Ryan Flynn, PhD

Portrait
Director of Medical Physics
Clinical Associate Professor of Radiation Oncology

Contact Information

Iowa City, IA 52242
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Primary Office: 01623 PFP-LLW
200 Hawkins Drive
Iowa City, IA 52242
+1319-384-8461

Education

BA, Physics and Mathematics, Luther College
MS, Medical Physics, University of Wisconsin-Madison
PhD, Medical Physics, University of Wisconsin-Madison

Licensure and Certifications

American Board of Radiology in Therapeutic Medical Physics - American Board of Radiology

Publications

Ding, G. X., Alaei, P., Curran, B., Flynn, R., Gossman, M., Mackie, T. R., Miften, M., Morin, R., Xu, X. G. & Zhu, T. C. (2018). Image Guidance Doses Delivered During Radiotherapy: Quantification, Management, and Reduction: Report of the AAPM Therapy Physics Committee Task Group 180. Med Phys. PMID: 29468678.

Ding, G. X., Alaei, P., Curran, B., Flynn, R., Gossman, M., Mackie, T. R., Miften, M., Morin, R., Xu, X. G. & Zhu, T. C. (2018). Image guidance doses delivered during radiotherapy: Quantification, management, and reduction: Report of the AAPM Therapy Physics Committee Task Group 180. (Vols. 45). (5), pp. e84-99. Med Phys. DOI: https://doi.org/10.1002/mp.12824.

Wears, B., Mohiuddin, I., Flynn, R., Kim, Y., Waldron, T., Allen, B. & Xia, J. (2017). Design of a compact collimator and 3D imaging system for a scanning beam low-energy intraoperative radiation therapy system for pancreatic cancer. IEEE Engineering in Medicine and Biology Society (EMBC).

Snyder, J., Flynn, R. & Hyer, D. (2017). Dosimetric Evaluation of Respiratory-Gated VMAT on a Versa HD Linear Accelerator. (Vols. 44). (6), pp. 2896. AAPM Annual Meeting - Medical Physics.

Cho, M., Wu, X., Dadkhah, H., Flynn, R., Kim, Y. & Xu, W. (2017). Fast computational Optimization Method for Rotating-Shield Brachytherapy Treatment Planning. (Vols. 44). (6), pp. 3088. APPM Annual Meeting - Medical Physics.

Snyder, J., Flynn, R. T. & Hyer, D. E. (2017). Implementation of Respiratory-Gated VMAT on a Versa HD Linear Accelerator. J Appl Clin Med Phys, 18(5), 152-161. PMID: 28834109.

Flynn, R., Kim, Y., Wu, X., Xu, W., Dadkhah, H., Cho, M. & Patwardhan, K. (2017). Multi-Catheter Rotating Shield Brachytherapy Control System. (Vols. 44). (6), pp. 3193. AAPM Annual Meeting -- Medical Physics.

Plichta, K., Camden, N., Furqan, M., Abu Heijleh, T., Clamon, G. H., Zhang, J., Flynn, R. T., Bhatia, S. K., Smith, M. C., Buatti, J. M. & Allen, B. G. (2017). SBRT to Adrenal Metastases Provides High Local Control with Minimal Toxicity Advances in Radiation Oncology. Advances in Radiation Oncology, 2(4), 581-587. PMID: 29204525.

Cho, M., Wu, X., Hossein, D., Jirong, Y., R, F. T., Y, K. & W, X. (2017). Fast Dose Optimization for Rotating Shield Brachytherapy. Med Phys, 44(10), 5384-5392. PMID: 28744870.

Mohiuddin, I., Imran, H., Flynn, R. T., Buatti, J. M. & Xia, J. (2017). Visualization Radiation Dosimetry in an Interactive Augmented Reality Environment for Intuitive Plan Evaluation. ASTRO-San Diego California.

Dadkhah, H., Hopfensperger, K. M., Kim, Y., Wu, X. & Flynn, R. T. (2017). Multisource Rotating Shield Brachytherapy Apparatus for Prostate Cancer. Int J Radiat Oncol Biol Phys, 99(3), 719-728. PMID: 28843372.

Kim, Y., Chesnut, D., Wagner, B. S., Oldham, A. J., Schmitt, B., Sangster, N., Jespersen, J. R., Burk, N., Wardenburg, M., Flynn, R. T., Sun, W., Papworth, D., From, R. P. & Buatti, J. (2017). Ferromagnetic Metal Side-Rails on Air-Hover HDR Patient Transport Table can cause Severe Skin Burns on Patients during MR simulation for Brachytherapy. (Vols. 99). (2), pp. E556-E557. ASTRO 2017--International Journal of Radiation Oncology*Biology*Physics.

