Gamma interferon given 24 hours before and up to 24 hours after exposure completely protects mice from death from Ebola

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

University of Iowa scientists will develop a pig model for Neurofibromatosis type 1 to improve understanding of the disease and advance therapy

A University of Iowa research team will develop an innovative pig model to better understand a rare genetic disorder called neurofibromatosis (NF) thanks to a $931,395 grant from the Children’s Tumor Foundation (CTF). The funding is part of a three-year, $1.7 million grant that the CTF has...

Study links changes in gut bacteria to lower resting metabolic rate and weight gain in mice

The link between the gut microbiome and obesity seems clear, but just how changes to gut bacteria can cause weight gain is not. A University of Iowa study in mice shows that drug-induced changes to the gut microbiome can cause obesity by reducing the resting metabolic rate—the rate at which calories are burned while sleeping or resting.