Daniel E. Hyer, PhD

Portrait
MR-Linac Technical Director
Medical Physics Residency Director
Associate Professor of Radiation Oncology

Contact Information

Primary Office
01615 Pomerantz Family Pavilion
200 Hawkins Drive
Iowa City, IA 52242
319-356-2441

Education

BS, Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA
MS, Medical Physics, Georgia Institute of Technology, Atlanta, GA
PhD, Medical Physics, University of Florida, Gainesville, FL
Resident, Medical Physics, University of Iowa

Licensure and Certifications

Therapeutic Medical Physics - American Board of Radiology
Radiation Therapy Physicist - Iowa Department of Public Health

Publications

Graves, S. A., Flynn, R. T. & Hyer, D. E. (2019). Dose point kernels for 2,174 radionuclides. Med Phys, 46(11), 5284-5293. PMID: 31461537.

Smith, B. R., Hyer, D. E., Flynn, R. T., Hill, P. & Culberson, W. (2019). Trimmer sequencing time minimization during dynamically collimated proton therapy using a colony of cooperating agents. Phys Med Biol, 64(20), 205025. PMID: 31484170.

Graves, S. A., Snyder, J., Boczkowski, A., St-Aubin, J., Wang, D., Yaddanapudi, S. & Hyer, D. E. (2019). Commissioning and performance evaluation of RadCalc for the Elekta Unity MRI-Linac. J Appl Clin Med Phys. PMID: 31722133.

Nowak, S., Hyer, D. E., Yang, R. & St-Aubin, J. (2019). Developing a source model for the Elekta Unity MR-Linac using a Grid-Based Boltzmann Solver. (Vols. 46). (6), pp. e159. Med Phys. DOI: 10.1002/mp.13589.

Graves, S., Hyer, D. E., Flynn, R. & Sunderland, J. (2019). A method for on-the-fly resampling of radionuclide energy deposition kernels for convolution-based voxelwise dosimetry. (Vols. 46). (6), pp. e115. Med Phys. DOI: 10.1002/mp.13589.

Boczkowski, A., Graves, S., Poplawski, L. & Hyer, D. E. (2019). Variability of Gamma Knife output calibration based on chamber type, phantom material, and dosimetry protocol. (Vols. 46). (6), pp. e117. Med Phys. DOI: 10.1002/mp.13589.

Geoghegan, T., Gutierrez, A., Flynn, R., Wang, D. & Hyer, D. E. (2019). Determining optimal collimator and range shifter sequence for a proton Dynamic Collimation System. (Vols. 46). (6), pp. e599. Med Phys. DOI: 10.1002/mp.13589.

Geoghegan, T., Smith, B., Gutierrez, A., Flynn, R., Wang, D. & Hyer, D. E. (2019). Investigating the impact of an unfocused collimator in pencil beam scanning proton therapy. (Vols. 46). (6), pp. e424. Med Phys. DOI: 10.1002/mp.13589.

Patwardhan, K., Geoghegan, T., Flynn, R., Wang, D. & Hyer, D. E. (2019). Dynamic Collimation System controller for pencil beam scanning proton therapy. (Vols. 46). (6), pp. e97. Med Phys. DOI: 10.1002/mp.13589.

Smith, B., Hyer, D. E., Flynn, R., Hill, P. & Culberson, W. (2019). Treatment time cutter ants: A novel swarm-intelligence approach to reduce trimmer sequencing times. (Vols. 46). (6), pp. e292. Med Phys. DOI: 10.1002/mp.13589.

Bennett, L., Smith, B., Flynn, R., Hyer, D. E. & Wang, D. (2019). Feasibility of pencil beam scanning proton therapy treatment planning with a Dynamic Collimation System in an FDA-cleared TPS. (Vols. 46). (6), pp. e101. Med Phys. DOI: 10.1002/mp.13589.

Graves, S., Tiwari, A., Hyer, D. E., Flynn, R., Buatti, J. M. & Sunderland, J. (2019). Impact of kernel truncation on 177Lu-DOTATATE and 131I-MIBG voxelwise dosimetry. (Vols. 46). (6), pp. e316. Med Phys. DOI: 10.1002/mp.13589.

Buatti, J., Buatti, J. M., Yaddanapudi, S., Pennington, E., Wang, D., Gross, B., St-Aubin, J., Hyer, D. E. & Flynn, R. (2019). Stereotactic radiotherapy of meningiomas and tumor beds with Gamma Knife Icon versus Volumetric Modulated Arc Therapy. (Vols. 46). (6), pp. e661. Med Phys. DOI: 10.1002/mp.13589.

