Chris S. Jensen, MD

Portrait
Director of Cytopathology
Director, Cytopathology Fellowship Program
Clinical Professor of Pathology

Contact Information

Primary Office: 5238-B Roy Carver Pavilion
Iowa City, IA 52242
319-356-3217

Education

BS, Zoology, Iowa State University, Ames, IA
MD, University of Iowa College of Medicine

Resident, Anatomic and Clinical Pathology, University of Iowa Hospitals and Clinics
Fellow, Surgical Pathology, University of Iowa Hospitals and Clinics
Fellow, Cytopathology, University of Iowa Hospitals and Clinics

Licensure and Certifications

American Board of Pathology Special Certification in Cytopathology - American Board of Pathology
American Board of Pathology Certification in Anatomic and Clinical Pathology - American Board of Pathology
State of Iowa Medical License - Iowa Board of Medicine

Research Summary

Performing and interpreting fine needle aspiration biopsies, gyn and non-gyn cytopathology, and surgical pathology with special interest in gastrointestinal and liver. Dr. Jensen is interested in teaching fellows, residents and medical students through an interactive service-based approach. He has a particular interest in cytopathology by way of correlations with surgical pathology. Additionally, he emphasizes the role of surgical pathology and cytology in the clinical decision making process.

Publications

Sandhu, D. S., Holm, A. N., El-Abiad, R., Rysgaard, C., Jensen, C. & Gerke, H. (2017). Endoscopic ultrasound with tissue sampling is accurate in the diagnosis and subclassification of gastrointestinal spindle cell neoplasms. Endoscopic ultrasound, 6(3), 174-180. PMID: 28621294.

Amog-Jones, G. F., Chandra, S., Jensen, C. & Johlin, F. C. (2017). Including the Sheath Rinse to Improve Cellular Yield in Biliary Brushing Cytology. Clinical endoscopy, 50(6), 614-616. PMID: 29207855.

Reed, M. J., Sperry, S. M., Gailey, M. P., Jensen, C. S., Robinson, R. A., Funk, G. F. & Pagedar, N. A. (2016). Correlating thyroid cytology and histopathology: Implications for molecular testing. Head Neck. PMID: 26900030.

Gailey, M. P., Bellizzi, A. M. & Jensen, C. S. (2016). Differentiating Small Cell Carcinoma From Squamous Cell Carcinoma in Cytologic Specimens: A Head-to-Head Comparison of p40 and p63 Using Cell Block Immunocytochemistry. Appl Immunohistochem Mol Morphol, 24(1), 11-15. PMID: 25906121.

Stence, A. A., Gailey, M. P., Robinson, R. A., Jensen, C. S. & Ma, D. (2015). Simultaneously detection of 50 mutations at 20 sites in the BRAF and RAS genes by multiplexed single-nucleotide primer extension assay using fine-needle aspirates of thyroid nodules. Yale J Biol Med, 88(4), 351-358. PMID: 26604858.

Gailey, M. P., Bellizzi, A. & Jensen, C. S. (2015). Differentiating small cell carcinoma from squamous cell carcinoma in cytological specimens: a head-to-head comparison of p40 and p63 using cell block immunocytochemistry. Appl Immunohistochem Mol Morphol.. PMID: 25906121.

Gao, L., Darbro, B., Jensen, C. s. & Bossler, A. (2014). FGFR3 Mutational Analysis in Urinary Tract Cytology Specimens with Abnormal UroVysion. Association for Molecular Pathology (AMP).

Gailey, M. P., Stence, A. A., Jensen, C. S. & Ma, D. (2014). Multiplatform comparison of molecular oncology tests performed on cytology specimens and formalin-fixed, paraffin-embedded tissue. Cancer Cytopathol. PMID: 25186473.

Keeney, M., Gailey, M. P. & Jensen, C. S. (2014). FNA of granulomas: a view of the workd beyond the lungs and infectious etiologies. San Diego, CA: USCAP.

