Kenneth G. Nepple, MD

Clinical Associate Professor of Urology

Contact Information

Primary Office
3228 RCP
Iowa City, IA 52242


BS, Psychology, Iowa State University
MD, Medicine, University of Iowa
Resident, Urology, University of Iowa
Fellow, Urologic Oncology, Washington Unversity


Swanton, A. R., Alzubaidi, A. N., Han, Y., Nepple, K. G. & Erickson, B. A. (2017). Trends in Operating Room Assistance for Major Urologic Surgical Procedures: An Increasing Role for Advanced Practice Providers. Urology, 106, 76-81. PMID: 28499759.

Steinberg, R. L., Thomas, L. J. & Nepple, K. G. (2016). Intravesical and alternative bladder-preservation therapies in the management of non-muscle-invasive bladder cancer unresponsive to bacillus Calmette-Guérin. Urologic oncology, 34(6), 279-89. PMID: 26777259.

Velaer, K. N., Steinberg, R. L., Thomas, L. J., O'Donnell, M. A. & Nepple, K. G. (2016). Experience with Sequential Intravesical Gemcitabine and Docetaxel as Salvage Therapy for Non-Muscle Invasive Bladder Cancer. Current urology reports, 17(5), 38. PMID: 26968418.

Moriarty, M. A., Nepple, K. G., Tracy, C. R., Strigenz, M. E., Lee, D. K. & Brown, J. A. (2016). Impact of Robotic Fellowship Experience on Perioperative Outcomes of Robotic-Assisted Laparoscopic Partial Nephrectomy. Current urology, 9(1), 19-23. PMID: 26989366.

Eggener, S. E., Badani, K., Barocas, D. A., Barrisford, G. W., Cheng, J. S., Chin, A. I., Corcoran, A., Epstein, J. I., George, A. K., Gupta, G. N., Hayn, M. H., Kauffman, E. C., Lane, B., Liss, M. A., Mirza, M., Morgan, T. M., Moses, K., Nepple, K. G., Preston, M. A., Rais-Bahrami, S., Resnick, M. J., Siddiqui, M. M., Silberstein, J., Singer, E. A., Sonn, G. A., Sprenkle, P., Stratton, K. L., Taylor, J., Tomaszewski, J., Tollefson, M., Vickers, A., White, W. M. & Lowrance, W. T. (2015). Gleason 6 Prostate Cancer: Translating Biology into Population Health. The Journal of urology, 194(3), 626-34. PMID: 25849602.

Shah, V. S., Jung, N. L., Lee, D. K. & Nepple, K. G. (2015). Does Routine Pathology Analysis of Adult Circumcision Tissue Identify Penile Cancer?. Urology, 85(6), 1431-4. PMID: 25872693.

Moriarty, M. A., Uhlman, M. A., Bing, M. T., O'Donnell, M. A., Brown, J. A., Tracy, C. R., Deorah, S., Nepple, K. G. & Gupta, A. (2015). Evaluating the safety of intraoperative instillation of intravesical chemotherapy at the time of nephroureterectomy. BMC urology, 15, 45. PMID: 26018765.

Shah, V. S., Nepple, K. G. & Lee, D. K. (2014). Routine pathology evaluation of hydrocele and spermatocele specimens is associated with significant costs and no identifiable benefit. The Journal of urology, 192(4), 1179-82. PMID: 24768992.

Vemana, G., Nepple, K. G., Vetter, J., Sandhu, G. & Strope, S. A. (2014). Defining the potential of neoadjuvant chemotherapy use as a quality indicator for bladder cancer care. The Journal of urology, 192(1), 43-9. PMID: 24518776.

Moriarty, M. A., Dahmoush, L. & Nepple, K. G. (2014). IgG4 related disease of the ureter (inflammatory pseudotumor). The Journal of urology, 191(4), 1126-7. PMID: 24440497.

Bockholt, N. A., DeRoo, E. M., Nepple, K. G., Modrick, J. M., Smith, M. C., Fallon, B., Hass, A. C., Tracy, C. R. & Brown, J. A. (2013). First 100 cases at a low volume prostate brachytherapy institution: learning curve and the importance of continuous quality improvement. The Canadian journal of urology, 20(5), 6907-12. PMID: 24128827.

Nepple, K. G., Strope, S. A., Grubb, 3rd, R. L. & Kibel, A. S. (2013). Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urologic oncology, 31(6), 894-8. PMID: 21803615.

Johnson, M. H., Nepple, K. G., Peck, V., Trinkaus, K., Klim, A., Sandhu, G. S. & Kibel, A. S. (2013). Randomized controlled trial of oxybutynin extended release versus placebo for urinary symptoms during intravesical Bacillus Calmette-Guérin treatment. The Journal of urology, 189(4), 1268-74. PMID: 23123375.

