Sarah Haskell, DO

Portrait
Program Director, Pediatric Critical Care Fellowship
Assistant Professor of Pediatrics - Critical Care

Contact Information

200 Hawkins Dr
Iowa City, IA 52242
319-356-1615

Education

BS, Exercise Science, University of Nebraska
DO, Kansas City University of Medicine and Biosciences
Resident, Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa
Fellow, Pediatric Critical Care, University of Iowa Children's Hospital, Iowa City, Iowa

Licensure and Certifications

Pediatrics Critical Care Medicine, Board Certified
American Board of Pediatrics, Board Certified

Research Summary

Laboratory work is focused on how the fetal environment impacts cardiovascular development and disease. In the United States, currently 10% of pregnant women are treated with selective serotonin reuptake inhibitors (SSRIs). Because SSRIs cross the placenta, the safety of these medications is of concern to the developing fetus. We are currently using an exposure model to investigate the effects of the antidepressant sertraline on cardiac development. My clinical research interest is in optimizing pediatric cardiopulmonary arrest care in both in-patient and out-patient settings. We are currently part of a multi-center study investigating the quality of pediatric resuscitation.

Publications

Haskell, S. E., Atkins, D. L. (2016). Pediatric Out-of-Hospital Cardiac Arrest: Pushing for Progress in Public Response. JAMA pediatrics. PMID: 27837586.

Ansah, D. A., Reinking, B. E., Roghair, R. D. & Haskell, S. E. (2016). Determination of cardiac size and function in a prospective study of SSRI exposed infants. Midwest Pediatric Cardiology Society Annual Meeting; Madison, WI.

Haskell, S. E., Lo, C., Peotta, V. A., Reinking, B. E. & Roghair, R. D. (2016). Maternal SSRI exposure decreases cardiac 5-HT2B receptor expression and Akt phosphorylation in neonatal mice. Pediatric Academic Societies; Baltimore, MD.

Haskell, S. E., Peotta, V., Reinking, B. E., Zhang, C., Zhu, V., Kenkel, E. J. & Roghair, R. D. (2016). Oral estrogen reverses ovariectomy-induced morning surge hypertension in growth-restricted mice. Clinical science (London, England : 1979), 130(8), 613-23. PMID: 26795436.

Haskell, S. E., Lo, C., Volk, K. A., Reinking, B. E. & Roghair, R. D. (2015). Maternal SSRI exposure decreases cardiac 5-HT2B receptor expression and Akt phosphorylation in neonatal mice. Midwest Society for Pediatric Research Annual Meeting; Kansas City, MO.

Haskell, S. E., Lo, C., Volk, K. A., Peotta, V. A., Reinking, B. E. & Roghair, R. D. (2015). Maternal SSRI exposure decreases neonatal cardiomyocyte size and Akt phosphorylation in mice. The Second Annual Neonatal Cardiopulmonary Biology Young Investigators’ Forum; Chicago, IL.

Haskell, S. E., Lo, C., Volk, K. A., Peotta, V. A., Reinking, B. E. & Roghair, R. D. (2014). Maternal SSRI exposure down-regulates cardiac 5-HT2B expression and decreases stroke volumes in mice. The Neonatal Cardiopulmonary Biology Young Investigators’ Forum; Chicago, IL.

Engelstad, H. J., Roghair, R. D., Calarge, C. A., Colaizy, T. T., Stuart, S. & Haskell, S. E. (2014). Perinatal outcomes of pregnancies complicated by maternal depression with or without SSRI therapy. Neonatology, 105(2), 149-154.

Haskell, S. E., Peotta, V. A., Reinking, B. E., Herman, G. H. & Roghair, R. D. (2013). Impact of neonatal sertraline exposure on the post-myocardial infarction outcomes of adult male mice. Journal of Cardiovascular Pharmacology, 62(5), 479-484.

Haskell, S. E., Lo, C., Volk, K. A., Peotta, V. A., Reinking, B. E. & Roghair, R. D. (2013). The impact of SSRI exposure on cardiac development. Child Health Research Career Development Annual Retreat; Aurora, CO.

