Samuel Kuperman, MD

Portrait
Ida P. Haller Chair in Child Psychiatry
Professor of Psychiatry
Professor of Pediatrics

Contact Information

Office
1873 John Pappajohn Pavilion
Iowa City, IA 52242
319-356-1482

Education

BA, Psychology, University of Iowa, Iowa City, IA
MD, University of Iowa College of Medicine, Iowa City, IA
Internship, University of Iowa Hospitals and Clinics, Iowa City, IA
Resident, General Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, IA
Resident, Child and Adolescent Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, IA

Licensure and Certifications

Iowa Controlled Substances
Child & Adolescent Psychiatry - American Board of Psychiatry and Neurology
Psychiatry certification - American Board of Psychiatry and Neurology

Publications

Dick, D., Cho, S., Latendresse, S., Aliev, F., Nurnberger, J., Edenberg, H., Schuckit, M., Hesselbrock, V., Porjesz, B., Bucholz, K., Wang, J., Goate, A., Kramer, J. & Kuperman, S. (2013). Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addict Biol. DOI: 10.1111/adb.12066.

Dick, D. M., Aliev, F., Latendresse, S., Porjesz, B., Schuckit, M., Rangaswamy, M., Hesselbrock, V., Edenberg, H., Nurnberger, J., Agrawal, A., Bierut, L., Wang, J., Bucholz, K., Kuperman, S. & Kramer, J. (2013). How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity. Twin Research and Human Genetics, 1-9.

Kuperman, S., Chan, G., Kramer, J. R., Wetherill, L., Bucholz, K. K., Dick, D., Hesselbrock, V., Porjesz, B., Rangaswamy, M. & Schuckit, M. (2013). A model to determine the likely age of an adolescent's first drink of alcohol. Pediatrics, 131(2), 242-8. PMID: 23296431.

Edwards, A. C., Aliev, F., Bierut, L. J., Bucholz, K. K., Edenberg, H., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J. I., Schuckit, M. A., Porjesz, B. & Dick, D. M. (2012). Genome-wide association study of comorbid depressive syndrome and alcohol dependence. Psychiatric Genetics, 22(1), 31-41. PMID: 22064162.

Kuperman, S., Chan, G., Kramer, J. R., Bierut, L., Bucholz, K. K., Fox, L., Hesselbrock, V., Numberger, J. I., Reich, T., Reich, W. & Schuckit, M. A. (2005). Relationship of age of first drink to child behavioral problems and family psychopathology. Alcoholism, Clinical and Experimental Research, 29(10), 1869-76. PMID: 16269917.

Kuperman, S. (2003). Tics and Tourette's syndrome in childhood. Seminars in Pediatric Neurology, 10(1), 35-40. PMID: 12785746.

Kuperman, S., Schlosser, S. S., Kramer, J. R., Bucholz, K., Hesselbrock, V., Reich, T. & Reich, W. (2001). Developmental sequence from disruptive behavior diagnosis to adolescent alcohol dependence. The American Journal of Psychiatry, 158(12), 2022-6. PMID: 11729019.

Kuperman, S., Schlosser, S. S., Kramer, J. R., Bucholz, K., Hesselbrock, V., Reich, T. & Reich, W. (2001). Risk domains associated with an adolescent alcohol dependence diagnosis. Addiction (Abingdon, England), 96(4), 629-36. PMID: 11300966.

Kuperman, S., Schlosser, S. S., Lidral, J. & Reich, W. (1999). Relationship of child psychopathology to parental alcoholism and antisocial personality disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 38(6), 686-92. PMID: 10361786.

Schuckit, M. A., Smith, T. L., Danko, G., Kramer, J., Bucholz, K. K., McCutcheon, V., Chan, G., Kuperman, S., Hesselbrock, V., Dick, D. M., Hesselbrock, M., Porjesz, B., Edenberg, H. J., Nureberger, Jr, J. I., Gregg, M., Schoen, L., Kawamura, M. & Mendoza, L. A. (2018). A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism. Alcoholism, clinical and experimental research. PMID: 29975427.

Acion, L., Kramer, J., Liu, X., Chan, G., Langbehn, D., Bucholz, K., McCutcheon, V., Hesselbrock, V., Schuckit, M., Dick, D., Hesselbrock, M. & Kuperman, S. (2018). Reliability and validity of an internalizing symptom scale based on the adolescent and adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). The American journal of drug and alcohol abuse, 1-10. PMID: 29870277.

Aliev, F., Salvatore, J. E., Agrawal, A., Almasy, L., Chan, G., Edenberg, H. J., Hesselbrock, V., Kuperman, S., Meyers, J. & Dick, D. M. (2018). A Brief Critique of the TATES Procedure. Behavior genetics, 48(2), 155-167. PMID: 29468442.

McCutcheon, V. V., Agrawal, A., Kuo, S. I., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H. J., Nurnberger, J. I., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K. (2018). Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. Addiction (Abingdon, England), 113(2), 336-345. PMID: 28804966.

Henderson, K. E., Vaidya, J. G., Kramer, J. R., Kuperman, S., Langbehn, D. R. & O'Leary, D. S. (2018). Cortical Thickness in Adolescents with a Family History of Alcohol Use Disorder. Alcoholism, clinical and experimental research, 42(1), 89-99. PMID: 29105114.

Kuperman, S., Chan, G., Kramer, J., Wetherill, L. & et al, (2017). A GABRA2 polymorphism improves a model for prediction of drinking initiation. Alcohol, 63, 1-8.

McCutcheon, V. V., Agrawal, A., Kuo, S. I., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H. J., Nurnburger, J. I., Kramer, J. R., Kuperman, S. & et al, (2017). Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. Addiction.

Schuckit, M. A., Smith, T. L., Danko, G., Anthenelli, R., Schoen, L., Kawamura, M., Kramer, J., Dick, D. M., Neale, Z., Kuperman, S. & et al, (2017). A prospective comparison of how the level of response to alcohol and impulsivity relate to future DSM-IV alcohol problems in the COGA youth panel. Alcohol Clin Exp Res.

Meyers, J. L., Zhang, J., Kramer, J., Kuperman, S., Foroud, T. & Porjesz, B. (2017). An endophenotype approach to the genetics of alcohol dependence: A genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry.

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Edenberg, H. J. & Porjesz, B. (2017). Comparison of parent, peer, psychiatric, and cannabis use influences across stages of offspring alcohol involvement: evidence from the COGA Prospective Study. Alcoholism: Clinical and Experimental Research, 41(2), 359-368.

Willsey, A. J., Fernandez, T. V., Kuperman, S. & et al, (2017). De novo coding variants are strongly associated with Tourette Disorder. Neuron, 94, 486-499.

Schuckit, M. A., Smith, T. L., Shafir, A., Kuperman, S., Kramer, J. & Bucholz, K. K. (2017). Predictors of patterns of alcohol-related blackouts over time in youth from the Collaborative Study of the Genetics of Alcoholism: The roles of genetics and cannabis. Journal of Study on Alcohol and Drugs, 78(1), 39-48.

Agrawal, A., Tillman, R., Grucza, R. A., et al,, Kramer, J. R., Kuperman, S. & et al, (2017). Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism. J Affect Disord, 213, 96-104. PMID: 28213124.

