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Recent Research Publications

September 16-30, 2022

Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules. Parchure A, Tian M, Stalder D, Boyer CK, Bearrows SC, Rohli KE, Zhang J, Rivera-Molina F, Ramazanov BR, Mahata SK, Wang Y, Stephens SB, Gershlick DC, von Blume J. J Cell Biol. 2022 Dec 5;221(12):e202206132. doi: 10.1083/jcb.202206132. Epub 2022 Sep 29. PMID: 36173346

The Rapid Reduction of Infection-Related Visits and Antibiotic Use Among People With Cystic Fibrosis After Starting Elexacaftor-Tezacaftor-Ivacaftor. Miller AC, Harris LM, Cavanaugh JE, Abou Alaiwa M, Stoltz DA, Hornick DB, Polgreen PM. Clin Infect Dis. 2022 Sep 30;75(7):1115-1122. doi: 10.1093/cid/ciac117. PMID: 35142340

Ninety-Day Risk-Standardized Home Time as a Performance Metric for Cardiac Surgery Hospitals in the United States. Mentias A, Desai MY, Keshvani N, Gillinov AM, Johnston D, Kumbhani DJ, Hirji SA, Sarrazin MV, Saad M, Peterson ED, Mack MJ, Cram P, Girotra S, Kapadia S, Svensson L, Pandey A. Circulation. 2022 Sep 26:101161CIRCULATIONAHA122059496. doi: 10.1161/CIRCULATIONAHA.122.059496. Online ahead of print. PMID: 36154237

Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction. Yu W, Moninger TO, Rector MV, Stoltz DA, Welsh MJ. Dev Cell. 2022 Sep 26;57(18):2221-2236.e5. doi: 10.1016/j.devcel.2022.08.010. Epub 2022 Sep 14.

PMID: 36108628

Pelvic and central nervous system tuberculosis complicated by a paradoxical response manifesting as a spinal tuberculoma: a case report. Zandvakili A, Kobayashi T, Kaewpoowat Q, Parsons MG, Ford B, Barker JH, Johnson M. BMC Infect Dis. 2022 Sep 24;22(1):750. doi: 10.1186/s12879-022-07731-6. PMID: 36153478

Sleep, circadian rhythm characteristics and melatonin levels in later life adults with and without coronary artery disease. Moon C, Benson CJ, Albashayreh A, Perkhounkova Y, Burgess HJ. J Clin Sleep Med. 2022 Sep 23. doi: 10.5664/jcsm.10308. Online ahead of print. PMID: 36148612

Colostomy as a definitive treatment in an ALS patient with acute colonic Pseudo-obstruction refractory to medical management, a case report. Liu G, Hrabe J, Sanchez R. BMC Neurol. 2022 Sep 22;22(1):366. doi: 10.1186/s12883-022-02893-x. PMID: 36138349

Decreased outflow facility and Schlemm's canal defects in a mouse model of glaucoma. Mavlyutov TA, Kuhn MS, Bilal SE, De Ieso ML, Chauhan AK, Stamer WD, McDowell CM. Exp Eye Res. 2022 Sep 21;225:109249. doi: 10.1016/j.exer.2022.109249. Online ahead of print. PMID: 36152913

miR204 potentially promotes non-alcoholic fatty liver disease by inhibition of cpt1a in mouse hepatocytes. Kim S, Lee I, Piao S, Nagar H, Choi SJ, Kim YR, Irani K, Jeon BH, Kim CS. Commun Biol. 2022 Sep 21;5(1):1002. doi: 10.1038/s42003-022-03945-1. PMID: 36130994

A clinically-guided unsupervised clustering approach to recommend symptoms of disease associated with diagnostic opportunities. Miller AC, Arakkal AT, Koeneman SH, Cavanaugh JE, Polgreen PM. Diagnosis (Berl). 2022 Sep 21. doi: 10.1515/dx-2022-0044. Online ahead of print. PMID: 36127310

Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart. Riehle C, Weatherford ET, McCarty NS, Seei A, Jaishy BP, Manivel R, Galuppo P, Allamargot C, Hameed T, Boudreau RL, Bauersachs J, Weiss RM, Abel ED. Mol Cell Biol. 2022 Sep 20:e0016322. doi: 10.1128/mcb.00163-22. Online ahead of print. PMID: 36125265

Risk of second primary malignancy in patients with primary myelofibrosis: a SEER database study. Joshi U, Bhattarai A, Gaire S, Gill S, Agrawal V, Yadav SK, Low SK, Dhakal P, Bhatt VR, Kouides PA. Leuk Lymphoma. 2022 Sep 18:1-6. doi: 10.1080/10428194.2022.2123227. Online ahead of print. PMID: 36120968

Effectiveness of Ultraviolet-C Disinfection on Hospital-Onset Gram-Negative Rod Bloodstream Infection: A Nationwide Stepped-Wedge Time-Series Analysis. Goto M, Hasegawa S, Balkenende EC, Clore GS, Safdar N, Perencevich EN. Clin Infect Dis. 2022 Sep 17:ciac776. doi: 10.1093/cid/ciac776. Online ahead of print. PMID: 36124706

Palliative Inotropes in Advanced Heart Failure: Comparing Outcomes Between Milrinone and Dobutamine. Sami F, Acharya P, Noonan G, Maurides S, Al-Masry AA, Bajwa S, Parimi N, Boda I, Tran C, Goyal A, Mastoris I, Dalia T, Sauer A, Van Bakel A, Shah Z. J Card Fail. 2022 Sep 16:S1071-9164(22)00711-4. doi: 10.1016/j.cardfail.2022.08.007. Online ahead of print. PMID: 36122816

September 1-15, 2022

Longitudinal clinical reasoning theme embedded across four years of a medical school curriculum. Rowat J, Suneja M. Diagnosis (Berl). 2022 Sep 12. doi: 10.1515/dx-2022-0046. Online ahead of print. PMID: 36082516

Days of Antibiotic Spectrum Coverage: A Novel Metric for Inpatient Antibiotic Consumption. Kakiuchi S, Livorsi DJ, Perencevich EN, Diekema DJ, Ince D, Prasidthrathsint K, Kinn P, Percival K, Heintz BH, Goto M. Clin Infect Dis. 2022 Sep 10;75(4):567-576. doi: 10.1093/cid/ciab1034. PMID: 34910130

The Wahls Behavior Change Model for Complex Chronic Diseases: A Clinician's Guide. Elliott-Wherry AN, Lee JE, Pearlman AM, Wahls TL. Degener Neurol Neuromuscul Dis. 2022 Sep 9;12:111-125. doi: 10.2147/DNND.S370173. eCollection 2022. PMID: 36110247

Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction. Yu W, Moninger TO, Rector MV, Stoltz DA, Welsh MJ. Dev Cell. 2022 Sep 8:S1534-5807(22)00596-2. doi: 10.1016/j.devcel.2022.08.010. Online ahead of print. PMID: 36108628

Zebrafish as an emerging tool for drug discovery and development for thyroid diseases. Yadav P, Sarode LP, Gaddam RR, Kumar P, Bhatti JS, Khurana A, Navik U. Fish Shellfish Immunol. 2022 Sep 6;130:53-60. doi: 10.1016/j.fsi.2022.09.001. Online ahead of print. PMID: 36084888 Review.

Phase Ib study of eprenetapopt (APR-246) in combination with pembrolizumab in patients with advanced or metastatic solid tumors. Park H, Shapiro GI, Gao X, Mahipal A, Starr J, Furqan M, Singh P, Ahrorov A, Gandhi L, Ghosh A, Hickman D, Gallacher PD, Wennborg A, Attar EC, Awad MM, Das S, Dumbrava EE. ESMO Open. 2022 Sep 6;7(5):100573. doi: 10.1016/j.esmoop.2022.100573. Online ahead of print. PMID: 36084396

PRC2 loss drives MPNST metastasis and matrix remodeling. Brockman QR, Scherer A, McGivney GR, Gutierrez WR, Voigt AP, Isaacson AL, Laverty EA, Roughton G, Knepper-Adrian V, Darbro B, Tanas MR, Stipp CS, Dodd RD. JCI Insight. 2022 Sep 6:e157502. doi: 10.1172/jci.insight.157502. Online ahead of print. PMID: 36066973

