Kenneth G. Nepple, MD

Portrait
Clinical Associate Professor of Urology

Contact Information

Primary Office
3228 RCP
Iowa City, IA 52242
319-356-2421

Education

BS, Psychology, Iowa State University
MD, Medicine, University of Iowa
Resident, Urology, University of Iowa
Fellow, Urologic Oncology, Washington Unversity

Publications

Sherwood, B. G., Nepple, K. G. & Erickson, B. A. (2018). Managing the High Incidence of Testicular Pain and Pathology in Prisoners with Telemedicine. Urology Practice, 5(5), 372-376. DOI: 10.1016/j.urpr.2017.09.004.

Nepple, K. G. (2018). Editorial Comment. (Vols. 200). (2), pp. 300. Journal of Urology. DOI: 10.1016/j.juro.2018.03.144.

Sherwood, B. G., Han, Y., Nepple, K. G. & Erickson, B. A. (2018). Evaluating the Effectiveness, Efficiency and Safety of Telemedicine for Urological Care in the Male Prisoner Population. Urology Practice, 5(1), 44-51. DOI: 10.1016/j.urpr.2017.01.001.

Tobert, C. M., Mott, S. L. & Nepple, K. G. (2018). Malnutrition Diagnosis during Adult Inpatient Hospitalizations: Analysis of a Multi-Institutional Collaborative Database of Academic Medical Centers. Journal of the Academy of Nutrition and Dietetics, 118(1), 125-131. DOI: 10.1016/j.jand.2016.12.019.

Steinberg, R. L., Nepple, K. G., Velaer, K. N., Thomas, L. J. & O'Donnell, M. A. (2017). Quadruple immunotherapy of Bacillus Calmette-Guérin, interferon, interleukin-2, and granulocyte-macrophage colony-stimulating factor as salvage therapy for non–muscle-invasive bladder cancer. Urologic Oncology: Seminars and Original Investigations, 35(12), 670.e7-670.e14. DOI: 10.1016/j.urolonc.2017.07.024.

Bertrand, L. A., Thomas, L. J., Li, P., Buchta, C. M., Boi, S. K., Orlandella, R. M., Brown, J. A., Nepple, K. G. & Norian, L. A. (2017). Obesity as defined by waist circumference but not body mass index is associated with higher renal mass complexity. Urologic Oncology: Seminars and Original Investigations, 35(11), 661.e1-661.e6. DOI: 10.1016/j.urolonc.2017.06.058.

Tobert, C. M., Hamilton-Reeves, J. M., Norian, L. A., Hung, C., Brooks, N. A., Holzbeierlein, J. M., Downs, T. M., Robertson, D. P., Grossman, R. & Nepple, K. G. (2017). Emerging Impact of Malnutrition on Surgical Patients: Literature Review and Potential Implications for Cystectomy in Bladder Cancer. (Vols. 198). (3), pp. 511-519. Journal of Urology. DOI: 10.1016/j.juro.2017.01.087.

Swanton, A. R., Alzubaidi, A. N., Han, Y., Nepple, K. G. & Erickson, B. A. (2017). Trends in Operating Room Assistance for Major Urologic Surgical Procedures: An Increasing Role for Advanced Practice Providers. Urology, 106, 76-81. PMID: 28499759.

Uhlman, M. A., Gruca, T. S., Jarvie, C. A., Ghareeb, G. M., Morrison, P. G., Han, Y., Nepple, K. G. & Erickson, B. A. (2017). Taking the Procedure to the Patient: Increasing Access to Urological Procedural Care through Outreach. Urology Practice, 4(4), 335-341. DOI: 10.1016/j.urpr.2016.07.006.

Venur, V. A., Joshi, M., Nepple, K. G. & Zakharia, Y. (2017). Spotlight on nivolumab in the treatment of renal cell carcinoma: Design, development, and place in therapy. (Vols. 11). pp. 1175-1182. Drug Design, Development and Therapy. DOI: 10.2147/DDDT.S110209.

Erickson, B. A., Han, Y., Meeks, W., Gulig, S., Fang, R., Annam, K. & Nepple, K. G. (2017). Increasing Use of Advanced Practice Providers for Urological Office Procedural Care in the United States. Urology Practice, 4(2), 169-175. DOI: 10.1016/j.urpr.2016.04.006.

Steinberg, R. L., Thomas, L. J. & Nepple, K. G. (2016). Intravesical and alternative bladder-preservation therapies in the management of non-muscle-invasive bladder cancer unresponsive to bacillus Calmette-Guérin. Urologic oncology, 34(6), 279-89. PMID: 26777259.