Kramer, J. R., Kuperman, S., Meyers, J. L., Numberger, J., Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J. (2016). CYP2A6 metabolism in the development of smoking behaviors in young adults. Addict Biol.

Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., Chorlian, D. B., Kang, S. J., Bauer, L., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger Jr, J. I., Tischfield, J., Wang, J. C., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B. (2016). A genome wide association study of fast beta EEG in families of European ancestry. Int J Psychophysiol.

Abdulkadir, M., Tischfield, J. A., King, R. A., Fernandez, T. V., Brown, L. W., Cheon, K. A., Coffey, B. J., de Bruijn, S. F., Elzerman, L., Garcia-Delgar, B., Gilbert, D. L., Grice, D. E., Hagstrom, J., Hedderly, T., Heyman, I., Hong, H. J., Huyser, C., Ibanez-Gomez, L., Kim, Y. K., Kim, Y. S., Koh, Y. J., Kook, A., Kuperman, S., Lamerz, A., Leventhal, B., Ludolph, A. G., Madruga-Garrido, M., Maras, A., Messchendorp, M. D., Mir, P., Morer, A., Munchau, A., Murphy, T. L., Openneer, T. J., Plessen, K. J., Rath, J. J., Roessner, V., Frundt, O., Shin, E. Y., Sival, D. A., Song, D. H., Song, J., Stolte, A. M., Tubing, J., van den Ban, E., Visscher, F., Wanderer, S., Woods, M., Zinner, S. H., State, M. W., Heiman, G. A., Hoekstra, P. J. & Dietrich, A. (2016). Pre- and perinatal complications in relation to Tourette syndrome and co-occurring obsessive-compulsive disorder and attention-deficit/hyperactivity disorder. J Psychiatr Res, 82, 126-135. PMID: 27494079.

Kapoor, M., Chou, Y. L., Edenberg, H. J., Foroud, T., Martin, N. G., Madden, P. A., Wang, J. C., Bertelsen, S., Wetherill, L., Brooks, A., Chan, G., Hesselbrock, V., Kuperman, S., Medland, S. E., Montgomery, G., Tischfield, J., Whitfield, J. B., Bierut, L. J., Heath, A. C., Bucholz, K. K., Goate, A. M. & Agrawal, A. (2016). Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures. Translational psychiatry, 6, e761. PMID: 27003187.

McCutcheon, V. V., Kramer, J. R., Edenberg, H. J., Nurnberger, J. I., Kuperman, S., Schuckit, M. A., Heath, A. C. & Bucholz, K. K. (2014). Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. Alcohol Clin Exp Res, 38(7), 2015-2023. PMID: 24942361.

Dietrich, A., Fernandez, T. V., King, R. A., State, M. W., Tischfield, J. A., Hoekstra, P. J., Heiman, G. A. & the TIC Genetics Collaborative Group (2014). The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods. European Child & Adolescent Psychiatry, 1-11. PMID: 24771252.

Agrawal, A., Lynskey, M. T., Bucholz, K. K., Kapoor, M., Almasy, L., Dick, D. M., Edenberg, H. J., Foroud, T., Goate, A., Hancock, D. B., Hartz, S., Johnson, E. O., Hesselbrock, V., Kramer, J. R., Kuperman, S., Nurnberger, Jr., J. I., Schuckit, M. & Bierut, L. J. (2014). DSM-5 cannabis use disorder: a phenotypic and genomic perspective. Drug and Alcohol Dependence, 134(1), 362-369. PMID: 24315570.

Perry, B. L., Pescosolido, B. A., Bucholz, K., Edenberg, H., Kramer, J., Kuperman, S., Schuckit, M. A. & Nurnberger, Jr., J. I. (2013). Gender-specific gene-environment interaction in alcohol dependence: the impact of daily life events and GABRA2. Behav Genet, 43(5), 402-414. PMID: 23974430.

Chorlian, D. B., Rangaswamy, M., Manz, N., Wang, J. C., Dick, D., Almasy, L., Bauer, L., Bucholz, K., Foroud, T., Hesselbrock, V., Kang, S. J., Kramer, J., Kuperman, S., Nurnberger, Jr, J., Rice, J., Schuckit, M., Tischfield, J., Edenberg, H. J., Goate, A., Bierut, L. & Porjesz, B. (2013). Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. Behav Genet, 43(5), 386-401. PMID: 23963516.

Kos, M. Z., Yan, J., Dick, D. M., Agrawal, A., Bucholz, K. K., Rice, J. P., Johnson, E. O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A. M., Tischfield, J. A., Foroud, T., Nurnberger, J., Hesselbrock, V., Porjesz, B., Bierut, L. J., Edenberg, H. J. & Almasy, L. (2013). Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. Genes, Brain, and Behavior.

Agrawal, A., Wetherill, L., Bucholz, K. K., Kramer, J., Kuperman, S., Lynskey, M. T., Nurnberger, J. I., Schuckit, M., Tischfield, J. A., Edenberg, H. J., Foroud, T. & Bierut, L. J. (2013). Genetic influences on craving for alcohol. Addictive Behaviors, 38(2), 1501-8. PMID: 22481050.

Yan, J., Aliev, F., Webb, B. T., Kendler, K. S., Williamson, V. S., Edenberg, H. J., Agrawal, A., Kos, M. Z., Almasy, L., Nurnberger, J. I., Schuckit, M. A., Kramer, J. R., Rice, J. P., Kuperman, S., Goate, A. M., Tischfield, J. A., Porjesz, B. & Dick, D. M. (2013). Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. Addiction Biology.

Rice, J. P., Hartz, S. M., Agrawal, A., Almasy, L., Bennett, S., Breslau, N., Bucholz, K. K., Doheny, K. F., Edenberg, H. J., Goate, A. M., Hesselbrock, V., Howells, W. B., Johnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Laurie, C., Manolio, T. A., Neuman, R. J., Nurnberger, J. I., Porjesz, B., Pugh, E., Ramos, E. M., Saccone, N., Saccone, S., Schuckit, M. & Bierut, L. J. (2012). CHRNB3 is more strongly associated with Fagerstrom test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Addiction, 107(11), 2019-28. PMID: 22524403.

Schuckit, M. A., Smith, T. L., Trim, R. S., Kuperman, S., Kramer, J., Hesselbrock, V., Bucholz, K. K., Nurnberger, J. I., Hesselbrock, M. & Saunders, G. (2012). Sex differences in how a low sensitivity to alcohol relates to later heavy drinking. Drug and Alcohol Review, 31(7), 871-80. PMID: 22708705.

Wang, J. C., Foroud, T., Hinrichs, A. L., Le, N. X., Bertelsen, S., Budde, J. P., Harari, O., Koller, D. L., Wetherill, L., Agrawal, A., Almasy, L., Brooks, A. I., Bucholz, K., Dick, D., Hesselbrock, V., Johnson, E. O., Kang, S., Kapoor, M., Kramer, J., Kuperman, S., Madden, P. A., Manz, N., Martin, N. G., McClintick, J. N., Montgomery, G. W., Nurnberger, J. I., Rangaswamy, M., Rice, J., Schuckit, M., Tischfield, J. A., Whitfield, J. B., Xuei, X., Porjesz, B., Heath, A. C., Edenberg, H. J., Bierut, L. J. & Goate, A. M. (2012). A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Molecular Psychiatry.