Bennett, L., Smith, B., Wang, D., Flynn, R. & Hyer, D. E. (2019). Validation of a Pencil Beam Model for collimated proton therapy dose calculations. (Vols. 46). (6), pp. e167. Med Phys. DOI: 10.1002/mp.13589.

Buatti, J., Graves, S., Hyer, D. E., Pennington, E., Buatti, J. M. & Flynn, R. (2019). Extracranial dose delivered from frameless stereotactic radiosurgery with the Gamma Knife Icon. (Vols. 46). (6), pp. e646. Med Phys. DOI: 10.1002/mp.13589.

Smith, B., Hyer, D. E., Flynn, R. & Culberson, W. (2019). Technical Note: Optimization of Spot and Trimmer Position during Dynamically Collimated Proton Therapy. Med Phys, 46(4), 1922-1930. PMID: 30740709.

Smith, B., Pankuch, M., Hammer, C., Hyer, D. E., DeWerd, L. & Culberson, W. (In Press). Developing film dosimetry to benchmark dose distributions in dynamically collimated pencil beam scanning proton therapy. International Journal of Particle Therapy.

Smith, B., Hyer, D. E., Flynn, R. & Culberson, W. (In Press). Optimizing spot and trimmer positioning for a Dynamic Collimation System. International Journal of Particle Therapy.

Smith, B., Hyer, D. E., Hill, P. & Culberson, W. (2019). Secondary neutron dose from a Dynamic Collimation System during intracranial pencil beam scanning proton therapy: A Monte Carlo investigation. Int J Radiat Oncol Biol Phys, 103(1), 241-250. PMID: 30114462.

Snyder, J., Hyer, D. E., Flynn, R. T., Boczkowski, A. & Wang, D. (2018). The Commissioning and Validation of MONACO Treatment Planning System on an Elekta VersaHD Linear Accelerator. J Appl Clin Med Phys, 20(1), 184-193. PMID: 30525308.

Smith, B., Hyer, D. E., Hill, P. & Culberson, W. (2018). Monte Carlo methods to simulate secondary neutron dose for dynamically collimated SFUD and IMPT treatments using a Dynamic Collimation System. (Vols. 45). (6), pp. e642. Med Phys. DOI: 10.1002/mp.12938.

Smith, B., Hyer, D. E., Hill, P. & Culberson, W. (2018). A preliminary treatment planning sensitivity study for dynamically collimated pencil-beam scanning proton therapy treatments delivered with a Dynamic Collimation System. (Vols. 45). (6), pp. e488. Med Phys. DOI: 10.1002/mp.12938.

Graves, S., Hyer, D. E. (2018). Reversing the bias against diodes: Instantaneous dose rate corrections to improve scanning performance. (Vols. 45). (6), pp. e351. Med Phys. DOI: 10.1002/mp.12938.

Graves, S., Hyer, D. E., Flynn, R. & Bednarz, B. (2018). Dose kernels in water for more than 700 radioisotopes. (Vols. 45). (6), pp. e512. Med Phys. DOI: 10.1002/mp.12938.

Snyder, J., Hyer, D. E., Flynn, R. & Wang, D. (2018). Validating Monaco beam models for a Versa HD linac. (Vols. 45). (6), pp. e294. Med Phys. DOI: 10.1002/mp.12938.

Snyder, J., Flynn, R. T. & Hyer, D. E. (2017). Implementation of respiratory-gated VMAT on a Versa HD linear accelerator. J Appl Clin Med Phys, 18(5). PMID: 28834109.

Lawless, M., Seuntjens, J., Hyer, D. E., Giger, M., Svatos, M., Morales, M. & Viscariello, N. (2017). Annual Student Meeting: Provocative questions in medical physics training. (Vols. 44). (6), pp. 2721. Med Phys. DOI: 10.1002/mp.12304.

Snyder, J., Flynn, R. T. & Hyer, D. E. (2017). Dosimetric evaluation of respiratory-gated VMAT on a Versa HD linear accelerator. (Vols. 44). (6), pp. 2896. Med Phys. DOI: 10.1002/mp.12304.

Poplawski, L., Hyer, D. E. (2017). Quality assurance baselines for the integrated imaging systems on an Elekta Versa HD. (Vols. 44). (6), pp. 3124. Med Phys. DOI: 10.1002/mp.12304.

Hyer, D. E. (2017). Preparation strategies for ABR Therapy Part I and II. (Vols. 44). (6), pp. 3166. Med Phys. DOI: 10.1002/mp.12304.

