Research by Investigator

Daniel O'Leary

List organized by investigator's last name
 A-B-C : D-E-F : G-H-I : J-K-L : M-N-O : P-Q-R : S-T-U : V-W-X-Y-Z

Investigator Initiative
Nancy Andreasen, MD, PhD - Brain Imaging in Major Psychoses: Examining Structural and Functional Connectivity
- MOSAIC: The Management of Schizophrenia In Clinical Practice
- Research Training in the Major Psychoses and Clinical Neurobiology
- Creativity, Schizophrenia, and Mood Disorders: Interrelationships and Neural Mechanisms
- Identifying the Brain Mechanisms Underlying Paranoia
- Relapse Prevention and Progressive Brain Change in Schizophrenia
- MOSAIC Site: The Management of Schizophrenia in Clinical Practice
Stephan Arndt, PhD Iowa Consortium for Substance Abuse Research and Evaluation
- Treatment Strategy for Alcohol Use Disorders in Veterans with Traumatic Brain Injury
Allan Andersen, MD -Risk factors for immune-related disease in individuals with substance use disorders
Leigh J Beglinger, PhD - Cognition in Clinical Trials for Huntington's Disease
Donald Black, MD - Treatment of Male and Female Incarcerated Offenders with Borderline Personality Disorder in the Iowa Prison System Using the STEPPS Program
William Coryell, MD - National Network of Depression Centers (NNDC): Common Assessment Program
- An Open-label, Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression 
- A Randomized, Double-blind, Multicenter, Active-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Subjects with Treatment-resistant Depression 
- A Prospective, Longitudinal, Observational Study to Evaluate Potential Predictors of Relapse in Subjects With Major Depressive Disorder Who Have Responded to Antidepressant Treatment
- Electronic Bridge to Mental Health (e-Bridge) for College Students
- Elucidating Inflammatory Markers of Suicidal Behavior in Depression and Bipolar Disorder 
- A Randomized, Multicenter, Crossover Study to Assess the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Subjects with Major Depressive Disorder 
Eric Epping, MD, PhD - Characterization of Schizophrenia Genetic Risk Factors from Whole Exome Sequencing
- Identification of DNA Sequence Mutations in Regions of Copy Number Variation in Schizophrenia Patients
- Creatine Safety, Tolerability, Efficacy in Huntington's Disease
Jess Fiedorowicz, MD, PhD Jess G. Fiedorowicz Laboratory
- Antipsychotics and Vascular Function in Bipolar Disorder
- Identifying Patients at Increased Risk of Heart Disease from Antipsychotic Medications
Michael Flaum, MD Iowa Consortium for Mental Health
Shizhong Han, PhD Molecular Psychiatry Division
Shizhong Han Laboratory
-Speeding Up Gene Discovery for Bipolar Disorder: in silico exome analysis and targeted sequencing (2013 NARSARD Young Investigator Grant)
- Enhancing Gene Discovery of Psychiatric Disorders Using Endophenotypes
- Integrated System Genetic Approaches for Psychiatric Disorders
- Using Prior Information to Boost the Power of Next-Generation Genetic Studies
- Linkage, Candidate Genes and Other Research Interests
Beng Choon Ho, MD - Adolescent Cannabis Use, Complex Brain Network Connectivity & Schizophrenia Risk
- High-throughput Combined Assay of Multiplex Serum Biomarkers for Schizophrenia
Karin Hoth, PhD