Velaer, K. N., Steinberg, R. L., Thomas, L. J., O'Donnell, M. A. & Nepple, K. G. (2016). Experience with Sequential Intravesical Gemcitabine and Docetaxel as Salvage Therapy for Non-Muscle Invasive Bladder Cancer. Current urology reports, 17(5), 38. PMID: 26968418.

Moriarty, M. A., Nepple, K. G., Tracy, C. R., Strigenz, M. E., Lee, D. K. & Brown, J. A. (2016). Impact of Robotic Fellowship Experience on Perioperative Outcomes of Robotic-Assisted Laparoscopic Partial Nephrectomy. Current urology, 9(1), 19-23. PMID: 26989366.

Eggener, S. E., Badani, K., Barocas, D. A., Barrisford, G. W., Cheng, J. S., Chin, A. I., Corcoran, A., Epstein, J. I., George, A. K., Gupta, G. N., Hayn, M. H., Kauffman, E. C., Lane, B., Liss, M. A., Mirza, M., Morgan, T. M., Moses, K., Nepple, K. G., Preston, M. A., Rais-Bahrami, S., Resnick, M. J., Siddiqui, M. M., Silberstein, J., Singer, E. A., Sonn, G. A., Sprenkle, P., Stratton, K. L., Taylor, J., Tomaszewski, J., Tollefson, M., Vickers, A., White, W. M. & Lowrance, W. T. (2015). Gleason 6 Prostate Cancer: Translating Biology into Population Health. The Journal of urology, 194(3), 626-34. PMID: 25849602.

Shah, V. S., Jung, N. L., Lee, D. K. & Nepple, K. G. (2015). Does Routine Pathology Analysis of Adult Circumcision Tissue Identify Penile Cancer?. Urology, 85(6), 1431-4. PMID: 25872693.

Moriarty, M. A., Uhlman, M. A., Bing, M. T., O'Donnell, M. A., Brown, J. A., Tracy, C. R., Deorah, S., Nepple, K. G. & Gupta, A. (2015). Evaluating the safety of intraoperative instillation of intravesical chemotherapy at the time of nephroureterectomy. BMC urology, 15, 45. PMID: 26018765.

Krings, J. G., Kallogjeri, D., Wineland, A., Nepple, K. G., Piccirillo, J. F. & Getz, A. E. (2015). Complications following primary and revision transsphenoidal surgeries for pituitary tumors. Laryngoscope, 125(2), 311-317. DOI: 10.1002/lary.24892.

Nepple, K. G. (2015). Reply. (Vols. 85). (6), pp. 1435. Urology. DOI: 10.1016/j.urology.2014.12.070.

Steinberg, R. L., Thomas, L. J., O’Donnell, M. A. & Nepple, K. G. (2015). Sequential intravesical gemcitabine and docetaxel for the salvage treatment of non-muscle invasive bladder cancer. Bladder Cancer, 1(1), 65-72. DOI: 10.3233/BLC-150008.

Shah, V. S., Nepple, K. G. & Lee, D. K. (2014). Routine pathology evaluation of hydrocele and spermatocele specimens is associated with significant costs and no identifiable benefit. The Journal of urology, 192(4), 1179-82. PMID: 24768992.

Vemana, G., Nepple, K. G., Vetter, J., Sandhu, G. & Strope, S. A. (2014). Defining the potential of neoadjuvant chemotherapy use as a quality indicator for bladder cancer care. The Journal of urology, 192(1), 43-9. PMID: 24518776.

Moriarty, M. A., Dahmoush, L. & Nepple, K. G. (2014). IgG4 related disease of the ureter (inflammatory pseudotumor). The Journal of urology, 191(4), 1126-7. PMID: 24440497.

Nepple, K. G., Kibel, A. S. (2014). Reply to michael froehner's letter to the editor re: Kenneth G. Nepple, Andrew J. Stephenson, Dorina Kallogjeri, et al. Mortality after prostate cancer treatment with radical prostatectomy, external-beam radiation therapy, or brachytherapy in men without comorbidity. Eur Urol 2013;64:372-8. (Vols. 65). (3) European Urology. DOI: 10.1016/j.eururo.2013.11.036.

