Mark Smith, MD

Portrait
Clinical Director, Department of Radiation Oncology
Clinical Associate Professor of Radiation Oncology

Education

BS, Physics, Iowa State University
Biomedical Engineering, University of Iowa
Computer Science, University of Iowa
MD, Medicine, University of Iowa
MA, Medical Education, University of Iowa
Resident, Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI

Licensure and Certifications

American Board of Radiology (Radiation Oncology)
Iowa Medical License

Publications

Duncan, C. E., Olson, A. K. & Smith, M. (2009). Ultrasound versus cone beam CT for prostate localization in external beam radiotherapy: No evidence of early biochemical failure. ARS Annual Meeting.

Bodeker, K. L., Allen, B. G., Smith, M. C., Monga, V., Sandhu, S., Hohl, R. J., Carlisle, T. L., Brown, H. A., Hollenbeck, N. J., Vollstedt, S., Greenlee JDW,, Howard, M. A., Mapuskar, K. A., Seyedin, S. N., Caster, J. M., Jones, K. A., Cullen, J. J., Berg, D. J., Wagner, B. A., Buettner, G. R., TenNapel, M. J., Smith, B. J., Spitz, D. R. & Buatti, J. M. (2019). First-in-human phase 1 clinical trial of pharmacological ascorbate combined with radiation and temozolomide for newly diagnosed glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. PMID: 31427282.

Seyedin, S. N., Mitchell, D. L., Mott, S. L., Russo, J. K., Tracy, C. R., Snow, A. N., Parkhurst, J. R., Smith, M. C., Buatti, J. M. & Watkins, J. M. (2019). Is More Always Better? An Assessment of the Impact of Lymph Node Yield on Outcome for Clinically Localized Prostate Cancer with Low/Intermediate Risk Pathology (pT2-3a/pN0) Managed with Prostatectomy Alone. Pathology oncology research : POR, 25(1), 209-215. PMID: 29079967.

Guram, K., Smith, M., Ginader, T., Bodeker, K., Pelland, D., Pennington, E., Buatti, J. (Eds.) (In Press). Using Smaller than Standard Radiation Treatment Margins Does Not Change Survival Outcomes in High-grade Gliomas. Practical Radiation Oncology.

Welsh, J. L., Jaber, O., Ivanovic, M., Johlin, F. C., El Abiad, R. G., Clamon, G. H., Smith, M. C. & Chan CHF, (2018). Rapidly Progressing Primary Extrahepatic Bile Duct Signet-Ring Cell Carcinoma in a Caucasian Woman. Journal of gastrointestinal cancer, 49(1), 63-66. PMID: 27270710.

Mohiuddin, I. H., Furqan, M., Clamon, G., Keech, J., Anderson, C., Smith, M. C., Buatti, J. M. & Allen, B. G. (2017). A Single-Institution Analysis of Thymic Carcinoma Treatedwith Multi-Modality Therapy. Annals of Radiation Therapy and Oncology, 1(3), Article 1011. PMID: 30148284.

Seyedin, S. N., Mitchell, D. L., Russo, J. K., Mott, S. L., Snow, A. N., Tracy, C. R., Parkhurst, J. R., Smith, M. C., Buatti, J. M. & Watkins, J. M. (2017). Is more always better? An assessment of the clinical impact of nodal yield for clinically localized prostate cancer with low/intermediate risk pathology (pT2-3a/pN0) managed with prostatectomy alone. Pathol Oncol Res. PMID: 29079967.

Schoenfeld, J. D., Sibenaller, Z. A., Cramer-Morales, K. L., Mapuskar, K. A., Wagner, B. A., Furqan, M., Sandhu, S., Carlisle, T. L., Smith, M. C., AbuHejleh, T., Berg, D. J., Zhang, J., Keech, J., Parekh, K. R., Bhatia, S., Monga, V., Bodeker, K. L., Ahmann, L., Vollstedt, S., Brown, H., Shanhan Kauffman, E. P., Schall, M. E., Hohl, R. J., Clamon, G. H., Greenlee, J. D., Howard, M. A., Schultz, M. K., Smith, B. J., Riley, D. P., Domann, F. E., Cullen, J. J., Buettner, G. R., Buatti, J. M., Spitz, D. & Allen, B. G. (2017). O2*- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell, 268. PMID: 28810149.

Schoenfeld, J. D., Sibenaller, Z. A., Mapuskar, K. A., Wagner, B. A., Cramer-Morales, K. L., Furqan, M., Sandhu, S., Carlisle, T. L., Smith, M. C., Abu Hejleh, T., Berg, D. J., Zhang, J., Keech, J., Parekh, K. R., Bhatia, S., Monga, V., Bodeker, K. L., Ahmann, L., Vollstedt, S., Brown, H., Kauffman EPS,, Schall, M. E., Hohl, R. J., Clamon, G. H., Greenlee, J. D., Howard, M. A., Schultz, M. K., Smith, B. J., Riley, D. P., Domann, F. E., Cullen, J. J., Buettner, G. R., Buatti, J. M., Spitz, D. R. & Allen, B. G. (2017). O2·- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer cell, 32(2), 268. PMID: 28810149.