Wears, B., Mohiuddin, I., Flynn, R., Kim, Y., Waldron, T., Allen, B. & Xia, J. (2017). Design of a compact collimator and 3D imaging system for a scanning beam low-energy intraoperative radiation therapy system for pancreatic cancer. pp. 4325-4328. IEEE EMBC Conference proceedings. PMID: 29060854.

Smith, B., Gelover, E., Moignier, A., Wang, D., Flynn, R. T., Lin, L., Kirk, M., Solberg, T. & Hyer, D. E. (2016). Technical Note: A treatment plan comparison between dynamic collimation and a fixed aperture during spot scanning proton therapy for brain treatment. Med Phys, 43(8), 4693. PMID: 27487886.

Moignier, A., Gelover, E., Wang, D., Smith, B., Flynn, R., Kirk, M., Lin, L., Solberg, T., Lin, A. & Hyer, D. (2016). Theoretical Benefits of Dynamic Collimation in Pencil Beam Scanning Proton Therapy for Brain Tumors: Dosimetric and Radiobiological Metrics. Int J Radiat Oncol Biol Phys, 95(1), 171-80. PMID: 26614424.

Moignier, A., Gelover, E., Smith, B. R., Wang, D., Flynn, R. T., Kirk, M. L., Lin, L., Solberg, T. D., Lin, A. & Hyer, D. E. (2016). Toward improved target conformity for two spot scanning proton therapy delivery system using dynamic collimation. Med Phys, 43(3), 1421-1427. PMID: 26936726.

Dalhart, A., Hyer, D., Allen, B., Flynn, R. & Johnston, H. (2016). SBRT Lung: Moving Beyond the 3D Conformal Paradigm with An Elekta VersaHD Accelerator. (Vols. 43). (6), pp. 3612-3612. Med Phys. DOI: 10.1118/1.4956831.

Flynn, R. (2016). Accounting for MV Imaging Dose and the Future of MV Imaging. (Vols. 43). (6), pp. 3741-3741. Med Phys. DOI: 10.1118/1.4957454.

Dadkhah, H., Wu, X., Kim, Y. & Flynn, R. (2016). Multi-Source Rotating Shield Brachytherapy Apparatus for Prostate Cancer. (Vols. 43). (6), pp. 3810-3810. Med Phys. DOI: 10.1118/1.4957813.

Prajapati, S., Mo, X., Bednarz, B., Lawless, M., Hammer, C., Flynn, R., Westerly, D., Jeraj, R. & Mackie, T. (2016). Development and Validation of Dose Calculation for An Open-Source KV Treatment Planning System for Small Animal Radiotherapy. (Vols. 43). (6), pp. 3617-3618. Medical Physics. DOI: 10.1118/1.4956853.

Wears, B., Mohiuddin, I., Flynn, R., Waldron, T., Kim, Y., Allen, B. & Xia, J. (2016). Development of a Novel Scanning Beam Low-Energy Intraoperative Radiation Therapy (SBIORT) System for Pancreatic Cancer. (Vols. 43). (6), pp. 3814-3814. Med Phys. DOI: 10.1118/1.4957839.

Wang, D., Smith, B. R., Gelover, E., Flynn, R. T. & Hyer, D. E. (2015). A method to select aperture margin in collimated spot scanning proton therapy. Phys Med Biol, 60(7), N109-119. PMID: 25776926.

Dadkhah, H., Kim, Y., Wu, X. & Flynn, R. T. (2015). Multi-Helix Rotating Shield Brachytherapy for Cervical Cancer. Med Phys, 42(11), 6579-6588. PMID: 26520749.

Gelover, E., Wang, D., Hill, P. M., Flynn, R. T., Gao, M., Laub, S., Pankuch, M. & Hyer, D. E. (2015). A method for modeling laterally asymmetric proton beamlets resulting from collimation. Med Phys, 42(3), 1321-34. PMID: 25735287.

Wang, D., Nixon, E., Oldham, A., Flynn, R. & Buatti, J. (2015). Personalized imaging in radiation oncology. In regard to Zhang et al. Int J Radiat Oncol Biol Phys, 211(93). PMID: 26279039.

Liu, Y., Flynn, R. T., Kim, Y., Dadkhah, H., Bhatia, S. K., Buatti, J. M., Xu, W. & Wu, X. (2015). Paddle-based rotating-shield brachytherapy. Med Phys, 42(10), 5992-6003.

Gelover, E., Moignier, A., Smith, B., Wang, D., Flynn, R., Lin, L., Kirk, M., Solberg, T. & Hyer, D. (2015). Combining collimation with spot-scanning proton therapy to improve brain treatments. St. Louis MO: AAPM Spring Clinical Meeting.

