Dean's List Archives

 

2022: JanuaryFebruaryMarchAprilMayJuneJulyAugustSeptemberOctoberNovemberDecember

December 2022

New Federal Awards

Gordon Buchanan

Neurology

NIH R01 - 5 years

Serotonergic circuit mechanisms in postictal recovery and arousal

Kamal Rahmouni

Neuroscience & Pharmacology

NIH R01 - 4 years

Role of FGF21 Action in Hypothalamic Neurons in Obesity-Associated Hypertension

Rainbo Hultman

Molecular Physiology & Biophysics

NIH R25 - 4 years

Iowa-Diversifying Research And Mentorship (iDREAM)

Yuriy Usachev

Neuroscience & Pharmacology

NIH R01 - 5 years

Novel Circuits and Mechanisms of Descending Pain Modulation

Competitive Awards

Barcey Levy

Family Medicine

Duke Clinical Research Institute

Iowa UH3 Subaward Low Back Pain Clinical Coordinating Center (IMPACt-LBP CCC)

Other Awards 

Ali Jabbari

Dermatology

Pfizer Global Research & Development

A study of RYZ101 compared with standard of care therapy in subjects with SSTR+ and GEP-NET that has treatment with 177Lu-DOTATATE/TOC.

David Bushnell

Radiology

RayzeBio, Inc.

A study of RYZ101 compared with standard of care therapy in subjects with SSTR+ and GEP-NET that has treatment with 177Lu-DOTATATE/TOC.

David Elliott

Internal Medicine

IQVIA RDS Inc.

A Phase 2 Study to Evaluate the Efficacy and Safety of TAK-062 for the Treatment of Active Celiac Disease in Subjects Attempting a Gluten-Free Diet

Mohammad Bashir

Cardiothoracic Surgery

CytoSorbents Corporation

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)

Nicholas Mohr

Emergency Medicine

University of California, Los Angeles

EMERGEncy ID NET: Preventing Emerging Infections through Vaccine Effectiveness Testing II-COVID (PREVENT II)Data Coordinating Center & Supplement

Saima Sharif

Internal Medicine

CTI Clinical Trial Services, Inc.

A Phase 1b/2 Placebo Controlled, Double Blinded Study on the Efficacy and Safety of BXQ-350 in Combination with mFOLFOX7 and Bevacizumab in Newly Diagnosed Metastatic Colorectal Carcinoma

Spyridon Fortis

Internal Medicine

AstraZeneca Pharmaceuticals LP

A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of MEDI3506 in Participants with Symptomatic Chronic Obstructive Pulmonary Disease (COPD)

Usha Perepu

Internal Medicine

Medpace Clinical Research, LLC

A phase 3 study of the Hepcidin Mimetric Rusfertide (PTG-300) in patients with Polycythemia Vera.

November 2022

New Federal Awards

Don Anderson

Orthopedics

AHRQ R18 – 5 years

Integrating Next Generation Simulator Training and Operating Room Performance Assessment into Orthopedic Residency Programs

Mariah Hassert

Pathology

NIH F32 – 2 years

Antiviral lung resident memory T-cell maintenance and reinvigoration

Alison Lynch

Psychiatry

SAMHSA H79 – 5 years

Recovery and Empowerment to Combat Opioids delivered by telehealth and collaboration across Iowa (RECOVER-IA)

Scott Moye-Rowley

Physiology

NIH R21 – 2 years

Chemical genetic analysis of Candida glabrata CDR1 expression

Amy Ryan

Anatomy & Cell Biology

NIH R01 (Transfer) – 5 years

Characterization of mechanisms regulating multiciliated cell specification using patient-specific induced pluripotent stem cells

Hanora Van Ert

Microbiology

NIH F32 – 2 years

Determining Tropism and Mechanisms of Ebola Virus Entry in Placental Tissues

Competitive Awards

Michael Shy

Neurology

Charcot-Marie- Tooth Association

The virologic efficacy of REGN10933+REGN10987 across different dose regimens in outpatients with SARS-CoV-2

Other Awards

Sabarish Ayyappan

Internal Medicine

Genmab US Inc.

Safety and Efficacy of GEN3009 in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Gordon Buchanan

Neurology

Cure Epilepsy

960831 Nighttime mechanisms for SUDEP

Joseph Caster

Radiation Oncology

DeGregorio Family Foundation

Manipulating redox metabolism with pharmacologic ascorbate and superoxide dismutase mimetics to enhance the efficacy of chemoradiation for locally advanced esophageal adenocarcinoma.

Joseph Dillon

Internal Medicine

Crinetics Pharmaceuticals

A Randomized, Parallel Group Study to Evaluate the Safety, Pharmacokinetics, and Dose Response of Paltusotine Treatment in Subjects with Carcinoid Syndrome.

