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Vignesh T. Packiam

Clinical Assistant Professor of Urology

Contact Information

3226 Carver Pavilion (RCP)
200 Hawkins Drive
Iowa City, IA 52242


BS, Biology, Philosophy, University of Wisconsin-Madison
MD, University of Pittsburgh School of Medicine
Resident, Urology, University of Chicago Medical Center
Fellow, Urologic Oncology, Mayo Clinic


Sharma, V., Wymer, K. M., Borah, B. J., Saigal, C. S., Litwin, M. S., Packiam, V. T., Thompson, R. H., Tollefson, M. K., Karnes, R. J. & Boorjian, S. A. (2020). Cost-Effectiveness of Maintenance bacillus Calmette-Guérin for Intermediate and High Risk Nonmuscle Invasive Bladder Cancer. The Journal of urology, 204(3), 442-449. PMID: 32191580.

Labbate, C. V., Werntz, R. P., Galansky, L. B., Packiam, V. T. & Eggener, S. E. (2020). National management trends in clinical stage IIA nonseminomatous germ cell tumor (NSGCT) and opportunities to avoid dual therapy. Urologic oncology, 38(8), 687.e13-687.e18. PMID: 32305267.

Liauw, S. L., Ham, S. A., Das, L. C., Rudra, S., Packiam, V. T., Koshy, M., Weichselbaum, R. R., Becker, Y. T., Bodzin, A. S. & Eggener, S. E. (2020). Prostate Cancer Outcomes Following Solid-Organ Transplantation: A SEER-Medicare Analysis. Journal of the National Cancer Institute, 112(8), 847-854. PMID: 31728517.

Packiam, V. T., Tsivian, M., Avulova, S., Sharma, V., Tarrell, R., Cheville, J. C., Frank, I., Thompson, R. H., Tollefson, M. K., Gettman, M. T., Karnes, R. J., Thapa, P. & Boorjian, S. A. (2020). Long-term outcomes of incidental prostate cancer at radical cystectomy. Urologic oncology. PMID: 32624422.

Williams, S. B., Cumberbatch MGK,, Kamat, A. M., Jubber, I., Kerr, P. S., McGrath, J. S., Djaladat, H., Collins, J. W., Packiam, V. T., Steinberg, G. D., Lee, E., Kassouf, W., Black, P. C., Cerantola, Y., Catto JWF, & Daneshmand, S. (2020). Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis. European urology. PMID: 32624275.

Packiam, V. T., Tsivian, M., Lohse, C. M., Cheville, J. C., Boorjian, S. A., Houston Thompson, R. & Leibovich, B. C. (2020). Simultaneous versus staged partial nephrectomies for bilateral synchronous solid renal masses. Urologic oncology, 38(7), 640.e13-640.e22. PMID: 32402769.

Packiam, V. T., Barocas, D. A. & Boorjian, S. A. (2020). Microscopic Hematuria: Diagnosis Is Only Half the Battle. (Vols. 77). (5), pp. 599-600. European urology. PMID: 31870514.

Werntz, R. P., Smith, Z. L., Packiam, V. T., Smith, N. & Steinberg, G. D. (2020). The Impact of Lymphovascular Invasion on Risk of Upstaging and Lymph Node Metastasis at the Time of Radical Cystectomy. European urology focus, 6(2), 292-297. PMID: 30297221.

Packiam, V. T., Tyson, Ii, M. D., Tsivian, M., Lohse, C. M., Boorjian, S. A., Cheville, J. C., Costello, B. A., Leibovich, B. C. & Thompson, R. H. (2020). The association of anxiety and depression with perioperative and oncologic outcomes among patients with clear cell renal cell carcinoma undergoing nephrectomy. Urologic oncology, 38(2), 41.e19-41.e27. PMID: 31761613.

Joseph, J. P., Potretzke, T. A., Packiam, V., Sharma, V., Toussi, A., Miest, T. S., Juvet, T., Boorjian, S. A., Thompson, R. H., Welle, C. L., Atwell, T. D., Leibovich, B. C., Tollefson, M. K. & Potretzke, A. M. (2020). Percutaneous Image-guided Core Needle Biopsy for Upper Tract Urothelial Carcinoma. UROLOGY, 135, 95-100. DOI: 10.1016/j.urology.2019.10.005.

