Thomas Nickl-Jockschat, MD

Associate Professor of Psychiatry

Contact Information

Primary Office
2318 Pappajohn Biomedical Discovery Building
169 Newton Rd
Iowa City, IA 52242


University of Regensburg
Resident, RWTH Aachen University Department of Psychiatry and Psychotherapy
Resident, RWTH Aachen University Department of Neurology


Camilleri, J. A., Hoffstaedter, F., Zavorotny, M., Zöllner, R., Wolf, R. C., Thomann, P., Redlich, R., Opel, N., Dannlowski, U., Groezinger, M., Demirakca, T., Sartorius, A., Eickhoff, S. B. & Nickl-Jockschat, T. (2019). Electroconvulsive therapy modulates grey matter increase in a hub of an affect processing network. NeuroImage. Clinical, 25, 102114. PMID: 31884221.

Wong, T. Y., Radua, J., Pomarol-Clotet, E., Salvador, R., Albajes-Eizagirre, A., Solanes, A., Canales-Rodriguez, E. J., Guerrero-Pedraza, A., Sarro, S., Kircher, T., Nenadic, I., Krug, A., Grotegerd, D., Dannlowski, U., Borgwardt, S., Riecher-Rössler, A., Schmidt, A., Andreou, C., Huber, C. G., Turner, J., Calhoun, V., Jiang, W., Clark, S., Walton, E., Spalletta, G., Banaj, N., Piras, F., Ciullo, V., Vecchio, D., Lebedeva, I., Tomyshev, A. S., Kaleda, V., Klushnik, T., Filho, G. B., Zanetti, M. V., Serpa, M. H., Penteado Rosa, P. G., Hashimoto, R., Fukunaga, M., Richter, A., Krämer, B., Gruber, O., Voineskos, A. N., Dickie, E. W., Tomecek, D., Skoch, A., Spaniel, F., Hoschl, C., Bertolino, A., Bonvino, A., Di Giorgio, A., Holleran, L., Ciufolini, S., Marques, T. R., Dazzan, P., Murray, R., Lamsma, J., Cahn, W., van Haren, N., Díaz-Zuluaga, A. M., Pineda-Zapata, J. A., Vargas, C., López-Jaramillo, C., van Erp TGM,, Gur, R. C. & Nickl-Jockschat, T. (2019). An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium. Psychological medicine, 1-12. PMID: 31615588.

Neugebauer, K., Hammans, C., Wensing, T., Kumar, V., Grodd, W., Mevissen, L., Sternkopf, M. A., Novakovic, A., Abel, T., Habel, U. & Nickl-Jockschat, T. (2019). Nerve Growth Factor Serum Levels Are Associated With Regional Gray Matter Volume Differences in Schizophrenia Patients. Frontiers in psychiatry, 10, 275. PMID: 31105606.

J, C., K, P., S, W., K, S. & B, E. S. (In Press). Neurobiological divergence of the positive and negative schizophrenia subtypes identified upon a new factor-structure of psychopathology using non-negative factorization: An international machine-learning study. Biol Psychiatry.

Sartorius, A., Demirakca, T., Böhringer, A., von Clemm Hohenberg, C., Aksay, S. S., Bumb, J. M., Kranaster, L., Nickl-Jockschat, T., Grözinger, M., Thomann, P. A., Wolf, R. C., Zwanzger, P., Dannlowski, U., Redlich, R., Zavorotnyy, M., Zöllner, R., Methfessel, I., Besse, M., Zilles, D. & Ende, G. (2018). Electroconvulsive therapy induced gray matter increase is not necessarily correlated with clinical data in depressed patients. Brain stimulation. PMID: 30554869.

Wong, T. Y., Sid, A., Wensing, T., Eickhoff, S. B., Habel, U., Gur, R. C. & Nickl-Jockschat, T. (2018). Neural networks of aggression: ALE meta-analyses on trait and elicited aggression. Brain structure & function. PMID: 30291479.

Kumar, V. J., Grissom, N. M., McKee, S. E., Schoch, H., Bowman, N., Havekes, R., Kumar, M., Pickup, S., Poptani, H., Reyes, T. M., Hawrylycz, M., Abel, T. & Nickl-Jockschat, T. (2018). Linking spatial gene expression patterns to sex-specific brain structural changes on a mouse model of 16p11.2 hemideletion. Translational psychiatry, 8(1), 109. PMID: 29844452.

Janouschek, H., Eickhoff, C. R., Mühleisen, T. W., Eickhoff, S. B. & Nickl-Jockschat, T. (2018). Using coordinate-based meta-analyses to explore structural imaging genetics. Brain structure & function. PMID: 29730826.