Janet Fairley

Dermatology

AstraZeneca Pharmaceuticals LP

Maintenance of pluripotency in ferret to evaluate autologous cell therapy

Umar Farooq

Internal Medicine

Arsenal Biosciences

A phase-one study to evaluate the safety and efficacy of AB-1015 in patients with platinum-resistant epithelial ovarian cancer

Nicole Fleege

Internal Medicine

ASCO Foundation

2020 Conquer Cancer - Rising Tide Foundation for Clinical Cancer Research Career Pathway Grant in Symptom Management

David Gordon

Pediatrics

Hyundai Hope on Wheels

990458 Targeting Impaired Differentiation in Ewing Sarcoma Tumors

Mohammed Milhem

Internal Medicine

PHILOGEN S.p.A.

Study of The Efficacy of Daromun Neoadjuvant Intratumoral Treatment Followed by Surgery and Adjuvant Therapy Versus Surgery and Adjuvant Therapy in Clinical Stage IIIB/C Melanoma Patient

Nicholas Mohr

Emergency Medicine

Vanderbilt University Medical Center

COVID: Adult Inpatient SARS-CoV-2 Vaccine Effectiveness Surveillance (IVY 5)

Amy Ryan

Anatomy & Cell Biology

Cystic Fibrosis Foundation

Maintenance of pluripotency in ferret to evaluate autologous cell therapy

OCTOBER 2022

New Federal Awards

Masaaki Kurahashi

Internal Medicine

NIH R01 - 2 years

Inhibitory mechanisms of PDGFRa+ interstitial cells in gastrointestinal motility

Bing Li

Pathology

NIH R01 - 2 years

Immunomodulatory mechanisms of E-FABP in psoriasis pathogenesis

Nandakumar Narayanan

Neurology

NIH P20 - 2 Years

Prefrontal Cortex, Cognition, and Speech Symptoms in PD (PRECIS-PD)

Jennifer Power

Dermatology

DoD, CDMRP - 3 Years

ME200128 - Establishing the Role of Deployments in Melanoma in the Military

Andrea Weber, Contact PI
Joshua Radke, MPI

Psychiatry and Emergency Medicine

SAMHSA H79 - 3 Years

Training Expansion in Addiction Medicine and Medications for Addiction Treatment at the University of Iowa (TEAM-MAT-UI)

Other Awards

Chandrikha Chandrasekharan

Internal Medicine

Merck Sharp & Dohme Corp.

A Phase 2 Study to Evaluate the Efficacy and Safety of MK-6482 Monotherapy in Participants with Advanced Pheochromocytoma/Paraganglioma (PPGL) and Pancreatic Neuroendocrine Tumor (pNET)

Umar Farooq

Internal Medicine

Artiva Biotherapeutics, Inc.

A Multi-Center, Open-Label, Phase 1/2 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-101 Monotherapy and AB-101 Plus Rituximab in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma of B-Cell Origin

Mony Fraer

Internal Medicine

Covance, Inc.

A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients with Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Huy Tran

Internal Medicine

Exact Sciences Corporation

ALTUS: PERFORMANCE OF A MULTI-TARGET HEPATOCELLULAR CARCINOMA (HCC) TEST IN SUBJECTS WITH INCREASED RISK

SEPTEMBER 2022

Competitive Renewal

William Sivitz

Internal Medicine

Case Western Reserve University

Epidemiology of Diabetes Interventions and Complications (EDIC)

New Federal Awards

Chih-Jen Cheng

Internal Medicine

NIH R01 - 5 years

Exploring the pathogenesis of classic Bartter syndrome

Dao-Fu Dai

Pathology

NIH R01 - 5 years

Metabolic reprogramming and FGF21 signaling in kidney health and polycystic kidney diseases

John Engelhardt

Anatomy and Cell Biology

NIH C06 - 5 years

National Ferret Research and Resource Institute (NFRRI) at University of Iowa

Carl Andrew Frank

Anatomy and Cell Biology

NIH R01 - 5 years

How discrete homeostatic signals stabilize synapse function across time.

Zizhen Kang

Pathology

NIH R21 - 2 years

Understanding the role of LRRK2 G2019S-mediated gut-brain axis in the pathogenesis of Parkinson's disease

Vincent Magnotta

Radiology

NIH R01 - 5 years

Suicidality in Bipolar and Major Depression Disorders

Wendy Maury

Steven Varga

Microbiology 

NIH UH2 - 2 years

Elucidating mechanisms of interferon gamma that protect against Ebola virus infection

Seongjin Seo

Opthamology and Visual Sciences

NIH R01 - 4 years

Compartmentalized protein localization in photoreceptors

Ryan Zander

Microbiology 

NIH R00 - 2 years

Defining the transcriptional, phenotypic, and functional heterogeneity of virus specific CD4 T cells during chronic viral infection

Qiang Zhang

Neurology

NIH R03 - 2 years

Glycolysis and Alzheimer's Disease 

Other Awards

Chris Ahern

Molecular Physiology & Biophsyics

hC Bioscience, Inc.

hC Bioscience

Ferhaan Ahmad

Internal Medicine

AavantiBio

Cytokinetics, Inc.

Ahmad/AAvantiBio-Gene Therapy For Inherited Dilated Cardiomyopathy (DCM)

Trial to Evaluate the Efficacy and Safety of CK3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

Michael Anderson

Molecular Physiology & Biophysics 

BrightFocus Foundation

Testing the Influence of Podosomes on Intraocular Pressure

Linda Cadaret

Internal Medicine

Acceleron Pharma, Inc. 