Packiam, V. T., Patel, S., Werntz, R., Steinberg, G. (In Press). Urinary Stomas: Disease States that Lead to the Creation of a Urinary Stoma and the Use of Intestinal Segments in Urinary Diversion. In WOCN Ostomy Management. (2e), pp. 471-486. London: Springer.

Packiam, V., Boorjian, S. (In Press). Partial Cystectomy. Critical Element 1: Localization of tumor including issues specific to diverticulum, urachal tumors, paraganglioma. In OSCS. London: Springer.

Packiam, V. T., Thompson, R. H. (2019). The limits of complex partial nephrectomy: are there any?. (Vols. 7). (Suppl 8), pp. S345. Annals of translational medicine. PMID: 32016063.

Packiam, V. T., Werntz, R. P. & Steinberg, G. D. (2019). Current Clinical Trials in Non-muscle-Invasive Bladder Cancer: Heightened Need in an Era of Chronic BCG Shortage. Current urology reports, 20(12), 84. PMID: 31781942.

Siddiqui, N. Y., Helfand, B. T., Andreev, V. P., Kowalski, J. T., Bradley, M. S., Lai, H. H., Berger, M. B., Mueller, M. G., Bickhaus, J. A., Packiam, V. T., Fenner, D., Gillispie, B. W. & Kirkali, Z. (2019). Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses. The Journal of urology, 202(5), 880-889. PMID: 30925127.

Tsivian, M., Packiam, V. T. & Thompson, R. H. (2019). Tumor Enucleation is Appropriate During Partial Nephrectomy: Against. European urology focus, 5(6), 925-926. PMID: 30910392.

Packiam, V. T., Pariser, J. J. (2019). Association between perioperative morbidity and mortality after radical cystectomy: an opportunity to understand the complication snowball effect. (Vols. 8). (Suppl 3), pp. S261-S262. Translational andrology and urology. PMID: 31392139.

Barashi, N. S., Pearce, S. M., Cohen, A. J., Pariser, J. J., Packiam, V. T. & Eggener, S. E. (2018). Incidence, Risk Factors, and Outcomes for Rectal Injury During Radical Prostatectomy: A Population-based Study. European urology oncology, 1(6), 501-506. PMID: 31158094.

Werntz, R. P., Riedinger, C. B., Fantus, R. J., Smith, Z. L., Packiam, V. T., Adamsky, M. A., Smith, N. & Steinberg, G. D. (2018). The role of inguinal lymph node dissection in men with urethral squamous cell carcinoma. Urologic oncology, 36(12), 526.e1-526.e6. PMID: 30446445.

Packiam, V. T., Lamm, D. L., Barocas, D. A., Trainer, A., Fand, B., Davis, 3rd, R. L., Clark, W., Kroeger, M., Dumbadze, I., Chamie, K., Kader, A. K., Curran, D., Gutheil, J., Kuan, A., Yeung, A. W. & Steinberg, G. D. (2018). An open label, single-arm, phase II multicenter study of the safety and efficacy of CG0070 oncolytic vector regimen in patients with BCG-unresponsive non-muscle-invasive bladder cancer: Interim results. Urologic oncology, 36(10), 440-447. PMID: 28755959.

Golan S, S., Packiam, V. & Shalhav, A. (2018). Robotic Radical Prostatectomy: Margins Positivity and Implications of Cancer Control. In A. K. Hemal , M. Menon (Eds.) Robotics in Genitourinary Surgery. (2e), pp. 471-486. London: Springer.

Packiam, V. T., Nottingham, C. U., Cohen, A. J., Eggener, S. E. & Gerber, G. S. (2018). No Effect of Music on Anxiety and Pain During Transrectal Prostate Biopsies: A Randomized Trial. Urology, 117, 31-35. PMID: 29709434.