Morel, P., Wu, X., Blin, G., Vialette, S., Flynn, R. T., Hyer, D. & Wang, D. (2015). Spot weight adaptation for moving target in spot scanning proton therapy. Front Oncology, 5(119), 1-7.

Morel, P., Flynn, R. T., Gelover-Reyes, E., Blin, G., Vialette, S., Wu, X. & Wang, D. (2015). MSOT: An open-source motion simulator for proton therapy. Biomedical Physics & Engineering Express, 1(03700), 1-7.

Moigner, A., Gelover, E., Wang, D., Flynn, R., Kirk, M., Lin, L., Solberg, T., Lin, A. & Hyer, D. (2015). Benefits of Collimation in Head and Neck Cancers Treated with Spot Scanning Proton Therapy. ASTRO, San Antonio TX.

Hyer, D., Wang, D., Moignier, A., Gelover, E., Lin, L., Kirk, M., Solberg, T. & Flynn, R. (2015). A Dynamic Collimation System for Spot Scanning Proton Therapy: Design and potential Benefits for Brain Treatments. ASTRO, San Antonio TX.

Dadkhah, H., Flynn, R., Wu, X. & Kim, Y. (2015). Multi-Helix Rotating Shield Brachytherapy for Cervical Cancer. AAPM.

Moignier, A., Gelover, E., Wang, D., Flynn, R., Kirk, M., Lin, L., Solberg, T., Lin, A. & Hyer, D. (2015). Theoretical benefits of dynamic collimation in pencil beam scanning proton therapy for brain tumors: dosimetric and radiobiological metrics. pp. S0360-3016. International Journal of Radiation Oncology Biology Physics. PMID: 26614424.

Renaud, M., Flynn, R., Seuntjens, I. & Enger, S. (2015). Rotating Shield High Dose Rate Brachytherapy with 153Gd and 75Se Isotopes. AAPM.

Moignier, A., Gelover, E., Wang, D., Flynn, R., Kirk, M., Lin, L., Solberg, T., Lin, A. & Hyer, D. (2015). Therapeutic Benefits of Collimation in Spot Scanning Proton Therapy in the Treatment of Brain Cancer. AAPM.

Smith, B., Gelover, E., Wang, D., Moignier, A., Flynn, R., Lin, L., Kirk, M., Solberg, T. & Hyer, D. (2015). Collimation Methods in Spot Scanning Proton Therapy: A Treatment Plan Comparison Between A Fixed Aperture and a Dyamic System. AAPM.

Li, X., Adams, Q. & Flynn, R. (2014). Dosimetric Validation of a Partially-Shielded Gd-153 Brachytherapy Concept. Austin TX: AAPM.

Ma, M., Bayouth, J., Flynn, R. & Xia, J. (2014). Dose Recomputation Versus Dose Deformation for Stereotactic Body Radiation Therapy in Lunc Tumors: A Dosimetric Study. Austin TX: AAPM.

Wang, D., Dirksen, B., Hyer, D. E., Buatti, J. M., Sheybani, A., Dinges, E., Felderman, N., TenNapel, M., Bayouth, J. E. & Flynn, R. T. (2014). Impact of spot size on plan quality of spot scanning proton radiosurgery for peripheral brain lesions. Med Phys, 41(12), 121705. PMID: 25471952.

Adams, Q. E., Xu, J., Breitbach, E. K., Li, X., Enger, S. A., Rockey, W. R., Kim, Y., Wu, X. & Flynn, R. T. (2014). Interstitial rotating shield brachytherapy for prostate cancer. Med Phys, 41(5), 051703. PMID: 24784369.

Li, H., Bai, J., Wu, X., Bhatia, S. K., Abu-Hejleh, T., Sun, W., TenNapel, M. J., Menda, Y., Mart, C. J., McGuire, S. M. & Flynn, R. T. (2014). Semi-Automated Co-Segmentation of Tumor Volume Using Multimodality PET-CT in Non-Small Cell Lung Cancer (NSCLC). Austin Journal of Cancer and Clinical Research, 1(3), 1-6.

Wang, D., Smith, B., Hill, P., Gelover, E., Flynn, R. & Hyer, D. (2014). Determining the Optimal Collimator Position for Collimated Pencil Beam Scanning Proton Therapy. Austin TX: AAPM.

Hyer, D. E., Hill, P. M., Wang, D., Smith, B. R. & Flynn, R. T. (2014). Effects of spot size and spot spacing on lateral penumbra reduction when using a dynamic collimation system for spot scanning proton therapy. Phys Med Biol, 59(22), N187-96. PMID: 25330783.