Chase, H. W., Loriemi, P., Wensing, T., Eickhoff, S. B. & Nickl-Jockschat, T. (2018). Meta-analytic evidence for altered mesolimbic responses to reward in schizophrenia. Human brain mapping. PMID: 29573046.

Groezinger, M., Conca, A., Nickl-Jockschat, T. & Di Pauli, J. (2018). La terapia elettroconvulsivante. Pacini Medicina.

Grissom, N. M., McKee, S. E., Schoch, H., Bowman, N., Havekes, R., O'Brien, W. T., Mahrt, E., Siegel, S., Commons, K., Portfors, C., Nickl-Jockschat, T., Reyes, T. M. & Abel, T. (2017). Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders. Molecular psychiatry. PMID: 29038598.

Wensing, T., Cieslik, E. C., Müller, V. I., Hoffstaedter, F., Eickhoff, S. B. & Nickl-Jockschat, T. (2017). Neural correlates of formal thought disorder: An activation likelihood estimation meta-analysis. Human brain mapping, 38(10), 4946-4965. PMID: 28653797.

Genon, S., Wensing, T., Reid, A., Hoffstaedter, F., Caspers, S., Grefkes, C., Nickl-Jockschat, T. & Eickhoff, S. B. (2017). Searching for behavior relating to grey matter volume in a-priori defined right dorsal premotor regions: Lessons learned. NeuroImage, 157, 144-156. PMID: 28552730.

Nickl-Jockschat, T., Palomero Gallagher, N., Kumar, V., Hoffstaedter, F., Brügmann, E., Habel, U., Eickhoff, S. B. & Grözinger, M. (2016). Are morphological changes necessary to mediate the therapeutic effects of electroconvulsive therapy?. Eur Arch Psychiatry Clin Neurosci, 266(3), 261-267.

Abel, T., Nickl-Jockschat, T. (Eds.) (2016). The Neurobiology of Schizophrenia.

Vogel, K., Timmers, I., Kumar, V., Nickl-Jockschat, T., Bastiani, M., Roebroek, A., Herpertz-Dahlmann, B., Konrad, K., Goebel, R. & Seitz, J. (2016). White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study. Clinical neuroimaging. DOI: 10.1016/j.nicl.2016.04.002.

Angelakos, C. C., Watson, A. J., O'Brien, W. T., Krainock, K. S., Nickl-Jockschat, T. & Abel, T. (2016). Hyperactivity and male-specific sleep deficits in the 16p11.2 deletion mouse model of autism.

Nickl-Jockschat, T., Janouschek, H., Eickhoff, S. B. & Eickhoff, C. R. (2015). Lack of meta-analytic evidence for an impact of COMT Val158Met genotype on brain activation during working memory tasks. (Vols. 78). (11), pp. e43-6. Biological psychiatry. PMID: 25861704.

Nickl-Jockschat, T., Rottschy, C., Thommes, J., Schneider, F., Laird, A. R., Fox, P. T. & Eickhoff, S. B. (2015). Neural networks related to dysfunctional face processing in autism spectrum disorder. Brain structure & function, 220(4), 2355-71. PMID: 24869925.

Nickl-Jockschat, T., Stöcker, T., Krug, A., Markov, V., Maximov, I. I., Huang, R., Schneider, F., Habel, U., Eickhoff, S. B., Zerres, K., Nöthen, M. M., Rietschel, M., Jon Shah, N., Treutlein, J. & Kircher, T. (2015). Genetic variation in the G72 gene is associated with increased frontotemporal fiber tract integrity. European archives of psychiatry and clinical neuroscience, 265(4), 291-301. PMID: 25031104.

Nickl-Jockschat, T., Stöcker, T., Krug, A., Markov, V., Huang, R., Schneider, F., Habel, U., Eickhoff, S. B., Zerres, K., Nöthen, M. M., Treutlein, J., Rietschel, M., Shah, N. J. & Kircher, T. (2014). A Neuregulin-1 schizophrenia susceptibility variant causes perihippocampal fiber tract anomalies in healthy young subjects. Brain and behavior, 4(2), 215-26. PMID: 24683514.

Michel, T. M., Käsbauer, L., Gsell, W., Jecel, J., Sheldrick, A. J., Cortese, M., Nickl-Jockschat, T., Grünblatt, E. & Riederer, P. (2014). Aldehyde dehydrogenase 2 in sporadic Parkinson's disease. Parkinsonism & related disorders, 20 Suppl 1, S68-72. PMID: 24262192.

Loh, N., Nickl-Jockschat, T., Sheldrick, A. J. & Grözinger, M. (2013). Accessibility, standards and challenges of electroconvulsive therapy in Western industrialized countries: a German example. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 14(6), 432-40. PMID: 22409536.