Plichta, K., Camden, N., Furqan, M., Abu Hejleh, T., Clamon, G. H., Zhang, J., Flynn, R. T., Bhatia, S. K., Smith, M. C., Buatti, J. M. & Allen, B. G. (2017). SBRT to Adrenal Metastases Provides High Local Control with Minimal Toxicity Advances in Radiation Oncology. Advances in Radiation Oncology, 2(4), 581-587. PMID: 29204525.

Plichta, K., Camden, N., Furqan, M., Hejleh, T. A., Clamon, G. H., Zhang, J., Flynn, R. T., Bhatia, S. K., Smith, M. C., Buatti, J. M. & Allen, B. G. (2017). SBRT to adrenal metastases provides high local control with minimal toxicity. Advances in radiation oncology, 2(4), 581-587. PMID: 29204525.

Smith, M. C., Russo, J. K., Trac y, C., Mitchell, D., Mott, S., Buatti, J. M. & Watkins, J. M. (2017). Gleason <(G6) Prostate Cancer (PC) at Radical Prostatectomy (RP): Does a High-Risk Setting Truly Exist? A Recursive Partitioning Analysis (RPA). (Vols. 15). (2), pp. 242-247. 2016 Genitourinary Cancers Symposium January 7-9, 2016. PMID: 27338519.

Hitchon, P. W., Holland, M., Noeller, J., Smith, M. C., Moritani, T., Jerath, N. & He, W. (2016). Options in treating trigeminal neuralgia: Experience with 195 patients. Clin Neurol Neurosurg, 149, 166-170. PMID: 27556293.

Smith, B., Gelover, E., Moignier, A., Wang, D., Flynn, R. T., Lin, L., Kirk, M., Solbert, T. & Hyer, D. E. (2016). Technical Note: A treatment plan comparison between dynamic collimation and a fixed aperture during spot scanning proton therapy for brain treatment. Med Phys, 43, 4693. PMID: 27487886.

Kaelberer, J. B., O'Donnell, M. A., Mitchell, D. L., Snow, A. N., Mott, S. L., Buatti, J. M., Smith, M. C. & Watkins, J. M. (2016). Incidental prostate cancer diagnosed at radical cystoprostatectomy forbladder cancer: disease-specific outcomes and survival. Prostate Int, 4, 107-112.

Welsh, J. L., Jaber, O., Ivanovic, M., Johlin, F. C., El Abiad, R. G., Clamon, G. H., Smith, M. C. & Chan, C. H. (2016). Rapidly Progressing Primary Extrahepatic Bile Duct Signet-Ring Cell Carcinoma in a Caucasian Women. J Gastrointest Cancer. PMID: 27270710.

Watkins, J. M., Mitchell, D. L., Russo, J. K., Mott, S. L., Tracy, C. R., Smith, M. C. & Buatti, J. M. (2016). Gleason Score = 6 Prostate Cancer at Radical Prostatectomy: Does a High-Risk Setting Truly Exist? A Recursive Partitioning Analysis. Clin Genitourin Cancer, S1558-7673. PMID: 27338519.

Mitchell, D. L., Tracy, C. R., Buatti, J. M., Smith, M. C., Snow, A. N., Henry, M. D., Tewfik, H. H. & Watkins, J. M. (2016). Individualization of adjuvant therapy following radical prostatectomy for clinically localized prostate cancer: current status and future directions. Clin Genitourin Cancer.

Mitchell, D. L., Tracy, C. R., Buatti, J. M., Smith, M. C., Snow, A. N., Henry, M. D., Vaena, D. A., Tewfik, H. H. & Watkins, J. M. (2016). Individualization of Adjuvant Therapy After Radical Prostatectomy for Clinically Localized Prostate Cancer: Current Status and Future Directions. Clinical genitourinary cancer, 14(1), 12-21. PMID: 26341039.

Muruganandham, M., Clerkin, P. P., Smith, B. J., Anderson, C. M., Morris, A., Capizzano, A. A., Magnotta, V., McGuire, S. M., Smith, M. C., Bayouth, J. E. & Buatti, J. M. (2014). 3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessmetn of glioblastoma patients during external beam radiation therapy. Int J Radiat Oncol Biol Phys, 90(1), 181-9. PMID: 24986746.

Hoover, A. C., Anderson, C. M., Hoffman, H. T., de Magalhaes Silverman, M., Syurbu, S. I. & Smith, M. C. (2014). Laryngeal Chloroma Heralding relapse of Acute Myeloid Leukemia. J Clin Oncol, 32(7), e18-21. PMID: 24419134.

Bockholt, N. A., DeRoo, E. M., Nepple, K. G., Modrick, J. M., Smith, M. C., Fallon, B., Hass, A. C., Tracy, C. R. & Brown, J. A. (2013). First 100 Cases at a Low Volume Prostate Brachytherapy Institute: Learning Curve and the Importance of Continuous Quality Improvement. Can J Urol, 20(5), 6907-12. PMID: 24128827.