ZENITH

Michael Ciliberto 

Pediatrics

PPD Investigator Services, LLC

Studies To Assess the Long-Term Safety and Tolerability of Soticlestat as Adjunctive Therapy in Subjects With Dravet Syndrome or Lennox-Gastaut Syndrome (ENDYMION 2)

Bruce Gantz

Otolaryngology Head Neck Surgery

Cochlear Americas

Investigation to evaluate the safety and effectiveness of cochlear implantation in children and adults with unilateral hearing loss/single-sided deafness 

Marlan Hansen

Matthew Howard

Samuel Young

Otolaryngology Head Neck Surgery

Neurosurgery

Anatomy and Cell Biology

AskBio

Recombinant AAV capsid library screening to identify clinically relevant capsid variants in humans

Sarat Kuppachi

Internal Medicine

CSL Behring L.L.C. 

A Pivotal Phase 3 Trial to Evaluate the Safety and Efficacy of Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients

Katherine Mathews 

Pediatrics

Edgewise Therapeutics, Inc. 

EDG-5506-201 Medpace - EDG-5506-201: A Phase 2 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of EDG-5506 on Safety, Biomarkers, Pharmacokinetics, and Functional Measures in Adults and Adolescents with Becker Muscular Dystrophy

Varun Monga

Internal Medicine

ADC Therapeutics

A Phase 1b, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Mipasetamab Uzoptirine (ADCT-601) Monotherapy and in Combination with Other Anti-Cancer Therapies in Patient

Michael Shy

Neurology

Charcot-Marie-Tooth Association

CMT2F Biomarkers and Outcome Measures

Yousef Zakharia

Internal Medicine 

AstraZeneca AB

A Phase I/IIa First-in-human, Open-label, Modular Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AZD8853 in Participants with Selected Advanced/Metastatic Solid Tumours

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AUGUST 2022

Competitive Renewal

Craig Ellermeier

Microbiology

NIH R01 - 4 years

Identification of daptomycin resistance mechanisms in Clostridioides difficile

Chou-Long Huang       

Internal Medicine

NIH R01

WNK kinase cascade in health and disease

Robert Piper

Molecular Physiology & Biophysics

NIH R01

Ubiquitin-dependent sorting in endosomes and the TGN

New Federal Awards

Stephen Baek

Radiation Oncology

DoD, Army - 1 year

Microstructure-aware Reaction Models for PBXs in the Weak-to-Moderate Shock Regime 

Valentina Botero

Neuroscience & Pharmacology

NIH F31 - 2 years

Neuronal mechanisms of neurofibromin-mediated modulation of metabolic homeostasis

Amy Conrad

Pediatrics

NIH R56 - 1 year

Brain Development and Pre-Speech Function in Infants with Isolated Oral Clefts: Relationship to Anesthesia Exposure and Oxygenation

Mark Greiner

Opthamology and Visual Sciences

NIH R21 - 2 years

Optimizing Rho-associated kinase inhibitors for use in treating Fuchs endothelial corneal dystrophy

James Holmes

Radiology

NIH R01 - 5 years

Simultaneous MRI/US for real-time liver ablation guidance and confirmation

Bing Li

Pathology

NIH U01 - 5 years

Determine the molecular and metabolic mechanisms by which A-FABP links  dysregulated lipid metabolism-induced obesity/breast cancer risk

Nathaniel Mullin

Inst for Vision Research

NIH R21 - 2 years

Pathogenesis of Mitochondrial Retina Disease

Amy Ryan

Anatomy and Cell Biology

NIH R01 (Transfer) - 3 years & 1 year

Characterization of mechanisms regulating multiciliated cell specification using patient-specific induced pluripotent stem cells

Quantitative analysis of mucociliary clearance in airway ciliopathies      

Miranda Schene

Molecular Physiology & Biophysics

NIH F03 - 4 years

Using a Molecular Toolkit to Examine Potassium Channel Gating and Regulation

Kristina Thiel 

OBGyn

NIH K22 - 3 years

Attacking aggressive p53 mutants in gynecologic cancer

Budd Tucker

Opthamology and Visual Sciences

NSF - 4 years

Collaborative Research: RECODE: Microfluidic and genetic technologies to direct and select retinal cell types from human induced pluripotent stem cell-derived retinal organoids

Andrea Weber

Psychiatry

HRSA H79 - 3 years

Longitudinal Integration and Virtual Expansion of Rural Substance Use Disorder and Liver Disease Treatment in Iowa (LIVER-SUD-IA)

Jason Wilken

Physical Therapy & Rehab Sciences

DoD, CDMRP - 2 years

OP210037 - Carbon Fiber Orthosis Cuff Design

Lok-Yin Roy Wong

Microbiology

NIH K99 - 2 years

Phenotypic and functional characterization of Betacoronavirus Internal protein in relation to virulence

Ling Yang

Anatomy and Cell Biology

NIH R01 - 4 years

Role of ADH5 in the Regulation of Brown Adipose Tissue Metabolic Homeostasis

Other Awards

Umar Farooq

Internal Medicine

Syneos Health, LLC

A Phase 1 Safety and Efficacy Study of ADI-001 Anti-CD20 CAR-engineered Allogeneic Gamma-Delta () T Cells in Adults with B-Cell Malignancies.

