Stephen Russell, MD

Contact Information

Office: 11196I PFP
Phone: 319-356-4588
Faculty Profile

Brief description of current research:

My current research focuses on evaluating treatments for retinal disorders, typically through clinical trials. I am currently investigating gene replacement therapy to treat Leber's congenital amaurosis, as well as evaluating a light cycle inhibitor to treat the atrophic form of age-related macular degeneration termed geographic atrophy.

3 most influential diabetes/obesity/metabolism publications:

  • Abramoff M, Folk J, Han D, Walker J, Williams D, Russell S, Massin P, Cochener B, Gain P, Tang L, Lamard M, Moga D, Quellec G, Niemeijer M. Automated analysis of retinal images for detection of referable diabetic retinopathy. JAMA Ophthalmol. 2013 March 1. 131(3):351-7.
  • Klyce SD, Russell SR. Numerical solution of coupled transport equations applied to corneal hydration dynamics. J Physiol. 1979 Jul;292:107-34.
  • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI, Hageman JL, Stockman HA, Borchardt JD, Gehrs KM, Smith RJ, Silvestri G, Russell SR, Klaver CC, Barbazetto I, Chang S, Yannuzzi LA, Barile GR, Merriam JC, Smith RT, Olsh AK, Bergeron J, Zernant J, Merriam JE, Gold B, Dean M, Allikmets R. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7227-32. Epub 2005 May 3.


I have been PI an otherwise involved in a number of clinical trial for treating diabetic retinopathy and in Dr. Abramoff’s research analyzing retinal images.