Gailey, M. P., Jensen, C. S. (2013). Histoplasmosis: Have EUS and EBUS FNA Changed the Cytologic Face of the Disease?. (26 (S2)), pp. 90A. Mod Path.

Jensen, C. S. (2013). Histoplasmosis: Have EUS and EBUS FNA Changed the Cytologic Face of the Disease?. USCAP Meeting.

Jensen, C. S. (2013). Fine-needle aspiration of histoplasmosis in the era of endoscopic ultrasound and endobronchial ultrasound: Cytomorphologic features and correlation with clinical laboratory testing. Cancer Cytopathol. PMID: 23677891.

Tryggvason, G., Gailey, M., Hulstein, S., Karnell, L., Jensen, C. S. & Van Daele, D. (2013). Role of fine needle aspiration biopsy and imaging in the preoperative workup of salivary gland mass lesions. Laryngoscope, 123(1), 158-163.

Jensen, C. S. (2012). Cytology and Pitfalls of EUS Sampling of Ectopic Splenic Tissue. (Vols. 25). (S2), pp. 99A. Mod Path.

Jensen, C. S. (2012). Comparison of fine needle aspiration biopsy and imaging in the preoperative workup of salivary gland mass lesions. (Vols. 25). (S2), pp. 108A. Mod Path.

Jensen, C. S. (2012). TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: Potential role of TRPM8 as a biomarker and target. (1), pp. 13(8).

Jensen, C. S. (2012). Role of fine needle aspiration biopsy and imaging in the preoperative workup of salivary gland mass lesions. (10), pp. 1002/lary.23613. Laryngoscope.

Jensen, C. S. (2011). Prospective Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration Processed as Cell-Block Using High Suction versus Regular Suction. DDW.

Savage, E. C., Vanderheyden, A. D., Bell, A. M., Syrbu, S. I. & Jensen, C. S. (2011). Independent diagnostic accuracy of flow cytometry obtained from fine-needle aspirates: a 10-year experience with 451 cases. American journal of clinical pathology, 135(2), 304-9. PMID: 21228371.

Ebach, D. R., Vanderheyden, A. D., Ellison, J. M. & Jensen, C. S. (2011). Lymphocytic esophagitis: a possible manifestation of pediatric upper gastrointestinal Crohn's disease. Inflammatory bowel diseases, 17(1), 45-9. PMID: 20848529.

Jensen, C. S. (2011). A possible manifestation of pediatric upper gastrointestinal Crohn disease. Inflamm Bowel Dis,(17), 45-49.

Gerke, H., Siddiqui, J., Nasr, I., Van Handel, D. M. & Jensen, C. S. (2011). Efficacy and safety of EMR to completely remove Barrett's esophagus: experience in 41 patients. Gastrointestinal endoscopy, 74(4), 761-71. PMID: 21824611.

Jensen, C. S. (2011). Independent Diagnostic Accuracy of Flow Cytometry Obtained from Fine Needle Aspirates. Am J Clin Pathol,(135), 304-309.

Fang, S. H., Guidroz, J. A., O'Malley, Y., Lal, G., Sugg, S. L., Howe, J. R., Jensen, C. S. & Weigel, R. J. (2010). Expansion of a cell population expressing stem cell markers in parathyroid glands from patients with hyperparathyroidism. Annals of surgery, 251(1), 107-13. PMID: 20009751.

Jensen, C. S. (2010). Further Classification of Epithelial Lesions of the Salivary Gland. (23), pp. 92A. Mod Pathol.

Gerke, H., Rizk, M. K., Vanderheyden, A. D. & Jensen, C. S. (2010). Randomized study comparing endoscopic ultrasound-guided Trucut biopsy and fine needle aspiration with high suction. Cytopathology : official journal of the British Society for Clinical Cytology, 21(1), 44-51. PMID: 19456845.

Jensen, C. S. (2009). Identification of Stem Cell Expansion in Parathyroid Glands from Patients with Hyperparathyroidism. American Association of Endocrine Surgeons Meeting.

Jensen, C. S. (2009). Amended report worksheets in surgical pathology. (S1), pp. 364A. Mod Pathol.