Douglas Fredericks 

Orthopaedic Surgery

Surgentec

EFFICACY OF SURGENTEC BONE PUTTY AS A BONE VOID FILLER IN A RABBIT METAPHYSEAL DEFECT MODEL

Margarida Magalhaes-Silverman

Internal Medicine

Medspace Clinical Research, LLC

A randomized, double-blind trial to evaluate the safety and efficacy of apraglutide in subjects with Grade II to IV (MAGIC) steroid refractory gastrointestinal (GI) acute graft versus host disease on best available therapy

Katherine Mathews

Pediatrics

Capricor Therapeutics

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL EVALUATING THE EFFICACY AND SAFETY OF HUMAN ALLOGENEIC CARDIOSPHERE-DERIVED CELLS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY (HOPE-3)

Delwyn Miller

Psychiatry

University of Southern California/NIH

Long-Term Nicotine Treatment of Mild Cognitive Impairment

Sneha Phadke

Internal Medicine

AstraZeneca Pharmaceuticals LP

A Phase 1b Multicentre, Open-label, Modular, Dose-finding and Dose-expansion Study to Explore the Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Trastuzumab Deruxtecan (T-DXd) in Combination with Other Anti-cancer Agents in Patients wi

Michael Shy

Neurology

Applied Therapeutics, Inc.

Clinical Trial - SORD Study AT-007-1005

Grerk Sutamtewagul

Internal Medicine

Novartis Corporation

A phase III, multi-center, open-label, randomized study of oral asciminib versus Investigator selected TKI in patients with newly diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase

Elizabeth Takacs 

Urology

Medtronic, Inc.

TITAN 2

Yousef Zakharia 

Internal Medicine

Bristol-Myers Squibb Company

A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy with Relatlimab and Nivolumab Fixed-dose Combination versus Nivolumab Monotherapy after Complete Resection of Stage III-IV Melanoma

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JULY 2022

Competitive Renewal

Marlan Hansen

Otolaryngology

NIH T32 - 5 years

Research Training Program in Otolaryngology

New Federal Awards

Gail Bishop

Microbiology and Immunology

NIH R01 - 4 years

Regulation of B cell signaling in autoimmunity by TRAF3

David Kaczka

Anesthesia

DoD, CDMRP - 3 years

Preclinical Evaluation of Multi-Frequency Oscillatory Ventilation in a Large Animal Model of Acute Respiratory Failure

Damian Krysan

Pediatrics

NIH R01 - 5 years

Discovery and development of antifungal acetyl CoA synthetase inhibitors

George Richerson

Neurology

NIH R01 - 5 years

Prevention of SUDEP by milk whey: Role of CO2 chemoreception and serotonin

Rasna Sabharwal

Internal Medicine

NIH 1 R21 - 2 years

RAS-Driven Central Inflammation and Cognitive Decline with Aging.

Dong Rim Seol

Orthopaedics and Rehabilitation

NIH R03 - 2 years

Exosome-based Cell Homing and Lineage-Specific Differentiation Strategies for Dental Pulp Regeneration

Douglas Spitz
Val Sheffield

Radiation Oncology

NIH R21 - 2 years

Evaluation of Orthogonally Oriented Electromagnetic Fields to Stabilize ROS, Induce DNA damage and Improve Survival in Non-Small Cell Lung Cancer

Michael Wright

Molecular Phyusiology and Biophysics

NIH 1 R01 - 4 years

Construction of the Androgen Receptor Interactome: A Molecular Framework for Probing Genetic Interactions in Androgen-Dependent Signaling

Other Awards

Muhammad Furqan

Internal Medicine

PPD Investigator Services, LLC

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Comparing Niraparib Plus Pembrolizumab Versus Placebo Plus Pembrolizumab as Maintenance Therapy in Participants Whose Disease has Remained Stable or Responded to First-Line Platinu

Nabeel Hamzeh

Internal Medicine

Genentech, Inc

A Phase III Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of PRM-151 in Patients with Idiopathic Pulmonary Fibrosis

Sharon Larson

Surgery

CryoLife, Inc

A prospective, randomized, active (warfarin) controlled, parallel-arm clinical trial to determine if patients with and On-X aortic valve can be maintained safely and effectively on the factor Xa inhibitor apixaban

Katherine Mathews

Pediatrics

FIbroGen, Inc

A Phase 3, Randomized, Double-Blind, Trial of Pamrevlumab (FG-3019) or Placebo in Combination with Systemic Corticosteroids in ambulatory subjects with Duchenne Muscular Dystrophy (DMD

Sidakpal Panaich

Internal Medicine

Edwards Lifesciences, LLC

Edwards PASCAL CLASP II TR Pivotal Clinical Trial

Patricia Winokur

Internal Medicine

Pfizer, Inc

A Study to Evaluate Additional Dose(s) of BNT162b2 in Healthy Individuals  Previously Vaccinated With BNT162b2