Nepple, K. G., Kallogjeri, D. & Bhayani, S. B. (2013). Benchtop evaluation of pressure barrier insufflator and standard insufflator systems. Surgical endoscopy, 27(1), 333-8. PMID: 22833262.

Sandhu, G. S., Nepple, K. G., Tanagho, Y. S. & Andriole, G. L. (2013). Laparoscopic prostatectomy for prostate cancer: continued role in urology. Surg Oncol Clin North Am, 22, 125-41.

Johnson, M. H., Nepple, K. G. & Humphrey, P. A. (2012). Bladder lymphoma. J Urol, 188, 269-70.

Nepple, K. G., Sandhu, G. S., Rogers, C. R., Allaf, M. E., Kaouk, J. H., Figenshau, R. S., Stifelman, M. D. & Bhayani, S. B. (2012). Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy. Patient Saf Surg, 6, 8.

Nepple, K. G., Yang, L., Grubb, III, R. L. & Strope, S. A. (2012). Population based analysis of the increasing incidence of kidney cancer in the United States: evaluation of age specific trends from 1975 to 2006. J Urol, 187, 32-8.

Strope, S. A., Yang, L., Nepple, K. G., Andriole, G. L. & Owens, P. L. (2012). Population based comparative effectiveness of transurethral resection of the prostate and laser therapy for benign prostatic hyperplasia. J Urol, 187, 1341-5.

Kyllo, R. L., Tanagho, Y. S., Kaouk, J. H., Stifelman, M. D., Rogers, C. G., Hilyer, S. P., Sukumar, S. S., Nepple, K. G. & Bhayani, S. B. (2012). Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma. BMC Urol, 12, 11.

Nepple, K. G., Andriole, G. L. (2012). Prostate cancer chemoprevention with 5a-reductase inhibitors. (Vols. 30). pp. 553-4. Urol Oncol.

Tanagho, Y. S., Bhayani, S. B., Sandhu, G. S., Vaughn, N. P., Nepple, K. G. & Figenshau, R. S. (2012). Renal functional and perioperative outcomes of off-clamp versus clamped robot-assisted partial nephrectomy: matched cohort study. Urology, 80, 838-43.

Lightfoot, A. J., Rosevear, H. M., Nepple, K. G. & O'Donnell, M. A. (2012). Role of routine transurethral biopsy and isolated upper tract cytology after intravesical treatment of high-grade non-muscle invasive bladder cancer. Int J Urol, 19, 988-93.

Rosevear, H. M., Lightfoot, A. J., Birusingh, K. K., Maymí, J. L., Nepple, K. G. & O'Donnell, M. A. (2011). Factors affecting response to bacillus Calmette-Guérin plus interferon for urothelial carcinoma in situ. J Urol, 186(3), 817-23. PMID: 21788050.

Rosevear, H. M., Lightfoot, A. J., Nepple, K. G. & O'Donnell, M. A. (2011). Usefulness of the Spanish Urological Club for Oncological Treatment scoring model to predict nonmuscle invasive bladder cancer recurrence in patients treated with intravesical bacillus Calmette-Guérin plus interferon-a. J Urol, 185(1), 67-71. PMID: 21074202.

Nepple, K. G., Lightfoot, A. J., Rosevear, H. M., O'Donnell, M. A. & Lamm, D. L. (2010). Bacillus Calmette-Guérin with or without interferon a-2b and megadose versus recommended daily allowance vitamins during induction and maintenance intravesical treatment of nonmuscle invasive bladder cancer. J Urol, 184(5), 1915-9. PMID: 20846688.

Rosevear, H. M., Lightfoot, A. J., Nepple, K. G. & O'Donnell, M. A. (2010). Safety and efficacy of intravesical bacillus Calmette-Guérin plus interferon a-2b therapy for nonmuscle invasive bladder cancer in patients with prosthetic devices. J Urol, 184(5), 1920-4. PMID: 20846678.

Bockholt, N. A., Nepple, K. G., Powell, C. R. & Kreder, K. J. (2010). Traumatic urethral injury without pelvic fracture in an adult female. TheScientificWorldJournal, 10, 308-10. PMID: 20191243.

Nepple, K. G., O'Donnell, M. A. (2009). The optimal management of T1 high-grade bladder cancer. Can Urol Assoc J, 3(6 Suppl 4), S188-92. PMID: 20019983.

Nepple, K. G., Aubert, H. A., Braasch, M. R. & O'Donnell, M. A. (2009). Combination of BCG and interferon intravesical immunotherapy: an update. World J Urol, 27(3), 343-6. PMID: 19479263.

Nepple, K. G., Fallon, B. (2007). Indiana pouch stone formation caused by a long-forgotten metallic ball bearing. Can J Urol, 14(5), 3705-6. PMID: 17949527.