Jensen, C. S. (2009). Fine Needle Aspiration Cytology of Cervical Sympathetic Chain Schwannoma with Discussion of Differential Diagnosis of a Mass Lesion at the Birfurcation of the Common Carotid Artery. (Vols. 37). (5), pp. 55-71. ASCP Cytopathology.

Ali, S., Wilkinson, N., Jensen, C. S. & Gerke, H. (2009). EUS-guided Trucut biopsies may enable the diagnosis of lymphoepithelial cysts of the pancreas. Report of two cases. JOP : Journal of the pancreas, 10(4), 409-12. PMID: 19581745.

Lueck, N., Jensen, C. S., Cohen, M. B. & Weydert, J. A. (2009). Mandatory second opinion in cytopathology. Cancer, 117(2), 82-91. PMID: 19466754.

Jensen, C. S. (2008). Long-term, tumor-free survival after radiotherapy combining hepatectomy-Whipple en bloc and orthotopic liver transplantation for early stage hilar cholangiocarcinoma. Liver Transplantation,(14), 279-286.

Jensen, C. S. (2008). Lymphocytic Esophagitis in Pediatric Inflammatory Bowel Disease: A Manifestation of Upper Gastrointestinal Crohn Disease. (S1), pp. 139A. Mod Pathol.

Jensen, C. S. (2008). Mandatory Second Opinion in Cytopathology Referral Material. (S1), pp. 356A. Mod Pathol.

Jensen, C. S. (2008). Independent Diagnostic Accuracy of Flow Cytometry of FNA: A 10 Year Experience with 511 cases. (S1), pp. 86A. Mod Pathol.

Jensen, C. S. (2008). Prospective, Randomized Study Comparing Endoscopic Ultrasound Guided Trucut Biopsy and Fine-needle Aspiration with High Suction for Histologic Yield and Diagnostic Accuracy. University of Iowa Hospitals and Clinics Department of Medicine Research Day.

Jensen, C. S. (2008). EUS-Guided Trucut Biopsies May Enable The Diagnosis Of Lymphoepithelial Cysts Of The Pancreas (Case Report). American College of Gastroenterology Annual Scientific Meeting.

Jensen, C. S. (2008). The value of touch imprint cytology in endoscopic ultrasound guided trucut biopsy. (S1), pp. 86A. Mod Pathol.

Vanderheyden, A. D., Proctor, K. A., Rizk, M. K., Silva, R. G., Jensen, C. S. & Gerke, H. (2008). The value of touch imprint cytology in EUS-guided Trucut biopsy. Gastrointestinal endoscopy, 68(1), 44-50. PMID: 18355821.

Jensen, C. S. (2008). Prospective, Randomized Study Comparing Endoscopic Ultrasound Guided Trucut Biopsy and Fine-needle Aspiration with High Suction for Histologic Yield and Diagnostic Accuracy. Digestive Disease Week, San Diego, CA.

Jensen, C. S. (2008). Urothelial Cell Clusters in Voided Urine Cytology Specimens: A Histologic and Cytologic Review of 146 Patients. (S1), pp. 90A. Mod Pathol.

Jensen, C. S. (2008). Effect of Double Viewing Needle Core Prostate Biopsy Tissues on Error Reduction. (S1), pp. 358A. Mod Path.

Jensen, C. S. (2007). Cardiac angiosarcoma: an unusual cause of malignant pericardial effusion with discussion of differential diagnosis. (Vols. 35). (10), pp. 7-10. ASCP Cyopthatology.

Jensen, C. S. (2007). Sensitization of colon mechanoreceptors is associated with long-term hypersensitivity to colon distention in the mouse. Gastroenterology,(133), 184-194.

Jensen, C. S. (2007). Increasing Incidence of Hepatic Adenoma in Men. (20), pp. 294A. Mod Pathol.

Rahhal, R. M., Banerjee, S. & Jensen, C. S. (2007). Pediatric Crohn disease presenting as an esophageal stricture. Journal of pediatric gastroenterology and nutrition, 45(1), 125-9. PMID: 17592376.