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JUNE 2022

Competitive Renewal

Evan Abel

Andrew Norris

Internal Medicine

Pediatrics

NIH T32 - 5 years

Diabetes Research Training Program

John Engelhardt

Anatomy and Cell Biology

NIH R01 - 4 years

Biology of submucosal gland stem cells in the airway

Yumi Imai

Internal Medicine

NIH R01 - 4 years

Role of lipid droplet proteins in islet function in diabetes and obesity

Alison Lynch

Psychiatry

HRSA D40 - 3 years

Graduate Psychology Training in Integrated Mental Health and Substance Use Treatment for Rural Iowa Youth

New Federal Awards

Toshihiro Kitamoto

George Richerson

Anesthesia

Neurology

NIH R21 - 2 years

Effects of dietary alpha-linolenic acid on SUDEP, seizures, and neural structure and function in mouse models of epilepsy

Jessica Skeie

Ophthalmology

NSF - 1 year

I-Corps: Novel Antioxidant Ocular Therapeutic

Other Awards

Don Anderson

Orthopedics 

Stryker Orthopaedics

Mechanical Tradeoffs in Implant Design, Implantation Choices, Impingement-Free Range of Motion, Joint Stability, Muscle Force Requirements, and Subluxation Risk After Reverse Shoulder Arthroplasty with the Stryker/Tornier Perform System

Lovkesh Arora

Anesthesia 

Edwards Lifesciences LLC

HPI SMART- BP Trial: Hypotension Prediction Index Software Guided Hemodynamic Management for Noncardiac Surgery Patients - Blood Pressure Trial

Linda Cadaret

Internal Medicine

Acceleron Pharma, Inc. 

A Phase 3, Randomized, Double-blind, Placebo controlled Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy in Newly Diagnosed Intermediate- and High-risk PAH Patients (HYPERION)

Chandrikha Chandrasekharan

Internal Medicine

Novartis Corporation

A randomized, double-blind, phase III study comparing NIS793 in combination with gemcitabine and nab-paclitaxel versus placebo combined with gemcitabine and nab-paclitaxel for first line treatment of metastatic pancreatic ductal adenocarcinoma (mPDAC)

Daniel Diekema

Internal Medicine

bioMerieux, Inc.

First in Human Phase 1 /2 Trial of ELI-002 Immunotherapy as Treatment for Subjects with Kirsten Rat Sarcoma (KRAS) Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors

Mohammed Milhem

Internal Medicine

Checkmate Pharmaceuticals

VITEK Evolution Compact Instrument Clinical Trial, and Reproducibility Data Collection for VITEK 2 Instrument Protocol

Brad Dixon

Internal Medicine

Bayer HealthCare Pharmaceuticals Inc.

A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of FInerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kid

Umar Farooq

Internal Medicine

Janssen Research & Development, Inc.

A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA versus Bortezomib, Lenalidomide, and Dexamethasone (VRd)

Yusuf Menda

Radiology

Clovis Oncology, Inc.

Fusion Pharmaceuticals, Inc.

A Phase 1/2, Multicenter, Open-label, Non-randomized Study to Investigate Safety and Tolerability, Pharmacokinetics, Dosimetry, and Preliminary Activity of 177Lu-FAP-2286 in Patients with an Advanced Solid Tumor

A Phase 1/2 Study of [225Ac]-FPI-1966, [111In]-FPI-1967, and Vofatamab in Participants with FGFR3-expressing Advanced, Inoperable, Metastatic and/or Recurrent Solid Tumours

Brendan Patterson

Orthopedics

Stryker Orthopaedics

Mechanical Tradeoffs in Implant Design, Implantation Choices, Impingement-Free Range of Motion, Joint Stability, Muscle Force Requirements, and Subluxation Risk After Reverse Shoulder Arthroplasty with the Stryker/Tornier Perform System

Antonio Sanchez 

Internal Medicine

Boehringer Ingelheim Pharmaceuticals, Inc.

Randomised, double-blind, placebo-controlled and parallel group trial to investigate the effects of two doses (up-titration to a fixed dose regimen) of oral BI 685509 on portal hypertension after 24 weeks treatment in patients with clinically significant 

Michael Willey

Orthopedics

Excere Medical LLC

Bispectral EEG in Early Detection/Prediction of Delirium (Phase 1 Device Validation)

Yousef Zakharia 

Internal Medicine

Merck Sharp & Dohme LLC

A Phase 1b/2 Study of Immune and Targeted Combination Therapies in Participants With RCC

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MAY 2022

Competitive Renewals

Kathleen Sluka

Yuriy Usachev

Physical Therapy

Neuroscience & Pharmacology

NIH T32 - 5 years

Interdisciplinary Training Program in Pain Research

New Federal Awards

Alejandro Pezzulo

Internal Medicine

NIH R01 - 5 years

Epigenetic mechanisms of inflammatory memory propagation in human airway epithelia