Greimel, E., Nehrkorn, B., Schulte-Rüther, M., Fink, G. R., Nickl-Jockschat, T., Herpertz-Dahlmann, B., Konrad, K. & Eickhoff, S. B. (2013). Changes in grey matter development in autism spectrum disorder. Brain structure & function, 218(4), 929-42. PMID: 22777602.

Janouschek, H., Nickl-Jockschat, T., Haeck, M., Gillmann, B. & Grözinger, M. (2013). Comparison of methohexital and etomidate as anesthetic agents for electroconvulsive therapy in affective and psychotic disorders. Journal of psychiatric research, 47(5), 686-93. PMID: 23399487.

Nickl-Jockschat, T., Habel, U., Michel, T. M., Manning, J., Laird, A. R., Fox, P. T., Schneider, F. & Eickhoff, S. B. (2012). Brain structure anomalies in autism spectrum disorder--a meta-analysis of VBM studies using anatomic likelihood estimation. Human brain mapping, 33(6), 1470-89. PMID: 21692142.

Nickl-Jockschat, T., Stöcker, T., Markov, V., Krug, A., Huang, R., Schneider, F., Habel, U., Zerres, K., Nöthen, M. M., Treutlein, J., Rietschel, M., Shah, N. J. & Kircher, T. (2012). The impact of a Dysbindin schizophrenia susceptibility variant on fiber tract integrity in healthy individuals: a TBSS-based diffusion tensor imaging study. NeuroImage, 60(2), 847-53. PMID: 22019876.

Nickl-Jockschat, T., Kleiman, A., Schulz, J. B., Schneider, F., Laird, A. R., Fox, P. T., Eickhoff, S. B. & Reetz, K. (2012). Neuroanatomic changes and their association with cognitive decline in mild cognitive impairment: a meta-analysis. Brain structure & function, 217(1), 115-25. PMID: 21667303.

Nickl-Jockschat, T., Schneider, F., Pagel, A. D., Laird, A. R., Fox, P. T. & Eickhoff, S. B. (2011). Progressive pathology is functionally linked to the domains of language and emotion: meta-analysis of brain structure changes in schizophrenia patients. European archives of psychiatry and clinical neuroscience, 261 Suppl 2, S166-71. PMID: 21909731.

Nickl-Jockschat, T., Michel, T. M. (2011). [Genetic and brain structure anomalies in autism spectrum disorders. Towards an understanding of the aetiopathogenesis?]. Der Nervenarzt, 82(5), 618-27. PMID: 20407737.

Nickl-Jockschat, T., Michel, T. M. (2011). The role of neurotrophic factors in autism. Molecular psychiatry, 16(5), 478-90. PMID: 20938434.

Eickhoff, S. B., Nickl-Jockschat, T. & Kurth, F. (2010). [Meta-analyses in clinical brain research]. Der Nervenarzt, 81(1), 32-8. PMID: 20066395.

Baumann, F., Leukel, P., Doerfelt, A., Beier, C. P., Dettmer, K., Oefner, P. J., Kastenberger, M., Kreutz, M., Nickl-Jockschat, T., Bogdahn, U., Bosserhoff, A. K. & Hau, P. (2009). Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro-oncology, 11(4), 368-80. PMID: 19033423.

Nickl-Jockschat, T., Rietschel, M. & Kircher, T. (2009). [Correlations between risk gene variants for schizophrenia and brain structure anomalies]. Der Nervenarzt, 80(1), 40-2, 44-6, 48 passim. PMID: 18820892.

Nickl-Jockschat, T., Paulzen, M., Schneider, F. & Grözinger, M. (2009). Drug interaction can lead to undetectable serum concentrations of quetiapine in the presence of carbamazepine. (Vols. 32). (1), pp. 55. Clinical neuropharmacology. PMID: 19471186.

Nickl-Jockschat, T., Kunert, H. J., Herpertz-Dahlmann, B. & Grözinger, M. (2008). Psychiatric symptoms in a patient with Wolfram syndrome caused by a combination of thalamic deficit and endocrinological pathologies. Neurocase, 15(1), 47-52. PMID: 19090413.

Arslan, F., Bosserhoff, A. K., Nickl-Jockschat, T., Doerfelt, A., Bogdahn, U. & Hau, P. (2007). The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2. British journal of cancer, 96(10), 1560-8. PMID: 17453002.

Nickl-Jockschat, T., Arslan, F., Doerfelt, A., Bogdahn, U., Bosserhoff, A. & Hau, P. (2007). An imbalance between Smad and MAPK pathways is responsible for TGF-beta tumor promoting effects in high-grade gliomas. International journal of oncology, 30(2), 499-507. PMID: 17203233.