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Mitchell C. Coleman, PhD

Assistant Professor of Radiation Oncology
Assistant Professor of Orthopedics and Rehabilitation

Contact Information

Primary Office
1182 Medical Laboratories (ML)
Iowa City, IA 52242


BSE, Biomedical Engineering, University of Iowa
BA, Religious Studies, University of Iowa
MA, Religious Studies, University of Iowa
PhD, Free Radical and Radiation Biology, University of Iowa
Postdoctoral Scholar, Orthopaedics, University of Iowa Carver College of Medicine

Education/Training Program Affiliations

Free Radical and Radiation Biology Graduate Program


Mapuskar, K. A., Wen, H., Holanda, D. G., Rastogi, P., Steinbach, E., Han, R., Coleman, M. C., Attanasio, M., Riley, D. P., Spitz, D. R., Allen, B. G. & Zepeda-Orozco, D. (2019). Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease. Redox Biology, 20, 98-106. PMID: 30296702.

Coleman, M. C., Brouillette, M. J., Andresen, N. S., Oberley-Deegan, R. E. & Martin, J. A. (2017). Differential Effects of Superoxide Dismutase Mimetics after Mechanical Overload of Articular Cartilage. Antioxidants (Basel Switzerland), 6(4). PMID: 29189731.

Coleman, M. C., Goetz, J. E., Brouillette, M. J., Seol, D., Willey, M. C., Petersen, E. B., Anderson, H. D., Hendrickson, N. R., Compton, J., Khorsand, B., Morris, A. S., Salem, A. K., Fredericks, D. C., McKinley, T. O. & Martin, J. A. (In Press). Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis. Science Translational Medicine, 10(427), pii: eaan5372. PMID: 29437147.

Goetz, J. E., Coleman, M. C., Fredericks, D. C., Petersen, E. B., Martin, J. A., McKinley, T. O. & Tochigi, Y. (2017). Time-dependent loss of mitochondrial function precedes progressive histologic cartilage degeneration in a rabbit meniscal destabilization model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 35(3), 590-9. PMID: 27279147.

Coleman, M. C., Ramakrishnan, P. S., Brouillette, M. J. & Martin, J. A. (2016). Injurious Loading of Articular Cartilage Compromises Chondrocyte Respiratory Function. Arthritis & rheumatology (Hoboken, N.J.), 68(3), 662-71. PMID: 26473613.

Coleman, M. C., Olivier, A. K., Jacobus, J. A., Mapuskar, K. A., Mao, G., Martin, S. M., Riley, D. P., Gius, D. & Spitz, D. R. (2014). Superoxide mediates acute liver injury in irradiated mice lacking sirtuin 3. Antioxidants & redox signaling, 20(9), 1423-35. PMID: 23919724.

Jacobus, J. A., Duda, C. G., Coleman, M. C., Martin, S. M., Mapuskar, K., Mao, G., Smith, B. J., Aykin-Burns, N., Guida, P., Gius, D., Domann, F. E., Knudson, C. M. & Spitz, D. R. (2013). Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender. Radiation research, 180(2), 156-65. PMID: 23819597.

Tao, R., Coleman, M. C., Pennington, J. D., Ozden, O., Park, S. H., Jiang, H., Kim, H. S., Flynn, C. R., Hill, S., Hayes McDonald, W., Olivier, A. K., Spitz, D. R. & Gius, D. (2010). Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Molecular cell, 40(6), 893-904. PMID: 21172655.

Coleman, M. C., Asbury, C. R., Daniels, D., Du, J., Aykin-Burns, N., Smith, B. J., Li, L., Spitz, D. R. & Cullen, J. J. (2008). 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free radical biology & medicine, 44(3), 322-31. PMID: 18215740.