Ahmed, K., Khan, S. A., Hayn, M. H., Agarwal, P. K., Badani, K. K., Derya Balbay, M., Castle, E. P., Dasgupta, P., Ghavamian, R., Guru, K. A., Hemal, A. K., Hollenbeck, B. K., Kibel, A. S., Menon, M., Mottrie, A., Nepple, K., Pattaras, J. G., Peabody, J. O., Poulakis, V., Pruthi, R. S., Redorta, J. P., Rha, K. H., Richstone, L., Saar, M., Scherr, D. S., Siemer, S., Stoeckle, M., Wallen, E. M., Weizer, A. Z., Wiklund, P., Wilson, T., Woods, M. & Khan, M. S. (2014). Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: Results from the international robotic cystectomy consortium. European Urology, 65(2), 340-347. DOI: 10.1016/j.eururo.2013.09.042.

Hadj-Moussa, M., Nepple, K. G. & Brown, J. A. (2014). Comparison of a single center, academic surgeon real-world experience with three percutaneous nephrolithotomy lithotripters. Canadian Journal of Urology, 21(5), 7470-7474.

Krings, J. G., Kallogjeri, D., Wineland, A., Nepple, K. G., Piccirillo, J. F. & Getz, A. E. (2014). Complications of primary and revision functional endoscopic sinus surgery for chronic rhinosinusitis. Laryngoscope, 124(4), 838-845. DOI: 10.1002/lary.24401.

Al-Daghmin, A., Kauffman, E. C., Shi, Y., Badani, K., Balbay, M. D., Canda, E., Dasgupta, P., Ghavamian, R., Grubb, R., Hemal, A., Kaouk, J., Kibel, A. S., Maatman, T., Menon, M., Mottrie, A., Nepple, K., Pattaras, J. G., Peabody, J. O., Poulakis, V., Pruthi, R., Palou Redorta, J., Rha, K. H., Richstone, L., Schanne, F., Scherr, D. S., Siemer, S., Stöckle, M., Wallen, E. M., Weizer, A., Wiklund, P., Wilson, T., Wilding, G., Woods, M. & Guru, K. A. (2014). Efficacy of robot-assisted radical cystectomy (RARC) in advanced bladder cancer: Results from the International Radical Cystectomy Consortium (IRCC). BJU International, 114(1), 98-103. DOI: 10.1111/bju.12569.

Lubaroff, D. M., Vaena, D., Brown, J. A., Zehr, P., Griffith, K. C., Brown, E., Eastman, J., Nepple, K., Kattula, A. & Williams, R. D. (2014). Vaccine immunotherapy for prostate cancer: From mice to men. Immunologic Research, 59(1-3), 229-235. DOI: 10.1007/s12026-014-8531-2.

Bockholt, N. A., DeRoo, E. M., Nepple, K. G., Modrick, J. M., Smith, M. C., Fallon, B., Hass, A. C., Tracy, C. R. & Brown, J. A. (2013). First 100 cases at a low volume prostate brachytherapy institution: learning curve and the importance of continuous quality improvement. The Canadian journal of urology, 20(5), 6907-12. PMID: 24128827.

Bockholt, N. A., DeRoo, E. M., Nepple, K. G., Modrick, J. M., Smith, M. C., Fallon, B., Hass, A. C., Tracy, C. R. & Brown, J. A. (2013). First 100 cases at a low volume prostate brachytherapy institution: Learning curve and the importance of continuous quality improvement. Canadian Journal of Urology, 20(5), 6907-6912.

Nepple, K. G., Stephenson, A. J., Kallogjeri, D., Michalski, J., Grubb, R. L., Strope, S. A., Haslag-Minoff, J., Piccirillo, J. F., Ciezki, J. P., Klein, E. A., Reddy, C. A., Yu, C., Kattan, M. W. & Kibel, A. S. (2013). Mortality after prostate cancer treatment with radical prostatectomy, external-beam radiation therapy, or brachytherapy in men without comorbidity. European Urology, 64(3), 372-378. DOI: 10.1016/j.eururo.2013.03.005.

Nepple, K. G., Strope, S. A., Grubb, 3rd, R. L. & Kibel, A. S. (2013). Early oncologic outcomes of robotic vs. open radical cystectomy for urothelial cancer. Urologic oncology, 31(6), 894-8. PMID: 21803615.

Johar, R. S., Hayn, M. H., Stegemann, A. P., Ahmed, K., Agarwal, P., Balbay, M. D., Hemal, A., Kibel, A. S., Muhletaler, F., Nepple, K., Pattaras, J. G., Peabody, J. O., Palou Redorta, J., Rha, K. H., Richstone, L., Saar, M., Schanne, F., Scherr, D. S., Siemer, S., Stökle, M., Weizer, A., Wiklund, P., Wilson, T., Woods, M., Yuh, B. & Guru, K. A. (2013). Complications after robot-assisted radical cystectomy: Results from the international robotic cystectomy consortium. European Urology, 64(1), 52-57. DOI: 10.1016/j.eururo.2013.01.010.

