocrine tumors. Am J Med, 82, 60-67.

O'Dorisio, M., O’Dorisio, T. M. (1986). Endocrine tumors of the gastroenteropancreatic (GEP) axis. In E. L. Mazzaferri (Eds.) Endocrinology. (3), pp. 764-817. Medical Examination Pub Co.

O'Dorisio, M., Wenger, G. D. (1986). Letter to the Editor. (Vols. 135). pp. 3637. J Immunol.

Justement, L., Aldrich, W. A., Wenger, G. D., O'Dorisio, M. & Zwilling, B. (1986). Modulation of cAMP dependent protein kinase isozyme expression associated with activation of A macrophage cell line. J Immunol, 136, 270.

Justement, L. B., Aldrich, W. A., Wenger, G. D., O’Dorisio, M. S. & Zwilling, B. S. (1986). Modulation of cyclic AMP-dependent protein kinase isozyme expression associated with activation of a macrophage cell line. Journal of Immunology, 136(1), 270-277.

O'Dorisio, M. (1986). Neuropeptides and gastrointestinal immunity. Am J Med, 81, 74-82.

Maton, P. N., O’dorisio, T. M., O’dorisio, M., Malarkey, W. B., Gower, W. R., Gardner, J. D. & Jensen, R. T. (1986). Successful therapy of pancreatic cholera with the long-acting somatostatin analogue SMS 201-995: Relation between plasma concentrations of drug and clinical and biochemical responses. Scandinavian Journal of Gastroenterology, 21(S119), 181-186. DOI: 10.3109/00365528609087449.

O'Dorisio, M., Wenger, G. D., Wood, C. I. & Vassalo, L. M. (1985). cAMP dependent protein kinase in molt 4B lymphoblasts: Identification by photo affinity labeling and activation by VIP and PHI. J Immunol, 134, 4078.

Wood, C. L., O’Dorisio, M. (1985). Covalent cross-linking of vasoactive intestinal polypeptide to its receptors on intact human lymphoblasts. Journal of Biological Chemistry, 260(2), 1243-1247.

O’Dorisio, M. S., Wood, C. L., Wenger, G. D. & Vassalo, L. M. (1985). Cyclic AMP-dependent protein kinase in Molt 4b lymphoblasts: Identification by photoaffinity labeling and activation in intact cells by vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI). Journal of Immunology, 134(6), 4078-4086.

Wenger, G. D., O'Dorisio, M. (1985). Induction of cAMP dependent protein kinase I during human monocyte differentiation. J Immunol, 134, 1836-1843.

Wood, C. L., O’Dorisio, M. S., O’Dorisio, T. M. & Vassalo, L. M. (1985). Neuropeptide effects on human molt 4b lymphoblasts. Federation Proceedings, 44(4).

O’Dorisio, M. S., Wood, C. L. & O’Dorisio, T. M. (1985). Vasoactive intestinal peptide and neuropeptide modulation of the immune response. Journal of Immunology, 135(SUPPL. 2).

Wood, C. L., O’Dorisio, M., Vassalo, L. M., Malarkey, W. B. & O’Dorisio, T. M. (1985). Vasoactive intestinal peptide effects on GH3 pituitary tumor cells: high affinity binding, affinity labeling, and adenylate cyclase stimulation. Comparison with peptide histidine isoleucine and growth hormone-releasing factor. Regulatory Peptides, 12(3), 237-248. DOI: 10.1016/0167-0115(85)90065-5.

O'Dorisio, M., Wood, C. L. & O’Dorisio, T. M. (1985). Vasoactive intestinal polypeptides as a neuromodulator of lymphocyte function: A review. J Immunol, 135, 792s.

O’Dorisio, M. S., Wenger, G. D. & Wood, C. L. (1984). A possible neuro-immune axis: Demonstration of the molecular basis for vasoactive intestinal polypeptide modulation of human lymphocyte function. Federation Proceedings, 43(7).

Wenger, G. D., O’Dorisio, M. S., Vassalo, L. M. & Gadek, J. E. (1984). Biochemical parameters of the state of activation of human pulmonary alveolar macrophages obtained from smokers and nonsmokers. Federation Proceedings, 43(6).

O'Dorisio, M., Fertel, R., Finkler, E., Brooks, R. & Vassalo, L. M. (1984). Characterization of cyclic nucleotide metabolism during human monocyte differentiation. J Leukoc Biol, 35, 617-630.

Justement, L. B., Wenger, G., O’Dorisio, M. S. & Zwilling, B. S. (1984). Differential expression of cAMP dependent protein kinases in operationally defined populations of macrophages. Federation Proceedings, 43(6).

Ellison, E. C., O'Dorisio, M., Woltering, E. & O'Dorisio, T. M. (1984). Failure of secretin to stimulate gastrin release and adenylate cyclase activity in gastrinoma in vitro. Surgery, 96, 1019-1026.

Sagone, Jr., A. L., Husney, R. M., O’Dorisio, M. & Metz, E. N. (1984). Mechanisms for the oxidation of reduced gluthathione by stimulated granulocytes. Blood, 63(1), 96-104.

Beed, E. A., O’Dorisio, M. S., O’Dorisio, T. M. & Gaginella, T. S. (1983). Demonstration of a functional receptor for vasoactive intestinal polypeptide on Molt 4b T lymphoblasts. Regulatory Peptides, 6(1), 1-12. DOI: 10.1016/0167-0115(83)90129-5.

Unverferth, D. V., Fertel, R. H., Balcerzak, S. P., Magorien, R. D. & O’Dorisio, M. S. (1983). N-acetylcysteine prevents the doxorubicin-induced decrease of cyclic GMP. Seminars in Oncology, 10(1 SUPPL. 1), 49-52.