Hyer, D., Hill, P., Wang, D., Smith, B. & Flynn, R. (2014). A Dynamic Collimation System for Spot Scanned Proton Therapy: Conceptual Overview. Austin TX: AAPM.

Ma, M., Rouabhi, O., Bayouth, J., Flynn, R. & Xia, J. (2014). A Dosimetric Analysis of 3D versus 4D Image-Based Dose Calculation for Stereotactic Body Radiation Therapy in Lung Tumors. Austin TX: AAPM.

Liu, Y., Flynn, R. T., Kim, Y. & Wu, X. (2014). Asymmetric dose-volume optimization with smoothness control for rotating-shield brachytherapy. Med Phys, 41(11), 111709. PMID: 25370623.

Hyer, D. E., Hill, P. M., Wang, D., Smith, B. R. & Flynn, R. T. (2014). A dynamic collimation system for penumbra reduction in spot-scanning proton therapy: proof of concept. Med Phys, 41(9), 091701. PMID: 25186376.

Hill, P., Wang, D., Flynn, R. & Hyer, D. (2014). The Effects of a Dynamic Collimation System on Proton Pencil Beams to Improve Lateral Tissue Sparing in Spot Scanned Proton Therapy. Austin TX: AAPM.

Gelover, E., Wang, D., Hill, P., Flynn, R. & Hyer, D. (2014). Analytical Modeling and Dose Calculation Method for Asymmetric Proton Pencil Beams. Austin TX: AAPM.

Moghaddas, T. A., Ghorbani, M., Haghparast, A., Flynn, R. T. & Eivazi, M. T. (2014). A Monte Carlo Study on Dose Enhancement Effect of Various Paramagnetic Nanoshells in Brachytherapy. J Med Biol Eng, 34(6), 559-567. DOI: 10.5405/jmbe.1769.

Liu, Y., Flynn, R., Kim, Y. & Wu, X. (2013). Inverse Optimization Using Smoothness Control for Rotating Shield Brachytherapy. Indianapolis IN: AAPM.

Yang, W., Kim, Y., Wu, X., Song, Q., Liu, Y., Bhatia, S. K., Sun, W. & Flynn, R. T. (2013). Rotating-shield brachytherapy for cervical cancer. Phys Med Biol, 58(11), 3931-41. PMID: 23680601.

Dirksen, B., Wang, D., Hyer, D., Buatti, J. M., Sheybani, A., TenNapel, M., Bayouth, J. & Flynn, R. (2013). Radiosurgery of Peripheral Brain Lesions by Spot Scanning Proton Therapy. Indianapolis IN: AAPM.

Flynn, R., Li, X., Kim, Y., Wu, X., Townsend, K., Zhang, W., Woodin, B., Rockey, W., Enger, S. A., Breitbach, E. K. & Adams, Q. (2013). Interstitial Rotating Shield Brachytherapy for Prostate Cancer. Indianapolis IN: AAPM.

Liu, Y., Flynn, R. T., Yang, W., Kim, Y., Bhatia, S. K., Sun, W. & Wu, X. (2013). Rapid emission angle selection for rotating-shield brachytherapy. Med Phys, 40(5), 051720. PMID: 23635268.

Li, X., Pike, T. & Flynn, R. (2013). Experimental Verification of a Compensator-Based Brachytherapy System. Indianapolis IN: AAPM.

Liu, Y., Flynn, R. T., Kim, Y., Yang, W. & Wu, X. (2013). Dynamic rotating-shield brachytherapy. Med Phys, 40(12), 121703. PMID: 24320489.

Anderson, J. W., Xia, J., Flynn, R. T., Modrick, J. M., Bhatia, S. K., Jacobson, G. M. & Kim, Y. (2013). High resolution (3 Tesla) MRI-guided conformal brachytherapy for cervical cancer: consequences of different high-risk CTV sizes. J Contemp Brachytherapy, 5(2), 101-9. PMID: 23878555.

Becker, S. J., Culberson, W. & Flynn, R. T. (2013). Collision indicator charts for gantry-couch position combinations for Siemens ONCOR and Elekta Infinity linacs. J Appl Clin Med Phys, 14(5), 278-83. PMID: 24036873.

Huang, Y., Flynn, R. T., Siochi, R. A. & Bayouth, J. E. (2013). Equivalent-quality unflattened photon beam modeling, planning, and delivery. J Appl Clin Med Phys, 14(4), 4211. PMID: 23835385.

Enger, S. A., Fisher, D. R. & Flynn, R. T. (2013). Gadolinium-153 as a brachytherapy isotope. Phys Med Biol, 58(4), 957-64. PMID: 23339848.

