Research by Investigator

List organized by investigator's last name

 A-B-C : D-E-F : G-H-I : J-K-L : M-N-O : P-Q-R : S-T-U : V-W-X-Y-Z

Investigator Initiative
Nancy Andreasen, MD, PhD - Brain Imaging in Major Psychoses: Examining Structural and Functional Connectivity

- MOSAIC: The Management of Schizophrenia In Clinical Practice

- Research Training in the Major Psychoses and Clinical Neurobiology

- Creativity, Schizophrenia, and Mood Disorders: Interrelationships and Neural Mechanisms

- Identifying the Brain Mechanisms Underlying Paranoia

- Relapse Prevention and Progressive Brain Change in Schizophrenia

- MOSAIC Site: The Management of Schizophrenia in Clinical Practice
Stephan Arndt, PhD Iowa Consortium for Substance Abuse Research and Evaluation

- Treatment Strategy for Alcohol Use Disorders in Veterans with Traumatic Brain Injury
Allan Andersen, MD -Risk factors for immune-related disease in individuals with substance use disorders
Donald Black, MD - Treatment of Male and Female Incarcerated Offenders with Borderline Personality Disorder in the Iowa Prison System Using the STEPPS Program
William Coryell, MD - An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression 

- A Randomized, Double-blind, Multicenter, Active-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Subjects with Treatment-resistant Depression 

- A Prospective, Longitudinal, Observational Study to Evaluate Potential Predictors of Relapse in Subjects With Major Depressive Disorder Who Have Responded to Antidepressant Treatment

- A Randomized, Multicenter, Crossover Study to Assess the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Subjects with Major Depressive Disorder 
Eric Epping, MD, PhD - Characterization of Schizophrenia Genetic Risk Factors from Whole Exome Sequencing

- Identification of DNA Sequence Mutations in Regions of Copy Number Variation in Schizophrenia Patients

- Creatine Safety, Tolerability, Efficacy in Huntington's Disease
Jess Fiedorowicz, MD, PhD

Jess G. Fiedorowicz Laboratory

- Antipsychotics and Vascular Function in Bipolar Disorder

- Identifying Patients at Increased Risk of Heart Disease from Antipsychotic Medications

Beng Choon Ho, MD - Adolescent Cannabis Use, Complex Brain Network Connectivity & Schizophrenia Risk

- High-throughput Combined Assay of Multiplex Serum Biomarkers for Schizophrenia
Karin Hoth, PhD



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Karin Hoth Lab

-Cardiopulmonary Mechanisms Affecting Cognition in COPD

Hans Johnson, PhD Brain Imaging Analysis: SINAPSE 

- National Alliance for Medical Image Computing (NAMIC)

- Track HD and Track-On HD

- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease

- 4D Shape Analysis for Modeling Spatiotemporal Change Trajectories in Huntington's Disease
Samuel Kuperman, MD - Collaborative Study on the Genetics of Alcoholism (COGA)

- Collaborative Genomic Studies of Tourette Disorder
Doug Langbehn, MD, PhD - Track HD and Track-On HD

- Statistical Design of Huntington's Disease Studies and the Analysis and Modeling of HD Data
Jeffrey Long, PhD  - Functional Connectivity in Premanifest Huntington's Disease (co-investigator)

- Network of Excellence in Neuroscience Clinical Trials (NEXT)-DCC (co-investigator)

- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease (co-investigator)

- Neurobiological Predictors of Huntington's Disease (PREDICT-HD) (co-investigator)
Jacob Michaelson, PhD 

Jacob Michaelson Laboratory

- Genetics of neurodevelopmental conditions (ASD, ID, DD)

- Gender differences in neurodevelopmental conditions

- Genetics of language ability

- Machine learning to improve the interpretation of non-coding genetic variants

- Functional and regulatory genomics in the brain

Del Miller, MD, PharmD

ACLAIMS (A Comparison of Long-Acting Injectiable Medications for Schizophrenia)

Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Persistent, Predominant Negative Symptoms

Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Sub-Optimally Controlled Symptoms

Alzheimer's Research

David Moser, PhD - Vascular Function, Cognition, and Brain MRI in Atherosclerotic Vascular Disease
Thomas Nickl-Jockschat, MD -Brain structural changes in psychiatric disorders, such as schizophrenia or autism spectrum disorders
Peg Nopoulos, MD

Peg Nopoulos Laboratory

Kids HD and Kids JHD

- Brain Structure, Function, and Growth in Children with Huntington's Disease

- Brain Structure and Function in Children at Risk for Huntington's Disease

- Brain Structure and Function in Children with Oral Clefts

Daniel O'Leary, PhD



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Cognitive Brain Development Laboratory

- Marijuana Use and Schizophrenia

- Brain Development in Adolescents with Genetics Risk Factors for Alcoholism

-The effects of binge drinking in College students on brain structure and function
Krystal Parker, PhD

Parker Lab

-Cerebellar contribution to cognition 

-Potential for cerebellar stimulation to rescue cognitive impairments in humans with schizophrenia

Jane Paulsen, PhD

University of Iowa Huntington's Disease Society of America Center of Excellence

-PREDICT-HD

- Neurobiological Predictors of Huntington's Disease (Predict-HD)

- Validation of the HD-Quality of Life Measure

- Functional Connectivity in Premanifest Huntington's Disease

Robert Philibert, MD, PhD - The Effects of Smoking on DNA Methylation in Primary Human Lymphocyte

- Examination of Genetic and GxE Effects in the Family and Community Health Studies

- Factors Influencing the Health Behaviors of Young African American Adults

- Using DNA Methylation to Determine Recent Alcohol Consumption Patterns

- A Transdiciplinary Center Focused on Rural African American Families
Gen Shinozaki, MD, FAPM Gen Shinozaki Laboratory
Megan M Smith, PhD - Cognition and Psychoneuroimmunology in Multiple Sclerosis
Hanna E. Stevens, MD, PhD Psychiatry and Early Neurobiological Development Laboratory
Scott Stuart, MD Interpersonal Psychotherapy Institute

- Placebo-controlled Trial of Sertraline and IPT for Postpartum Depression

- Optimizing Fidelity of Interpersonal Psychotherapy for Depression

- Web-based Cognitive Behavioral Intervention
Beth Troutman, PhD Parent-Child Interaction Therapy  
Jatin Vaidya, PhD Cognitive Brain Development Laboratory

- Attentional Capacity in Adolescence
Carolyn Turvey, PhD - Combined Illness Management and Psychotherapy in Treating Depressed Elders

- My HealtheVet Project: Blue Button Feature Evaluation

- DRI Training: the Conduct of Psychosocial Care Intervention
Ellen van der Plas, PhD

-Neurodevelopmental aspects of childhood cancer

-Cognitive and behavioral functioning in survivors of childhood leukemia

-Neuroimaging as a translational tool for identifying neurodevelopmental mechanisms of adverse, functional outcomes and quality of life

-Transdisciplinary, team research that integrates basic and applied sciences

Thomas Wassink, MD Thomas Wassink Laboratory

- A Family-Genetic Study of Language in Autism
John Wemmie, MD, PhD John Wemmie Laboratory

- Brain pH and Acid Sensing in Depression Related Behavior

- Modeling CO2‐Evoked Fear in Mice: Role of Acid‐Sensing Ion Channels

- Regulation of Cerebral Blood Flow by Acid-Sensing Ion Channels (ASICs)

- Anti-depressant Effects of Targeting ASIC1a in the Nucleus Accumbens
Aislinn Williams, MD, PhD

Williams Lab

-Developmental pathways involved in neuropsychiatric disease

-Voltage-gated calcium channel genes

Virginia Willour, PhD



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- Attempted Suicide Candidate Gene Resequencing

- Suicide Epigenetics

- Genetic Risk Factor for Suicidal Behavior