Fantus, R. J., Packiam, V. T., Wang, C. H., Erickson, B. A. & Helfand, B. T. (2018). The Relationship between Sleep Disorders and Lower Urinary Tract Symptoms: Results from the NHANES. The Journal of urology, 200(1), 161-166. PMID: 29408214.

Barashi, N. S., Rodriguez, M. V., Packiam, V. T. & Gundeti, M. S. (2018). Bladder Reconstruction with Bowel: Robot-Assisted Laparoscopic Ileocystoplasty with Mitrofanoff Appendicovesicostomy in Pediatric Patients. Journal of endourology, 32(S1), S119-S126. PMID: 29774817.

Packiam, V. T., Barashi, N. S. & Shalhav, A. L. (2018). Robot-Assisted Laparoscopic Adrenalectomy. Journal of endourology, 32(S1), S82-S87. PMID: 29774815.

Packiam, V. T., Pariser, J. J. (2018). Ongoing efforts to reduce perioperative morbidity of radical cystectomy: towards widespread adoption of extended-duration thromboprophylaxis. (Vols. 7). (Suppl 1), pp. S81-S82. Translational andrology and urology. PMID: 29645005.

Packiam, V. T., Eggener, S. E. (2017). Minimal difference in survival between radical prostatectomy and observation in men with modest life expectancy. Evidence-based medicine, 22(6), 222. PMID: 29127213.

Chen, H., Na, R., Packiam, V. T., Conran, C. A., Jiang, D., Tao, S., Yu, H., Lin, X., Meng, W., Zheng, S. L., Brendler, C. B., Helfand, B. T. & Xu, J. (2017). Reclassification of prostate cancer risk using sequentially identified SNPs: Results from the REDUCE trial. The Prostate, 77(11), 1179-1186. PMID: 28670847.

Tallman, J. E., Packiam, V. T., Wroblewski, K. E., Paner, G. P. & Eggener, S. E. (2017). Influence of pathologist experience on positive surgical margins following radical prostatectomy. Urologic oncology, 35(7), 461.e1-461.e6. PMID: 28302349.

Rodriguez, J. F., Packiam, V. T., Boysen, W. R., Johnson, S. C., Smith, Z. L., Smith, N. D., Shalhav, A. L. & Steinberg, G. D. (2017). Utilization and Outcomes of Nephroureterectomy for Upper Tract Urothelial Carcinoma by Surgical Approach. Journal of endourology, 31(7), 661-665. PMID: 28537436.

Schadler, E. S., Packiam, V. & Gundeti, M. (2017). Robotic-Assisted Laparoscopic Mitrofanoff Appendicovesicostomy (RALMA). In V. R. Patel , M. Ramalingam (Eds.) Operative Atlas of Laparoscopic Reconstructive Urology. (2e), pp. 469-482. New Delhi: Springer-Verlag London.

Packiam, V. T., Agrawal, V. A., Pariser, J. J., Cohen, A. J., Nottingham, C. U., Pearce, S. M., Smith, N. D. & Steinberg, G. D. (2017). Redefining the implications of nasogastric tube placement following radical cystectomy in the alvimopan era. World journal of urology, 35(4), 625-631. PMID: 27476163.

Packiam, V. T., Agrawal, V. A., Cohen, A. J., Pariser, J. J., Johnson, S. C., Bales, G. T., Smith, N. D. & Steinberg, G. D. (2017). Lessons from 151 ureteral reimplantations for postcystectomy ureteroenteric strictures: A single-center experience over a decade. Urologic oncology, 35(3), 112.e19-112.e25. PMID: 27825514.

Pariser, J. J., Pearce, S. M., Anderson, B. B., Packiam, V. T., Prachand, V. N., Smith, N. D. & Steinberg, G. D. (2017). Extended Duration Enoxaparin Decreases the Rate of Venous Thromboembolic Events after Radical Cystectomy Compared to Inpatient Only Subcutaneous Heparin. The Journal of urology, 197(2), 302-307. PMID: 27569434.

Packiam, V. T., Johnson, S. C. & Steinberg, G. D. (2017). Non-muscle-invasive bladder cancer: Intravesical treatments beyond Bacille Calmette-Guérin. Cancer, 123(3), 390-400. PMID: 28112819.