Jensen, C. S. (2007). Improving Interobserver Reproducibility in Pap Test. (20), pp. 337A. Mod Pathol.

Raab, S. S., Grzybicki, D. M., Zarbo, R. J., Jensen, C. S., Geyer, S. J., Janosky, J. E., Meier, F. A., Vrbin, C. M., Carter, G. & Geisinger, K. R. (2007). Frequency and outcome of cervical cancer prevention failures in the United States. American journal of clinical pathology, 128(5), 817-24. PMID: 17951205.

Jensen, C. S. (2007). Utility of EUS-guided trucut biopsy to distinguish pancreatic rests from gastrointestinal stromal tumor (a case series). American College of Gastroenterology.

Jensen, C. S. (2007). Effectiveness of Cervical Cancer Screening Using Correlation Analysis. (20), pp. 80A. Mod Pathol.

Jensen, C. S. (2007). Cytologic diagnosis of parathyroid adenoma by EUS guided mediastinal FNA. (Vols. 35). (9), pp. 7-9. ASCP Cytopathology.

Jensen, C. S. (2007). Should Negative Pap Tests Be Reviewed in Patients. (20), pp. 65A. Mod Pathol.

Jensen, C. S. (2007). The Impact of Endocervical Cytologic Sampling (Endopap) on Cytologic-Histologic Correlation (CHC) Error Rates. (20), pp. 205A. Mod Pathol.

Cai, G., Grzybicki, D. M., Jensen, C. S., Zarbo, R. J., Carter, G. & Raab, S. S. (2007). Should Negative Pap Tests Be Reviewed in Patients with a Newly Diagnosed Endometrial, Cervical or Vaginal Adenocarcinoma?. (20), pp. 65A. Mod Pathol.

Jensen, C. S. (2006). Perineural and vascular invasion on colorectal carcinoma: comparison of detection methods to clinical outcome. (19), pp. 323A. Mod Pathol.

Jensen, C. S. (2006). The agency for healthcare research and quality hospital labs studying patient safety (AHRQ-HLPS) consortium and error reduction. Am J Clin Pathol Pathology Patterns Review,(126), S12-20.

Jensen, C. S. (2006). Urinary cytology of clear cell adenocarcinoma: Review of the differential diagnosis and cytologic features with histologic correlation. (34), pp. 10. ASCP Cytolopathology.

Jensen, C. S. (2006). Urinary cytology of clear cell adenocarcinoma: Review of the differential diagnosis and cytologic features with histologic correlation. (34), pp. 10. ASCP Cytolopathology.

Gao, L., Pruessner, J. A., Stence, A. A., Guseva, N. V., Zubcic, M. T., Hackman, J. R., Ford, S., Jensen, C. S. & Bossler, A. FGFR3 Mutation in Archival Urinary Tract Cytology Specimens: A Simple Method for Detection with {reservation of Cytomorphology. San Diego, CA: USCAP.

Gailey, M. P., Bellizzi, A. & jensen, C. S. Differentiating Small Cell Carcinoma from Squamous Cell Carcinoma on Fine Needle Aspiration: A Head-To-Head Comparison of p40 and p63 Using Cell Block Immunocytochemistry. San Diego, CA: USCAP.

Jensen, C. S. (2006). Double slide viewing as a quality improvement initiative. (19), pp. 323A. Mod Pathol.

Jensen, C. S. (2006). FNA diagnosis as salivary gland neoplasm, not otherwise specified (NOS) has a high association with malignancy. (19), pp. 53A. Mod Pathol.

Gerke, H., Silva, R. G., Shamoun, D., Johnson, C. J. & Jensen, C. S. (2006). EUS characteristics of celiac ganglia with cytologic and histologic confirmation. Gastrointestinal endoscopy, 64(1), 35-9. PMID: 16813800.

Gerke, H., Silva, R. & Jensen, C. S. (2006). Hypervascular pancreatic tumor diagnosed as a serous cystadenoma by EUS-guided Trucut biopsy. Gastrointestinal endoscopy, 64(2), 273-4. PMID: 16860085.

