Investigator Laboratories

FRRBP Investigator laboratories

photo Spitz Allen labAllen-Spitz lab:

Dr. Allen's lab focuses on understanding the basic science mechanisms by which pharmacological ascorbate can selectively act as a pro-oxidant in brain and lung cancer vs. normal cells, for the purpose of developing novel combined modality chemo-radio-therapies.

 

photo Buettner labBuettner lab:

Our labs interest is in exploring the fundamental chemistry and biochemistry of vitamins C and E. Nitric Oxide is being investigated (NIH funded) as an important membrane antioxidant in cells and tissue. We hypothesize that it is as important as Vitamin E.

 

photo Cullen labCullen lab:

Adenocarcinoma of the pancreas is the fourth leading cause of cancer death in the United States and is increasing in incidence. Intravenous ascorbate (high dose vitamin C), but not oral ascorbate, produces high plasma concentrations, which are in the range that are cytotoxic to tumor cells.

 

photo Goswami labGoswami lab:

Dr. Goswami's laboratory is pursuing basic science research in the field of free radical biology of the mammalian cell cycle, aging and cancer. His laboratory first reported the presence of a “redox cycle” within the mammalian cell cycle that integrates cellular metabolism to cell cycle progression.

 

photo Schultz labSchultz lab:

Dr. Schultz's research interests involve the development of synthetic-bioactive molecular targeting vectors for imaging and therapy of cancer. Molecular targeting involves identification of G-protein coupled receptors and other cell surface antigens and the development of targeting vectors that selectively bind to these antigens.

 

 

Spitz lab photo

Spitz lab:

The long-term goal of this laboratory’s efforts are to use a basic science understanding of the mechanisms associated with free radical biology to elucidate novel methods for manipulating clinically significant outcomes in areas of medicine relevant to cancer biology and degenerative diseases associated with aging.