Allan Anderson

Robert Philibert

Psychiatry

NIH R21 - 2 years

Predicting Alcohol Withdrawal using DNA Methylation

Dong Rim Seol

Orthopedics

NIH R21 - 2 year

Preventive and Therapeutic Effects of Bone Marrow Stem Cell-Derived Exosomes on Spine Dural Fibrosis

Erica Gansemer 

Orthopedics

NIH F32 - 1 year

The role of NADPH production in regulating endoplasmic reticulum function and the progression of non-alcoholic steatohepatitis

Hasem Habelhah

Pathology

NIH R01 - 5 years

The roles of TRAF2 and RIP1 in breast cancer cell survival

Samuel Young

Anatomy & Cell Biology

NIH R03 - 1 year

Elucidating the roles of CACNA2D2 and CACNA2D3 in presynaptic regulation of mammalian synaptic function

Stefan Strack

Neuroscience & Pharmacology

NIH T32 - 5 years

Predoctoral Training in the Pharmacological Sciences

Other Awards

Alejandro Pezzulo

Internal Medicine

Ann Theodore Foundation

Personal Response Profiles in Sarcoidosis

Chandrikha Chandrasekharan

Internal Medicine

Syros Pharmaceuticals

A Phase 1 Study of SY-5609, an Oral, Selective CDK7 Inhibitor, in Adult Patients With Select Advanced Solid Tumors

Janice Staber

Pediatrics

Saliogen Therapeutics, Inc. 

Gene Coding Therapy for Hemophilia A

Manasa Nayak

Internal Medicine

American Heart Association

942168 Novel role of Pyruvate Kinase M2 in experimental Deep Vein Thrombosis

Mel Sharafuddin

Surgery

Endologix, Inc.

JAGUAR Trial:  ObJective Analysis to GaUge EVAR Outcomes Through Randomization

Michael Ciliberto 

Pediatrics

Stoke Therapeutics, Inc.

An Open-Label Extension Study for Patients with Dravet Syndrome who Previously Participated in Studies of STK-001

Michael Wall

Opthamology

Invex Therapeutics, Inc. 

Consulting Agreement with Invex Therapeutics, Ltd

Micahel Welsh

Internal Medicine

Edward N. & Della L. Thome Memorial Foundation

Developing Novel Agents that Enhance Energy Metabolism for Alzheimer's Disease

Mohammed Milhem

Internal Medicine

BicycleTX Limited

Phase 1/2 Study of the Safety, Pharmacokinetics, and Preliminary Clinical Activity of BT7480 in Patients With Nectin-4 Associated Advanced Malignancies

Rohan Garje

Internal Medicine

PSI Pharma Support America, Inc. 

SPLASH: Study Evaluating Metastatic Castrate Resistant Prostate Cancer Using 177Lu-

Santiago Ortega Gutierrez

Neurology

Stryker Neurovascular

Safety and Efficacy Assessment of Surpass EVOLVE (SEASE) Study

Sean Fain

Radiology

Genetech, Inc.

129Xe MRI Assessment Of Disease Progression In Patients With Chronic Obstructive Pulmonary Disease Treated With Standard-Of-Care Medications With Or Without Daily Open-Label Azithromycin Treatment To Prevent Acute Exacerbation

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APRIL 2022

Competitive Renewals

Jack T. Stapleton

Internal Medicine

HRSA H76 - 3 years

OP EARLY INTERVENTION SERVICES WITH RESPECT TO HIV DISEASE

New Federal Awards

Budd Albert Tucker

Edward M. Stone

Robert F. Mullins

Ophthamology

NIH FO1

A Next Generatoion Outer Retinal Microphysiological System

David A. Stoltz

Lynda Spencer Ostedgaard

Internal Medicine

NIH R01 - 4 years

Testing the Contributions of Airway Submucosal Glands and Surface Epithelia to Lung Health

Joseph Vecchi

Molecular Physiology

NIH F31 - 2 years

Feature characteristics and signaling mechanisms involved in SGN neurite guidance by engineered topographical and biochemical micropatterns

Grant Donald Brown

Nicholas Matthew Mohr

Santiago Gutierrez

Biostatistics

NIH R01 - 5 years

Testing the Contributions of Airway Submucosal Glands and Surface Epithelia to Lung Health

Sheila Annetta

Biochemistry 

NIH R21 - 2 years

In vivo metabolic labeling of photoreceptor proteins

Other Awards

Alejandro Comellas

Internal Medicine

Laurent Pharmaceuticals, Inc.

RESOLUTION: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, PHASE II STUDY OF THE EFFICACY AND SAFETY OF LAU-7b IN THE TREATMENT OF ADULT HOSPITALIZED PATIENTS WITH COVID-19 DISEASE_Phase2

Daniel James Diekema

Internal Medicine

bioMerieux, Inc.

VITEK 2 and VITEK 2 Compact GN24 Antimicrobial Susceptibility Tests

Eric Alfred Hoffman

Radiology

Trustees of Columbia University

Precision phenotyping of emphysema in the elderly: the MESA Lung Study

Hanna Dominika Zembrzuska

Internal Medicine

AbbVie, Inc. 