Nepple, K. G., Rosevear, H. M., Stolpen, A. H., Brown, J. A. & Williams, R. D. (2013). Concordance of preoperative prostate endorectal MRI with subsequent prostatectomy specimen in high-risk prostate cancer patients. Urologic Oncology: Seminars and Original Investigations, 31(5), 601-606. DOI: 10.1016/j.urolonc.2011.05.004.

Guru, K. A., Peabody, J. O., Ahmed, K., Kibel, A., Weizer, A., Hayn, M., Johar, R., Agarwal, P., Balbay, M., Hemal, A., Muhletaler, F., Nepple, K., Pattaras, J., Redorta, J., Rha, K. H., Richstone, L., Saar, M., Schanne, F., Scherr, D., Siemer, S., Stoekle, M., Wilson, T., Woods, M., Yuh, B. & Wiklund, P. (2013). Reply from Authors re: Manfred P. Wirth, Johannes Huber. What really matters is rarely measured: Outcome of routine care and patient-reported outcomes. Eur Urol 2013;64:58-9: Robot-assisted Versus Open Radical Cystectomy: Beating a Dead Horse. (Vols. 64). (1), pp. 60-61. European Urology. DOI: 10.1016/j.eururo.2013.02.034.

Marshall, S. J., Hayn, M. H., Stegemann, A. P., Agarwal, P. K., Badani, K. K., Balbay, M. D., Dasgupta, P., Hemal, A. K., Hollenbeck, B. K., Kibel, A. S., Menon, M., Mottrie, A., Nepple, K., Pattaras, J. G., Peabody, J. O., Poulakis, V., Pruthi, R. S., Palou Redorta, J., Rha, K. H., Richstone, L., Schanne, F., Scherr, D. S., Siemer, S., Stöckle, M., Wallen, E. M., Weizer, A. Z., Wiklund, P., Wilson, T., Woods, M. & Guru, K. A. (2013). Impact of surgeon and volume on extended lymphadenectomy at the time of robot-assisted radical cystectomy: Results from the International Robotic Cystectomy Consortium (IRCC). BJU International, 111(7), 1075-1080. DOI: 10.1111/j.1464-410X.2012.11583.x.

Sandhu, G. S., Nepple, K. G., Tanagho, Y. S. & Andriole, G. L. (2013). Prostate cancer chemoprevention. Seminars in Oncology, 40(3), 276-285. DOI: 10.1053/j.seminoncol.2013.04.003.

Haseebuddin, M., Dehdashti, F., Siegel, B. A., Liu, J., Roth, E. B., Nepple, K. G., Siegel, C. L., Fischer, K. C., Kibel, A. S., Andriole, G. L. & Miller, T. R. (2013). 11C-acetate PET/CT before radical prostatectomy: Nodal staging and treatment failure prediction. Journal of Nuclear Medicine, 54(5), 699-706. DOI: 10.2967/jnumed.112.111153.

Johnson, M. H., Nepple, K. G., Peck, V., Trinkaus, K., Klim, A., Sandhu, G. S. & Kibel, A. S. (2013). Randomized controlled trial of oxybutynin extended release versus placebo for urinary symptoms during intravesical Bacillus Calmette-Guérin treatment. The Journal of urology, 189(4), 1268-74. PMID: 23123375.

Nepple, K. G., Kallogjeri, D. & Bhayani, S. B. (2013). Benchtop evaluation of pressure barrier insufflator and standard insufflator systems. Surgical endoscopy, 27(1), 333-8. PMID: 22833262.

Sandhu, G. S., Nepple, K. G., Tanagho, Y. S. & Andriole, G. L. (2013). Laparoscopic prostatectomy for prostate cancer: continued role in urology. Surg Oncol Clin North Am, 22, 125-41.

Nepple, K. G., Andriole, G. L. (2013). Defining the problem. In Prostate Cancer Diagnosis: PSA, Biopsy and Beyond. pp. 1-10. DOI: 10.1007/978-1-62703-188-2_1.

Nepple, K. G., Sandhu, G. S. & Kibel, A. S. (2013). Percent free PSA. In Prostate Cancer Diagnosis: PSA, Biopsy and Beyond. pp. 51-60. DOI: 10.1007/978-1-62703-188-2_5.