Lin, P., Hartz, S. M., Wang, J. C., Agrawal, A., Zhang, T. X., McKenna, N., Bucholz, K., Brooks, A. I., Tischfield, J. A., Edenberg, H. J., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Schuckit, M. A., Goate, A. M., Bierut, L. J. & Rice, J. P. (2012). Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcoholism, Clinical and Experimental Research, 36(9), 1512-8. PMID: 22702843.

Kang, S. J., Rangaswamy, M., Manz, N., Wang, J. C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D. B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L. J., Edenberg, H. J., Goate, A., Foroud, T. & Porjesz, B. (2012). Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6. Genes, Brain, and Behavior, 11(6), 712-9. PMID: 22554406.

Bierut, L. J., Goate, A. M., Breslau, N., Johnson, E. O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K. K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N. L., Schuckit, M., Tischfield, J., Wang, J. C., Foroud, T., Rice, J. P. & Edenberg, H. J. (2012). ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. Molecular Psychiatry, 17(4), 445-50. PMID: 21968928.

Kapoor, M., Wang, J. C., Bertelsen, S., Bucholz, K., Budde, J. P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, S., Manz, N., Nurnberger, J., Porjesz, B., Rice, J., Tischfield, J., Xuei, X., Schuckit, M., Edenberg, H. J., Bierut, L. J. & Goate, A. M. (2012). Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. PLOS ONE, 7(3), e33513. PMID: 22438940.

Kuperman, S., Calarge, C., Kolar, A., Holman, T., Barnett, M. & Perry, P. (2011). An open-label trial of aripiprazole in the treatment of aggression in male adolescents diagnosed with conduct disorder. Annals of Clinical Psychiatry, 23(4), 270-6. PMID: 22073384.

Dick, D. M., Aliev, F., Krueger, R. F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V., Nurnberger, J., Almasy, L., Porjesz, B., Edenberg, H. J., Bucholz, K., Kramer, J., Kuperman, S. & Bierut, L. (2011). Genome-wide association study of conduct disorder symptomatology. Molecular Psychiatry, 16(8), 800-8. PMID: 20585324.

Agrawal, A., Lynskey, M. T., Hinrichs, A., Grucza, R., Saccone, S. F., Krueger, R., Neuman, R., Howells, W., Fisher, S., Fox, L., Cloninger, R., Dick, D. M., Doheny, K. F., Edenberg, H. J., Goate, A. M., Hesselbrock, V., Johnson, E., Kramer, J., Kuperman, S., Nurnberger, J. I., Pugh, E., Schuckit, M. & Tischfield, J. (2011). A genome-wide association study of DSM-IV cannabis dependence. Addiction Biology, 16(3), 514-8. PMID: 21668797.

Kim, H. Y., Eyheramonho, M. B., Pichavant, M., Gonzalez Cambaceres, C., Matangkasombut, P., Cervio, G., Kuperman, S., Moreiro, R., Konduru, K., Manangeeswaran, M., Freeman, G. J., Kaplan, G. G., DeKruyff, R. H., Umetsu, D. T. & Rosenzweig, S. D. (2011). A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans. The Journal of Clinical Investigation, 121(3), 1111-8. PMID: 21339644.

Kramer, J., Chan, G., Flury-Wetherill, L., Kuperman, S., Edenberg, H., Bucholz, K., Xuei, X., Dick, D. & Nurnberger Jr, J. (2011). The Serotonin Transporter Gene SLC6A4, Environmental Adversity, and Heavy Alcohol Consumption. Behavior Genetics.

Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X., Flury-Wetherill, L., Koller, D., Bierut, L. J., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M. A., Foroud, T., Edenberg, H. J., Porjesz, B. & Almasy, L. (2011). Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 156B(1), 44-58. PMID: 21184583.

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. & Hesselbrock, V. (2010). Obesity, smoking, and frontal brain dysfunction. The American Journal on Addictions, 19(5), 391-400. PMID: 20716301.

Dick, D. M., Meyers, J., Aliev, F., Nurnberger, J., Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H. J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V. & Bierut, L. (2010). Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 153B(6), 1179-88. PMID: 20468071.

Derringer, J., Krueger, R. F., Dick, D. M., Saccone, S., Grucza, R. A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H. J., Foroud, T., Nurnberger, J. I., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Porjesz, B., Schuckit, M. A. & Bierut, L. J. (2010). Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychological Science, 21(9), 1282-90. PMID: 20732903.

Cavazos-Rehg, P. A., Spitznagel, E. L., Bucholz, K. K., Nurnberger, J., Edenberg, H. J., Kramer, J. R., Kuperman, S., Hesselbrock, V. & Bierut, L. J. (2010). Predictors of sexual debut at age 16 or younger. Archives of Sexual Behavior, 39(3), 664-73. PMID: 18846417.

Chen, A. C., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger, J., O'Connor, S. J., Edenberg, H. J., Schuckit, M. A., Tischfield, J., Foroud, T., Bierut, L. J., Rohrbaugh, J., Rice, J. P., Goate, A., Hesselbrock, V. & Porjesz, B. (2010). Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. Alcoholism, Clinical and Experimental Research, 34(6), 988-96. PMID: 20374216.

Edenberg, H. J., Koller, D. L., Xuei, X., Wetherill, L., McClintick, J. N., Almasy, L., Bierut, L. J., Bucholz, K. K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J. I., Rice, J. P., Schuckit, M. A., Taylor, R., Todd Webb, B., Tischfield, J. A., Porjesz, B. & Foroud, T. (2010). Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcoholism, Clinical and Experimental Research, 34(5), 840-52. PMID: 20201924.

Calarge, C. A., Zimmerman, B., Xie, D., Kuperman, S. & Schlechte, J. A. (2010). A cross-sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys. The Journal of Clinical Psychiatry, 71(3), 338-47. PMID: 20331935.

Bierut, L. J., Agrawal, A., Bucholz, K. K., Doheny, K. F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A. L., Almasy, L., Breslau, N., Culverhouse, R. C., Dick, D. M., Edenberg, H. J., Foroud, T., Grucza, R. A., Hatsukami, D., Hesselbrock, V., Johnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R. J., Nöthen, M. M., Nurnberger, J. I., Porjesz, B., Ridinger, M., Saccone, N. L., Saccone, S. F., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Rietschel, M., Goate, A. M. & Rice, J. P. (2010). A genome-wide association study of alcohol dependence. Proceedings of the National Academy of Sciences of the United States of America, 107(11), 5082-7. PMID: 20202923.

Xuei, X., Flury-Wetherill, L., Dick, D., Goate, A., Tischfield, J., Nurnberger, J., Schuckit, M., Kramer, J., Kuperman, S., Hesselbrock, V., Porjesz, B., Foroud, T. & Edenberg, H. J. (2010). GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 153B(2), 418-27. PMID: 19536785.

Kramer, J. R., Chan, G., Hesselbrock, V. M., Kuperman, S., Bucholz, K. K., Edenberg, H. J., Schuckit, M. A., Nurnberger, J. I., Foroud, T., Dick, D. M., Bierut, L. J. & Porjesz, B. (2010). A principal components analysis of the abbreviated Desires for Alcohol Questionnaire (DAQ). Journal of Studies on Alcohol and Drugs, 71(1), 150-5. PMID: 20105425.