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABBV-154 in Subjects With Moderately to Severely Active Rheumatoid Arthritis With Inadequate Response to Biologic and/or Targeted Synthetic Disease-Modifying Anti-

Huy T T Tran

 

Internal Medicine

Pharmaceutical Research Associates

 

A randomised, double-blind, placebo-controlled, multicentre, Phase 3 study evaluating long-term efficacy and safety of lanifibranor in adult patients with non-cirrhotic non-alcoholic steatohepatitis (NASH) and fibrosis 2 (F2)/fibrosis 3 (F3) stage of live

Jon Michael Resch

Neuroscience & Pharmacology

American Heart Association

The basis for aldosterone-mediated activation of hindbrain NTS Hsd11b2 neurons

Kathleen E. Dlouhy

Neurosurgery

Medtronic, Inc. 

EMBOLIZATION OF THE MIDDLE MENINGEAL ARTERY WITH ONYXTM LIQUID EMBOLIC SYSTEM IN THE TREATMENT OF SUBACUTE AND CHRONIC SUBDURAL HEMATOMA (EMBOLISE) STUDY

Paul B. McCray

Pediatrics

Spirovant Sciences, Inc. 

LV-mediated ABCA3 gene expression for correction of the ABCA3 deficiency phenotype

Qian Shi

Internal Medicine

American Heart Association

Novel role of Insulin receptor substrate 2 (IRS2) in the maintenance of calcium homeostasis in the heart

 Rohan Garje

Internal Medicine

Exelixis, Inc.

A Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics  of XL092 as Single-Agent and Combination Therapy in Subjects with  Inoperable Locally Advanced or Metastatic Solid Tumors

Sean B. Fain

Radiology

Duke University

Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis

Tracey A. Cho

Neurology

Massachusetts General Hospital

NeuroNEXT Clinical Trial:  A Phase-2b, Double-Blind, Randomized Controlled Trial to Evaluate the Activity and  Safety of Inebilizumab in Anti-N-methyl-D-aspartate receptor (NMDAR) Encephalitis and Assess  Markers of Disease

Varun Monga

Internal Medicine

Trillium Therapeutics Inc.

A Phase I/II Study of TTI-621 in Combination with Doxorubicin in Patients with Unresectable or Metastatic High-Grade Leiomyosarcoma

Umar Farooq

Internal Medicine

FATE Therapeutics

A Phase I Study of FT819 in Subjects with B-cell Malignancies

Xingshen Sun

Anatomy & Cell Biology

Emily's Entourage

Therapeutic Utility of DNP for Cystic Fibrosis using MP-101 compound in ferrets

Yousef Zakharia 

Internal Medicine 

Castle Biosciences, Inc.

Pfizer, Inc.

Prognostic Gene Expression Profiling and Adjuvant Therapy in Stage IIIA-B Cutaneous Melanoma (PERSONALize)

Phase 1 of escalating doses of Seleno-L-methionine (SLM) in sequential combination with a fixed doses and schedule of axitinib and pembrolizumab(SAP) in untreated patients with clear cell Renal Cell Carcinoma (ccRCC)

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MARCH 2022

New Federal Awards

Jon Houtman
Steven Varga

Microbiology and Immunology

NIH R21 - 2 years

CD4 T cell intrinsic signaling defects during viral exhaustion

Nandakumar Narayanan

Neurology

NIH R01 - 5 years

VTA dopamine neurons and cognitive symptoms of Parkinson's

Adam Mailloux

Microbiology and Immunology

NIH R21 - 1 year

Autohistomagnetic Isolation of Tumor-reactive T-cells

Craig Ellermeier

Microbiology and Immunology

NIH R21 - 2 years

Regulation of the C. difficile cell envelope by Two-component systems

Alexander Boyden

Pathology

NIH R21 - 2 years

Role of B cell interactions in CNS autoimmune demyelination

Claudia Mello-Thoms

Radiology

NIH R01 - 5 years

Satisfaction of Search in Breast Cancer Detection

Philip Polgreen

Internal Medicine

NIH R01 - 5 years

Estimating the risk for and severity of respiratory infections attributable to CFTR hterozygosity

Prajwal Gurung

Internal Medicine

NIH R01 - 5 years

Implicating a previously unknown Dectin1-RIPK2-CARD9 signaling in providing resistance against Leishmania major infection

Pamela Geyer

Biochemistry and Molecular Biology

NIH R21 - 2 years

Aging and the nuclear lamina in mitotic stem cells

Other Awards

Chris Ahern

Molecular Phyusiology and Biophysics

University of Wisconsin-Madison

Restoring vision with high-fidelity nonsense codon correction

Sabarish Ayyappan

Internal Medicine

Genmab US Inc

A Trial of GEN3013 in Patients with Relapsed, Progressive or Refractory B-Cell Lymphoma

Sabarish Ayyappan

Internal Medicine

Regeneron Pharmaceuticals, Inc

A study to assess the anti-tumor activity and safety of regn1979, an anti-cd20 x anti-cd3 bispecific antibody, in patients with relapsed or refractory b-cell non-Hodgkin lymphoma