Bockholt, N. A., DeRoo, E. M., Nepple, K. G., Modrick, J. M., Smith, M. C., Fallon, B., Hass, A. C., Tracy, C. R. & Brown, J. A. (2013). First 100 cases at a low volume prostate brachytherapy institution: learning curve and the importance of continuous quality improvement. The Canadian journal of urology, 20(5), 6907-12. PMID: 24128827.

Bylund, K. C., Bayouth, J., Smith, M., Hass, C., Bhatia, S. & Buatti, J. M. (2008). Analysis of interfraction prostate motion using megavoltage cone beam CT. Int J Radiat Oncol Biol Phys, 72(3), 949-56. PMID: 19014783.

Bylund, K. C., Bayouth, J., Smith, M., Siochi, R. & Buatti, J. M. (2008). Geometric and dosimetric impace of interfraction prostate motion measured with megavoltage cone beam CT. ASTRO Annual Meeting.

Muruganandham, M., Bayouth, J., Smith, M. & Buatti, J. M. (2008). Impact of 3-Tesla MR spectroscopic imaging in the delineation of high grade glioma target volumes for radiation therapy planning. ASTRO Annual Meeting.

Bylund, K. C., Bayouth, J., Smith, M. & Buatti, J. M. (2008). Analysis of interfraction prostate motion using megavoltage cone beam CT. ESTRO 27.

Buatti, J. M., Ryken, T. C., Smith, M., Sneed, P., Suh, J. H., Mehta, M. & Olson, J. J. (2008). Radiation Therapy of Pathologically Confirmed Newly Diagnosed Glioblastoma in Adults. J Neurooncol, 89(3), 313-37. PMID: 18712283.

Muruganandham, M., Bayouth, J., Kearney, W., Smith, M. & Buatti, J. M. (2008). Integration and verification of 3T magnetic resonance spectroscopic imaging in radiation therapy treatment planning. American Association of Physicists in Medicine National Meeting.

Bylund, K. C., Bhatia, S., Smith, M., Buechler-Price, J. L., Buatti, J. M., Bayouth, J. & Hass, A. C. (2008). Interobserver Variation in Megavoltage Cone Beam CT (MV CBCT) Based Corrections in Head and Neck Image Guided Radiotherapy. pp. 46. American Radium Society 2008 Annual Meeting Proceedings.

Olson, A. K., Smith, M., Ryken, T. C., Hitchon, P. W., Pennington, E. C., Smith, B. J., Bayouth, J. & Buatti, J. M. (2008). Frameless Stereotactic Radiosurgery for Treatment of Intracranial Metastases. Int J Radiat Oncol Biol Phys, 72(1), S203.

Bylund, K. C., Bayouth, J., Smith, M., Siochi, R. & Buatti, J. M. (2008). Geometric and Dosimetric Impact of Interfraction Prostate Motion Measured with Megavoltage Cone Beam CT. Int J Radiat Oncol Biol Phys, 72(1), S338.

Muruganandham, M., Bayouth, J., Smith, M. & Buatti, J. M. (2008). Impact of 3-Tesla MR Spectroscopic Imaging in the Delineation of High Grade Glioma Target Volumes for Radiation Therapy Planning. Int J Radiat Oncol Biol Phys, 72(1), S210.

Muruganandham, M., Bayouth, J., Kearney, W., Smith, M. & Buatti, J. M. (2008). Integration and Verification of 3T Magnetic Resonance Spectroscopic Imaging in Radiation Therapy Treatment Planning. Med Phys, 35, 2704.

Olson, A., Ryken, T., Smith, M., Bayouth, J., Pennington, E. C., Hitchon, P. W. & Buatti, J. M. (2008). Surgical Resection and Frameless Stereotactic Radiosurgery for Solitary Intracranial Metastatic Disease. Neuro-Oncology, 10(5), 912.

Smith, M. (2007). Image-guided stereotactic radiosurgery using a specially designed high-dose-rate linac. Med Dosim, 32(2), 134-41. PMID: 17472892.

Smith, M., Ryken, T. C. & Buatti, J. M. (2006). Radiotoxicity after Conformal Radiation Therapy for Benign Intracranial Tumors. Neurosurg Clin N Ame, 17(2), 169-80. PMID: 16793508.

Anderson, W. B., Lakes, R. S. & Smith, M. (1995). Holographic Evaluation of Warp in the Torsion of a Bar of Cellular Solid. Cellular Polymers, 14(1), 1-13.

Mitchell, D. L., Russo, J. K., Mott, S. L., Trac;y, C. R., Smith, M. C., Buatti, J. M. & Watkins, J. M. Can high-grade prostate cancer (Gleason 8-10) be cured with definitive local therapy without testosterone suppression? Disease control and survival outcomes after up-front radical prostatectomy in patients with high-grade clinically localized disease. Clinics Oncol – Radiat Oncol.

Watkins, J. M., Mitchell, D. L., Russo, J. K., Mott, S. L., Tracy, C. R., Smith, M. C. & Buatti, J. M. Gleason <6 prostate cancer at prostatectomy: does a high-risk setting truly exist? A recursive partitioning analysis.