Edwards, D. S., Kim, Y., Wu, X. & Flynn, R. (2012). Giving Hope to Cervical Cancer Patients with Multiple-Rotating Shield Brachytherapy (MRS-IMBT). Des Moines, Iowa: Research in the Capitol, Iowa State Capitol.

Sun, W., Bhatia, S. K., Jacobson, G. M., Flynn, R. T. & Kim, Y. (2012). Target volume changes through high-dose-rate brachytherapy for cervical cancer when evaluated on high resolution (3.0 Tesla) magnetic resonance imaging. Pract Radiat Oncol, 2(4), e101-6. PMID: 24674171.

Kissick, M. W., Mackie, T. R., Flynn, R. T., Mo, X., Campos, D. D., Yhan, Y. & Zhao, D. (2012). Investigation of probabilistic optimization for tomotherapy. (Vols. 13). (5), pp. 3865. Journal of Applied Clinical Medical Physics/American College of Medical Physics. PMID: 22955654.

Bayouth, J., Huang, Y., Flynn, R. & Siochi, R. (2012). A Clinical Review of the Dosimetric and Temporal Impact of Unflattened X-ray Beams. Charlotte NC: AAPM.

Liu, Y., Flynn, R., Yang, W., Kim, Y. & Wu, X. (2012). Optimal Emission Angel Selection in Rotating Shield Brachytherapy. Charlotte NC: AAPM.

Kissick, M. W., Flynn, R. T., Mo, X., Campos, D. D., Mackie, T. R., Yan, Y. & Zhao, D. (2012). Probabilistic optimization should be efficacious for tomotherapy. J Appl Clin Med Phys, 13(5), 155-169.

Yang, W., Kim, Y., Liu, Y., Wu, X. & Flynn, R. (2012). Rotating Shield Brachytherapy (RSBT) for Cervical Cancer. Charlotte NC: AAPM Meeting.

Kim, Y., Muruganandham, M., Flynn, R., Modrick, J. & Jacobson, G. (2012). MRI Guided, Conformal Brachytherapy for Cervical Cancer. Dallas Texas: AAPM.

Zhang, M., Flynn, R. T., Mo, X. & Mackie, T. R. (2012). The energy margin strategy for reducing dose variation due to setup uncertainty in intensity modulated proton therapy (IMPT) delivered with distal edge tracking (DET). J Appl Clin Med Phys, 13(5), 170-180. PMID: 22955652.

Westerly, D. C., Schefter, T. E., Kavanagh, B. D., Chao, E., Lucas, D., Flynn, R. T. & Miften, M. (2012). High-dose MVCT image guidance for stereotactic body radiation therapy. Med Phys, 39(8), 4812-9. PMID: 22894407.

Huang, Y., Flynn, R., Siochi, A. & Bayouth, J. (2011). Reduction of treatment time in clinical SBRT delivered with unflattened photon beam. London UK: 11th Biennial ESTRO Meeting.

Huang, Y., Flynn, R., Siochi, A. & Bayouth, J. (2011). Reduction of treatment time in clinical SBRT delivered with unflattened photon beam. 11th Biennial ESTRO Meeting, London UK.

Edwards, D. S., Kim, Y., Wu, X. & Flynn, R. T. (2011). Sequencing method to reduce treatment time for intensity modulated brachytherapy. Vancouver BC Canada: Joint AAPM-COMP meeting.

Kissick, M. W., Flynn, R. T., Mackie, T. R., Mo, X., Zhao, D., Campos, D. & Yan, Y. (2011). The potential of probabilistic optimization for tumor motion with IMRT. Vancouver BC Canada: Joint AAPM and COMP meeting.

Breitbach, E. K., Maltz, J. S., Gangadharan, B. S., Bani-Hashemi, A. R., Anderson, C. M., Bhatia, S. K., Stiles, J. M., Edwards, D. S. & Flynn, R. T. (2011). Reducing megavoltage cone beam CT imaging dose without loss of spatial resolution using a sintered pixelated array system. Vancouver BC Canada: Joint AAPM-COMP meeting.

Breitbach, E. K., Maltz, J. S., Gangadharan, B., Bani-Hashemi, A., Anderson, C. M., Bhatia, S. K., Stiles, J., Edwards, D. S. & Flynn, R. T. (2011). Image quality improvement in megavoltage cone beam CT using an imaging beam line and a sintered pixelated array system. Med Phys, 38(11), 5969-79. PMID: 22047361.

Liu, Y., Flynn, R. T., Kim, Y. & Wu, X. (2011). Optimal sequencing to reduce treatment time while improving the quality of intensity-modulated brachytherapy with fixed-angular fan-beams. Vancouver BC Canada: Joint AAPM-COMP Meeting.

