William M. Rockey, MD, PHD

Portrait
Clinical Assistant Professor, Department of Radiation Oncology
Clinical Assistant Professor of Radiation Oncology

Contact Information

Education

BS, Chemical Engineering, Iowa State University, Ames, IA
MD, University of Iowa, Iowa City, IA
PhD, Biochemistry, University of Iowa, Iowa City, IA

Resident, Internal Medicine, University of Iowa, Iowa City, IA
Resident, Radiation Oncology, University of Iowa, Iowa City, IA

Licensure and Certifications

Clinical Radiation Oncology exam - American Board of Radiology
ABR Physics and Radiobiology exam - American Board of Radiology

Publications

Urak, K. T., Shore, S., Rockey, W. M., Chen, S., McCaffrey, A. & Gigangrande, P. (2016). In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs. Methods, 103, 167-174. PMID: 26972786.

Kim, Y., Rockey, W. M. (2015). High Dose Rate Brachytherapy for Localized Prostate Cancer: An Opportunity for Improvement over Intensity-Modulated Radiotherapy. Austin J Cancer Clin Res, 2(2), 1027.

Adams, Q. E., XU, J. Z., Breitbach, E. K., Li, X., Enger, S. A., Rockey, W. M., Kim, Y., Wu, X. D. & Flynn, R. T. (2014). Interstitial Rotating Shield Brachytherapy for Prostate Cancer. Medical Physics, 41(5). PMID: 24784369.

Dassie, J. P., Thomas, G. S., Long, M. E., Rockey, W. M., Howell, C. A., Chen, Y. N., Hernandez, F. J., Wilson, M. E., Allen, L. A., Vaena, D. A., Meyerholf, D. K. & Giangrande, P. H. (2014). Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane antigen. Mol Ther, 22(11), 1920-22. PMID: 24954476.

Julius, B., Rahmani, D., Rockey, W. M., Tracy, C., Nixon, E., Modrick, J., Sander, E. & Kim, Y. (2013). Development of a Low-Cost, Easily Made, Interchangeable, Prostate Brachytherapy Phantom for Multi-Imaging Guidance Using Ultrasound, CT and MRI. (Vols. 40). (6), pp. 157. Med Phys.

Rockey, W. M., Bhatia, S. K., Jacobson, G. M. & Kim, Y. (2013). The Dosimetric Impact of Vaginal Balloon Packing on Intracavitary High Dose Rate Brachytherapy for Gynecological Cancer. J Contemp Brachytherapy, 5(1), 17-22. PMID: 23634151.

Hernandex, L. I., Rockey, W. M. & Howell, C. A. (2013). Targeted, Multifunctional RNA Therapies for Advanced Cancers of the Prostate. In Meeting Abstract 509. (Vols. 21). pp. S197-S197. Molecular Therapy.

Gourronc, F. A., Rockey, W. M., Thiel, W. H., Giangrande, P. H. & Klingelhutz, A. J. (2013). Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells. Virology, 446(1-2), 325-33. PMID: 24074596.

Song, Q., Bai, J., Bhatia, S., Sun, W., Rockey, W. M., Bayouth, J., Buchkina, J. R. & Wu, X. (2013). Optimal Co-segmentation of Tumor in PET-CT Images with Context Information. IEEE Transactions on Medical Imaging. PMID: 23693127.

Hernandex, L. I., Rockey, W. M., Howell, C. A., Liu, X. Y., McNamara, J. O. & Giangrande, P. H. (2012). Detection Methods for In Vitro and In Vivo Characterization of Cell-Specific, Cell-Internalizing RNA Aptamers for siRNA Delivery. (Vols. S1). pp. S133-S133. Molecular Therapy.

Rockey, W. M., Bhatia, S. K., Jacobson, G. M. & Kim, Y. (2011). The dosimetric impact of vaginal balloon packing on brachytherapy for gynecological cancer. ASTRO, 53rd Annual Meeting, Miami, FL..