Association of Rapid Response Teams With Hospital Mortality in Medicare Patients. Girotra S, Jones PG, Peberdy MA, Vaughan-Sarrazin MS, Chan PS; American Heart Association GWTG-Resuscitation Investigators. Circ Cardiovasc Qual Outcomes. 2022 Sep 6:101161CIRCOUTCOMES122008901. doi: 10.1161/CIRCOUTCOMES.122.008901. Online ahead of print. PMID: 36065818

Facilitators of and Barriers to Adherence to Dietary Interventions Perceived by Women With Multiple Sclerosis and Their Support Persons. Dean C, Parks S, Titcomb TJ, Arthofer A, Meirick P, Grogan N, Ehlinger MA, Bisht B, Fox SS, Daack-Hirsch S, Snetselaar LG, Wahls TL. Int J MS Care. 2022 Sep-Oct;24(5):235-241. doi: 10.7224/1537-2073.2021-051. Epub 2022 May 26. PMID: 36090239

Tromethamine improves mucociliary clearance in cystic fibrosis pigs. Ash JJ, Hilkin BM, Gansemer ND, Hoffman EA, Zabner J, Stoltz DA, Abou Alaiwa MH. Physiol Rep. 2022 Sep;10(17):e15340. doi: 10.14814/phy2.15340. PMID: 36073059

Acute effects of euglycemic-hyperinsulinemia on myocardial contractility in male mice. Tadinada SM, Grzesik WJ, Kutschke W, Weiss RM, Abel ED. Physiol Rep. 2022 Sep;10(17):e15388. doi: 10.14814/phy2.15388. PMID: 36073057

PACT promotes the metastasis of basal-like breast cancer through Rac1 SUMOylation and activation. Wei L, Wang W, Yao J, Cui Z, Xu Z, Ding H, Wu X, Wang D, Luo J, Ke ZJ. Oncogene. 2022 Sep;41(37):4282-4294. doi: 10.1038/s41388-022-02431-6. Epub 2022 Aug 16. PMID: 35974143

Treating hospitalized people who have opioid use disorder: Coming to consensus. Mosher H. J Hosp Med. 2022 Sep;17(9):774-775. doi: 10.1002/jhm.12928. Epub 2022 Aug 7. PMID: 35934924 No abstract available.

Mitochondrial Ca2+ Uptake Drives Endothelial Injury By Radiation Therapy. Ait-Aissa K, Koval OM, Lindsey NR, Grumbach IM. Arterioscler Thromb Vasc Biol. 2022 Sep;42(9):1121-1136. doi: 10.1161/ATVBAHA.122.317869. Epub 2022 Jul 28. PMID: 35899616

Patient Sense of Belonging in the Veterans Health Administration: A Qualitative Study of Appointment Attendance and Patient Engagement. Lafferty M, Strange W, Kaboli P, Tuepker A, Teo AR. Med Care. 2022 Sep 1;60(9):726-732. doi: 10.1097/MLR.0000000000001749. Epub 2022 Jul 26. PMID: 35880766

More Evidence Links Microglia and Neuroinflammation With Hypertension. Cheng L, Correia MLG. Am J Hypertens. 2022 Sep 1;35(9):787-789. doi: 10.1093/ajh/hpac081. PMID: 35815792 No abstract available.

Percutaneous closure of patent foramen ovale for treatment of hypoxemia: A case series and physiology review. Robl J, Vutthikraivit W, Horwitz P, Panaich S. Catheter Cardiovasc Interv. 2022 Sep;100(3):471-475. doi: 10.1002/ccd.30317. Epub 2022 Jun 27. PMID: 35758238

Progression-Free Survival at 24 Months as A Landmark After Autologous Stem Cell Transplant in Relapsed or Refractory Diffuse Large B-cell Lymphoma. Tun AM, Maliske S, Wang Y, Inwards DJ, Habermann TM, Micallef I, Porrata L, Paludo J, Bisneto JV, Rosenthal A, Kharfan-Dabaja MA, Ansell SM, Nowakowski GS, Farooq U, Johnston PB. Transplant Cell Ther. 2022 Sep;28(9):610-617. doi: 10.1016/j.jtct.2022.06.015. Epub 2022 Jun 22. PMID: 35752441