Johnson, S. C., Packiam, V. T., Golan, S., Cohen, A. J., Nottingham, C. U. & Smith, N. D. (2017). The Effect of Obesity on Perioperative Outcomes for Open and Minimally Invasive Prostatectomy. Urology, 100, 111-116. PMID: 27890683.

Nottingham, C. U., Cohen, A. J., Packiam, V. T., Pariser, J. J. & Gerber, G. S. (2017). Hospital-Based Analysis of Trends and Outcomes for Patients Undergoing Pyelolithotomy. Journal of endourology, 31(1), 78-84. PMID: 27784168.

Na, R., Ye, D., Qi, J., Liu, F., Helfand, B. T., Brendler, C. B., Conran, C. A., Packiam, V., Gong, J., Wu, Y., Zheng, S. L., Mo, Z., Ding, Q., Sun, Y. & Xu, J. (2017). Prostate health index significantly reduced unnecessary prostate biopsies in patients with PSA 2-10 ng/mL and PSA > 10 ng/mL: Results from a Multicenter Study in China. PROSTATE, 77(11), 1221-1229. DOI: 10.1002/pros.23382.

Cohen, A. J., Packiam, V., Nottingham, C., Steinberg, G., Smith, N. D. & Patel, S. (2017). Upstaging of nonurothelial histology in bladder cancer at the time of surgical treatment in the National Cancer Data Base. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 35(1). DOI: 10.1016/j.urolonc.2016.08.002.

Packiam, V. T., Cohen, A. J., Pariser, J. J., Nottingham, C. U., Faris, S. F. & Bales, G. T. (2016). The Impact of Minimally Invasive Surgery on Major Iatrogenic Ureteral Injury and Subsequent Ureteral Repair During Hysterectomy: A National Analysis of Risk Factors and Outcomes. Urology, 98, 183-188. PMID: 27392649.

Packiam, V., Hatcher, D., Shalhav, A. (2016). Robotic, Laparoscopic, and Open Approaches to the Adrenal Gland (Benign). In J. Smith , S. Howards , G. Preminger & R. Dmochowski (Eds.) Hinman’s Atlas of Urologic Surgery. (4e) Philadelphia: Elsevier.

Cohen, A. J., Packiam, V. T., Nottingham, C. U., Pariser, J. J., Faris, S. F. & Bales, G. T. (2016). Iatrogenic Bladder Injury: National Analysis of 30-Day Outcomes. Urology, 97, 250-256. PMID: 27181242.

Packiam, V. T., Cohen, A. J., Pariser, J. J. & Bales, G. T. (2016). Reply by the Authors. (Vols. 97). pp. 281. Urology. PMID: 27562201.

Cohen, A. J., Packiam, V. T., Nottingham, C. U., Alberts, B. D., Faris, S. F. & Bales, G. T. (2016). 30-Day Morbidity and Reoperation Following Midurethral Sling: Analysis of 8772 Cases Using a National Prospective Database. Urology, 95, 72-9. PMID: 27196030.

Cohen, A. J., Packiam, V. T. & Bales, G. T. (2016). Author Reply. (Vols. 95). pp. 78-9. Urology. PMID: 27396832.

Packiam, V. T., Nottingham, C. U., Cohen, A. J., Pearce, S. M., Shalhav, A. L. & Eggener, S. E. (2016). The Impact of Perioperative Aspirin on Bleeding Complications Following Robotic Partial Nephrectomy. Journal of endourology, 30(9), 997-1003. PMID: 27338841.

Packiam, V. T., Cohen, A. J., Nottingham, C. U., Pariser, J. J., Faris, S. F. & Bales, G. T. (2016). Open Vs Minimally Invasive Adult Ureteral Reimplantation: Analysis of 30-day Outcomes in the National Surgical Quality Improvement Program (NSQIP) Database. Urology, 94, 123-8. PMID: 27210571.

Pariser, J. J., Packiam, V. T., Adamsky, M. A. & Bales, G. T. (2016). Trends in Simple Prostatectomy for Benign Prostatic Hyperplasia. Current urology reports, 17(8), 57. PMID: 27294802.