Nepple, K. G., Kibel, A. S. & Andriole, G. L. (2013). Prostate cancer risk reduction by chemoprevention. In Management of Prostate Cancer: Third Edition. pp. 143-152. DOI: 10.1007/978-1-60761-259-9_9.

Johnson, M. H., Nepple, K. G. & Humphrey, P. A. (2012). Bladder lymphoma. J Urol, 188, 269-70.

Nepple, K. G., Sandhu, G. S., Rogers, C. R., Allaf, M. E., Kaouk, J. H., Figenshau, R. S., Stifelman, M. D. & Bhayani, S. B. (2012). Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy. Patient Saf Surg, 6, 8.

Nepple, K. G., Yang, L., Grubb, III, R. L. & Strope, S. A. (2012). Population based analysis of the increasing incidence of kidney cancer in the United States: evaluation of age specific trends from 1975 to 2006. J Urol, 187, 32-8.

Strope, S. A., Yang, L., Nepple, K. G., Andriole, G. L. & Owens, P. L. (2012). Population based comparative effectiveness of transurethral resection of the prostate and laser therapy for benign prostatic hyperplasia. J Urol, 187, 1341-5.

Kyllo, R. L., Tanagho, Y. S., Kaouk, J. H., Stifelman, M. D., Rogers, C. G., Hilyer, S. P., Sukumar, S. S., Nepple, K. G. & Bhayani, S. B. (2012). Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma. BMC Urol, 12, 11.

Nepple, K. G., Andriole, G. L. (2012). Prostate cancer chemoprevention with 5a-reductase inhibitors. (Vols. 30). pp. 553-4. Urol Oncol.

Tanagho, Y. S., Bhayani, S. B., Sandhu, G. S., Vaughn, N. P., Nepple, K. G. & Figenshau, R. S. (2012). Renal functional and perioperative outcomes of off-clamp versus clamped robot-assisted partial nephrectomy: matched cohort study. Urology, 80, 838-43.

Lightfoot, A. J., Rosevear, H. M., Nepple, K. G. & O'Donnell, M. A. (2012). Role of routine transurethral biopsy and isolated upper tract cytology after intravesical treatment of high-grade non-muscle invasive bladder cancer. Int J Urol, 19, 988-93.

Rosevear, H. M., Lightfoot, A. J., Birusingh, K. K., Maymí, J. L., Nepple, K. G. & O'Donnell, M. A. (2011). Factors affecting response to bacillus Calmette-Guérin plus interferon for urothelial carcinoma in situ. J Urol, 186(3), 817-23. PMID: 21788050.

Rosevear, H. M., Lightfoot, A. J., Nepple, K. G. & O'Donnell, M. A. (2011). Usefulness of the Spanish Urological Club for Oncological Treatment scoring model to predict nonmuscle invasive bladder cancer recurrence in patients treated with intravesical bacillus Calmette-Guérin plus interferon-a. J Urol, 185(1), 67-71. PMID: 21074202.

Nepple, K. G., Lightfoot, A. J., Rosevear, H. M., O'Donnell, M. A. & Lamm, D. L. (2010). Bacillus Calmette-Guérin with or without interferon a-2b and megadose versus recommended daily allowance vitamins during induction and maintenance intravesical treatment of nonmuscle invasive bladder cancer. J Urol, 184(5), 1915-9. PMID: 20846688.

Rosevear, H. M., Lightfoot, A. J., Nepple, K. G. & O'Donnell, M. A. (2010). Safety and efficacy of intravesical bacillus Calmette-Guérin plus interferon a-2b therapy for nonmuscle invasive bladder cancer in patients with prosthetic devices. J Urol, 184(5), 1920-4. PMID: 20846678.

Bockholt, N. A., Nepple, K. G., Powell, C. R. & Kreder, K. J. (2010). Traumatic urethral injury without pelvic fracture in an adult female. TheScientificWorldJournal, 10, 308-10. PMID: 20191243.

Nepple, K. G., O'Donnell, M. A. (2009). The optimal management of T1 high-grade bladder cancer. Can Urol Assoc J, 3(6 Suppl 4), S188-92. PMID: 20019983.

Nepple, K. G., Aubert, H. A., Braasch, M. R. & O'Donnell, M. A. (2009). Combination of BCG and interferon intravesical immunotherapy: an update. World J Urol, 27(3), 343-6. PMID: 19479263.

Nepple, K. G., Fallon, B. (2007). Indiana pouch stone formation caused by a long-forgotten metallic ball bearing. Can J Urol, 14(5), 3705-6. PMID: 17949527.