Roopesh, B. N., Rangaswamy, M., Kamarajan, C., Chorlian, D. B., Stimus, A., Bauer, L. O., Rohrbaugh, J., O'Connor, S. J., Kuperman, S., Schuckit, M. & Porjesz, B. (2009). Priming deficiency in male subjects at risk for alcoholism: the N4 during a lexical decision task. Alcoholism, Clinical and Experimental Research, 33(12), 2027-36. PMID: 19764939.

Remesar, M. C., Gamba, C., Colaianni, I. F., Puppo, M., Sartor, P. A., Murphy, E. L., Neilands, T. B., Ridolfi, M. A., Leguizamón, M. S., Kuperman, S. & Del Pozo, A. E. (2009). Estimation of sensitivity and specificity of several Trypanosoma cruzi antibody assays in blood donors in Argentina. Transfusion, 49(11), 2352-8. PMID: 19903291.

Kramer, J. R., Chan, G., Kuperman, S., Bucholz, K. K., Edenberg, H. J., Schuckit, M. A., Polgreen, L. A., Kapp, E. S., Hesselbrock, V. M., Nurnberger, J. I. & Bierut, L. J. (2009). A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA). Journal of Studies on Alcohol and Drugs, 70(4), 623-7. PMID: 19515304.

Wang, J. C., Grucza, R., Cruchaga, C., Hinrichs, A. L., Bertelsen, S., Budde, J. P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B., Edenberg, H. J., Bierut, L. J. & Goate, A. M. (2009). Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Molecular Psychiatry, 14(5), 501-10. PMID: 18414406.

Chen, A. C., Tang, Y., Rangaswamy, M., Wang, J. C., Almasy, L., Foroud, T., Edenberg, H. J., Hesselbrock, V., Nurnberger, J., Kuperman, S., O'Connor, S. J., Schuckit, M. A., Bauer, L. O., Tischfield, J., Rice, J. P., Bierut, L., Goate, A. & Porjesz, B. (2009). Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 150B(3), 359-68. PMID: 18618593.

Calarge, C. A., Acion, L., Kuperman, S., Tansey, M. & Schlechte, J. A. (2009). Weight gain and metabolic abnormalities during extended risperidone treatment in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 19(2), 101-9. PMID: 19364288.

Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., Bucholz, K. K., Cloninger, C. R., Neuman, R. J., Budde, J. P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J. I., Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M. A., Edenberg, H. J., Rice, J. P., Goate, A. M. & Bierut, L. J. (2008). A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biological Psychiatry, 64(11), 922-9. PMID: 18519132.

Kramer, J. R., Chan, G., Dick, D. M., Kuperman, S., Bucholz, K. K., Edenberg, H. J., Polgreen, L. A., Hesselbrock, V. M., Schuckit, M. A., Nurnberger, J. I., Kapp, E. S., Porjesz, B. & Bierut, L. J. (2008). Multiple-domain predictors of problematic alcohol use in young adulthood. Journal of Studies on Alcohol and Drugs, 69(5), 649-59. PMID: 18781239.

Bierut, L. J., Stitzel, J. A., Wang, J. C., Hinrichs, A. L., Grucza, R. A., Xuei, X., Saccone, N. L., Saccone, S. F., Bertelsen, S., Fox, L., Horton, W. J., Breslau, N., Budde, J., Cloninger, C. R., Dick, D. M., Foroud, T., Hatsukami, D., Hesselbrock, V., Johnson, E. O., Kramer, J., Kuperman, S., Madden, P. A., Mayo, K., Nurnberger, J., Pomerleau, O., Porjesz, B., Reyes, O., Schuckit, M., Swan, G., Tischfield, J. A., Edenberg, H. J., Rice, J. P. & Goate, A. M. (2008). Variants in nicotinic receptors and risk for nicotine dependence. The American Journal of Psychiatry, 165(9), 1163-71. PMID: 18519524.

Edenberg, H. J., Wang, J., Tian, H., Pochareddy, S., Xuei, X., Wetherill, L., Goate, A., Hinrichs, T., Kuperman, S., Nurnberger, J. I., Schuckit, M., Tischfield, J. A. & Foroud, T. (2008). A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. Human Molecular Genetics, 17(12), 1783-9. PMID: 18319328.

Dick, D. M., Aliev, F., Wang, J. C., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J., Xuei, X., Conneally, P. M., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J. A., Hesselbrock, V., Edenberg, H. J., Porjesz, B., Rice, J. P., Bierut, L. & Goate, A. (2008). A systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. Biological Psychiatry, 63(11), 1047-53.

Edenberg, H. J., Xuei, X., Wetherill, L. F., Bierut, L., Bucholz, K., Dick, D. M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Almasy, L. A., Nurnberger, J. I. & Foroud, T. (2008). Association of NFKB1, which encodes a subunit of the transcription factor NF-kappaB, with alcohol dependence. Human Molecular Genetics, 17(7), 963-70. PMID: 18079108.

Dick, D. M., Aliev, F., Wang, J. C., Grucza, R. A., Schuckit, M., Kuperman, S., Kramer, J., Hinrichs, A., Bertelsen, S., Budde, J. P., Hesselbrock, V., Porjesz, B., Edenberg, H. J., Bierut, L. J. & Goate, A. (2008). Using dimensional models of externalizing psychopathology to aid in gene identification. Archives of General Psychiatry, 65(3), 310-8. PMID: 18316677.

Agrawal, A., Hinrichs, A. L., Dunn, G., Bertelsen, S., Dick, D. M., Saccone, S. F., Saccone, N. L., Grucza, R. A., Wang, J. C., Cloninger, C. R., Edenberg, H. J., Foroud, T., Hesselbrock, V., Kramer, J., Bucholz, K. K., Kuperman, S., Nurnberger, J. I., Porjesz, B., Schuckit, M. A., Goate, A. M. & Bierut, L. J. (2008). Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Drug and Alcohol Dependence, 93(1-2), 12-20. PMID: 17942244.

Cavazos-Rehg, P. A., Spitznagel, E. L., Bucholz, K. K., Norberg, K., Reich, W., Nurnberger, J., Hesselbrock, V., Kramer, J., Kuperman, S. & Bierut, L. J. (2007). The relationship between alcohol problems and dependence, conduct problems and diagnosis, and number of sex partners in a sample of young adults. Alcoholism, Clinical and Experimental Research, 31(12), 2046-52. PMID: 18034697.

Schuckit, M. A., Smith, T. L., Danko, G. P., Pierson, J., Trim, R., Nurnberger, J. I., Kramer, J., Kuperman, S., Bierut, L. J. & Hesselbrock, V. (2007). A comparison of factors associated with substance-induced versus independent depressions. Journal of Studies on Alcohol and Drugs, 68(6), 805-12. PMID: 17960298.

Dick, D. M., Wang, J. C., Plunkett, J., Aliev, F., Hinrichs, A., Bertelsen, S., Budde, J. P., Goldstein, E. L., Kaplan, D., Edenberg, H. J., Nurnberger, J., Hesselbrock, V., Schuckit, M., Kuperman, S., Tischfield, J., Porjesz, B., Begleiter, H., Bierut, L. J. & Goate, A. (2007). Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. Alcoholism, Clinical and Experimental Research, 31(10), 1645-53. PMID: 17850642.

Tang, Y., Chorlian, D. B., Rangaswamy, M., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Rohrbaugh, J., Schuckit, M., Stimus, A. & Begleiter, H. (2007). Genetic influences on bipolar EEG power spectra. International Journal of Psychophysiology, 65(1), 2-9. PMID: 17383039.