Liu, Y., Flynn, R., Kim, Y. & Wu, X. (2011). Dynamic-shield intensity-modulated brachytherapy (IMBT) for cervical cancer. Miami FL: ASTRO.

Flynn, R., Kim, Y. (2011). Compensator-based intensity modulated brachytherapy. London UK: 11th Biennial ESTRO Meeting.

Bayouth, J. E., Flynn, R. T. & Smith, M. C. (2011). Megavoltage cone-beam computed tomography-guided intensity modulated radiation therapy in a prostate cancer patient treated on a Siemens Oncor Linear Accelerator. In , A. J. Mundt & J. C. Roeske (Eds.) Image-Guided Radiation Therapy: A Clinical Perspective, 1st ed..

Flynn, R. T., Kim, Y., Jacobson, G. & Wu, X. (2011). Compensator-based intensity modulated brachytherapy for cervical cancer. Vancouver BC Canada: Joint AAPM-COMP Meeting.

Flynn, R. (2010). Loss of radiobiological effect of imaging dose in image guided radiotherapy due to prolonged imaging-to-treatment times. Med Phys, 37(6), 2761-2769. PMID: 20632586.

Flynn, R., Edwards, D., Stiles, J., Maltz, J., Gangadharan, B. & Bani-Hashemi, A. (2010). Image quality improvement in megavoltage cone beam CT using an ultrafast ceramic scintillator system. Philadelphia PA: AAPM Annual Meeting.

Barbee, D. L., Flynn, R. T., Holden, J. E., Nickles, R. J. & Jeraj, R. (2010). A method for partial volume correction of PET-imaged tumor heterogeneity using expectation maximization with a spatially varying point spread function. Phys Med Biol, 55(1), 221-36. PMID: 20009194.

Schwerter, A., Guan, J., Ying, X., Pelland, D., Morris, A. & Flynn, R. T. (2010). Reducing Excess Imaging Dose to Cancer Patients Receiving Radiotherapy. Des Moines IA: Research in the Capitol.

Schwertner, A., Guan, J., Ying, X., Pelland, D., Morris, A. & Flynn, R. (2010). Dosimetric benefits of the imaging dose incorporation (IDI) method for megavoltage cone beam CT (MVCBCT) in head and neck patients. Philadelphia PA: AAPM National Meeting.

Bowen, S. R., Flynn, R. T., Bentzen, S. M. & Jeraj, R. (2009). On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function. Phys Med Biol, 54(6), 1483-501. PMID: 19218733.

Huang, Y., Flynn, R., Siochi, R. & Bayouth, J. (2009). Quality evaluation of unflattened photon beam model. AAPM National Meeting - Anaheim CA.

Flynn, R. (2009). Loss of radiobiological effect of imaging dose in IGRT due to prolonged imaging-to-treatment time. Maastricht, The Netherlands: 10th Biennial ESTRO Conference on Physics and Radiation Technology for Clinical Radiotherapy..

Kissick, M., Mo, X., Westerly, D., Flynn, R., Bowen, S., Schubert, L., Jeraji, R. & Mackie, T. (2009). Tomotherapy dose painting delivery robust to respiratory motion. Anaheim CA: AAPM National Meeting.

Nelms, D., Shukla, H., Nixon, E., Bayouth, J. E. & Flynn, R. (2009). Quantitative assessment of three dead detector interpolative correction methods for cone beam CT images. Anaheim CA: AAPM National Meeting.

Bayouth, J., Huang, Y. & Flynn, R. (2009). Non-flattened beam planning and delivery for gated hypo-fractionated IMRT in liver cancer. Chicago IL: ASTRO Annual Meeting.

Barbee, D., Bowen, S., Flynn, R., Holden, J. & Jeraj, R. (2009). Assessing the impact of partial volume correction on dose painting. Anaheim CA: AAPM National Meeting.

Flynn, R., Hartmann, J., Bani-Hashemi, A., Nixon, E., Siochi, R., Pennington, E. & Bayouth, J. (2009). Dosimetric characterization of an imaging beam line with a carbon electron target for megavoltage cone beam computed tomography. Anaheim CA: AAPM National Meeting.

Nelms, D. W., Flynn, R. T. (2009). Correction of dead detector pixels in 3D imaging for cancer radiation therapy. Des Moines IA: Research in the Capitol.

Nelms, D. W., Shukla, H. I., Nixon, E., Bayouth, J. E. & Flynn, R. (2009). Assessment of three dead detector correction methods for cone beam computed tomography. Med Phys, 36(10), 4569-4576. PMID: 19928088.

