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Hildegard Janouschek, MD

Assistant Professor of Psychiatry

Introduction

The Janouschek lab is interested in understanding the development of fear-related behaviors from a developmental perspective. Our current projects focus on acid-sensing ion channels, brain-acidity and the emergence of different fear related behaviors during development.

In another project we, investigate the influence of cerebellar manipulations on fear related behaviors and memory.

In order to answer our questions we use behavioral testing, genetic manipulations, molecular biology, biochemistry and neuropathology.

Current Positions

  • Assistant Professor of Psychiatry

Education

  • MD in Medicine, University of Regensburg, Regensburg, Germany
  • Resident in Department of Psychiatry and Psychotherapy, RWTH Aachen University
  • Resident in Department of Neurology, RWTH Aachen University
  • Resident, RWTH Aachen University
  • Consultant in Department of Psychiatry and Psychotherapy, Aachen University
  • Resident in Department of Neurology, RWTH Aachen University
  • Fellowship in Neuro-Critical Care, RWTH Aachen

Center, Program and Institute Affiliations

Selected Publications

  • Janouschek, H., Chase, H.W., Sharkey, R.J., Peterson, Z.J., Camilleri, J.A., Abel, T., Eickhoff, S.B., & Nickl-Jockschat, T. (2021) The functional neural architecture of dysfunctional reward processing in autism. NeuroImage: Clinical 31. DOI: 10.1016/j.nicl.2021.102700
  • Janouschek, H., Camilleri, J. A., Peterson, Z., Sharkey, R. J., Eickoff, C. R., Grozinger, M., Eickhoff, S. B., & Nickl-Jockschat, T. (2021) Meta-analytic Evidence for Volume Increases in the Medial Temporal Lobe After Electroconvulsive Therapy. Biological Psychiatry 90 (4) 11-17. DOI: 10.1016/j.biopsych.2021.03.024
  • Janouschek, H., Langbehn, D. R., Nickl-Jockschat, T. & Grozinger, M. (2020). The impact of seizure quality on ect treatment efficacy. Psychiatry Research 293. DOI: 10.1016/j.psychres.2020.113466. PMID: 33198041.
  • Janouschek, H., Eickhoff, C. R., Mühleisen, T. W., Eickhoff, S. B. & Nickl-Jockschat, T. (2018). Using coordinate-based meta-analyses to explore structural imaging genetics. Brain structure & function. DOI: 10.1007/s00429-018-1670-9. PMID: 29730826.
  • Veselinović, T., Vernaleken, I., Janouschek, H., Cumming, P., Paulzen, M., Mottaghy, F. M. & Gründer, G. (2018). The role of striatal dopamine D2/3 receptors in cognitive performance in drug-free patients with schizophrenia. Psychopharmacology. DOI: 10.1007/s00213-018-4916-6. PMID: 29717334.
  • Nickl-Jockschat, T., Janouschek, H., Eickhoff, S. B. & Eickhoff, C. R. (2015). Lack of meta-analytic evidence for an impact of COMT Val158Met genotype on brain activation during working memory tasks. (Vols. 78). (11), pp. e43-6. Biological psychiatry. DOI: 10.1016/j.biopsych.2015.02.030. PMID: 25861704.
  • Veselinović, T., Vernaleken, I., Janouschek, H., Kellermann, T., Paulzen, M., Cumming, P. & Gründer, G. (2015). Effects of anticholinergic challenge on psychopathology and cognition in drug-free patients with schizophrenia and healthy volunteers. Psychopharmacology 232 (9) 1607-17. DOI: 10.1007/s00213-014-3794-9. PMID: 25373869.
  • Janouschek, H. & Nickl-Jockschat, T. (2014). The mechanism of action of ECT. In Di Pauli, J., Nickl-Jockschat, T. & Grozinger, M. (Eds.) Elektrokonvulsionstherapie kompakt. Germany.
  • Janouschek, H., Nickl-Jockschat, T., Haeck, M., Gillmann, B. & Grözinger, M. (2013). Comparison of methohexital and etomidate as anesthetic agents for electroconvulsive therapy in affective and psychotic disorders. Journal of psychiatric research 47 (5) 686-93. DOI: 10.1016/j.jpsychires.2012.12.019. PMID: 23399487.
  • Neuner, I., Arrubla, J., Ehlen, C., Janouschek, H., Nordt, C., Fimm, B., Schneider, F., Shah, N. J. & Kawohl, W. (2012). Fine motor skills in adult Tourette patients are task-dependent. BMC neurology 12 120. DOI: 10.1186/1471-2377-12-120. PMID: 23057645. PMCID: PMC3527195.