Schuckit, M. A., Smith, T. L., Danko, G. P., Pierson, J., Hesselbrock, V., Bucholz, K. K., Kramer, J., Kuperman, S., Dietiker, C., Brandon, R. & Chan, G. (2007). The ability of the Self-Rating of the Effects of Alcohol (SRE) Scale to predict alcohol-related outcomes five years later. Journal of Studies on Alcohol and Drugs, 68(3), 371-378. PMID: 17446976.

Dick, D. M., Aliev, F., Kramer, J., Wang, J. C., Hinrichs, A., Bertelsen, S., Kuperman, S., Schuckit, M., Nurnberger, J., Edenberg, H. J., Porjesz, B., Begleiter, H., Hesselbrock, V., Goate, A. & Bierut, L. (2007). Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence. Behavior Genetics, 37(2), 265-72. PMID: 17160701.

Dick, D. M., Plunkett, J., Hamlin, D., Nurnberger, J., Kuperman, S., Schuckit, M., Hesselbrock, V., Edenberg, H. & Bierut, L. (2007). Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Psychiatric Genetics, 17(1), 35-8. PMID: 17167343.

Wang, J. C., Hinrichs, A. L., Bertelsen, S., Stock, H., Budde, J. P., Dick, D. M., Bucholz, K. K., Rice, J., Saccone, N., Edenberg, H. J., Hesselbrock, V., Kuperman, S., Schuckit, M. A., Bierut, L. J. & Goate, A. M. (2007). Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. Alcoholism, Clinical and Experimental Research, 31(2), 209-15. PMID: 17250611.

Rangaswamy, M., Jones, K. A., Porjesz, B., Chorlian, D. B., Padmanabhapillai, A., Kamarajan, C., Kuperman, S., Rohrbaugh, J., O'Connor, S. J., Bauer, L. O., Schuckit, M. A. & Begleiter, H. (2007). Delta and theta oscillations as risk markers in adolescent offspring of alcoholics. International Journal of Psychophysiology, 63(1), 3-15. PMID: 17129626.

Numberger Jr., J., Kuperman, S., Flury-Wetherill, L. & Meyer, E. (2007). Genetics of comorbid mood disorder and alcohol dependence. Journal of Dual Diagnosis: Research and Practice in Substance Abuse Comorbidity, 3-2, 31-46.

Xuei, X., Dick, D., Flury-Wetherill, L., Tian, H. J., Agrawal, A., Bierut, L., Goate, A., Bucholz, K., Schuckit, M., Nurnberger, J., Tischfield, J., Kuperman, S., Porjesz, B., Begleiter, H., Foroud, T. & Edenberg, H. J. (2006). Association of the kappa-opioid system with alcohol dependence. Molecular Psychiatry, 11(11), 1016-24. PMID: 16924269.

Padmanabhapillai, A., Tang, Y., Ranganathan, M., Rangaswamy, M., Jones, K. A., Chorlian, D. B., Kamarajan, C., Stimus, A., Kuperman, S., Rohrbaugh, J., O'Connor, S. J., Bauer, L. O., Schuckit, M. A., Begleiter, H. & Porjesz, B. (2006). Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task. International Journal of Psychophysiology, 62(2), 262-71. PMID: 16887227.

Fisher, S. L., Bucholz, K. K., Reich, W., Fox, L., Kuperman, S., Kramer, J., Hesselbrock, V., Dick, D. M., Nurnberger, J. I., Edenberg, H. J. & Bierut, L. J. (2006). Teenagers are right--parents do not know much: an analysis of adolescent-parent agreement on reports of adolescent substance use, abuse, and dependence. Alcoholism, Clinical and Experimental Research, 30(10), 1699-710. PMID: 17010137.

Jones, K. A., Porjesz, B., Almasy, L., Bierut, L., Dick, D., Goate, A., Hinrichs, A., Rice, J. P., Wang, J. C., Bauer, L. O., Crowe, R., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger, J., O'Connor, S. J., Rohrbaugh, J., Schuckit, M. A., Tischfield, J., Edenberg, H. J. & Begleiter, H. (2006). A cholinergic receptor gene (CHRM2) affects event-related oscillations. Behavior Genetics, 36(5), 627-39. PMID: 16823639.

Agrawal, A., Edenberg, H. J., Foroud, T., Bierut, L. J., Dunne, G., Hinrichs, A. L., Nurnberger, J. I., Crowe, R., Kuperman, S., Schuckit, M. A., Begleiter, H., Porjesz, B. & Dick, D. M. (2006). Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behavior Genetics, 36(5), 640-50. PMID: 16622805.

Duncan, A. E., Neuman, R. J., Kramer, J. R., Kuperman, S., Hesselbrock, V. M. & Bucholz, K. K. (2006). Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women. Drug and Alcohol Dependence, 84(1), 122-32. PMID: 16455211.

Dick, D. M., Bierut, L., Hinrichs, A., Fox, L., Bucholz, K. K., Kramer, J., Kuperman, S., Hesselbrock, V., Schuckit, M., Almasy, L., Tischfield, J., Porjesz, B., Begleiter, H., Nurnberger, J., Xuei, X., Edenberg, H. J. & Foroud, T. (2006). The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behavior Genetics, 36(4), 577-90. PMID: 16557364.

Edenberg, H. J., Xuei, X., Chen, H. J., Tian, H., Wetherill, L. F., Dick, D. M., Almasy, L., Bierut, L., Bucholz, K. K., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M., Tischfield, J., Begleiter, H. & Foroud, T. (2006). Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Human Molecular Genetics, 15(9), 1539-49. PMID: 16571603.

Gogineni, A., King, S., Jackson, K., Kramer, J., Bucholz, K., Chan, G., Iacono, W., Kuperman, S., Larkins, J. M., Longabaugh, R., McGue, M., Polgreen, L., Sher, K. J., Stout, R., Strong, D. & Woolard, R. (2006). Female offspring of alcoholic individuals: recent findings on alcoholism and psychopathology risks: symposium presented at the Research Society on Alcoholism, 2004, Vancouver Aruna Gogineni, Chair. Alcoholism, Clinical and Experimental Research, 30(2), 377-87. PMID: 16441287.

Hinrichs, A. L., Wang, J. C., Bufe, B., Kwon, J. M., Budde, J., Allen, R., Bertelsen, S., Evans, W., Dick, D., Rice, J., Foroud, T., Nurnberger, J., Tischfield, J. A., Kuperman, S., Crowe, R., Hesselbrock, V., Schuckit, M., Almasy, L., Porjesz, B., Edenberg, H. J., Begleiter, H., Meyerhof, W., Bierut, L. J. & Goate, A. M. (2006). Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. American Journal of Human Genetics, 78(1), 103-11.

Ohannessian, C. M., Hesselbrock, V. M., Ruddy, K., Dick, D., Kramer, J., Kuperman, S., Bucholz, K. & Schuckit, M. (2006). The effects of parental substance use on adolescent psychological adjustment: A micro-level approach. Prevention Researcher, 13(4), 7-9.

Dick, D. M., Aliev, F., Bierut, L., Goate, A., Rice, J., Hinrichs, A., Bertelsen, S., Wang, J. C., Dunn, G., Kuperman, S., Schuckit, M., Nurnberger, J., Porjesz, B., Beglieter, H., Kramer, J. & Hesselbrock, V. (2006). Linkage analyses of IQ in the collaborative study on the genetics of alcoholism (COGA) sample. Behavior Genetics, 36(1), 77-86. PMID: 16341907.