Flynn, R., Hartmann, J., Bani-Hashemi, A., Nixon, E., Siochi, R. A., Pennington, E. C. & Bayouth, J. E. (2009). Dosimetric characterization and application of an imaging beam line with a carbon electron target for megavoltage cone beam computed tomography. Med Phys, 36(6), 2181-2192. PMID: 19610307.

Barbee, D. L., Flynn, R. T., Holden, J. E. & Jeraji, R. (2008). Partial volume correction of PET-imaged tumor heterogeneity using expectation maximization. Houston TX: AAPM Annual Meeting.

Flynn, R. T., Bowen, S. R., Bentzen, S. M., Rockwell Mackie, T. & Jeraj, R. (2008). Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting. Phys Med Biol, 53(15), 4153-67. PMID: 18635895.

Flynn, R. T., Kissick, M. W., Mehta, M. P., Olivera, G. H., Jeraj, R. & Mackie, T. R. (2008). The impact of linac output variations on dose distributions in helical tomotherapy. Phys Med Biol, 53(2), 417-30. PMID: 18184996.

Kissick, M. W., Flynn, R. T., Westerly, D. C., Hoban, P. W., Mo, X., Soisson, E. T., McCall, K. C., Mackie, T. R. & Jeraji, R. (2008). The Impact of Longitudinal Breathing Randomness for Tomotherapy Delivery. Houston TX: AAPM Annual Meeting.

Caporaso, G. J., Mackie, T. R., Sampayan, S., Chen, Y., Blackfield, D., Harris, J., Hawkins, S., Holmes, C., Nelson, S., Paul, A., Poole, B., Rhodes, M., Sanders, D., Sullivan, J., Wang, L., Watson, J., Reckwerdt, P. J., Schmidt, R., Pearson, D., Flynn, R., Matthews, D. & Purdy, J. (2008). A compact linac for intensity modulated proton therapy based on a dielectric wall accelerator. Phys Med, 24(2), 98-101. PMID: 18430600.

Flynn, R. T., Shukla, H. I., Nixon, E. & Bayouth, J. E. (2008). A quantitative assessment of the effects of a simple dead detector pixel correction method for megavoltage cone beam CT images. Houston TX: AAPM Annual Meeting.

Kissick, M. W., Flynn, R. T., Westerly, D. C., Hoban, P. W., Mo, X., Soisson, E. T., McCall, K. C., Mackie, T. R. & Jeraj, R. (2008). On the impact of longitudinal breathing motion randomness for tomotherapy delivery. Phys Med Biol, 53(18), 4855-73. PMID: 18711250.

Bowen, S. R., Flynn, R. T., Bentzen, S. M. & Jeraji, R. (2008). Impact of Prescription Dose Gradient Discretization on Dose Painting. Houston TX: AAPM Annual Meeting.

Dirksen, B. M., Flynn, R. T., Svare, C., Goodin, F. L. & Frigo, S. P. (2008). Clinical impact of applying heterogeneity correction to dose calculations for esophageal sites. Houston TX: AAPM Annual Meeting.

Jeraj, R., Simoncic, U., Flynn, R. T. & Bowen, S. R. (2008). Dosimetric differences for dose painting, based on SUV or KFLT FLT-PET image ratio. Houston TX: AAPM Annual Meeting.

Kissick, M., Flynn, R., Westerly, D., Jeraji, R. & Mackie, R. (2007). One Vision of the Next Generation of Helical Tomotherapy. Minneapolis MN: AAPM National Meeting.

Kissick, M. W., Flynn, R. T., Westerly, D. C., Mackie, T. R. & Hoban, P. W. (2007). On the making of sharp longitudinal dose profiles with helical tomotherapy. Phys Med Biol, 52(21), 6497-510. PMID: 17951858.

Kissick, M., Flynn, R., Hoban, P., Westerly, D. & Mackie, T. (2007). Optimizing Sharp Longitudinal Tomotherapy Dose Distribution. Toronto ON, Canada: ICCR International Conference, Abstract 88.

Westerly, D., Flynn, R., Hill, P. & Mackie, T. (2007). Modeling the use of Magnetic Quadrupoles for Ion Fan-Beam Production. Toronto ON Canada: ICCR International Conference, Abstract 41.

Flynn, R., Tomm, W., Gutierrez, A., Westerly, D., Jeraj, R. & Mackie, T. (2007). Whole brain radiation therapy with conformal avoidance of the hippocampus: a comparison of x-ray Tomotherapy to proton therapy with distal edge tracking and spot spanning. Proceedings of ICCR International Conference, Toronto Canada.

Flynn, R., Tome, W., Gutierrez, A., Westerly, D., Jeraji, R. & Mackie, T. (2007). Whole brain radiation therapy with conformal avoidance of the hippocampus: a comparison of x-ray tomotherapy to proton therapy with distal edge tracking and spot scanning. Toronto ON Canada: ICCR International Conference.