Smith, B. R., Gelover, E., Moignier, A., Wang, D., Flynn, R. T., Lin, L., Kirk, M. L., Solberg, T. D. & Hyer, D. E. (2016). Technical Note: A treatment plan comparison between dynamic collimation and a fixed aperture during spot scanning proton therapy for brain treatment. (Vols. 43). (8), pp. 4693-4699. Med Phys. PMID: 27487886.

Hancock, S., Clements, C., Hyer, D. E., Nixon, E., Martin, E., Wang, B., Jani, S. & Gossman, M. (2016). Comprehensive machine isocenter evaluation with separation of gantry, collimator, and table variables. (Vols. 43). (6), pp. 3663. Med Phys. DOI: 10.1118/1.4957039.

Dalhart, A., Hyer, D. E., Allen, B., Flynn, R. T. & Johnston, H. (2016). SBRT lung: Moving beyond the 3D conformal paradigm with an Elekta VersaHD accelerator. (Vols. 43). (6), pp. 3612. Med Phys. DOI: 10.1118/1.4956831.

Gelover, E., Dalhart, A. & Hyer, D. E. (2016). The impact of modeling the treatment couch on patient specific VMAT QA. (Vols. 43). (6), pp. 3531. Med Phys. DOI: 10.1118/1.4956483.

Hyer, D. E., Fisher, R. F. & Guillemette, M. (2016). Applications in Radiology. In S. Beddar , L. Beaulieu (Eds.) Scintillation Dosimetry. Boca Raton, FL: CRC Press.

Moignier, A., Gelover, E., Wang, D., Smith, B., Flynn, R. T., Kirk, M. L., Lin, L., Solberg, T. D., Lin, A. & Hyer, D. E. (2016). Improving head and neck cancer treatments using dynamic collimation in spot scanning proton therapy. (Vols. 2). (4), pp. 544-554. Int Journal of Particle Therapy. DOI: 10.14338/IJPT-15-00026.1.

Moignier, A., Gelover, E., Smith, B. R., Wang, D., Flynn, R. T., Kirk, M. L., Lin, L., Solberg, T. D., Lin, A. & Hyer, D. E. (2016). Toward improved target conformity for two spot scanning proton therapy delivery systems using dynamic collimation. (Vols. 43). (3), pp. 1421-1427. Med Phys. PMID: 26936726.

Hyer, D. E., Wang, D., Moignier, A., Gelover, E., Lin, L., Kirk, M. L., Solberg, T. D. & Flynn, R. T. (2015). A dynamic collimation system for spot scanning proton therapy: Design and potential benefits for brain treatments. (Vols. 93). (3), pp. E574-E575. Int J Radiat Oncol Biol Phys. DOI: 10.1016/j.ijrobp.2015.07.2016.

Moignier, A., Gelover, E., Wang, D., Flynn, R. T., Kirk, M. L., Lin, L., Solberg, T. D., Lin, A. & Hyer, D. E. (2015). Benefits of collimation in head and neck cancers treated with spot scanning proton therapy. (Vols. 93). (3), pp. E580. Int J Radiat Oncol Biol Phys. DOI: 10.1016/j.ijrobp.2015.07.2029.

Moignier, A., Gelover, E., Wang, D., Smith, B., Flynn, R. T., Kirk, M. L., Lin, L., Solberg, T. D., Lin, A. & Hyer, D. E. (2015). Theoretical benefits of dynamic collimation in pencil beam scanning proton therapy for brain tumors: Dosimetric and radiobiological metrics. Int J Radiat Oncol Biol Phys. PMID: 26614424.

Hyer, D. E., Bova, F. J. & Buatti, J. M. (2015). Radiosurgical Devices. In L. D. Lunsford , J. P. Sheehan (Eds.) Intracranial Stereotactic Radiosurgery, 2nd Edition. New York, NY: Thieme Medical Publishers, Inc..

Hancock, S., Hyer, D. E. & Nixon, E. (2015). A new method for optimizing radiation isocenter for linac-based SRS. (Vols. 42). (6), pp. 3343. Med Phys. DOI: 10.1118/1.4924415.

Smith, B., Gelover, E., Wang, D., Moignier, A., Flynn, R. T., Lin, L., Kirk, M., Solberg, T. & Hyer, D. E. (2015). Collimation methods in spot scanning proton therapy: A treatment plan comparison between a fixed aperture and a dynamic collimation system. (Vols. 42). (6), pp. 3374. Med Phys. DOI: 10.1118/1.4924548.