Voluntary Exercise Eliminates Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization to Postweaning High-Fat Diet in Male Adult Offspring. Xue B, Yu Y, Beltz TG, Guo F, Wei SG, Johnson AK. Hypertension. 2022 Sep;79(9):2016-2027. doi: 10.1161/HYPERTENSIONAHA.122.19608. Epub 2022 Jun 22. PMID: 35730432

Breast Cancer Epidemiology and Contemporary Breast Cancer Care: A Review of the Literature and Clinical Applications. El Masri J, Phadke S. Clin Obstet Gynecol. 2022 Sep 1;65(3):461-481. doi: 10.1097/GRF.0000000000000721. Epub 2022 Jun 9. PMID: 35703213 Review.

Association of rheumatoid arthritis with mortality in chronic kidney disease: a cohort study. Ezeanuna MN, Prince DK, Alexander SA, Richards JS, Kerr GS, Jalal D, Bansal N, Liew JW, Singh N. Clin Rheumatol. 2022 Sep;41(9):2669-2676. doi: 10.1007/s10067-022-06223-x. Epub 2022 May 25. PMID: 35610408

Reference Intervals for Clinical Chemistry Analytes for Transgender Men and Women on Stable Hormone Therapy. Humble RM, Greene DN, Schmidt RL, Winston McPherson G, Rongitsch J, Imborek KL, Nisly N, Dole NJ, Dane SK, Frerichs J, Krasowski MD. J Appl Lab Med. 2022 Sep 1;7(5):1131-1144. doi: 10.1093/jalm/jfac025. PMID: 35584132

Catheter directed thrombolysis for deep vein thrombosis in 2022: Rationale, evidence base and future directions. Khalid MU, Singh M, Lakhter V, Bashir R. Int J Cardiol. 2022 Sep 1;362:168-173. doi: 10.1016/j.ijcard.2022.04.081. Epub 2022 Apr 30. PMID: 35500821

Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function. Harris MP, Zhang QJ, Cochran CT, Ponce J, Alexander S, Kronemberger A, Fuqua JD, Zhang Y, Fattal R, Harper T, Murry ML, Grueter CE, Abel ED, Lira VA. Autophagy. 2022 Sep;18(9):2161-2177. doi: 10.1080/15548627.2021.2022289. Epub 2022 Feb 1. PMID: 35104184

TREM-1 is required for enhanced OpZ-induced superoxide generation following priming. Murthy S, Baruah S, Bowen JL, Keck K, Wagner BA, Buettner GR, Sykes DB, Klesney-Tait J. J Leukoc Biol. 2022 Sep;112(3):457-473. doi: 10.1002/JLB.3A0421-212R. Epub 2022 Jan 24. PMID: 35075692

Highlights of mechanisms and treatment of obesity-related hypertension. Shams E, Kamalumpundi V, Peterson J, Gismondi RA, Oigman W, de Gusmão Correia ML. J Hum Hypertens. 2022 Sep;36(9):785-793. doi: 10.1038/s41371-021-00644-y. Epub 2022 Jan 10. PMID: 35001082 Review.

Effects of Tham Nasal Alkalinization on Airway Microbial Communities: A Pilot Study in Non-CF and CF Adults. Holliday ZM, Launspach JL, Durairaj L, Singh PK, Zabner J, Stoltz DA. Ann Otol Rhinol Laryngol. 2022 Sep;131(9):1013-1020. doi: 10.1177/00034894211051814. Epub 2021 Oct 21. PMID: 34674574

Translation and preliminary validation of a French version of an ageism scale for dental students. Piaton S, Barlow P, Kossioni A, Tubert-Jeannin S, Marchini L. Gerodontology. 2022 Sep;39(3):291-296. doi: 10.1111/ger.12583. Epub 2021 Jul 17.

PMID: 34275154