Bowen, S., Flynn, R., Bentzen, S. & Jeraj, R. (2007). Effect of a Biologically-based Prescription Function in IMRT Dose Optimization. Minneapolis MN: AAPM Annual Meeting.

Flynn, R. T., Barbee, D., Jeraji, R. & Mackie, T. R. (2007). A Phantom Study of Selective Subvolume Boosting with Intensity Modulated Proton Therapy and Intensity Modulated X-ray Therapy. Wanjie Zibo China: Proton Therapy Co-Operative Group Conference.

Mackie, T., Caporaso, G. J., Chen, Y., Blackfield, D., Harris, J., Hawkins, S., Holmes, C., Nelson, S., Paul, A., Poole, B., Rhodes, M., Sanders, D., Sullivan, J., Wang, L., Watson, J., Reckwerdt, P., Schmidt, R., Pearson, D., Flynn, R., Matthews, D. & Purdy, J. (2007). A Proposal for a Novel Compact Intensity Modulated Proton Therapy System using a Dielectric Wall Accelerator. Minneapolis MN: AAPM Annual Meeting.

Flynn, R. T., Barbee, D. L., Mackie, T. R. & Jeraj, R. (2007). Comparison of intensity modulated x-ray therapy and intensity modulated proton therapy for selective subvolume boosting: a phantom study. Phys Med Biol, 52(20), 6073-91. PMID: 17921573.

Flynn, R., Barbee, D., Bowen, S., McCall, K., Bentzen, S., Mackie, T. & Jeraj, R. (2007). Dose Painting with Intensity Modulated Proton Therapy and Intensity Modulated X-ray Therapy: a Comparison. Minneapolis MN: AAPM Annual Meeting.

Mackie, T., Flynn, R., Westerly, D., Hill, P., Kissick, M., Jeraji, R. & DeLuca, P. (2007). Distal Edge Tracking Intensity Modulated Proton Therapy Using a Fan Beam. Toronto On Canada: ICCR International Conference.

Mackie, T., Kissick, M., Flynn, R., Westerly, D., Hill, P., DeLuca, P., Jeraji, R., Schreuder, A. & Farr, J. (2006). Simultaneous multi-pencil fan-beam-based intensity modulated proton therapy. Orlando FL: AAPM Annual Meeting.

Flynn, R., Kissick, M., Jeraj, R., Mehta, M., Olivera, G., Srinavasan, S. & Mackie, T. (2006). Propagation of linac output and fluence discretization error to dose distributions in IMRT. Orlando FL: AAPM National Meeting.

Barbee, D., Flynn, R., Jaskowiak, C. & Jeraj, R. (2006). Effects of PET reconstruction parameters on the delineation of heterogeneous target volumes. Orlando FL: AAPM Annual Meeting.

Becker, S., Shaw, R., Flynn, R. & Mackie, T. (2006). A novel tomotherapy design for the breast. Orlando FL: AAPM Annual Meeting.

Flynn, R., Kissick, M., Mehta, M., Jeraji, R. & Mackie, T. (2006). An investigation of the effects of relatively large linac output variations on dose distributions for IMRT. Minneapolis MN: North Central Chapter of the AAPM Bi-Annual Meeting.

Jeraj, R., Kowalok, M., Flynn, R. & Mackie, T. R. (2005). Simulations of an image-guided radiotherapy system. The Monte Carlo Method: Versatility Unbounded in a Dynamic Computer World. Chattanooga TN.

Mackie, T., Flynn, R., Kissick, M. & Jeraj, R. (2005). An Analysis of intensity discretization errors in IMRT. Seattle WA: AAPM Annual Meeting.

Flynn, R., Jeraj, R. & Mackie, T. (2005). A probabilistic method for online treatment plan modification. Seattle WA: AAPM Annual Meeting.

Flynn, R., Unkelbach, J., Oelfke, U., Jeraj, R. & Mackie, T. (2005). A comparison of two probabilistic methods for intra-fractional re-optimization in IMRT. Lisbon Portugal: Biennial ESTRO meeting.

Kowalok, M., Jeraj, R., Bohm, T., Flynn, R., Mackie, T. & Henderson, D. (2004). Iterative adjoint and forward Monte Carlo transport for external beam treatment planning. Pittsburgh PA: AAPM Meeting.

Flynn, R., Jeraj, R., Kowalok, M. & Mackie, T. (2004). Construction of a tomotherapy beam model based on thick target bremsstrahlung and Monte Carlo derived parameters. Pittsburgh PA: AAPM Annual Meeting.