Conner, K. R., Hesselbrock, V. M., Schuckit, M. A., Hirsch, J. K., Knox, K. L., Meldrum, S., Bucholz, K. K., Kramer, J., Kuperman, S., Preuss, U. & Soyka, M. (2006). Precontemplated and impulsive suicide attempts among individuals with alcohol dependence. Journal of Studies on Alcohol, 67(1), 95-101. PMID: 16536133.

Remesar, M., Gamba, C., Kuperman, S., Marcosa, M. A., Miguez, G., Caldarola, S., Perez-Bianco, R., Manterola, A. & Del Pozo, A. (2005). Antibodies to hepatitis C and other viral markersin multi-transfused patients from Argentina. Journal of Clinical Virology, 34 Suppl 2, S20-6. PMID: 16461236.

Calarge, C., Kuperman, S. (2005). Fluoxetine for depression relapse prevention. Journal of the American Academy of Child and Adolescent Psychiatry, 44(10), 966-7; author reply 967-8. PMID: 16175095.

Ohannessian, C. M., Hesselbrock, V. M., kRAMER, j., Kuperman, s., Bucholz, K. K., Schuckit, M. A. & Nurnberger, J. I. (2005). The Relationship Between Parental Psychopathology and Adolescent Psychopathology: An Examination of Gender Patterns. Journal of Emotional and Behavioral Disorders, 13(2), 67-76. DOI: 10.1177/10634266050130020101.

Schuckit, M. A., Smith, T. L., Danko, G. P., Anderson, K. G., Brown, S. A., Kuperman, S., Kramer, J., Hesselbrock, V. & Bucholz, K. (2005). Evaluation of a level of response to alcohol-based structural equation model in adolescents. Journal of Studies on Alcohol, 66(2), 174-84. PMID: 15957668.

Duncan, A. E., Neuman, R. J., Kramer, J., Kuperman, S., Hesselbrock, V., Reich, T. & Bucholz, K. K. (2005). Are there subgroups of bulimia nervosa based on comorbid psychiatric disorders. The International Journal of Eating Disorders, 37(1), 19-25. PMID: 15690461.

Streyffeler, L., Altmaier, E. M., Kuperman, S. & Patrick, L. E. (2005). Development of a medical school admission interview pase 2: Predictive validity of cognitive and non-cognitive attributes. Medical Education Online, 10, 14.

Schuckit, M. A., Smith, T. L., Danko, G., Kuperman, S., Bierut, L. J. & Hesselbrock, V. (2005). Correlations among first-degree relatives for responses on the Self-Rating of the Effects of Alcohol Questionnaire in teenagers. Journal of Studies on Alcohol, 66(1), 62-5. PMID: 15830904.

Nurnberger, J. I., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E. T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A. L., Kuperman, S., Hesselbrock, V. & Porjesz, B. (2004). A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands. Archives of General Psychiatry, 61(12), 1246-56. PMID: 15583116.

Ohannessian, C. M., Hesselbrock, V. M., Kramer, J., Bucholz, K. K., Schuckit, M. A., Kuperman, S. & Nurnberger, J. I. (2004). Parental substance use consequences and adolescent psychopathology. Journal of Studies on Alcohol, 65(6), 725-30. PMID: 15700509.

Ohannessian, C. M., Hesselbrock, V. M., Kramer, J., Kuperman, S., Bucholz, K. K., Schuckit, M. A. & Nurnberger, J. I. (2004). The relationship between parental alcoholism and adolescent psychopathology: a systematic examination of parental comorbid psychopathology. Journal of Abnormal Child Psychology, 32(5), 519-33. PMID: 15500031.

Jones, K. A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Wang, J. C., Dick, D. M., Hinrichs, A., Kwon, J., Rice, J. P., Rohrbaugh, J., Stock, H., Wu, W., Bauer, L. O., Chorlian, D. B., Crowe, R. R., Edenberg, H. J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S. J., Schuckit, M. A., Stimus, A. T., Tischfield, J. A., Reich, T. & Begleiter, H. (2004). Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. International Journal of Psychophysiology, 53(2), 75-90. PMID: 15210286.

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Wang, K., Jones, K. A., Kuperman, S., Rohrbaugh, J., O'Connor, S. J., Bauer, L. O., Reich, T. & Begleiter, H. (2004). Resting EEG in offspring of male alcoholics: beta frequencies. International Journal of Psychophysiology, 51(3), 239-51. PMID: 14962576.

Dick, D. M., Li, T. K., Edenberg, H. J., Hesselbrock, V., Kramer, J., Kuperman, S., Porjesz, B., Bucholz, K., Goate, A., Nurnberger, J. & Foroud, T. (2004). A genome-wide screen for genes influencing conduct disorder. Molecular Psychiatry, 9(1), 81-6. PMID: 14699444.

Dick, D. M., Edenberg, H. J., Xuei, X., Goate, A., Kuperman, S., Schuckit, M., Crowe, R., Smith, T. L., Porjesz, B., Begleiter, H. & Foroud, T. (2004). Association of GABRG3 with alcohol dependence. Alcoholism, Clinical and Experimental Research, 28(1), 4-9. PMID: 14745296.

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Choi, K., Jones, K. A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T. & Begleiter, H. (2003). Theta power in the EEG of alcoholics. Alcoholism, Clinical and Experimental Research, 27(4), 607-15. PMID: 12711923.

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D. B., Stimus, A. T., Kuperman, S., O'Connor, S. J., Rohrbaugh, J., Bauer, L. O., Edenberg, H. J., Goate, A., Rice, J. P. & Reich, T. (2002). Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biological Psychology, 61(1-2), 229-48. PMID: 12385677.

Kuperman, S. (2002). Tic disorders in the adolescent. Adolescent Medicine (Philadelphia, Pa.), 13(3), 537-51. PMID: 12270799.

Rangaswamy, M., Porjesz, B., Chorlian, D. B., Wang, K., Jones, K. A., Bauer, L. O., Rohrbaugh, J., O'Connor, S. J., Kuperman, S., Reich, T. & Begleiter, H. (2002). Beta power in the EEG of alcoholics. Biological Psychiatry, 52(8), 831-42. PMID: 12372655.

Porjesz, B., Almasy, L., Edenberg, H. J., Wang, K., Chorlian, D. B., Foroud, T., Goate, A., Rice, J. P., O'Connor, S. J., Rohrbaugh, J., Kuperman, S., Bauer, L. O., Crowe, R. R., Schuckit, M. A., Hesselbrock, V., Conneally, P. M., Tischfield, J. A., Li, T. K., Reich, T. & Begleiter, H. (2002). Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proceedings of the National Academy of Sciences of the United States of America, 99(6), 3729-33. PMID: 11891318.

Gaffney, G. R., Perry, P. J., Lund, B. C., Bever-Stille, K. A., Arndt, S. & Kuperman, S. (2002). Risperidone versus clonidine in the treatment of children and adolescents with Tourette's syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 41(3), 330-6. PMID: 11886028.

Wolf, R., Wolf, D. & Kuperman, S. (2001). Focal nodular hyperplasia of the liver after intraconazole treatment. Journal of Clinical Gastroenterology, 33(5), 418-20. PMID: 11606862.

