Mahil Rao, MD, PhD
Introduction
Dr. Rao joined the University of Iowa on November 15, 2022. He received his BA from Johns Hopkins University in 2001. He completed his Physician Scientist (MD/PhD) training at Washington University School of Medicine in 2014; (Doctor of Medicine conferred May 2014, Doctor of Philosophy conferred May 2013). Dr. Rao completed pediatric residency training at Cincinnati Children’s Hospital Medical Center and completed postdoctoral research fellow training at the same institution in 2017. He completed pediatric critical care fellowship training at Lucile Packard Children’s Hospital Stanford in 2020. He has been serving as a Clinical Scholar in the Department of Pediatrics, Division of Pediatric Critical Care Medicine at Stanford University since 2020. During this time, he was mentored in a transplant immunology lab and provided clinical service in the PICU. He is board certified in pediatrics and board certified in pediatric critical care medicine.
Dr. Rao serves the division of Critical Care as a physician scientist. He will attend on both of the PICU inpatient teams, share on-call responsibilities, participate in teaching and educational activities within the department and to help continue the development of the Critical Care program in the Stead Family Department of Pediatrics. His initial responsibilities will be primarily research focused with additional responsibilities in academic time, clinical service, and teaching. His current research interests include how critical illness influences immune function in children and how these changes in immune function can be modulated to improve patient outcomes.
Current Positions
- Associate - Pediatrics
Education
- 2022 - Postdoctoral Research Fellow, Transplant Immunology Lab, Stanford University School of Medicine, Palo Alto, California
- 2020 - Fellowship, Pediatric Critical Care Medicine, Lucile Packard Children’s Hospital Stanford, Palo Alto, California
- 2017 - Postdoctoral Research Fellow, Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
- 2017 - Pediatric Residency, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
- 2014 - MD – Medical Scientist Training Program, Washington University School of Medicine, Saint Louis, Missouri
- 2013 - PhD – Medical Scientist Training Program, Washington University School of Medicine, Saint Louis, Missouri
- 2001 - BA – Cellular and Molecular Neuroscience, John Hopkins University, Baltimore, Maryland
Research Interests
- Dr. Rao is a physician-scientist with an interest in how dysregulation in immune function affects the body’s response to severe illness. Immune dysregulation is a key component of the pathology of many different forms of severe illness, including sepsis, trauma, macrophage activation syndrome, extracorporeal membranous oxygenation, and hemophagocytic lymphohistiocytosis, and yet very few of our therapies are directed towards modulation of immune function. He is interested in understanding what pathways are dysregulated during critical illness, specifically sepsis, and how these pathways can be targeted to improve patient outcomes.
Licenses & Certifications
- American Board of Pediatrics, Pediatric Critical Care
- Advanced Cardiac Life Support
- American Board of Pediatrics, General Pediatrics
- Advanced Trauma Life Support
- Pediatric Advanced Life Support, Basic Life Support
- Medical Board of California
- Iowa Board of Medicine
Selected Publications
- Sen A,* Enriquez J,* Rao M,* Glass M, Balachandran Y, Syed S, Twist CJ, Weinberg K, Boyd SD, Bernstein D, Trickey AW, Gratzinger D, Tan B, Lapasaran MG, Robien MA, Brown M, Armstrong B, Desai D, Mazariegos G, Chin C, Fishbein TM, Venick RS, Tekin A, Zimmermann H, Trappe RU, Anagnostopoulos I, Esquivel CO, Martinez OM, Krams SM. Host microRNAs are decreased in pediatric solid-organ transplant recipients during EBV+ Post-transplant Lymphoproliferative Disorder. Front Immunol. 2022;13:994552. PMCID: PMC9595046 *equal contributors.
- Hochstetler CL, Feng Y, Sacma M, Davis AK, Rao M, Kuan CY, You LR, Geiger H, Zheng Y. KRasG12D expression in the bone marrow vascular niche affects hematopoiesis with inflammatory signals. Exp Hematol. 2019;79:3-15.e4. PMID: 31669153 *assisted lead author with generation and analysis of experimental data.
- Zhang J, Supakorndej T, Krambs JR, Rao M, Abou-Ezzi G, Ye RY, Li S, Trinkaus K, Link DC. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129(7):2920–2931. PMID: 31039135 *generated preliminary data for lead author’s study.
- Rao M, Supakorndej T, Schmidt AP, Link DC. Osteoclasts are dispensable for hematopoietic progenitor mobilization by granulocyte colony-stimulating factor in mice. Experimental hematology. 2015 Feb;43(2):110-4.e1–2.
- Christopher MJ,* Rao M,* Liu F, Woloszynek JR, Link DC. Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. The Journal of Experimental Medicine [Internet]. 2011 Feb 14;208(2):251–260. *equal contributors.
- Watkins CC, Boehning D, Kaplin AI, Rao M, Ferris CD, Snyder SH. Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission. Proceedings of the National Academy of Sciences. 2004 Feb 24;101(8):2631–2635.
- Baranano DE, Rao M, Ferris CD, Snyder SH. Biliverdin reductase: a major physiologic cytoprotectant. Proceedings of the National Academy of Sciences. 2002 Dec 10;99(25):16093–16098.