Packiam, V. T., Pearce, S. M. & Steinberg, G. D. (2016). The role of mycobacterial cell wall nucleic acid complex in the treatment of bacillus Calmette-Guérin failures for non-muscle-invasive bladder cancer. Therapeutic advances in urology, 8(1), 29-37. PMID: 26834838.

Cohen, A., Nottingham, C., Packiam, V., Jaskowiak, N. & Gundeti, M. (2016). Attitudes and knowledge of urethral catheters: a targeted educational intervention. BJU INTERNATIONAL, 118(4), 654-659. DOI: 10.1111/bju.13506.

Packiam, V. T., Cohen, A. J., Pariser, J. J. & Bales, G. T. (2016). Re: Packiam et al: The Impact of Minimally Invasive Surgery on Major Iatrogenic Ureteral Injury and Subsequent Ureteral Repair During Hysterectomy: A National Analysis of Risk Factors and Outcome (Urology 2016; doi: 10.1016/j.urology.2016.06.041) Reply. (Vols. 97). pp. 281-281. UROLOGY.

Packiam, V. T., Patel, S. G., Pariser, J. J., Richards, K. A., Weiner, A. B., Paner, G. P., VanderWeele, D. J., Zagaja, G. P. & Eggener, S. E. (2015). Contemporary Population-Based Comparison of Localized Ductal Adenocarcinoma and High-Risk Acinar Adenocarcinoma of the Prostate. Urology, 86(4), 777-82. PMID: 26196240.

Pariser, J. J., Pearce, S. M., Patel, S. G., Anderson, B. B., Packiam, V. T., Shalhav, A. L., Bales, G. T. & Smith, N. D. (2015). Rhabdomyolysis After Major Urologic Surgery: Epidemiology, Risk Factors, and Outcomes. Urology, 85(6), 1328-32. PMID: 26099878.

Pariser, J. J., Pearce, S. M., Patel, S. G., Packiam, V. T., Anderson, B. B., Shalhav, A. L., Bales, G. T. & Smith, N. D. (2015). RHABDOMYOLYSIS AFTER MAJOR UROLOGIC SURGERY: INCIDENCE, RISK FACTORS AND OUTCOMES. (Vols. 193). (4), pp. E343-E343. JOURNAL OF UROLOGY.

Tohme, S., Geller, D. A., Cardinal, J. S., Chen, H., Packiam, V., Reddy, S., Steel, J., Marsh, J. W. & Tsung, A. (2013). Radiofrequency ablation compared to resection in early-stage hepatocellular carcinoma. HPB, 15(3), 210-217. DOI: 10.1111/j.1477-2574.2012.00541.x.

Packiam, V., Bartlett, D. L., Tohme, S., Reddy, S., Marsh, J. W., Geller, D. A. & Tsung, A. (2012). Minimally Invasive Liver Resection: Robotic Versus Laparoscopic Left Lateral Sectionectomy. JOURNAL OF GASTROINTESTINAL SURGERY, 16(12), 2233-2238. DOI: 10.1007/s11605-012-2040-1.

Kitisin, K., Packiam, V., Bartlett, D. L. & Tsung, A. (2011). A current update on the evolution of robotic liver surgery. Minerva chirurgica, 66(4), 281-93. PMID: 21873962.

Sumpter, T. L., Packiam, V., Turnquist, H. R., Castellaneta, A., Yoshida, O. & Thomson, A. W. (2011). DAP12 Promotes IRAK-M Expression and IL-10 Production by Liver Myeloid Dendritic Cells and Restrains Their T Cell Allostimulatory Ability. JOURNAL OF IMMUNOLOGY, 186(4), 1970-1980. DOI: 10.4049/jimmunol.1000527.

Kitisin, K., Packiam, V., Steel, J., Humar, A., Gamblin, T. C., Geller, D. A., Marsh, J. W. & Tsung, A. (2011). Presentation and outcomes of hepatocellular carcinoma patients at a western centre. HPB, 13(10), 712-722. DOI: 10.1111/j.1477-2574.2011.00362.x.