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Genome Sequencing

The IIHG Genomics Division provides genomic or massively parallel DNA sequencing using the Illumina platform. Investigators can submit RNA/DNA samples for library preparation and sequencing, or submit their own prepared libraries for sequencing.  A custom LIMS facilitates sample management throughout the workflow provides users access to information regarding sample preparation along with their sequencing results. A powerful computer cluster supports data analysis and members of the IIHG Bioinformatics Division perform a preliminary analysis (e.g., assembly, alignment, etc.) on all runs.  All data are back up and archived.  

The applications supported by the division include:

  • RNA-Seq (mRNA and ribo-depleted Total RNA sequencing) 
  • Whole Exome Sequencing 
  • Custom Target Sequencing
  • Whole Genome Sequencing
  • smRNA discovery and quantification
  • ChIP-Seq
  • Single-Cell RNA-Seq (single-cell expression profiling) 

Contact Information

116 EMRB
Phone: (319) 335-6736 
Fax: (319) 335-6737 
dna-genomeseq@uiowa.edu

For information about downstream bioinformatics support, contact the IIHG Bioinformatics Division (319) 335-6717.