Moignier, A., Gelover, E., Wang, D., Flynn, R. T., Kirk, M., Lin, L., Solberg, T., Lin, A. & Hyer, D. E. (2015). Therapeutic benefits of collimation in spot scanning proton therapy in the treatment of brain cancer. (Vols. 42). (6), pp. 3617. Med Phys. DOI: 10.1118/1.4925666.

Gelover, E., Smith, B., Wang, D., Hill, P. M., Flynn, R. T. & Hyer, D. E. (2015). Calculation of asymmetric beamlets to account for collimation in spot scanning proton therapy. (Vols. 2). (1), pp. 234-235. International Journal of Particle Therapy. DOI: 10.14338/IJPT.15-PTCOG-NA.1.

Gelover, E., Moignier, A., Smith, B., Wang, D., Flynn, R., Lin, L., Kirk, M., Solberg, T. & Hyer, D. (2015). Combining collimation with spot-scanning proton therapy to improve brain treatments. (Vols. 16). (3), pp. 444. J Appl Clin Med Phys.

Hyer, D. E., Wang, D., Hill, P. M. & Flynn, R. T. (2015). Improving spot scanning proton therapy with collimation. (Vols. 2). (1), pp. 153-154. International Journal of Particle Therapy. DOI: 10.14338/IJPT.15-PTCOG-NA.1.

Morel, P., Wu, X., Blin, G., Vialette, S., Flynn, R., Hyer, D. & Wang, D. (2015). Spot weight adaptation for moving target in spot scanning proton therapy. Frontiers in Oncology, 5(119), 1-7. PMID: 26075184.

Wang, D., Smith, B. R., Gelover, E., Flynn, R. T. & Hyer, D. E. (2015). A method to select aperture margin in collimated spot scanning proton therapy. Phys Med Biol, 60(7), N109-N119. PMID: 25776926.

Gelover, E., Wang, D., Hill, P. M., Flynn, R. T., Gao, M., Laub, S., Pankuch, M. & Hyer, D. E. (2015). A method for modeling laterally asymmetric proton beamlets resulting from collimation. Med Phys, 42(3), 1321-1334. PMID: 25735287.

Hoerner, M. R., Stepusin, E. J., Hyer, D. E. & Hintenlang, D. E. (2015). Characterizing energy dependence and count rate performance of a dual scintillator fiber-optic detector for computed tomography. Med Phys, 42(3), 1268-1279. PMID: 25735282.

Wang, D., Dirksen, B., Hyer, D. E., Buatti, J. M., Sheybani, A., Dinges, E., Feldeman, N., TenNapel, M., Bayouth, J. E. & Flynn, R. T. (2014). Impact of spot size on plan quality of spot scanning proton radiosurgery for peripheral brain lesions. Med Phys, 41(12), 121705. PMID: 25471952.

Hyer, D. E., Hill, P. M., Wang, D., Smith, B. R. & Flynn, R. T. (2014). Effects of spot size and spot spacing on lateral penumbra reduction when using a dynamic collimation system for spot scanning proton therapy. Phys Med Biol, 59(22), N187-196. PMID: 25330783.

Hyer, D. E., Hill, P. M., Wang, D., Smith, B. R. & Flynn, R. T. (2014). A dynamic collimation system for penumbra reduction in spot-scanning proton therapy: proof of concept. Med Phys, 41(9), 091701. PMID: 25186376.

Sheybani, A., TenNapel, M. J., Lack, W. D., Clerkin, P., Hyer, D. E., Sun, W. & Jacobson, G. M. (2014). Risk of radiation-induced malignancy with heterotopic ossification prophylaxis: a case-control analysis. Int J Radiat Oncol Biol Phys, 89(3), 584-589. PMID: 24803038.

Hyer, D. E., Hill, P. M., Wang, D., Smith, B. R. & Flynn, R. T. (2014). A dynamic collimation system for spot scanning proton therapy: Conceptual overview. (Vols. 41). (6), pp. 496. Med Phys. DOI: 10.1118/1.4889404.

Gelover, E., Wang, D., Hill, P. M., Flynn, R. T. & Hyer, D. E. (2014). Analytical modeling and dose calculation method for asymmetric proton pencil beams. (Vols. 41). (6), pp. 550. Med Phys. DOI: 10.1118/1.4889600.

Wang, D., Smith, B. R., Hill, P. M., Gelover, E., Flynn, R. T. & Hyer, D. E. (2014). Determining the optimal collimator position for collimated pencil beam scanning proton therapy. (Vols. 41). (6), pp. 550-51. Med Phys. DOI: 10.1118/1.4889601.