Englestad, H. J., Roghair, R. D., Calarge, C. A., Colaizy, T. C. & Haskell, S. E. (2013). Perinatal outcomes of pregnancies complicated by maternal depression with or without SSRI therapy. Pediatric Academic Societies; Washington D.C.

Haskell, S., Hermann, G. M., Reinking, B., Volk, K. A., Peotta, V. A., Zhu, V. & Roghair, R. (2013). Sertraline exposure leads to a small left heart syndrome in adult male mice. Pediatric Research, 73(3), 286-293.

Kummet, G. J., Haskell, S., Hermann, G. M., Ni, C., Volk, K. A., Younes, A. K., Miller, A. K. & Roghair, R. (2012). Neonatal SSRI exposure programs a hypermetabolic state in adult mice. Journal of Nutrition and Metabolism, 431574.

Haskell, S. E. (2012). Pediatric Critical Care Reference Guide (PICU Charts). Iowa City, IA: University of Iowa Stead Family Children's Hospital.

Haskell, S., Zhang, R., Hermann, G. M., Kummet, G., Ni, C., Cushman, T. R. & Roghair, R. (2011). Neonatal SSRI exposure increases sympathetic tone in adult mice. Pediatric Academic Societies Meeting; Denver, CO.

Haskell, S., Hermann, G. M., Zhang, R., Reinking, B. & Roghair, R. (2011). Neonatal sertraline exposure impairs cardiac development and increases sympathetic tone in mice. (Vols. 2). (1) Journal of Developmental Origins of Health and Disease.

Haskell, S., Zhang, Z., Hermann, G. M., Ni, C., Cushman, T. R. & Roghair, R. (2010). Neonatal Sertraline exposure increases adult sympathetic tone. Midwest Society for Pediatric Research Meeting; Iowa City, IA.

Haskell, S., Hermann, G. M. & Roghair, R. (2010). Sertraline exposure and the programming of adult cardiovascular disease. Pediatric Academic Sciences Meeting; Vancouver, Canada.

Hermann, G. M., Dallas, L. M., Haskell, S. & Roghair, R. (2010). Neonatal macrosomia is an independent risk factor for adult metabolic syndrome. Neonatology, 98(3), 238-244.

Haskell, S. E., Hermann, G. M. & Roghair, R. D. (2010). Sertraline exposure and the programming of adult cardiovascular disease. University of Iowa Heath Sciences Research Week.

Haskell, S. E., Hermann, G. M. & Roghair, R. D. (2010). Sertraline exposure and the programming of adult cardiovascular disease. University of Iowa Pediatric Research Day.

Haskell, S., Atkins, D. (2010). Defibrillation in children. Journal of Emergencies, Trauma, and Shock, 3, 261-6.

Haskell, S. E. (2010). PICU Handbook : a practical guide to surviving your PICU rotations. (Revised) Iowa City, IA: University of Iowa Stead Family Children's Hospital.

Haskell, S., Post, M., Cram, P. M. & Atkins, D. (2009). Community public access sites: compliance with American Heart Association recommendations. Resuscitation, 80(8), 854-858.

Haskell, S., Kenney, M. A., Patel, S. S., Sanddal, T. L., Altenhofen, K. L., Sanddal, N. D. & Atkins, D. (2008). Awareness of guidelines for use of automated external defibrillators in children within emergency medical services. Resuscitation, 76(3), 354-359.

Haskell, S. E., Kenney, M. A., Sanddal, T. L., Altenhofen, K. L., Sanndal, N. D. & Atkins, D. L. (2007). Awareness of guidelines for use of automated external defibrillators in children within emergency medical services. American Heart Association Resuscitation Science Symposium; Orlando, FL.

Haskell, S. E., Kenney, M. A., Patel, S., Sanddal, T. L. & Altenhofen, K. L. (2007). Awareness of guidelines for use of automated external defibrillators in children within emergency medical services. University of Iowa Pediatric Research Day.