Linda Cadaret

Internal Medicine

Gossamer Bio, Inc

Evaluating the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

John Engelhardt

Anatomy and Cell Biology

Cystic Fibrosis Foundation

Development of Cystic Fibrosis Models in the Ferret

Muhammad Furqan

Internal Medicine

Inhibrx, Inc

A Phase 1 Study of INBRX-106 in Subjects with Locally Advanced or Metastatic Solid Tumors

Nicholas Mohr

Anesthesia

Vanderbilt University Medical Center

COVID: Adult Inpatient SARS-CoV-2 Vaccine Effectiveness Surveillance

Varun Monga

Internal Medicine

Pfizer, Inc

A trial evaluating pharmacokinetics, safety and efficacy of pf 07284890 (arry 461) in participants with BRAF v600 mutant solid tumors with and without brain involvement

Douglas Van Daele

Otolaryngology

Nyxoah SA

Assessing the safety and effectiveness of the GenioTM dual-sided hypoglossal nerve stimulation system for the treatment of obsructive sleep apnea in adult subjects (DREAM)

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FEBRUARY 2021

New Federal Awards

Jordan Schulz

Psychiatry

NIH K23 - 5 years

Autonomic Dysfunction as Early Pathologic Feature of Huntington's Disease

Ron Weigel
Tiandao Li
Junlin Liao

Surgery

DoD, CDMRP - 3 years

SUMO Inhibition Represses Mammary Oncogenesis Through Etv1

Other New Awards

Camille Dunn-Johnson

Otolaryngology

MED-EL Corporation

Single-Sided Deafness and Asymmetric Hearing Loss

John Engelhardt

Anatomy and Cell Biology

Cystic Fibrosis Foundation

Regenerative Properties of Airway Submucosal Gland Stem Cell Niches

Douglas Laux

Internal Medicine

Replimune, Inc

Cemiplimab as a single agent and in combination with RP1 in patients with advanced cutaeneous squamous cell carcinoma

Enrique Leira

Neurology

Massachusetts General Hospital

StokeNet: Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery (DISCOVERY)

Varun Monga

Internal Medicine

Medical College of Wisconsin

Abemaciclib for Treatment of Advanced Bone and Soft Tissue Sarcoma Identified as having CDK Pathway Alteration (BOAST)

Muhammad Furqan

Internal Medicine

Hoosier Cancer Research Network, Inc

Chemo-immunotherapy Followed by Combo of Durvalumab and ATRi in Treatment Naïve Patients with Extensive Stage Small Cell Lung Cancer

Muhammad Furqan

Internal Medicine

Bristol-Myers Squibb Company

First-in-human of BMS-986258 Alone and in Combo with Nivolumab in Advanced Tumors

Muhammad Furqan

Internal Medicine

Aprea Therapeutics

APR-246 in Combination with Pembrolizumab in Subjects with Solid Tumor Malignancies

Lucy Wibbenmeyer

Surgery

Avita Medical Americas, LLC

Regenerative Epidermal Suspension Prepared with the RECELL Device Compared to Standard of Care Dressings for Treatment of Partial

Pat Winokur

Internal Medicine

Sanofi Pasteur, Inc

Immunogenicity and Safety of the First-in-Human SARS-CoV-2 mRNA Vaccine Formulation in Healthy Adults 18 Years of Age and Older

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January 2022

New Federal Awards

Jennifer Bermick

Pediatrics

NIH R01 transfer - 5 years

Targeting iron to improve outcomes in neonatal Escherichia coli sepsis

Zizhen Kang

Pathology

NIH R01 transfer - 2 years

Integration of IL-17 and notch signaling in the pathogenesis of CNS inflammation

Stanely Perlman

Microbiology and Immunology

NIH T32 - 5 years

Training in Molecular Virology, Viral Pathogenesis and Viral Vectors

Jon Resch

Neuroscience and Pharmacology

NIH R00 - 3 years

Central Regulation of sodium appetite via synergistic action of RAAS-sensitive neurons

Shunguang Wei

Internal Medicine

NIH R01 - 4 years

Novel Role of Interleukin-17 in Sympathetic Activation in Heart Failure

Other Awards 

Alejandro Comellas

Internal Medicine

Regeneron Pharmaceuticals, Inc

The virologic efficacy of REGN10933+REGN10987 across different dose regimens in outpatients with SARS-CoV-2

Muhammad Furqan

Internal Medicine

PPD Investigator Services, LLC

Autologous T-Cells expressing enhanced TCRs specific for NY-ESO-1/LAGE-1a alone or in combo with pembrolizumab

Margarida Magalhaes-Silverman

Internal Medicine

Marker Therapeutics, Inc

Donor-derived multi-tumor-associated antigen-specific T Cells administered to patients with AML following hematopoietic stem cell transplantation

Philip Polgreen

Internal Medicine

University of Maryland

Gathering new contact network data to inform interventions designed to Decrease the Spread of COVID-19

Antonio Sanchez

Internal Medicine

Merck Sharp & Dohme Corp

Efficacy and Safety of MK-3655 in Individuals with Pre-cirrhotic Nonalcoholic Steatohepatitis