Research by Investigator

List organized by investigator's last name

 A-B-C : D-E-F : G-H-I : J-K-L : M-N-O : P-Q-R : S-T-U : V-W-X-Y-Z

Investigator Initiative
Nancy Andreasen, MD, PhD - Brain Imaging in Major Psychoses: Examining Structural and Functional Connectivity

- MOSAIC: The Management of Schizophrenia In Clinical Practice

- Research Training in the Major Psychoses and Clinical Neurobiology

- Creativity, Schizophrenia, and Mood Disorders: Interrelationships and Neural Mechanisms

- Identifying the Brain Mechanisms Underlying Paranoia

- Relapse Prevention and Progressive Brain Change in Schizophrenia

- MOSAIC Site: The Management of Schizophrenia in Clinical Practice
Stephan Arndt, PhD Iowa Consortium for Substance Abuse Research and Evaluation

- Treatment Strategy for Alcohol Use Disorders in Veterans with Traumatic Brain Injury
Allan Andersen, MD -Risk factors for immune-related disease in individuals with substance use disorders
Donald Black, MD - Treatment of Male and Female Incarcerated Offenders with Borderline Personality Disorder in the Iowa Prison System Using the STEPPS Program
William Coryell, MD - An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression 

- A Randomized, Double-blind, Multicenter, Active-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Subjects with Treatment-resistant Depression 

- A Prospective, Longitudinal, Observational Study to Evaluate Potential Predictors of Relapse in Subjects With Major Depressive Disorder Who Have Responded to Antidepressant Treatment

- A Randomized, Multicenter, Crossover Study to Assess the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Subjects with Major Depressive Disorder 
Eric Epping, MD, PhD - Characterization of Schizophrenia Genetic Risk Factors from Whole Exome Sequencing

- Identification of DNA Sequence Mutations in Regions of Copy Number Variation in Schizophrenia Patients

- Creatine Safety, Tolerability, Efficacy in Huntington's Disease
Jess Fiedorowicz, MD, PhD

Jess G. Fiedorowicz Laboratory

- Antipsychotics and Vascular Function in Bipolar Disorder

- Identifying Patients at Increased Risk of Heart Disease from Antipsychotic Medications

Michael Flaum, MD Iowa Consortium for Mental Health
Beng Choon Ho, MD - Adolescent Cannabis Use, Complex Brain Network Connectivity & Schizophrenia Risk

- High-throughput Combined Assay of Multiplex Serum Biomarkers for Schizophrenia
Karin Hoth, PhD



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Karin Hoth Lab

-Cardiopulmonary Mechanisms Affecting Cognition in COPD

Hans Johnson, PhD Brain Imaging Analysis: SINAPSE 

- National Alliance for Medical Image Computing (NAMIC)

- Track HD and Track-On HD

- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease

- 4D Shape Analysis for Modeling Spatiotemporal Change Trajectories in Huntington's Disease
Robin Kopelman, MD, MPH - Project LAUNCH
Samuel Kuperman, MD - Collaborative Study on the Genetics of Alcoholism (COGA)

- Collaborative Genomic Studies of Tourette Disorder
Doug Langbehn, MD, PhD - Track HD and Track-On HD

- Statistical Design of Huntington's Disease Studies and the Analysis and Modeling of HD Data
Jeffrey Long, PhD  - Functional Connectivity in Premanifest Huntington's Disease (co-investigator)

- Network of Excellence in Neuroscience Clinical Trials (NEXT)-DCC (co-investigator)

- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease (co-investigator)

- Neurobiological Predictors of Huntington's Disease (PREDICT-HD) (co-investigator)
Jacob Michaelson, PhD   Molecular Psychiatry Division

 Jacob Michaelson Laboratory

- Genetics of neurodevelopmental conditions (ASD, ID, DD)

- Gender differences in neurodevelopmental conditions

- Genetics of language ability

- Machine learning to improve the interpretation of non-coding genetic variants

- Functional and regulatory genomics in the brain
Del Miller, MD, PharmD - ACLAIMS (A Comparison of Long-Acting Injectiable Medications for Schizophrenia)

- Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Persistent, Predominant Negative Symptoms

- Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Sub-Optimally Controlled Symptoms
David Moser, PhD - Vascular Function, Cognition, and Brain MRI in Atherosclerotic Vascular Disease
Peg Nopoulos, MD Peg Nopoulos Laboratory

- Brain Structure, Function, and Growth in Children with Huntington's Disease

- Brain Structure and Function in Children at Risk for Huntington's Disease

- Brain Structure and Function in Children with Oral Clefts
Daniel O'Leary, PhD



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Cognitive Brain Development Laboratory

- Marijuana Use and Schizophrenia

- Brain Development in Adolescents with Genetics Risk Factors for Alcoholism

-The effects of binge drinking in College students on brain structure and function
Krystal Parker, PhD

Parker Lab

-Cerebellar contribution to cognition 

-Potential for cerebellar stimulation to rescue cognitive impairments in humans with schizophrenia

Jane Paulsen, PhD

University of Iowa Huntington's Disease Society of America Center of Excellence

-PREDICT-HD

- Neurobiological Predictors of Huntington's Disease (Predict-HD)

- Validation of the HD-Quality of Life Measure

- Functional Connectivity in Premanifest Huntington's Disease

Robert Philibert, MD, PhD - The Effects of Smoking on DNA Methylation in Primary Human Lymphocyte

- Examination of Genetic and GxE Effects in the Family and Community Health Studies

- Factors Influencing the Health Behaviors of Young African American Adults

- Using DNA Methylation to Determine Recent Alcohol Consumption Patterns

- A Transdiciplinary Center Focused on Rural African American Families
Andrew Pieper, MD, PhD Molecular Psychiatry Division

Andrew Pieper Laboratory

- Discovery, Characterization and Preclinical Development of Proneurogenic Drugs

- Pharmacologic Agents for Treatment of Anxiety in Autism
Kanchna Ramchandran, PhD



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- Dimensional Approach Toward Characterizing Positive Valence Systems in Psychosis

- Medication effects on schizophrenia
Gen Shinozaki, MD, FAPM Molecular Psychiatry Division

Gen Shinozaki Laboratory
Megan M Smith, PhD - Cognition and Psychoneuroimmunology in Multiple Sclerosis
Hanna E. Stevens, MD, PhD Molecular Psychiatry Division

 Psychiatry and Early Neurobiological Development Laboratory
Scott Stuart, MD Interpersonal Psychotherapy Institute

- Placebo-controlled Trial of Sertraline and IPT for Postpartum Depression

- Optimizing Fidelity of Interpersonal Psychotherapy for Depression

- Web-based Cognitive Behavioral Intervention
Beth Troutman, PhD Parent-Child Interaction Therapy  
Jatin Vaidya, PhD Cognitive Brain Development Laboratory

- Attentional Capacity in Adolescence
Carolyn Turvey, PhD - Combined Illness Management and Psychotherapy in Treating Depressed Elders

- My HealtheVet Project: Blue Button Feature Evaluation

- DRI Training: the Conduct of Psychosocial Care Intervention
Thomas Wassink, MD Molecular Psychiatry Division

Thomas Wassink Laboratory

- A Family-Genetic Study of Language in Autism
John Wemmie, MD, PhD Molecular Psychiatry Division

John Wemmie Laboratory

- Brain pH and Acid Sensing in Depression Related Behavior

- Modeling CO2‐Evoked Fear in Mice: Role of Acid‐Sensing Ion Channels

- Regulation of Cerebral Blood Flow by Acid-Sensing Ion Channels (ASICs)

- Anti-depressant Effects of Targeting ASIC1a in the Nucleus Accumbens
Virginia Willour, PhD



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- Attempted Suicide Candidate Gene Resequencing

- Suicide Epigenetics

- Genetic Risk Factor for Suicidal Behavior