Raab, S. S., Meier, F. A., Zarbo, R. J., Jensen, C. S., Geisinger, K. R., Booth, C. N., Krishnamurti, U., Stone, C. H., Janosky, J. E. & Grzybicki, D. M. (2006). The "Big Dog" effect: variability assessing the causes of error in diagnoses of patients with lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24(18), 2808-14. PMID: 16782918.

Raab, S. S., Stone, C. H., Jensen, C. S., Zarbo, R. J., Meier, F. A., Grzybicki, D. M., Vrbin, C. M., Ohori, N. P. & Dahmoush, L. (2006). Double slide viewing as a cytology quality improvement initiative. American journal of clinical pathology, 125(4), 526-33. PMID: 16627263.

Jensen, C. S. (2006). Celiac ganglion cells on endoscopic ultrasound guided fine-needle aspiration: a possible. (19), pp. 60A. Mod Pathol.

Jensen, C. S. (2006). Case series in anatomic pathology From the University of Iowa: A 50-year-old woman with a breast Lesion and a 70-year-old man with abdominal pain - CME Case, Medscape, MEDLINE and Drug Reference. http://medscape.com/viewprogram/5504.

Jensen, C. S. (2005). Clinical impact and frequency of anatomic pathology errors in cancer diagnoses. Cancer,(104), 2205-2213.

Raab, S. S., Grzybicki, D. M., Zarbo, R. J., Meier, F. A., Geyer, S. J. & Jensen, C. S. (2005). Anatomic pathology databases and patient safety. Archives of pathology & laboratory medicine, 129(10), 1246-51. PMID: 16196512.

Joudi, F. N., Austin, J. C., Vogelgesang, S. A. & Jensen, C. S. (2004). Isolated testicular vasculitis presenting as a tumor-like lesion. The Journal of urology, 171(2 Pt 1), 799. PMID: 14713819.

Jensen, C. S. (2004). Urinary Tract Cytology. In B. Atkinson (Eds.) Atlas of Diagnostic Cytopathology. (2nd)

Jensen, C. S. (2003). Two-way interactive video conferencing: An effective tool for delivering distance education in cytotechnology. (46), pp. 1021. Acta Cytol.

Jensen, C. S. (2003). Performance of AutoCyte PREP system for gynecologic cytology in a community practice. (46), pp. 955. Acta Cytol.

Jensen, C. S. (2003). Brush cytology using autocyte-preparation in the assessment of pancreato-biliary strictures - A review of 399 cases. (16), pp. 72A. Mod Pathol.

Jensen, C. S. (2002). Immunocytochemistry of AutoCyte? preparations of body fluids. (15), pp. 79A. Mod Pathol.

Jensen, C. S. (2002). Cytologic diagnosis of adenocarcinoma in biliary and pancreatic duct brushings. Advances in Anatomic Pathology, 9(5), 301-308.

Henke, A. C., Jensen, C. S. & Cohen, M. B. (2002). Cytologic diagnosis of adenocarcinoma in biliary and pancreatic duct brushings. Advances in anatomic pathology, 9(5), 301-8. PMID: 12195219.

Silverman, W. B., Jensen, C. S., Crook, T. W. & Henke, A. (2002). Bile duct brushings in a pig model: examination of intraobserver variability and variability in specimen quality obtained in sequential animals and between two different brushes. International journal of gastrointestinal cancer, 32(1), 31-4. PMID: 12630767.

Jensen, C. S. (2001). Ultrasound transmission gel: an important artifact in ultrasound guided thyroid fine needle aspirations. (45), pp. 876. Acta Cytol.

Jensen, C. S. (2001). Morphologic features in preliminary evaluation of neck lymph node aspirates influencing decision to perform flow cytometry (FC). (14), pp. 58A. Mod Pathol.

Henke, A. C., Kelley, C. M., Jensen, C. S. & Timmerman, T. G. (2001). Fine-needle aspiration cytology of pancreatoblastoma. Diagnostic cytopathology, 25(2), 118-21. PMID: 11477717.