O’Dorisio, T. M., O'Dorisio, M. & Cataland, S. (1983). Overview: Endocrinology of the gastrointestinal tract. In The Compendium of Continuing Education. pp. 47. Kal Kan Symposium.

Danek, A., O’Dorisio, M. S., O’Dorisio, T. M. & George, J. M. (1983). Specific binding sites for vasoactive intestinal polypeptide on nonadherent peripheral blood lymphocytes. Journal of Immunology, 131(3), 1173-1177.

O’Dorisio, M. S., O’Dorisio, T. M., Cataland, S. & Balcerzak, S. P. (1982). Authors respond. The Journal of Laboratory and Clinical Medicine, 99(2), 297-298.

O'Dorisio, M., O’Dorisio, T. M., Cataland, S. & Balcerzak, S. P. (1982). Letter to the Editor. (Vols. 99). pp. 297. J Lab Clin Med.

O’Dorisio, M. S., Danek, A. & O’Dorisio, T. M. (1982). Specific vasoactive intestinal peptide (VIP) binding to T lymphocytes. Clinical Research, 30(2).

Fisher, J., O'Dorisio, M., O’Dorisio, T. M. & Grever, M. R. (1982). The use of vasoactive intestinal polypeptide and adenosine deaminase as biochemical markers in leukemia. In D. Yohn , J. Blakeslee (Eds.) Advances in Comparative Leukemia Research. pp. 513. Elsevier Biomedical.

Rimele, T., O'Dorisio, M. & Gaginella, T. (1981). Evidence for muscarinic receptors on rat colonic epithelial cells: Binding of [3H] quinuclidinyl benzilate. J Pharmacol Exp Ther, 218, 426-434.

O'Dorisio, M., O’Dorisio, T. M. (1981). Vasoactive intestinal peptide (VIP) in non-innervated tissues and extra-intestinal malignancies. In S. Blood (Eds.) Gut Hormones. (2), pp. 392-395. Churchill-Livingston.

O’Dorisio, M. S., Hermina, N. S., O’Dorisio, T. M. & Balcerzak, S. P. (1981). Vasoactive intestinal polypeptide modulation of lymphocyte adenylate cyclase. Journal of Immunology, 127(6), 2551-2554.

Rimele, T. J., O’Dorisio, M. S. & Gaginella, T. S. (1980). Identification of muscarinic receptors in a crude plasma membrane preparation from rat colonic epithelial cells. Pharmacologist, 22(3).

O'Dorisio, M., Sagone, A. L. (1980). Modulation of leukocyte cGMP by sulphydryl agents. In H. Sands , P. Hamet (Eds.) Advances in Cyclic Nucleotide Research. pp. 419. Academic Press.

O'Dorisio, M., O’Dorisio, T. M., Cataland, S. & Balcerza, S. P. (1980). Vasoactive intestinal polypeptide as a biochemical marker in polymorphonuclear leukocytes. J Lab Clin Med, 96, 666-672.

O'Dorisio, M., Vandenbark, G. R. & LoBuglio, A. F. (1979). Human monocyte killing of Staphylococcus Aureus: Modulation by agonists of cAMP and cGMP. Infect Immun, 26, 604-610.

Tallo, D., O’Dorisio, M. S. & Malarkey, W. B. (1979). Stimulation of intracellular cyclic AMP levels associated with divergent effect on prolactin secretion in the GH3 rodent pituitary tumor cell line. Clinical Research, 27(4).

O'Dorisio, M., Barker, K. L. (1976). Effects of estradiol on the biosynthesis of pyridine nucleotide coenzymes in the rat uterus. Biol Reprod, 15, 504-510.

O'Dorisio, M. S., Neidhart, J. A. & LoBuglio, A. F. (1976). Identification of hypoxanthine as major component of chromatographically prepared transfer factor. In M. S. Ascher , A. A. Gottlieb & C. H. Kirkpatrick (Eds.) Transfer Factor. pp. 215-224. Academic Press Inc., New York.

O’Dorisio, M. S., Neidhart, J. A., Daniel, F. B., Balcerzak, S. P. & LoBuglio, A. F. (1976). Identification of hypoxanthine as the major component of a chromatographic fraction of transfer factor. Cellular Immunology, 23(2), 191-202. DOI: 10.1016/S0022-3476(76)81083-9.

Hern, E. P., Schultz, J., O’Dorisio, M. S., Moore, R. O. & Serif, G. S. (1975). The effects of fasting, diabetes, and hypophysectomy on adipose lactic dehydrogenase isozymes. Archives of Biochemistry and Biophysics, 169(1), 331-338. DOI: 10.1016/0003-9861(75)90348-3.

O'Dorisio, M. (1972). Effects of estradiol on the synthesis of NAD and NADP in the rat uterus. University of Nebraska, College of Medicine.

O’DORISIO, M. S. (1972). Effects of Estradiol-17beta on the Synthesis of Nad and Nadp in the Rat Uterus. United States – Nebraska: The University of Nebraska - Lincoln.

O'Dorisio, M., Barker, K. L. (1970). Effects of estradiol on the levels of pyridine nucleotide coenzymes in the rat uterus. Endocrinol, 86, 1118-1126.

O'Dorisio, M. (1970). Effects of estradiol on the levels of pyridine nucleotide coenzymes in the rat uterus. University of Nebraska, College of Medicine.

O'Dorisio, M. S., Simmons, M. L. (1967). Initiation of immune response in mice subjected to hypoxia. Exp Hematol, 12, 92-97.