Kuperman, S., Perry, P. J., Gaffney, G. R., Lund, B. C., Bever-Stille, K. A., Arndt, S., Holman, T. L., Moser, D. J. & Paulsen, J. S. (2001). Bupropion SR vs. methylphenidate vs. placebo for attention deficit hyperactivity disorder in adults. Annals of Clinical Psychiatry, 13(3), 129-34. PMID: 11791949.

Patrick, L. E., Altmaier, E. M., Kuperman, S. & Ugolini, K. (2001). A structured interview for medical school admission, Phase 1: initial procedures and results. Academic Medicine, 76(1), 66-71. PMID: 11154199.

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H. J., Chorlian, D. B., Kuperman, S., O'Connor, S. J., Rohrbaugh, J., Bauer, L. O., Foroud, T., Rice, J. P., Reich, T. & Begleiter, H. (2001). Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. American Journal of Human Genetics, 68(1), 128-135. PMID: 11102287.

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J. & Begleiter, H. (2000). Frontal P300 decrements, alcohol dependence, and antisocial personality disorder. Biological Psychiatry, 47(12), 1064-71. PMID: 10862806.

Anokhin, A. P., Vedeniapin, A. B., Sirevaag, E. J., Bauer, L. O., O'Connor, S. J., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J. & Rohrbaugh, J. W. (2000). The P300 brain potential is reduced in smokers. Psychopharmacology, 149(4), 409-13. PMID: 10867969.

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D. B., O'Connor, S. J., Kuperman, S., Rohrbaugh, J., Bauer, L. O., Reich, T., Polich, J. & Begleiter, H. (1999). Heritability of event-related brain potentials in families with a history of alcoholism. American Journal of Medical Genetics, 88(4), 383-90. PMID: 10402506.

Neuman, R. J., Todd, R. D., Heath, A. C., Reich, W., Hudziak, J. J., Bucholz, K. K., Madden, P. A., Begleiter, H., Porjesz, B., Kuperman, S., Hesselbrock, V. & Reich, T. (1999). Evaluation of ADHD typology in three contrasting samples: a latent class approach. Journal of the American Academy of Child and Adolescent Psychiatry, 38(1), 25-33. PMID: 9893413.

Begleiter, H., Reich, T., Nurnberger, J., Li, T. K., Conneally, P. M., Edenberg, H., Crowe, R., Kuperman, S., Schuckit, M., Bloom, F., Hesselbrock, V., Porjesz, B., Cloninger, C. R., Rice, J. & Goate, A. (1999). Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genetic Epidemiology, 17 Suppl 1, S25-30. PMID: 10597407.

David, B. (Eds.) (1999). Your Child—What Every Parent Needs to Know: What’s Normal, What’s Not, and When to Seek Help. (Vols. 60). pp. 489. Pruitt, New York, Harper Collins Publisher: Journal of Clinical Psychiatry.

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H. J., Foroud, T., Goate, A., Litke, A., Chorlian, D. B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L. O., Kuperman, S., O'Connor, S. J. & Rohrbaugh, J. (1998). Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism. Alcoholism, Clinical and Experimental research, 22(6), 1317-23. PMID: 9756048.

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H. J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L. O., O'Connor, S. J., Chorlian, D. B., Li, T. K., Conneally, P. M., Hesselbrock, V., Rice, J. P., Schuckit, M. A., Cloninger, R., Nurnberger, J., Crowe, R. & Bloom, F. E. (1998). Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalography and Clinical Neurophysiology, 108(3), 244-50. PMID: 9607513.

Rohrbaugh, J. W., Dunham, D. N., Stewart, P. A., Bauer, L. O., Kuperman, S., O'Connor, S. J., Porjesz, B. & Begleiter, H. (1997). Slow brain potentials in a visual-spatial memory task: topographic distribution and inter-laboratory consistency. International Journal of Psychophysiology, 25(2), 111-22. PMID: 9101336.

Koziol, T., Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J. (1997). A graphical technique for displaying correlation matrices. Journal of the American Statistical Association, 51, 301-304.

Polich, J., Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Porjesz, B., Rohrbaugh, J. & Begleiter, H. (1997). P300 topography of amplitude/latency correlations. Brain Topography, 9(4), 275-82. PMID: 9217986.

Kuperman, S., Johnson, B., Arndt, S., Lindgren, S. & Wolraich, M. (1996). Quantitative EEG differences in a nonclinical sample of children with ADHD and undifferentiated ADD. Journal of the American Academy of Child and Adolescent Psychiatry, 35(8), 1009-17. PMID: 8755797.

Alexander, J. E., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Rohrbaugh, J., Porjesz, B., Begleiter, H. & Polich, J. (1996). Hemispheric differences for P300 amplitude from an auditory oddball task. International Journal of Psychophysiology, 21(2-3), 189-96. PMID: 8792206.

Porjesz, B., Begleiter, H., Litke, A., Bauer, L. O., Kuperman, S., O'Connor, S. J. & Rohrbaugh, J. (1996). Visual P3 as a Potential Phenotypic Marker for Alcoholism: Evidence from the COGA National Project. In Ogura , Koga , Shimokochi (Eds.) Recent Advances in Event-Related Brain Potential Research. pp. 539-549. Elsevier Science BV, Amsterdam.

Alexander, J. E., Porjesz, B., Bauer, L. O., Kuperman, S., Morzorati, S., O'Connor, S. J., Rohrbaugh, J., Begleiter, H. & Polich, J. (1995). P300 hemispheric amplitude asymmetries from a visual oddball task. Psychophysiology, 32(5), 467-75. PMID: 7568641.

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S. & Rohrbaugh, J. (1995). Multi-center N400 ERP consistency using a primed and unprimed word paradigm. Electroencephalography and Clinical Neurophysiology, 94(6), 462-70. PMID: 7607100.

Barrickman, L. L., Perry, P. J., Allen, A. J., Kuperman, S., Arndt, S. V., Herrmann, K. J. & Schumacher, E. (1995). Bupropion versus methylphenidate in the treatment of attention-deficit hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 34(5), 649-57. PMID: 7775360.

Cohen, H. L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S. J., Rohrbaugh, J. & Begleiter, H. (1994). Visual P300: an interlaboratory consistency study. Alcohol, 11(6), 583-7. PMID: 7865162.

Alexander, J. E., Polich, J., Bloom, F. E., Bauer, L. O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S. J., Porjesz, B. & Begleiter, H. (1994). P300 from an auditory oddball task: inter-laboratory consistency. International Journal of Psychophysiology, 17(1), 35-46. PMID: 7961052.

Lundy, M. S., Pfohl, B. M. & Kuperman, S. (1993). Adult criminality among formerly hospitalized child psychiatric patients. Journal of the American Academy of Child and Adolescent Psychiatry, 32(3), 568-76. PMID: 8496121.

Barrickman, L., Noyes, R., Kuperman, S., Schumacher, E. & Verda, M. (1991). Treatment of attention deficit hyperactivity disorder with fluoxetine: a preliminary trial. Journal of the American Academy of Child and Adolescent Psychiatry, 30(5), 762-7. PMID: 1938791.

Kuperman, S. (1991). Tic Disorders. In Greydanus , Wolraich (Eds.) Behavioral Pediatrics. Springer-Verlag, New York.