Jensen, C. S. (2001). Clear cell change in hepatocellular carcinoma with non-hepatocellular carcinoma of the liver on fine needle aspiration. (45), pp. 857. Acta Cytol.

Jensen, C. S. (2001). Autocyte preparation of urinary tract fluids reduces the rate of “atypical” diagnoses. (14), pp. 50A. Mod Pathol.

Jensen, C. S. (2001). Inhibin immunostaining of FNA cell block material does not help characterize malignant neoplasms involving the adrenal gland. (14), pp. 64A. Mod Pathol.

Jensen, C. S. (2001). FNA of spindle cell lesions of the head and neck. (45), pp. 86. Acta Cytol.

Jensen, C. S. (2001). Fine needle aspiration (FNA) of cystic lesions of the head and neck: cytologic feature for diagnosis. (14), pp. 50A. Mod Pathol.

Jensen, C. S. (2000). Jaws revisited (or give piece a chance): A comparison of three different biopsies on porcine colon mucosa - Was there a difference?. American College of Gastroenterology.

Hughes, J. H., Jensen, C. S., Donnelly, A. D., Cohen, M. B., Silverman, J. F., Geisinger, K. R. & Raab, S. S. (1999). The role of fine-needle aspiration cytology in the evaluation of metastatic clear cell tumors. Cancer, 87(6), 380-9. PMID: 10603192.

Raab, S. S., Robinson, R. A., Jensen, C. S., Ozkutlu, D., O'Reilly, P. O., Savell, V. H. & Thomas, P. A. (1997). Mucinous tumors of the ovary: interobserver diagnostic variability and utility of sectioning protocols. Archives of pathology & laboratory medicine, 121(11), 1192-8. PMID: 9372748.

Raab, S. S., Zaleski, M. S., Thomas, P. A., Niemann, T. H., Isacson, C. & Jensen, C. S. (1996). Telecytology: diagnostic accuracy in cervical-vaginal smears. American journal of clinical pathology, 105(5), 599-603. PMID: 8623769.

Jensen, C. S. (1996). Transitional cell carcinoma: cytologic criteria to improve diagnostic accuracy. Modern Pathology, 9(225).

Raab, S. S., Slagel, D. D., Jensen, C. S., Teague, M. W., Savell, V. H., Ozkutlu, D., Lenel, J. C. & Cohen, M. B. (1996). Low-grade transitional cell carcinoma of the urinary bladder: application of select cytologic criteria to improve diagnostic accuracy [corrected]. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 9(3), 225-32. PMID: 8685219.

Jensen, C. S. (1995). Telecytology: Diagnostic accuracy in cervical-vaginal smears with comparison to conventional light microscopy. (8), pp. 41A. Mod Pathol.

Jensen, C. S. (1995). Low grade transitional cell carcinoma (TCCA) of the bladder: Improved accuracy using key cytologic features. (8), pp. 44A. Mod Pathol.

Jensen, C. S. (1995). The role of fine needle aspiration (FNA) cytology in the workup of metastatic clear cell tumors. (8), pp. 41A. Mod Pathol.

Jensen, C. S. (1994). Editorial comments (renal cyst aspiration). (11), pp. 383. Diagnostic Cytopathology.

Mohler, C. G., Jensen, C. S., Steyers, C. M., Landas, S. K. & Renfrew, D. L. (1994). Osteosarcoma of the hand: a case report and review of the literature. The Journal of hand surgery, 19(2), 287-9. PMID: 8201196.

Jensen, C. S. (1992). Ileal conduit urinary cytology. (Vols. 3). (Cytology II), pp. 8. ASCP.

Jensen, C. S. (1992). Flow cytometric studies of expression and regulation in lymphoblastoid cell lines. (5), pp. 107A. Mod Pathol.

Jensen, C. S. (1992). Bone marrow transplant patients do not have large numbers of blood or bone marrow Epstein-Barr virus infected cells. (98), pp. 36. Am J Clin Pathol.