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Karin Hoth Lab

-Cardiopulmonary Mechanisms Affecting Cognition in COPD

Hans Johnson, PhD Brain Imaging Analysis: SINAPSE 
- National Alliance for Medical Image Computing (NAMIC)
- Track HD and Track-On HD
- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease
- 4D Shape Analysis for Modeling Spatiotemporal Change Trajectories in Huntington's Disease
Robin Kopelman, MD, MPH - Project LAUNCH
Samuel Kuperman, MD - Collaborative Study on the Genetics of Alcoholism (COGA)
- Collaborative Genomic Studies of Tourette Disorder
Doug Langbehn, MD, PhD - Track HD and Track-On HD
- Statistical Design of Huntington's Disease Studies and the Analysis and Modeling of HD Data
Jeffrey Long, PhD  - Functional Connectivity in Premanifest Huntington's Disease (co-investigator)
- Network of Excellence in Neuroscience Clinical Trials (NEXT)-DCC (co-investigator)
- Basal Ganglia Shape Analysis and Circuitry in Huntington's Disease (co-investigator)
- Neurobiological Predictors of Huntington's Disease (PREDICT-HD) (co-investigator)
Jacob Michaelson, PhD   Molecular Psychiatry Division
 Jacob Michaelson Laboratory
- Genetics of neurodevelopmental conditions (ASD, ID, DD)
- Gender differences in neurodevelopmental conditions
- Genetics of language ability
- Machine learning to improve the interpretation of non-coding genetic variants
- Functional and regulatory genomics in the brain
Del Miller, MD, PharmD - ACLAIMS (A Comparison of Long-Acting Injectiable Medications for Schizophrenia)
- Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Persistent, Predominant Negative Symptoms
- Phase III Study of an Adjunctive Medication for Patients with Schizophrenia with Sub-Optimally Controlled Symptoms
David Moser, PhD - Vascular Function, Cognition, and Brain MRI in Atherosclerotic Vascular Disease
Peg Nopoulos, MD Peg Nopoulos Laboratory
- Brain Structure, Function, and Growth in Children with Huntington's Disease
- Brain Structure and Function in Children at Risk for Huntington's Disease
- Brain Structure and Function in Children with Oral Clefts
Daniel O'Leary, PhD

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Cognitive Brain Development Laboratory
- Marijuana Use and Schizophrenia
- Brain Development in Adolescents with Genetics Risk Factors for Alcoholism
-The effects of binge drinking in College students on brain structure and function
Krystal Parker, PhD

Parker Lab

-Cerebellar contribution to cognition 

-Potential for cerebellar stimulation to rescue cognitive impairments in humans with schizophrenia

Jane Paulsen, PhD University of Iowa Huntington's Disease Society of America Center of Excellence
- Neurobiological Predictors of Huntington's Disease (Predict-HD)
- Validation of the HD-Quality of Life Measure
- Functional Connectivity in Premanifest Huntington's Disease
Robert Philibert, MD, PhD - The Effects of Smoking on DNA Methylation in Primary Human Lymphocyte
- Examination of Genetic and GxE Effects in the Family and Community Health Studies
- Factors Influencing the Health Behaviors of Young African American Adults
- Using DNA Methylation to Determine Recent Alcohol Consumption Patterns
- A Transdiciplinary Center Focused on Rural African American Families
Andrew Pieper, MD, PhD Molecular Psychiatry Division
Andrew Pieper Laboratory
- Discovery, Characterization and Preclinical Development of Proneurogenic Drugs
- Pharmacologic Agents for Treatment of Anxiety in Autism
Kanchna Ramchandran, PhD

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- Dimensional Approach Toward Characterizing Positive Valence Systems in Psychosis
- Medication effects on schizophrenia
Gen Shinozaki, MD, FAPM Molecular Psychiatry Division
Gen Shinozaki Laboratory
Megan M Smith, PhD - Cognition and Psychoneuroimmunology in Multiple Sclerosis
Hanna E. Stevens, MD, PhD Molecular Psychiatry Division
 Psychiatry and Early Neurobiological Development Laboratory
Scott Stuart, MD Interpersonal Psychotherapy Institute
- Placebo-controlled Trial of Sertraline and IPT for Postpartum Depression
- Optimizing Fidelity of Interpersonal Psychotherapy for Depression
- Web-based Cognitive Behavioral Intervention
Beth Troutman, PhD Parent-Child Interaction Therapy  
Jatin Vaidya, PhD Cognitive Brain Development Laboratory
- Attentional Capacity in Adolescence
Carolyn Turvey, PhD - Combined Illness Management and Psychotherapy in Treating Depressed Elders
- My HealtheVet Project: Blue Button Feature Evaluation
- DRI Training: the Conduct of Psychosocial Care Intervention
Thomas Wassink, MD Molecular Psychiatry Division
Thomas Wassink Laboratory
- A Family-Genetic Study of Language in Autism
John Wemmie, MD, PhD Molecular Psychiatry Division
John Wemmie Laboratory
- Brain pH and Acid Sensing in Depression Related Behavior
- Modeling CO2‐Evoked Fear in Mice: Role of Acid‐Sensing Ion Channels
- Regulation of Cerebral Blood Flow by Acid-Sensing Ion Channels (ASICs)
- Anti-depressant Effects of Targeting ASIC1a in the Nucleus Accumbens
Virginia Willour, PhD

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- Attempted Suicide Candidate Gene Resequencing
- Suicide Epigenetics
- Genetic Risk Factor for Suicidal Behavior