Hill, P. M., Wang, D., Flynn, R. T. & Hyer, D. E. (2014). The effects of a dynamic collimation system on proton pencil beams to improve lateral tissue sparing in spot scanned proton therapy. (Vols. 41). (6), pp. 298. Med Phys. DOI: 10.1118/1.4888654.

Sheybani, A., Ahmed, R., TenNapel, M., Pennington, E., Hyer, D. E., Anderson, K., Menezes, A., Hitchon, P. & Buatti, J. (2014). Preliminary experience in treating skull base chordomas with high-dose hyperfractionated stereotactic photon radiation therapy. J Radiat Oncol, 3(1), 57-64. DOI: 10.1007/s13566-013-0122-7.

Sheybani, A., TenNapel, M. J., Lack, W. D., Hyer, D. E. & Jacobson, G. M. (2013). The risk of radiation-induced malignancy with heterotopic ossification prophylaxis: A case-control analysis. In Proceedings of the ASTRO 55th Annual Meeting. (Vols. 87). (2), pp. S561. Int J Radiat Oncol Biol Phys. DOI: 10.1016/j.ijrobp.2013.06.1487.

Dirksen, B., Wang, D., Hyer, D. E., Buatti, J. M., Sheybani, A., TenNapel, M., Bayouth, J. & Flynn, R. (2013). Radiosurgery of peripheral brain lesions by spot scanning proton therapy. (Vols. 40). (6), pp. 364. Med Phys. DOI: 10.1118/1.4815117.

Hyer, D. E., Mart, C. J. & Nixon, E. (2012). Development and implementation of an EPID-based method for localizing isocenter. J Appl Clin Med Phys, 13(6), 72-81. PMID: 23149787.

Sheybani, A., Ahmed, R., TenNapel, M. J., Hyer, D. E., Anderson, K. & Buatti, J. M. (2012). High-dose hyperfractionated stereotactic photon radiation therapy for skull based chordomas. In Proceedings of the ASTRO 54th Annual Meeting. (Vols. 84). (3), pp. S288-S289. Int J Radiat Oncol Biol Phys. DOI: 10.1016/j.ijrobp.2012.07.753.

Hyer, D. E., Sheybani, A., Jacobson, G. M. & Kim, Y. (2012). The dosimetric impact of heterogeneity corrections in high-dose-rate ¹?²Ir brachytherapy for cervical cancer: Investigation of both conventional Point-A and volume-optimized plans. Brachytherapy, 11(6), 515-520. PMID: 22386723.

Hyer, D. E., Mart, C. J. (2012). Development and implementation of an automated algorithm to determine radiation isocenter, radiation vs. light field coincidence, and analyze strip tests. (Vols. 39). (6), pp. 3707. Med Phys. DOI: 10.1118/1.4735079.

Hyer, D. E., Sheybani, A., Jacobson, G. & Kim, Y. (2011). The impact of heterogeneity corrections in high dose rate brachytherapy. (Vols. 38). (6), pp. 3573. Med Phys. DOI: 10.1118/1.3612329.

Hyer, D. E., Hintenlang, D. E. (2010). Estimation of organ doses from kilovoltage cone-beam CT imaging used during radiotherapy patient position verification. Med Phys, 37(9), 4620-4626. PMID: 20964180.

Hyer, D. E., Hintenlang, D. E. (2010). Estimation of organ doses from kV-CBCT imaging systems used in radiation therapy. (Vols. 37). (6), pp. 3103. Med Phys. DOI: 10.1118/1.3468043.

Hyer, D. E., Serago, C. F., Kim, S., Li, J. G. & Hintenlang, D. E. (2010). An organ and effective dose study of XVI and OBI cone-beam CT systems. J Appl Clin Med Phys, 11(2), 181-197. PMID: 20592702.

Winslow, J. F., Hyer, D. E., Fisher, R. F., Tien, C. J. & Hintenlang, D. E. (2009). Construction of anthropomorphic phantoms for use in dosimetry studies. J Appl Clin Med Phys, 10(3), 195-204. PMID: 19692982.

Hyer, D. E., Hintenlang, D. E. (2009). Organ doses from cone-beam CT in radiation therapy. (Vols. 36). (6), pp. 2437. Med Phys. DOI: 10.1118/1.3181132.

Hyer, D. E., Fisher, R. F. & Hintenlang, D. E. (2009). Characterization of a water-equivalent fiber-optic coupled dosimeter for use in diagnostic radiology. Med Phys, 36(5), 1711-1716. PMID: 19544788.