Alexander G. Bassuk, MD, PhD

Portrait
Professor of Pediatrics - Neurology
Professor of Neurology

Contact Information

Primary Office: 2040 ML
200 Hawkins Drive
Iowa City, IA 52242
319-356-7726

Education

AB, Fundamentals: Issues and Texts, University of Chicago
PhD, Biological Sciences Pathology, University of Chicago
MD, University of Chicago Pritzker School of Medicine

Resident, Pediatrics, Children's Memorial Hospital, Northwestern University
Resident, Pediatric Neurology, Children's Memorial Hospital, Northwestern University

Education/Training Program Affiliations

Interdisciplinary Graduate Program in Genetics, Interdisciplinary Graduate Program in Molecular and Cellular Biology, Interdisciplinary Graduate Program in Neuroscience, Medical Scientist Training Program

Research Summary

Congenital defects of the nervous system, especially neural tube defects, familial epilepsy, neurogenetics, neural stem cell biology Our laboratory is interested in understanding the basic mechanisms underlying both normal and disordered development of the nervous system. Our approach to these issues includes investigating the genetics of human neural tube defects (NTDs) and familial epilepsies, and elucidating the biology regulating neural stem cell development. The techniques used in our laboratory include genome wide linkage analysis (GWA), association studies, comparative genomic hybridization (CGH), copy number variation (CNV) analysis, transgenic mouse production, and cell culture. As part of our studies we have collected DNA samples from over 2000 patients and family members with congenital nervous system malformations, and several large families with autosomal recessive epilepsy syndromes.