Tomasson, K., Kuperman, S. (1990). Bipolar disorder in a prepubescent child. Journal of the American Academy of Child and Adolescent Psychiatry, 29(2), 308-10. PMID: 2324071.

Kuperman, S., Gaffney, G. R., Hamdan-Allen, G., Preston, D. F. & Venkatesh, L. (1990). Neuroimaging in child and adolescent psychiatry. Journal of the American Academy of Child and Adolescent Psychiatry, 29(2), 159-72. PMID: 2182609.

O'Leary, D. S., Kuperman, S., Cohen, G. A. & Andreasen, N. (1990). Schizophrenia and the frontal lobes: Comparison of multiple imaging techniques and neuropsychological testing. (Vols. 16). pp. 1262. Society for Neuroscience Abstracts.

Gaffney, G. R., Kuperman, S., Tsai, L. Y. & Minchin, S. (1989). Forebrain structure in infantile autism. Journal of the American Academy of Child and Adolescent Psychiatry, 28(4), 534-7. PMID: 2768148.

Larsen, C., Kuperman, S. & Smith, R. (1989). Rural Psychiatry. In Dosman , Cockcroft (Eds.) Health, Safety, and Agriculture. CRC Press, Bocaratan, Florida.

Gaffney, G. R., Kuperman, S., Tsai, L. Y. & Minchin, S. (1988). Morphological evidence for brainstem involvement in infantile autism. Biological Psychiatry, 24(5), 578-86. PMID: 3167146.

Kuperman, S., Kramer, J. & Loney, J. (1988). Enzyme activity and behavior in hyperactive children grown up. Biological Psychiatry, 24(4), 375-83. PMID: 3408755.

Kuperman, S., Black, D. W. & Burns, T. L. (1988). Excess mortality among formerly hospitalized child psychiatric patients. Archives of General Psychiatry, 45(3), 277-82. PMID: 3341882.

Kuperman, S., Black, D. W. & Burns, T. L. (1988). Excess suicide among formerly hospitalized child psychiatry patients. The Journal of Clinical Psychiatry, 49(3), 88-93. PMID: 3346202.

Gaffney, G. R., Tsai, L. Y., Kuperman, S. & Minchin, S. (1987). Cerebellar structure in autism. American Journal of Diseases of Children, 141(12), 1330-2. PMID: 3500635.

Noyes, R., Kuperman, S. & Olson, S. B. (1987). Desipramine: a possible treatment for depersonalization disorder. Canadian Journal of Psychiatry, 32(9), 782-4. PMID: 3435887.

Beeghly, J. H., Kuperman, S., Perry, P. J., Wright, G. J. & Tsai, L. Y. (1987). Fenfluramine treatment of autism: relationship of treatment response to blood levels of fenfluramine and norfenfluramine. Journal of Autism and Developmental Disorders, 17(4), 541-8. PMID: 3316172.

Gaffney, G. R., Kuperman, S., Tsai, L. Y., Minchin, S. & Hassanein, K. M. (1987). Midsagittal magnetic resonance imaging of autism. The British Journal of Psychiatry, 151, 831-3. PMID: 3502809.

Kuperman, S., Stewart, M. A. (1987). Use of propranolol to decrease aggressive outbursts in younger patients. Open study reveals potentially favorable outcome. Psychosomatics, 28(6), 315-9. PMID: 3432546.

Kuperman, S., Beeghly, J., Burns, T. & Tsai, L. (1987). Association of serotonin concentration to behavior and IQ in autistic children. Journal of Autism and Developmental Disorders, 17(1), 133-40. PMID: 3571137.

Kuperman, S., Beeghly, J. H., Burns, T. L. & Tsai, L. Y. (1985). Serotonin relationships of autistic probands and their first-degree relatives. Journal of the American Academy of Child Psychiatry, 24(2), 186-90. PMID: 3989161.

Nasrallah, H. A., Kuperman, S., Jacoby, C. G., McCalley-Whitters, M. & Hamra, B. (1983). Clinical correlates of sulcal widening in chronic schizophrenia. Psychiatry Research, 10(4), 237-42. PMID: 6583714.

Nasrallah, H. A., Kuperman, S., Hamra, B. J. & McCalley-Whitters, M. (1983). Clinical differences between schizophrenic patients with and without large cerebral ventricles. The Journal of Clinical Psychiatry, 44(11), 407-9. PMID: 6605965.

Guze,, Earls,, Barret, (Eds.) (1983). 2. Childhood Psychopathology and Development. American Journal of Psychiatry.

Nasrallah, H. A., McCalley-Whitters, M. & Kuperman, S. (1982). Neurological differences between paranoid and nonparanoid schizophrenia: Part I. sensory-motor lateralization. The Journal of Clinical Psychiatry, 43(8), 305-6. PMID: 7096270.

Nasrallah, H. A., Rizzo, M., Damasio, H., McCalley-Whitters, M., Kuperman, S. & Jacoby, C. G. (1982). Neurological differences between paranoid and nonparanoid schizophrenia: Part II. computerized tomographic findings. The Journal of Clinical Psychiatry, 43(8), 307-9. PMID: 7096271.

Nasrallah, H. A., Tippin, J., McCalley-Whitters, M. & Kuperman, S. (1982). Neurological differences between paranoid and nonparanoid schizophrenia: Part III. neurological soft signs. The Journal of Clinical Psychiatry, 43(8), 310-2. PMID: 7096272.

Nasrallah, H. A., Jacoby, C. G., McCalley-Whitters, M. & Kuperman, S. (1982). Cerebral ventricular enlargement in subtypes of chronic schizophrenia. Archives of General Psychiatry, 39(7), 774-7. PMID: 6984642.

Friedhoff, A. J., Chase, T. N. (Eds.) (1982). Advances in Neurology, Vol. 33: Gilles de la Tourette's Syndrome. American Journal of Psychiatry, 140(1534-1535).

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Kuperman, S., Stewart, M. A. (1981). Grief and Depression. In Stewart , Gabel (Eds.) Behavioral Problems in Childhood. Grune and Stratton, Inc. New York, New York.

Nasrallah, H. A., McCalley-Whitters, M., Kuperman, S. & Keelor, K. (1981). Laterality in paranoid and nonparanoid schizophrenia. pp. 32. New Research Abstracts, American Psychiatric Association Annual Meeting.

Nasrallah, H. A., Kuperman, S. & Coryell, W. (1980). Reversal of dexamethasone nonsuppression with sleep deprivation in primary depression. The American Journal of Psychiatry, 137(11), 1463-4. PMID: 7435693.

Kuperman, S., Stewart, M. A. (1979). The diagnosis of depression in children. Journal of Affective Disorders, 1(3), 213-7. PMID: 162504.

Noyes, R., Hoenk, P. R., Kuperman, S. & Slymen, D. J. (1977). Depersonalization in accident victims and psychiatric patients. The Journal of Nervous and Mental Disease, 164(6), 401-7. PMID: 864453.

Perry, P., Kuperman, S. Attention Deficit Hyperactivity Disorder in Children, Adolescents, and Adults. In Koda-Kimble , Young , Alldredge , Cirelli , Guglielmo , Kradjan , Williams (Eds.) Applied Therapueutics, the Clinical Use of Drugs 9th Edition. pp. 81.1-81.9. Lippincott, Williams, & Wilkins, Philadephia.