Address: 2-340 BSB
Phone: 335-8926
Email: madeliene-stump@uiowa.edu
Mentor: Curt D. Sigmund, PhD
Undergraduate Institution: Slippery Rock University
Graduate Program: Neuroscience | Medical Scientist Training Program
Year Entered Into Program: 2011
Research Description
The role of Peroxisome proliferator-activated receptor-gamma in neural control of feeding and energy homeostasis
Publication(s)
- Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD.: Hypertension-causing mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-kB p65 in Vascular Smooth Muscle. Hypertension. 70(1):174-182, 2017. PMCID: PMC5472224 [Available on 2018-07-01]
- Stump M, Guo DF, Lu KT, Mukohda M, Cassell MD, Norris AW, Rahmouni K, Sigmund CD.: Nervous System Expression of PPARγ and Mutant PPARγ Has Profound Effects on Metabolic Regulation and Brain Development. Endocrinology 157(11):4266-4275, 2016. PMCID: PMC5086539
- Stump M, Guo DF, Lu KT, Mukohda M, Liu X, Rahmouni K, Sigmund CD.: Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance. Physiol Genomics 48(7):491-501, 2016. PMCID: PMC4967222
- Ketsawatsomkron P, Keen HL, Davis DR, Lu KT, Stump M, De Silva TM, Hilzendeger AM, Grobe JL, Faraci FM, Sigmund CD.: Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension. Hypertension 67(1):214-22, 2016. PMCID: PMC4679422
- Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD.: Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress. Am J Physiol Heart Circ Physiol 310(1):H39-48, 2016. PMCID: PMC4796462
- Stump M, Mukohda M, Hu C, Sigmund CD.: PPARγ Regulation in Hypertension and Metabolic Syndrome. Curr Hypertens Rep 17(12):89, 2015. PMID: 26462805
- Kreple CJ, Lu Y, Taugher RJ, Schwager-Gutman AL, Du J, Stump M, Wang Y, Ghobbeh A, Fan R, Cosme CV, Sowers LP, Welsh MJ, Radley JJ, LaLumiere RT, Wemmie JA.: Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity. Nat Neurosci 17(8):1083-91, 2014. PMCID: PMC4115047