Rockey, W. M., Hernandex, F., Huang, S., Cao, S., Howell, C., Thomas, G., Liu, X., Lapteva, N., Spencer, D., McNamara II, J., Zou, X., Chen, S. & Giangrande, P. (2011). Rational truncation of an RNA aptamer to prostate specific membrane antigen using computional structural modeling. Nucleic Acid Ther, 21(5), 299-314. PMID: 22004414.

Rockey, W. M., Huang, L., Kloepping, K. C., Baumhover, N. J., Giangrande, P. H. & Schultz, M. K. (2011). Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. Bioorg Med Chem, 19(13), 4080-90. PMID: 21658962.

Dassie, J. P., Rockey, W. M., Hernandez, F. J., Huang, S. Y., Cao, S., Howell, C. A., Hernandez, L. I., Thomas, G. S., Liu, X. Y., Lapteva, N., Spencer, D. M., McNamara, J. O., Zou, X. Q., Chen, S. J. & Giangrade, P. H. (2011). Computer-Guided Optimization of an RNA Aptamer for Clinical Applications. (Vols. 21). (5), pp. A5-A5. Nucleic Acid Therapeutics.

Thiel, W. H., Bair, T., Thiel, K. W., Dassie, J. P., Rockey, W. M., Liu, X. Y., Behlke, A. J., McNamara, J. O. & Giangrande, P. H. (2011). Nucelotide bias observed with a short SELEX RNA aptamer library. Nucleic Acid Ther, 21(4), 253-63. PMID: 21793789.

Rockey, W. M., Walsh, S., Liu, X. y., Sunderlan, J., Meyerholz, D. K., Thedens, D. R., McNamara, J. O., Schultz, M. K. & Giangrande, P. H. (2010). Development of an RNA-based SPECT/CT imaging agent for prostate cancer. (Vols. 78). (3), pp. S163. Int J Radiat Oncol Biol Phys.

Rockey, W. M., Elcock, A. H. (2006). Rapid computational identification of the targets of protein kinase inhibitors. Curr Opin Durg Discov Devel, 9(3), 326-31. PMID: 16729728.

Rockey, W. M., Elcock, A. H. (2006). Rapid computational identification of the targets of protein kinase inhibitors. Curr Opin Drug Discov Devel, 9(3), 326-31. PMID: 16729728.

Rockey, W. M., Elcock, A. H. (2006). Structure selection for protein kinase docking and virtual screening: Homology models or crystal strutures?. Curr Protein Pept Sci, 7(5), 437-57. PMID: 17073695.

Rockey, W. M., Elcock, A. H. (2005). Rapid computational identificaton of the targets of protein kinase inhibitors. J Med Chem, 48(12), 4138-52. PMID: 15943486.

Rockey, W. M., Elcock, A. H. (2002). Progress toward virtual screening for drug side effects. Proteins, 48(4), 664-71. PMID: 12211034.

Rockey, W. M., Elcock, A. H. (2002). Progress toward Virtual Screening for Drug Side Effects.

Rockey, W. M., Dowd, M. K., Reilly, P. J. & French, A. D. (2001). Modeling of deoxy- and dideoxyaldohexopyranosyl ring puckering with MM3(92). Carbohydrate Research, 335(4), 261-73. PMID: 11595220.

Dowd, M. K., Rockey, W. M., French, A. D. & Reilly, P. J. (2000). Aldopentose Ring Puckering with MM3. Abstract A187.

Rockey, W. M., Laederach, A. & Reilly, P. J. (2000). Automated docking of alpha-(1?4)- and alpha-(1?6)- linked glucosyl trisaccharides and maltopentaose into the soybean beta-amylase active site. Proteins, 40(2), 299-309. PMID: 10842343.

Rockey, W. M., Laederach, A. & Reilly, P. J. (1999). Automated docking of alpha-(1?4)- and alpha-(1?6)- linked glucosyl trisaccharides and maltopentaose into the soybean beta-amylase active site.